1P0AA

Nmr structure of etd135, mutant of the antifungal defensin ard1 from archaeoprepona demophon
Total Genus 8
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
8
sequence length
44
structure length
44
Chain Sequence
DKLIGSCVWGAVNYTSNCNAECKRRGYKGGHCGSFLNVNCWCET
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Lead optimization of antifungal peptides with 3D NMR structures analysis.
pubmed doi rcsb
molecule tags Antifungal protein
source organism Archaeoprepona demophon
molecule keywords DEFENSIN ARD1
total genus 8
structure length 44
sequence length 44
ec nomenclature
pdb deposition date 2003-04-10
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.30.10 Alpha Beta 2-Layer Sandwich Defensin A-like Knottin, scorpion toxin-like 1p0aA00
1JZAA 1ZUTA 2I61A 1B7DA 4HHFA 1ZYVA 1ZFUA 2ATBA 1SN4A 1SN1A 1VNBA 2LJMA 1I6FA 1DQ7A 1ZYWA 2KBKA 1CHZA 1MR4A 1L4VA 1LQIA 2E0HA 1P0AA 1T1TA 2E3FA 4CQKA 1BRZA 2B68A 2KBHA 2NY9X 1OMYA 2KGQA 1FH3A 1KV0A 4V1DC 3E7UX 4KYPA 1OZZA 2M8BB 2N69A 2LY5A 1PTXA 1NH5A 1SNBA 2KBJA 2GL1A 1JKZA 1MYNA 1N4NA 1TI5A 1C55A 2KSKA 1BK8A 1GPSA 1P00A 2ASCA 5CY0A 1JXCA 2LJ7A 2SN3A 2LT8A 1SEGA 1PX9A 1B3CA 2N66A 2LY6A 1ZVGA 1NRBA 3E7RL 2BRZA 1DJTA 1NE5A 1T7EA 2N2RA 2YEOA 2LI7A 1GPTA 1WT7A 1ICAA 2N2QA 2B3CA 1BCGA 4AB0A 1I6GA 4AAZA 1I2UA 1ZU3A 1WWNA 1AHOA 1CN2A 1ZVEA 2LKBA 1VNAA 2KJAA 2A7TA 2KYQA 5KK4A 4HE7A 1JZBA 1BMRA 4UJ0A 3PSMA 1C56A 1I2VA 2KPYA 1T7AA 1T0ZA 2YBRC 1PE4A 2LR3A 1WMTA 1AYJA 1LQHA 2NY8X 2YC1C 1NPIA 1T7BA 4AEIA 1LQQA 2MZ0A 1NRAA 2E3GA
chains in the Genus database with same CATH superfamily
1JZAA 3D2EB 3ATUA 3KP1A 1KAZA 2QWLA 1UGLA 3LDPA 1ZUTA 2I61A 1B7DA 1NGEA 2YIOA 3QMLA 1ZYVA 4HHFA 3QFPA 5F1XA 1ATRA 1ZFUA 2ATBA 3GDQA 4H5RA 5AQKA 1DKGD 1SN4A 3QI7A 1SN1A 5AQMA 1VNBA 5AQQA 1S3XA 2LJMA 1ATSA 1I6FA 3AY9A 3LDOA 1NGHA 3GL1A 5BN9A 1DQ7A 1ZYWA 2KBKA 1CHZA 1MR4A 1L4VA 3FZLA 1LQIA 2E0HA 1P0AA 1T1TA 2E3FA 4CQKA 3KOYA 3C7NB 4FSVA 1BRZA 3KOWA 2B68A 5AQOA 2KBHA 2NY9X 2QWQA 1OMYA 2KGQA 1FH3A 5AQHA 1KV0A 1QQMA 1HX1A 3C7NA 4V1DC 5EVZA 3E7UX 4KYPA 1OZZA 2M8BB 5FPNA 2QXLA 3A8YA 2N69A 3KVGA 2LY5A 3D2EA 1PTXA 1NH5A 1SNBA 2KBJA 1NGDA 2GL1A 2QWRA 3KC6A 4GNIA 1JKZA 2QWNA 1MYNA 1N4NA 1TI5A 4KBOA 4UADE 5AQTA 1C55A 2KSKA 2D56A 3KOXA 5AQIA 1BK8A 1P00A 1NGAA 2ASCA 3FZKA 5CY0A 1GPSA 2BUPA 1JXCA 4H5TA 1HJOA 2MN5A 4H5NA 5AR0A 2LJ7A 2SN3A 2VY6A 3HSCA 1SEGA 1PX9A 2LT8A 2K35A 3LDLA 2N66A 2QWPA 2LY6A 1B3CA 2YIPA 2E2FA 1ZVGA 3L6QA 5FPDA 1K8BA 1NRBA 3E7RL 1DJTA 2BRZA 1BUPA 5EXWA 1XRSB 1NE5A 3CW4A 1NGIA 1T7EA 1BA0A 1NGJA 5BN8A 5F0XA 1KAYA 1QQNA 2N2RA 2LI7A 2YEOA 2YILA 3LDQA 3QFUA 2KHOA 5AQNA 5F2RA 3KHWA 1GPTA 1WT7A 5AQLA 5AQRA 1ICAA 5FPEA 2N2QA 1YUWA 2B3CA 1BCGA 2G2KA 2E8AA 5BPLA 4H5WA 2MBKA 4AB0A 4AAZA 1I6GA 2LN8A 1I2UA 1ZU3A 1WWNA 3ATVA 1AHOA 1CN2A 1ZVEA 1HPMA 2LKBA 1VNAA 3FZFA 2KJAA 2A7TA 2KYQA 3BK3C 5KK4A 4HE7A 1KAXA 5FPMA 3FZHA 1JZBA 5AQVA 2QW9A 4UAEF 5AQPA 5AQJA 1BMRA 4UJ0A 3PSMA 5AQUA 5AQXA 3D2FB 1C56A 1NGCA 1I2VA 3KP0A 3FE1A 5AQSA 3KOZA 3GKUA 2JDQD 4UAFE 3FZMA 5AQFA 2KPYA 3D2FA 5AQGA 1T7AA 1T0ZA 3LDNA 1NGBA 1NGGA 2YBRC 1PE4A 5EY4A 2LR3A 1WMTA 5AQYA 2QWOA 5BPMA 1AYJA 1LQHA 2NY8X 5EX5A 2QWMA 2YC1C 3SF4D 2V7ZA 1NPIA 5AQZA 5BPNA 1T7BA 4AEIA 3R2VA 4IO8A 1NGFA 3JXUA 4H5VA 4HWIA 1QQOA 1LQQA 1POIA 3CQXA 2MZ0A 3L56A 3M3ZA 4FL9A 3L4IA 1BA1A 2GMOA 1NRAA 3IUCA 5AQWA 3I33A 2E3GA 2E88A
chains in the Genus database with same CATH topology
1JZAA 1ZUTA 2I61A 1B7DA 4HHFA 1ZYVA 1ZFUA 2ATBA 1SN4A 1SN1A 1VNBA 2LJMA 1I6FA 1DQ7A 1ZYWA 2KBKA 1CHZA 1MR4A 1L4VA 1LQIA 2E0HA 1P0AA 1T1TA 2E3FA 4CQKA 1BRZA 2B68A 2KBHA 2NY9X 1OMYA 2KGQA 1FH3A 1KV0A 4V1DC 3E7UX 4KYPA 1OZZA 2M8BB 2N69A 2LY5A 1PTXA 1NH5A 1SNBA 2KBJA 2GL1A 1JKZA 1MYNA 1N4NA 1TI5A 1C55A 2KSKA 1BK8A 1GPSA 1P00A 2ASCA 5CY0A 1JXCA 2LJ7A 2SN3A 2LT8A 1SEGA 1PX9A 1B3CA 2N66A 2LY6A 1ZVGA 1NRBA 3E7RL 2BRZA 1DJTA 1NE5A 1T7EA 2N2RA 2YEOA 2LI7A 1GPTA 1WT7A 1ICAA 2N2QA 2B3CA 1BCGA 4AB0A 1I6GA 4AAZA 1I2UA 1ZU3A 1WWNA 1AHOA 1CN2A 1ZVEA 2LKBA 1VNAA 2KJAA 2A7TA 2KYQA 5KK4A 4HE7A 1JZBA 1BMRA 4UJ0A 3PSMA 1C56A 1I2VA 2KPYA 1T7AA 1T0ZA 2YBRC 1PE4A 2LR3A 1WMTA 1AYJA 1LQHA 2NY8X 2YC1C 1NPIA 1T7BA 4AEIA 1LQQA 2MZ0A 1NRAA 2E3GA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1JZA A;  1ZUT A;  2I61 A;  1B7D A;  4HHF A;  1ZYV A;  1ZFU A;  2ATB A;  1SN4 A;  1SN1 A;  1VNB A;  2LJM A;  1I6F A;  1DQ7 A;  1ZYW A;  2KBK A;  1CHZ A;  1MR4 A;  1L4V A;  1LQI A;  2E0H A;  1P0A A;  1T1T A;  2E3F A;  4CQK A;  1BRZ A;  2B68 A;  2KBH A;  2NY9 X;  1OMY A;  2KGQ A;  1FH3 A;  1KV0 A;  4V1D C;  3E7U X;  4KYP A;  1OZZ A;  2M8B B;  2N69 A;  2LY5 A;  1PTX A;  1NH5 A;  1SNB A;  2KBJ A;  2GL1 A;  1JKZ A;  1MYN A;  1N4N A;  1TI5 A;  1C55 A;  2KSK A;  1BK8 A;  1GPS A;  1P00 A;  2ASC A;  5CY0 A;  1JXC A;  2LJ7 A;  2SN3 A;  2LT8 A;  1SEG A;  1PX9 A;  1B3C A;  2N66 A;  2LY6 A;  1ZVG A;  1NRB A;  3E7R L;  2BRZ A;  1DJT A;  1NE5 A;  1T7E A;  2N2R A;  2YEO A;  2LI7 A;  1GPT A;  1WT7 A;  1ICA A;  2N2Q A;  2B3C A;  1BCG A;  4AB0 A;  1I6G A;  4AAZ A;  1I2U A;  1ZU3 A;  1WWN A;  1AHO A;  1CN2 A;  1ZVE A;  2LKB A;  1VNA A;  2KJA A;  2A7T A;  2KYQ A;  5KK4 A;  4HE7 A;  1JZB A;  1BMR A;  4UJ0 A;  3PSM A;  1C56 A;  1I2V A;  2KPY A;  1T7A A;  1T0Z A;  2YBR C;  1PE4 A;  2LR3 A;  1WMT A;  1AYJ A;  1LQH A;  2NY8 X;  2YC1 C;  1NPI A;  1T7B A;  4AEI A;  1LQQ A;  2MZ0 A;  1NRA A;  2E3G A; 
#chains in the Genus database with same CATH topology
 1JZA A;  3D2E B;  3ATU A;  3KP1 A;  1KAZ A;  2QWL A;  1UGL A;  3LDP A;  1ZUT A;  2I61 A;  1B7D A;  1NGE A;  2YIO A;  3QML A;  1ZYV A;  4HHF A;  3QFP A;  5F1X A;  1ATR A;  1ZFU A;  2ATB A;  3GDQ A;  4H5R A;  5AQK A;  1DKG D;  1SN4 A;  3QI7 A;  1SN1 A;  5AQM A;  1VNB A;  5AQQ A;  1S3X A;  2LJM A;  1ATS A;  1I6F A;  3AY9 A;  3LDO A;  1NGH A;  3GL1 A;  5BN9 A;  1DQ7 A;  1ZYW A;  2KBK A;  1CHZ A;  1MR4 A;  1L4V A;  3FZL A;  1LQI A;  2E0H A;  1P0A A;  1T1T A;  2E3F A;  4CQK A;  3KOY A;  3C7N B;  4FSV A;  1BRZ A;  3KOW A;  2B68 A;  5AQO A;  2KBH A;  2NY9 X;  2QWQ A;  1OMY A;  2KGQ A;  1FH3 A;  5AQH A;  1KV0 A;  1QQM A;  1HX1 A;  3C7N A;  4V1D C;  5EVZ A;  3E7U X;  4KYP A;  1OZZ A;  2M8B B;  5FPN A;  2QXL A;  3A8Y A;  2N69 A;  3KVG A;  2LY5 A;  3D2E A;  1PTX A;  1NH5 A;  1SNB A;  2KBJ A;  1NGD A;  2GL1 A;  2QWR A;  3KC6 A;  4GNI A;  1JKZ A;  2QWN A;  1MYN A;  1N4N A;  1TI5 A;  4KBO A;  4UAD E;  5AQT A;  1C55 A;  2KSK A;  2D56 A;  3KOX A;  5AQI A;  1BK8 A;  1P00 A;  1NGA A;  2ASC A;  3FZK A;  5CY0 A;  1GPS A;  2BUP A;  1JXC A;  4H5T A;  1HJO A;  2MN5 A;  4H5N A;  5AR0 A;  2LJ7 A;  2SN3 A;  2VY6 A;  3HSC A;  1SEG A;  1PX9 A;  2LT8 A;  2K35 A;  3LDL A;  2N66 A;  2QWP A;  2LY6 A;  1B3C A;  2YIP A;  2E2F A;  1ZVG A;  3L6Q A;  5FPD A;  1K8B A;  1NRB A;  3E7R L;  1DJT A;  2BRZ A;  1BUP A;  5EXW A;  1XRS B;  1NE5 A;  3CW4 A;  1NGI A;  1T7E A;  1BA0 A;  1NGJ A;  5BN8 A;  5F0X A;  1KAY A;  1QQN A;  2N2R A;  2LI7 A;  2YEO A;  2YIL A;  3LDQ A;  3QFU A;  2KHO A;  5AQN A;  5F2R A;  3KHW A;  1GPT A;  1WT7 A;  5AQL A;  5AQR A;  1ICA A;  5FPE A;  2N2Q A;  1YUW A;  2B3C A;  1BCG A;  2G2K A;  2E8A A;  5BPL A;  4H5W A;  2MBK A;  4AB0 A;  4AAZ A;  1I6G A;  2LN8 A;  1I2U A;  1ZU3 A;  1WWN A;  3ATV A;  1AHO A;  1CN2 A;  1ZVE A;  1HPM A;  2LKB A;  1VNA A;  3FZF A;  2KJA A;  2A7T A;  2KYQ A;  3BK3 C;  5KK4 A;  4HE7 A;  1KAX A;  5FPM A;  3FZH A;  1JZB A;  5AQV A;  2QW9 A;  4UAE F;  5AQP A;  5AQJ A;  1BMR A;  4UJ0 A;  3PSM A;  5AQU A;  5AQX A;  3D2F B;  1C56 A;  1NGC A;  1I2V A;  3KP0 A;  3FE1 A;  5AQS A;  3KOZ A;  3GKU A;  2JDQ D;  4UAF E;  3FZM A;  5AQF A;  2KPY A;  3D2F A;  5AQG A;  1T7A A;  1T0Z A;  3LDN A;  1NGB A;  1NGG A;  2YBR C;  1PE4 A;  5EY4 A;  2LR3 A;  1WMT A;  5AQY A;  2QWO A;  5BPM A;  1AYJ A;  1LQH A;  2NY8 X;  5EX5 A;  2QWM A;  2YC1 C;  3SF4 D;  2V7Z A;  1NPI A;  5AQZ A;  5BPN A;  1T7B A;  4AEI A;  3R2V A;  4IO8 A;  1NGF A;  3JXU A;  4H5V A;  4HWI A;  1QQO A;  1LQQ A;  1POI A;  3CQX A;  2MZ0 A;  3L56 A;  3M3Z A;  4FL9 A;  3L4I A;  1BA1 A;  2GMO A;  1NRA A;  3IUC A;  5AQW A;  3I33 A;  2E3G A;  2E88 A; 
#chains in the Genus database with same CATH homology
 1JZA A;  1ZUT A;  2I61 A;  1B7D A;  4HHF A;  1ZYV A;  1ZFU A;  2ATB A;  1SN4 A;  1SN1 A;  1VNB A;  2LJM A;  1I6F A;  1DQ7 A;  1ZYW A;  2KBK A;  1CHZ A;  1MR4 A;  1L4V A;  1LQI A;  2E0H A;  1P0A A;  1T1T A;  2E3F A;  4CQK A;  1BRZ A;  2B68 A;  2KBH A;  2NY9 X;  1OMY A;  2KGQ A;  1FH3 A;  1KV0 A;  4V1D C;  3E7U X;  4KYP A;  1OZZ A;  2M8B B;  2N69 A;  2LY5 A;  1PTX A;  1NH5 A;  1SNB A;  2KBJ A;  2GL1 A;  1JKZ A;  1MYN A;  1N4N A;  1TI5 A;  1C55 A;  2KSK A;  1BK8 A;  1GPS A;  1P00 A;  2ASC A;  5CY0 A;  1JXC A;  2LJ7 A;  2SN3 A;  2LT8 A;  1SEG A;  1PX9 A;  1B3C A;  2N66 A;  2LY6 A;  1ZVG A;  1NRB A;  3E7R L;  2BRZ A;  1DJT A;  1NE5 A;  1T7E A;  2N2R A;  2YEO A;  2LI7 A;  1GPT A;  1WT7 A;  1ICA A;  2N2Q A;  2B3C A;  1BCG A;  4AB0 A;  1I6G A;  4AAZ A;  1I2U A;  1ZU3 A;  1WWN A;  1AHO A;  1CN2 A;  1ZVE A;  2LKB A;  1VNA A;  2KJA A;  2A7T A;  2KYQ A;  5KK4 A;  4HE7 A;  1JZB A;  1BMR A;  4UJ0 A;  3PSM A;  1C56 A;  1I2V A;  2KPY A;  1T7A A;  1T0Z A;  2YBR C;  1PE4 A;  2LR3 A;  1WMT A;  1AYJ A;  1LQH A;  2NY8 X;  2YC1 C;  1NPI A;  1T7B A;  4AEI A;  1LQQ A;  2MZ0 A;  1NRA A;  2E3G A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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