2E3GA

Nmr structure of def-daa, a mutant of anopheles defensin def-aaa
Total Genus 4
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
4
sequence length
40
structure length
40
Chain Sequence
ATCDLASKWNWNHTLCAAHCIARRYRGGYCNSKAVCVCRN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Rational design of peptides active against the gram positive bacteria Staphylococcus aureus
pubmed doi rcsb
molecule tags Antimicrobial protein
source organism Anopheles gambiae
molecule keywords defensin, mutant DEF-DAA
total genus 4
structure length 40
sequence length 40
ec nomenclature
pdb deposition date 2006-11-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01097 Defensin_2 Arthropod defensin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.30.10 Alpha Beta 2-Layer Sandwich Defensin A-like Knottin, scorpion toxin-like 2e3gA00
2KBKA 1DJTA 1PX9A 1TI5A 1MYNA 1C56A 1NPIA 1SN4A 2E3FA 1I2UA 1P0AA 1ZVGA 1ZUTA 2LY6A 5KK4A 1AYJA 1NRBA 2KPYA 1PTXA 2B3CA 2M8BB 1JZAA 1LQIA 1T7EA 1WT7A 2KJAA 4AEIA 1I6GA 1L4VA 2KSKA 1ZYWA 1GPTA 1C55A 1OZZA 1BK8A 2YBRC 2LJ7A 1JZBA 1AHOA 2KBHA 1LQHA 2KGQA 1I2VA 1KV0A 1P00A 1T7BA 1WMTA 4HHFA 2LY5A 3E7RL 2GL1A 2LT8A 2BRZA 1NH5A 2B68A 1VNBA 1PE4A 1T0ZA 2YC1C 2N66A 4UJ0A 2LI7A 1B3CA 1OMYA 2YEOA 1MR4A 2A7TA 1BMRA 1I6FA 1DQ7A 4HE7A 2E3GA 2ASCA 1GPSA 1CHZA 1ZYVA 1BRZA 2N2RA 1SEGA 3PSMA 2KYQA 1B7DA 1ZFUA 1SNBA 4AB0A 2SN3A 4CQKA 1FH3A 1ICAA 4KYPA 2NY8X 1LQQA 1JXCA 5CY0A 2N69A 2KBJA 2NY9X 1WWNA 2I61A 2LR3A 3E7UX 1N4NA 2MZ0A 1JKZA 4V1DC 2N2QA 1BCGA 1NRAA 1NE5A 1CN2A 1ZVEA 2LKBA 1T7AA 2ATBA 2LJMA 1T1TA 1ZU3A 1VNAA 4AAZA 2E0HA 1SN1A
chains in the Genus database with same CATH superfamily
2KBKA 3JXUA 1HJOA 1DJTA 3ATVA 3BK3C 1PX9A 5EY4A 1TI5A 1C56A 1MYNA 5BPNA 1NPIA 2VY6A 5AQNA 1SN4A 2E3FA 1I2UA 1P0AA 1ZVGA 4H5VA 5AQOA 5AQMA 1ZUTA 2LY6A 5KK4A 3KOZA 4UAFE 5AQIA 1NRBA 1AYJA 2KPYA 5F0XA 2V7ZA 1PTXA 2B3CA 2M8BB 2QWOA 1JZAA 4IO8A 1QQOA 1YUWA 2KHOA 2QWPA 1LQIA 2GMOA 3L56A 4H5RA 3QMLA 4UAEF 5BPLA 3M3ZA 3QFPA 1T7EA 1WT7A 2KJAA 3FZKA 4AEIA 1I6GA 4KBOA 1L4VA 2KSKA 1ZYWA 1NGFA 5BN9A 1GPTA 3ATUA 1C55A 5AQVA 1BA0A 1OZZA 1NGBA 3GL1A 1BK8A 3R2VA 2YBRC 5AQXA 2LJ7A 2BUPA 1JZBA 1AHOA 2KBHA 5AQYA 1LQHA 2KGQA 3KVGA 3QFUA 4H5NA 3A8YA 1I2VA 1KV0A 3FZMA 3CQXA 3KHWA 2K35A 4HWIA 1P00A 5AR0A 1K8BA 1T7BA 1WMTA 4HHFA 3GDQA 2QW9A 2LY5A 3LDLA 3E7RL 5AQHA 1BA1A 1QQMA 2BRZA 1NH5A 2GL1A 2LT8A 1DKGD 5FPNA 2D56A 2E2FA 2B68A 3CW4A 1HPMA 3IUCA 1VNBA 4UADE 2E88A 1PE4A 1T0ZA 2YC1C 1QQNA 5AQZA 3SF4D 2N66A 2JDQD 4UJ0A 2LI7A 5FPDA 1B3CA 1OMYA 2YEOA 3KOYA 3FZFA 4FL9A 2QWMA 3GKUA 5AQSA 5BPMA 5FPEA 1MR4A 2A7TA 2QWNA 5F2RA 1BMRA 1I6FA 1DQ7A 3HSCA 1BUPA 4HE7A 2E3GA 1XRSB 2ASCA 3KP0A 1GPSA 1CHZA 1KAZA 1ZYVA 5AQRA 5EVZA 5AQFA 1BRZA 2MBKA 1UGLA 2N2RA 1S3XA 1SEGA 3PSMA 2KYQA 3FZHA 3I33A 2QWRA 3AY9A 1B7DA 3L6QA 1ZFUA 1NGGA 2E8AA 1KAXA 1POIA 3LDPA 1SNBA 4H5TA 4AB0A 3KOWA 3KP1A 2YIOA 3FE1A 2SN3A 4CQKA 5AQUA 1FH3A 1ICAA 5AQGA 4KYPA 2NY8X 1HX1A 2G2KA 4H5WA 5FPMA 1LQQA 1JXCA 5CY0A 2N69A 1NGHA 1ATRA 2KBJA 3KC6A 3LDOA 2NY9X 1WWNA 1NGJA 2I61A 2LR3A 3E7UX 5AQPA 5AQKA 3C7NB 2YIPA 1N4NA 3C7NA 2MZ0A 4FSVA 5BN8A 1JKZA 4V1DC 5EXWA 1NGDA 3KOXA 5EX5A 5AQJA 2QXLA 3QI7A 2N2QA 1BCGA 1NRAA 5AQWA 1KAYA 1NGIA 2LN8A 2YILA 1NE5A 3D2FB 3LDQA 3L4IA 3D2FA 1CN2A 1NGCA 4GNIA 1ATSA 2QWLA 5AQTA 1ZVEA 2LKBA 1T7AA 1NGAA 2ATBA 2LJMA 1T1TA 1NGEA 2QWQA 5AQLA 1ZU3A 1VNAA 5F1XA 3LDNA 5AQQA 4AAZA 2E0HA 2MN5A 3FZLA 3D2EB 1SN1A 3D2EA
chains in the Genus database with same CATH topology
2KBKA 1DJTA 1PX9A 1TI5A 1MYNA 1C56A 1NPIA 1SN4A 2E3FA 1I2UA 1P0AA 1ZVGA 1ZUTA 2LY6A 5KK4A 1AYJA 1NRBA 2KPYA 1PTXA 2B3CA 2M8BB 1JZAA 1LQIA 1T7EA 1WT7A 2KJAA 4AEIA 1I6GA 1L4VA 2KSKA 1ZYWA 1GPTA 1C55A 1OZZA 1BK8A 2YBRC 2LJ7A 1JZBA 1AHOA 2KBHA 1LQHA 2KGQA 1I2VA 1KV0A 1P00A 1T7BA 1WMTA 4HHFA 2LY5A 3E7RL 2GL1A 2LT8A 2BRZA 1NH5A 2B68A 1VNBA 1PE4A 1T0ZA 2YC1C 2N66A 4UJ0A 2LI7A 1B3CA 1OMYA 2YEOA 1MR4A 2A7TA 1BMRA 1I6FA 1DQ7A 4HE7A 2E3GA 2ASCA 1GPSA 1CHZA 1ZYVA 1BRZA 2N2RA 1SEGA 3PSMA 2KYQA 1B7DA 1ZFUA 1SNBA 4AB0A 2SN3A 4CQKA 1FH3A 1ICAA 4KYPA 2NY8X 1LQQA 1JXCA 5CY0A 2N69A 2KBJA 2NY9X 1WWNA 2I61A 2LR3A 3E7UX 1N4NA 2MZ0A 1JKZA 4V1DC 2N2QA 1BCGA 1NRAA 1NE5A 1CN2A 1ZVEA 2LKBA 1T7AA 2ATBA 2LJMA 1T1TA 1ZU3A 1VNAA 4AAZA 2E0HA 1SN1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2KBK A;  1DJT A;  1PX9 A;  1TI5 A;  1MYN A;  1C56 A;  1NPI A;  1SN4 A;  2E3F A;  1I2U A;  1P0A A;  1ZVG A;  1ZUT A;  2LY6 A;  5KK4 A;  1AYJ A;  1NRB A;  2KPY A;  1PTX A;  2B3C A;  2M8B B;  1JZA A;  1LQI A;  1T7E A;  1WT7 A;  2KJA A;  4AEI A;  1I6G A;  1L4V A;  2KSK A;  1ZYW A;  1GPT A;  1C55 A;  1OZZ A;  1BK8 A;  2YBR C;  2LJ7 A;  1JZB A;  1AHO A;  2KBH A;  1LQH A;  2KGQ A;  1I2V A;  1KV0 A;  1P00 A;  1T7B A;  1WMT A;  4HHF A;  2LY5 A;  3E7R L;  2GL1 A;  2LT8 A;  2BRZ A;  1NH5 A;  2B68 A;  1VNB A;  1PE4 A;  1T0Z A;  2YC1 C;  2N66 A;  4UJ0 A;  2LI7 A;  1B3C A;  1OMY A;  2YEO A;  1MR4 A;  2A7T A;  1BMR A;  1I6F A;  1DQ7 A;  4HE7 A;  2E3G A;  2ASC A;  1GPS A;  1CHZ A;  1ZYV A;  1BRZ A;  2N2R A;  1SEG A;  3PSM A;  2KYQ A;  1B7D A;  1ZFU A;  1SNB A;  4AB0 A;  2SN3 A;  4CQK A;  1FH3 A;  1ICA A;  4KYP A;  2NY8 X;  1LQQ A;  1JXC A;  5CY0 A;  2N69 A;  2KBJ A;  2NY9 X;  1WWN A;  2I61 A;  2LR3 A;  3E7U X;  1N4N A;  2MZ0 A;  1JKZ A;  4V1D C;  2N2Q A;  1BCG A;  1NRA A;  1NE5 A;  1CN2 A;  1ZVE A;  2LKB A;  1T7A A;  2ATB A;  2LJM A;  1T1T A;  1ZU3 A;  1VNA A;  4AAZ A;  2E0H A;  1SN1 A; 
#chains in the Genus database with same CATH topology
 2KBK A;  3JXU A;  1HJO A;  1DJT A;  3ATV A;  3BK3 C;  1PX9 A;  5EY4 A;  1TI5 A;  1C56 A;  1MYN A;  5BPN A;  1NPI A;  2VY6 A;  5AQN A;  1SN4 A;  2E3F A;  1I2U A;  1P0A A;  1ZVG A;  4H5V A;  5AQO A;  5AQM A;  1ZUT A;  2LY6 A;  5KK4 A;  3KOZ A;  4UAF E;  5AQI A;  1NRB A;  1AYJ A;  2KPY A;  5F0X A;  2V7Z A;  1PTX A;  2B3C A;  2M8B B;  2QWO A;  1JZA A;  4IO8 A;  1QQO A;  1YUW A;  2KHO A;  2QWP A;  1LQI A;  2GMO A;  3L56 A;  4H5R A;  3QML A;  4UAE F;  5BPL A;  3M3Z A;  3QFP A;  1T7E A;  1WT7 A;  2KJA A;  3FZK A;  4AEI A;  1I6G A;  4KBO A;  1L4V A;  2KSK A;  1ZYW A;  1NGF A;  5BN9 A;  1GPT A;  3ATU A;  1C55 A;  5AQV A;  1BA0 A;  1OZZ A;  1NGB A;  3GL1 A;  1BK8 A;  3R2V A;  2YBR C;  5AQX A;  2LJ7 A;  2BUP A;  1JZB A;  1AHO A;  2KBH A;  5AQY A;  1LQH A;  2KGQ A;  3KVG A;  3QFU A;  4H5N A;  3A8Y A;  1I2V A;  1KV0 A;  3FZM A;  3CQX A;  3KHW A;  2K35 A;  4HWI A;  1P00 A;  5AR0 A;  1K8B A;  1T7B A;  1WMT A;  4HHF A;  3GDQ A;  2QW9 A;  2LY5 A;  3LDL A;  3E7R L;  5AQH A;  1BA1 A;  1QQM A;  2BRZ A;  1NH5 A;  2GL1 A;  2LT8 A;  1DKG D;  5FPN A;  2D56 A;  2E2F A;  2B68 A;  3CW4 A;  1HPM A;  3IUC A;  1VNB A;  4UAD E;  2E88 A;  1PE4 A;  1T0Z A;  2YC1 C;  1QQN A;  5AQZ A;  3SF4 D;  2N66 A;  2JDQ D;  4UJ0 A;  2LI7 A;  5FPD A;  1B3C A;  1OMY A;  2YEO A;  3KOY A;  3FZF A;  4FL9 A;  2QWM A;  3GKU A;  5AQS A;  5BPM A;  5FPE A;  1MR4 A;  2A7T A;  2QWN A;  5F2R A;  1BMR A;  1I6F A;  1DQ7 A;  3HSC A;  1BUP A;  4HE7 A;  2E3G A;  1XRS B;  2ASC A;  3KP0 A;  1GPS A;  1CHZ A;  1KAZ A;  1ZYV A;  5AQR A;  5EVZ A;  5AQF A;  1BRZ A;  2MBK A;  1UGL A;  2N2R A;  1S3X A;  1SEG A;  3PSM A;  2KYQ A;  3FZH A;  3I33 A;  2QWR A;  3AY9 A;  1B7D A;  3L6Q A;  1ZFU A;  1NGG A;  2E8A A;  1KAX A;  1POI A;  3LDP A;  1SNB A;  4H5T A;  4AB0 A;  3KOW A;  3KP1 A;  2YIO A;  3FE1 A;  2SN3 A;  4CQK A;  5AQU A;  1FH3 A;  1ICA A;  5AQG A;  4KYP A;  2NY8 X;  1HX1 A;  2G2K A;  4H5W A;  5FPM A;  1LQQ A;  1JXC A;  5CY0 A;  2N69 A;  1NGH A;  1ATR A;  2KBJ A;  3KC6 A;  3LDO A;  2NY9 X;  1WWN A;  1NGJ A;  2I61 A;  2LR3 A;  3E7U X;  5AQP A;  5AQK A;  3C7N B;  2YIP A;  1N4N A;  3C7N A;  2MZ0 A;  4FSV A;  5BN8 A;  1JKZ A;  4V1D C;  5EXW A;  1NGD A;  3KOX A;  5EX5 A;  5AQJ A;  2QXL A;  3QI7 A;  2N2Q A;  1BCG A;  1NRA A;  5AQW A;  1KAY A;  1NGI A;  2LN8 A;  2YIL A;  1NE5 A;  3D2F B;  3LDQ A;  3L4I A;  3D2F A;  1CN2 A;  1NGC A;  4GNI A;  1ATS A;  2QWL A;  5AQT A;  1ZVE A;  2LKB A;  1T7A A;  1NGA A;  2ATB A;  2LJM A;  1T1T A;  1NGE A;  2QWQ A;  5AQL A;  1ZU3 A;  1VNA A;  5F1X A;  3LDN A;  5AQQ A;  4AAZ A;  2E0H A;  2MN5 A;  3FZL A;  3D2E B;  1SN1 A;  3D2E A; 
#chains in the Genus database with same CATH homology
 2KBK A;  1DJT A;  1PX9 A;  1TI5 A;  1MYN A;  1C56 A;  1NPI A;  1SN4 A;  2E3F A;  1I2U A;  1P0A A;  1ZVG A;  1ZUT A;  2LY6 A;  5KK4 A;  1AYJ A;  1NRB A;  2KPY A;  1PTX A;  2B3C A;  2M8B B;  1JZA A;  1LQI A;  1T7E A;  1WT7 A;  2KJA A;  4AEI A;  1I6G A;  1L4V A;  2KSK A;  1ZYW A;  1GPT A;  1C55 A;  1OZZ A;  1BK8 A;  2YBR C;  2LJ7 A;  1JZB A;  1AHO A;  2KBH A;  1LQH A;  2KGQ A;  1I2V A;  1KV0 A;  1P00 A;  1T7B A;  1WMT A;  4HHF A;  2LY5 A;  3E7R L;  2GL1 A;  2LT8 A;  2BRZ A;  1NH5 A;  2B68 A;  1VNB A;  1PE4 A;  1T0Z A;  2YC1 C;  2N66 A;  4UJ0 A;  2LI7 A;  1B3C A;  1OMY A;  2YEO A;  1MR4 A;  2A7T A;  1BMR A;  1I6F A;  1DQ7 A;  4HE7 A;  2E3G A;  2ASC A;  1GPS A;  1CHZ A;  1ZYV A;  1BRZ A;  2N2R A;  1SEG A;  3PSM A;  2KYQ A;  1B7D A;  1ZFU A;  1SNB A;  4AB0 A;  2SN3 A;  4CQK A;  1FH3 A;  1ICA A;  4KYP A;  2NY8 X;  1LQQ A;  1JXC A;  5CY0 A;  2N69 A;  2KBJ A;  2NY9 X;  1WWN A;  2I61 A;  2LR3 A;  3E7U X;  1N4N A;  2MZ0 A;  1JKZ A;  4V1D C;  2N2Q A;  1BCG A;  1NRA A;  1NE5 A;  1CN2 A;  1ZVE A;  2LKB A;  1T7A A;  2ATB A;  2LJM A;  1T1T A;  1ZU3 A;  1VNA A;  4AAZ A;  2E0H A;  1SN1 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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