1CN2A

Solution structure of toxin 2 from centruroides noxius hoffmann, a beta scorpion neurotoxin acting on sodium channels, nmr, 15 structures
Total Genus 14
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
14
sequence length
66
structure length
66
Chain Sequence
KEGYLVDKNTGCKYECLKLGDNDYCLRECKQQYGKGAGGYCYAFACWCTHLYEQAIVWPLPNKRCS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Solution structure of toxin 2 from centruroides noxius Hoffmann, a beta-scorpion neurotoxin acting on sodium channels.
pubmed doi rcsb
molecule tags Neurotoxin
molecule keywords TOXIN 2
total genus 14
structure length 66
sequence length 66
ec nomenclature
pdb deposition date 1998-06-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00537 Toxin_3 Scorpion toxin-like domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.30.10 Alpha Beta 2-Layer Sandwich Defensin A-like Knottin, scorpion toxin-like 1cn2A00
2KJAA 2YBRC 1PE4A 2GL1A 1BCGA 4CQKA 1B7DA 2KGQA 1PX9A 2KBKA 1GPTA 1WT7A 1ZU3A 2E3FA 1OMYA 1C56A 2LJ7A 2LR3A 1AYJA 1I2VA 1ZVEA 1MYNA 4HE7A 1T0ZA 1I6FA 2NY9X 1VNBA 1SEGA 2YEOA 1BK8A 1OZZA 1ZVGA 2ATBA 1I2UA 4HHFA 1N4NA 2LY5A 1DJTA 2NY8X 1B3CA 1NE5A 1BRZA 1JKZA 2B68A 1MR4A 2M8BB 1NPIA 1DQ7A 1TI5A 1JZAA 2E3GA 1VNAA 2LJMA 1WWNA 1C55A 4AAZA 2ASCA 1BMRA 2B3CA 1P00A 2KPYA 2KBHA 1T7EA 1ZUTA 1I6GA 1JZBA 4KYPA 2E0HA 2N2RA 1KV0A 3PSMA 2LY6A 2I61A 1SN4A 2LKBA 1T1TA 2N2QA 2LT8A 2YC1C 1NRBA 1CN2A 1ZYVA 1JXCA 4AB0A 1T7AA 2A7TA 4V1DC 1NRAA 1FH3A 1P0AA 4UJ0A 1ICAA 2MZ0A 3E7RL 2N66A 1SNBA 3E7UX 1LQIA 2KSKA 2BRZA 1SN1A 4AEIA 2SN3A 1LQQA 5KK4A 2KBJA 1NH5A 1ZYWA 1LQHA 2KYQA 2LI7A 1CHZA 1GPSA 1T7BA 2N69A 1PTXA 5CY0A 1ZFUA 1WMTA 1AHOA 1L4VA
chains in the Genus database with same CATH superfamily
2KJAA 2YBRC 5AQRA 1PE4A 2GL1A 3KOZA 1BCGA 4CQKA 1NGDA 1B7DA 3D2FA 2KGQA 1PX9A 4FSVA 5F1XA 2KBKA 5AQFA 4HWIA 1WT7A 1GPTA 1ZU3A 5AQMA 2E3FA 2QXLA 5F0XA 1OMYA 1C56A 1NGCA 2LJ7A 1NGHA 2E88A 2LN8A 2LR3A 1POIA 3KOWA 1AYJA 1I2VA 4UADE 5AQZA 1ZVEA 2D56A 1MYNA 2E2FA 4HE7A 3HSCA 2QWRA 1T0ZA 5AQVA 1I6FA 2NY9X 3JXUA 5BPNA 1KAXA 1K8BA 2VY6A 1VNBA 1SEGA 2YEOA 5AQXA 5FPMA 5BN8A 1BK8A 1DKGD 1KAZA 1OZZA 1ZVGA 3ATUA 5BPLA 2ATBA 5BN9A 5AQKA 3KOXA 3FZMA 1I2UA 5AR0A 3BK3C 3ATVA 1KAYA 4H5WA 5AQJA 4HHFA 3D2FB 1NGBA 1N4NA 2LY5A 1DJTA 5AQTA 2QWLA 3KC6A 2NY8X 1B3CA 3GDQA 2GMOA 3FZFA 2YIOA 2QWOA 4H5TA 1NE5A 4H5RA 3FZHA 1ATRA 1QQMA 3SF4D 3KP1A 1BRZA 1JKZA 1YUWA 3AY9A 2B68A 1MR4A 5AQYA 2M8BB 1NPIA 5FPDA 1NGFA 1DQ7A 4IO8A 2QWPA 1TI5A 3KHWA 1ATSA 1JZAA 3R2VA 3C7NA 1NGJA 3I33A 5AQWA 1NGEA 1HX1A 5AQUA 2E3GA 1HJOA 5F2RA 1VNAA 2BUPA 2LJMA 1L4VA 3FE1A 3QFPA 1WWNA 1C55A 4AAZA 2ASCA 3CQXA 2B3CA 1P00A 3L4IA 2KPYA 2KBHA 1NGIA 1BMRA 5FPEA 1T7EA 2K35A 1ZUTA 1BA1A 2YIPA 1I6GA 1JZBA 3QFUA 2E0HA 1BUPA 2N2RA 2G2KA 3FZLA 4KYPA 3M3ZA 1KV0A 3D2EA 2LY6A 3CW4A 1UGLA 3LDQA 3PSMA 3LDOA 4FL9A 2I61A 1SN4A 2LKBA 4GNIA 3C7NB 3LDNA 3LDPA 1T1TA 3L6QA 2N2QA 5BPMA 2LT8A 2YC1C 1NRBA 1CN2A 1ZYVA 5EX5A 1JXCA 4UAFE 5AQIA 1T7AA 2A7TA 4AB0A 3KP0A 5EY4A 4V1DC 1NRAA 1QQOA 2QWQA 3QMLA 1FH3A 1P0AA 4KBOA 4UJ0A 2MZ0A 1ICAA 5AQLA 1NGGA 3E7RL 3GL1A 2N66A 1SNBA 3E7UX 1LQIA 2V7ZA 2KSKA 2BRZA 1SN1A 3A8YA 4H5VA 4UAEF 5FPNA 4AEIA 4H5NA 3D2EB 1XRSB 2QWMA 1LQQA 2SN3A 2KBJA 5AQQA 5KK4A 1NH5A 1ZYWA 2YILA 2QW9A 1LQHA 2MN5A 2KYQA 5AQSA 3LDLA 1HPMA 2LI7A 3KVGA 1CHZA 5AQGA 3QI7A 1GPSA 3L56A 2E8AA 1T7BA 2N69A 1NGAA 1PTXA 5EVZA 1ZFUA 2MBKA 1S3XA 3GKUA 5CY0A 5AQHA 1WMTA 1AHOA 2QWNA 3KOYA 3FZKA 3IUCA 5AQPA 5AQOA 2JDQD 2KHOA 5EXWA 1BA0A 5AQNA 1QQNA
chains in the Genus database with same CATH topology
2KJAA 2YBRC 1PE4A 2GL1A 1BCGA 4CQKA 1B7DA 2KGQA 1PX9A 2KBKA 1GPTA 1WT7A 1ZU3A 2E3FA 1OMYA 1C56A 2LJ7A 2LR3A 1AYJA 1I2VA 1ZVEA 1MYNA 4HE7A 1T0ZA 1I6FA 2NY9X 1VNBA 1SEGA 2YEOA 1BK8A 1OZZA 1ZVGA 2ATBA 1I2UA 4HHFA 1N4NA 2LY5A 1DJTA 2NY8X 1B3CA 1NE5A 1BRZA 1JKZA 2B68A 1MR4A 2M8BB 1NPIA 1DQ7A 1TI5A 1JZAA 2E3GA 1VNAA 2LJMA 1WWNA 1C55A 4AAZA 2ASCA 1BMRA 2B3CA 1P00A 2KPYA 2KBHA 1T7EA 1ZUTA 1I6GA 1JZBA 4KYPA 2E0HA 2N2RA 1KV0A 3PSMA 2LY6A 2I61A 1SN4A 2LKBA 1T1TA 2N2QA 2LT8A 2YC1C 1NRBA 1CN2A 1ZYVA 1JXCA 4AB0A 1T7AA 2A7TA 4V1DC 1NRAA 1FH3A 1P0AA 4UJ0A 1ICAA 2MZ0A 3E7RL 2N66A 1SNBA 3E7UX 1LQIA 2KSKA 2BRZA 1SN1A 4AEIA 2SN3A 1LQQA 5KK4A 2KBJA 1NH5A 1ZYWA 1LQHA 2KYQA 2LI7A 1CHZA 1GPSA 1T7BA 2N69A 1PTXA 5CY0A 1ZFUA 1WMTA 1AHOA 1L4VA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2KJA A;  2YBR C;  1PE4 A;  2GL1 A;  1BCG A;  4CQK A;  1B7D A;  2KGQ A;  1PX9 A;  2KBK A;  1GPT A;  1WT7 A;  1ZU3 A;  2E3F A;  1OMY A;  1C56 A;  2LJ7 A;  2LR3 A;  1AYJ A;  1I2V A;  1ZVE A;  1MYN A;  4HE7 A;  1T0Z A;  1I6F A;  2NY9 X;  1VNB A;  1SEG A;  2YEO A;  1BK8 A;  1OZZ A;  1ZVG A;  2ATB A;  1I2U A;  4HHF A;  1N4N A;  2LY5 A;  1DJT A;  2NY8 X;  1B3C A;  1NE5 A;  1BRZ A;  1JKZ A;  2B68 A;  1MR4 A;  2M8B B;  1NPI A;  1DQ7 A;  1TI5 A;  1JZA A;  2E3G A;  1VNA A;  2LJM A;  1WWN A;  1C55 A;  4AAZ A;  2ASC A;  1BMR A;  2B3C A;  1P00 A;  2KPY A;  2KBH A;  1T7E A;  1ZUT A;  1I6G A;  1JZB A;  4KYP A;  2E0H A;  2N2R A;  1KV0 A;  3PSM A;  2LY6 A;  2I61 A;  1SN4 A;  2LKB A;  1T1T A;  2N2Q A;  2LT8 A;  2YC1 C;  1NRB A;  1CN2 A;  1ZYV A;  1JXC A;  4AB0 A;  1T7A A;  2A7T A;  4V1D C;  1NRA A;  1FH3 A;  1P0A A;  4UJ0 A;  1ICA A;  2MZ0 A;  3E7R L;  2N66 A;  1SNB A;  3E7U X;  1LQI A;  2KSK A;  2BRZ A;  1SN1 A;  4AEI A;  2SN3 A;  1LQQ A;  5KK4 A;  2KBJ A;  1NH5 A;  1ZYW A;  1LQH A;  2KYQ A;  2LI7 A;  1CHZ A;  1GPS A;  1T7B A;  2N69 A;  1PTX A;  5CY0 A;  1ZFU A;  1WMT A;  1AHO A;  1L4V A; 
#chains in the Genus database with same CATH topology
 2KJA A;  2YBR C;  5AQR A;  1PE4 A;  2GL1 A;  3KOZ A;  1BCG A;  4CQK A;  1NGD A;  1B7D A;  3D2F A;  2KGQ A;  1PX9 A;  4FSV A;  5F1X A;  2KBK A;  5AQF A;  4HWI A;  1WT7 A;  1GPT A;  1ZU3 A;  5AQM A;  2E3F A;  2QXL A;  5F0X A;  1OMY A;  1C56 A;  1NGC A;  2LJ7 A;  1NGH A;  2E88 A;  2LN8 A;  2LR3 A;  1POI A;  3KOW A;  1AYJ A;  1I2V A;  4UAD E;  5AQZ A;  1ZVE A;  2D56 A;  1MYN A;  2E2F A;  4HE7 A;  3HSC A;  2QWR A;  1T0Z A;  5AQV A;  1I6F A;  2NY9 X;  3JXU A;  5BPN A;  1KAX A;  1K8B A;  2VY6 A;  1VNB A;  1SEG A;  2YEO A;  5AQX A;  5FPM A;  5BN8 A;  1BK8 A;  1DKG D;  1KAZ A;  1OZZ A;  1ZVG A;  3ATU A;  5BPL A;  2ATB A;  5BN9 A;  5AQK A;  3KOX A;  3FZM A;  1I2U A;  5AR0 A;  3BK3 C;  3ATV A;  1KAY A;  4H5W A;  5AQJ A;  4HHF A;  3D2F B;  1NGB A;  1N4N A;  2LY5 A;  1DJT A;  5AQT A;  2QWL A;  3KC6 A;  2NY8 X;  1B3C A;  3GDQ A;  2GMO A;  3FZF A;  2YIO A;  2QWO A;  4H5T A;  1NE5 A;  4H5R A;  3FZH A;  1ATR A;  1QQM A;  3SF4 D;  3KP1 A;  1BRZ A;  1JKZ A;  1YUW A;  3AY9 A;  2B68 A;  1MR4 A;  5AQY A;  2M8B B;  1NPI A;  5FPD A;  1NGF A;  1DQ7 A;  4IO8 A;  2QWP A;  1TI5 A;  3KHW A;  1ATS A;  1JZA A;  3R2V A;  3C7N A;  1NGJ A;  3I33 A;  5AQW A;  1NGE A;  1HX1 A;  5AQU A;  2E3G A;  1HJO A;  5F2R A;  1VNA A;  2BUP A;  2LJM A;  1L4V A;  3FE1 A;  3QFP A;  1WWN A;  1C55 A;  4AAZ A;  2ASC A;  3CQX A;  2B3C A;  1P00 A;  3L4I A;  2KPY A;  2KBH A;  1NGI A;  1BMR A;  5FPE A;  1T7E A;  2K35 A;  1ZUT A;  1BA1 A;  2YIP A;  1I6G A;  1JZB A;  3QFU A;  2E0H A;  1BUP A;  2N2R A;  2G2K A;  3FZL A;  4KYP A;  3M3Z A;  1KV0 A;  3D2E A;  2LY6 A;  3CW4 A;  1UGL A;  3LDQ A;  3PSM A;  3LDO A;  4FL9 A;  2I61 A;  1SN4 A;  2LKB A;  4GNI A;  3C7N B;  3LDN A;  3LDP A;  1T1T A;  3L6Q A;  2N2Q A;  5BPM A;  2LT8 A;  2YC1 C;  1NRB A;  1CN2 A;  1ZYV A;  5EX5 A;  1JXC A;  4UAF E;  5AQI A;  1T7A A;  2A7T A;  4AB0 A;  3KP0 A;  5EY4 A;  4V1D C;  1NRA A;  1QQO A;  2QWQ A;  3QML A;  1FH3 A;  1P0A A;  4KBO A;  4UJ0 A;  2MZ0 A;  1ICA A;  5AQL A;  1NGG A;  3E7R L;  3GL1 A;  2N66 A;  1SNB A;  3E7U X;  1LQI A;  2V7Z A;  2KSK A;  2BRZ A;  1SN1 A;  3A8Y A;  4H5V A;  4UAE F;  5FPN A;  4AEI A;  4H5N A;  3D2E B;  1XRS B;  2QWM A;  1LQQ A;  2SN3 A;  2KBJ A;  5AQQ A;  5KK4 A;  1NH5 A;  1ZYW A;  2YIL A;  2QW9 A;  1LQH A;  2MN5 A;  2KYQ A;  5AQS A;  3LDL A;  1HPM A;  2LI7 A;  3KVG A;  1CHZ A;  5AQG A;  3QI7 A;  1GPS A;  3L56 A;  2E8A A;  1T7B A;  2N69 A;  1NGA A;  1PTX A;  5EVZ A;  1ZFU A;  2MBK A;  1S3X A;  3GKU A;  5CY0 A;  5AQH A;  1WMT A;  1AHO A;  2QWN A;  3KOY A;  3FZK A;  3IUC A;  5AQP A;  5AQO A;  2JDQ D;  2KHO A;  5EXW A;  1BA0 A;  5AQN A;  1QQN A; 
#chains in the Genus database with same CATH homology
 2KJA A;  2YBR C;  1PE4 A;  2GL1 A;  1BCG A;  4CQK A;  1B7D A;  2KGQ A;  1PX9 A;  2KBK A;  1GPT A;  1WT7 A;  1ZU3 A;  2E3F A;  1OMY A;  1C56 A;  2LJ7 A;  2LR3 A;  1AYJ A;  1I2V A;  1ZVE A;  1MYN A;  4HE7 A;  1T0Z A;  1I6F A;  2NY9 X;  1VNB A;  1SEG A;  2YEO A;  1BK8 A;  1OZZ A;  1ZVG A;  2ATB A;  1I2U A;  4HHF A;  1N4N A;  2LY5 A;  1DJT A;  2NY8 X;  1B3C A;  1NE5 A;  1BRZ A;  1JKZ A;  2B68 A;  1MR4 A;  2M8B B;  1NPI A;  1DQ7 A;  1TI5 A;  1JZA A;  2E3G A;  1VNA A;  2LJM A;  1WWN A;  1C55 A;  4AAZ A;  2ASC A;  1BMR A;  2B3C A;  1P00 A;  2KPY A;  2KBH A;  1T7E A;  1ZUT A;  1I6G A;  1JZB A;  4KYP A;  2E0H A;  2N2R A;  1KV0 A;  3PSM A;  2LY6 A;  2I61 A;  1SN4 A;  2LKB A;  1T1T A;  2N2Q A;  2LT8 A;  2YC1 C;  1NRB A;  1CN2 A;  1ZYV A;  1JXC A;  4AB0 A;  1T7A A;  2A7T A;  4V1D C;  1NRA A;  1FH3 A;  1P0A A;  4UJ0 A;  1ICA A;  2MZ0 A;  3E7R L;  2N66 A;  1SNB A;  3E7U X;  1LQI A;  2KSK A;  2BRZ A;  1SN1 A;  4AEI A;  2SN3 A;  1LQQ A;  5KK4 A;  2KBJ A;  1NH5 A;  1ZYW A;  1LQH A;  2KYQ A;  2LI7 A;  1CHZ A;  1GPS A;  1T7B A;  2N69 A;  1PTX A;  5CY0 A;  1ZFU A;  1WMT A;  1AHO A;  1L4V A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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