1VNBA

Proton nuclear magnetic resonance and distance geometry(slash)simulated annealing studies on the variant-1 neurotoxin from the new world scorpion centruroides sculpturatus ewing
Total Genus 5
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
5
sequence length
65
structure length
65
Chain Sequence
KEGYLVKKSDGCKYDCFWLGKNEHCNTECKAKNQGGSYGYCYAFACWCEGLPESTPTYPLPNKSC
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Proton nuclear magnetic resonance and distance geometry/simulated annealing studies on the variant-1 neurotoxin from the New World scorpion Centruroides sculpturatus Ewing.
pubmed doi rcsb
molecule tags Neurotoxin
source organism Centruroides sculpturatus
molecule keywords NEUROTOXIN
total genus 5
structure length 65
sequence length 65
ec nomenclature
pdb deposition date 1993-10-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00537 Toxin_3 Scorpion toxin-like domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.30.10 Alpha Beta 2-Layer Sandwich Defensin A-like Knottin, scorpion toxin-like 1vnbA00
2N2QA 2LJMA 1N4NA 1BCGA 3PSMA 1SNBA 1TI5A 1BK8A 1CHZA 1L4VA 4HE7A 2N2RA 1SN1A 1ZFUA 4UJ0A 4AEIA 2ASCA 1T1TA 2KBKA 1ICAA 1C55A 1MYNA 2KYQA 1B3CA 1PTXA 1NH5A 2KBJA 1JZBA 1ZYWA 1I6FA 1CN2A 2YC1C 1I6GA 1VNAA 4AB0A 2LT8A 1ZYVA 2NY9X 1SEGA 2LR3A 1GPSA 2A7TA 1BMRA 2KBHA 2B68A 1ZVGA 2M8BB 1T7BA 2LY6A 2NY8X 1P0AA 2YBRC 1DJTA 1NRBA 1GPTA 1NRAA 1WWNA 4V1DC 2SN3A 1OZZA 1C56A 2KSKA 4CQKA 2E3FA 4HHFA 2N66A 2LJ7A 1JKZA 2BRZA 2MZ0A 2KJAA 1OMYA 2N69A 2B3CA 2KGQA 2YEOA 1B7DA 1I2UA 1KV0A 2LKBA 1SN4A 2LY5A 1LQHA 1P00A 1PE4A 1DQ7A 2LI7A 1ZVEA 1AYJA 5CY0A 1VNBA 1T7AA 2E0HA 5KK4A 1JZAA 1JXCA 1WT7A 1T0ZA 2GL1A 1MR4A 1NE5A 2KPYA 3E7UX 1NPIA 1PX9A 4AAZA 1ZU3A 1BRZA 1FH3A 1WMTA 2I61A 1AHOA 3E7RL 1LQIA 1T7EA 2ATBA 2E3GA 1I2VA 1LQQA 1ZUTA 4KYPA
chains in the Genus database with same CATH superfamily
4H5RA 2N2QA 3QMLA 2LJMA 1N4NA 3R2VA 1BCGA 1POIA 3PSMA 3FZKA 1SNBA 3FZHA 1KAZA 3KP0A 1TI5A 1BK8A 5F1XA 3A8YA 3ATVA 3FZMA 1CHZA 5FPNA 1NGCA 1L4VA 4HE7A 2N2RA 1SN1A 4FSVA 1ZFUA 3GL1A 3LDQA 3KHWA 3I33A 2YILA 4UJ0A 3KOYA 4AEIA 5AQNA 1QQOA 2ASCA 1T1TA 1HX1A 1HPMA 2KBKA 3D2EA 4UAFE 3QFPA 1ICAA 3LDOA 4H5VA 1C55A 5AQQA 1MYNA 2KYQA 1B3CA 2G2KA 1PTXA 1YUWA 2V7ZA 1NH5A 2JDQD 5AQZA 2QW9A 2KBJA 1JZBA 1ZYWA 3KOXA 1I6FA 5EVZA 1CN2A 2YC1C 1I6GA 1VNAA 4HWIA 2QXLA 2LT8A 1ZYVA 2NY9X 4AB0A 1SEGA 2LN8A 1XRSB 3CQXA 3ATUA 2LR3A 1GPSA 2A7TA 1K8BA 3M3ZA 3IUCA 1BMRA 2KBHA 2B68A 2YIOA 1NGAA 5BN8A 5FPEA 1ZVGA 2VY6A 5AQYA 1NGHA 1T7BA 2M8BB 3L56A 3BK3C 2LY6A 2NY8X 1P0AA 3D2FB 3GKUA 2QWMA 2YBRC 5AR0A 3C7NB 1DJTA 5AQWA 3HSCA 1NRBA 1GPTA 1ATRA 1NRAA 1WWNA 2E88A 4KBOA 2MN5A 4V1DC 2SN3A 1ATSA 1OZZA 4FL9A 5AQXA 1C56A 1NGEA 2KSKA 3AY9A 3FZFA 4CQKA 2E3FA 2KHOA 4HHFA 2N66A 2LJ7A 1JKZA 2BRZA 2MZ0A 3L6QA 1BUPA 2KJAA 4UADE 3CW4A 5AQOA 1OMYA 2N69A 1NGFA 1NGBA 2B3CA 2KGQA 3FE1A 5BPMA 2YEOA 1B7DA 5AQTA 4H5WA 3GDQA 1NGDA 5AQGA 1DKGD 1KV0A 4UAEF 1I2UA 2LKBA 1SN4A 2LY5A 1LQHA 5AQRA 1P00A 2QWOA 1PE4A 1KAYA 2QWQA 2YIPA 3KP1A 5AQLA 3D2EB 5AQVA 5EXWA 1DQ7A 2LI7A 1ZVEA 2QWNA 5AQFA 5CY0A 1AYJA 1VNBA 1T7AA 2E0HA 5AQPA 1JZAA 5KK4A 1JXCA 3LDNA 1WT7A 2QWLA 1T0ZA 3D2FA 5FPDA 2GL1A 1MR4A 1NE5A 3JXUA 3QFUA 5BPNA 2KPYA 3E7UX 3FZLA 5AQSA 2E8AA 5AQMA 5AQUA 3SF4D 4H5TA 5F0XA 2QWPA 1NPIA 1PX9A 3KC6A 4AAZA 5FPMA 2BUPA 1KAXA 2QWRA 3LDPA 1ZU3A 2K35A 3KOZA 1BRZA 1FH3A 1NGGA 1WMTA 2I61A 5BPLA 1BA1A 1AHOA 3E7RL 5AQJA 1LQIA 5F2RA 2MBKA 1T7EA 2ATBA 5AQKA 4GNIA 3QI7A 1NGIA 2E2FA 4H5NA 5AQHA 5AQIA 2E3GA 1QQMA 3KVGA 2D56A 5EY4A 1I2VA 1LQQA 1QQNA 2GMOA 1NGJA 1HJOA 1UGLA 4IO8A 1BA0A 3KOWA 3LDLA 1ZUTA 1S3XA 5BN9A 3C7NA 5EX5A 3L4IA 4KYPA
chains in the Genus database with same CATH topology
2N2QA 2LJMA 1N4NA 1BCGA 3PSMA 1SNBA 1TI5A 1BK8A 1CHZA 1L4VA 4HE7A 2N2RA 1SN1A 1ZFUA 4UJ0A 4AEIA 2ASCA 1T1TA 2KBKA 1ICAA 1C55A 1MYNA 2KYQA 1B3CA 1PTXA 1NH5A 2KBJA 1JZBA 1ZYWA 1I6FA 1CN2A 2YC1C 1I6GA 1VNAA 4AB0A 2LT8A 1ZYVA 2NY9X 1SEGA 2LR3A 1GPSA 2A7TA 1BMRA 2KBHA 2B68A 1ZVGA 2M8BB 1T7BA 2LY6A 2NY8X 1P0AA 2YBRC 1DJTA 1NRBA 1GPTA 1NRAA 1WWNA 4V1DC 2SN3A 1OZZA 1C56A 2KSKA 4CQKA 2E3FA 4HHFA 2N66A 2LJ7A 1JKZA 2BRZA 2MZ0A 2KJAA 1OMYA 2N69A 2B3CA 2KGQA 2YEOA 1B7DA 1I2UA 1KV0A 2LKBA 1SN4A 2LY5A 1LQHA 1P00A 1PE4A 1DQ7A 2LI7A 1ZVEA 1AYJA 5CY0A 1VNBA 1T7AA 2E0HA 5KK4A 1JZAA 1JXCA 1WT7A 1T0ZA 2GL1A 1MR4A 1NE5A 2KPYA 3E7UX 1NPIA 1PX9A 4AAZA 1ZU3A 1BRZA 1FH3A 1WMTA 2I61A 1AHOA 3E7RL 1LQIA 1T7EA 2ATBA 2E3GA 1I2VA 1LQQA 1ZUTA 4KYPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2N2Q A;  2LJM A;  1N4N A;  1BCG A;  3PSM A;  1SNB A;  1TI5 A;  1BK8 A;  1CHZ A;  1L4V A;  4HE7 A;  2N2R A;  1SN1 A;  1ZFU A;  4UJ0 A;  4AEI A;  2ASC A;  1T1T A;  2KBK A;  1ICA A;  1C55 A;  1MYN A;  2KYQ A;  1B3C A;  1PTX A;  1NH5 A;  2KBJ A;  1JZB A;  1ZYW A;  1I6F A;  1CN2 A;  2YC1 C;  1I6G A;  1VNA A;  4AB0 A;  2LT8 A;  1ZYV A;  2NY9 X;  1SEG A;  2LR3 A;  1GPS A;  2A7T A;  1BMR A;  2KBH A;  2B68 A;  1ZVG A;  2M8B B;  1T7B A;  2LY6 A;  2NY8 X;  1P0A A;  2YBR C;  1DJT A;  1NRB A;  1GPT A;  1NRA A;  1WWN A;  4V1D C;  2SN3 A;  1OZZ A;  1C56 A;  2KSK A;  4CQK A;  2E3F A;  4HHF A;  2N66 A;  2LJ7 A;  1JKZ A;  2BRZ A;  2MZ0 A;  2KJA A;  1OMY A;  2N69 A;  2B3C A;  2KGQ A;  2YEO A;  1B7D A;  1I2U A;  1KV0 A;  2LKB A;  1SN4 A;  2LY5 A;  1LQH A;  1P00 A;  1PE4 A;  1DQ7 A;  2LI7 A;  1ZVE A;  1AYJ A;  5CY0 A;  1VNB A;  1T7A A;  2E0H A;  5KK4 A;  1JZA A;  1JXC A;  1WT7 A;  1T0Z A;  2GL1 A;  1MR4 A;  1NE5 A;  2KPY A;  3E7U X;  1NPI A;  1PX9 A;  4AAZ A;  1ZU3 A;  1BRZ A;  1FH3 A;  1WMT A;  2I61 A;  1AHO A;  3E7R L;  1LQI A;  1T7E A;  2ATB A;  2E3G A;  1I2V A;  1LQQ A;  1ZUT A;  4KYP A; 
#chains in the Genus database with same CATH topology
 4H5R A;  2N2Q A;  3QML A;  2LJM A;  1N4N A;  3R2V A;  1BCG A;  1POI A;  3PSM A;  3FZK A;  1SNB A;  3FZH A;  1KAZ A;  3KP0 A;  1TI5 A;  1BK8 A;  5F1X A;  3A8Y A;  3ATV A;  3FZM A;  1CHZ A;  5FPN A;  1NGC A;  1L4V A;  4HE7 A;  2N2R A;  1SN1 A;  4FSV A;  1ZFU A;  3GL1 A;  3LDQ A;  3KHW A;  3I33 A;  2YIL A;  4UJ0 A;  3KOY A;  4AEI A;  5AQN A;  1QQO A;  2ASC A;  1T1T A;  1HX1 A;  1HPM A;  2KBK A;  3D2E A;  4UAF E;  3QFP A;  1ICA A;  3LDO A;  4H5V A;  1C55 A;  5AQQ A;  1MYN A;  2KYQ A;  1B3C A;  2G2K A;  1PTX A;  1YUW A;  2V7Z A;  1NH5 A;  2JDQ D;  5AQZ A;  2QW9 A;  2KBJ A;  1JZB A;  1ZYW A;  3KOX A;  1I6F A;  5EVZ A;  1CN2 A;  2YC1 C;  1I6G A;  1VNA A;  4HWI A;  2QXL A;  2LT8 A;  1ZYV A;  2NY9 X;  4AB0 A;  1SEG A;  2LN8 A;  1XRS B;  3CQX A;  3ATU A;  2LR3 A;  1GPS A;  2A7T A;  1K8B A;  3M3Z A;  3IUC A;  1BMR A;  2KBH A;  2B68 A;  2YIO A;  1NGA A;  5BN8 A;  5FPE A;  1ZVG A;  2VY6 A;  5AQY A;  1NGH A;  1T7B A;  2M8B B;  3L56 A;  3BK3 C;  2LY6 A;  2NY8 X;  1P0A A;  3D2F B;  3GKU A;  2QWM A;  2YBR C;  5AR0 A;  3C7N B;  1DJT A;  5AQW A;  3HSC A;  1NRB A;  1GPT A;  1ATR A;  1NRA A;  1WWN A;  2E88 A;  4KBO A;  2MN5 A;  4V1D C;  2SN3 A;  1ATS A;  1OZZ A;  4FL9 A;  5AQX A;  1C56 A;  1NGE A;  2KSK A;  3AY9 A;  3FZF A;  4CQK A;  2E3F A;  2KHO A;  4HHF A;  2N66 A;  2LJ7 A;  1JKZ A;  2BRZ A;  2MZ0 A;  3L6Q A;  1BUP A;  2KJA A;  4UAD E;  3CW4 A;  5AQO A;  1OMY A;  2N69 A;  1NGF A;  1NGB A;  2B3C A;  2KGQ A;  3FE1 A;  5BPM A;  2YEO A;  1B7D A;  5AQT A;  4H5W A;  3GDQ A;  1NGD A;  5AQG A;  1DKG D;  1KV0 A;  4UAE F;  1I2U A;  2LKB A;  1SN4 A;  2LY5 A;  1LQH A;  5AQR A;  1P00 A;  2QWO A;  1PE4 A;  1KAY A;  2QWQ A;  2YIP A;  3KP1 A;  5AQL A;  3D2E B;  5AQV A;  5EXW A;  1DQ7 A;  2LI7 A;  1ZVE A;  2QWN A;  5AQF A;  5CY0 A;  1AYJ A;  1VNB A;  1T7A A;  2E0H A;  5AQP A;  1JZA A;  5KK4 A;  1JXC A;  3LDN A;  1WT7 A;  2QWL A;  1T0Z A;  3D2F A;  5FPD A;  2GL1 A;  1MR4 A;  1NE5 A;  3JXU A;  3QFU A;  5BPN A;  2KPY A;  3E7U X;  3FZL A;  5AQS A;  2E8A A;  5AQM A;  5AQU A;  3SF4 D;  4H5T A;  5F0X A;  2QWP A;  1NPI A;  1PX9 A;  3KC6 A;  4AAZ A;  5FPM A;  2BUP A;  1KAX A;  2QWR A;  3LDP A;  1ZU3 A;  2K35 A;  3KOZ A;  1BRZ A;  1FH3 A;  1NGG A;  1WMT A;  2I61 A;  5BPL A;  1BA1 A;  1AHO A;  3E7R L;  5AQJ A;  1LQI A;  5F2R A;  2MBK A;  1T7E A;  2ATB A;  5AQK A;  4GNI A;  3QI7 A;  1NGI A;  2E2F A;  4H5N A;  5AQH A;  5AQI A;  2E3G A;  1QQM A;  3KVG A;  2D56 A;  5EY4 A;  1I2V A;  1LQQ A;  1QQN A;  2GMO A;  1NGJ A;  1HJO A;  1UGL A;  4IO8 A;  1BA0 A;  3KOW A;  3LDL A;  1ZUT A;  1S3X A;  5BN9 A;  3C7N A;  5EX5 A;  3L4I A;  4KYP A; 
#chains in the Genus database with same CATH homology
 2N2Q A;  2LJM A;  1N4N A;  1BCG A;  3PSM A;  1SNB A;  1TI5 A;  1BK8 A;  1CHZ A;  1L4V A;  4HE7 A;  2N2R A;  1SN1 A;  1ZFU A;  4UJ0 A;  4AEI A;  2ASC A;  1T1T A;  2KBK A;  1ICA A;  1C55 A;  1MYN A;  2KYQ A;  1B3C A;  1PTX A;  1NH5 A;  2KBJ A;  1JZB A;  1ZYW A;  1I6F A;  1CN2 A;  2YC1 C;  1I6G A;  1VNA A;  4AB0 A;  2LT8 A;  1ZYV A;  2NY9 X;  1SEG A;  2LR3 A;  1GPS A;  2A7T A;  1BMR A;  2KBH A;  2B68 A;  1ZVG A;  2M8B B;  1T7B A;  2LY6 A;  2NY8 X;  1P0A A;  2YBR C;  1DJT A;  1NRB A;  1GPT A;  1NRA A;  1WWN A;  4V1D C;  2SN3 A;  1OZZ A;  1C56 A;  2KSK A;  4CQK A;  2E3F A;  4HHF A;  2N66 A;  2LJ7 A;  1JKZ A;  2BRZ A;  2MZ0 A;  2KJA A;  1OMY A;  2N69 A;  2B3C A;  2KGQ A;  2YEO A;  1B7D A;  1I2U A;  1KV0 A;  2LKB A;  1SN4 A;  2LY5 A;  1LQH A;  1P00 A;  1PE4 A;  1DQ7 A;  2LI7 A;  1ZVE A;  1AYJ A;  5CY0 A;  1VNB A;  1T7A A;  2E0H A;  5KK4 A;  1JZA A;  1JXC A;  1WT7 A;  1T0Z A;  2GL1 A;  1MR4 A;  1NE5 A;  2KPY A;  3E7U X;  1NPI A;  1PX9 A;  4AAZ A;  1ZU3 A;  1BRZ A;  1FH3 A;  1WMT A;  2I61 A;  1AHO A;  3E7R L;  1LQI A;  1T7E A;  2ATB A;  2E3G A;  1I2V A;  1LQQ A;  1ZUT A;  4KYP A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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