1I6GA

Nmr solution structure of the insect-specific neurotoxin variant 5 (cse-v5) from the scorpion centruroides sculpturatus ewing
Total Genus 10
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
10
sequence length
60
structure length
60
Chain Sequence
KDGYPVDSKGCKLSCVANNYCDNQCKMKKASGGHCYAMSCYCEGLPENAKVSDSATNICG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Toxin
publication title Solution structure of an insect-specific neurotoxin from the New World scorpion Centruroides sculpturatus Ewing.
pubmed doi rcsb
molecule keywords NEUROTOXIN V-5
total genus 10
structure length 60
sequence length 60
ec nomenclature
pdb deposition date 2001-03-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00537 Toxin_3 Scorpion toxin-like domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.30.10 Alpha Beta 2-Layer Sandwich Defensin A-like Knottin, scorpion toxin-like 1i6gA00
2N2RA 1T0ZA 2NY9X 1T7BA 1AHOA 1NE5A 2GL1A 1PTXA 2KSKA 2SN3A 3E7RL 1BRZA 2B68A 4KYPA 2BRZA 1AYJA 1NRBA 5CY0A 2KBHA 2E3FA 1ZUTA 1JXCA 2LR3A 1OZZA 4HHFA 1NH5A 1OMYA 1C56A 2KBKA 2KPYA 1LQQA 1ZVGA 1KV0A 1ZYWA 1P0AA 2NY8X 1SN1A 1T7EA 4AB0A 2N2QA 2LJMA 1FH3A 1LQHA 2N69A 1ZVEA 1WT7A 2LY5A 1DQ7A 3E7UX 1JKZA 1MR4A 1L4VA 2LI7A 1PX9A 2KGQA 1ZFUA 1TI5A 2LJ7A 1CN2A 1B7DA 1VNAA 2YC1C 4HE7A 2E3GA 2KJAA 2ATBA 1SNBA 2M8BB 1WWNA 2YEOA 1MYNA 1GPTA 1SN4A 1B3CA 4V1DC 1NRAA 1P00A 1SEGA 3PSMA 5KK4A 1ICAA 1VNBA 1JZBA 2I61A 1DJTA 1I2VA 1I2UA 2LY6A 2N66A 1ZU3A 1I6FA 2LKBA 2MZ0A 2LT8A 1ZYVA 1CHZA 1BK8A 1PE4A 2KBJA 2A7TA 1GPSA 2E0HA 1T7AA 1I6GA 1NPIA 1N4NA 1BCGA 4UJ0A 4AEIA 4AAZA 2ASCA 1BMRA 2B3CA 1C55A 1T1TA 4CQKA 1JZAA 1WMTA 2YBRC 2KYQA 1LQIA
chains in the Genus database with same CATH superfamily
1S3XA 5AQZA 2QWLA 2N2RA 3BK3C 1T0ZA 2NY9X 1T7BA 1AHOA 5BPNA 3LDQA 1KAYA 1NE5A 1HPMA 2GL1A 1PTXA 2KSKA 3KHWA 3LDPA 2E2FA 2SN3A 3E7RL 3GDQA 3KVGA 3A8YA 2K35A 1KAZA 3QFUA 4FSVA 3QMLA 5AQJA 1BRZA 5AQNA 2B68A 3QFPA 2BRZA 3KP1A 3L4IA 4KYPA 5FPNA 3CW4A 2QWRA 5EY4A 1AYJA 1NRBA 5CY0A 2KBHA 3FZFA 1QQOA 2E3FA 1ZUTA 3GKUA 1JXCA 1K8BA 5F2RA 2LR3A 3ATVA 5AQWA 1OZZA 4HHFA 1NH5A 3FE1A 1OMYA 1C56A 3LDOA 2E8AA 2KBKA 2GMOA 1UGLA 2BUPA 3FZLA 4H5WA 5EVZA 1HX1A 2G2KA 2KPYA 1LQQA 1ZVGA 1KV0A 3D2EA 1ZYWA 1P0AA 2NY8X 4H5VA 4KBOA 4UADE 5AQLA 1SN1A 1T7EA 4UAEF 4AB0A 2N2QA 3FZMA 2LJMA 3KC6A 1NGEA 1FH3A 2V7ZA 1LQHA 2N69A 1ZVEA 5AQUA 5AQMA 3D2FA 5AQHA 3KOYA 1WT7A 2QXLA 5BPLA 1XRSB 2LY5A 1DQ7A 3E7UX 1JKZA 1MR4A 1L4VA 2LI7A 4HWIA 3HSCA 1PX9A 2KGQA 3L56A 2KHOA 1ZFUA 2YIOA 1TI5A 2LJ7A 1POIA 1CN2A 3GL1A 3KP0A 1B7DA 2YIPA 1VNAA 2E88A 2YC1C 3D2FB 3JXUA 1NGAA 4HE7A 4FL9A 5AQXA 1NGGA 2E3GA 5AQRA 2KJAA 2ATBA 1SNBA 2D56A 2M8BB 2YEOA 3LDLA 5AQOA 1MYNA 2QWPA 5AQGA 1GPTA 1NGFA 1SN4A 3IUCA 5FPEA 1NGCA 2JDQD 3SF4D 1BA1A 1ATRA 5AQTA 1B3CA 2QWQA 1NGBA 4V1DC 1NRAA 3CQXA 1P00A 1SEGA 3PSMA 5KK4A 5AQYA 3L6QA 3FZKA 1ICAA 1VNBA 5AQIA 1KAXA 1JZBA 4H5TA 5AQVA 1NGDA 2I61A 3D2EB 3C7NA 4IO8A 2VY6A 1DJTA 1HJOA 2MBKA 5BPMA 1I2VA 1I2UA 2LY6A 1NGHA 1BUPA 4H5NA 2N66A 5F0XA 1QQNA 3R2VA 5AQSA 1ZU3A 1I6FA 1NGIA 2LKBA 2MZ0A 2LT8A 3AY9A 5FPMA 5BN9A 1ZYVA 2LN8A 1CHZA 1BK8A 2YBRC 3C7NB 1PE4A 5EX5A 5FPDA 3FZHA 2KBJA 2A7TA 4H5RA 1GPSA 2E0HA 2QWMA 1DKGD 3KOZA 3KOXA 4GNIA 5F1XA 1T7AA 3ATUA 1I6GA 3I33A 1NPIA 5AQKA 3QI7A 5EXWA 1YUWA 1N4NA 2KYQA 2QW9A 1BCGA 4UJ0A 2YILA 4AEIA 4AAZA 2ASCA 2MN5A 3M3ZA 5AQQA 1BMRA 5AQFA 2B3CA 1C55A 3KOWA 1T1TA 4CQKA 1ATSA 3LDNA 1QQMA 5BN8A 1JZAA 5AR0A 1WMTA 4UAFE 1BA0A 2QWNA 2QWOA 5AQPA 1NGJA 1WWNA 1LQIA
chains in the Genus database with same CATH topology
2N2RA 1T0ZA 2NY9X 1T7BA 1AHOA 1NE5A 2GL1A 1PTXA 2KSKA 2SN3A 3E7RL 1BRZA 2B68A 4KYPA 2BRZA 1AYJA 1NRBA 5CY0A 2KBHA 2E3FA 1ZUTA 1JXCA 2LR3A 1OZZA 4HHFA 1NH5A 1OMYA 1C56A 2KBKA 2KPYA 1LQQA 1ZVGA 1KV0A 1ZYWA 1P0AA 2NY8X 1SN1A 1T7EA 4AB0A 2N2QA 2LJMA 1FH3A 1LQHA 2N69A 1ZVEA 1WT7A 2LY5A 1DQ7A 3E7UX 1JKZA 1MR4A 1L4VA 2LI7A 1PX9A 2KGQA 1ZFUA 1TI5A 2LJ7A 1CN2A 1B7DA 1VNAA 2YC1C 4HE7A 2E3GA 2KJAA 2ATBA 1SNBA 2M8BB 1WWNA 2YEOA 1MYNA 1GPTA 1SN4A 1B3CA 4V1DC 1NRAA 1P00A 1SEGA 3PSMA 5KK4A 1ICAA 1VNBA 1JZBA 2I61A 1DJTA 1I2VA 1I2UA 2LY6A 2N66A 1ZU3A 1I6FA 2LKBA 2MZ0A 2LT8A 1ZYVA 1CHZA 1BK8A 1PE4A 2KBJA 2A7TA 1GPSA 2E0HA 1T7AA 1I6GA 1NPIA 1N4NA 1BCGA 4UJ0A 4AEIA 4AAZA 2ASCA 1BMRA 2B3CA 1C55A 1T1TA 4CQKA 1JZAA 1WMTA 2YBRC 2KYQA 1LQIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2N2R A;  1T0Z A;  2NY9 X;  1T7B A;  1AHO A;  1NE5 A;  2GL1 A;  1PTX A;  2KSK A;  2SN3 A;  3E7R L;  1BRZ A;  2B68 A;  4KYP A;  2BRZ A;  1AYJ A;  1NRB A;  5CY0 A;  2KBH A;  2E3F A;  1ZUT A;  1JXC A;  2LR3 A;  1OZZ A;  4HHF A;  1NH5 A;  1OMY A;  1C56 A;  2KBK A;  2KPY A;  1LQQ A;  1ZVG A;  1KV0 A;  1ZYW A;  1P0A A;  2NY8 X;  1SN1 A;  1T7E A;  4AB0 A;  2N2Q A;  2LJM A;  1FH3 A;  1LQH A;  2N69 A;  1ZVE A;  1WT7 A;  2LY5 A;  1DQ7 A;  3E7U X;  1JKZ A;  1MR4 A;  1L4V A;  2LI7 A;  1PX9 A;  2KGQ A;  1ZFU A;  1TI5 A;  2LJ7 A;  1CN2 A;  1B7D A;  1VNA A;  2YC1 C;  4HE7 A;  2E3G A;  2KJA A;  2ATB A;  1SNB A;  2M8B B;  1WWN A;  2YEO A;  1MYN A;  1GPT A;  1SN4 A;  1B3C A;  4V1D C;  1NRA A;  1P00 A;  1SEG A;  3PSM A;  5KK4 A;  1ICA A;  1VNB A;  1JZB A;  2I61 A;  1DJT A;  1I2V A;  1I2U A;  2LY6 A;  2N66 A;  1ZU3 A;  1I6F A;  2LKB A;  2MZ0 A;  2LT8 A;  1ZYV A;  1CHZ A;  1BK8 A;  1PE4 A;  2KBJ A;  2A7T A;  1GPS A;  2E0H A;  1T7A A;  1I6G A;  1NPI A;  1N4N A;  1BCG A;  4UJ0 A;  4AEI A;  4AAZ A;  2ASC A;  1BMR A;  2B3C A;  1C55 A;  1T1T A;  4CQK A;  1JZA A;  1WMT A;  2YBR C;  2KYQ A;  1LQI A; 
#chains in the Genus database with same CATH topology
 1S3X A;  5AQZ A;  2QWL A;  2N2R A;  3BK3 C;  1T0Z A;  2NY9 X;  1T7B A;  1AHO A;  5BPN A;  3LDQ A;  1KAY A;  1NE5 A;  1HPM A;  2GL1 A;  1PTX A;  2KSK A;  3KHW A;  3LDP A;  2E2F A;  2SN3 A;  3E7R L;  3GDQ A;  3KVG A;  3A8Y A;  2K35 A;  1KAZ A;  3QFU A;  4FSV A;  3QML A;  5AQJ A;  1BRZ A;  5AQN A;  2B68 A;  3QFP A;  2BRZ A;  3KP1 A;  3L4I A;  4KYP A;  5FPN A;  3CW4 A;  2QWR A;  5EY4 A;  1AYJ A;  1NRB A;  5CY0 A;  2KBH A;  3FZF A;  1QQO A;  2E3F A;  1ZUT A;  3GKU A;  1JXC A;  1K8B A;  5F2R A;  2LR3 A;  3ATV A;  5AQW A;  1OZZ A;  4HHF A;  1NH5 A;  3FE1 A;  1OMY A;  1C56 A;  3LDO A;  2E8A A;  2KBK A;  2GMO A;  1UGL A;  2BUP A;  3FZL A;  4H5W A;  5EVZ A;  1HX1 A;  2G2K A;  2KPY A;  1LQQ A;  1ZVG A;  1KV0 A;  3D2E A;  1ZYW A;  1P0A A;  2NY8 X;  4H5V A;  4KBO A;  4UAD E;  5AQL A;  1SN1 A;  1T7E A;  4UAE F;  4AB0 A;  2N2Q A;  3FZM A;  2LJM A;  3KC6 A;  1NGE A;  1FH3 A;  2V7Z A;  1LQH A;  2N69 A;  1ZVE A;  5AQU A;  5AQM A;  3D2F A;  5AQH A;  3KOY A;  1WT7 A;  2QXL A;  5BPL A;  1XRS B;  2LY5 A;  1DQ7 A;  3E7U X;  1JKZ A;  1MR4 A;  1L4V A;  2LI7 A;  4HWI A;  3HSC A;  1PX9 A;  2KGQ A;  3L56 A;  2KHO A;  1ZFU A;  2YIO A;  1TI5 A;  2LJ7 A;  1POI A;  1CN2 A;  3GL1 A;  3KP0 A;  1B7D A;  2YIP A;  1VNA A;  2E88 A;  2YC1 C;  3D2F B;  3JXU A;  1NGA A;  4HE7 A;  4FL9 A;  5AQX A;  1NGG A;  2E3G A;  5AQR A;  2KJA A;  2ATB A;  1SNB A;  2D56 A;  2M8B B;  2YEO A;  3LDL A;  5AQO A;  1MYN A;  2QWP A;  5AQG A;  1GPT A;  1NGF A;  1SN4 A;  3IUC A;  5FPE A;  1NGC A;  2JDQ D;  3SF4 D;  1BA1 A;  1ATR A;  5AQT A;  1B3C A;  2QWQ A;  1NGB A;  4V1D C;  1NRA A;  3CQX A;  1P00 A;  1SEG A;  3PSM A;  5KK4 A;  5AQY A;  3L6Q A;  3FZK A;  1ICA A;  1VNB A;  5AQI A;  1KAX A;  1JZB A;  4H5T A;  5AQV A;  1NGD A;  2I61 A;  3D2E B;  3C7N A;  4IO8 A;  2VY6 A;  1DJT A;  1HJO A;  2MBK A;  5BPM A;  1I2V A;  1I2U A;  2LY6 A;  1NGH A;  1BUP A;  4H5N A;  2N66 A;  5F0X A;  1QQN A;  3R2V A;  5AQS A;  1ZU3 A;  1I6F A;  1NGI A;  2LKB A;  2MZ0 A;  2LT8 A;  3AY9 A;  5FPM A;  5BN9 A;  1ZYV A;  2LN8 A;  1CHZ A;  1BK8 A;  2YBR C;  3C7N B;  1PE4 A;  5EX5 A;  5FPD A;  3FZH A;  2KBJ A;  2A7T A;  4H5R A;  1GPS A;  2E0H A;  2QWM A;  1DKG D;  3KOZ A;  3KOX A;  4GNI A;  5F1X A;  1T7A A;  3ATU A;  1I6G A;  3I33 A;  1NPI A;  5AQK A;  3QI7 A;  5EXW A;  1YUW A;  1N4N A;  2KYQ A;  2QW9 A;  1BCG A;  4UJ0 A;  2YIL A;  4AEI A;  4AAZ A;  2ASC A;  2MN5 A;  3M3Z A;  5AQQ A;  1BMR A;  5AQF A;  2B3C A;  1C55 A;  3KOW A;  1T1T A;  4CQK A;  1ATS A;  3LDN A;  1QQM A;  5BN8 A;  1JZA A;  5AR0 A;  1WMT A;  4UAF E;  1BA0 A;  2QWN A;  2QWO A;  5AQP A;  1NGJ A;  1WWN A;  1LQI A; 
#chains in the Genus database with same CATH homology
 2N2R A;  1T0Z A;  2NY9 X;  1T7B A;  1AHO A;  1NE5 A;  2GL1 A;  1PTX A;  2KSK A;  2SN3 A;  3E7R L;  1BRZ A;  2B68 A;  4KYP A;  2BRZ A;  1AYJ A;  1NRB A;  5CY0 A;  2KBH A;  2E3F A;  1ZUT A;  1JXC A;  2LR3 A;  1OZZ A;  4HHF A;  1NH5 A;  1OMY A;  1C56 A;  2KBK A;  2KPY A;  1LQQ A;  1ZVG A;  1KV0 A;  1ZYW A;  1P0A A;  2NY8 X;  1SN1 A;  1T7E A;  4AB0 A;  2N2Q A;  2LJM A;  1FH3 A;  1LQH A;  2N69 A;  1ZVE A;  1WT7 A;  2LY5 A;  1DQ7 A;  3E7U X;  1JKZ A;  1MR4 A;  1L4V A;  2LI7 A;  1PX9 A;  2KGQ A;  1ZFU A;  1TI5 A;  2LJ7 A;  1CN2 A;  1B7D A;  1VNA A;  2YC1 C;  4HE7 A;  2E3G A;  2KJA A;  2ATB A;  1SNB A;  2M8B B;  1WWN A;  2YEO A;  1MYN A;  1GPT A;  1SN4 A;  1B3C A;  4V1D C;  1NRA A;  1P00 A;  1SEG A;  3PSM A;  5KK4 A;  1ICA A;  1VNB A;  1JZB A;  2I61 A;  1DJT A;  1I2V A;  1I2U A;  2LY6 A;  2N66 A;  1ZU3 A;  1I6F A;  2LKB A;  2MZ0 A;  2LT8 A;  1ZYV A;  1CHZ A;  1BK8 A;  1PE4 A;  2KBJ A;  2A7T A;  1GPS A;  2E0H A;  1T7A A;  1I6G A;  1NPI A;  1N4N A;  1BCG A;  4UJ0 A;  4AEI A;  4AAZ A;  2ASC A;  1BMR A;  2B3C A;  1C55 A;  1T1T A;  4CQK A;  1JZA A;  1WMT A;  2YBR C;  2KYQ A;  1LQI A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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