1ZU3A

Crystal structure of mutant k8a of scorpion alpha-like neurotoxin bmk m1 from buthus martensii karsch
Total Genus 15
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
15
sequence length
64
structure length
64
Chain Sequence
VRDAYIAAPHNCVYECARNEYCNDLCTKNGAKSGYCQWVGKYGNGCWCIELPDNVPIRVPGKCH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Toxin
source organism Mesobuthus martensii
publication title Structural basis for the voltage-gated Na+ channel selectivity of the scorpion alpha-like toxin BmK M1
pubmed doi rcsb
molecule keywords Alpha-like neurotoxin BmK-I
total genus 15
structure length 64
sequence length 64
ec nomenclature
pdb deposition date 2005-05-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00537 Toxin_3 Scorpion toxin-like domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.30.10 Alpha Beta 2-Layer Sandwich Defensin A-like Knottin, scorpion toxin-like 1zu3A00
4HHFA 1NPIA 4V1DC 1LQHA 1WMTA 1JZAA 1L4VA 2LKBA 1MR4A 4AB0A 1GPTA 1DQ7A 1SN1A 2LI7A 2I61A 1JZBA 2A7TA 5KK4A 1PX9A 1ZYVA 1NH5A 1VNAA 2ASCA 1SN4A 5CY0A 2N66A 1ZFUA 1KV0A 1SNBA 1JKZA 1JXCA 1OZZA 1BCGA 4UJ0A 1AYJA 2KBHA 3E7RL 2KSKA 1NRAA 2BRZA 4HE7A 2YC1C 2LY6A 1BMRA 4AAZA 1I6FA 1B7DA 1AHOA 1ZVGA 1PTXA 2B3CA 2KPYA 1T0ZA 1I2UA 1NE5A 4AEIA 1SEGA 1WT7A 2LY5A 1LQIA 2KGQA 1T7BA 2B68A 1B3CA 2KBKA 2E3GA 1DJTA 2KBJA 2MZ0A 1FH3A 1BK8A 2LT8A 2N2QA 2ATBA 1P0AA 1C56A 3PSMA 2M8BB 2YBRC 4CQKA 4KYPA 1I6GA 1ZU3A 1NRBA 1N4NA 2GL1A 1I2VA 2SN3A 1T1TA 1WWNA 2E0HA 1TI5A 1VNBA 2NY8X 1CHZA 1CN2A 1PE4A 1LQQA 2LJ7A 1ZYWA 3E7UX 1ICAA 2LJMA 2KJAA 2N69A 2N2RA 2KYQA 2LR3A 1T7EA 2YEOA 2NY9X 1C55A 1MYNA 1P00A 1ZVEA 1ZUTA 1OMYA 1BRZA 1T7AA 2E3FA 1GPSA
chains in the Genus database with same CATH superfamily
4HHFA 1NPIA 5F0XA 4V1DC 2MN5A 1LQHA 3FZKA 3QFUA 4UADE 4FL9A 1QQMA 3IUCA 1HJOA 1QQNA 2QXLA 1WMTA 1NGCA 1JZAA 3BK3C 2KHOA 5EVZA 2LKBA 1MR4A 5FPEA 1L4VA 4AB0A 4UAFE 3KHWA 1GPTA 1DQ7A 1SN1A 2K35A 2LI7A 2I61A 1JZBA 2QWPA 3L4IA 2E8AA 3LDQA 1YUWA 2A7TA 1QQOA 5KK4A 3C7NB 5AQXA 1XRSB 1PX9A 1ZYVA 2YIOA 1DKGD 5AR0A 4UAEF 2QWQA 3KP0A 5AQVA 1NH5A 1VNAA 2D56A 2ASCA 5EXWA 1SN4A 2G2KA 5F1XA 5CY0A 2QWNA 2GMOA 3CW4A 3KOZA 2N66A 1ZFUA 3M3ZA 5AQLA 2VY6A 1KV0A 1SNBA 5F2RA 1JKZA 2V7ZA 5AQIA 1JXCA 1OZZA 1BCGA 1KAYA 1NGAA 3QFPA 1POIA 2KBHA 3E7RL 1NGDA 2KSKA 3LDOA 3L56A 4UJ0A 1AYJA 1BUPA 1NRAA 3KP1A 5AQHA 5BPLA 2YIPA 5EY4A 5BPNA 2BRZA 4H5RA 3D2FB 4HE7A 2YC1C 2LY6A 1BMRA 4AAZA 1I6FA 3FZFA 3FZHA 1BA1A 4H5VA 1B7DA 2QWMA 1AHOA 1ZVGA 1NGJA 1PTXA 1ATRA 2B3CA 2KPYA 1T0ZA 1I2UA 3ATUA 1NE5A 4AEIA 1GPSA 1BA0A 1SEGA 1WT7A 2LY5A 1HX1A 3ATVA 4KBOA 1LQIA 2YILA 2KGQA 1T7BA 2B68A 4GNIA 1B3CA 3KOYA 5AQNA 1HPMA 2KBKA 3AY9A 2E3GA 4H5WA 3FE1A 1DJTA 3R2VA 2KBJA 2MZ0A 3HSCA 3KC6A 1FH3A 2QWLA 5AQFA 2JDQD 1BK8A 5AQGA 2LT8A 2N2QA 2ATBA 5AQUA 5FPDA 1P0AA 1C56A 3PSMA 3A8YA 5AQKA 1UGLA 2M8BB 2YBRC 5AQYA 3LDNA 4KYPA 4CQKA 1K8BA 1I6GA 1ZU3A 2E88A 2MBKA 3D2EA 4HWIA 1NRBA 1N4NA 2GL1A 5BN9A 1I2VA 2E2FA 3KOWA 5FPNA 2SN3A 3JXUA 5AQJA 3L6QA 1T1TA 1WWNA 2E0HA 1TI5A 3C7NA 1VNBA 1NGIA 4FSVA 2NY8X 1CHZA 1CN2A 1PE4A 1LQQA 3FZLA 5AQTA 3FZMA 2LJ7A 3SF4D 4H5TA 5AQWA 3KVGA 1ZYWA 3E7UX 5AQPA 1ICAA 2LJMA 2KJAA 3I33A 2N69A 3D2EB 5BPMA 5EX5A 2N2RA 2KYQA 2LR3A 3GL1A 1T7EA 1KAZA 2YEOA 1NGGA 3CQXA 5AQZA 2QWOA 2QWRA 3LDLA 4H5NA 5AQRA 5AQSA 1NGFA 2NY9X 4IO8A 5AQMA 1C55A 1MYNA 3GKUA 5AQQA 1P00A 1NGEA 1ZVEA 1ZUTA 1OMYA 3KOXA 1KAXA 1NGBA 1S3XA 3GDQA 3LDPA 3QMLA 3D2FA 1ATSA 5BN8A 1BRZA 5AQOA 5FPMA 1NGHA 1T7AA 2LN8A 2E3FA 2QW9A 2BUPA 3QI7A
chains in the Genus database with same CATH topology
4HHFA 1NPIA 4V1DC 1LQHA 1WMTA 1JZAA 1L4VA 2LKBA 1MR4A 4AB0A 1GPTA 1DQ7A 1SN1A 2LI7A 2I61A 1JZBA 2A7TA 5KK4A 1PX9A 1ZYVA 1NH5A 1VNAA 2ASCA 1SN4A 5CY0A 2N66A 1ZFUA 1KV0A 1SNBA 1JKZA 1JXCA 1OZZA 1BCGA 4UJ0A 1AYJA 2KBHA 3E7RL 2KSKA 1NRAA 2BRZA 4HE7A 2YC1C 2LY6A 1BMRA 4AAZA 1I6FA 1B7DA 1AHOA 1ZVGA 1PTXA 2B3CA 2KPYA 1T0ZA 1I2UA 1NE5A 4AEIA 1SEGA 1WT7A 2LY5A 1LQIA 2KGQA 1T7BA 2B68A 1B3CA 2KBKA 2E3GA 1DJTA 2KBJA 2MZ0A 1FH3A 1BK8A 2LT8A 2N2QA 2ATBA 1P0AA 1C56A 3PSMA 2M8BB 2YBRC 4CQKA 4KYPA 1I6GA 1ZU3A 1NRBA 1N4NA 2GL1A 1I2VA 2SN3A 1T1TA 1WWNA 2E0HA 1TI5A 1VNBA 2NY8X 1CHZA 1CN2A 1PE4A 1LQQA 2LJ7A 1ZYWA 3E7UX 1ICAA 2LJMA 2KJAA 2N69A 2N2RA 2KYQA 2LR3A 1T7EA 2YEOA 2NY9X 1C55A 1MYNA 1P00A 1ZVEA 1ZUTA 1OMYA 1BRZA 1T7AA 2E3FA 1GPSA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4HHF A;  1NPI A;  4V1D C;  1LQH A;  1WMT A;  1JZA A;  1L4V A;  2LKB A;  1MR4 A;  4AB0 A;  1GPT A;  1DQ7 A;  1SN1 A;  2LI7 A;  2I61 A;  1JZB A;  2A7T A;  5KK4 A;  1PX9 A;  1ZYV A;  1NH5 A;  1VNA A;  2ASC A;  1SN4 A;  5CY0 A;  2N66 A;  1ZFU A;  1KV0 A;  1SNB A;  1JKZ A;  1JXC A;  1OZZ A;  1BCG A;  4UJ0 A;  1AYJ A;  2KBH A;  3E7R L;  2KSK A;  1NRA A;  2BRZ A;  4HE7 A;  2YC1 C;  2LY6 A;  1BMR A;  4AAZ A;  1I6F A;  1B7D A;  1AHO A;  1ZVG A;  1PTX A;  2B3C A;  2KPY A;  1T0Z A;  1I2U A;  1NE5 A;  4AEI A;  1SEG A;  1WT7 A;  2LY5 A;  1LQI A;  2KGQ A;  1T7B A;  2B68 A;  1B3C A;  2KBK A;  2E3G A;  1DJT A;  2KBJ A;  2MZ0 A;  1FH3 A;  1BK8 A;  2LT8 A;  2N2Q A;  2ATB A;  1P0A A;  1C56 A;  3PSM A;  2M8B B;  2YBR C;  4CQK A;  4KYP A;  1I6G A;  1ZU3 A;  1NRB A;  1N4N A;  2GL1 A;  1I2V A;  2SN3 A;  1T1T A;  1WWN A;  2E0H A;  1TI5 A;  1VNB A;  2NY8 X;  1CHZ A;  1CN2 A;  1PE4 A;  1LQQ A;  2LJ7 A;  1ZYW A;  3E7U X;  1ICA A;  2LJM A;  2KJA A;  2N69 A;  2N2R A;  2KYQ A;  2LR3 A;  1T7E A;  2YEO A;  2NY9 X;  1C55 A;  1MYN A;  1P00 A;  1ZVE A;  1ZUT A;  1OMY A;  1BRZ A;  1T7A A;  2E3F A;  1GPS A; 
#chains in the Genus database with same CATH topology
 4HHF A;  1NPI A;  5F0X A;  4V1D C;  2MN5 A;  1LQH A;  3FZK A;  3QFU A;  4UAD E;  4FL9 A;  1QQM A;  3IUC A;  1HJO A;  1QQN A;  2QXL A;  1WMT A;  1NGC A;  1JZA A;  3BK3 C;  2KHO A;  5EVZ A;  2LKB A;  1MR4 A;  5FPE A;  1L4V A;  4AB0 A;  4UAF E;  3KHW A;  1GPT A;  1DQ7 A;  1SN1 A;  2K35 A;  2LI7 A;  2I61 A;  1JZB A;  2QWP A;  3L4I A;  2E8A A;  3LDQ A;  1YUW A;  2A7T A;  1QQO A;  5KK4 A;  3C7N B;  5AQX A;  1XRS B;  1PX9 A;  1ZYV A;  2YIO A;  1DKG D;  5AR0 A;  4UAE F;  2QWQ A;  3KP0 A;  5AQV A;  1NH5 A;  1VNA A;  2D56 A;  2ASC A;  5EXW A;  1SN4 A;  2G2K A;  5F1X A;  5CY0 A;  2QWN A;  2GMO A;  3CW4 A;  3KOZ A;  2N66 A;  1ZFU A;  3M3Z A;  5AQL A;  2VY6 A;  1KV0 A;  1SNB A;  5F2R A;  1JKZ A;  2V7Z A;  5AQI A;  1JXC A;  1OZZ A;  1BCG A;  1KAY A;  1NGA A;  3QFP A;  1POI A;  2KBH A;  3E7R L;  1NGD A;  2KSK A;  3LDO A;  3L56 A;  4UJ0 A;  1AYJ A;  1BUP A;  1NRA A;  3KP1 A;  5AQH A;  5BPL A;  2YIP A;  5EY4 A;  5BPN A;  2BRZ A;  4H5R A;  3D2F B;  4HE7 A;  2YC1 C;  2LY6 A;  1BMR A;  4AAZ A;  1I6F A;  3FZF A;  3FZH A;  1BA1 A;  4H5V A;  1B7D A;  2QWM A;  1AHO A;  1ZVG A;  1NGJ A;  1PTX A;  1ATR A;  2B3C A;  2KPY A;  1T0Z A;  1I2U A;  3ATU A;  1NE5 A;  4AEI A;  1GPS A;  1BA0 A;  1SEG A;  1WT7 A;  2LY5 A;  1HX1 A;  3ATV A;  4KBO A;  1LQI A;  2YIL A;  2KGQ A;  1T7B A;  2B68 A;  4GNI A;  1B3C A;  3KOY A;  5AQN A;  1HPM A;  2KBK A;  3AY9 A;  2E3G A;  4H5W A;  3FE1 A;  1DJT A;  3R2V A;  2KBJ A;  2MZ0 A;  3HSC A;  3KC6 A;  1FH3 A;  2QWL A;  5AQF A;  2JDQ D;  1BK8 A;  5AQG A;  2LT8 A;  2N2Q A;  2ATB A;  5AQU A;  5FPD A;  1P0A A;  1C56 A;  3PSM A;  3A8Y A;  5AQK A;  1UGL A;  2M8B B;  2YBR C;  5AQY A;  3LDN A;  4KYP A;  4CQK A;  1K8B A;  1I6G A;  1ZU3 A;  2E88 A;  2MBK A;  3D2E A;  4HWI A;  1NRB A;  1N4N A;  2GL1 A;  5BN9 A;  1I2V A;  2E2F A;  3KOW A;  5FPN A;  2SN3 A;  3JXU A;  5AQJ A;  3L6Q A;  1T1T A;  1WWN A;  2E0H A;  1TI5 A;  3C7N A;  1VNB A;  1NGI A;  4FSV A;  2NY8 X;  1CHZ A;  1CN2 A;  1PE4 A;  1LQQ A;  3FZL A;  5AQT A;  3FZM A;  2LJ7 A;  3SF4 D;  4H5T A;  5AQW A;  3KVG A;  1ZYW A;  3E7U X;  5AQP A;  1ICA A;  2LJM A;  2KJA A;  3I33 A;  2N69 A;  3D2E B;  5BPM A;  5EX5 A;  2N2R A;  2KYQ A;  2LR3 A;  3GL1 A;  1T7E A;  1KAZ A;  2YEO A;  1NGG A;  3CQX A;  5AQZ A;  2QWO A;  2QWR A;  3LDL A;  4H5N A;  5AQR A;  5AQS A;  1NGF A;  2NY9 X;  4IO8 A;  5AQM A;  1C55 A;  1MYN A;  3GKU A;  5AQQ A;  1P00 A;  1NGE A;  1ZVE A;  1ZUT A;  1OMY A;  3KOX A;  1KAX A;  1NGB A;  1S3X A;  3GDQ A;  3LDP A;  3QML A;  3D2F A;  1ATS A;  5BN8 A;  1BRZ A;  5AQO A;  5FPM A;  1NGH A;  1T7A A;  2LN8 A;  2E3F A;  2QW9 A;  2BUP A;  3QI7 A; 
#chains in the Genus database with same CATH homology
 4HHF A;  1NPI A;  4V1D C;  1LQH A;  1WMT A;  1JZA A;  1L4V A;  2LKB A;  1MR4 A;  4AB0 A;  1GPT A;  1DQ7 A;  1SN1 A;  2LI7 A;  2I61 A;  1JZB A;  2A7T A;  5KK4 A;  1PX9 A;  1ZYV A;  1NH5 A;  1VNA A;  2ASC A;  1SN4 A;  5CY0 A;  2N66 A;  1ZFU A;  1KV0 A;  1SNB A;  1JKZ A;  1JXC A;  1OZZ A;  1BCG A;  4UJ0 A;  1AYJ A;  2KBH A;  3E7R L;  2KSK A;  1NRA A;  2BRZ A;  4HE7 A;  2YC1 C;  2LY6 A;  1BMR A;  4AAZ A;  1I6F A;  1B7D A;  1AHO A;  1ZVG A;  1PTX A;  2B3C A;  2KPY A;  1T0Z A;  1I2U A;  1NE5 A;  4AEI A;  1SEG A;  1WT7 A;  2LY5 A;  1LQI A;  2KGQ A;  1T7B A;  2B68 A;  1B3C A;  2KBK A;  2E3G A;  1DJT A;  2KBJ A;  2MZ0 A;  1FH3 A;  1BK8 A;  2LT8 A;  2N2Q A;  2ATB A;  1P0A A;  1C56 A;  3PSM A;  2M8B B;  2YBR C;  4CQK A;  4KYP A;  1I6G A;  1ZU3 A;  1NRB A;  1N4N A;  2GL1 A;  1I2V A;  2SN3 A;  1T1T A;  1WWN A;  2E0H A;  1TI5 A;  1VNB A;  2NY8 X;  1CHZ A;  1CN2 A;  1PE4 A;  1LQQ A;  2LJ7 A;  1ZYW A;  3E7U X;  1ICA A;  2LJM A;  2KJA A;  2N69 A;  2N2R A;  2KYQ A;  2LR3 A;  1T7E A;  2YEO A;  2NY9 X;  1C55 A;  1MYN A;  1P00 A;  1ZVE A;  1ZUT A;  1OMY A;  1BRZ A;  1T7A A;  2E3F A;  1GPS A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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