2LN8A

The solution structure of theromacin
Total Genus 24
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
24
sequence length
75
structure length
75
Chain Sequence
GCFEDWSRCSPSTASATGVLWRSCDSYCKVCFKADRGECYDSPSLNCPHRLPNNKQCRCINARTAKDNRNPTCWA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Macin family of antimicrobial proteins combines antimicrobial and nerve repair activities.
pubmed doi rcsb
molecule tags Antimicrobial protein
source organism Hirudo medicinalis
molecule keywords Theromacin
total genus 24
structure length 75
sequence length 75
ec nomenclature
pdb deposition date 2011-12-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF14865 Macin Macin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.30.100 Alpha Beta 2-Layer Sandwich Defensin A-like Defensin A-like 2ln8A00
2LN8A 2K35A
chains in the Genus database with same CATH superfamily
1ZYVA 1ZU3A 1NGBA 3FZFA 4H5RA 2LT8A 2QW9A 3D2FB 4AEIA 1P00A 1KAYA 1OZZA 3KHWA 3A8YA 1AYJA 3KP1A 1ZVGA 3FE1A 1ICAA 3IUCA 1SEGA 2JDQD 4IO8A 2I61A 1NRAA 1PE4A 1ATSA 2YBRC 1NGEA 1YUWA 5KK4A 1VNBA 1WWNA 3FZLA 4AB0A 1OMYA 1NGGA 4UJ0A 1ZVEA 1MYNA 3E7UX 1QQMA 2BUPA 1KAZA 1SN1A 3FZMA 3ATVA 1KV0A 1LQIA 2BRZA 2QWOA 5AR0A 3LDPA 2B3CA 1ZUTA 2LN8A 4UAEF 3JXUA 2KBJA 3LDLA 5AQKA 5AQWA 4AAZA 5AQNA 1NGDA 2G2KA 2YEOA 1T7AA 1NGCA 2KJAA 2MZ0A 2LKBA 3D2FA 5AQJA 1SN4A 3C7NA 5AQSA 5F1XA 1NGJA 4H5VA 1FH3A 4H5NA 1BUPA 2KBHA 2N66A 3FZKA 1UGLA 4HHFA 3AY9A 1B7DA 3CW4A 5EVZA 1ATRA 1SNBA 2LI7A 5AQXA 3KOWA 2E88A 5AQUA 3QMLA 1WT7A 5EY4A 3QI7A 1N4NA 1MR4A 2YC1C 2YILA 1BMRA 5AQQA 1K8BA 3D2EA 2LY5A 1QQNA 3QFPA 5AQGA 2NY9X 1TI5A 3CQXA 2V7ZA 3KOYA 4GNIA 1T7EA 2ASCA 4KBOA 1I2VA 3LDNA 2KYQA 5FPDA 2K35A 3L4IA 1PTXA 3KOXA 1GPTA 2E8AA 1NGAA 1JZBA 1BA0A 2GL1A 2N2RA 2LJMA 4FL9A 3BK3C 1B3CA 1I2UA 5AQRA 1L4VA 4FSVA 1QQOA 2QWLA 2QWQA 2YIPA 5F2RA 1JKZA 1DQ7A 5FPNA 1NPIA 1LQHA 4HWIA 1JXCA 2M8BB 1NE5A 3PSMA 2A7TA 5AQTA 1WMTA 5FPMA 1PX9A 5BN9A 2MN5A 2QXLA 2LR3A 5AQHA 5EX5A 1BRZA 3QFUA 1GPSA 4H5TA 1I6FA 3C7NB 3GKUA 5AQPA 5AQYA 5AQMA 1JZAA 5BN8A 1NGHA 2ATBA 1T7BA 2E3FA 2MBKA 1BCGA 2KPYA 2SN3A 1KAXA 2KGQA 2KSKA 1CHZA 2YIOA 1XRSB 3GL1A 3R2VA 5CY0A 5AQFA 1C56A 3E7RL 4H5WA 2D56A 1C55A 1NRBA 1NGIA 2QWMA 2QWPA 3D2EB 2N69A 1NGFA 3HSCA 5AQIA 2QWRA 2E2FA 4UAFE 3LDQA 2NY8X 1T0ZA 1BA1A 2E3GA 4HE7A 2QWNA 1CN2A 5AQVA 1HX1A 2LY6A 5AQOA 2GMOA 2KBKA 1VNAA 2B68A 1ZYWA 3KOZA 3KC6A 4UADE 3FZHA 5BPMA 2E0HA 1LQQA 1T1TA 4V1DC 1S3XA 5AQLA 5BPLA 5F0XA 1HJOA 1BK8A 1ZFUA 2N2QA 3GDQA 3M3ZA 2VY6A 3KP0A 3KVGA 2LJ7A 5BPNA 5FPEA 1I6GA 1HPMA 1NH5A 3I33A 1AHOA 5EXWA 4CQKA 1DKGD 3LDOA 3SF4D 5AQZA 4KYPA 3L56A 1POIA 2KHOA 1DJTA 1P0AA 3L6QA 3ATUA
chains in the Genus database with same CATH topology
1NGBA 3FZFA 4H5RA 2QW9A 3D2FB 3KHWA 1KAYA 3A8YA 3FE1A 3IUCA 2JDQD 4IO8A 1ATSA 1NGEA 1YUWA 3FZLA 1NGGA 1QQMA 2BUPA 1KAZA 3FZMA 3ATVA 2QWOA 5AR0A 3LDPA 2LN8A 4UAEF 3JXUA 3LDLA 5AQKA 5AQWA 5AQNA 1NGDA 1NGCA 5AQJA 3C7NA 5AQSA 1NGJA 4H5VA 4H5NA 1BUPA 3FZKA 3CW4A 3AY9A 5AQXA 5EVZA 1ATRA 2E88A 5AQUA 3QMLA 5EY4A 3QI7A 2YILA 5AQQA 3D2EA 1QQNA 3QFPA 5AQGA 2V7ZA 4GNIA 4KBOA 3LDNA 5FPDA 2K35A 3L4IA 2E8AA 1NGAA 1BA0A 4FL9A 3BK3C 5AQRA 4FSVA 1QQOA 2QWLA 2QWQA 2YIPA 5F2RA 5FPNA 4HWIA 5FPMA 5BN9A 2MN5A 2QXLA 5AQHA 5EX5A 3QFUA 4H5TA 3C7NB 5AQYA 5AQPA 5AQMA 5BN8A 1NGHA 2MBKA 2YIOA 3D2FA 5AQTA 1KAXA 5F1XA 3GL1A 3R2VA 5AQFA 4H5WA 2D56A 1NGIA 2QWMA 3D2EB 2QWPA 1NGFA 3HSCA 5AQIA 2QWRA 2E2FA 4UAFE 3LDQA 1BA1A 2QWNA 5AQVA 1HX1A 5AQOA 2GMOA 3KC6A 4UADE 3FZHA 5BPMA 5AQLA 5F0XA 5BPLA 1S3XA 1HJOA 3GDQA 3M3ZA 2VY6A 5FPEA 3KVGA 5BPNA 1HPMA 3I33A 5EXWA 1DKGD 3LDOA 3SF4D 5AQZA 3L56A 1POIA 2KHOA 3CQXA 3L6QA 3ATUA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2LN8 A;  2K35 A; 
#chains in the Genus database with same CATH topology
 1ZYV A;  1ZU3 A;  1NGB A;  3FZF A;  4H5R A;  2LT8 A;  2QW9 A;  3D2F B;  4AEI A;  1P00 A;  1KAY A;  1OZZ A;  3KHW A;  3A8Y A;  1AYJ A;  3KP1 A;  1ZVG A;  3FE1 A;  1ICA A;  3IUC A;  1SEG A;  2JDQ D;  4IO8 A;  2I61 A;  1NRA A;  1PE4 A;  1ATS A;  2YBR C;  1NGE A;  1YUW A;  5KK4 A;  1VNB A;  1WWN A;  3FZL A;  4AB0 A;  1OMY A;  1NGG A;  4UJ0 A;  1ZVE A;  1MYN A;  3E7U X;  1QQM A;  2BUP A;  1KAZ A;  1SN1 A;  3FZM A;  3ATV A;  1KV0 A;  1LQI A;  2BRZ A;  2QWO A;  5AR0 A;  3LDP A;  2B3C A;  1ZUT A;  2LN8 A;  4UAE F;  3JXU A;  2KBJ A;  3LDL A;  5AQK A;  5AQW A;  4AAZ A;  5AQN A;  1NGD A;  2G2K A;  2YEO A;  1T7A A;  1NGC A;  2KJA A;  2MZ0 A;  2LKB A;  3D2F A;  5AQJ A;  1SN4 A;  3C7N A;  5AQS A;  5F1X A;  1NGJ A;  4H5V A;  1FH3 A;  4H5N A;  1BUP A;  2KBH A;  2N66 A;  3FZK A;  1UGL A;  4HHF A;  3AY9 A;  1B7D A;  3CW4 A;  5EVZ A;  1ATR A;  1SNB A;  2LI7 A;  5AQX A;  3KOW A;  2E88 A;  5AQU A;  3QML A;  1WT7 A;  5EY4 A;  3QI7 A;  1N4N A;  1MR4 A;  2YC1 C;  2YIL A;  1BMR A;  5AQQ A;  1K8B A;  3D2E A;  2LY5 A;  1QQN A;  3QFP A;  5AQG A;  2NY9 X;  1TI5 A;  3CQX A;  2V7Z A;  3KOY A;  4GNI A;  1T7E A;  2ASC A;  4KBO A;  1I2V A;  3LDN A;  2KYQ A;  5FPD A;  2K35 A;  3L4I A;  1PTX A;  3KOX A;  1GPT A;  2E8A A;  1NGA A;  1JZB A;  1BA0 A;  2GL1 A;  2N2R A;  2LJM A;  4FL9 A;  3BK3 C;  1B3C A;  1I2U A;  5AQR A;  1L4V A;  4FSV A;  1QQO A;  2QWL A;  2QWQ A;  2YIP A;  5F2R A;  1JKZ A;  1DQ7 A;  5FPN A;  1NPI A;  1LQH A;  4HWI A;  1JXC A;  2M8B B;  1NE5 A;  3PSM A;  2A7T A;  5AQT A;  1WMT A;  5FPM A;  1PX9 A;  5BN9 A;  2MN5 A;  2QXL A;  2LR3 A;  5AQH A;  5EX5 A;  1BRZ A;  3QFU A;  1GPS A;  4H5T A;  1I6F A;  3C7N B;  3GKU A;  5AQP A;  5AQY A;  5AQM A;  1JZA A;  5BN8 A;  1NGH A;  2ATB A;  1T7B A;  2E3F A;  2MBK A;  1BCG A;  2KPY A;  2SN3 A;  1KAX A;  2KGQ A;  2KSK A;  1CHZ A;  2YIO A;  1XRS B;  3GL1 A;  3R2V A;  5CY0 A;  5AQF A;  1C56 A;  3E7R L;  4H5W A;  2D56 A;  1C55 A;  1NRB A;  1NGI A;  2QWM A;  2QWP A;  3D2E B;  2N69 A;  1NGF A;  3HSC A;  5AQI A;  2QWR A;  2E2F A;  4UAF E;  3LDQ A;  2NY8 X;  1T0Z A;  1BA1 A;  2E3G A;  4HE7 A;  2QWN A;  1CN2 A;  5AQV A;  1HX1 A;  2LY6 A;  5AQO A;  2GMO A;  2KBK A;  1VNA A;  2B68 A;  1ZYW A;  3KOZ A;  3KC6 A;  4UAD E;  3FZH A;  5BPM A;  2E0H A;  1LQQ A;  1T1T A;  4V1D C;  1S3X A;  5AQL A;  5BPL A;  5F0X A;  1HJO A;  1BK8 A;  1ZFU A;  2N2Q A;  3GDQ A;  3M3Z A;  2VY6 A;  3KP0 A;  3KVG A;  2LJ7 A;  5BPN A;  5FPE A;  1I6G A;  1HPM A;  1NH5 A;  3I33 A;  1AHO A;  5EXW A;  4CQK A;  1DKG D;  3LDO A;  3SF4 D;  5AQZ A;  4KYP A;  3L56 A;  1POI A;  2KHO A;  1DJT A;  1P0A A;  3L6Q A;  3ATU A; 
#chains in the Genus database with same CATH homology
 1NGB A;  3FZF A;  4H5R A;  2QW9 A;  3D2F B;  3KHW A;  1KAY A;  3A8Y A;  3FE1 A;  3IUC A;  2JDQ D;  4IO8 A;  1ATS A;  1NGE A;  1YUW A;  3FZL A;  1NGG A;  1QQM A;  2BUP A;  1KAZ A;  3FZM A;  3ATV A;  2QWO A;  5AR0 A;  3LDP A;  2LN8 A;  4UAE F;  3JXU A;  3LDL A;  5AQK A;  5AQW A;  5AQN A;  1NGD A;  1NGC A;  5AQJ A;  3C7N A;  5AQS A;  1NGJ A;  4H5V A;  4H5N A;  1BUP A;  3FZK A;  3CW4 A;  3AY9 A;  5AQX A;  5EVZ A;  1ATR A;  2E88 A;  5AQU A;  3QML A;  5EY4 A;  3QI7 A;  2YIL A;  5AQQ A;  3D2E A;  1QQN A;  3QFP A;  5AQG A;  2V7Z A;  4GNI A;  4KBO A;  3LDN A;  5FPD A;  2K35 A;  3L4I A;  2E8A A;  1NGA A;  1BA0 A;  4FL9 A;  3BK3 C;  5AQR A;  4FSV A;  1QQO A;  2QWL A;  2QWQ A;  2YIP A;  5F2R A;  5FPN A;  4HWI A;  5FPM A;  5BN9 A;  2MN5 A;  2QXL A;  5AQH A;  5EX5 A;  3QFU A;  4H5T A;  3C7N B;  5AQY A;  5AQP A;  5AQM A;  5BN8 A;  1NGH A;  2MBK A;  2YIO A;  3D2F A;  5AQT A;  1KAX A;  5F1X A;  3GL1 A;  3R2V A;  5AQF A;  4H5W A;  2D56 A;  1NGI A;  2QWM A;  3D2E B;  2QWP A;  1NGF A;  3HSC A;  5AQI A;  2QWR A;  2E2F A;  4UAF E;  3LDQ A;  1BA1 A;  2QWN A;  5AQV A;  1HX1 A;  5AQO A;  2GMO A;  3KC6 A;  4UAD E;  3FZH A;  5BPM A;  5AQL A;  5F0X A;  5BPL A;  1S3X A;  1HJO A;  3GDQ A;  3M3Z A;  2VY6 A;  5FPE A;  3KVG A;  5BPN A;  1HPM A;  3I33 A;  5EXW A;  1DKG D;  3LDO A;  3SF4 D;  5AQZ A;  3L56 A;  1POI A;  2KHO A;  3CQX A;  3L6Q A;  3ATU A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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