1I2UA

Nmr solution structures of antifungal heliomicin
Total Genus 11
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
11
sequence length
44
structure length
44
Chain Sequence
DKLIGSCVWGAVNYTSDCNGECKRRGYKGGHCGSFANVNCWCET
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Solution structures of the antifungal heliomicin and a selected variant with both antibacterial and antifungal activities.
pubmed doi rcsb
molecule tags Antifungal protein
source organism Heliothis virescens
molecule keywords DEFENSIN HELIOMICIN
total genus 11
structure length 44
sequence length 44
ec nomenclature
pdb deposition date 2001-02-12
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.30.10 Alpha Beta 2-Layer Sandwich Defensin A-like Knottin, scorpion toxin-like 1i2uA00
2E0HA 1SN4A 1T1TA 1B3CA 1AHOA 2LJMA 1JZBA 1ICAA 1DJTA 1OZZA 1TI5A 2N69A 1ZVGA 1GPSA 1SN1A 2M8BB 1WWNA 1WMTA 2KJAA 2YC1C 1MR4A 2LY5A 4HE7A 1T0ZA 2KYQA 2KBHA 2YBRC 1JKZA 1I2UA 2LR3A 2YEOA 1CHZA 2SN3A 1N4NA 2ATBA 2NY8X 1SEGA 4CQKA 1P00A 2KSKA 1JZAA 1ZFUA 4AEIA 1L4VA 1NH5A 2LT8A 1CN2A 1NRBA 1BK8A 1T7EA 2I61A 1LQIA 2LI7A 2B3CA 1I2VA 4KYPA 1ZUTA 1BCGA 1VNBA 4AB0A 2E3GA 1LQQA 2GL1A 2LKBA 2N2RA 1ZVEA 1BMRA 2ASCA 1AYJA 1NE5A 3E7RL 2MZ0A 2A7TA 5KK4A 2KGQA 4HHFA 2N66A 1ZU3A 1JXCA 1NPIA 4V1DC 1FH3A 1B7DA 1GPTA 2LJ7A 2N2QA 1OMYA 1KV0A 1PTXA 1NRAA 5CY0A 2B68A 1T7AA 4AAZA 3PSMA 1I6GA 2E3FA 1WT7A 3E7UX 1C56A 2BRZA 1PE4A 1BRZA 1C55A 1P0AA 2NY9X 1DQ7A 1VNAA 1ZYWA 1SNBA 2KBJA 2KBKA 1I6FA 2LY6A 1MYNA 4UJ0A 2KPYA 1T7BA 1ZYVA 1PX9A 1LQHA
chains in the Genus database with same CATH superfamily
3LDLA 3KOYA 1KAYA 2E0HA 2YILA 3D2FB 4UAFE 1SN4A 1T1TA 1B3CA 3LDPA 5EXWA 1NGHA 1AHOA 2LJMA 3KP0A 3LDNA 1JZBA 1ICAA 5FPMA 5BPLA 3FZFA 1KAXA 1DJTA 4H5VA 4IO8A 1OZZA 1TI5A 3A8YA 2N69A 1ZVGA 2V7ZA 1GPSA 5AQPA 1SN1A 3GL1A 2M8BB 2YIPA 3KOWA 4GNIA 1WWNA 1WMTA 2KJAA 4H5RA 4KBOA 2YC1C 1MR4A 2LY5A 4H5TA 4HE7A 1T0ZA 2KYQA 1HPMA 2QWOA 2KBHA 2YBRC 3QI7A 3R2VA 2LR3A 4FSVA 2YEOA 1JKZA 3D2EA 3FZKA 1CHZA 2MBKA 1I2UA 1NGGA 2SN3A 1N4NA 1BUPA 2ATBA 3D2FA 2JDQD 3QFPA 1KAZA 2YIOA 3LDQA 3KHWA 2BUPA 1SEGA 2NY8X 4CQKA 3D2EB 1UGLA 5EX5A 2QWNA 1P00A 2KSKA 3KC6A 3I33A 1JZAA 1ZFUA 3FZHA 4AEIA 2K35A 3QMLA 1NH5A 1L4VA 3M3ZA 2LT8A 3CQXA 1CN2A 2G2KA 2QWMA 1NRBA 1QQOA 1BK8A 1T7EA 5AQUA 5AQYA 2I61A 1LQIA 5AQLA 5AQVA 1QQNA 2LI7A 2B3CA 1ZYVA 2E2FA 1I2VA 4KYPA 1BA0A 1ZUTA 1BCGA 1VNBA 4AB0A 3KOZA 2E3GA 1LQQA 2GL1A 5AQJA 2LKBA 2N2RA 1ZVEA 5AQOA 1BMRA 2ASCA 2E8AA 5AQNA 1AYJA 1NE5A 3E7RL 5AQFA 2MZ0A 3CW4A 4H5WA 2A7TA 5FPEA 5F0XA 2KGQA 5KK4A 1K8BA 2QWPA 5AQQA 5BN8A 4HHFA 1QQMA 2N66A 3FZMA 4UAEF 1ZU3A 2D56A 3C7NB 3FE1A 1JXCA 5AQHA 5AQZA 1NPIA 3SF4D 5AR0A 5AQIA 2MN5A 3IUCA 4V1DC 4H5NA 5EY4A 1FH3A 1B7DA 1YUWA 1GPTA 3L4IA 2LJ7A 5BPNA 5AQWA 2N2QA 3AY9A 2QWRA 5FPNA 3KOXA 1OMYA 1HJOA 1KV0A 1PTXA 3GDQA 1XRSB 1NRAA 5AQXA 1DKGD 5FPDA 5AQTA 2GMOA 5CY0A 2B68A 3ATVA 3LDOA 1T7AA 1NGAA 2QWQA 4AAZA 3PSMA 5AQSA 5AQKA 3C7NA 1I6GA 3HSCA 2E3FA 1NGDA 1WT7A 2E88A 5AQGA 5AQRA 5F2RA 4FL9A 3ATUA 3FZLA 3E7UX 1C56A 2BRZA 1BA1A 5BPMA 1NGIA 2LN8A 4HWIA 3KVGA 3L56A 1PE4A 1BRZA 1ATRA 3QFUA 1C55A 1ATSA 1P0AA 2NY9X 1POIA 4UADE 1DQ7A 1VNAA 1ZYWA 2VY6A 5BN9A 1HX1A 1SNBA 2KBJA 3GKUA 1NGCA 1NGBA 5EVZA 3BK3C 2QW9A 3JXUA 2KBKA 2QXLA 1I6FA 2LY6A 1S3XA 5F1XA 1MYNA 5AQMA 4UJ0A 2KHOA 2QWLA 2KPYA 1NGFA 1T7BA 1NGJA 3KP1A 1PX9A 1LQHA 3L6QA 1NGEA
chains in the Genus database with same CATH topology
2E0HA 1SN4A 1T1TA 1B3CA 1AHOA 2LJMA 1JZBA 1ICAA 1DJTA 1OZZA 1TI5A 2N69A 1ZVGA 1GPSA 1SN1A 2M8BB 1WWNA 1WMTA 2KJAA 2YC1C 1MR4A 2LY5A 4HE7A 1T0ZA 2KYQA 2KBHA 2YBRC 1JKZA 1I2UA 2LR3A 2YEOA 1CHZA 2SN3A 1N4NA 2ATBA 2NY8X 1SEGA 4CQKA 1P00A 2KSKA 1JZAA 1ZFUA 4AEIA 1L4VA 1NH5A 2LT8A 1CN2A 1NRBA 1BK8A 1T7EA 2I61A 1LQIA 2LI7A 2B3CA 1I2VA 4KYPA 1ZUTA 1BCGA 1VNBA 4AB0A 2E3GA 1LQQA 2GL1A 2LKBA 2N2RA 1ZVEA 1BMRA 2ASCA 1AYJA 1NE5A 3E7RL 2MZ0A 2A7TA 5KK4A 2KGQA 4HHFA 2N66A 1ZU3A 1JXCA 1NPIA 4V1DC 1FH3A 1B7DA 1GPTA 2LJ7A 2N2QA 1OMYA 1KV0A 1PTXA 1NRAA 5CY0A 2B68A 1T7AA 4AAZA 3PSMA 1I6GA 2E3FA 1WT7A 3E7UX 1C56A 2BRZA 1PE4A 1BRZA 1C55A 1P0AA 2NY9X 1DQ7A 1VNAA 1ZYWA 1SNBA 2KBJA 2KBKA 1I6FA 2LY6A 1MYNA 4UJ0A 2KPYA 1T7BA 1ZYVA 1PX9A 1LQHA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2E0H A;  1SN4 A;  1T1T A;  1B3C A;  1AHO A;  2LJM A;  1JZB A;  1ICA A;  1DJT A;  1OZZ A;  1TI5 A;  2N69 A;  1ZVG A;  1GPS A;  1SN1 A;  2M8B B;  1WWN A;  1WMT A;  2KJA A;  2YC1 C;  1MR4 A;  2LY5 A;  4HE7 A;  1T0Z A;  2KYQ A;  2KBH A;  2YBR C;  1JKZ A;  1I2U A;  2LR3 A;  2YEO A;  1CHZ A;  2SN3 A;  1N4N A;  2ATB A;  2NY8 X;  1SEG A;  4CQK A;  1P00 A;  2KSK A;  1JZA A;  1ZFU A;  4AEI A;  1L4V A;  1NH5 A;  2LT8 A;  1CN2 A;  1NRB A;  1BK8 A;  1T7E A;  2I61 A;  1LQI A;  2LI7 A;  2B3C A;  1I2V A;  4KYP A;  1ZUT A;  1BCG A;  1VNB A;  4AB0 A;  2E3G A;  1LQQ A;  2GL1 A;  2LKB A;  2N2R A;  1ZVE A;  1BMR A;  2ASC A;  1AYJ A;  1NE5 A;  3E7R L;  2MZ0 A;  2A7T A;  5KK4 A;  2KGQ A;  4HHF A;  2N66 A;  1ZU3 A;  1JXC A;  1NPI A;  4V1D C;  1FH3 A;  1B7D A;  1GPT A;  2LJ7 A;  2N2Q A;  1OMY A;  1KV0 A;  1PTX A;  1NRA A;  5CY0 A;  2B68 A;  1T7A A;  4AAZ A;  3PSM A;  1I6G A;  2E3F A;  1WT7 A;  3E7U X;  1C56 A;  2BRZ A;  1PE4 A;  1BRZ A;  1C55 A;  1P0A A;  2NY9 X;  1DQ7 A;  1VNA A;  1ZYW A;  1SNB A;  2KBJ A;  2KBK A;  1I6F A;  2LY6 A;  1MYN A;  4UJ0 A;  2KPY A;  1T7B A;  1ZYV A;  1PX9 A;  1LQH A; 
#chains in the Genus database with same CATH topology
 3LDL A;  3KOY A;  1KAY A;  2E0H A;  2YIL A;  3D2F B;  4UAF E;  1SN4 A;  1T1T A;  1B3C A;  3LDP A;  5EXW A;  1NGH A;  1AHO A;  2LJM A;  3KP0 A;  3LDN A;  1JZB A;  1ICA A;  5FPM A;  5BPL A;  3FZF A;  1KAX A;  1DJT A;  4H5V A;  4IO8 A;  1OZZ A;  1TI5 A;  3A8Y A;  2N69 A;  1ZVG A;  2V7Z A;  1GPS A;  5AQP A;  1SN1 A;  3GL1 A;  2M8B B;  2YIP A;  3KOW A;  4GNI A;  1WWN A;  1WMT A;  2KJA A;  4H5R A;  4KBO A;  2YC1 C;  1MR4 A;  2LY5 A;  4H5T A;  4HE7 A;  1T0Z A;  2KYQ A;  1HPM A;  2QWO A;  2KBH A;  2YBR C;  3QI7 A;  3R2V A;  2LR3 A;  4FSV A;  2YEO A;  1JKZ A;  3D2E A;  3FZK A;  1CHZ A;  2MBK A;  1I2U A;  1NGG A;  2SN3 A;  1N4N A;  1BUP A;  2ATB A;  3D2F A;  2JDQ D;  3QFP A;  1KAZ A;  2YIO A;  3LDQ A;  3KHW A;  2BUP A;  1SEG A;  2NY8 X;  4CQK A;  3D2E B;  1UGL A;  5EX5 A;  2QWN A;  1P00 A;  2KSK A;  3KC6 A;  3I33 A;  1JZA A;  1ZFU A;  3FZH A;  4AEI A;  2K35 A;  3QML A;  1NH5 A;  1L4V A;  3M3Z A;  2LT8 A;  3CQX A;  1CN2 A;  2G2K A;  2QWM A;  1NRB A;  1QQO A;  1BK8 A;  1T7E A;  5AQU A;  5AQY A;  2I61 A;  1LQI A;  5AQL A;  5AQV A;  1QQN A;  2LI7 A;  2B3C A;  1ZYV A;  2E2F A;  1I2V A;  4KYP A;  1BA0 A;  1ZUT A;  1BCG A;  1VNB A;  4AB0 A;  3KOZ A;  2E3G A;  1LQQ A;  2GL1 A;  5AQJ A;  2LKB A;  2N2R A;  1ZVE A;  5AQO A;  1BMR A;  2ASC A;  2E8A A;  5AQN A;  1AYJ A;  1NE5 A;  3E7R L;  5AQF A;  2MZ0 A;  3CW4 A;  4H5W A;  2A7T A;  5FPE A;  5F0X A;  2KGQ A;  5KK4 A;  1K8B A;  2QWP A;  5AQQ A;  5BN8 A;  4HHF A;  1QQM A;  2N66 A;  3FZM A;  4UAE F;  1ZU3 A;  2D56 A;  3C7N B;  3FE1 A;  1JXC A;  5AQH A;  5AQZ A;  1NPI A;  3SF4 D;  5AR0 A;  5AQI A;  2MN5 A;  3IUC A;  4V1D C;  4H5N A;  5EY4 A;  1FH3 A;  1B7D A;  1YUW A;  1GPT A;  3L4I A;  2LJ7 A;  5BPN A;  5AQW A;  2N2Q A;  3AY9 A;  2QWR A;  5FPN A;  3KOX A;  1OMY A;  1HJO A;  1KV0 A;  1PTX A;  3GDQ A;  1XRS B;  1NRA A;  5AQX A;  1DKG D;  5FPD A;  5AQT A;  2GMO A;  5CY0 A;  2B68 A;  3ATV A;  3LDO A;  1T7A A;  1NGA A;  2QWQ A;  4AAZ A;  3PSM A;  5AQS A;  5AQK A;  3C7N A;  1I6G A;  3HSC A;  2E3F A;  1NGD A;  1WT7 A;  2E88 A;  5AQG A;  5AQR A;  5F2R A;  4FL9 A;  3ATU A;  3FZL A;  3E7U X;  1C56 A;  2BRZ A;  1BA1 A;  5BPM A;  1NGI A;  2LN8 A;  4HWI A;  3KVG A;  3L56 A;  1PE4 A;  1BRZ A;  1ATR A;  3QFU A;  1C55 A;  1ATS A;  1P0A A;  2NY9 X;  1POI A;  4UAD E;  1DQ7 A;  1VNA A;  1ZYW A;  2VY6 A;  5BN9 A;  1HX1 A;  1SNB A;  2KBJ A;  3GKU A;  1NGC A;  1NGB A;  5EVZ A;  3BK3 C;  2QW9 A;  3JXU A;  2KBK A;  2QXL A;  1I6F A;  2LY6 A;  1S3X A;  5F1X A;  1MYN A;  5AQM A;  4UJ0 A;  2KHO A;  2QWL A;  2KPY A;  1NGF A;  1T7B A;  1NGJ A;  3KP1 A;  1PX9 A;  1LQH A;  3L6Q A;  1NGE A; 
#chains in the Genus database with same CATH homology
 2E0H A;  1SN4 A;  1T1T A;  1B3C A;  1AHO A;  2LJM A;  1JZB A;  1ICA A;  1DJT A;  1OZZ A;  1TI5 A;  2N69 A;  1ZVG A;  1GPS A;  1SN1 A;  2M8B B;  1WWN A;  1WMT A;  2KJA A;  2YC1 C;  1MR4 A;  2LY5 A;  4HE7 A;  1T0Z A;  2KYQ A;  2KBH A;  2YBR C;  1JKZ A;  1I2U A;  2LR3 A;  2YEO A;  1CHZ A;  2SN3 A;  1N4N A;  2ATB A;  2NY8 X;  1SEG A;  4CQK A;  1P00 A;  2KSK A;  1JZA A;  1ZFU A;  4AEI A;  1L4V A;  1NH5 A;  2LT8 A;  1CN2 A;  1NRB A;  1BK8 A;  1T7E A;  2I61 A;  1LQI A;  2LI7 A;  2B3C A;  1I2V A;  4KYP A;  1ZUT A;  1BCG A;  1VNB A;  4AB0 A;  2E3G A;  1LQQ A;  2GL1 A;  2LKB A;  2N2R A;  1ZVE A;  1BMR A;  2ASC A;  1AYJ A;  1NE5 A;  3E7R L;  2MZ0 A;  2A7T A;  5KK4 A;  2KGQ A;  4HHF A;  2N66 A;  1ZU3 A;  1JXC A;  1NPI A;  4V1D C;  1FH3 A;  1B7D A;  1GPT A;  2LJ7 A;  2N2Q A;  1OMY A;  1KV0 A;  1PTX A;  1NRA A;  5CY0 A;  2B68 A;  1T7A A;  4AAZ A;  3PSM A;  1I6G A;  2E3F A;  1WT7 A;  3E7U X;  1C56 A;  2BRZ A;  1PE4 A;  1BRZ A;  1C55 A;  1P0A A;  2NY9 X;  1DQ7 A;  1VNA A;  1ZYW A;  1SNB A;  2KBJ A;  2KBK A;  1I6F A;  2LY6 A;  1MYN A;  4UJ0 A;  2KPY A;  1T7B A;  1ZYV A;  1PX9 A;  1LQH A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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