2LN8A

The solution structure of theromacin
Total Genus 24
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
24
sequence length
75
structure length
75
Chain Sequence
GCFEDWSRCSPSTASATGVLWRSCDSYCKVCFKADRGECYDSPSLNCPHRLPNNKQCRCINARTAKDNRNPTCWA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Antimicrobial protein
source organism Hirudo medicinalis
publication title Macin family of antimicrobial proteins combines antimicrobial and nerve repair activities.
pubmed doi rcsb
molecule keywords Theromacin
total genus 24
structure length 75
sequence length 75
ec nomenclature
pdb deposition date 2011-12-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF14865 Macin Macin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.30.100 Alpha Beta 2-Layer Sandwich Defensin A-like Defensin A-like 2ln8A00
2LN8A 2K35A
chains in the Genus database with same CATH superfamily
3E7UX 3GDQA 5AQVA 3KOWA 5AQTA 4H5RA 1GPSA 1WMTA 1XRSB 3KHWA 5AQWA 1JXCA 1BCGA 2LY5A 4KBOA 5EXWA 5BPLA 1NGAA 1MR4A 2QWRA 5AQSA 1L4VA 2N66A 1BMRA 1C55A 1I2VA 2ATBA 1VNBA 5AQYA 1ZUTA 4GNIA 4HWIA 3KVGA 1NGBA 2NY9X 5AQQA 1AHOA 1CHZA 2E2FA 3KOZA 2KPYA 3FZFA 5BPNA 1B3CA 1JZBA 1OMYA 5EVZA 3LDNA 1T7EA 3CW4A 3LDQA 3GKUA 5FPEA 2KHOA 3C7NB 5AR0A 4UAEF 1ATRA 5F2RA 5BPMA 1I6GA 1NGGA 1BA1A 1NPIA 2KBKA 2NY8X 1BUPA 3QI7A 3KP1A 2V7ZA 4FSVA 5AQUA 4H5WA 4FL9A 4V1DC 1NGCA 5KK4A 1ZVEA 2ASCA 4H5VA 5AQGA 1MYNA 3AY9A 2LT8A 3ATVA 3JXUA 5AQHA 2B3CA 1P00A 1NGFA 3C7NA 3L56A 2G2KA 5AQOA 4IO8A 2BUPA 2E8AA 2KJAA 1KAXA 1JKZA 5FPMA 1BRZA 1NGJA 1POIA 1QQNA 2B68A 3CQXA 3FZLA 5AQJA 1FH3A 2GMOA 2QXLA 5AQZA 2JDQD 1OZZA 3I33A 1HPMA 2YEOA 5F1XA 2SN3A 1AYJA 1KAZA 1NH5A 2QWLA 1GPTA 1T0ZA 1YUWA 1SEGA 4AEIA 3LDPA 1DKGD 5AQNA 2YBRC 1ZVGA 1QQMA 2KGQA 1C56A 2KSKA 2MZ0A 3L6QA 1I2UA 2LKBA 2N2QA 2MBKA 2YIOA 3KP0A 1JZAA 1DQ7A 1NGHA 1PTXA 2VY6A 3FZKA 2E0HA 1HJOA 5AQPA 1ZU3A 1LQIA 2LI7A 2LR3A 3BK3C 2GL1A 1BA0A 2QWNA 2N2RA 2YILA 4H5NA 1BK8A 5AQIA 1ZYWA 5AQRA 2KBJA 3GL1A 1VNAA 2I61A 1I6FA 3D2EA 3QMLA 1LQHA 2QWMA 1P0AA 3HSCA 2E3FA 2KBHA 3ATUA 3D2FB 3LDLA 1ICAA 3KC6A 4KYPA 4HHFA 2LN8A 2YC1C 1QQOA 5EY4A 2QW9A 1SNBA 2QWOA 1LQQA 2LJMA 3KOXA 5FPDA 5AQMA 1T1TA 4AB0A 1T7AA 1NGIA 2N69A 1HX1A 3KOYA 3D2FA 1K8BA 1NRAA 2LY6A 3D2EB 2K35A 1T7BA 4UJ0A 5CY0A 1NE5A 4H5TA 3PSMA 1NGDA 1TI5A 1WT7A 4UADE 3QFPA 1ATSA 3IUCA 1DJTA 5AQKA 2E3GA 1NGEA 3FZMA 5AQLA 3M3ZA 2BRZA 3E7RL 5EX5A 2KYQA 5BN9A 1ZFUA 3L4IA 1PE4A 1PX9A 2QWQA 3FE1A 3LDOA 4AAZA 2YIPA 5BN8A 2E88A 1CN2A 1UGLA 5F0XA 1ZYVA 1N4NA 2QWPA 2D56A 3FZHA 5AQFA 4HE7A 2LJ7A 1KV0A 3A8YA 2A7TA 3QFUA 1NRBA 4CQKA 1KAYA 1B7DA 1SN1A 4UAFE 5AQXA 1S3XA 2M8BB 2MN5A 1SN4A 3R2VA 3SF4D 5FPNA 1WWNA
chains in the Genus database with same CATH topology
3GDQA 5AQVA 5AQTA 4H5RA 3KHWA 5AQWA 4KBOA 5EXWA 5BPLA 1NGAA 2QWRA 5AQSA 4GNIA 4HWIA 3KVGA 1NGBA 5AQQA 2E2FA 3FZFA 5BPNA 5EVZA 3LDNA 3CW4A 5FPEA 3LDQA 2KHOA 3C7NB 5AR0A 4UAEF 1ATRA 5F2RA 5BPMA 1NGGA 1BA1A 1BUPA 3QI7A 5AQUA 2V7ZA 4FSVA 4H5WA 4FL9A 1NGCA 5AQGA 4H5VA 3JXUA 3ATVA 5AQHA 1NGFA 3C7NA 3L56A 5AQOA 4IO8A 2BUPA 2E8AA 1KAXA 5FPMA 1NGJA 1POIA 1QQNA 5AQJA 3CQXA 3FZLA 2GMOA 2QXLA 5AQZA 2JDQD 3I33A 1HPMA 5F1XA 1KAZA 2QWLA 1YUWA 3LDPA 1DKGD 5AQNA 1QQMA 3L6QA 2YIOA 2MBKA 1NGHA 3FZKA 2VY6A 1HJOA 5AQPA 3BK3C 1BA0A 2QWNA 2YILA 4H5NA 5AQIA 5AQRA 3GL1A 3D2EA 3QMLA 2QWMA 3HSCA 3ATUA 3LDLA 3D2FB 3KC6A 2LN8A 1QQOA 5EY4A 2QW9A 2QWOA 5FPDA 5AQMA 1NGIA 1HX1A 3D2FA 3D2EB 2K35A 4H5TA 4UADE 1NGDA 5AQYA 3QFPA 1ATSA 3IUCA 5AQKA 3FZMA 1NGEA 5AQLA 3M3ZA 5EX5A 5BN9A 3L4IA 2QWQA 3FE1A 3LDOA 2YIPA 5BN8A 2E88A 5F0XA 5AQFA 2QWPA 2D56A 3FZHA 3A8YA 3QFUA 1KAYA 5AQXA 4UAFE 1S3XA 2MN5A 3R2VA 3SF4D 5FPNA 3AY9A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2LN8 A;  2K35 A; 
#chains in the Genus database with same CATH topology
 3E7U X;  3GDQ A;  5AQV A;  3KOW A;  5AQT A;  4H5R A;  1GPS A;  1WMT A;  1XRS B;  3KHW A;  5AQW A;  1JXC A;  1BCG A;  2LY5 A;  4KBO A;  5EXW A;  5BPL A;  1NGA A;  1MR4 A;  2QWR A;  5AQS A;  1L4V A;  2N66 A;  1BMR A;  1C55 A;  1I2V A;  2ATB A;  1VNB A;  5AQY A;  1ZUT A;  4GNI A;  4HWI A;  3KVG A;  1NGB A;  2NY9 X;  5AQQ A;  1AHO A;  1CHZ A;  2E2F A;  3KOZ A;  2KPY A;  3FZF A;  5BPN A;  1B3C A;  1JZB A;  1OMY A;  5EVZ A;  3LDN A;  1T7E A;  3CW4 A;  3LDQ A;  3GKU A;  5FPE A;  2KHO A;  3C7N B;  5AR0 A;  4UAE F;  1ATR A;  5F2R A;  5BPM A;  1I6G A;  1NGG A;  1BA1 A;  1NPI A;  2KBK A;  2NY8 X;  1BUP A;  3QI7 A;  3KP1 A;  2V7Z A;  4FSV A;  5AQU A;  4H5W A;  4FL9 A;  4V1D C;  1NGC A;  5KK4 A;  1ZVE A;  2ASC A;  4H5V A;  5AQG A;  1MYN A;  3AY9 A;  2LT8 A;  3ATV A;  3JXU A;  5AQH A;  2B3C A;  1P00 A;  1NGF A;  3C7N A;  3L56 A;  2G2K A;  5AQO A;  4IO8 A;  2BUP A;  2E8A A;  2KJA A;  1KAX A;  1JKZ A;  5FPM A;  1BRZ A;  1NGJ A;  1POI A;  1QQN A;  2B68 A;  3CQX A;  3FZL A;  5AQJ A;  1FH3 A;  2GMO A;  2QXL A;  5AQZ A;  2JDQ D;  1OZZ A;  3I33 A;  1HPM A;  2YEO A;  5F1X A;  2SN3 A;  1AYJ A;  1KAZ A;  1NH5 A;  2QWL A;  1GPT A;  1T0Z A;  1YUW A;  1SEG A;  4AEI A;  3LDP A;  1DKG D;  5AQN A;  2YBR C;  1ZVG A;  1QQM A;  2KGQ A;  1C56 A;  2KSK A;  2MZ0 A;  3L6Q A;  1I2U A;  2LKB A;  2N2Q A;  2MBK A;  2YIO A;  3KP0 A;  1JZA A;  1DQ7 A;  1NGH A;  1PTX A;  2VY6 A;  3FZK A;  2E0H A;  1HJO A;  5AQP A;  1ZU3 A;  1LQI A;  2LI7 A;  2LR3 A;  3BK3 C;  2GL1 A;  1BA0 A;  2QWN A;  2N2R A;  2YIL A;  4H5N A;  1BK8 A;  5AQI A;  1ZYW A;  5AQR A;  2KBJ A;  3GL1 A;  1VNA A;  2I61 A;  1I6F A;  3D2E A;  3QML A;  1LQH A;  2QWM A;  1P0A A;  3HSC A;  2E3F A;  2KBH A;  3ATU A;  3D2F B;  3LDL A;  1ICA A;  3KC6 A;  4KYP A;  4HHF A;  2LN8 A;  2YC1 C;  1QQO A;  5EY4 A;  2QW9 A;  1SNB A;  2QWO A;  1LQQ A;  2LJM A;  3KOX A;  5FPD A;  5AQM A;  1T1T A;  4AB0 A;  1T7A A;  1NGI A;  2N69 A;  1HX1 A;  3KOY A;  3D2F A;  1K8B A;  1NRA A;  2LY6 A;  3D2E B;  2K35 A;  1T7B A;  4UJ0 A;  5CY0 A;  1NE5 A;  4H5T A;  3PSM A;  1NGD A;  1TI5 A;  1WT7 A;  4UAD E;  3QFP A;  1ATS A;  3IUC A;  1DJT A;  5AQK A;  2E3G A;  1NGE A;  3FZM A;  5AQL A;  3M3Z A;  2BRZ A;  3E7R L;  5EX5 A;  2KYQ A;  5BN9 A;  1ZFU A;  3L4I A;  1PE4 A;  1PX9 A;  2QWQ A;  3FE1 A;  3LDO A;  4AAZ A;  2YIP A;  5BN8 A;  2E88 A;  1CN2 A;  1UGL A;  5F0X A;  1ZYV A;  1N4N A;  2QWP A;  2D56 A;  3FZH A;  5AQF A;  4HE7 A;  2LJ7 A;  1KV0 A;  3A8Y A;  2A7T A;  3QFU A;  1NRB A;  4CQK A;  1KAY A;  1B7D A;  1SN1 A;  4UAF E;  5AQX A;  1S3X A;  2M8B B;  2MN5 A;  1SN4 A;  3R2V A;  3SF4 D;  5FPN A;  1WWN A; 
#chains in the Genus database with same CATH homology
 3GDQ A;  5AQV A;  5AQT A;  4H5R A;  3KHW A;  5AQW A;  4KBO A;  5EXW A;  5BPL A;  1NGA A;  2QWR A;  5AQS A;  4GNI A;  4HWI A;  3KVG A;  1NGB A;  5AQQ A;  2E2F A;  3FZF A;  5BPN A;  5EVZ A;  3LDN A;  3CW4 A;  5FPE A;  3LDQ A;  2KHO A;  3C7N B;  5AR0 A;  4UAE F;  1ATR A;  5F2R A;  5BPM A;  1NGG A;  1BA1 A;  1BUP A;  3QI7 A;  5AQU A;  2V7Z A;  4FSV A;  4H5W A;  4FL9 A;  1NGC A;  5AQG A;  4H5V A;  3JXU A;  3ATV A;  5AQH A;  1NGF A;  3C7N A;  3L56 A;  5AQO A;  4IO8 A;  2BUP A;  2E8A A;  1KAX A;  5FPM A;  1NGJ A;  1POI A;  1QQN A;  5AQJ A;  3CQX A;  3FZL A;  2GMO A;  2QXL A;  5AQZ A;  2JDQ D;  3I33 A;  1HPM A;  5F1X A;  1KAZ A;  2QWL A;  1YUW A;  3LDP A;  1DKG D;  5AQN A;  1QQM A;  3L6Q A;  2YIO A;  2MBK A;  1NGH A;  3FZK A;  2VY6 A;  1HJO A;  5AQP A;  3BK3 C;  1BA0 A;  2QWN A;  2YIL A;  4H5N A;  5AQI A;  5AQR A;  3GL1 A;  3D2E A;  3QML A;  2QWM A;  3HSC A;  3ATU A;  3LDL A;  3D2F B;  3KC6 A;  2LN8 A;  1QQO A;  5EY4 A;  2QW9 A;  2QWO A;  5FPD A;  5AQM A;  1NGI A;  1HX1 A;  3D2F A;  3D2E B;  2K35 A;  4H5T A;  4UAD E;  1NGD A;  5AQY A;  3QFP A;  1ATS A;  3IUC A;  5AQK A;  3FZM A;  1NGE A;  5AQL A;  3M3Z A;  5EX5 A;  5BN9 A;  3L4I A;  2QWQ A;  3FE1 A;  3LDO A;  2YIP A;  5BN8 A;  2E88 A;  5F0X A;  5AQF A;  2QWP A;  2D56 A;  3FZH A;  3A8Y A;  3QFU A;  1KAY A;  5AQX A;  4UAF E;  1S3X A;  2MN5 A;  3R2V A;  3SF4 D;  5FPN A;  3AY9 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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