2E3FA

Nmr structure of def-bat, a mutant of anopheles defensin def-aaa
Total Genus 7
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
7
sequence length
43
structure length
43
Chain Sequence
ATCDLASFSSQWVTPNDSLCAAHCIARRYRGGYCNGKRVCVCR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Antimicrobial protein
source organism Anopheles gambiae
publication title Rational design of peptides active against the gram positive bacteria Staphylococcus aureus
pubmed doi rcsb
molecule keywords defensin, mutant DEF-BAT
total genus 7
structure length 43
sequence length 43
ec nomenclature
pdb deposition date 2006-11-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01097 Defensin_2 Arthropod defensin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.30.10 Alpha Beta 2-Layer Sandwich Defensin A-like Knottin, scorpion toxin-like 2e3fA00
4HE7A 1VNAA 2I61A 1B3CA 1KV0A 1AHOA 1TI5A 3E7UX 1LQQA 2MZ0A 2LT8A 2ASCA 1SEGA 1T7BA 1N4NA 4AB0A 2KPYA 2E3FA 2YBRC 4AEIA 4AAZA 1NE5A 2LY6A 1FH3A 1T0ZA 2KJAA 1BMRA 1BK8A 1OMYA 2KSKA 1ZU3A 5CY0A 1ZUTA 1WMTA 1P0AA 4HHFA 4UJ0A 2E3GA 1PTXA 1C56A 1BRZA 2N66A 2NY9X 1I6FA 1NH5A 2N69A 1ZFUA 1NRAA 2LY5A 1MYNA 1I2VA 1AYJA 1ZYVA 3E7RL 1JKZA 1T7AA 2GL1A 1SN1A 1I2UA 5KK4A 1CN2A 1P00A 1GPSA 1DJTA 1MR4A 2E0HA 1JXCA 1LQHA 2N2QA 1ICAA 4KYPA 2B3CA 2SN3A 1PE4A 4CQKA 2B68A 1LQIA 1JZBA 1SNBA 2LJ7A 3PSMA 2M8BB 1BCGA 1PX9A 2KGQA 2LR3A 1WWNA 2N2RA 2A7TA 2KBKA 1CHZA 1ZVEA 1B7DA 1NRBA 2KBHA 2LJMA 2YC1C 1ZYWA 1OZZA 2LKBA 1T7EA 1VNBA 1JZAA 1WT7A 1T1TA 1C55A 1GPTA 1ZVGA 1NPIA 2YEOA 2KYQA 1L4VA 2BRZA 2KBJA 2NY8X 4V1DC 1DQ7A 1SN4A 2LI7A 1I6GA 2ATBA
chains in the Genus database with same CATH superfamily
4HE7A 5FPDA 1VNAA 2I61A 1B3CA 1KV0A 1AHOA 3BK3C 1HX1A 1TI5A 3FZLA 3FZMA 3E7UX 1LQQA 2MZ0A 2LT8A 2ASCA 3ATUA 1SEGA 2QWLA 1KAYA 1T7BA 3KC6A 1NGBA 2QWNA 1N4NA 4AB0A 2MBKA 2KPYA 2E3FA 3FZKA 3C7NA 2YBRC 4AEIA 5AQTA 2QWOA 4AAZA 2D56A 1HJOA 1NGDA 1NE5A 2LY6A 1FH3A 5AQZA 3KOYA 5EX5A 5F2RA 3D2EB 4IO8A 2VY6A 1POIA 1T0ZA 2E2FA 2KJAA 5AQXA 2GMOA 5AQKA 5AQGA 5AQIA 5AQVA 1BMRA 1BK8A 5EVZA 1OMYA 3LDNA 2KSKA 1ZU3A 5CY0A 3SF4D 1ZUTA 1WMTA 2QWRA 2KHOA 3LDPA 1P0AA 4H5VA 4HHFA 4UADE 5AQJA 2E88A 4UJ0A 1I2VA 5F1XA 2G2KA 3KP0A 3JXUA 1KAXA 5F0XA 5FPEA 2E3GA 5AQLA 1PTXA 1C56A 3A8YA 4GNIA 5EXWA 2N66A 3KOXA 4UAEF 2NY9X 3GL1A 1BRZA 1I6FA 1NH5A 5BPNA 3IUCA 2N69A 4H5RA 1ZFUA 1KAZA 2YIPA 1NRAA 3L4IA 5AQQA 2LY5A 2QWMA 1MYNA 3FZFA 1NGEA 1NGFA 2QWPA 3FZHA 3KVGA 5AQMA 5AQSA 1NGJA 3LDOA 5EY4A 1NGAA 2LN8A 1ZYVA 4H5NA 1AYJA 3E7RL 1JKZA 1T7AA 2GL1A 1SN1A 3LDLA 1I2UA 3I33A 5KK4A 1CN2A 1P00A 1GPSA 1DJTA 2K35A 1MR4A 1NGIA 2E0HA 1JXCA 1LQHA 2QW9A 3D2EA 3KP1A 3L6QA 1K8BA 2N2QA 1HPMA 1ICAA 4KYPA 5FPMA 3D2FB 1DKGD 1NGHA 2B3CA 2SN3A 3CW4A 3GKUA 3M3ZA 4H5WA 4KBOA 1PE4A 4UAFE 5AQFA 5AQNA 4CQKA 2B68A 1LQIA 2E8AA 1JZBA 1SNBA 2LJ7A 4FSVA 3R2VA 1QQMA 3PSMA 1QQNA 2M8BB 1BCGA 3L56A 1PX9A 3QFPA 3KHWA 3KOZA 2KGQA 2V7ZA 2LR3A 3CQXA 1BA0A 1WWNA 2YIOA 1QQOA 2N2RA 2BUPA 1NGGA 2A7TA 1XRSB 1CHZA 2KBKA 4H5TA 5AQRA 5BN9A 3QMLA 1ZVEA 1B7DA 1NRBA 2KBHA 4HWIA 2LJMA 2YC1C 1NGCA 5AQWA 1ZYWA 5AQHA 1OZZA 1S3XA 2YILA 2LKBA 3HSCA 3C7NB 3GDQA 4FL9A 1T7EA 1VNBA 1JZAA 1WT7A 3FE1A 1T1TA 3LDQA 5BPLA 1UGLA 3ATVA 1C55A 1BA1A 5AQYA 1GPTA 3AY9A 1ZVGA 5AQOA 5BN8A 1NPIA 1ATRA 5AQUA 2YEOA 2QXLA 3KOWA 3D2FA 2KYQA 5BPMA 1L4VA 1BUPA 2BRZA 2JDQD 2KBJA 5FPNA 2QWQA 2NY8X 4V1DC 5AR0A 1DQ7A 1SN4A 2LI7A 1I6GA 1YUWA 3QFUA 1ATSA 2MN5A 5AQPA 3QI7A 2ATBA
chains in the Genus database with same CATH topology
4HE7A 1VNAA 2I61A 1B3CA 1KV0A 1AHOA 1TI5A 3E7UX 1LQQA 2MZ0A 2LT8A 2ASCA 1SEGA 1T7BA 1N4NA 4AB0A 2KPYA 2E3FA 2YBRC 4AEIA 4AAZA 1NE5A 2LY6A 1FH3A 1T0ZA 2KJAA 1BMRA 1BK8A 1OMYA 2KSKA 1ZU3A 5CY0A 1ZUTA 1WMTA 1P0AA 4HHFA 4UJ0A 2E3GA 1PTXA 1C56A 1BRZA 2N66A 2NY9X 1I6FA 1NH5A 2N69A 1ZFUA 1NRAA 2LY5A 1MYNA 1I2VA 1AYJA 1ZYVA 3E7RL 1JKZA 1T7AA 2GL1A 1SN1A 1I2UA 5KK4A 1CN2A 1P00A 1GPSA 1DJTA 1MR4A 2E0HA 1JXCA 1LQHA 2N2QA 1ICAA 4KYPA 2B3CA 2SN3A 1PE4A 4CQKA 2B68A 1LQIA 1JZBA 1SNBA 2LJ7A 3PSMA 2M8BB 1BCGA 1PX9A 2KGQA 2LR3A 1WWNA 2N2RA 2A7TA 2KBKA 1CHZA 1ZVEA 1B7DA 1NRBA 2KBHA 2LJMA 2YC1C 1ZYWA 1OZZA 2LKBA 1T7EA 1VNBA 1JZAA 1WT7A 1T1TA 1C55A 1GPTA 1ZVGA 1NPIA 2YEOA 2KYQA 1L4VA 2BRZA 2KBJA 2NY8X 4V1DC 1DQ7A 1SN4A 2LI7A 1I6GA 2ATBA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4HE7 A;  1VNA A;  2I61 A;  1B3C A;  1KV0 A;  1AHO A;  1TI5 A;  3E7U X;  1LQQ A;  2MZ0 A;  2LT8 A;  2ASC A;  1SEG A;  1T7B A;  1N4N A;  4AB0 A;  2KPY A;  2E3F A;  2YBR C;  4AEI A;  4AAZ A;  1NE5 A;  2LY6 A;  1FH3 A;  1T0Z A;  2KJA A;  1BMR A;  1BK8 A;  1OMY A;  2KSK A;  1ZU3 A;  5CY0 A;  1ZUT A;  1WMT A;  1P0A A;  4HHF A;  4UJ0 A;  2E3G A;  1PTX A;  1C56 A;  1BRZ A;  2N66 A;  2NY9 X;  1I6F A;  1NH5 A;  2N69 A;  1ZFU A;  1NRA A;  2LY5 A;  1MYN A;  1I2V A;  1AYJ A;  1ZYV A;  3E7R L;  1JKZ A;  1T7A A;  2GL1 A;  1SN1 A;  1I2U A;  5KK4 A;  1CN2 A;  1P00 A;  1GPS A;  1DJT A;  1MR4 A;  2E0H A;  1JXC A;  1LQH A;  2N2Q A;  1ICA A;  4KYP A;  2B3C A;  2SN3 A;  1PE4 A;  4CQK A;  2B68 A;  1LQI A;  1JZB A;  1SNB A;  2LJ7 A;  3PSM A;  2M8B B;  1BCG A;  1PX9 A;  2KGQ A;  2LR3 A;  1WWN A;  2N2R A;  2A7T A;  2KBK A;  1CHZ A;  1ZVE A;  1B7D A;  1NRB A;  2KBH A;  2LJM A;  2YC1 C;  1ZYW A;  1OZZ A;  2LKB A;  1T7E A;  1VNB A;  1JZA A;  1WT7 A;  1T1T A;  1C55 A;  1GPT A;  1ZVG A;  1NPI A;  2YEO A;  2KYQ A;  1L4V A;  2BRZ A;  2KBJ A;  2NY8 X;  4V1D C;  1DQ7 A;  1SN4 A;  2LI7 A;  1I6G A;  2ATB A; 
#chains in the Genus database with same CATH topology
 4HE7 A;  5FPD A;  1VNA A;  2I61 A;  1B3C A;  1KV0 A;  1AHO A;  3BK3 C;  1HX1 A;  1TI5 A;  3FZL A;  3FZM A;  3E7U X;  1LQQ A;  2MZ0 A;  2LT8 A;  2ASC A;  3ATU A;  1SEG A;  2QWL A;  1KAY A;  1T7B A;  3KC6 A;  1NGB A;  2QWN A;  1N4N A;  4AB0 A;  2MBK A;  2KPY A;  2E3F A;  3FZK A;  3C7N A;  2YBR C;  4AEI A;  5AQT A;  2QWO A;  4AAZ A;  2D56 A;  1HJO A;  1NGD A;  1NE5 A;  2LY6 A;  1FH3 A;  5AQZ A;  3KOY A;  5EX5 A;  5F2R A;  3D2E B;  4IO8 A;  2VY6 A;  1POI A;  1T0Z A;  2E2F A;  2KJA A;  5AQX A;  2GMO A;  5AQK A;  5AQG A;  5AQI A;  5AQV A;  1BMR A;  1BK8 A;  5EVZ A;  1OMY A;  3LDN A;  2KSK A;  1ZU3 A;  5CY0 A;  3SF4 D;  1ZUT A;  1WMT A;  2QWR A;  2KHO A;  3LDP A;  1P0A A;  4H5V A;  4HHF A;  4UAD E;  5AQJ A;  2E88 A;  4UJ0 A;  1I2V A;  5F1X A;  2G2K A;  3KP0 A;  3JXU A;  1KAX A;  5F0X A;  5FPE A;  2E3G A;  5AQL A;  1PTX A;  1C56 A;  3A8Y A;  4GNI A;  5EXW A;  2N66 A;  3KOX A;  4UAE F;  2NY9 X;  3GL1 A;  1BRZ A;  1I6F A;  1NH5 A;  5BPN A;  3IUC A;  2N69 A;  4H5R A;  1ZFU A;  1KAZ A;  2YIP A;  1NRA A;  3L4I A;  5AQQ A;  2LY5 A;  2QWM A;  1MYN A;  3FZF A;  1NGE A;  1NGF A;  2QWP A;  3FZH A;  3KVG A;  5AQM A;  5AQS A;  1NGJ A;  3LDO A;  5EY4 A;  1NGA A;  2LN8 A;  1ZYV A;  4H5N A;  1AYJ A;  3E7R L;  1JKZ A;  1T7A A;  2GL1 A;  1SN1 A;  3LDL A;  1I2U A;  3I33 A;  5KK4 A;  1CN2 A;  1P00 A;  1GPS A;  1DJT A;  2K35 A;  1MR4 A;  1NGI A;  2E0H A;  1JXC A;  1LQH A;  2QW9 A;  3D2E A;  3KP1 A;  3L6Q A;  1K8B A;  2N2Q A;  1HPM A;  1ICA A;  4KYP A;  5FPM A;  3D2F B;  1DKG D;  1NGH A;  2B3C A;  2SN3 A;  3CW4 A;  3GKU A;  3M3Z A;  4H5W A;  4KBO A;  1PE4 A;  4UAF E;  5AQF A;  5AQN A;  4CQK A;  2B68 A;  1LQI A;  2E8A A;  1JZB A;  1SNB A;  2LJ7 A;  4FSV A;  3R2V A;  1QQM A;  3PSM A;  1QQN A;  2M8B B;  1BCG A;  3L56 A;  1PX9 A;  3QFP A;  3KHW A;  3KOZ A;  2KGQ A;  2V7Z A;  2LR3 A;  3CQX A;  1BA0 A;  1WWN A;  2YIO A;  1QQO A;  2N2R A;  2BUP A;  1NGG A;  2A7T A;  1XRS B;  1CHZ A;  2KBK A;  4H5T A;  5AQR A;  5BN9 A;  3QML A;  1ZVE A;  1B7D A;  1NRB A;  2KBH A;  4HWI A;  2LJM A;  2YC1 C;  1NGC A;  5AQW A;  1ZYW A;  5AQH A;  1OZZ A;  1S3X A;  2YIL A;  2LKB A;  3HSC A;  3C7N B;  3GDQ A;  4FL9 A;  1T7E A;  1VNB A;  1JZA A;  1WT7 A;  3FE1 A;  1T1T A;  3LDQ A;  5BPL A;  1UGL A;  3ATV A;  1C55 A;  1BA1 A;  5AQY A;  1GPT A;  3AY9 A;  1ZVG A;  5AQO A;  5BN8 A;  1NPI A;  1ATR A;  5AQU A;  2YEO A;  2QXL A;  3KOW A;  3D2F A;  2KYQ A;  5BPM A;  1L4V A;  1BUP A;  2BRZ A;  2JDQ D;  2KBJ A;  5FPN A;  2QWQ A;  2NY8 X;  4V1D C;  5AR0 A;  1DQ7 A;  1SN4 A;  2LI7 A;  1I6G A;  1YUW A;  3QFU A;  1ATS A;  2MN5 A;  5AQP A;  3QI7 A;  2ATB A; 
#chains in the Genus database with same CATH homology
 4HE7 A;  1VNA A;  2I61 A;  1B3C A;  1KV0 A;  1AHO A;  1TI5 A;  3E7U X;  1LQQ A;  2MZ0 A;  2LT8 A;  2ASC A;  1SEG A;  1T7B A;  1N4N A;  4AB0 A;  2KPY A;  2E3F A;  2YBR C;  4AEI A;  4AAZ A;  1NE5 A;  2LY6 A;  1FH3 A;  1T0Z A;  2KJA A;  1BMR A;  1BK8 A;  1OMY A;  2KSK A;  1ZU3 A;  5CY0 A;  1ZUT A;  1WMT A;  1P0A A;  4HHF A;  4UJ0 A;  2E3G A;  1PTX A;  1C56 A;  1BRZ A;  2N66 A;  2NY9 X;  1I6F A;  1NH5 A;  2N69 A;  1ZFU A;  1NRA A;  2LY5 A;  1MYN A;  1I2V A;  1AYJ A;  1ZYV A;  3E7R L;  1JKZ A;  1T7A A;  2GL1 A;  1SN1 A;  1I2U A;  5KK4 A;  1CN2 A;  1P00 A;  1GPS A;  1DJT A;  1MR4 A;  2E0H A;  1JXC A;  1LQH A;  2N2Q A;  1ICA A;  4KYP A;  2B3C A;  2SN3 A;  1PE4 A;  4CQK A;  2B68 A;  1LQI A;  1JZB A;  1SNB A;  2LJ7 A;  3PSM A;  2M8B B;  1BCG A;  1PX9 A;  2KGQ A;  2LR3 A;  1WWN A;  2N2R A;  2A7T A;  2KBK A;  1CHZ A;  1ZVE A;  1B7D A;  1NRB A;  2KBH A;  2LJM A;  2YC1 C;  1ZYW A;  1OZZ A;  2LKB A;  1T7E A;  1VNB A;  1JZA A;  1WT7 A;  1T1T A;  1C55 A;  1GPT A;  1ZVG A;  1NPI A;  2YEO A;  2KYQ A;  1L4V A;  2BRZ A;  2KBJ A;  2NY8 X;  4V1D C;  1DQ7 A;  1SN4 A;  2LI7 A;  1I6G A;  2ATB A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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