1P0AA

Nmr structure of etd135, mutant of the antifungal defensin ard1 from archaeoprepona demophon
Total Genus 8
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
8
sequence length
44
structure length
44
Chain Sequence
DKLIGSCVWGAVNYTSNCNAECKRRGYKGGHCGSFLNVNCWCET
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Lead optimization of antifungal peptides with 3D NMR structures analysis.
pubmed doi rcsb
molecule tags Antifungal protein
source organism Archaeoprepona demophon
molecule keywords DEFENSIN ARD1
total genus 8
structure length 44
sequence length 44
ec nomenclature
pdb deposition date 2003-04-10
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.30.10 Alpha Beta 2-Layer Sandwich Defensin A-like Knottin, scorpion toxin-like 1p0aA00
1TI5A 1FH3A 1ZYVA 1BK8A 2KBKA 1T7BA 2GL1A 2BRZA 1SN4A 1I2UA 2KPYA 1T1TA 1AHOA 1N4NA 4HHFA 1LQQA 1T7EA 1PTXA 2LY6A 2E0HA 1ZVGA 2KSKA 1BMRA 4V1DC 1I6FA 2LT8A 1LQHA 1CN2A 1B7DA 2LY5A 5KK4A 1DQ7A 1ZVEA 1GPSA 1NH5A 1T0ZA 1NPIA 5CY0A 2A7TA 2YEOA 1OZZA 1ZFUA 2ASCA 1I2VA 2N2QA 1DJTA 2YC1C 1L4VA 1KV0A 1SNBA 1WMTA 3PSMA 1T7AA 2B68A 1B3CA 2KBHA 4KYPA 1PX9A 1VNBA 1JZAA 4AAZA 2LJ7A 1P00A 2NY8X 2ATBA 2LKBA 2N66A 2SN3A 1LQIA 2KJAA 1ZU3A 2N69A 1NRBA 1JXCA 2B3CA 2LJMA 3E7RL 1AYJA 1SN1A 2KGQA 2YBRC 1SEGA 2NY9X 3E7UX 2MZ0A 1GPTA 1NE5A 4AB0A 2LI7A 4UJ0A 1CHZA 1PE4A 1ICAA 1OMYA 1C55A 2KYQA 4AEIA 1JZBA 2I61A 2LR3A 2M8BB 2E3FA 1WT7A 1ZYWA 1NRAA 1JKZA 1I6GA 1VNAA 1ZUTA 1WWNA 1MYNA 4CQKA 1BRZA 1BCGA 1MR4A 2KBJA 2E3GA 1P0AA 4HE7A 2N2RA 1C56A
chains in the Genus database with same CATH superfamily
1TI5A 4H5RA 1FH3A 5AQFA 3L56A 2D56A 2QW9A 5AQXA 3QI7A 3C7NA 1ZYVA 1BK8A 2QWNA 1K8BA 2KBKA 1T7BA 1ATSA 3D2FB 4FL9A 2GL1A 2BRZA 2MN5A 5AQOA 2YIOA 2BUPA 4H5TA 1SN4A 3QFPA 1NGBA 1I2UA 2KPYA 1T1TA 1AHOA 1NGHA 1BRZA 3KVGA 1N4NA 4KBOA 1NGDA 2YILA 5AQPA 4HHFA 1LQQA 2MBKA 1T7EA 5F0XA 1PTXA 2LY6A 4H5NA 1QQNA 5AQQA 2E0HA 1ZVGA 1UGLA 2KSKA 2V7ZA 3KC6A 3KOYA 3CQXA 5F1XA 3JXUA 5AQKA 3ATUA 5EXWA 1BMRA 2E2FA 4V1DC 2G2KA 3L6QA 3FZLA 3LDLA 1I6FA 5BN8A 2LT8A 1LQHA 1CN2A 1B7DA 2LY5A 5KK4A 1BUPA 1DQ7A 1ZVEA 5AQMA 1GPSA 1KAZA 5AQNA 1NH5A 1T0ZA 1BA0A 1NPIA 4UAFE 2A7TA 5CY0A 1HJOA 1KAYA 2YEOA 5AQHA 3I33A 2KHOA 1OZZA 1ZFUA 2ASCA 1I2VA 3KHWA 2N2QA 5FPNA 1DJTA 2YC1C 3C7NB 3R2VA 1L4VA 1KV0A 5FPDA 1SNBA 1WMTA 3PSMA 1NGCA 1T7AA 2B68A 5AQRA 4HE7A 3L4IA 1DKGD 1YUWA 1B3CA 3LDOA 3AY9A 1NGJA 2KBHA 2QWLA 3FE1A 4H5WA 4KYPA 3LDPA 1XRSB 3D2EA 1PX9A 1VNBA 3KOWA 1JZAA 4AAZA 2LJ7A 1P00A 3FZMA 2JDQD 2NY8X 2QWMA 3LDNA 1NGEA 2ATBA 2LKBA 2N66A 2VY6A 2QXLA 3KOZA 5AQJA 5AQUA 1NGGA 3BK3C 2SN3A 4IO8A 5BPNA 1NGAA 3D2EB 1LQIA 5EX5A 2KJAA 1QQMA 3GDQA 2LN8A 5AQWA 1ZU3A 2N69A 2YIPA 1NRBA 1JXCA 2B3CA 2LJMA 3E7RL 3HSCA 5BPMA 1AYJA 3D2FA 1SN1A 2KGQA 2YBRC 3LDQA 1QQOA 2QWOA 5AQGA 2E88A 1SEGA 1ATRA 5AQIA 3SF4D 1NGIA 5BN9A 1KAXA 1POIA 2QWPA 3FZHA 3QFUA 4UADE 2E8AA 2NY9X 3CW4A 5AR0A 3E7UX 3QMLA 2MZ0A 3IUCA 1NGFA 4H5VA 2QWQA 1NE5A 1GPTA 1BA1A 1HPMA 2QWRA 5AQLA 3KP0A 4AB0A 2LI7A 3FZFA 4UJ0A 5EVZA 5AQSA 1CHZA 1PE4A 4GNIA 1ICAA 1OMYA 1C55A 1S3XA 2KYQA 3A8YA 5AQVA 1JZBA 2I61A 2LR3A 5EY4A 5AQZA 3KOXA 4AEIA 2M8BB 2GMOA 3FZKA 2E3FA 5FPEA 3GKUA 5AQTA 1WT7A 1ZYWA 1NRAA 5FPMA 1JKZA 3M3ZA 1I6GA 1VNAA 1ZUTA 1WWNA 3ATVA 1MYNA 4CQKA 4FSVA 5AQYA 5BPLA 1BCGA 4UAEF 1MR4A 2KBJA 1HX1A 2E3GA 1P0AA 2K35A 5F2RA 3GL1A 2N2RA 4HWIA 1C56A 3KP1A
chains in the Genus database with same CATH topology
1TI5A 1FH3A 1ZYVA 1BK8A 2KBKA 1T7BA 2GL1A 2BRZA 1SN4A 1I2UA 2KPYA 1T1TA 1AHOA 1N4NA 4HHFA 1LQQA 1T7EA 1PTXA 2LY6A 2E0HA 1ZVGA 2KSKA 1BMRA 4V1DC 1I6FA 2LT8A 1LQHA 1CN2A 1B7DA 2LY5A 5KK4A 1DQ7A 1ZVEA 1GPSA 1NH5A 1T0ZA 1NPIA 5CY0A 2A7TA 2YEOA 1OZZA 1ZFUA 2ASCA 1I2VA 2N2QA 1DJTA 2YC1C 1L4VA 1KV0A 1SNBA 1WMTA 3PSMA 1T7AA 2B68A 1B3CA 2KBHA 4KYPA 1PX9A 1VNBA 1JZAA 4AAZA 2LJ7A 1P00A 2NY8X 2ATBA 2LKBA 2N66A 2SN3A 1LQIA 2KJAA 1ZU3A 2N69A 1NRBA 1JXCA 2B3CA 2LJMA 3E7RL 1AYJA 1SN1A 2KGQA 2YBRC 1SEGA 2NY9X 3E7UX 2MZ0A 1GPTA 1NE5A 4AB0A 2LI7A 4UJ0A 1CHZA 1PE4A 1ICAA 1OMYA 1C55A 2KYQA 4AEIA 1JZBA 2I61A 2LR3A 2M8BB 2E3FA 1WT7A 1ZYWA 1NRAA 1JKZA 1I6GA 1VNAA 1ZUTA 1WWNA 1MYNA 4CQKA 1BRZA 1BCGA 1MR4A 2KBJA 2E3GA 1P0AA 4HE7A 2N2RA 1C56A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1TI5 A;  1FH3 A;  1ZYV A;  1BK8 A;  2KBK A;  1T7B A;  2GL1 A;  2BRZ A;  1SN4 A;  1I2U A;  2KPY A;  1T1T A;  1AHO A;  1N4N A;  4HHF A;  1LQQ A;  1T7E A;  1PTX A;  2LY6 A;  2E0H A;  1ZVG A;  2KSK A;  1BMR A;  4V1D C;  1I6F A;  2LT8 A;  1LQH A;  1CN2 A;  1B7D A;  2LY5 A;  5KK4 A;  1DQ7 A;  1ZVE A;  1GPS A;  1NH5 A;  1T0Z A;  1NPI A;  5CY0 A;  2A7T A;  2YEO A;  1OZZ A;  1ZFU A;  2ASC A;  1I2V A;  2N2Q A;  1DJT A;  2YC1 C;  1L4V A;  1KV0 A;  1SNB A;  1WMT A;  3PSM A;  1T7A A;  2B68 A;  1B3C A;  2KBH A;  4KYP A;  1PX9 A;  1VNB A;  1JZA A;  4AAZ A;  2LJ7 A;  1P00 A;  2NY8 X;  2ATB A;  2LKB A;  2N66 A;  2SN3 A;  1LQI A;  2KJA A;  1ZU3 A;  2N69 A;  1NRB A;  1JXC A;  2B3C A;  2LJM A;  3E7R L;  1AYJ A;  1SN1 A;  2KGQ A;  2YBR C;  1SEG A;  2NY9 X;  3E7U X;  2MZ0 A;  1GPT A;  1NE5 A;  4AB0 A;  2LI7 A;  4UJ0 A;  1CHZ A;  1PE4 A;  1ICA A;  1OMY A;  1C55 A;  2KYQ A;  4AEI A;  1JZB A;  2I61 A;  2LR3 A;  2M8B B;  2E3F A;  1WT7 A;  1ZYW A;  1NRA A;  1JKZ A;  1I6G A;  1VNA A;  1ZUT A;  1WWN A;  1MYN A;  4CQK A;  1BRZ A;  1BCG A;  1MR4 A;  2KBJ A;  2E3G A;  1P0A A;  4HE7 A;  2N2R A;  1C56 A; 
#chains in the Genus database with same CATH topology
 1TI5 A;  4H5R A;  1FH3 A;  5AQF A;  3L56 A;  2D56 A;  2QW9 A;  5AQX A;  3QI7 A;  3C7N A;  1ZYV A;  1BK8 A;  2QWN A;  1K8B A;  2KBK A;  1T7B A;  1ATS A;  3D2F B;  4FL9 A;  2GL1 A;  2BRZ A;  2MN5 A;  5AQO A;  2YIO A;  2BUP A;  4H5T A;  1SN4 A;  3QFP A;  1NGB A;  1I2U A;  2KPY A;  1T1T A;  1AHO A;  1NGH A;  1BRZ A;  3KVG A;  1N4N A;  4KBO A;  1NGD A;  2YIL A;  5AQP A;  4HHF A;  1LQQ A;  2MBK A;  1T7E A;  5F0X A;  1PTX A;  2LY6 A;  4H5N A;  1QQN A;  5AQQ A;  2E0H A;  1ZVG A;  1UGL A;  2KSK A;  2V7Z A;  3KC6 A;  3KOY A;  3CQX A;  5F1X A;  3JXU A;  5AQK A;  3ATU A;  5EXW A;  1BMR A;  2E2F A;  4V1D C;  2G2K A;  3L6Q A;  3FZL A;  3LDL A;  1I6F A;  5BN8 A;  2LT8 A;  1LQH A;  1CN2 A;  1B7D A;  2LY5 A;  5KK4 A;  1BUP A;  1DQ7 A;  1ZVE A;  5AQM A;  1GPS A;  1KAZ A;  5AQN A;  1NH5 A;  1T0Z A;  1BA0 A;  1NPI A;  4UAF E;  2A7T A;  5CY0 A;  1HJO A;  1KAY A;  2YEO A;  5AQH A;  3I33 A;  2KHO A;  1OZZ A;  1ZFU A;  2ASC A;  1I2V A;  3KHW A;  2N2Q A;  5FPN A;  1DJT A;  2YC1 C;  3C7N B;  3R2V A;  1L4V A;  1KV0 A;  5FPD A;  1SNB A;  1WMT A;  3PSM A;  1NGC A;  1T7A A;  2B68 A;  5AQR A;  4HE7 A;  3L4I A;  1DKG D;  1YUW A;  1B3C A;  3LDO A;  3AY9 A;  1NGJ A;  2KBH A;  2QWL A;  3FE1 A;  4H5W A;  4KYP A;  3LDP A;  1XRS B;  3D2E A;  1PX9 A;  1VNB A;  3KOW A;  1JZA A;  4AAZ A;  2LJ7 A;  1P00 A;  3FZM A;  2JDQ D;  2NY8 X;  2QWM A;  3LDN A;  1NGE A;  2ATB A;  2LKB A;  2N66 A;  2VY6 A;  2QXL A;  3KOZ A;  5AQJ A;  5AQU A;  1NGG A;  3BK3 C;  2SN3 A;  4IO8 A;  5BPN A;  1NGA A;  3D2E B;  1LQI A;  5EX5 A;  2KJA A;  1QQM A;  3GDQ A;  2LN8 A;  5AQW A;  1ZU3 A;  2N69 A;  2YIP A;  1NRB A;  1JXC A;  2B3C A;  2LJM A;  3E7R L;  3HSC A;  5BPM A;  1AYJ A;  3D2F A;  1SN1 A;  2KGQ A;  2YBR C;  3LDQ A;  1QQO A;  2QWO A;  5AQG A;  2E88 A;  1SEG A;  1ATR A;  5AQI A;  3SF4 D;  1NGI A;  5BN9 A;  1KAX A;  1POI A;  2QWP A;  3FZH A;  3QFU A;  4UAD E;  2E8A A;  2NY9 X;  3CW4 A;  5AR0 A;  3E7U X;  3QML A;  2MZ0 A;  3IUC A;  1NGF A;  4H5V A;  2QWQ A;  1NE5 A;  1GPT A;  1BA1 A;  1HPM A;  2QWR A;  5AQL A;  3KP0 A;  4AB0 A;  2LI7 A;  3FZF A;  4UJ0 A;  5EVZ A;  5AQS A;  1CHZ A;  1PE4 A;  4GNI A;  1ICA A;  1OMY A;  1C55 A;  1S3X A;  2KYQ A;  3A8Y A;  5AQV A;  1JZB A;  2I61 A;  2LR3 A;  5EY4 A;  5AQZ A;  3KOX A;  4AEI A;  2M8B B;  2GMO A;  3FZK A;  2E3F A;  5FPE A;  3GKU A;  5AQT A;  1WT7 A;  1ZYW A;  1NRA A;  5FPM A;  1JKZ A;  3M3Z A;  1I6G A;  1VNA A;  1ZUT A;  1WWN A;  3ATV A;  1MYN A;  4CQK A;  4FSV A;  5AQY A;  5BPL A;  1BCG A;  4UAE F;  1MR4 A;  2KBJ A;  1HX1 A;  2E3G A;  1P0A A;  2K35 A;  5F2R A;  3GL1 A;  2N2R A;  4HWI A;  1C56 A;  3KP1 A; 
#chains in the Genus database with same CATH homology
 1TI5 A;  1FH3 A;  1ZYV A;  1BK8 A;  2KBK A;  1T7B A;  2GL1 A;  2BRZ A;  1SN4 A;  1I2U A;  2KPY A;  1T1T A;  1AHO A;  1N4N A;  4HHF A;  1LQQ A;  1T7E A;  1PTX A;  2LY6 A;  2E0H A;  1ZVG A;  2KSK A;  1BMR A;  4V1D C;  1I6F A;  2LT8 A;  1LQH A;  1CN2 A;  1B7D A;  2LY5 A;  5KK4 A;  1DQ7 A;  1ZVE A;  1GPS A;  1NH5 A;  1T0Z A;  1NPI A;  5CY0 A;  2A7T A;  2YEO A;  1OZZ A;  1ZFU A;  2ASC A;  1I2V A;  2N2Q A;  1DJT A;  2YC1 C;  1L4V A;  1KV0 A;  1SNB A;  1WMT A;  3PSM A;  1T7A A;  2B68 A;  1B3C A;  2KBH A;  4KYP A;  1PX9 A;  1VNB A;  1JZA A;  4AAZ A;  2LJ7 A;  1P00 A;  2NY8 X;  2ATB A;  2LKB A;  2N66 A;  2SN3 A;  1LQI A;  2KJA A;  1ZU3 A;  2N69 A;  1NRB A;  1JXC A;  2B3C A;  2LJM A;  3E7R L;  1AYJ A;  1SN1 A;  2KGQ A;  2YBR C;  1SEG A;  2NY9 X;  3E7U X;  2MZ0 A;  1GPT A;  1NE5 A;  4AB0 A;  2LI7 A;  4UJ0 A;  1CHZ A;  1PE4 A;  1ICA A;  1OMY A;  1C55 A;  2KYQ A;  4AEI A;  1JZB A;  2I61 A;  2LR3 A;  2M8B B;  2E3F A;  1WT7 A;  1ZYW A;  1NRA A;  1JKZ A;  1I6G A;  1VNA A;  1ZUT A;  1WWN A;  1MYN A;  4CQK A;  1BRZ A;  1BCG A;  1MR4 A;  2KBJ A;  2E3G A;  1P0A A;  4HE7 A;  2N2R A;  1C56 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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