2LJMA

Solution structure of cssii
Total Genus 5
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
5
sequence length
82
structure length
82
Chain Sequence
MRGSHHHHHHGSIEGRKEGYLVSKSTGCKYECLKLGDNDYCLRECKQQYGKSSGGYCYAFACWCTHLYEQAVVWPLPNKTCN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Solution structure of native and recombinant expressed toxin CssII from the venom of the scorpion Centruroides suffusus suffusus, and their effects on Nav1.5 Sodium channels.
pubmed doi rcsb
molecule tags Toxin
molecule keywords Beta-mammal toxin Css2
total genus 5
structure length 82
sequence length 82
ec nomenclature
pdb deposition date 2011-09-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00537 Toxin_3 Scorpion toxin-like domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.30.10 Alpha Beta 2-Layer Sandwich Defensin A-like Knottin, scorpion toxin-like 2ljmA01
1I6FA 2E3GA 2ASCA 4AEIA 1BCGA 1CHZA 2I61A 2KJAA 2ATBA 1ZYVA 2LR3A 1DJTA 4UJ0A 1DQ7A 1ZUTA 2LKBA 2BRZA 2E0HA 1LQIA 2N66A 1MR4A 1JXCA 1B3CA 1L4VA 2GL1A 1FH3A 3E7UX 1OZZA 2N69A 4CQKA 1GPTA 4AB0A 1T7BA 1TI5A 2YBRC 1N4NA 1AYJA 1VNAA 1JZAA 1SN4A 4V1DC 1WMTA 1NH5A 1NRAA 1OMYA 4HHFA 1ZVGA 2KPYA 1LQHA 1GPSA 4HE7A 2LT8A 1T7EA 1PX9A 1P0AA 1T7AA 2E3FA 2YEOA 1BK8A 1NRBA 1ZFUA 1BMRA 2LI7A 3PSMA 1SNBA 2B3CA 2KBJA 1C55A 1WWNA 3E7RL 1ICAA 1I2UA 1NE5A 1ZVEA 2KGQA 5CY0A 2N2QA 1SEGA 1ZU3A 2A7TA 1VNBA 2LJMA 1BRZA 2LY6A 1ZYWA 2NY8X 4AAZA 2KSKA 2LY5A 1AHOA 1I2VA 2NY9X 1CN2A 2KBHA 1MYNA 1I6GA 2LJ7A 1JKZA 1WT7A 1P00A 2B68A 2KYQA 2M8BB 1KV0A 1NPIA 2SN3A 1PE4A 1C56A 2YC1C 4KYPA 2KBKA 2MZ0A 1T0ZA 2N2RA 1JZBA 1B7DA 1SN1A 1T1TA 1PTXA 5KK4A 1LQQA
chains in the Genus database with same CATH superfamily
5FPNA 1I6FA 1NGFA 2E3GA 1NGJA 2ASCA 4AEIA 1BCGA 1HPMA 1CHZA 3LDQA 5AQSA 3FZKA 2I61A 1K8BA 3KOYA 2KJAA 4HWIA 2ATBA 1ZYVA 2LR3A 5F0XA 1DJTA 1NGGA 3LDLA 3QMLA 4UJ0A 1DQ7A 1KAYA 4IO8A 2QW9A 5AR0A 1ZUTA 1BUPA 3CW4A 1QQMA 2LKBA 2BRZA 3L6QA 3HSCA 3KOWA 3L4IA 1HJOA 1DKGD 2QWLA 3ATUA 3GL1A 4H5WA 5AQPA 2E0HA 1LQIA 2N66A 3D2EB 3KVGA 4H5RA 1MR4A 1JXCA 1B3CA 1L4VA 2GL1A 3A8YA 2QWRA 4KBOA 1FH3A 3E7UX 1OZZA 2N69A 1POIA 4CQKA 3JXUA 1T7BA 1TI5A 2YBRC 4AB0A 1KAZA 1QQNA 1N4NA 1S3XA 1VNAA 1QQOA 1AYJA 1NGCA 1JZAA 1GPTA 3FZMA 1SN4A 4V1DC 3LDNA 1WMTA 1NH5A 1NRAA 2GMOA 3FZFA 5AQFA 4UAEF 5AQUA 3BK3C 3D2EA 3I33A 1OMYA 2MN5A 4HHFA 1ZVGA 2KPYA 4H5TA 1LQHA 5AQTA 5EVZA 5AQYA 4GNIA 2YIPA 3IUCA 1GPSA 2BUPA 3R2VA 3KP1A 4HE7A 5EXWA 2LT8A 1T7EA 1PX9A 1NGBA 5AQWA 5BN8A 3QI7A 1P0AA 1T7AA 2E3FA 2YEOA 1BK8A 5BPLA 1NGAA 1NRBA 1ZFUA 2D56A 1BMRA 2LI7A 3SF4D 3ATVA 3AY9A 1NGEA 1XRSB 2QXLA 3PSMA 5F2RA 5BN9A 1SNBA 3KOXA 2B3CA 5AQJA 2QWNA 2KBJA 3QFUA 3LDOA 3M3ZA 1C55A 2QWMA 1WWNA 2V7ZA 3E7RL 5AQXA 5AQRA 1UGLA 2K35A 3LDPA 1ICAA 1I2UA 4UADE 1NE5A 1ZVEA 2KGQA 3GKUA 5CY0A 2YILA 2E2FA 3C7NB 2N2QA 5BPMA 1SEGA 1ZU3A 2A7TA 1VNBA 1NGHA 2LJMA 2YIOA 5BPNA 5FPDA 5AQVA 3KOZA 5FPEA 2E8AA 4H5NA 5AQZA 5EY4A 1BRZA 4FSVA 5FPMA 4FL9A 2LY6A 1ZYWA 1KAXA 2LN8A 2NY8X 5AQOA 2KSKA 2LY5A 1AHOA 4AAZA 1I2VA 2NY9X 3FE1A 1CN2A 3CQXA 1HX1A 2KBHA 3FZHA 1MYNA 5AQMA 1YUWA 2LJ7A 3D2FB 1JKZA 1I6GA 3C7NA 1WT7A 1P00A 2QWOA 5EX5A 2B68A 3KP0A 3L56A 1ATSA 5AQIA 1ATRA 2KYQA 5AQGA 2M8BB 3KHWA 1KV0A 5AQQA 2JDQD 2E88A 1NPIA 3GDQA 1NGIA 2SN3A 4UAFE 1PE4A 3FZLA 1C56A 2YC1C 4KYPA 2KBKA 2MZ0A 1T0ZA 3KC6A 3QFPA 1NGDA 5AQKA 1BA0A 2N2RA 4H5VA 1BA1A 2KHOA 1JZBA 5AQHA 1B7DA 5AQLA 1SN1A 2VY6A 2MBKA 3D2FA 5AQNA 5F1XA 1T1TA 1PTXA 2G2KA 5KK4A 2QWPA 1LQQA 2QWQA
chains in the Genus database with same CATH topology
1I6FA 2E3GA 2ASCA 4AEIA 1BCGA 1CHZA 2I61A 2KJAA 2ATBA 1ZYVA 2LR3A 1DJTA 4UJ0A 1DQ7A 1ZUTA 2LKBA 2BRZA 2E0HA 1LQIA 2N66A 1MR4A 1JXCA 1B3CA 1L4VA 2GL1A 1FH3A 3E7UX 1OZZA 2N69A 4CQKA 1GPTA 4AB0A 1T7BA 1TI5A 2YBRC 1N4NA 1AYJA 1VNAA 1JZAA 1SN4A 4V1DC 1WMTA 1NH5A 1NRAA 1OMYA 4HHFA 1ZVGA 2KPYA 1LQHA 1GPSA 4HE7A 2LT8A 1T7EA 1PX9A 1P0AA 1T7AA 2E3FA 2YEOA 1BK8A 1NRBA 1ZFUA 1BMRA 2LI7A 3PSMA 1SNBA 2B3CA 2KBJA 1C55A 1WWNA 3E7RL 1ICAA 1I2UA 1NE5A 1ZVEA 2KGQA 5CY0A 2N2QA 1SEGA 1ZU3A 2A7TA 1VNBA 2LJMA 1BRZA 2LY6A 1ZYWA 2NY8X 4AAZA 2KSKA 2LY5A 1AHOA 1I2VA 2NY9X 1CN2A 2KBHA 1MYNA 1I6GA 2LJ7A 1JKZA 1WT7A 1P00A 2B68A 2KYQA 2M8BB 1KV0A 1NPIA 2SN3A 1PE4A 1C56A 2YC1C 4KYPA 2KBKA 2MZ0A 1T0ZA 2N2RA 1JZBA 1B7DA 1SN1A 1T1TA 1PTXA 5KK4A 1LQQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1I6F A;  2E3G A;  2ASC A;  4AEI A;  1BCG A;  1CHZ A;  2I61 A;  2KJA A;  2ATB A;  1ZYV A;  2LR3 A;  1DJT A;  4UJ0 A;  1DQ7 A;  1ZUT A;  2LKB A;  2BRZ A;  2E0H A;  1LQI A;  2N66 A;  1MR4 A;  1JXC A;  1B3C A;  1L4V A;  2GL1 A;  1FH3 A;  3E7U X;  1OZZ A;  2N69 A;  4CQK A;  1GPT A;  4AB0 A;  1T7B A;  1TI5 A;  2YBR C;  1N4N A;  1AYJ A;  1VNA A;  1JZA A;  1SN4 A;  4V1D C;  1WMT A;  1NH5 A;  1NRA A;  1OMY A;  4HHF A;  1ZVG A;  2KPY A;  1LQH A;  1GPS A;  4HE7 A;  2LT8 A;  1T7E A;  1PX9 A;  1P0A A;  1T7A A;  2E3F A;  2YEO A;  1BK8 A;  1NRB A;  1ZFU A;  1BMR A;  2LI7 A;  3PSM A;  1SNB A;  2B3C A;  2KBJ A;  1C55 A;  1WWN A;  3E7R L;  1ICA A;  1I2U A;  1NE5 A;  1ZVE A;  2KGQ A;  5CY0 A;  2N2Q A;  1SEG A;  1ZU3 A;  2A7T A;  1VNB A;  2LJM A;  1BRZ A;  2LY6 A;  1ZYW A;  2NY8 X;  4AAZ A;  2KSK A;  2LY5 A;  1AHO A;  1I2V A;  2NY9 X;  1CN2 A;  2KBH A;  1MYN A;  1I6G A;  2LJ7 A;  1JKZ A;  1WT7 A;  1P00 A;  2B68 A;  2KYQ A;  2M8B B;  1KV0 A;  1NPI A;  2SN3 A;  1PE4 A;  1C56 A;  2YC1 C;  4KYP A;  2KBK A;  2MZ0 A;  1T0Z A;  2N2R A;  1JZB A;  1B7D A;  1SN1 A;  1T1T A;  1PTX A;  5KK4 A;  1LQQ A; 
#chains in the Genus database with same CATH topology
 5FPN A;  1I6F A;  1NGF A;  2E3G A;  1NGJ A;  2ASC A;  4AEI A;  1BCG A;  1HPM A;  1CHZ A;  3LDQ A;  5AQS A;  3FZK A;  2I61 A;  1K8B A;  3KOY A;  2KJA A;  4HWI A;  2ATB A;  1ZYV A;  2LR3 A;  5F0X A;  1DJT A;  1NGG A;  3LDL A;  3QML A;  4UJ0 A;  1DQ7 A;  1KAY A;  4IO8 A;  2QW9 A;  5AR0 A;  1ZUT A;  1BUP A;  3CW4 A;  1QQM A;  2LKB A;  2BRZ A;  3L6Q A;  3HSC A;  3KOW A;  3L4I A;  1HJO A;  1DKG D;  2QWL A;  3ATU A;  3GL1 A;  4H5W A;  5AQP A;  2E0H A;  1LQI A;  2N66 A;  3D2E B;  3KVG A;  4H5R A;  1MR4 A;  1JXC A;  1B3C A;  1L4V A;  2GL1 A;  3A8Y A;  2QWR A;  4KBO A;  1FH3 A;  3E7U X;  1OZZ A;  2N69 A;  1POI A;  4CQK A;  3JXU A;  1T7B A;  1TI5 A;  2YBR C;  4AB0 A;  1KAZ A;  1QQN A;  1N4N A;  1S3X A;  1VNA A;  1QQO A;  1AYJ A;  1NGC A;  1JZA A;  1GPT A;  3FZM A;  1SN4 A;  4V1D C;  3LDN A;  1WMT A;  1NH5 A;  1NRA A;  2GMO A;  3FZF A;  5AQF A;  4UAE F;  5AQU A;  3BK3 C;  3D2E A;  3I33 A;  1OMY A;  2MN5 A;  4HHF A;  1ZVG A;  2KPY A;  4H5T A;  1LQH A;  5AQT A;  5EVZ A;  5AQY A;  4GNI A;  2YIP A;  3IUC A;  1GPS A;  2BUP A;  3R2V A;  3KP1 A;  4HE7 A;  5EXW A;  2LT8 A;  1T7E A;  1PX9 A;  1NGB A;  5AQW A;  5BN8 A;  3QI7 A;  1P0A A;  1T7A A;  2E3F A;  2YEO A;  1BK8 A;  5BPL A;  1NGA A;  1NRB A;  1ZFU A;  2D56 A;  1BMR A;  2LI7 A;  3SF4 D;  3ATV A;  3AY9 A;  1NGE A;  1XRS B;  2QXL A;  3PSM A;  5F2R A;  5BN9 A;  1SNB A;  3KOX A;  2B3C A;  5AQJ A;  2QWN A;  2KBJ A;  3QFU A;  3LDO A;  3M3Z A;  1C55 A;  2QWM A;  1WWN A;  2V7Z A;  3E7R L;  5AQX A;  5AQR A;  1UGL A;  2K35 A;  3LDP A;  1ICA A;  1I2U A;  4UAD E;  1NE5 A;  1ZVE A;  2KGQ A;  3GKU A;  5CY0 A;  2YIL A;  2E2F A;  3C7N B;  2N2Q A;  5BPM A;  1SEG A;  1ZU3 A;  2A7T A;  1VNB A;  1NGH A;  2LJM A;  2YIO A;  5BPN A;  5FPD A;  5AQV A;  3KOZ A;  5FPE A;  2E8A A;  4H5N A;  5AQZ A;  5EY4 A;  1BRZ A;  4FSV A;  5FPM A;  4FL9 A;  2LY6 A;  1ZYW A;  1KAX A;  2LN8 A;  2NY8 X;  5AQO A;  2KSK A;  2LY5 A;  1AHO A;  4AAZ A;  1I2V A;  2NY9 X;  3FE1 A;  1CN2 A;  3CQX A;  1HX1 A;  2KBH A;  3FZH A;  1MYN A;  5AQM A;  1YUW A;  2LJ7 A;  3D2F B;  1JKZ A;  1I6G A;  3C7N A;  1WT7 A;  1P00 A;  2QWO A;  5EX5 A;  2B68 A;  3KP0 A;  3L56 A;  1ATS A;  5AQI A;  1ATR A;  2KYQ A;  5AQG A;  2M8B B;  3KHW A;  1KV0 A;  5AQQ A;  2JDQ D;  2E88 A;  1NPI A;  3GDQ A;  1NGI A;  2SN3 A;  4UAF E;  1PE4 A;  3FZL A;  1C56 A;  2YC1 C;  4KYP A;  2KBK A;  2MZ0 A;  1T0Z A;  3KC6 A;  3QFP A;  1NGD A;  5AQK A;  1BA0 A;  2N2R A;  4H5V A;  1BA1 A;  2KHO A;  1JZB A;  5AQH A;  1B7D A;  5AQL A;  1SN1 A;  2VY6 A;  2MBK A;  3D2F A;  5AQN A;  5F1X A;  1T1T A;  1PTX A;  2G2K A;  5KK4 A;  2QWP A;  1LQQ A;  2QWQ A; 
#chains in the Genus database with same CATH homology
 1I6F A;  2E3G A;  2ASC A;  4AEI A;  1BCG A;  1CHZ A;  2I61 A;  2KJA A;  2ATB A;  1ZYV A;  2LR3 A;  1DJT A;  4UJ0 A;  1DQ7 A;  1ZUT A;  2LKB A;  2BRZ A;  2E0H A;  1LQI A;  2N66 A;  1MR4 A;  1JXC A;  1B3C A;  1L4V A;  2GL1 A;  1FH3 A;  3E7U X;  1OZZ A;  2N69 A;  4CQK A;  1GPT A;  4AB0 A;  1T7B A;  1TI5 A;  2YBR C;  1N4N A;  1AYJ A;  1VNA A;  1JZA A;  1SN4 A;  4V1D C;  1WMT A;  1NH5 A;  1NRA A;  1OMY A;  4HHF A;  1ZVG A;  2KPY A;  1LQH A;  1GPS A;  4HE7 A;  2LT8 A;  1T7E A;  1PX9 A;  1P0A A;  1T7A A;  2E3F A;  2YEO A;  1BK8 A;  1NRB A;  1ZFU A;  1BMR A;  2LI7 A;  3PSM A;  1SNB A;  2B3C A;  2KBJ A;  1C55 A;  1WWN A;  3E7R L;  1ICA A;  1I2U A;  1NE5 A;  1ZVE A;  2KGQ A;  5CY0 A;  2N2Q A;  1SEG A;  1ZU3 A;  2A7T A;  1VNB A;  2LJM A;  1BRZ A;  2LY6 A;  1ZYW A;  2NY8 X;  4AAZ A;  2KSK A;  2LY5 A;  1AHO A;  1I2V A;  2NY9 X;  1CN2 A;  2KBH A;  1MYN A;  1I6G A;  2LJ7 A;  1JKZ A;  1WT7 A;  1P00 A;  2B68 A;  2KYQ A;  2M8B B;  1KV0 A;  1NPI A;  2SN3 A;  1PE4 A;  1C56 A;  2YC1 C;  4KYP A;  2KBK A;  2MZ0 A;  1T0Z A;  2N2R A;  1JZB A;  1B7D A;  1SN1 A;  1T1T A;  1PTX A;  5KK4 A;  1LQQ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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