2LI7A

Solution structure of cssii
Total Genus 11
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
11
sequence length
66
structure length
66
Chain Sequence
KEGYLVSKSTGCKYECLKLGDNDYCLRECKQQYGKSSGGYCYAFACWCTHLYEQAVVWPLPNKTCN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Solution structure of native and recombinant expressed toxin CssII from the venom of the scorpion Centruroides suffusus suffusus, and their effects on Nav1.5 Sodium channels.
pubmed doi rcsb
molecule tags Toxin
molecule keywords Beta-mammal toxin Css2
total genus 11
structure length 66
sequence length 66
ec nomenclature
pdb deposition date 2011-08-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00537 Toxin_3 Scorpion toxin-like domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.30.10 Alpha Beta 2-Layer Sandwich Defensin A-like Knottin, scorpion toxin-like 2li7A00
1VNBA 1KV0A 1OMYA 1B3CA 1TI5A 2E3GA 1ICAA 3E7UX 1GPSA 1AHOA 1OZZA 2N66A 2KBKA 2GL1A 1GPTA 2YC1C 1MYNA 1ZFUA 5CY0A 2ASCA 1NH5A 2A7TA 1BCGA 2LY5A 1DJTA 2KBHA 1ZYWA 4HHFA 4AB0A 1LQHA 3E7RL 1ZYVA 2B3CA 1NE5A 1C55A 2LR3A 1P0AA 4CQKA 1I6GA 2LT8A 1SN4A 1T0ZA 2N69A 2ATBA 1CHZA 4AEIA 1LQIA 1WMTA 2N2RA 1PX9A 2E3FA 2YBRC 1B7DA 1I2UA 2NY8X 2SN3A 2YEOA 1T1TA 2KJAA 4AAZA 1NPIA 2BRZA 1SNBA 1WWNA 1JXCA 1N4NA 4HE7A 1FH3A 1SN1A 1JZBA 1ZVEA 1VNAA 1ZU3A 1MR4A 2N2QA 1AYJA 1I2VA 2NY9X 2B68A 1NRAA 1JZAA 1NRBA 2MZ0A 1PE4A 1JKZA 1P00A 2M8BB 2E0HA 1BK8A 1I6FA 1ZUTA 3PSMA 2KPYA 2KYQA 4KYPA 1T7BA 1BMRA 1T7AA 1PTXA 1ZVGA 1L4VA 1SEGA 2LI7A 1WT7A 2KSKA 2LJ7A 1T7EA 4V1DC 1CN2A 1C56A 2KGQA 2LJMA 1DQ7A 2LKBA 1LQQA 2KBJA 2LY6A 2I61A 5KK4A 4UJ0A 1BRZA
chains in the Genus database with same CATH superfamily
4UAFE 2QWRA 1VNBA 1KV0A 1NGHA 1BA1A 2YIOA 1NGJA 3D2FB 3IUCA 3LDQA 5AQGA 1OMYA 1NGAA 3GL1A 1B3CA 1TI5A 4H5WA 5AQQA 3FE1A 3FZMA 2E3GA 2E2FA 1QQNA 2MN5A 3E7UX 3KHWA 3KP0A 5AQLA 1GPSA 1ICAA 2V7ZA 1AHOA 4UAEF 1OZZA 2YILA 2N66A 3D2EA 2KBKA 2GL1A 2KHOA 1GPTA 2YC1C 5BN9A 1POIA 3C7NB 1ATRA 1MYNA 1KAZA 3D2EB 5AQVA 1ZFUA 2QWNA 5BPLA 5AQOA 1HPMA 2ASCA 3QMLA 1NH5A 2QW9A 3CQXA 5BPNA 5CY0A 2A7TA 1BCGA 4UADE 3D2FA 2LY5A 5AQUA 1DJTA 5AR0A 2LN8A 5FPEA 1NGDA 3ATUA 2E88A 2KBHA 2QWMA 3LDOA 1ZYWA 4FSVA 5AQJA 3BK3C 4H5VA 3LDPA 5EX5A 4HHFA 4AB0A 1LQHA 3E7RL 3FZKA 5AQXA 1ZYVA 2B3CA 1XRSB 1NE5A 3L56A 1C55A 1HJOA 3KP1A 5AQNA 2LR3A 5AQRA 1YUWA 1P0AA 1NGCA 2E8AA 4CQKA 1I6GA 2LT8A 3L6QA 4KBOA 1SN4A 1KAXA 1T0ZA 2K35A 1BA0A 2N69A 2VY6A 3LDNA 2ATBA 3AY9A 3KOYA 1CHZA 3JXUA 4H5RA 4H5TA 5AQMA 1LQIA 1WMTA 4AEIA 2N2RA 2QWOA 2MBKA 1PX9A 2QWPA 3LDLA 3QFPA 2JDQD 2E3FA 3FZLA 5AQHA 2YBRC 1B7DA 5AQYA 1I2UA 2NY8X 2SN3A 5F1XA 2YEOA 1T1TA 2KJAA 4AAZA 1NPIA 1NGGA 2BRZA 1SNBA 1WWNA 3QFUA 2BUPA 2QWLA 1JXCA 5AQFA 5EY4A 1N4NA 2QWQA 4HE7A 3GKUA 4IO8A 1BRZA 1FH3A 3ATVA 3HSCA 1SN1A 5FPDA 3I33A 1K8BA 1JZBA 5BN8A 1UGLA 1ATSA 1ZVEA 3KC6A 3FZHA 5AQIA 3SF4D 5EXWA 1VNAA 1ZU3A 1MR4A 1HX1A 2N2QA 2D56A 4GNIA 1AYJA 1I2VA 2NY9X 1NGFA 2B68A 4FL9A 1NRAA 1JZAA 1NRBA 5FPMA 3QI7A 2MZ0A 5AQKA 3KVGA 5BPMA 1PE4A 1JKZA 1P00A 2M8BB 2E0HA 3KOWA 4HWIA 1NGEA 1BK8A 1I6FA 3CW4A 5AQTA 5AQWA 1ZUTA 1QQOA 1NGIA 2YIPA 3PSMA 1BUPA 2KPYA 1NGBA 2KYQA 4KYPA 1T7BA 1BMRA 1T7AA 2G2KA 3FZFA 1PTXA 1ZVGA 1L4VA 1QQMA 1SEGA 2LI7A 1WT7A 2KSKA 1DKGD 2QXLA 3R2VA 5EVZA 5F2RA 5F0XA 3KOXA 2LJ7A 3L4IA 3M3ZA 1T7EA 4V1DC 1CN2A 1C56A 2KGQA 2LJMA 1DQ7A 1KAYA 1S3XA 2LKBA 3A8YA 1LQQA 5AQPA 3C7NA 2KBJA 2LY6A 2I61A 5KK4A 3KOZA 5AQZA 4UJ0A 3GDQA 5AQSA 4H5NA 2GMOA 5FPNA
chains in the Genus database with same CATH topology
1VNBA 1KV0A 1OMYA 1B3CA 1TI5A 2E3GA 1ICAA 3E7UX 1GPSA 1AHOA 1OZZA 2N66A 2KBKA 2GL1A 1GPTA 2YC1C 1MYNA 1ZFUA 5CY0A 2ASCA 1NH5A 2A7TA 1BCGA 2LY5A 1DJTA 2KBHA 1ZYWA 4HHFA 4AB0A 1LQHA 3E7RL 1ZYVA 2B3CA 1NE5A 1C55A 2LR3A 1P0AA 4CQKA 1I6GA 2LT8A 1SN4A 1T0ZA 2N69A 2ATBA 1CHZA 4AEIA 1LQIA 1WMTA 2N2RA 1PX9A 2E3FA 2YBRC 1B7DA 1I2UA 2NY8X 2SN3A 2YEOA 1T1TA 2KJAA 4AAZA 1NPIA 2BRZA 1SNBA 1WWNA 1JXCA 1N4NA 4HE7A 1FH3A 1SN1A 1JZBA 1ZVEA 1VNAA 1ZU3A 1MR4A 2N2QA 1AYJA 1I2VA 2NY9X 2B68A 1NRAA 1JZAA 1NRBA 2MZ0A 1PE4A 1JKZA 1P00A 2M8BB 2E0HA 1BK8A 1I6FA 1ZUTA 3PSMA 2KPYA 2KYQA 4KYPA 1T7BA 1BMRA 1T7AA 1PTXA 1ZVGA 1L4VA 1SEGA 2LI7A 1WT7A 2KSKA 2LJ7A 1T7EA 4V1DC 1CN2A 1C56A 2KGQA 2LJMA 1DQ7A 2LKBA 1LQQA 2KBJA 2LY6A 2I61A 5KK4A 4UJ0A 1BRZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1VNB A;  1KV0 A;  1OMY A;  1B3C A;  1TI5 A;  2E3G A;  1ICA A;  3E7U X;  1GPS A;  1AHO A;  1OZZ A;  2N66 A;  2KBK A;  2GL1 A;  1GPT A;  2YC1 C;  1MYN A;  1ZFU A;  5CY0 A;  2ASC A;  1NH5 A;  2A7T A;  1BCG A;  2LY5 A;  1DJT A;  2KBH A;  1ZYW A;  4HHF A;  4AB0 A;  1LQH A;  3E7R L;  1ZYV A;  2B3C A;  1NE5 A;  1C55 A;  2LR3 A;  1P0A A;  4CQK A;  1I6G A;  2LT8 A;  1SN4 A;  1T0Z A;  2N69 A;  2ATB A;  1CHZ A;  4AEI A;  1LQI A;  1WMT A;  2N2R A;  1PX9 A;  2E3F A;  2YBR C;  1B7D A;  1I2U A;  2NY8 X;  2SN3 A;  2YEO A;  1T1T A;  2KJA A;  4AAZ A;  1NPI A;  2BRZ A;  1SNB A;  1WWN A;  1JXC A;  1N4N A;  4HE7 A;  1FH3 A;  1SN1 A;  1JZB A;  1ZVE A;  1VNA A;  1ZU3 A;  1MR4 A;  2N2Q A;  1AYJ A;  1I2V A;  2NY9 X;  2B68 A;  1NRA A;  1JZA A;  1NRB A;  2MZ0 A;  1PE4 A;  1JKZ A;  1P00 A;  2M8B B;  2E0H A;  1BK8 A;  1I6F A;  1ZUT A;  3PSM A;  2KPY A;  2KYQ A;  4KYP A;  1T7B A;  1BMR A;  1T7A A;  1PTX A;  1ZVG A;  1L4V A;  1SEG A;  2LI7 A;  1WT7 A;  2KSK A;  2LJ7 A;  1T7E A;  4V1D C;  1CN2 A;  1C56 A;  2KGQ A;  2LJM A;  1DQ7 A;  2LKB A;  1LQQ A;  2KBJ A;  2LY6 A;  2I61 A;  5KK4 A;  4UJ0 A;  1BRZ A; 
#chains in the Genus database with same CATH topology
 4UAF E;  2QWR A;  1VNB A;  1KV0 A;  1NGH A;  1BA1 A;  2YIO A;  1NGJ A;  3D2F B;  3IUC A;  3LDQ A;  5AQG A;  1OMY A;  1NGA A;  3GL1 A;  1B3C A;  1TI5 A;  4H5W A;  5AQQ A;  3FE1 A;  3FZM A;  2E3G A;  2E2F A;  1QQN A;  2MN5 A;  3E7U X;  3KHW A;  3KP0 A;  5AQL A;  1GPS A;  1ICA A;  2V7Z A;  1AHO A;  4UAE F;  1OZZ A;  2YIL A;  2N66 A;  3D2E A;  2KBK A;  2GL1 A;  2KHO A;  1GPT A;  2YC1 C;  5BN9 A;  1POI A;  3C7N B;  1ATR A;  1MYN A;  1KAZ A;  3D2E B;  5AQV A;  1ZFU A;  2QWN A;  5BPL A;  5AQO A;  1HPM A;  2ASC A;  3QML A;  1NH5 A;  2QW9 A;  3CQX A;  5BPN A;  5CY0 A;  2A7T A;  1BCG A;  4UAD E;  3D2F A;  2LY5 A;  5AQU A;  1DJT A;  5AR0 A;  2LN8 A;  5FPE A;  1NGD A;  3ATU A;  2E88 A;  2KBH A;  2QWM A;  3LDO A;  1ZYW A;  4FSV A;  5AQJ A;  3BK3 C;  4H5V A;  3LDP A;  5EX5 A;  4HHF A;  4AB0 A;  1LQH A;  3E7R L;  3FZK A;  5AQX A;  1ZYV A;  2B3C A;  1XRS B;  1NE5 A;  3L56 A;  1C55 A;  1HJO A;  3KP1 A;  5AQN A;  2LR3 A;  5AQR A;  1YUW A;  1P0A A;  1NGC A;  2E8A A;  4CQK A;  1I6G A;  2LT8 A;  3L6Q A;  4KBO A;  1SN4 A;  1KAX A;  1T0Z A;  2K35 A;  1BA0 A;  2N69 A;  2VY6 A;  3LDN A;  2ATB A;  3AY9 A;  3KOY A;  1CHZ A;  3JXU A;  4H5R A;  4H5T A;  5AQM A;  1LQI A;  1WMT A;  4AEI A;  2N2R A;  2QWO A;  2MBK A;  1PX9 A;  2QWP A;  3LDL A;  3QFP A;  2JDQ D;  2E3F A;  3FZL A;  5AQH A;  2YBR C;  1B7D A;  5AQY A;  1I2U A;  2NY8 X;  2SN3 A;  5F1X A;  2YEO A;  1T1T A;  2KJA A;  4AAZ A;  1NPI A;  1NGG A;  2BRZ A;  1SNB A;  1WWN A;  3QFU A;  2BUP A;  2QWL A;  1JXC A;  5AQF A;  5EY4 A;  1N4N A;  2QWQ A;  4HE7 A;  3GKU A;  4IO8 A;  1BRZ A;  1FH3 A;  3ATV A;  3HSC A;  1SN1 A;  5FPD A;  3I33 A;  1K8B A;  1JZB A;  5BN8 A;  1UGL A;  1ATS A;  1ZVE A;  3KC6 A;  3FZH A;  5AQI A;  3SF4 D;  5EXW A;  1VNA A;  1ZU3 A;  1MR4 A;  1HX1 A;  2N2Q A;  2D56 A;  4GNI A;  1AYJ A;  1I2V A;  2NY9 X;  1NGF A;  2B68 A;  4FL9 A;  1NRA A;  1JZA A;  1NRB A;  5FPM A;  3QI7 A;  2MZ0 A;  5AQK A;  3KVG A;  5BPM A;  1PE4 A;  1JKZ A;  1P00 A;  2M8B B;  2E0H A;  3KOW A;  4HWI A;  1NGE A;  1BK8 A;  1I6F A;  3CW4 A;  5AQT A;  5AQW A;  1ZUT A;  1QQO A;  1NGI A;  2YIP A;  3PSM A;  1BUP A;  2KPY A;  1NGB A;  2KYQ A;  4KYP A;  1T7B A;  1BMR A;  1T7A A;  2G2K A;  3FZF A;  1PTX A;  1ZVG A;  1L4V A;  1QQM A;  1SEG A;  2LI7 A;  1WT7 A;  2KSK A;  1DKG D;  2QXL A;  3R2V A;  5EVZ A;  5F2R A;  5F0X A;  3KOX A;  2LJ7 A;  3L4I A;  3M3Z A;  1T7E A;  4V1D C;  1CN2 A;  1C56 A;  2KGQ A;  2LJM A;  1DQ7 A;  1KAY A;  1S3X A;  2LKB A;  3A8Y A;  1LQQ A;  5AQP A;  3C7N A;  2KBJ A;  2LY6 A;  2I61 A;  5KK4 A;  3KOZ A;  5AQZ A;  4UJ0 A;  3GDQ A;  5AQS A;  4H5N A;  2GMO A;  5FPN A; 
#chains in the Genus database with same CATH homology
 1VNB A;  1KV0 A;  1OMY A;  1B3C A;  1TI5 A;  2E3G A;  1ICA A;  3E7U X;  1GPS A;  1AHO A;  1OZZ A;  2N66 A;  2KBK A;  2GL1 A;  1GPT A;  2YC1 C;  1MYN A;  1ZFU A;  5CY0 A;  2ASC A;  1NH5 A;  2A7T A;  1BCG A;  2LY5 A;  1DJT A;  2KBH A;  1ZYW A;  4HHF A;  4AB0 A;  1LQH A;  3E7R L;  1ZYV A;  2B3C A;  1NE5 A;  1C55 A;  2LR3 A;  1P0A A;  4CQK A;  1I6G A;  2LT8 A;  1SN4 A;  1T0Z A;  2N69 A;  2ATB A;  1CHZ A;  4AEI A;  1LQI A;  1WMT A;  2N2R A;  1PX9 A;  2E3F A;  2YBR C;  1B7D A;  1I2U A;  2NY8 X;  2SN3 A;  2YEO A;  1T1T A;  2KJA A;  4AAZ A;  1NPI A;  2BRZ A;  1SNB A;  1WWN A;  1JXC A;  1N4N A;  4HE7 A;  1FH3 A;  1SN1 A;  1JZB A;  1ZVE A;  1VNA A;  1ZU3 A;  1MR4 A;  2N2Q A;  1AYJ A;  1I2V A;  2NY9 X;  2B68 A;  1NRA A;  1JZA A;  1NRB A;  2MZ0 A;  1PE4 A;  1JKZ A;  1P00 A;  2M8B B;  2E0H A;  1BK8 A;  1I6F A;  1ZUT A;  3PSM A;  2KPY A;  2KYQ A;  4KYP A;  1T7B A;  1BMR A;  1T7A A;  1PTX A;  1ZVG A;  1L4V A;  1SEG A;  2LI7 A;  1WT7 A;  2KSK A;  2LJ7 A;  1T7E A;  4V1D C;  1CN2 A;  1C56 A;  2KGQ A;  2LJM A;  1DQ7 A;  2LKB A;  1LQQ A;  2KBJ A;  2LY6 A;  2I61 A;  5KK4 A;  4UJ0 A;  1BRZ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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