2LI7A

Solution structure of cssii
Total Genus 11
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
11
sequence length
66
structure length
66
Chain Sequence
KEGYLVSKSTGCKYECLKLGDNDYCLRECKQQYGKSSGGYCYAFACWCTHLYEQAVVWPLPNKTCN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Solution structure of native and recombinant expressed toxin CssII from the venom of the scorpion Centruroides suffusus suffusus, and their effects on Nav1.5 Sodium channels.
pubmed doi rcsb
molecule tags Toxin
molecule keywords Beta-mammal toxin Css2
total genus 11
structure length 66
sequence length 66
ec nomenclature
pdb deposition date 2011-08-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00537 Toxin_3 Scorpion toxin-like domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.30.10 Alpha Beta 2-Layer Sandwich Defensin A-like Knottin, scorpion toxin-like 2li7A00
1C56A 2KYQA 2LT8A 1ZYVA 2LJ7A 1ZU3A 1WT7A 3E7RL 1PE4A 1FH3A 1JZAA 4V1DC 1OZZA 4AB0A 2M8BB 1NPIA 4HE7A 2KGQA 4UJ0A 2KJAA 2N2RA 2BRZA 1SN4A 2YBRC 1L4VA 2N2QA 1GPSA 4CQKA 4KYPA 2LY6A 1AYJA 2KBKA 1JKZA 1NE5A 1KV0A 1SNBA 2KBJA 1ICAA 1SEGA 2A7TA 1SN1A 1LQIA 1VNBA 1B7DA 2SN3A 1BCGA 1T0ZA 2ATBA 1BRZA 2E0HA 2YC1C 1CHZA 2KPYA 2E3FA 2LR3A 1MYNA 1P00A 1LQQA 1PTXA 5KK4A 2I61A 1NRAA 1ZFUA 1ZVEA 2LI7A 1JXCA 2N66A 2N69A 1TI5A 5CY0A 4AEIA 2ASCA 1NH5A 3E7UX 2KSKA 1I6FA 2E3GA 1CN2A 1WMTA 1I6GA 1MR4A 1ZVGA 1WWNA 1OMYA 4AAZA 1T7BA 1ZUTA 2LY5A 1LQHA 1P0AA 1T7EA 1C55A 1ZYWA 1NRBA 2NY8X 2NY9X 1DQ7A 2MZ0A 1T7AA 2B3CA 2LKBA 1PX9A 2KBHA 1I2VA 1B3CA 2LJMA 4HHFA 1GPTA 1I2UA 1N4NA 1AHOA 3PSMA 1T1TA 1BK8A 1DJTA 1JZBA 1BMRA 2YEOA 2B68A 2GL1A 1VNAA
chains in the Genus database with same CATH superfamily
1C56A 2KYQA 2LT8A 3QFUA 1ZYVA 2LJ7A 3D2FA 2MBKA 1NGBA 1UGLA 1NGHA 1ZU3A 2E88A 1WT7A 5EX5A 3E7RL 3KOZA 4GNIA 1PE4A 3M3ZA 1S3XA 4UAEF 1FH3A 3D2EB 1JZAA 4V1DC 5F0XA 2E8AA 5BPLA 1OZZA 4AB0A 1BA1A 2M8BB 1NPIA 4HE7A 2KGQA 4UJ0A 3CW4A 2KJAA 2N2RA 2BRZA 3L6QA 2YIOA 1SN4A 2YBRC 1L4VA 3FZMA 2N2QA 3QI7A 3FZHA 1GPSA 4CQKA 3LDQA 4H5TA 4KYPA 3KVGA 2LY6A 2QWMA 2KBKA 3A8YA 1AYJA 1JKZA 3C7NA 1NE5A 5AQIA 1KV0A 5AQHA 1SNBA 2KBJA 1ICAA 3L56A 3LDPA 5AQFA 5EXWA 1SEGA 5AQLA 2A7TA 5AQRA 1SN1A 1LQIA 1YUWA 1VNBA 1B7DA 2BUPA 2E2FA 3FZFA 3KOXA 4IO8A 5AQOA 1HPMA 2SN3A 1ATSA 1BCGA 3D2EA 1NGCA 1T0ZA 3LDOA 3QMLA 1NGIA 4FL9A 1K8BA 1POIA 1NGEA 5F2RA 3CQXA 2ATBA 2LN8A 1ATRA 5AQKA 3ATUA 2QWNA 4FSVA 5AQXA 5AQUA 5FPMA 5BN9A 5F1XA 5BPNA 1BRZA 3JXUA 1NGAA 2E0HA 2YC1C 3GL1A 5EVZA 1CHZA 5EY4A 2KPYA 2V7ZA 2E3FA 2LR3A 4H5RA 1MYNA 5AQTA 1P00A 2QW9A 1LQQA 1PTXA 1KAYA 5KK4A 2I61A 1NRAA 1ZFUA 5AQPA 1DKGD 3HSCA 3LDNA 1ZVEA 3FZLA 5FPDA 2LI7A 1HX1A 1JXCA 3R2VA 2K35A 2N66A 3KP0A 2N69A 5AQQA 5AQSA 1TI5A 4KBOA 5CY0A 4AEIA 2ASCA 4UAFE 1NH5A 3KOYA 3E7UX 3ATVA 2G2KA 2KSKA 3GKUA 5AQGA 3IUCA 2QWLA 3FZKA 5AQZA 1I6FA 1NGGA 1NGDA 1NGFA 2E3GA 1CN2A 3BK3C 4UADE 1WMTA 1I6GA 1KAXA 1XRSB 1MR4A 1ZVGA 1WWNA 1OMYA 4AAZA 1NGJA 2QWOA 5AQJA 1T7BA 5AR0A 3AY9A 1ZUTA 2LY5A 2YIPA 3KHWA 4H5WA 1LQHA 1P0AA 1T7EA 1C55A 1ZYWA 3D2FB 1NRBA 2NY8X 1QQNA 3GDQA 3LDLA 2NY9X 5BPMA 3SF4D 5FPNA 3L4IA 1BA0A 1BUPA 4H5VA 2JDQD 1DQ7A 2MZ0A 1QQMA 1T7AA 3KC6A 2B3CA 4HWIA 1QQOA 2QWQA 2KHOA 2LKBA 3KOWA 1PX9A 2KBHA 3FE1A 4H5NA 1I2VA 1KAZA 5FPEA 1B3CA 2LJMA 4HHFA 2QWRA 5BN8A 1GPTA 5AQVA 1I2UA 5AQWA 1N4NA 1AHOA 3PSMA 1T1TA 5AQNA 2QWPA 1DJTA 2YILA 1BK8A 1JZBA 3KP1A 5AQMA 5AQYA 1BMRA 2GMOA 3C7NB 2YEOA 2B68A 3I33A 1HJOA 2QXLA 3QFPA 2VY6A 2GL1A 1VNAA 2MN5A 2D56A
chains in the Genus database with same CATH topology
1C56A 2KYQA 2LT8A 1ZYVA 2LJ7A 1ZU3A 1WT7A 3E7RL 1PE4A 1FH3A 1JZAA 4V1DC 1OZZA 4AB0A 2M8BB 1NPIA 4HE7A 2KGQA 4UJ0A 2KJAA 2N2RA 2BRZA 1SN4A 2YBRC 1L4VA 2N2QA 1GPSA 4CQKA 4KYPA 2LY6A 1AYJA 2KBKA 1JKZA 1NE5A 1KV0A 1SNBA 2KBJA 1ICAA 1SEGA 2A7TA 1SN1A 1LQIA 1VNBA 1B7DA 2SN3A 1BCGA 1T0ZA 2ATBA 1BRZA 2E0HA 2YC1C 1CHZA 2KPYA 2E3FA 2LR3A 1MYNA 1P00A 1LQQA 1PTXA 5KK4A 2I61A 1NRAA 1ZFUA 1ZVEA 2LI7A 1JXCA 2N66A 2N69A 1TI5A 5CY0A 4AEIA 2ASCA 1NH5A 3E7UX 2KSKA 1I6FA 2E3GA 1CN2A 1WMTA 1I6GA 1MR4A 1ZVGA 1WWNA 1OMYA 4AAZA 1T7BA 1ZUTA 2LY5A 1LQHA 1P0AA 1T7EA 1C55A 1ZYWA 1NRBA 2NY8X 2NY9X 1DQ7A 2MZ0A 1T7AA 2B3CA 2LKBA 1PX9A 2KBHA 1I2VA 1B3CA 2LJMA 4HHFA 1GPTA 1I2UA 1N4NA 1AHOA 3PSMA 1T1TA 1BK8A 1DJTA 1JZBA 1BMRA 2YEOA 2B68A 2GL1A 1VNAA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1C56 A;  2KYQ A;  2LT8 A;  1ZYV A;  2LJ7 A;  1ZU3 A;  1WT7 A;  3E7R L;  1PE4 A;  1FH3 A;  1JZA A;  4V1D C;  1OZZ A;  4AB0 A;  2M8B B;  1NPI A;  4HE7 A;  2KGQ A;  4UJ0 A;  2KJA A;  2N2R A;  2BRZ A;  1SN4 A;  2YBR C;  1L4V A;  2N2Q A;  1GPS A;  4CQK A;  4KYP A;  2LY6 A;  1AYJ A;  2KBK A;  1JKZ A;  1NE5 A;  1KV0 A;  1SNB A;  2KBJ A;  1ICA A;  1SEG A;  2A7T A;  1SN1 A;  1LQI A;  1VNB A;  1B7D A;  2SN3 A;  1BCG A;  1T0Z A;  2ATB A;  1BRZ A;  2E0H A;  2YC1 C;  1CHZ A;  2KPY A;  2E3F A;  2LR3 A;  1MYN A;  1P00 A;  1LQQ A;  1PTX A;  5KK4 A;  2I61 A;  1NRA A;  1ZFU A;  1ZVE A;  2LI7 A;  1JXC A;  2N66 A;  2N69 A;  1TI5 A;  5CY0 A;  4AEI A;  2ASC A;  1NH5 A;  3E7U X;  2KSK A;  1I6F A;  2E3G A;  1CN2 A;  1WMT A;  1I6G A;  1MR4 A;  1ZVG A;  1WWN A;  1OMY A;  4AAZ A;  1T7B A;  1ZUT A;  2LY5 A;  1LQH A;  1P0A A;  1T7E A;  1C55 A;  1ZYW A;  1NRB A;  2NY8 X;  2NY9 X;  1DQ7 A;  2MZ0 A;  1T7A A;  2B3C A;  2LKB A;  1PX9 A;  2KBH A;  1I2V A;  1B3C A;  2LJM A;  4HHF A;  1GPT A;  1I2U A;  1N4N A;  1AHO A;  3PSM A;  1T1T A;  1BK8 A;  1DJT A;  1JZB A;  1BMR A;  2YEO A;  2B68 A;  2GL1 A;  1VNA A; 
#chains in the Genus database with same CATH topology
 1C56 A;  2KYQ A;  2LT8 A;  3QFU A;  1ZYV A;  2LJ7 A;  3D2F A;  2MBK A;  1NGB A;  1UGL A;  1NGH A;  1ZU3 A;  2E88 A;  1WT7 A;  5EX5 A;  3E7R L;  3KOZ A;  4GNI A;  1PE4 A;  3M3Z A;  1S3X A;  4UAE F;  1FH3 A;  3D2E B;  1JZA A;  4V1D C;  5F0X A;  2E8A A;  5BPL A;  1OZZ A;  4AB0 A;  1BA1 A;  2M8B B;  1NPI A;  4HE7 A;  2KGQ A;  4UJ0 A;  3CW4 A;  2KJA A;  2N2R A;  2BRZ A;  3L6Q A;  2YIO A;  1SN4 A;  2YBR C;  1L4V A;  3FZM A;  2N2Q A;  3QI7 A;  3FZH A;  1GPS A;  4CQK A;  3LDQ A;  4H5T A;  4KYP A;  3KVG A;  2LY6 A;  2QWM A;  2KBK A;  3A8Y A;  1AYJ A;  1JKZ A;  3C7N A;  1NE5 A;  5AQI A;  1KV0 A;  5AQH A;  1SNB A;  2KBJ A;  1ICA A;  3L56 A;  3LDP A;  5AQF A;  5EXW A;  1SEG A;  5AQL A;  2A7T A;  5AQR A;  1SN1 A;  1LQI A;  1YUW A;  1VNB A;  1B7D A;  2BUP A;  2E2F A;  3FZF A;  3KOX A;  4IO8 A;  5AQO A;  1HPM A;  2SN3 A;  1ATS A;  1BCG A;  3D2E A;  1NGC A;  1T0Z A;  3LDO A;  3QML A;  1NGI A;  4FL9 A;  1K8B A;  1POI A;  1NGE A;  5F2R A;  3CQX A;  2ATB A;  2LN8 A;  1ATR A;  5AQK A;  3ATU A;  2QWN A;  4FSV A;  5AQX A;  5AQU A;  5FPM A;  5BN9 A;  5F1X A;  5BPN A;  1BRZ A;  3JXU A;  1NGA A;  2E0H A;  2YC1 C;  3GL1 A;  5EVZ A;  1CHZ A;  5EY4 A;  2KPY A;  2V7Z A;  2E3F A;  2LR3 A;  4H5R A;  1MYN A;  5AQT A;  1P00 A;  2QW9 A;  1LQQ A;  1PTX A;  1KAY A;  5KK4 A;  2I61 A;  1NRA A;  1ZFU A;  5AQP A;  1DKG D;  3HSC A;  3LDN A;  1ZVE A;  3FZL A;  5FPD A;  2LI7 A;  1HX1 A;  1JXC A;  3R2V A;  2K35 A;  2N66 A;  3KP0 A;  2N69 A;  5AQQ A;  5AQS A;  1TI5 A;  4KBO A;  5CY0 A;  4AEI A;  2ASC A;  4UAF E;  1NH5 A;  3KOY A;  3E7U X;  3ATV A;  2G2K A;  2KSK A;  3GKU A;  5AQG A;  3IUC A;  2QWL A;  3FZK A;  5AQZ A;  1I6F A;  1NGG A;  1NGD A;  1NGF A;  2E3G A;  1CN2 A;  3BK3 C;  4UAD E;  1WMT A;  1I6G A;  1KAX A;  1XRS B;  1MR4 A;  1ZVG A;  1WWN A;  1OMY A;  4AAZ A;  1NGJ A;  2QWO A;  5AQJ A;  1T7B A;  5AR0 A;  3AY9 A;  1ZUT A;  2LY5 A;  2YIP A;  3KHW A;  4H5W A;  1LQH A;  1P0A A;  1T7E A;  1C55 A;  1ZYW A;  3D2F B;  1NRB A;  2NY8 X;  1QQN A;  3GDQ A;  3LDL A;  2NY9 X;  5BPM A;  3SF4 D;  5FPN A;  3L4I A;  1BA0 A;  1BUP A;  4H5V A;  2JDQ D;  1DQ7 A;  2MZ0 A;  1QQM A;  1T7A A;  3KC6 A;  2B3C A;  4HWI A;  1QQO A;  2QWQ A;  2KHO A;  2LKB A;  3KOW A;  1PX9 A;  2KBH A;  3FE1 A;  4H5N A;  1I2V A;  1KAZ A;  5FPE A;  1B3C A;  2LJM A;  4HHF A;  2QWR A;  5BN8 A;  1GPT A;  5AQV A;  1I2U A;  5AQW A;  1N4N A;  1AHO A;  3PSM A;  1T1T A;  5AQN A;  2QWP A;  1DJT A;  2YIL A;  1BK8 A;  1JZB A;  3KP1 A;  5AQM A;  5AQY A;  1BMR A;  2GMO A;  3C7N B;  2YEO A;  2B68 A;  3I33 A;  1HJO A;  2QXL A;  3QFP A;  2VY6 A;  2GL1 A;  1VNA A;  2MN5 A;  2D56 A; 
#chains in the Genus database with same CATH homology
 1C56 A;  2KYQ A;  2LT8 A;  1ZYV A;  2LJ7 A;  1ZU3 A;  1WT7 A;  3E7R L;  1PE4 A;  1FH3 A;  1JZA A;  4V1D C;  1OZZ A;  4AB0 A;  2M8B B;  1NPI A;  4HE7 A;  2KGQ A;  4UJ0 A;  2KJA A;  2N2R A;  2BRZ A;  1SN4 A;  2YBR C;  1L4V A;  2N2Q A;  1GPS A;  4CQK A;  4KYP A;  2LY6 A;  1AYJ A;  2KBK A;  1JKZ A;  1NE5 A;  1KV0 A;  1SNB A;  2KBJ A;  1ICA A;  1SEG A;  2A7T A;  1SN1 A;  1LQI A;  1VNB A;  1B7D A;  2SN3 A;  1BCG A;  1T0Z A;  2ATB A;  1BRZ A;  2E0H A;  2YC1 C;  1CHZ A;  2KPY A;  2E3F A;  2LR3 A;  1MYN A;  1P00 A;  1LQQ A;  1PTX A;  5KK4 A;  2I61 A;  1NRA A;  1ZFU A;  1ZVE A;  2LI7 A;  1JXC A;  2N66 A;  2N69 A;  1TI5 A;  5CY0 A;  4AEI A;  2ASC A;  1NH5 A;  3E7U X;  2KSK A;  1I6F A;  2E3G A;  1CN2 A;  1WMT A;  1I6G A;  1MR4 A;  1ZVG A;  1WWN A;  1OMY A;  4AAZ A;  1T7B A;  1ZUT A;  2LY5 A;  1LQH A;  1P0A A;  1T7E A;  1C55 A;  1ZYW A;  1NRB A;  2NY8 X;  2NY9 X;  1DQ7 A;  2MZ0 A;  1T7A A;  2B3C A;  2LKB A;  1PX9 A;  2KBH A;  1I2V A;  1B3C A;  2LJM A;  4HHF A;  1GPT A;  1I2U A;  1N4N A;  1AHO A;  3PSM A;  1T1T A;  1BK8 A;  1DJT A;  1JZB A;  1BMR A;  2YEO A;  2B68 A;  2GL1 A;  1VNA A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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