1I2VA

Nmr solution structures of an antifungal and antibacterial mutant of heliomicin
Total Genus 8
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
8
sequence length
44
structure length
44
Chain Sequence
DKLIGSCVWGAVNYTSDCNGECLLRGYKGGHCGSFANVNCWCET
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Solution structures of the antifungal heliomicin and a selected variant with both antibacterial and antifungal activities.
pubmed doi rcsb
molecule tags Antimicrobial protein
source organism Heliothis virescens
molecule keywords DEFENSIN HELIOMICIN
total genus 8
structure length 44
sequence length 44
ec nomenclature
pdb deposition date 2001-02-12
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.30.10 Alpha Beta 2-Layer Sandwich Defensin A-like Knottin, scorpion toxin-like 1i2vA00
1JZAA 1JXCA 2M8BB 2KBKA 1AYJA 1DJTA 2BRZA 1SN4A 1SEGA 2N2QA 1SN1A 2N2RA 1JZBA 4KYPA 1NH5A 1WWNA 1NRBA 1VNAA 1BCGA 1I2VA 1CN2A 1ZYVA 2LJ7A 2I61A 1NRAA 1ZVEA 3PSMA 1PTXA 1I6GA 1ZFUA 2E3GA 2E3FA 2LT8A 2LI7A 1LQHA 1T7BA 1I2UA 1CHZA 1SNBA 1WMTA 1BK8A 1C56A 4AB0A 1LQQA 1PE4A 1LQIA 1MYNA 2ASCA 4CQKA 1ZUTA 3E7UX 2LKBA 1FH3A 2LY5A 2YBRC 2KJAA 5CY0A 1TI5A 2KYQA 1T7AA 2KSKA 2N69A 4AAZA 1MR4A 1DQ7A 2N66A 2SN3A 1ICAA 1NE5A 1L4VA 4UJ0A 2YEOA 2MZ0A 1N4NA 1ZYWA 1OMYA 1WT7A 2B3CA 4V1DC 1GPTA 3E7RL 5KK4A 2NY8X 2E0HA 2A7TA 2B68A 1P00A 2YC1C 1NPIA 2LR3A 4AEIA 1T1TA 2LJMA 1OZZA 1B3CA 1B7DA 1VNBA 4HHFA 1BRZA 2KPYA 2ATBA 1T0ZA 1GPSA 2GL1A 2KGQA 2NY9X 1C55A 1PX9A 1BMRA 2KBHA 1I6FA 1KV0A 1T7EA 1AHOA 1JKZA 1P0AA 2LY6A 2KBJA 4HE7A 1ZVGA 1ZU3A
chains in the Genus database with same CATH superfamily
2YILA 1JZAA 1JXCA 2M8BB 3FZFA 1NGCA 3FZLA 2KBKA 5EVZA 1QQMA 1AYJA 3C7NA 1DJTA 1NGFA 3FZMA 1BUPA 2BRZA 1SN4A 5AQPA 3L6QA 1SEGA 5AQFA 5AQQA 1NGDA 2N2QA 3GL1A 5AQOA 1SN1A 4UADE 3QFPA 2KHOA 4H5VA 2K35A 5AQWA 4H5TA 2QXLA 2N2RA 1JZBA 1S3XA 4KYPA 1NH5A 1WWNA 5AQNA 5EY4A 3LDNA 1NRBA 1VNAA 1BCGA 2YIOA 2QWRA 3ATVA 3LDPA 1CN2A 2QWMA 1ZYVA 1I2VA 3LDLA 2LJ7A 2I61A 5AQXA 1NRAA 3CQXA 1ZVEA 5BPLA 2BUPA 3PSMA 4GNIA 1PTXA 3D2EB 3KOZA 3FZHA 5AQYA 4H5RA 1I6GA 3KOYA 1ZFUA 1KAXA 2E3GA 3LDQA 2E3FA 4IO8A 2LT8A 2LI7A 4FL9A 1LQHA 5BN9A 1T7BA 3D2EA 1QQNA 1I2UA 1CHZA 5BPNA 1NGAA 1SNBA 1WMTA 3BK3C 2VY6A 1BK8A 5F1XA 1C56A 1NGGA 2MBKA 5AQHA 1NGJA 4H5WA 5EXWA 4AB0A 1LQQA 1ATSA 1PE4A 1KAYA 1LQIA 1MYNA 3CW4A 3R2VA 5AQMA 3L4IA 1NGEA 4UAEF 4HWIA 5FPDA 2ASCA 2LN8A 3KVGA 1ZUTA 4CQKA 3E7UX 2LKBA 3ATUA 2LY5A 4KBOA 4FSVA 2YBRC 5AQKA 1FH3A 2E2FA 1KAZA 3KOWA 1NGBA 2KJAA 2QWPA 5CY0A 1TI5A 2KYQA 2MN5A 3QI7A 3D2FB 5AQTA 1T7AA 3QMLA 5F0XA 2KSKA 1HPMA 3KP1A 2N69A 5AQIA 1MR4A 4AAZA 1DQ7A 2N66A 2GMOA 2SN3A 3D2FA 1DKGD 1NE5A 1QQOA 2QWNA 3KOXA 4UJ0A 2YEOA 1ICAA 2MZ0A 1L4VA 1BA0A 5AQJA 1N4NA 1POIA 5AQRA 2YIPA 3IUCA 2E88A 5AQZA 1ZYWA 1NGHA 1OMYA 5AQSA 1WT7A 5AQLA 5AQVA 2B3CA 4V1DC 1GPTA 2E8AA 3QFUA 5AR0A 2V7ZA 1ATRA 3E7RL 3GDQA 5KK4A 1K8BA 5BPMA 5AQUA 2NY8X 2D56A 2E0HA 2A7TA 3GKUA 2B68A 5EX5A 1P00A 2YC1C 3L56A 5FPNA 1NPIA 2LR3A 4AEIA 1T1TA 3LDOA 5FPEA 1HX1A 2LJMA 4H5NA 3SF4D 1OZZA 1B3CA 2JDQD 1B7DA 1VNBA 2QW9A 3FZKA 4HHFA 4UAFE 1BRZA 1HJOA 2KPYA 2ATBA 3JXUA 1T0ZA 1UGLA 2GL1A 5FPMA 2KGQA 1GPSA 2NY9X 3KC6A 1C55A 1PX9A 1BMRA 3AY9A 2QWQA 3A8YA 1XRSB 2KBHA 3I33A 3KHWA 1I6FA 1KV0A 2QWLA 1T7EA 5BN8A 1AHOA 1JKZA 2G2KA 3KP0A 1P0AA 2LY6A 2QWOA 5AQGA 2KBJA 3HSCA 4HE7A 5F2RA 1BA1A 3FE1A 1ZVGA 1YUWA 3M3ZA 1NGIA 1ZU3A 3C7NB
chains in the Genus database with same CATH topology
1JZAA 1JXCA 2M8BB 2KBKA 1AYJA 1DJTA 2BRZA 1SN4A 1SEGA 2N2QA 1SN1A 2N2RA 1JZBA 4KYPA 1NH5A 1WWNA 1NRBA 1VNAA 1BCGA 1I2VA 1CN2A 1ZYVA 2LJ7A 2I61A 1NRAA 1ZVEA 3PSMA 1PTXA 1I6GA 1ZFUA 2E3GA 2E3FA 2LT8A 2LI7A 1LQHA 1T7BA 1I2UA 1CHZA 1SNBA 1WMTA 1BK8A 1C56A 4AB0A 1LQQA 1PE4A 1LQIA 1MYNA 2ASCA 4CQKA 1ZUTA 3E7UX 2LKBA 1FH3A 2LY5A 2YBRC 2KJAA 5CY0A 1TI5A 2KYQA 1T7AA 2KSKA 2N69A 4AAZA 1MR4A 1DQ7A 2N66A 2SN3A 1ICAA 1NE5A 1L4VA 4UJ0A 2YEOA 2MZ0A 1N4NA 1ZYWA 1OMYA 1WT7A 2B3CA 4V1DC 1GPTA 3E7RL 5KK4A 2NY8X 2E0HA 2A7TA 2B68A 1P00A 2YC1C 1NPIA 2LR3A 4AEIA 1T1TA 2LJMA 1OZZA 1B3CA 1B7DA 1VNBA 4HHFA 1BRZA 2KPYA 2ATBA 1T0ZA 1GPSA 2GL1A 2KGQA 2NY9X 1C55A 1PX9A 1BMRA 2KBHA 1I6FA 1KV0A 1T7EA 1AHOA 1JKZA 1P0AA 2LY6A 2KBJA 4HE7A 1ZVGA 1ZU3A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1JZA A;  1JXC A;  2M8B B;  2KBK A;  1AYJ A;  1DJT A;  2BRZ A;  1SN4 A;  1SEG A;  2N2Q A;  1SN1 A;  2N2R A;  1JZB A;  4KYP A;  1NH5 A;  1WWN A;  1NRB A;  1VNA A;  1BCG A;  1I2V A;  1CN2 A;  1ZYV A;  2LJ7 A;  2I61 A;  1NRA A;  1ZVE A;  3PSM A;  1PTX A;  1I6G A;  1ZFU A;  2E3G A;  2E3F A;  2LT8 A;  2LI7 A;  1LQH A;  1T7B A;  1I2U A;  1CHZ A;  1SNB A;  1WMT A;  1BK8 A;  1C56 A;  4AB0 A;  1LQQ A;  1PE4 A;  1LQI A;  1MYN A;  2ASC A;  4CQK A;  1ZUT A;  3E7U X;  2LKB A;  1FH3 A;  2LY5 A;  2YBR C;  2KJA A;  5CY0 A;  1TI5 A;  2KYQ A;  1T7A A;  2KSK A;  2N69 A;  4AAZ A;  1MR4 A;  1DQ7 A;  2N66 A;  2SN3 A;  1ICA A;  1NE5 A;  1L4V A;  4UJ0 A;  2YEO A;  2MZ0 A;  1N4N A;  1ZYW A;  1OMY A;  1WT7 A;  2B3C A;  4V1D C;  1GPT A;  3E7R L;  5KK4 A;  2NY8 X;  2E0H A;  2A7T A;  2B68 A;  1P00 A;  2YC1 C;  1NPI A;  2LR3 A;  4AEI A;  1T1T A;  2LJM A;  1OZZ A;  1B3C A;  1B7D A;  1VNB A;  4HHF A;  1BRZ A;  2KPY A;  2ATB A;  1T0Z A;  1GPS A;  2GL1 A;  2KGQ A;  2NY9 X;  1C55 A;  1PX9 A;  1BMR A;  2KBH A;  1I6F A;  1KV0 A;  1T7E A;  1AHO A;  1JKZ A;  1P0A A;  2LY6 A;  2KBJ A;  4HE7 A;  1ZVG A;  1ZU3 A; 
#chains in the Genus database with same CATH topology
 2YIL A;  1JZA A;  1JXC A;  2M8B B;  3FZF A;  1NGC A;  3FZL A;  2KBK A;  5EVZ A;  1QQM A;  1AYJ A;  3C7N A;  1DJT A;  1NGF A;  3FZM A;  1BUP A;  2BRZ A;  1SN4 A;  5AQP A;  3L6Q A;  1SEG A;  5AQF A;  5AQQ A;  1NGD A;  2N2Q A;  3GL1 A;  5AQO A;  1SN1 A;  4UAD E;  3QFP A;  2KHO A;  4H5V A;  2K35 A;  5AQW A;  4H5T A;  2QXL A;  2N2R A;  1JZB A;  1S3X A;  4KYP A;  1NH5 A;  1WWN A;  5AQN A;  5EY4 A;  3LDN A;  1NRB A;  1VNA A;  1BCG A;  2YIO A;  2QWR A;  3ATV A;  3LDP A;  1CN2 A;  2QWM A;  1ZYV A;  1I2V A;  3LDL A;  2LJ7 A;  2I61 A;  5AQX A;  1NRA A;  3CQX A;  1ZVE A;  5BPL A;  2BUP A;  3PSM A;  4GNI A;  1PTX A;  3D2E B;  3KOZ A;  3FZH A;  5AQY A;  4H5R A;  1I6G A;  3KOY A;  1ZFU A;  1KAX A;  2E3G A;  3LDQ A;  2E3F A;  4IO8 A;  2LT8 A;  2LI7 A;  4FL9 A;  1LQH A;  5BN9 A;  1T7B A;  3D2E A;  1QQN A;  1I2U A;  1CHZ A;  5BPN A;  1NGA A;  1SNB A;  1WMT A;  3BK3 C;  2VY6 A;  1BK8 A;  5F1X A;  1C56 A;  1NGG A;  2MBK A;  5AQH A;  1NGJ A;  4H5W A;  5EXW A;  4AB0 A;  1LQQ A;  1ATS A;  1PE4 A;  1KAY A;  1LQI A;  1MYN A;  3CW4 A;  3R2V A;  5AQM A;  3L4I A;  1NGE A;  4UAE F;  4HWI A;  5FPD A;  2ASC A;  2LN8 A;  3KVG A;  1ZUT A;  4CQK A;  3E7U X;  2LKB A;  3ATU A;  2LY5 A;  4KBO A;  4FSV A;  2YBR C;  5AQK A;  1FH3 A;  2E2F A;  1KAZ A;  3KOW A;  1NGB A;  2KJA A;  2QWP A;  5CY0 A;  1TI5 A;  2KYQ A;  2MN5 A;  3QI7 A;  3D2F B;  5AQT A;  1T7A A;  3QML A;  5F0X A;  2KSK A;  1HPM A;  3KP1 A;  2N69 A;  5AQI A;  1MR4 A;  4AAZ A;  1DQ7 A;  2N66 A;  2GMO A;  2SN3 A;  3D2F A;  1DKG D;  1NE5 A;  1QQO A;  2QWN A;  3KOX A;  4UJ0 A;  2YEO A;  1ICA A;  2MZ0 A;  1L4V A;  1BA0 A;  5AQJ A;  1N4N A;  1POI A;  5AQR A;  2YIP A;  3IUC A;  2E88 A;  5AQZ A;  1ZYW A;  1NGH A;  1OMY A;  5AQS A;  1WT7 A;  5AQL A;  5AQV A;  2B3C A;  4V1D C;  1GPT A;  2E8A A;  3QFU A;  5AR0 A;  2V7Z A;  1ATR A;  3E7R L;  3GDQ A;  5KK4 A;  1K8B A;  5BPM A;  5AQU A;  2NY8 X;  2D56 A;  2E0H A;  2A7T A;  3GKU A;  2B68 A;  5EX5 A;  1P00 A;  2YC1 C;  3L56 A;  5FPN A;  1NPI A;  2LR3 A;  4AEI A;  1T1T A;  3LDO A;  5FPE A;  1HX1 A;  2LJM A;  4H5N A;  3SF4 D;  1OZZ A;  1B3C A;  2JDQ D;  1B7D A;  1VNB A;  2QW9 A;  3FZK A;  4HHF A;  4UAF E;  1BRZ A;  1HJO A;  2KPY A;  2ATB A;  3JXU A;  1T0Z A;  1UGL A;  2GL1 A;  5FPM A;  2KGQ A;  1GPS A;  2NY9 X;  3KC6 A;  1C55 A;  1PX9 A;  1BMR A;  3AY9 A;  2QWQ A;  3A8Y A;  1XRS B;  2KBH A;  3I33 A;  3KHW A;  1I6F A;  1KV0 A;  2QWL A;  1T7E A;  5BN8 A;  1AHO A;  1JKZ A;  2G2K A;  3KP0 A;  1P0A A;  2LY6 A;  2QWO A;  5AQG A;  2KBJ A;  3HSC A;  4HE7 A;  5F2R A;  1BA1 A;  3FE1 A;  1ZVG A;  1YUW A;  3M3Z A;  1NGI A;  1ZU3 A;  3C7N B; 
#chains in the Genus database with same CATH homology
 1JZA A;  1JXC A;  2M8B B;  2KBK A;  1AYJ A;  1DJT A;  2BRZ A;  1SN4 A;  1SEG A;  2N2Q A;  1SN1 A;  2N2R A;  1JZB A;  4KYP A;  1NH5 A;  1WWN A;  1NRB A;  1VNA A;  1BCG A;  1I2V A;  1CN2 A;  1ZYV A;  2LJ7 A;  2I61 A;  1NRA A;  1ZVE A;  3PSM A;  1PTX A;  1I6G A;  1ZFU A;  2E3G A;  2E3F A;  2LT8 A;  2LI7 A;  1LQH A;  1T7B A;  1I2U A;  1CHZ A;  1SNB A;  1WMT A;  1BK8 A;  1C56 A;  4AB0 A;  1LQQ A;  1PE4 A;  1LQI A;  1MYN A;  2ASC A;  4CQK A;  1ZUT A;  3E7U X;  2LKB A;  1FH3 A;  2LY5 A;  2YBR C;  2KJA A;  5CY0 A;  1TI5 A;  2KYQ A;  1T7A A;  2KSK A;  2N69 A;  4AAZ A;  1MR4 A;  1DQ7 A;  2N66 A;  2SN3 A;  1ICA A;  1NE5 A;  1L4V A;  4UJ0 A;  2YEO A;  2MZ0 A;  1N4N A;  1ZYW A;  1OMY A;  1WT7 A;  2B3C A;  4V1D C;  1GPT A;  3E7R L;  5KK4 A;  2NY8 X;  2E0H A;  2A7T A;  2B68 A;  1P00 A;  2YC1 C;  1NPI A;  2LR3 A;  4AEI A;  1T1T A;  2LJM A;  1OZZ A;  1B3C A;  1B7D A;  1VNB A;  4HHF A;  1BRZ A;  2KPY A;  2ATB A;  1T0Z A;  1GPS A;  2GL1 A;  2KGQ A;  2NY9 X;  1C55 A;  1PX9 A;  1BMR A;  2KBH A;  1I6F A;  1KV0 A;  1T7E A;  1AHO A;  1JKZ A;  1P0A A;  2LY6 A;  2KBJ A;  4HE7 A;  1ZVG A;  1ZU3 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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