2E3FA

Nmr structure of def-bat, a mutant of anopheles defensin def-aaa
Total Genus 7
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
7
sequence length
43
structure length
43
Chain Sequence
ATCDLASFSSQWVTPNDSLCAAHCIARRYRGGYCNGKRVCVCR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Rational design of peptides active against the gram positive bacteria Staphylococcus aureus
pubmed doi rcsb
molecule tags Antimicrobial protein
source organism Anopheles gambiae
molecule keywords defensin, mutant DEF-BAT
total genus 7
structure length 43
sequence length 43
ec nomenclature
pdb deposition date 2006-11-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01097 Defensin_2 Arthropod defensin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.30.10 Alpha Beta 2-Layer Sandwich Defensin A-like Knottin, scorpion toxin-like 2e3fA00
4AB0A 2LY5A 2ASCA 2YC1C 2N69A 2SN3A 4AAZA 2LT8A 2MZ0A 1PE4A 1FH3A 2LY6A 2E3FA 1DQ7A 1VNBA 4CQKA 2YBRC 4HHFA 2LI7A 1SEGA 1I2VA 4UJ0A 1I6FA 2KYQA 1NH5A 5CY0A 1LQIA 2NY9X 2LJMA 2GL1A 1AHOA 2A7TA 1TI5A 1T1TA 2I61A 1SNBA 1GPSA 1OZZA 1JKZA 1BRZA 1BMRA 2BRZA 1ZUTA 1T0ZA 2KGQA 2KBKA 1BCGA 1AYJA 2E3GA 1ZVGA 1NPIA 2N2QA 4KYPA 2B68A 2KJAA 1PTXA 1B3CA 1T7BA 1ZU3A 1ZFUA 1GPTA 2N66A 1B7DA 1CHZA 1BK8A 1VNAA 3PSMA 2KSKA 1I6GA 2LJ7A 1KV0A 1PX9A 1SN1A 1SN4A 1T7EA 2LKBA 1LQHA 1WWNA 2NY8X 2KPYA 2YEOA 1NRBA 3E7UX 1ICAA 1N4NA 1P00A 1LQQA 1I2UA 4HE7A 1P0AA 1T7AA 2KBJA 1NE5A 1MYNA 1WMTA 4AEIA 1WT7A 1DJTA 1ZVEA 3E7RL 2E0HA 1ZYWA 2LR3A 2ATBA 1ZYVA 1JXCA 1L4VA 1MR4A 1C56A 1OMYA 2M8BB 2N2RA 5KK4A 1NRAA 4V1DC 1JZBA 2KBHA 1JZAA 1CN2A 2B3CA 1C55A
chains in the Genus database with same CATH superfamily
4AB0A 2QXLA 1KAXA 3ATVA 5F2RA 2LY5A 3C7NA 2ASCA 2YC1C 2N69A 2SN3A 3CQXA 2LT8A 4AAZA 2MZ0A 1PE4A 3GKUA 5AQPA 3I33A 1FH3A 2LY6A 2E3FA 3FE1A 3KOZA 1DQ7A 1UGLA 1VNBA 2VY6A 2YIOA 5AQMA 1NGAA 4CQKA 5AQYA 2YBRC 1ATSA 4HHFA 2LI7A 5AQIA 1SEGA 1I2VA 5AR0A 4UJ0A 1I6FA 2KYQA 1ATRA 1NH5A 2QW9A 1HJOA 4GNIA 3KHWA 4UAEF 5CY0A 2G2KA 1BA0A 3D2FB 3BK3C 1LQIA 2NY9X 2LJMA 5AQRA 3A8YA 1KAZA 5F0XA 2GL1A 1AHOA 4H5TA 5AQTA 3D2EB 3L6QA 5AQKA 1DKGD 2QWRA 5BN9A 2A7TA 3KOXA 1TI5A 5AQSA 1NGCA 1BA1A 1QQOA 3JXUA 1K8BA 1T1TA 2E2FA 2I61A 2MBKA 3FZMA 5EX5A 3KOWA 3SF4D 1SNBA 1GPSA 1OZZA 2E8AA 1JKZA 5AQJA 2QWMA 5FPMA 1BRZA 2D56A 5AQHA 1BMRA 2GMOA 3CW4A 2BRZA 1BUPA 2LN8A 1ZUTA 1T0ZA 2KGQA 2YILA 2KBKA 1BCGA 1POIA 1AYJA 2QWPA 5AQWA 2E3GA 2BUPA 5AQNA 1ZVGA 3QMLA 3GL1A 1NPIA 2E88A 4UAFE 5AQOA 2N2QA 4KYPA 5FPEA 1ICAA 1NGGA 1HPMA 2B68A 2QWOA 2KJAA 1PTXA 3QFUA 1B3CA 2QWQA 3AY9A 1NGJA 1T7BA 3FZFA 3LDPA 1XRSB 1ZU3A 3IUCA 4HWIA 1ZFUA 3R2VA 3LDNA 2N66A 1B7DA 1GPTA 5AQQA 5AQXA 1CHZA 2QWLA 5EVZA 5EXWA 5FPNA 1BK8A 1NGFA 3L4IA 5AQVA 2QWNA 1VNAA 3PSMA 2KSKA 1I6GA 3ATUA 1S3XA 5AQLA 2LJ7A 1KV0A 1PX9A 1SN1A 1SN4A 1T7EA 2LKBA 3LDOA 1LQHA 3QFPA 4H5VA 1WWNA 5BPMA 3QI7A 2NY8X 2KPYA 2YEOA 3FZHA 2MN5A 5AQFA 3KVGA 5AQGA 1NRBA 3E7UX 3FZLA 2JDQD 1N4NA 1NGDA 2YIPA 1P00A 3GDQA 1LQQA 2KHOA 3LDLA 4HE7A 4IO8A 5BN8A 1I2UA 3C7NB 3KC6A 1P0AA 1T7AA 2V7ZA 2KBJA 3D2FA 5BPLA 1NE5A 1MYNA 1NGHA 1WMTA 4AEIA 1WT7A 1NGEA 1DJTA 4H5NA 1NGIA 1ZVEA 2K35A 3E7RL 3FZKA 4UADE 3M3ZA 4FSVA 5FPDA 3D2EA 5AQZA 2E0HA 1ZYWA 3KP0A 3LDQA 5F1XA 4KBOA 2LR3A 2ATBA 1ZYVA 3KOYA 1JXCA 1KAYA 3KP1A 4FL9A 1L4VA 1MR4A 1C56A 1OMYA 2M8BB 2N2RA 5KK4A 1QQNA 1YUWA 5EY4A 5AQUA 1NRAA 4V1DC 1JZBA 2KBHA 1QQMA 1JZAA 1NGBA 1CN2A 2B3CA 3L56A 5BPNA 3HSCA 4H5WA 1HX1A 4H5RA 1C55A
chains in the Genus database with same CATH topology
4AB0A 2LY5A 2ASCA 2YC1C 2N69A 2SN3A 4AAZA 2LT8A 2MZ0A 1PE4A 1FH3A 2LY6A 2E3FA 1DQ7A 1VNBA 4CQKA 2YBRC 4HHFA 2LI7A 1SEGA 1I2VA 4UJ0A 1I6FA 2KYQA 1NH5A 5CY0A 1LQIA 2NY9X 2LJMA 2GL1A 1AHOA 2A7TA 1TI5A 1T1TA 2I61A 1SNBA 1GPSA 1OZZA 1JKZA 1BRZA 1BMRA 2BRZA 1ZUTA 1T0ZA 2KGQA 2KBKA 1BCGA 1AYJA 2E3GA 1ZVGA 1NPIA 2N2QA 4KYPA 2B68A 2KJAA 1PTXA 1B3CA 1T7BA 1ZU3A 1ZFUA 1GPTA 2N66A 1B7DA 1CHZA 1BK8A 1VNAA 3PSMA 2KSKA 1I6GA 2LJ7A 1KV0A 1PX9A 1SN1A 1SN4A 1T7EA 2LKBA 1LQHA 1WWNA 2NY8X 2KPYA 2YEOA 1NRBA 3E7UX 1ICAA 1N4NA 1P00A 1LQQA 1I2UA 4HE7A 1P0AA 1T7AA 2KBJA 1NE5A 1MYNA 1WMTA 4AEIA 1WT7A 1DJTA 1ZVEA 3E7RL 2E0HA 1ZYWA 2LR3A 2ATBA 1ZYVA 1JXCA 1L4VA 1MR4A 1C56A 1OMYA 2M8BB 2N2RA 5KK4A 1NRAA 4V1DC 1JZBA 2KBHA 1JZAA 1CN2A 2B3CA 1C55A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4AB0 A;  2LY5 A;  2ASC A;  2YC1 C;  2N69 A;  2SN3 A;  4AAZ A;  2LT8 A;  2MZ0 A;  1PE4 A;  1FH3 A;  2LY6 A;  2E3F A;  1DQ7 A;  1VNB A;  4CQK A;  2YBR C;  4HHF A;  2LI7 A;  1SEG A;  1I2V A;  4UJ0 A;  1I6F A;  2KYQ A;  1NH5 A;  5CY0 A;  1LQI A;  2NY9 X;  2LJM A;  2GL1 A;  1AHO A;  2A7T A;  1TI5 A;  1T1T A;  2I61 A;  1SNB A;  1GPS A;  1OZZ A;  1JKZ A;  1BRZ A;  1BMR A;  2BRZ A;  1ZUT A;  1T0Z A;  2KGQ A;  2KBK A;  1BCG A;  1AYJ A;  2E3G A;  1ZVG A;  1NPI A;  2N2Q A;  4KYP A;  2B68 A;  2KJA A;  1PTX A;  1B3C A;  1T7B A;  1ZU3 A;  1ZFU A;  1GPT A;  2N66 A;  1B7D A;  1CHZ A;  1BK8 A;  1VNA A;  3PSM A;  2KSK A;  1I6G A;  2LJ7 A;  1KV0 A;  1PX9 A;  1SN1 A;  1SN4 A;  1T7E A;  2LKB A;  1LQH A;  1WWN A;  2NY8 X;  2KPY A;  2YEO A;  1NRB A;  3E7U X;  1ICA A;  1N4N A;  1P00 A;  1LQQ A;  1I2U A;  4HE7 A;  1P0A A;  1T7A A;  2KBJ A;  1NE5 A;  1MYN A;  1WMT A;  4AEI A;  1WT7 A;  1DJT A;  1ZVE A;  3E7R L;  2E0H A;  1ZYW A;  2LR3 A;  2ATB A;  1ZYV A;  1JXC A;  1L4V A;  1MR4 A;  1C56 A;  1OMY A;  2M8B B;  2N2R A;  5KK4 A;  1NRA A;  4V1D C;  1JZB A;  2KBH A;  1JZA A;  1CN2 A;  2B3C A;  1C55 A; 
#chains in the Genus database with same CATH topology
 4AB0 A;  2QXL A;  1KAX A;  3ATV A;  5F2R A;  2LY5 A;  3C7N A;  2ASC A;  2YC1 C;  2N69 A;  2SN3 A;  3CQX A;  2LT8 A;  4AAZ A;  2MZ0 A;  1PE4 A;  3GKU A;  5AQP A;  3I33 A;  1FH3 A;  2LY6 A;  2E3F A;  3FE1 A;  3KOZ A;  1DQ7 A;  1UGL A;  1VNB A;  2VY6 A;  2YIO A;  5AQM A;  1NGA A;  4CQK A;  5AQY A;  2YBR C;  1ATS A;  4HHF A;  2LI7 A;  5AQI A;  1SEG A;  1I2V A;  5AR0 A;  4UJ0 A;  1I6F A;  2KYQ A;  1ATR A;  1NH5 A;  2QW9 A;  1HJO A;  4GNI A;  3KHW A;  4UAE F;  5CY0 A;  2G2K A;  1BA0 A;  3D2F B;  3BK3 C;  1LQI A;  2NY9 X;  2LJM A;  5AQR A;  3A8Y A;  1KAZ A;  5F0X A;  2GL1 A;  1AHO A;  4H5T A;  5AQT A;  3D2E B;  3L6Q A;  5AQK A;  1DKG D;  2QWR A;  5BN9 A;  2A7T A;  3KOX A;  1TI5 A;  5AQS A;  1NGC A;  1BA1 A;  1QQO A;  3JXU A;  1K8B A;  1T1T A;  2E2F A;  2I61 A;  2MBK A;  3FZM A;  5EX5 A;  3KOW A;  3SF4 D;  1SNB A;  1GPS A;  1OZZ A;  2E8A A;  1JKZ A;  5AQJ A;  2QWM A;  5FPM A;  1BRZ A;  2D56 A;  5AQH A;  1BMR A;  2GMO A;  3CW4 A;  2BRZ A;  1BUP A;  2LN8 A;  1ZUT A;  1T0Z A;  2KGQ A;  2YIL A;  2KBK A;  1BCG A;  1POI A;  1AYJ A;  2QWP A;  5AQW A;  2E3G A;  2BUP A;  5AQN A;  1ZVG A;  3QML A;  3GL1 A;  1NPI A;  2E88 A;  4UAF E;  5AQO A;  2N2Q A;  4KYP A;  5FPE A;  1ICA A;  1NGG A;  1HPM A;  2B68 A;  2QWO A;  2KJA A;  1PTX A;  3QFU A;  1B3C A;  2QWQ A;  3AY9 A;  1NGJ A;  1T7B A;  3FZF A;  3LDP A;  1XRS B;  1ZU3 A;  3IUC A;  4HWI A;  1ZFU A;  3R2V A;  3LDN A;  2N66 A;  1B7D A;  1GPT A;  5AQQ A;  5AQX A;  1CHZ A;  2QWL A;  5EVZ A;  5EXW A;  5FPN A;  1BK8 A;  1NGF A;  3L4I A;  5AQV A;  2QWN A;  1VNA A;  3PSM A;  2KSK A;  1I6G A;  3ATU A;  1S3X A;  5AQL A;  2LJ7 A;  1KV0 A;  1PX9 A;  1SN1 A;  1SN4 A;  1T7E A;  2LKB A;  3LDO A;  1LQH A;  3QFP A;  4H5V A;  1WWN A;  5BPM A;  3QI7 A;  2NY8 X;  2KPY A;  2YEO A;  3FZH A;  2MN5 A;  5AQF A;  3KVG A;  5AQG A;  1NRB A;  3E7U X;  3FZL A;  2JDQ D;  1N4N A;  1NGD A;  2YIP A;  1P00 A;  3GDQ A;  1LQQ A;  2KHO A;  3LDL A;  4HE7 A;  4IO8 A;  5BN8 A;  1I2U A;  3C7N B;  3KC6 A;  1P0A A;  1T7A A;  2V7Z A;  2KBJ A;  3D2F A;  5BPL A;  1NE5 A;  1MYN A;  1NGH A;  1WMT A;  4AEI A;  1WT7 A;  1NGE A;  1DJT A;  4H5N A;  1NGI A;  1ZVE A;  2K35 A;  3E7R L;  3FZK A;  4UAD E;  3M3Z A;  4FSV A;  5FPD A;  3D2E A;  5AQZ A;  2E0H A;  1ZYW A;  3KP0 A;  3LDQ A;  5F1X A;  4KBO A;  2LR3 A;  2ATB A;  1ZYV A;  3KOY A;  1JXC A;  1KAY A;  3KP1 A;  4FL9 A;  1L4V A;  1MR4 A;  1C56 A;  1OMY A;  2M8B B;  2N2R A;  5KK4 A;  1QQN A;  1YUW A;  5EY4 A;  5AQU A;  1NRA A;  4V1D C;  1JZB A;  2KBH A;  1QQM A;  1JZA A;  1NGB A;  1CN2 A;  2B3C A;  3L56 A;  5BPN A;  3HSC A;  4H5W A;  1HX1 A;  4H5R A;  1C55 A; 
#chains in the Genus database with same CATH homology
 4AB0 A;  2LY5 A;  2ASC A;  2YC1 C;  2N69 A;  2SN3 A;  4AAZ A;  2LT8 A;  2MZ0 A;  1PE4 A;  1FH3 A;  2LY6 A;  2E3F A;  1DQ7 A;  1VNB A;  4CQK A;  2YBR C;  4HHF A;  2LI7 A;  1SEG A;  1I2V A;  4UJ0 A;  1I6F A;  2KYQ A;  1NH5 A;  5CY0 A;  1LQI A;  2NY9 X;  2LJM A;  2GL1 A;  1AHO A;  2A7T A;  1TI5 A;  1T1T A;  2I61 A;  1SNB A;  1GPS A;  1OZZ A;  1JKZ A;  1BRZ A;  1BMR A;  2BRZ A;  1ZUT A;  1T0Z A;  2KGQ A;  2KBK A;  1BCG A;  1AYJ A;  2E3G A;  1ZVG A;  1NPI A;  2N2Q A;  4KYP A;  2B68 A;  2KJA A;  1PTX A;  1B3C A;  1T7B A;  1ZU3 A;  1ZFU A;  1GPT A;  2N66 A;  1B7D A;  1CHZ A;  1BK8 A;  1VNA A;  3PSM A;  2KSK A;  1I6G A;  2LJ7 A;  1KV0 A;  1PX9 A;  1SN1 A;  1SN4 A;  1T7E A;  2LKB A;  1LQH A;  1WWN A;  2NY8 X;  2KPY A;  2YEO A;  1NRB A;  3E7U X;  1ICA A;  1N4N A;  1P00 A;  1LQQ A;  1I2U A;  4HE7 A;  1P0A A;  1T7A A;  2KBJ A;  1NE5 A;  1MYN A;  1WMT A;  4AEI A;  1WT7 A;  1DJT A;  1ZVE A;  3E7R L;  2E0H A;  1ZYW A;  2LR3 A;  2ATB A;  1ZYV A;  1JXC A;  1L4V A;  1MR4 A;  1C56 A;  1OMY A;  2M8B B;  2N2R A;  5KK4 A;  1NRA A;  4V1D C;  1JZB A;  2KBH A;  1JZA A;  1CN2 A;  2B3C A;  1C55 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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