1CN2A

Solution structure of toxin 2 from centruroides noxius hoffmann, a beta scorpion neurotoxin acting on sodium channels, nmr, 15 structures
Total Genus 14

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
14
sequence length
66
structure length
66
Chain Sequence
KEGYLVDKNTGCKYECLKLGDNDYCLRECKQQYGKGAGGYCYAFACWCTHLYEQAIVWPLPNKRCS

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
EMPTYTI1 (52-55)S1 (3-4)S3 (45-48)TIV1 (7-10)TIV2 (8-11)TIV6 (41-44)AH1 (23-31)S2 (39-42)TIV3 (18-21)TIV5 (34-37)TIV4 (31-34)TIV8 (61-64)TI2 (60-63)Updating...
connected with : NaN
molecule tags Neurotoxin
publication title Solution structure of toxin 2 from centruroides noxius Hoffmann, a beta-scorpion neurotoxin acting on sodium channels.
pubmed doi rcsb
molecule keywords TOXIN 2
total genus 14
structure length 66
sequence length 66
ec nomenclature
pdb deposition date 1998-06-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00537 Toxin_3 Scorpion toxin-like domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.30.10 Alpha Beta 2-Layer Sandwich Defensin A-like Knottin, scorpion toxin-like 1cn2A00
1AYJA 1TI5A 1I2VA 2A7TA 5CY0A 2N2RA 2N2QA 1CN2A 1AHOA 2B3CA 1ZU3A 2YEOA 1B3CA 2LJ7A 1CHZA 4CQKA 1I2UA 1OMYA 2N69A 4HHFA 1OZZA 1ICAA 1WMTA 1PX9A 2M8BB 1B7DA 2E3GA 2KYQA 1VNAA 1C55A 2YBRC 1T0ZA 4HE7A 1JKZA 1JZAA 2NY8X 2KPYA 1BK8A 1DQ7A 1JXCA 2KBJA 1MR4A 1SNBA 1NE5A 1MYNA 2ATBA 4KYPA 1ZYWA 1BCGA 4V1DC 2KSKA 2NY9X 2LJMA 4UJ0A 2MZ0A 1WT7A 1ZUTA 2E0HA 3PSMA 2E3FA 1NH5A 1T7AA 1WWNA 2SN3A 4AB0A 2LY5A 1BMRA 1P0AA 1ZFUA 1N4NA 1T7BA 1NRBA 2LR3A 1DJTA 1LQHA 2BRZA 1SN4A 1C56A 2KGQA 1JZBA 1ZVEA 2LKBA 1GPSA 2LI7A 1T1TA 1NRAA 3E7UX 2KJAA 2LY6A 1PE4A 1KV0A 1VNBA 1L4VA 1LQIA 4AAZA 1I6GA 2ASCA 1ZVGA 5KK4A 1BRZA 2KBHA 1I6FA 1LQQA 1T7EA 1NPIA 2GL1A 2B68A 1PTXA 1SN1A 2LT8A 1P00A 2N66A 1GPTA 1FH3A 2KBKA 2I61A 1SEGA 2YC1C 4AEIA 1ZYVA 3E7RL
chains in the Genus database with same CATH superfamily
1AYJA 1NGGA 4H5TA 1TI5A 1I2VA 1K8BA 4UAEF 2A7TA 3FZFA 2N2RA 3KC6A 5CY0A 5BN9A 2QWNA 2N2QA 5AQZA 1CN2A 1AHOA 2B3CA 3D2EB 1ZU3A 2YEOA 3QFPA 5AQOA 1NGIA 3LDOA 5AQWA 3GKUA 3KOWA 4H5VA 1B3CA 2LJ7A 5AQXA 1CHZA 4CQKA 1I2UA 1KAZA 1OMYA 2N69A 4HHFA 1OZZA 4FL9A 1ICAA 1WMTA 3C7NB 3FZKA 1PX9A 2M8BB 1HX1A 1B7DA 2GMOA 2E3GA 2QWRA 5AQFA 2D56A 3FZLA 1NGDA 2KYQA 3M3ZA 5AQYA 5F0XA 1NGEA 1VNAA 2YILA 1C55A 2YBRC 1T0ZA 5BPNA 3CW4A 4HE7A 1JKZA 3QMLA 1JZAA 1UGLA 2MN5A 3LDLA 5AQQA 2MBKA 2NY8X 2KPYA 1BK8A 3IUCA 2QXLA 3KOYA 1DQ7A 1QQOA 1JXCA 2K35A 2QWQA 2KBJA 1MR4A 3L56A 1SNBA 1NE5A 3KOXA 5AQPA 1MYNA 1ATSA 2ATBA 4KYPA 3A8YA 5AQIA 1ZYWA 1BCGA 4V1DC 2KSKA 2NY9X 3KP0A 2QWLA 2LJMA 5AQKA 5F1XA 5AR0A 2QWOA 3D2FB 4UADE 2G2KA 2KHOA 2LN8A 1BA1A 1QQMA 2E8AA 4UJ0A 2MZ0A 3HSCA 1WT7A 1ZUTA 5AQJA 2E0HA 4GNIA 5FPNA 3PSMA 2E3FA 1NH5A 1T7AA 1WWNA 3KVGA 3D2EA 5F2RA 4UAFE 3ATVA 2SN3A 1KAXA 2LY5A 3QI7A 4AB0A 1BMRA 1P0AA 1ZFUA 2V7ZA 1N4NA 1NGJA 3L6QA 5AQTA 5AQHA 1T7BA 1NRBA 2LR3A 1BA0A 3AY9A 1DJTA 1LQHA 3I33A 3KOZA 3C7NA 3R2VA 5EX5A 4H5RA 5FPDA 1HJOA 1NGCA 3L4IA 5AQGA 2BRZA 5FPEA 1SN4A 1C56A 2KGQA 2BUPA 3SF4D 2E2FA 1KAYA 4H5NA 5AQVA 3LDNA 1JZBA 3KP1A 1ZVEA 2LKBA 1GPSA 2LI7A 2VY6A 1T1TA 5EXWA 1NRAA 3E7UX 1DKGD 2KJAA 3ATUA 3GDQA 3FE1A 2LY6A 1PE4A 1KV0A 1VNBA 3QFUA 5AQSA 5EY4A 1L4VA 4FSVA 1LQIA 1QQNA 5AQNA 4AAZA 1I6GA 3FZHA 1ATRA 3JXUA 1XRSB 1S3XA 1POIA 2ASCA 2YIOA 1NGBA 5AQUA 1ZVGA 5KK4A 1BUPA 1BRZA 2KBHA 4KBOA 2YIPA 1I6FA 5EVZA 5BN8A 5BPLA 5AQLA 1T7EA 1LQQA 1NPIA 1NGAA 2GL1A 2B68A 4HWIA 1PTXA 1SN1A 2LT8A 1P00A 2E88A 3D2FA 3FZMA 3GL1A 5AQRA 2N66A 5FPMA 1NGHA 3KHWA 3LDQA 5AQMA 2QWMA 1GPTA 3CQXA 1HPMA 1FH3A 3LDPA 2KBKA 2I61A 1SEGA 1NGFA 2JDQD 4H5WA 3BK3C 4IO8A 2QW9A 2YC1C 4AEIA 1ZYVA 1YUWA 2QWPA 5BPMA 3E7RL
chains in the Genus database with same CATH topology
1AYJA 1TI5A 1I2VA 2A7TA 5CY0A 2N2RA 2N2QA 1CN2A 1AHOA 2B3CA 1ZU3A 2YEOA 1B3CA 2LJ7A 1CHZA 4CQKA 1I2UA 1OMYA 2N69A 4HHFA 1OZZA 1ICAA 1WMTA 1PX9A 2M8BB 1B7DA 2E3GA 2KYQA 1VNAA 1C55A 2YBRC 1T0ZA 4HE7A 1JKZA 1JZAA 2NY8X 2KPYA 1BK8A 1DQ7A 1JXCA 2KBJA 1MR4A 1SNBA 1NE5A 1MYNA 2ATBA 4KYPA 1ZYWA 1BCGA 4V1DC 2KSKA 2NY9X 2LJMA 4UJ0A 2MZ0A 1WT7A 1ZUTA 2E0HA 3PSMA 2E3FA 1NH5A 1T7AA 1WWNA 2SN3A 4AB0A 2LY5A 1BMRA 1P0AA 1ZFUA 1N4NA 1T7BA 1NRBA 2LR3A 1DJTA 1LQHA 2BRZA 1SN4A 1C56A 2KGQA 1JZBA 1ZVEA 2LKBA 1GPSA 2LI7A 1T1TA 1NRAA 3E7UX 2KJAA 2LY6A 1PE4A 1KV0A 1VNBA 1L4VA 1LQIA 4AAZA 1I6GA 2ASCA 1ZVGA 5KK4A 1BRZA 2KBHA 1I6FA 1LQQA 1T7EA 1NPIA 2GL1A 2B68A 1PTXA 1SN1A 2LT8A 1P00A 2N66A 1GPTA 1FH3A 2KBKA 2I61A 1SEGA 2YC1C 4AEIA 1ZYVA 3E7RL
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1AYJ A;  1TI5 A;  1I2V A;  2A7T A;  5CY0 A;  2N2R A;  2N2Q A;  1CN2 A;  1AHO A;  2B3C A;  1ZU3 A;  2YEO A;  1B3C A;  2LJ7 A;  1CHZ A;  4CQK A;  1I2U A;  1OMY A;  2N69 A;  4HHF A;  1OZZ A;  1ICA A;  1WMT A;  1PX9 A;  2M8B B;  1B7D A;  2E3G A;  2KYQ A;  1VNA A;  1C55 A;  2YBR C;  1T0Z A;  4HE7 A;  1JKZ A;  1JZA A;  2NY8 X;  2KPY A;  1BK8 A;  1DQ7 A;  1JXC A;  2KBJ A;  1MR4 A;  1SNB A;  1NE5 A;  1MYN A;  2ATB A;  4KYP A;  1ZYW A;  1BCG A;  4V1D C;  2KSK A;  2NY9 X;  2LJM A;  4UJ0 A;  2MZ0 A;  1WT7 A;  1ZUT A;  2E0H A;  3PSM A;  2E3F A;  1NH5 A;  1T7A A;  1WWN A;  2SN3 A;  4AB0 A;  2LY5 A;  1BMR A;  1P0A A;  1ZFU A;  1N4N A;  1T7B A;  1NRB A;  2LR3 A;  1DJT A;  1LQH A;  2BRZ A;  1SN4 A;  1C56 A;  2KGQ A;  1JZB A;  1ZVE A;  2LKB A;  1GPS A;  2LI7 A;  1T1T A;  1NRA A;  3E7U X;  2KJA A;  2LY6 A;  1PE4 A;  1KV0 A;  1VNB A;  1L4V A;  1LQI A;  4AAZ A;  1I6G A;  2ASC A;  1ZVG A;  5KK4 A;  1BRZ A;  2KBH A;  1I6F A;  1LQQ A;  1T7E A;  1NPI A;  2GL1 A;  2B68 A;  1PTX A;  1SN1 A;  2LT8 A;  1P00 A;  2N66 A;  1GPT A;  1FH3 A;  2KBK A;  2I61 A;  1SEG A;  2YC1 C;  4AEI A;  1ZYV A;  3E7R L; 
#chains in the Genus database with same CATH topology
 1AYJ A;  1NGG A;  4H5T A;  1TI5 A;  1I2V A;  1K8B A;  4UAE F;  2A7T A;  3FZF A;  2N2R A;  3KC6 A;  5CY0 A;  5BN9 A;  2QWN A;  2N2Q A;  5AQZ A;  1CN2 A;  1AHO A;  2B3C A;  3D2E B;  1ZU3 A;  2YEO A;  3QFP A;  5AQO A;  1NGI A;  3LDO A;  5AQW A;  3GKU A;  3KOW A;  4H5V A;  1B3C A;  2LJ7 A;  5AQX A;  1CHZ A;  4CQK A;  1I2U A;  1KAZ A;  1OMY A;  2N69 A;  4HHF A;  1OZZ A;  4FL9 A;  1ICA A;  1WMT A;  3C7N B;  3FZK A;  1PX9 A;  2M8B B;  1HX1 A;  1B7D A;  2GMO A;  2E3G A;  2QWR A;  5AQF A;  2D56 A;  3FZL A;  1NGD A;  2KYQ A;  3M3Z A;  5AQY A;  5F0X A;  1NGE A;  1VNA A;  2YIL A;  1C55 A;  2YBR C;  1T0Z A;  5BPN A;  3CW4 A;  4HE7 A;  1JKZ A;  3QML A;  1JZA A;  1UGL A;  2MN5 A;  3LDL A;  5AQQ A;  2MBK A;  2NY8 X;  2KPY A;  1BK8 A;  3IUC A;  2QXL A;  3KOY A;  1DQ7 A;  1QQO A;  1JXC A;  2K35 A;  2QWQ A;  2KBJ A;  1MR4 A;  3L56 A;  1SNB A;  1NE5 A;  3KOX A;  5AQP A;  1MYN A;  1ATS A;  2ATB A;  4KYP A;  3A8Y A;  5AQI A;  1ZYW A;  1BCG A;  4V1D C;  2KSK A;  2NY9 X;  3KP0 A;  2QWL A;  2LJM A;  5AQK A;  5F1X A;  5AR0 A;  2QWO A;  3D2F B;  4UAD E;  2G2K A;  2KHO A;  2LN8 A;  1BA1 A;  1QQM A;  2E8A A;  4UJ0 A;  2MZ0 A;  3HSC A;  1WT7 A;  1ZUT A;  5AQJ A;  2E0H A;  4GNI A;  5FPN A;  3PSM A;  2E3F A;  1NH5 A;  1T7A A;  1WWN A;  3KVG A;  3D2E A;  5F2R A;  4UAF E;  3ATV A;  2SN3 A;  1KAX A;  2LY5 A;  3QI7 A;  4AB0 A;  1BMR A;  1P0A A;  1ZFU A;  2V7Z A;  1N4N A;  1NGJ A;  3L6Q A;  5AQT A;  5AQH A;  1T7B A;  1NRB A;  2LR3 A;  1BA0 A;  3AY9 A;  1DJT A;  1LQH A;  3I33 A;  3KOZ A;  3C7N A;  3R2V A;  5EX5 A;  4H5R A;  5FPD A;  1HJO A;  1NGC A;  3L4I A;  5AQG A;  2BRZ A;  5FPE A;  1SN4 A;  1C56 A;  2KGQ A;  2BUP A;  3SF4 D;  2E2F A;  1KAY A;  4H5N A;  5AQV A;  3LDN A;  1JZB A;  3KP1 A;  1ZVE A;  2LKB A;  1GPS A;  2LI7 A;  2VY6 A;  1T1T A;  5EXW A;  1NRA A;  3E7U X;  1DKG D;  2KJA A;  3ATU A;  3GDQ A;  3FE1 A;  2LY6 A;  1PE4 A;  1KV0 A;  1VNB A;  3QFU A;  5AQS A;  5EY4 A;  1L4V A;  4FSV A;  1LQI A;  1QQN A;  5AQN A;  4AAZ A;  1I6G A;  3FZH A;  1ATR A;  3JXU A;  1XRS B;  1S3X A;  1POI A;  2ASC A;  2YIO A;  1NGB A;  5AQU A;  1ZVG A;  5KK4 A;  1BUP A;  1BRZ A;  2KBH A;  4KBO A;  2YIP A;  1I6F A;  5EVZ A;  5BN8 A;  5BPL A;  5AQL A;  1T7E A;  1LQQ A;  1NPI A;  1NGA A;  2GL1 A;  2B68 A;  4HWI A;  1PTX A;  1SN1 A;  2LT8 A;  1P00 A;  2E88 A;  3D2F A;  3FZM A;  3GL1 A;  5AQR A;  2N66 A;  5FPM A;  1NGH A;  3KHW A;  3LDQ A;  5AQM A;  2QWM A;  1GPT A;  3CQX A;  1HPM A;  1FH3 A;  3LDP A;  2KBK A;  2I61 A;  1SEG A;  1NGF A;  2JDQ D;  4H5W A;  3BK3 C;  4IO8 A;  2QW9 A;  2YC1 C;  4AEI A;  1ZYV A;  1YUW A;  2QWP A;  5BPM A;  3E7R L; 
#chains in the Genus database with same CATH homology
 1AYJ A;  1TI5 A;  1I2V A;  2A7T A;  5CY0 A;  2N2R A;  2N2Q A;  1CN2 A;  1AHO A;  2B3C A;  1ZU3 A;  2YEO A;  1B3C A;  2LJ7 A;  1CHZ A;  4CQK A;  1I2U A;  1OMY A;  2N69 A;  4HHF A;  1OZZ A;  1ICA A;  1WMT A;  1PX9 A;  2M8B B;  1B7D A;  2E3G A;  2KYQ A;  1VNA A;  1C55 A;  2YBR C;  1T0Z A;  4HE7 A;  1JKZ A;  1JZA A;  2NY8 X;  2KPY A;  1BK8 A;  1DQ7 A;  1JXC A;  2KBJ A;  1MR4 A;  1SNB A;  1NE5 A;  1MYN A;  2ATB A;  4KYP A;  1ZYW A;  1BCG A;  4V1D C;  2KSK A;  2NY9 X;  2LJM A;  4UJ0 A;  2MZ0 A;  1WT7 A;  1ZUT A;  2E0H A;  3PSM A;  2E3F A;  1NH5 A;  1T7A A;  1WWN A;  2SN3 A;  4AB0 A;  2LY5 A;  1BMR A;  1P0A A;  1ZFU A;  1N4N A;  1T7B A;  1NRB A;  2LR3 A;  1DJT A;  1LQH A;  2BRZ A;  1SN4 A;  1C56 A;  2KGQ A;  1JZB A;  1ZVE A;  2LKB A;  1GPS A;  2LI7 A;  1T1T A;  1NRA A;  3E7U X;  2KJA A;  2LY6 A;  1PE4 A;  1KV0 A;  1VNB A;  1L4V A;  1LQI A;  4AAZ A;  1I6G A;  2ASC A;  1ZVG A;  5KK4 A;  1BRZ A;  2KBH A;  1I6F A;  1LQQ A;  1T7E A;  1NPI A;  2GL1 A;  2B68 A;  1PTX A;  1SN1 A;  2LT8 A;  1P00 A;  2N66 A;  1GPT A;  1FH3 A;  2KBK A;  2I61 A;  1SEG A;  2YC1 C;  4AEI A;  1ZYV A;  3E7R L; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...