2B3CA

Solution structure of a beta-neurotoxin from the new world scorpion centruroides sculpturatus ewing
Total Genus 10
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
10
sequence length
64
structure length
64
Chain Sequence
KDGYLVEKTGCKKTCYKLGENDFCNRECKWKHIGGSYGYCYGFGCYCEGLPDSTQTWPLPNKTC
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Solution structure of a beta-neurotoxin from the New World scorpion Centruroides sculpturatus Ewing.
pubmed doi rcsb
molecule tags Toxin
molecule keywords PROTEIN (NEUROTOXIN CSE-I)
total genus 10
structure length 64
sequence length 64
ec nomenclature
pdb deposition date 1998-12-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00537 Toxin_3 Scorpion toxin-like domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.30.10 Alpha Beta 2-Layer Sandwich Defensin A-like Knottin, scorpion toxin-like 2b3cA00
1LQIA 4HE7A 1WWNA 2YC1C 2N69A 1P00A 2KBHA 2LI7A 1AYJA 1TI5A 1AHOA 1B3CA 2ASCA 2B68A 2LJ7A 2ATBA 1I6GA 1MYNA 2KJAA 2MZ0A 1VNAA 2NY9X 1CHZA 2N2RA 1SEGA 1ZVGA 5KK4A 4HHFA 1P0AA 2SN3A 2M8BB 4KYPA 3E7RL 4UJ0A 1C55A 1MR4A 1NPIA 1T7BA 2KSKA 1BRZA 1VNBA 2NY8X 1I2UA 2E3GA 1T7EA 1PE4A 2LT8A 2YBRC 2I61A 1JZBA 1JKZA 1NH5A 3E7UX 1T0ZA 2N66A 1DQ7A 1C56A 4AEIA 2GL1A 4CQKA 2LJMA 1T7AA 4AB0A 1ICAA 1DJTA 1N4NA 1WT7A 1SN4A 2A7TA 1ZVEA 1I6FA 1NE5A 1SNBA 1OMYA 1SN1A 1B7DA 2KGQA 2KYQA 2N2QA 1BMRA 1GPTA 1OZZA 2KBJA 1BCGA 3PSMA 1ZU3A 1PTXA 1NRBA 2LKBA 1KV0A 4V1DC 1ZYWA 2LR3A 1LQHA 1T1TA 2BRZA 1BK8A 1JZAA 2LY6A 1I2VA 5CY0A 2B3CA 1NRAA 2LY5A 2YEOA 1L4VA 1FH3A 2KPYA 1WMTA 1ZUTA 1JXCA 1GPSA 2E0HA 2E3FA 1LQQA 1PX9A 1ZFUA 1ZYVA 2KBKA 4AAZA 1CN2A
chains in the Genus database with same CATH superfamily
1LQIA 4FSVA 1WWNA 4HE7A 2YC1C 2QXLA 3ATVA 3FZMA 2YIPA 2N69A 3D2EA 1P00A 2KBHA 2LI7A 4H5TA 1AYJA 1XRSB 3BK3C 1TI5A 4IO8A 5EXWA 1KAZA 1QQOA 1AHOA 2MBKA 2QWNA 2GMOA 3AY9A 5FPDA 1B3CA 5AQXA 4KBOA 1NGEA 1NGCA 1QQMA 2E8AA 3FZHA 2ASCA 3QI7A 5BPLA 1YUWA 3FZFA 3KOZA 3C7NA 2B68A 2LJ7A 2ATBA 1I6GA 1MYNA 2KJAA 3LDLA 2MZ0A 4H5RA 1NGGA 1KAYA 3FZLA 1NGHA 1VNAA 2NY9X 1CHZA 1DKGD 2N2RA 1SEGA 2QWPA 1ZVGA 3GKUA 5KK4A 4HHFA 1P0AA 5AQHA 3L6QA 5EY4A 2SN3A 2M8BB 4KYPA 5AQTA 3E7RL 1S3XA 4GNIA 4UJ0A 1C55A 1MR4A 4UAEF 1NPIA 5FPEA 1T7BA 3LDOA 3ATUA 2KSKA 2QWQA 4UADE 1NGJA 1VNBA 2NY8X 1UGLA 5AQVA 1BRZA 1HJOA 1NGIA 1I2UA 4H5VA 2E3GA 5AQPA 1T7EA 1PE4A 3L56A 2KHOA 5AQIA 2QWMA 5AQNA 5AQRA 2LT8A 1BUPA 2YBRC 2I61A 3QFPA 1JZBA 1JKZA 5FPMA 3CQXA 1NH5A 3KOYA 3E7UX 1T0ZA 3C7NB 5AQFA 5F2RA 3JXUA 3D2FA 3KP0A 2N66A 1DQ7A 1C56A 4AEIA 3KVGA 2GL1A 5AQLA 2YIOA 4CQKA 2LJMA 3M3ZA 3KC6A 1T7AA 4AB0A 1ICAA 1DJTA 1N4NA 1QQNA 1WT7A 4H5WA 5EX5A 5AQWA 3SF4D 1ATSA 1SN4A 2A7TA 2D56A 1ZVEA 3KOXA 1I6FA 3A8YA 1NE5A 1SNBA 5AR0A 3D2EB 3QMLA 1OMYA 1SN1A 2MN5A 3FE1A 3LDPA 1K8BA 3LDQA 4HWIA 1NGBA 1B7DA 2KGQA 2KYQA 2N2QA 5BN8A 3CW4A 1BMRA 1ATRA 5AQOA 5AQUA 1BA0A 1OZZA 2KBJA 3KP1A 2LN8A 1GPTA 1HPMA 3FZKA 1BCGA 2K35A 3PSMA 2QWLA 1NGFA 4H5NA 5EVZA 5AQMA 1CN2A 1ZU3A 1PTXA 5AQKA 1NRBA 3L4IA 4UAFE 2LKBA 1KV0A 2E88A 1NGAA 4V1DC 1ZYWA 2LR3A 2YILA 1LQHA 1T1TA 2BRZA 3KHWA 1BK8A 2QWRA 2QWOA 3I33A 5F0XA 1JZAA 5BPMA 2G2KA 2LY6A 3LDNA 2VY6A 1I2VA 2QW9A 5CY0A 2B3CA 1NRAA 2LY5A 2YEOA 5AQGA 1L4VA 1HX1A 5AQYA 3HSCA 1FH3A 2KPYA 5AQQA 1WMTA 3QFUA 1ZUTA 1JXCA 2V7ZA 3KOWA 2E2FA 1GPSA 2BUPA 2E0HA 3R2VA 5FPNA 3GL1A 3IUCA 5F1XA 2E3FA 1LQQA 5AQJA 5AQZA 3GDQA 1PX9A 1ZFUA 1NGDA 1KAXA 1ZYVA 2KBKA 5BPNA 5AQSA 1BA1A 1POIA 3D2FB 4AAZA 4FL9A 5BN9A 2JDQD
chains in the Genus database with same CATH topology
1LQIA 4HE7A 1WWNA 2YC1C 2N69A 1P00A 2KBHA 2LI7A 1AYJA 1TI5A 1AHOA 1B3CA 2ASCA 2B68A 2LJ7A 2ATBA 1I6GA 1MYNA 2KJAA 2MZ0A 1VNAA 2NY9X 1CHZA 2N2RA 1SEGA 1ZVGA 5KK4A 4HHFA 1P0AA 2SN3A 2M8BB 4KYPA 3E7RL 4UJ0A 1C55A 1MR4A 1NPIA 1T7BA 2KSKA 1BRZA 1VNBA 2NY8X 1I2UA 2E3GA 1T7EA 1PE4A 2LT8A 2YBRC 2I61A 1JZBA 1JKZA 1NH5A 3E7UX 1T0ZA 2N66A 1DQ7A 1C56A 4AEIA 2GL1A 4CQKA 2LJMA 1T7AA 4AB0A 1ICAA 1DJTA 1N4NA 1WT7A 1SN4A 2A7TA 1ZVEA 1I6FA 1NE5A 1SNBA 1OMYA 1SN1A 1B7DA 2KGQA 2KYQA 2N2QA 1BMRA 1GPTA 1OZZA 2KBJA 1BCGA 3PSMA 1ZU3A 1PTXA 1NRBA 2LKBA 1KV0A 4V1DC 1ZYWA 2LR3A 1LQHA 1T1TA 2BRZA 1BK8A 1JZAA 2LY6A 1I2VA 5CY0A 2B3CA 1NRAA 2LY5A 2YEOA 1L4VA 1FH3A 2KPYA 1WMTA 1ZUTA 1JXCA 1GPSA 2E0HA 2E3FA 1LQQA 1PX9A 1ZFUA 1ZYVA 2KBKA 4AAZA 1CN2A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1LQI A;  4HE7 A;  1WWN A;  2YC1 C;  2N69 A;  1P00 A;  2KBH A;  2LI7 A;  1AYJ A;  1TI5 A;  1AHO A;  1B3C A;  2ASC A;  2B68 A;  2LJ7 A;  2ATB A;  1I6G A;  1MYN A;  2KJA A;  2MZ0 A;  1VNA A;  2NY9 X;  1CHZ A;  2N2R A;  1SEG A;  1ZVG A;  5KK4 A;  4HHF A;  1P0A A;  2SN3 A;  2M8B B;  4KYP A;  3E7R L;  4UJ0 A;  1C55 A;  1MR4 A;  1NPI A;  1T7B A;  2KSK A;  1BRZ A;  1VNB A;  2NY8 X;  1I2U A;  2E3G A;  1T7E A;  1PE4 A;  2LT8 A;  2YBR C;  2I61 A;  1JZB A;  1JKZ A;  1NH5 A;  3E7U X;  1T0Z A;  2N66 A;  1DQ7 A;  1C56 A;  4AEI A;  2GL1 A;  4CQK A;  2LJM A;  1T7A A;  4AB0 A;  1ICA A;  1DJT A;  1N4N A;  1WT7 A;  1SN4 A;  2A7T A;  1ZVE A;  1I6F A;  1NE5 A;  1SNB A;  1OMY A;  1SN1 A;  1B7D A;  2KGQ A;  2KYQ A;  2N2Q A;  1BMR A;  1GPT A;  1OZZ A;  2KBJ A;  1BCG A;  3PSM A;  1ZU3 A;  1PTX A;  1NRB A;  2LKB A;  1KV0 A;  4V1D C;  1ZYW A;  2LR3 A;  1LQH A;  1T1T A;  2BRZ A;  1BK8 A;  1JZA A;  2LY6 A;  1I2V A;  5CY0 A;  2B3C A;  1NRA A;  2LY5 A;  2YEO A;  1L4V A;  1FH3 A;  2KPY A;  1WMT A;  1ZUT A;  1JXC A;  1GPS A;  2E0H A;  2E3F A;  1LQQ A;  1PX9 A;  1ZFU A;  1ZYV A;  2KBK A;  4AAZ A;  1CN2 A; 
#chains in the Genus database with same CATH topology
 1LQI A;  4FSV A;  1WWN A;  4HE7 A;  2YC1 C;  2QXL A;  3ATV A;  3FZM A;  2YIP A;  2N69 A;  3D2E A;  1P00 A;  2KBH A;  2LI7 A;  4H5T A;  1AYJ A;  1XRS B;  3BK3 C;  1TI5 A;  4IO8 A;  5EXW A;  1KAZ A;  1QQO A;  1AHO A;  2MBK A;  2QWN A;  2GMO A;  3AY9 A;  5FPD A;  1B3C A;  5AQX A;  4KBO A;  1NGE A;  1NGC A;  1QQM A;  2E8A A;  3FZH A;  2ASC A;  3QI7 A;  5BPL A;  1YUW A;  3FZF A;  3KOZ A;  3C7N A;  2B68 A;  2LJ7 A;  2ATB A;  1I6G A;  1MYN A;  2KJA A;  3LDL A;  2MZ0 A;  4H5R A;  1NGG A;  1KAY A;  3FZL A;  1NGH A;  1VNA A;  2NY9 X;  1CHZ A;  1DKG D;  2N2R A;  1SEG A;  2QWP A;  1ZVG A;  3GKU A;  5KK4 A;  4HHF A;  1P0A A;  5AQH A;  3L6Q A;  5EY4 A;  2SN3 A;  2M8B B;  4KYP A;  5AQT A;  3E7R L;  1S3X A;  4GNI A;  4UJ0 A;  1C55 A;  1MR4 A;  4UAE F;  1NPI A;  5FPE A;  1T7B A;  3LDO A;  3ATU A;  2KSK A;  2QWQ A;  4UAD E;  1NGJ A;  1VNB A;  2NY8 X;  1UGL A;  5AQV A;  1BRZ A;  1HJO A;  1NGI A;  1I2U A;  4H5V A;  2E3G A;  5AQP A;  1T7E A;  1PE4 A;  3L56 A;  2KHO A;  5AQI A;  2QWM A;  5AQN A;  5AQR A;  2LT8 A;  1BUP A;  2YBR C;  2I61 A;  3QFP A;  1JZB A;  1JKZ A;  5FPM A;  3CQX A;  1NH5 A;  3KOY A;  3E7U X;  1T0Z A;  3C7N B;  5AQF A;  5F2R A;  3JXU A;  3D2F A;  3KP0 A;  2N66 A;  1DQ7 A;  1C56 A;  4AEI A;  3KVG A;  2GL1 A;  5AQL A;  2YIO A;  4CQK A;  2LJM A;  3M3Z A;  3KC6 A;  1T7A A;  4AB0 A;  1ICA A;  1DJT A;  1N4N A;  1QQN A;  1WT7 A;  4H5W A;  5EX5 A;  5AQW A;  3SF4 D;  1ATS A;  1SN4 A;  2A7T A;  2D56 A;  1ZVE A;  3KOX A;  1I6F A;  3A8Y A;  1NE5 A;  1SNB A;  5AR0 A;  3D2E B;  3QML A;  1OMY A;  1SN1 A;  2MN5 A;  3FE1 A;  3LDP A;  1K8B A;  3LDQ A;  4HWI A;  1NGB A;  1B7D A;  2KGQ A;  2KYQ A;  2N2Q A;  5BN8 A;  3CW4 A;  1BMR A;  1ATR A;  5AQO A;  5AQU A;  1BA0 A;  1OZZ A;  2KBJ A;  3KP1 A;  2LN8 A;  1GPT A;  1HPM A;  3FZK A;  1BCG A;  2K35 A;  3PSM A;  2QWL A;  1NGF A;  4H5N A;  5EVZ A;  5AQM A;  1CN2 A;  1ZU3 A;  1PTX A;  5AQK A;  1NRB A;  3L4I A;  4UAF E;  2LKB A;  1KV0 A;  2E88 A;  1NGA A;  4V1D C;  1ZYW A;  2LR3 A;  2YIL A;  1LQH A;  1T1T A;  2BRZ A;  3KHW A;  1BK8 A;  2QWR A;  2QWO A;  3I33 A;  5F0X A;  1JZA A;  5BPM A;  2G2K A;  2LY6 A;  3LDN A;  2VY6 A;  1I2V A;  2QW9 A;  5CY0 A;  2B3C A;  1NRA A;  2LY5 A;  2YEO A;  5AQG A;  1L4V A;  1HX1 A;  5AQY A;  3HSC A;  1FH3 A;  2KPY A;  5AQQ A;  1WMT A;  3QFU A;  1ZUT A;  1JXC A;  2V7Z A;  3KOW A;  2E2F A;  1GPS A;  2BUP A;  2E0H A;  3R2V A;  5FPN A;  3GL1 A;  3IUC A;  5F1X A;  2E3F A;  1LQQ A;  5AQJ A;  5AQZ A;  3GDQ A;  1PX9 A;  1ZFU A;  1NGD A;  1KAX A;  1ZYV A;  2KBK A;  5BPN A;  5AQS A;  1BA1 A;  1POI A;  3D2F B;  4AAZ A;  4FL9 A;  5BN9 A;  2JDQ D; 
#chains in the Genus database with same CATH homology
 1LQI A;  4HE7 A;  1WWN A;  2YC1 C;  2N69 A;  1P00 A;  2KBH A;  2LI7 A;  1AYJ A;  1TI5 A;  1AHO A;  1B3C A;  2ASC A;  2B68 A;  2LJ7 A;  2ATB A;  1I6G A;  1MYN A;  2KJA A;  2MZ0 A;  1VNA A;  2NY9 X;  1CHZ A;  2N2R A;  1SEG A;  1ZVG A;  5KK4 A;  4HHF A;  1P0A A;  2SN3 A;  2M8B B;  4KYP A;  3E7R L;  4UJ0 A;  1C55 A;  1MR4 A;  1NPI A;  1T7B A;  2KSK A;  1BRZ A;  1VNB A;  2NY8 X;  1I2U A;  2E3G A;  1T7E A;  1PE4 A;  2LT8 A;  2YBR C;  2I61 A;  1JZB A;  1JKZ A;  1NH5 A;  3E7U X;  1T0Z A;  2N66 A;  1DQ7 A;  1C56 A;  4AEI A;  2GL1 A;  4CQK A;  2LJM A;  1T7A A;  4AB0 A;  1ICA A;  1DJT A;  1N4N A;  1WT7 A;  1SN4 A;  2A7T A;  1ZVE A;  1I6F A;  1NE5 A;  1SNB A;  1OMY A;  1SN1 A;  1B7D A;  2KGQ A;  2KYQ A;  2N2Q A;  1BMR A;  1GPT A;  1OZZ A;  2KBJ A;  1BCG A;  3PSM A;  1ZU3 A;  1PTX A;  1NRB A;  2LKB A;  1KV0 A;  4V1D C;  1ZYW A;  2LR3 A;  1LQH A;  1T1T A;  2BRZ A;  1BK8 A;  1JZA A;  2LY6 A;  1I2V A;  5CY0 A;  2B3C A;  1NRA A;  2LY5 A;  2YEO A;  1L4V A;  1FH3 A;  2KPY A;  1WMT A;  1ZUT A;  1JXC A;  1GPS A;  2E0H A;  2E3F A;  1LQQ A;  1PX9 A;  1ZFU A;  1ZYV A;  2KBK A;  4AAZ A;  1CN2 A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...