1NRAA

Solution structure of an old world-like neurotoxin from the venom of the new world scorpion centruroides sculpturatus ewing
Total Genus 13
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
13
sequence length
63
structure length
63
Chain Sequence
KKDGYPVDSGNCKYECLKDDYCNDLCLERKADKGYCYWGKVSCYCYGLPDNSPTKTSGKCNPA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Solution structure of an Old World-like neurotoxin from the venom of the New World scorpion Centruroides sculpturatus Ewing.
pubmed rcsb
molecule tags Neurotoxin
source organism Centruroides sculpturatus
molecule keywords NEUROTOXIN V, CSE-V
total genus 13
structure length 63
sequence length 63
ec nomenclature
pdb deposition date 1995-01-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00537 Toxin_3 Scorpion toxin-like domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.30.10 Alpha Beta 2-Layer Sandwich Defensin A-like Knottin, scorpion toxin-like 1nraA00
1JXCA 2N69A 1L4VA 2LJMA 1MYNA 1WWNA 1JKZA 1KV0A 1TI5A 2ASCA 1SN4A 1OMYA 2KBJA 1VNAA 2KSKA 1B7DA 1GPSA 2BRZA 1WT7A 2NY9X 4V1DC 1ZVGA 1ZVEA 1ZYVA 1JZAA 2GL1A 1GPTA 4UJ0A 2YBRC 2E3FA 1PE4A 2LT8A 1BCGA 1T7EA 1ZUTA 1LQIA 2M8BB 2KBKA 3E7RL 1I2UA 2LR3A 1ZYWA 1SNBA 2YC1C 2N66A 1FH3A 4AEIA 1B3CA 1JZBA 2LI7A 1ICAA 1AHOA 2ATBA 4AB0A 3PSMA 1BMRA 1OZZA 2I61A 1P00A 2B68A 2E0HA 2LY6A 1MR4A 2KBHA 2NY8X 1NRAA 1ZFUA 2A7TA 1N4NA 1C55A 1AYJA 3E7UX 1NE5A 1T7BA 2N2QA 1NRBA 2KJAA 2SN3A 1C56A 4HHFA 2KPYA 5KK4A 1NPIA 4HE7A 1SN1A 1BRZA 1LQQA 1DJTA 1PX9A 2KYQA 1BK8A 1T7AA 1SEGA 1PTXA 2KGQA 2LKBA 2N2RA 4CQKA 1I2VA 4KYPA 1T0ZA 1ZU3A 1NH5A 2B3CA 1P0AA 1CHZA 1WMTA 1LQHA 2MZ0A 1VNBA 1I6FA 1CN2A 2LY5A 4AAZA 1T1TA 2LJ7A 2E3GA 2YEOA 1I6GA 1DQ7A 5CY0A
chains in the Genus database with same CATH superfamily
1JXCA 2N69A 1L4VA 2LJMA 1NGEA 3KOZA 5AQGA 1MYNA 1WWNA 2YIOA 1KV0A 3LDPA 5FPEA 2QWRA 1JKZA 5AQJA 3QFPA 2QW9A 3JXUA 2V7ZA 4HWIA 4UADE 3C7NA 3SF4D 1BA0A 1BUPA 1ATRA 1HJOA 1TI5A 2ASCA 1SN4A 1OMYA 3GL1A 2KBJA 5AQRA 5AQTA 1VNAA 3D2EA 4FSVA 2KSKA 1I2VA 1XRSB 1B7DA 1QQNA 1QQOA 2QWMA 1GPSA 2BRZA 1WT7A 2NY9X 5AR0A 5AQMA 4V1DC 3L6QA 1ZVGA 1ZVEA 5BPNA 1ZYVA 1JZAA 3KOWA 2E2FA 5FPDA 1BA1A 2QXLA 5BN8A 2BUPA 2GL1A 1GPTA 4UJ0A 2YBRC 2QWNA 1NGCA 2E3FA 5AQWA 1PE4A 5BPLA 3FZKA 3CW4A 2LT8A 5BPMA 1BCGA 1T7EA 1S3XA 1ZUTA 1LQIA 2MBKA 3L56A 2M8BB 4H5TA 1NGBA 2KBKA 3E7RL 2YIPA 1I2UA 5EVZA 2LR3A 1NGJA 1KAYA 1SNBA 1ZYWA 3HSCA 5AQPA 4FL9A 3D2EB 4H5VA 1DKGD 2YC1C 2G2KA 2N66A 2QWOA 3ATVA 5AQKA 3LDLA 3D2FA 4AEIA 1FH3A 1KAZA 2KHOA 1B3CA 3QMLA 3KP0A 1JZBA 2LI7A 4GNIA 1ICAA 1AHOA 2ATBA 3KOXA 4AB0A 3GKUA 3GDQA 3PSMA 5EXWA 1OZZA 5EX5A 4CQKA 1BMRA 5F2RA 3R2VA 2I61A 4IO8A 3KC6A 3KOYA 5F1XA 1NGAA 4UAFE 1P00A 2B68A 2E0HA 2LY6A 1MR4A 2KBHA 2LN8A 1KAXA 3KP1A 5F0XA 2NY8X 1NRAA 1ZFUA 2A7TA 3C7NB 1N4NA 3FZLA 3LDNA 1C55A 1AYJA 3E7UX 5AQZA 1ATSA 1NE5A 2JDQD 5AQIA 1YUWA 2D56A 2VY6A 1T7BA 2N2QA 5AQHA 1NRBA 3D2FB 5AQFA 2KJAA 2SN3A 3L4IA 1UGLA 1C56A 4HHFA 3FZHA 2KPYA 5KK4A 1NPIA 2E8AA 3IUCA 4HE7A 2MN5A 3BK3C 1SN1A 2QWLA 2E88A 3FE1A 1BRZA 3ATUA 5AQYA 4H5NA 5AQLA 3QI7A 1LQQA 1HX1A 1NGHA 5EY4A 3QFUA 1DJTA 1NGDA 3LDQA 2GMOA 3CQXA 1PX9A 2KYQA 1BK8A 1QQMA 1T7AA 1SEGA 1PTXA 2KGQA 5AQUA 5AQSA 5BN9A 2LKBA 4H5WA 3KHWA 5FPNA 3AY9A 2N2RA 3FZFA 5AQVA 4KYPA 2YILA 2QWQA 1T0ZA 4KBOA 5AQOA 4UAEF 5AQXA 1NGFA 5AQNA 1ZU3A 1NH5A 1K8BA 3M3ZA 2B3CA 1P0AA 1HPMA 1CHZA 1WMTA 1NGGA 1LQHA 1POIA 1VNBA 2MZ0A 1I6FA 2QWPA 5AQQA 5FPMA 2LY5A 1CN2A 4AAZA 2K35A 1T1TA 2LJ7A 1NGIA 3I33A 2E3GA 3KVGA 3LDOA 2YEOA 3FZMA 4H5RA 1I6GA 3A8YA 1DQ7A 5CY0A
chains in the Genus database with same CATH topology
1JXCA 2N69A 1L4VA 2LJMA 1MYNA 1WWNA 1JKZA 1KV0A 1TI5A 2ASCA 1SN4A 1OMYA 2KBJA 1VNAA 2KSKA 1B7DA 1GPSA 2BRZA 1WT7A 2NY9X 4V1DC 1ZVGA 1ZVEA 1ZYVA 1JZAA 2GL1A 1GPTA 4UJ0A 2YBRC 2E3FA 1PE4A 2LT8A 1BCGA 1T7EA 1ZUTA 1LQIA 2M8BB 2KBKA 3E7RL 1I2UA 2LR3A 1ZYWA 1SNBA 2YC1C 2N66A 1FH3A 4AEIA 1B3CA 1JZBA 2LI7A 1ICAA 1AHOA 2ATBA 4AB0A 3PSMA 1BMRA 1OZZA 2I61A 1P00A 2B68A 2E0HA 2LY6A 1MR4A 2KBHA 2NY8X 1NRAA 1ZFUA 2A7TA 1N4NA 1C55A 1AYJA 3E7UX 1NE5A 1T7BA 2N2QA 1NRBA 2KJAA 2SN3A 1C56A 4HHFA 2KPYA 5KK4A 1NPIA 4HE7A 1SN1A 1BRZA 1LQQA 1DJTA 1PX9A 2KYQA 1BK8A 1T7AA 1SEGA 1PTXA 2KGQA 2LKBA 2N2RA 4CQKA 1I2VA 4KYPA 1T0ZA 1ZU3A 1NH5A 2B3CA 1P0AA 1CHZA 1WMTA 1LQHA 2MZ0A 1VNBA 1I6FA 1CN2A 2LY5A 4AAZA 1T1TA 2LJ7A 2E3GA 2YEOA 1I6GA 1DQ7A 5CY0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1JXC A;  2N69 A;  1L4V A;  2LJM A;  1MYN A;  1WWN A;  1JKZ A;  1KV0 A;  1TI5 A;  2ASC A;  1SN4 A;  1OMY A;  2KBJ A;  1VNA A;  2KSK A;  1B7D A;  1GPS A;  2BRZ A;  1WT7 A;  2NY9 X;  4V1D C;  1ZVG A;  1ZVE A;  1ZYV A;  1JZA A;  2GL1 A;  1GPT A;  4UJ0 A;  2YBR C;  2E3F A;  1PE4 A;  2LT8 A;  1BCG A;  1T7E A;  1ZUT A;  1LQI A;  2M8B B;  2KBK A;  3E7R L;  1I2U A;  2LR3 A;  1ZYW A;  1SNB A;  2YC1 C;  2N66 A;  1FH3 A;  4AEI A;  1B3C A;  1JZB A;  2LI7 A;  1ICA A;  1AHO A;  2ATB A;  4AB0 A;  3PSM A;  1BMR A;  1OZZ A;  2I61 A;  1P00 A;  2B68 A;  2E0H A;  2LY6 A;  1MR4 A;  2KBH A;  2NY8 X;  1NRA A;  1ZFU A;  2A7T A;  1N4N A;  1C55 A;  1AYJ A;  3E7U X;  1NE5 A;  1T7B A;  2N2Q A;  1NRB A;  2KJA A;  2SN3 A;  1C56 A;  4HHF A;  2KPY A;  5KK4 A;  1NPI A;  4HE7 A;  1SN1 A;  1BRZ A;  1LQQ A;  1DJT A;  1PX9 A;  2KYQ A;  1BK8 A;  1T7A A;  1SEG A;  1PTX A;  2KGQ A;  2LKB A;  2N2R A;  4CQK A;  1I2V A;  4KYP A;  1T0Z A;  1ZU3 A;  1NH5 A;  2B3C A;  1P0A A;  1CHZ A;  1WMT A;  1LQH A;  2MZ0 A;  1VNB A;  1I6F A;  1CN2 A;  2LY5 A;  4AAZ A;  1T1T A;  2LJ7 A;  2E3G A;  2YEO A;  1I6G A;  1DQ7 A;  5CY0 A; 
#chains in the Genus database with same CATH topology
 1JXC A;  2N69 A;  1L4V A;  2LJM A;  1NGE A;  3KOZ A;  5AQG A;  1MYN A;  1WWN A;  2YIO A;  1KV0 A;  3LDP A;  5FPE A;  2QWR A;  1JKZ A;  5AQJ A;  3QFP A;  2QW9 A;  3JXU A;  2V7Z A;  4HWI A;  4UAD E;  3C7N A;  3SF4 D;  1BA0 A;  1BUP A;  1ATR A;  1HJO A;  1TI5 A;  2ASC A;  1SN4 A;  1OMY A;  3GL1 A;  2KBJ A;  5AQR A;  5AQT A;  1VNA A;  3D2E A;  4FSV A;  2KSK A;  1I2V A;  1XRS B;  1B7D A;  1QQN A;  1QQO A;  2QWM A;  1GPS A;  2BRZ A;  1WT7 A;  2NY9 X;  5AR0 A;  5AQM A;  4V1D C;  3L6Q A;  1ZVG A;  1ZVE A;  5BPN A;  1ZYV A;  1JZA A;  3KOW A;  2E2F A;  5FPD A;  1BA1 A;  2QXL A;  5BN8 A;  2BUP A;  2GL1 A;  1GPT A;  4UJ0 A;  2YBR C;  2QWN A;  1NGC A;  2E3F A;  5AQW A;  1PE4 A;  5BPL A;  3FZK A;  3CW4 A;  2LT8 A;  5BPM A;  1BCG A;  1T7E A;  1S3X A;  1ZUT A;  1LQI A;  2MBK A;  3L56 A;  2M8B B;  4H5T A;  1NGB A;  2KBK A;  3E7R L;  2YIP A;  1I2U A;  5EVZ A;  2LR3 A;  1NGJ A;  1KAY A;  1SNB A;  1ZYW A;  3HSC A;  5AQP A;  4FL9 A;  3D2E B;  4H5V A;  1DKG D;  2YC1 C;  2G2K A;  2N66 A;  2QWO A;  3ATV A;  5AQK A;  3LDL A;  3D2F A;  4AEI A;  1FH3 A;  1KAZ A;  2KHO A;  1B3C A;  3QML A;  3KP0 A;  1JZB A;  2LI7 A;  4GNI A;  1ICA A;  1AHO A;  2ATB A;  3KOX A;  4AB0 A;  3GKU A;  3GDQ A;  3PSM A;  5EXW A;  1OZZ A;  5EX5 A;  4CQK A;  1BMR A;  5F2R A;  3R2V A;  2I61 A;  4IO8 A;  3KC6 A;  3KOY A;  5F1X A;  1NGA A;  4UAF E;  1P00 A;  2B68 A;  2E0H A;  2LY6 A;  1MR4 A;  2KBH A;  2LN8 A;  1KAX A;  3KP1 A;  5F0X A;  2NY8 X;  1NRA A;  1ZFU A;  2A7T A;  3C7N B;  1N4N A;  3FZL A;  3LDN A;  1C55 A;  1AYJ A;  3E7U X;  5AQZ A;  1ATS A;  1NE5 A;  2JDQ D;  5AQI A;  1YUW A;  2D56 A;  2VY6 A;  1T7B A;  2N2Q A;  5AQH A;  1NRB A;  3D2F B;  5AQF A;  2KJA A;  2SN3 A;  3L4I A;  1UGL A;  1C56 A;  4HHF A;  3FZH A;  2KPY A;  5KK4 A;  1NPI A;  2E8A A;  3IUC A;  4HE7 A;  2MN5 A;  3BK3 C;  1SN1 A;  2QWL A;  2E88 A;  3FE1 A;  1BRZ A;  3ATU A;  5AQY A;  4H5N A;  5AQL A;  3QI7 A;  1LQQ A;  1HX1 A;  1NGH A;  5EY4 A;  3QFU A;  1DJT A;  1NGD A;  3LDQ A;  2GMO A;  3CQX A;  1PX9 A;  2KYQ A;  1BK8 A;  1QQM A;  1T7A A;  1SEG A;  1PTX A;  2KGQ A;  5AQU A;  5AQS A;  5BN9 A;  2LKB A;  4H5W A;  3KHW A;  5FPN A;  3AY9 A;  2N2R A;  3FZF A;  5AQV A;  4KYP A;  2YIL A;  2QWQ A;  1T0Z A;  4KBO A;  5AQO A;  4UAE F;  5AQX A;  1NGF A;  5AQN A;  1ZU3 A;  1NH5 A;  1K8B A;  3M3Z A;  2B3C A;  1P0A A;  1HPM A;  1CHZ A;  1WMT A;  1NGG A;  1LQH A;  1POI A;  1VNB A;  2MZ0 A;  1I6F A;  2QWP A;  5AQQ A;  5FPM A;  2LY5 A;  1CN2 A;  4AAZ A;  2K35 A;  1T1T A;  2LJ7 A;  1NGI A;  3I33 A;  2E3G A;  3KVG A;  3LDO A;  2YEO A;  3FZM A;  4H5R A;  1I6G A;  3A8Y A;  1DQ7 A;  5CY0 A; 
#chains in the Genus database with same CATH homology
 1JXC A;  2N69 A;  1L4V A;  2LJM A;  1MYN A;  1WWN A;  1JKZ A;  1KV0 A;  1TI5 A;  2ASC A;  1SN4 A;  1OMY A;  2KBJ A;  1VNA A;  2KSK A;  1B7D A;  1GPS A;  2BRZ A;  1WT7 A;  2NY9 X;  4V1D C;  1ZVG A;  1ZVE A;  1ZYV A;  1JZA A;  2GL1 A;  1GPT A;  4UJ0 A;  2YBR C;  2E3F A;  1PE4 A;  2LT8 A;  1BCG A;  1T7E A;  1ZUT A;  1LQI A;  2M8B B;  2KBK A;  3E7R L;  1I2U A;  2LR3 A;  1ZYW A;  1SNB A;  2YC1 C;  2N66 A;  1FH3 A;  4AEI A;  1B3C A;  1JZB A;  2LI7 A;  1ICA A;  1AHO A;  2ATB A;  4AB0 A;  3PSM A;  1BMR A;  1OZZ A;  2I61 A;  1P00 A;  2B68 A;  2E0H A;  2LY6 A;  1MR4 A;  2KBH A;  2NY8 X;  1NRA A;  1ZFU A;  2A7T A;  1N4N A;  1C55 A;  1AYJ A;  3E7U X;  1NE5 A;  1T7B A;  2N2Q A;  1NRB A;  2KJA A;  2SN3 A;  1C56 A;  4HHF A;  2KPY A;  5KK4 A;  1NPI A;  4HE7 A;  1SN1 A;  1BRZ A;  1LQQ A;  1DJT A;  1PX9 A;  2KYQ A;  1BK8 A;  1T7A A;  1SEG A;  1PTX A;  2KGQ A;  2LKB A;  2N2R A;  4CQK A;  1I2V A;  4KYP A;  1T0Z A;  1ZU3 A;  1NH5 A;  2B3C A;  1P0A A;  1CHZ A;  1WMT A;  1LQH A;  2MZ0 A;  1VNB A;  1I6F A;  1CN2 A;  2LY5 A;  4AAZ A;  1T1T A;  2LJ7 A;  2E3G A;  2YEO A;  1I6G A;  1DQ7 A;  5CY0 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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