1JZBA

Crystal structure of variant 2 scorpion toxin from centruroides sculpturatus ewing
Total Genus 12
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
12
sequence length
66
structure length
66
Chain Sequence
KEGYLVNKSTGCKYGCLKLGENEGCDKECKAKNQGGSYGYCYAFACWCEGLPESTPTYPLPNKSCS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of variant 2 scorpion toxin from Centruroides sculpturatus Ewing.
pubmed doi rcsb
molecule tags Toxin
molecule keywords NEUROTOXIN 2
total genus 12
structure length 66
sequence length 66
ec nomenclature
pdb deposition date 2001-09-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00537 Toxin_3 Scorpion toxin-like domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.30.10 Alpha Beta 2-Layer Sandwich Defensin A-like Knottin, scorpion toxin-like 1jzbA00
2YEOA 1BRZA 1SEGA 1T7BA 1CHZA 1I6FA 2YBRC 1FH3A 2MZ0A 2M8BB 1JXCA 1DQ7A 2E3FA 1ZYVA 1SN1A 1PE4A 1TI5A 2B68A 2A7TA 1VNBA 1T7EA 2YC1C 2LKBA 1P0AA 2KBHA 1JKZA 1NPIA 5CY0A 1N4NA 2N66A 1ZYWA 1C55A 2I61A 1LQIA 1NH5A 1NE5A 2KYQA 4KYPA 2NY9X 1C56A 1OMYA 1KV0A 2B3CA 1GPSA 2LJ7A 1B3CA 1CN2A 2E0HA 1T0ZA 1BK8A 1P00A 2ASCA 1VNAA 2BRZA 2LY6A 1I6GA 1ICAA 2N2QA 2N69A 2KGQA 2KBKA 1AYJA 1I2UA 1BMRA 2SN3A 2N2RA 2ATBA 1DJTA 1MYNA 2KBJA 4CQKA 4UJ0A 3E7RL 1LQHA 1T1TA 4HE7A 4AAZA 1L4VA 1WT7A 1GPTA 1JZAA 1SNBA 3E7UX 1NRAA 1ZFUA 2KJAA 1WWNA 5KK4A 1LQQA 2LJMA 2LI7A 2GL1A 1ZU3A 3PSMA 1MR4A 2NY8X 1NRBA 1ZVEA 4V1DC 2LT8A 2KSKA 1T7AA 1OZZA 1AHOA 1I2VA 1SN4A 2E3GA 1PTXA 2KPYA 1B7DA 1JZBA 4HHFA 4AEIA 1BCGA 2LY5A 1ZVGA 1WMTA 4AB0A 2LR3A 1ZUTA 1PX9A
chains in the Genus database with same CATH superfamily
3L56A 5AQNA 2YEOA 1BRZA 3QFPA 1SEGA 4UAEF 1T7BA 1K8BA 1CHZA 5BPNA 1I6FA 2YBRC 1UGLA 5AQMA 2MZ0A 1FH3A 3KHWA 2E2FA 2M8BB 1JXCA 1DQ7A 3LDLA 2E3FA 1ZYVA 1SN1A 1PE4A 5AQOA 3A8YA 1POIA 1TI5A 2B68A 3QFUA 5AQXA 2A7TA 1VNBA 1T7EA 2YC1C 3D2EB 2MBKA 2LKBA 3L6QA 1NGIA 3FZKA 5AQLA 5EX5A 1P0AA 2D56A 2KBHA 1NPIA 3D2FB 3QI7A 1N4NA 2N66A 1ZYWA 5CY0A 2QWRA 5F1XA 2I61A 1C55A 5BN9A 1LQIA 1NH5A 2E88A 3R2VA 2YIOA 1HPMA 1NE5A 2KYQA 4KYPA 2NY9X 2YIPA 1C56A 1OMYA 3D2FA 1KV0A 4FL9A 4FSVA 5AQPA 2B3CA 5AQQA 2LN8A 5AQVA 1GPSA 2LJ7A 1B3CA 1CN2A 2QWQA 2E0HA 1T0ZA 3CW4A 1BK8A 1P00A 2ASCA 3KOZA 1VNAA 1NGJA 3C7NB 3LDOA 5FPEA 2BRZA 5AQIA 2JDQD 4HWIA 4GNIA 2LY6A 1I6GA 1ICAA 2N2QA 2BUPA 2QWMA 2N69A 2KGQA 1NGAA 1NGBA 2E8AA 2KBKA 1AYJA 1I2UA 3C7NA 5FPNA 1BMRA 5AR0A 2SN3A 3GDQA 2N2RA 3FZFA 3GKUA 2QXLA 5BN8A 2V7ZA 3JXUA 1JKZA 3FE1A 2ATBA 1BA0A 1DJTA 1MYNA 2KBJA 1HJOA 2K35A 5AQGA 5AQUA 1KAXA 2KHOA 1NGHA 3KOYA 3SF4D 4CQKA 3GL1A 3D2EA 4UJ0A 1QQNA 3E7RL 5BPLA 3M3ZA 1NGDA 1LQHA 1T1TA 3FZMA 1NGCA 4HE7A 3KOWA 4AAZA 1L4VA 1WT7A 1QQOA 3LDPA 1GPTA 3L4IA 1QQMA 1JZAA 2GMOA 1SNBA 3E7UX 5FPDA 3KP0A 2YILA 1NRAA 3BK3C 2QW9A 1ZFUA 4IO8A 2KJAA 3KOXA 2VY6A 1WWNA 1NGFA 3KP1A 5KK4A 1LQQA 2LJMA 5FPMA 3IUCA 3LDNA 4UAFE 1KAYA 2G2KA 2LI7A 4KBOA 5AQRA 2GL1A 1ZU3A 3KC6A 3PSMA 5AQJA 3CQXA 4H5RA 3QMLA 5AQYA 1BUPA 1MR4A 3HSCA 1S3XA 3AY9A 1YUWA 2NY8X 1NRBA 5EVZA 5F0XA 1ZVEA 1NGGA 5AQKA 5EXWA 3ATVA 4V1DC 2LT8A 1BA1A 5AQFA 2KSKA 1T7AA 1OZZA 1AHOA 2QWNA 4UADE 1I2VA 1XRSB 5AQTA 1SN4A 3FZLA 1ATRA 2E3GA 2QWOA 1PTXA 2KPYA 1B7DA 1JZBA 4HHFA 5AQWA 5AQSA 3KVGA 4AEIA 5BPMA 1BCGA 2LY5A 5AQHA 4H5VA 1ATSA 3LDQA 5F2RA 3FZHA 1ZVGA 2QWLA 5AQZA 1KAZA 1WMTA 1NGEA 4AB0A 1HX1A 3I33A 2LR3A 1ZUTA 2QWPA 4H5WA 4H5NA 1DKGD 3ATUA 1PX9A 4H5TA 5EY4A 2MN5A
chains in the Genus database with same CATH topology
2YEOA 1BRZA 1SEGA 1T7BA 1CHZA 1I6FA 2YBRC 1FH3A 2MZ0A 2M8BB 1JXCA 1DQ7A 2E3FA 1ZYVA 1SN1A 1PE4A 1TI5A 2B68A 2A7TA 1VNBA 1T7EA 2YC1C 2LKBA 1P0AA 2KBHA 1JKZA 1NPIA 5CY0A 1N4NA 2N66A 1ZYWA 1C55A 2I61A 1LQIA 1NH5A 1NE5A 2KYQA 4KYPA 2NY9X 1C56A 1OMYA 1KV0A 2B3CA 1GPSA 2LJ7A 1B3CA 1CN2A 2E0HA 1T0ZA 1BK8A 1P00A 2ASCA 1VNAA 2BRZA 2LY6A 1I6GA 1ICAA 2N2QA 2N69A 2KGQA 2KBKA 1AYJA 1I2UA 1BMRA 2SN3A 2N2RA 2ATBA 1DJTA 1MYNA 2KBJA 4CQKA 4UJ0A 3E7RL 1LQHA 1T1TA 4HE7A 4AAZA 1L4VA 1WT7A 1GPTA 1JZAA 1SNBA 3E7UX 1NRAA 1ZFUA 2KJAA 1WWNA 5KK4A 1LQQA 2LJMA 2LI7A 2GL1A 1ZU3A 3PSMA 1MR4A 2NY8X 1NRBA 1ZVEA 4V1DC 2LT8A 2KSKA 1T7AA 1OZZA 1AHOA 1I2VA 1SN4A 2E3GA 1PTXA 2KPYA 1B7DA 1JZBA 4HHFA 4AEIA 1BCGA 2LY5A 1ZVGA 1WMTA 4AB0A 2LR3A 1ZUTA 1PX9A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2YEO A;  1BRZ A;  1SEG A;  1T7B A;  1CHZ A;  1I6F A;  2YBR C;  1FH3 A;  2MZ0 A;  2M8B B;  1JXC A;  1DQ7 A;  2E3F A;  1ZYV A;  1SN1 A;  1PE4 A;  1TI5 A;  2B68 A;  2A7T A;  1VNB A;  1T7E A;  2YC1 C;  2LKB A;  1P0A A;  2KBH A;  1JKZ A;  1NPI A;  5CY0 A;  1N4N A;  2N66 A;  1ZYW A;  1C55 A;  2I61 A;  1LQI A;  1NH5 A;  1NE5 A;  2KYQ A;  4KYP A;  2NY9 X;  1C56 A;  1OMY A;  1KV0 A;  2B3C A;  1GPS A;  2LJ7 A;  1B3C A;  1CN2 A;  2E0H A;  1T0Z A;  1BK8 A;  1P00 A;  2ASC A;  1VNA A;  2BRZ A;  2LY6 A;  1I6G A;  1ICA A;  2N2Q A;  2N69 A;  2KGQ A;  2KBK A;  1AYJ A;  1I2U A;  1BMR A;  2SN3 A;  2N2R A;  2ATB A;  1DJT A;  1MYN A;  2KBJ A;  4CQK A;  4UJ0 A;  3E7R L;  1LQH A;  1T1T A;  4HE7 A;  4AAZ A;  1L4V A;  1WT7 A;  1GPT A;  1JZA A;  1SNB A;  3E7U X;  1NRA A;  1ZFU A;  2KJA A;  1WWN A;  5KK4 A;  1LQQ A;  2LJM A;  2LI7 A;  2GL1 A;  1ZU3 A;  3PSM A;  1MR4 A;  2NY8 X;  1NRB A;  1ZVE A;  4V1D C;  2LT8 A;  2KSK A;  1T7A A;  1OZZ A;  1AHO A;  1I2V A;  1SN4 A;  2E3G A;  1PTX A;  2KPY A;  1B7D A;  1JZB A;  4HHF A;  4AEI A;  1BCG A;  2LY5 A;  1ZVG A;  1WMT A;  4AB0 A;  2LR3 A;  1ZUT A;  1PX9 A; 
#chains in the Genus database with same CATH topology
 3L56 A;  5AQN A;  2YEO A;  1BRZ A;  3QFP A;  1SEG A;  4UAE F;  1T7B A;  1K8B A;  1CHZ A;  5BPN A;  1I6F A;  2YBR C;  1UGL A;  5AQM A;  2MZ0 A;  1FH3 A;  3KHW A;  2E2F A;  2M8B B;  1JXC A;  1DQ7 A;  3LDL A;  2E3F A;  1ZYV A;  1SN1 A;  1PE4 A;  5AQO A;  3A8Y A;  1POI A;  1TI5 A;  2B68 A;  3QFU A;  5AQX A;  2A7T A;  1VNB A;  1T7E A;  2YC1 C;  3D2E B;  2MBK A;  2LKB A;  3L6Q A;  1NGI A;  3FZK A;  5AQL A;  5EX5 A;  1P0A A;  2D56 A;  2KBH A;  1NPI A;  3D2F B;  3QI7 A;  1N4N A;  2N66 A;  1ZYW A;  5CY0 A;  2QWR A;  5F1X A;  2I61 A;  1C55 A;  5BN9 A;  1LQI A;  1NH5 A;  2E88 A;  3R2V A;  2YIO A;  1HPM A;  1NE5 A;  2KYQ A;  4KYP A;  2NY9 X;  2YIP A;  1C56 A;  1OMY A;  3D2F A;  1KV0 A;  4FL9 A;  4FSV A;  5AQP A;  2B3C A;  5AQQ A;  2LN8 A;  5AQV A;  1GPS A;  2LJ7 A;  1B3C A;  1CN2 A;  2QWQ A;  2E0H A;  1T0Z A;  3CW4 A;  1BK8 A;  1P00 A;  2ASC A;  3KOZ A;  1VNA A;  1NGJ A;  3C7N B;  3LDO A;  5FPE A;  2BRZ A;  5AQI A;  2JDQ D;  4HWI A;  4GNI A;  2LY6 A;  1I6G A;  1ICA A;  2N2Q A;  2BUP A;  2QWM A;  2N69 A;  2KGQ A;  1NGA A;  1NGB A;  2E8A A;  2KBK A;  1AYJ A;  1I2U A;  3C7N A;  5FPN A;  1BMR A;  5AR0 A;  2SN3 A;  3GDQ A;  2N2R A;  3FZF A;  3GKU A;  2QXL A;  5BN8 A;  2V7Z A;  3JXU A;  1JKZ A;  3FE1 A;  2ATB A;  1BA0 A;  1DJT A;  1MYN A;  2KBJ A;  1HJO A;  2K35 A;  5AQG A;  5AQU A;  1KAX A;  2KHO A;  1NGH A;  3KOY A;  3SF4 D;  4CQK A;  3GL1 A;  3D2E A;  4UJ0 A;  1QQN A;  3E7R L;  5BPL A;  3M3Z A;  1NGD A;  1LQH A;  1T1T A;  3FZM A;  1NGC A;  4HE7 A;  3KOW A;  4AAZ A;  1L4V A;  1WT7 A;  1QQO A;  3LDP A;  1GPT A;  3L4I A;  1QQM A;  1JZA A;  2GMO A;  1SNB A;  3E7U X;  5FPD A;  3KP0 A;  2YIL A;  1NRA A;  3BK3 C;  2QW9 A;  1ZFU A;  4IO8 A;  2KJA A;  3KOX A;  2VY6 A;  1WWN A;  1NGF A;  3KP1 A;  5KK4 A;  1LQQ A;  2LJM A;  5FPM A;  3IUC A;  3LDN A;  4UAF E;  1KAY A;  2G2K A;  2LI7 A;  4KBO A;  5AQR A;  2GL1 A;  1ZU3 A;  3KC6 A;  3PSM A;  5AQJ A;  3CQX A;  4H5R A;  3QML A;  5AQY A;  1BUP A;  1MR4 A;  3HSC A;  1S3X A;  3AY9 A;  1YUW A;  2NY8 X;  1NRB A;  5EVZ A;  5F0X A;  1ZVE A;  1NGG A;  5AQK A;  5EXW A;  3ATV A;  4V1D C;  2LT8 A;  1BA1 A;  5AQF A;  2KSK A;  1T7A A;  1OZZ A;  1AHO A;  2QWN A;  4UAD E;  1I2V A;  1XRS B;  5AQT A;  1SN4 A;  3FZL A;  1ATR A;  2E3G A;  2QWO A;  1PTX A;  2KPY A;  1B7D A;  1JZB A;  4HHF A;  5AQW A;  5AQS A;  3KVG A;  4AEI A;  5BPM A;  1BCG A;  2LY5 A;  5AQH A;  4H5V A;  1ATS A;  3LDQ A;  5F2R A;  3FZH A;  1ZVG A;  2QWL A;  5AQZ A;  1KAZ A;  1WMT A;  1NGE A;  4AB0 A;  1HX1 A;  3I33 A;  2LR3 A;  1ZUT A;  2QWP A;  4H5W A;  4H5N A;  1DKG D;  3ATU A;  1PX9 A;  4H5T A;  5EY4 A;  2MN5 A; 
#chains in the Genus database with same CATH homology
 2YEO A;  1BRZ A;  1SEG A;  1T7B A;  1CHZ A;  1I6F A;  2YBR C;  1FH3 A;  2MZ0 A;  2M8B B;  1JXC A;  1DQ7 A;  2E3F A;  1ZYV A;  1SN1 A;  1PE4 A;  1TI5 A;  2B68 A;  2A7T A;  1VNB A;  1T7E A;  2YC1 C;  2LKB A;  1P0A A;  2KBH A;  1JKZ A;  1NPI A;  5CY0 A;  1N4N A;  2N66 A;  1ZYW A;  1C55 A;  2I61 A;  1LQI A;  1NH5 A;  1NE5 A;  2KYQ A;  4KYP A;  2NY9 X;  1C56 A;  1OMY A;  1KV0 A;  2B3C A;  1GPS A;  2LJ7 A;  1B3C A;  1CN2 A;  2E0H A;  1T0Z A;  1BK8 A;  1P00 A;  2ASC A;  1VNA A;  2BRZ A;  2LY6 A;  1I6G A;  1ICA A;  2N2Q A;  2N69 A;  2KGQ A;  2KBK A;  1AYJ A;  1I2U A;  1BMR A;  2SN3 A;  2N2R A;  2ATB A;  1DJT A;  1MYN A;  2KBJ A;  4CQK A;  4UJ0 A;  3E7R L;  1LQH A;  1T1T A;  4HE7 A;  4AAZ A;  1L4V A;  1WT7 A;  1GPT A;  1JZA A;  1SNB A;  3E7U X;  1NRA A;  1ZFU A;  2KJA A;  1WWN A;  5KK4 A;  1LQQ A;  2LJM A;  2LI7 A;  2GL1 A;  1ZU3 A;  3PSM A;  1MR4 A;  2NY8 X;  1NRB A;  1ZVE A;  4V1D C;  2LT8 A;  2KSK A;  1T7A A;  1OZZ A;  1AHO A;  1I2V A;  1SN4 A;  2E3G A;  1PTX A;  2KPY A;  1B7D A;  1JZB A;  4HHF A;  4AEI A;  1BCG A;  2LY5 A;  1ZVG A;  1WMT A;  4AB0 A;  2LR3 A;  1ZUT A;  1PX9 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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