1NPIA

Tityus serrulatus neurotoxin (ts1) at atomic resolution
Total Genus 10
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
10
sequence length
61
structure length
61
Chain Sequence
KEGYLMDHEGCKLSCFIRPSGYCGRECGIKKGSSGYCAWPACYCYGLPNWVKVWDRATNKC
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Toxin
publication title Structural analysis of Tityus serrulatus Ts1 neurotoxin at atomic resolution: insights into interactions with Na+ channels.
pubmed doi rcsb
molecule keywords Toxin VII
total genus 10
structure length 61
sequence length 61
ec nomenclature
pdb deposition date 2003-01-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00537 Toxin_3 Scorpion toxin-like domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.30.10 Alpha Beta 2-Layer Sandwich Defensin A-like Knottin, scorpion toxin-like 1npiA00
3E7UX 2E0HA 2B3CA 1T7AA 1VNBA 1B7DA 2KSKA 2N66A 4V1DC 1L4VA 2E3FA 1TI5A 1DJTA 1N4NA 1SNBA 1C56A 1CHZA 1SN1A 2I61A 2KBJA 2LJ7A 1MYNA 2N2QA 4AEIA 2LR3A 4HHFA 1T7EA 2ASCA 1NPIA 2KBHA 1PE4A 1P0AA 2N69A 2E3GA 1LQIA 2NY8X 2GL1A 2N2RA 1BMRA 1BCGA 4HE7A 3PSMA 1I6FA 2KPYA 2KJAA 1NRBA 1I6GA 1ZYVA 4CQKA 1SEGA 1T0ZA 1OMYA 2MZ0A 4AB0A 1LQHA 1JXCA 4UJ0A 1BRZA 1OZZA 2KGQA 2LKBA 1CN2A 2LI7A 1WT7A 1B3CA 1AHOA 5CY0A 1GPTA 1PX9A 1I2VA 1WMTA 1ZUTA 1WWNA 2YBRC 5KK4A 2NY9X 2KBKA 1NE5A 1FH3A 1JZAA 1MR4A 2KYQA 1ZFUA 1NH5A 2YEOA 1LQQA 2BRZA 1T7BA 2LT8A 2LY5A 2ATBA 1NRAA 1JKZA 2A7TA 2M8BB 1JZBA 4AAZA 1I2UA 2B68A 1ICAA 1GPSA 1DQ7A 1T1TA 1SN4A 1ZU3A 1C55A 1ZYWA 1ZVGA 1ZVEA 2SN3A 3E7RL 2LJMA 2YC1C 2LY6A 1KV0A 1AYJA 1PTXA 1BK8A 1VNAA 1P00A 4KYPA
chains in the Genus database with same CATH superfamily
5F2RA 3KVGA 1ATRA 3E7UX 5EVZA 2QWLA 1NGBA 2E0HA 2B3CA 1T7AA 4KBOA 3HSCA 3QMLA 1VNBA 1B7DA 2KSKA 5AQLA 3D2FA 1HJOA 5AQWA 2LN8A 2D56A 2N66A 5AQIA 3ATVA 3A8YA 3QI7A 4V1DC 1L4VA 1POIA 2E3FA 1TI5A 3JXUA 1DJTA 2MN5A 1N4NA 1NGJA 1SNBA 1C56A 5FPMA 1CHZA 1SN1A 2I61A 2KBJA 1KAZA 3LDLA 2LJ7A 1MYNA 5AQVA 2N2QA 4AEIA 3L4IA 4H5NA 5EY4A 1BA1A 2LR3A 3C7NA 4HHFA 5AQOA 1T7EA 1NPIA 2ASCA 3BK3C 3KOWA 2KBHA 1DKGD 1PE4A 1P0AA 2N69A 2E3GA 4H5WA 1LQIA 2NY8X 3KP0A 3I33A 2GL1A 2N2RA 5AQRA 1BMRA 1HX1A 5BPMA 1BCGA 2E2FA 4HE7A 1KAYA 3PSMA 1I6FA 2JDQD 2KPYA 5BN8A 3SF4D 2KJAA 3LDQA 1NRBA 3LDOA 1I6GA 1C55A 1QQMA 3FZMA 2MBKA 1ZYVA 4CQKA 1SEGA 1QQNA 1KAXA 1NGHA 1T0ZA 4FL9A 5AQPA 1OMYA 2MZ0A 3CQXA 2QW9A 4AB0A 3L56A 4UAFE 5FPNA 1LQHA 1JXCA 3FZFA 5AQXA 1OZZA 2KGQA 2LKBA 4H5TA 2LI7A 5AQSA 4UJ0A 5FPDA 1HPMA 1WT7A 3D2EB 5BPLA 1B3CA 5AQTA 3GL1A 5AQUA 1AHOA 5CY0A 5FPEA 2QWOA 4UADE 1PX9A 3QFPA 1GPTA 1I2VA 3FZKA 1WMTA 1NGCA 1WWNA 1ZUTA 2YBRC 1NGDA 2YIPA 5AQJA 5KK4A 2QWRA 1QQOA 2NY9X 2QWQA 2VY6A 3KOXA 5AQKA 4H5VA 2K35A 3KP1A 5EXWA 2KBKA 3ATUA 1NE5A 3QFUA 3GKUA 3KOZA 1FH3A 3D2FB 3LDNA 5AQGA 1K8BA 1JZAA 1MR4A 1NGGA 2KYQA 1ZFUA 2QWMA 1CN2A 1NH5A 2YEOA 1LQQA 3KC6A 4UAEF 4HWIA 2BRZA 1T7BA 2E8AA 3M3ZA 5AQYA 2LT8A 2QWNA 2LY5A 2YIOA 2ATBA 1NRAA 2E88A 1BRZA 1JKZA 2A7TA 2M8BB 3FZHA 1JZBA 3LDPA 3R2VA 1NGIA 3KOYA 4AAZA 2GMOA 1I2UA 2BUPA 5AR0A 3FZLA 2B68A 5AQHA 5AQZA 4FSVA 1ICAA 3C7NB 3AY9A 5AQFA 1GPSA 1BUPA 5EX5A 1NGAA 5AQNA 5AQQA 1DQ7A 2YILA 1T1TA 1ATSA 1SN4A 1UGLA 2G2KA 1ZU3A 2KHOA 3GDQA 3IUCA 2V7ZA 1S3XA 5F1XA 3D2EA 1ZYWA 1NGEA 1ZVGA 3FE1A 4IO8A 1ZVEA 2SN3A 3E7RL 2LJMA 2YC1C 2LY6A 4GNIA 5BPNA 4H5RA 1KV0A 3KHWA 3CW4A 5F0XA 1AYJA 1XRSB 1NGFA 2QXLA 1PTXA 1BK8A 1VNAA 2QWPA 1BA0A 3L6QA 5AQMA 5BN9A 1P00A 4KYPA 1YUWA
chains in the Genus database with same CATH topology
3E7UX 2E0HA 2B3CA 1T7AA 1VNBA 1B7DA 2KSKA 2N66A 4V1DC 1L4VA 2E3FA 1TI5A 1DJTA 1N4NA 1SNBA 1C56A 1CHZA 1SN1A 2I61A 2KBJA 2LJ7A 1MYNA 2N2QA 4AEIA 2LR3A 4HHFA 1T7EA 2ASCA 1NPIA 2KBHA 1PE4A 1P0AA 2N69A 2E3GA 1LQIA 2NY8X 2GL1A 2N2RA 1BMRA 1BCGA 4HE7A 3PSMA 1I6FA 2KPYA 2KJAA 1NRBA 1I6GA 1ZYVA 4CQKA 1SEGA 1T0ZA 1OMYA 2MZ0A 4AB0A 1LQHA 1JXCA 4UJ0A 1BRZA 1OZZA 2KGQA 2LKBA 1CN2A 2LI7A 1WT7A 1B3CA 1AHOA 5CY0A 1GPTA 1PX9A 1I2VA 1WMTA 1ZUTA 1WWNA 2YBRC 5KK4A 2NY9X 2KBKA 1NE5A 1FH3A 1JZAA 1MR4A 2KYQA 1ZFUA 1NH5A 2YEOA 1LQQA 2BRZA 1T7BA 2LT8A 2LY5A 2ATBA 1NRAA 1JKZA 2A7TA 2M8BB 1JZBA 4AAZA 1I2UA 2B68A 1ICAA 1GPSA 1DQ7A 1T1TA 1SN4A 1ZU3A 1C55A 1ZYWA 1ZVGA 1ZVEA 2SN3A 3E7RL 2LJMA 2YC1C 2LY6A 1KV0A 1AYJA 1PTXA 1BK8A 1VNAA 1P00A 4KYPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3E7U X;  2E0H A;  2B3C A;  1T7A A;  1VNB A;  1B7D A;  2KSK A;  2N66 A;  4V1D C;  1L4V A;  2E3F A;  1TI5 A;  1DJT A;  1N4N A;  1SNB A;  1C56 A;  1CHZ A;  1SN1 A;  2I61 A;  2KBJ A;  2LJ7 A;  1MYN A;  2N2Q A;  4AEI A;  2LR3 A;  4HHF A;  1T7E A;  2ASC A;  1NPI A;  2KBH A;  1PE4 A;  1P0A A;  2N69 A;  2E3G A;  1LQI A;  2NY8 X;  2GL1 A;  2N2R A;  1BMR A;  1BCG A;  4HE7 A;  3PSM A;  1I6F A;  2KPY A;  2KJA A;  1NRB A;  1I6G A;  1ZYV A;  4CQK A;  1SEG A;  1T0Z A;  1OMY A;  2MZ0 A;  4AB0 A;  1LQH A;  1JXC A;  4UJ0 A;  1BRZ A;  1OZZ A;  2KGQ A;  2LKB A;  1CN2 A;  2LI7 A;  1WT7 A;  1B3C A;  1AHO A;  5CY0 A;  1GPT A;  1PX9 A;  1I2V A;  1WMT A;  1ZUT A;  1WWN A;  2YBR C;  5KK4 A;  2NY9 X;  2KBK A;  1NE5 A;  1FH3 A;  1JZA A;  1MR4 A;  2KYQ A;  1ZFU A;  1NH5 A;  2YEO A;  1LQQ A;  2BRZ A;  1T7B A;  2LT8 A;  2LY5 A;  2ATB A;  1NRA A;  1JKZ A;  2A7T A;  2M8B B;  1JZB A;  4AAZ A;  1I2U A;  2B68 A;  1ICA A;  1GPS A;  1DQ7 A;  1T1T A;  1SN4 A;  1ZU3 A;  1C55 A;  1ZYW A;  1ZVG A;  1ZVE A;  2SN3 A;  3E7R L;  2LJM A;  2YC1 C;  2LY6 A;  1KV0 A;  1AYJ A;  1PTX A;  1BK8 A;  1VNA A;  1P00 A;  4KYP A; 
#chains in the Genus database with same CATH topology
 5F2R A;  3KVG A;  1ATR A;  3E7U X;  5EVZ A;  2QWL A;  1NGB A;  2E0H A;  2B3C A;  1T7A A;  4KBO A;  3HSC A;  3QML A;  1VNB A;  1B7D A;  2KSK A;  5AQL A;  3D2F A;  1HJO A;  5AQW A;  2LN8 A;  2D56 A;  2N66 A;  5AQI A;  3ATV A;  3A8Y A;  3QI7 A;  4V1D C;  1L4V A;  1POI A;  2E3F A;  1TI5 A;  3JXU A;  1DJT A;  2MN5 A;  1N4N A;  1NGJ A;  1SNB A;  1C56 A;  5FPM A;  1CHZ A;  1SN1 A;  2I61 A;  2KBJ A;  1KAZ A;  3LDL A;  2LJ7 A;  1MYN A;  5AQV A;  2N2Q A;  4AEI A;  3L4I A;  4H5N A;  5EY4 A;  1BA1 A;  2LR3 A;  3C7N A;  4HHF A;  5AQO A;  1T7E A;  1NPI A;  2ASC A;  3BK3 C;  3KOW A;  2KBH A;  1DKG D;  1PE4 A;  1P0A A;  2N69 A;  2E3G A;  4H5W A;  1LQI A;  2NY8 X;  3KP0 A;  3I33 A;  2GL1 A;  2N2R A;  5AQR A;  1BMR A;  1HX1 A;  5BPM A;  1BCG A;  2E2F A;  4HE7 A;  1KAY A;  3PSM A;  1I6F A;  2JDQ D;  2KPY A;  5BN8 A;  3SF4 D;  2KJA A;  3LDQ A;  1NRB A;  3LDO A;  1I6G A;  1C55 A;  1QQM A;  3FZM A;  2MBK A;  1ZYV A;  4CQK A;  1SEG A;  1QQN A;  1KAX A;  1NGH A;  1T0Z A;  4FL9 A;  5AQP A;  1OMY A;  2MZ0 A;  3CQX A;  2QW9 A;  4AB0 A;  3L56 A;  4UAF E;  5FPN A;  1LQH A;  1JXC A;  3FZF A;  5AQX A;  1OZZ A;  2KGQ A;  2LKB A;  4H5T A;  2LI7 A;  5AQS A;  4UJ0 A;  5FPD A;  1HPM A;  1WT7 A;  3D2E B;  5BPL A;  1B3C A;  5AQT A;  3GL1 A;  5AQU A;  1AHO A;  5CY0 A;  5FPE A;  2QWO A;  4UAD E;  1PX9 A;  3QFP A;  1GPT A;  1I2V A;  3FZK A;  1WMT A;  1NGC A;  1WWN A;  1ZUT A;  2YBR C;  1NGD A;  2YIP A;  5AQJ A;  5KK4 A;  2QWR A;  1QQO A;  2NY9 X;  2QWQ A;  2VY6 A;  3KOX A;  5AQK A;  4H5V A;  2K35 A;  3KP1 A;  5EXW A;  2KBK A;  3ATU A;  1NE5 A;  3QFU A;  3GKU A;  3KOZ A;  1FH3 A;  3D2F B;  3LDN A;  5AQG A;  1K8B A;  1JZA A;  1MR4 A;  1NGG A;  2KYQ A;  1ZFU A;  2QWM A;  1CN2 A;  1NH5 A;  2YEO A;  1LQQ A;  3KC6 A;  4UAE F;  4HWI A;  2BRZ A;  1T7B A;  2E8A A;  3M3Z A;  5AQY A;  2LT8 A;  2QWN A;  2LY5 A;  2YIO A;  2ATB A;  1NRA A;  2E88 A;  1BRZ A;  1JKZ A;  2A7T A;  2M8B B;  3FZH A;  1JZB A;  3LDP A;  3R2V A;  1NGI A;  3KOY A;  4AAZ A;  2GMO A;  1I2U A;  2BUP A;  5AR0 A;  3FZL A;  2B68 A;  5AQH A;  5AQZ A;  4FSV A;  1ICA A;  3C7N B;  3AY9 A;  5AQF A;  1GPS A;  1BUP A;  5EX5 A;  1NGA A;  5AQN A;  5AQQ A;  1DQ7 A;  2YIL A;  1T1T A;  1ATS A;  1SN4 A;  1UGL A;  2G2K A;  1ZU3 A;  2KHO A;  3GDQ A;  3IUC A;  2V7Z A;  1S3X A;  5F1X A;  3D2E A;  1ZYW A;  1NGE A;  1ZVG A;  3FE1 A;  4IO8 A;  1ZVE A;  2SN3 A;  3E7R L;  2LJM A;  2YC1 C;  2LY6 A;  4GNI A;  5BPN A;  4H5R A;  1KV0 A;  3KHW A;  3CW4 A;  5F0X A;  1AYJ A;  1XRS B;  1NGF A;  2QXL A;  1PTX A;  1BK8 A;  1VNA A;  2QWP A;  1BA0 A;  3L6Q A;  5AQM A;  5BN9 A;  1P00 A;  4KYP A;  1YUW A; 
#chains in the Genus database with same CATH homology
 3E7U X;  2E0H A;  2B3C A;  1T7A A;  1VNB A;  1B7D A;  2KSK A;  2N66 A;  4V1D C;  1L4V A;  2E3F A;  1TI5 A;  1DJT A;  1N4N A;  1SNB A;  1C56 A;  1CHZ A;  1SN1 A;  2I61 A;  2KBJ A;  2LJ7 A;  1MYN A;  2N2Q A;  4AEI A;  2LR3 A;  4HHF A;  1T7E A;  2ASC A;  1NPI A;  2KBH A;  1PE4 A;  1P0A A;  2N69 A;  2E3G A;  1LQI A;  2NY8 X;  2GL1 A;  2N2R A;  1BMR A;  1BCG A;  4HE7 A;  3PSM A;  1I6F A;  2KPY A;  2KJA A;  1NRB A;  1I6G A;  1ZYV A;  4CQK A;  1SEG A;  1T0Z A;  1OMY A;  2MZ0 A;  4AB0 A;  1LQH A;  1JXC A;  4UJ0 A;  1BRZ A;  1OZZ A;  2KGQ A;  2LKB A;  1CN2 A;  2LI7 A;  1WT7 A;  1B3C A;  1AHO A;  5CY0 A;  1GPT A;  1PX9 A;  1I2V A;  1WMT A;  1ZUT A;  1WWN A;  2YBR C;  5KK4 A;  2NY9 X;  2KBK A;  1NE5 A;  1FH3 A;  1JZA A;  1MR4 A;  2KYQ A;  1ZFU A;  1NH5 A;  2YEO A;  1LQQ A;  2BRZ A;  1T7B A;  2LT8 A;  2LY5 A;  2ATB A;  1NRA A;  1JKZ A;  2A7T A;  2M8B B;  1JZB A;  4AAZ A;  1I2U A;  2B68 A;  1ICA A;  1GPS A;  1DQ7 A;  1T1T A;  1SN4 A;  1ZU3 A;  1C55 A;  1ZYW A;  1ZVG A;  1ZVE A;  2SN3 A;  3E7R L;  2LJM A;  2YC1 C;  2LY6 A;  1KV0 A;  1AYJ A;  1PTX A;  1BK8 A;  1VNA A;  1P00 A;  4KYP A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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