2N2QA

Nmr solution structure of hsafp1
Total Genus 10
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
10
sequence length
54
structure length
54
Chain Sequence
DGVKLCDVPSGTWSGHCGSSSKCSQQCKDREHFAYGGACHYQFPSVKCFCKRQC
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Synergistic Activity of the Plant Defensin HsAFP1 and Caspofungin against Candida albicans Biofilms and Planktonic Cultures.
pubmed doi rcsb
molecule tags Antifungal protein
source organism Heuchera sanguinea
molecule keywords Defensin-like protein 1
total genus 10
structure length 54
sequence length 54
ec nomenclature
pdb deposition date 2015-05-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00304 Gamma-thionin Gamma-thionin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.30.10 Alpha Beta 2-Layer Sandwich Defensin A-like Knottin, scorpion toxin-like 2n2qA00
2N69A 1WT7A 1CN2A 1KV0A 4UJ0A 1T1TA 2I61A 1N4NA 1ZYWA 2LT8A 1NRAA 1OMYA 1P00A 1MR4A 1I6FA 1NH5A 1PE4A 2LKBA 2N2RA 2LR3A 4AB0A 3E7RL 3E7UX 1TI5A 3PSMA 1CHZA 1SN1A 2LY5A 1OZZA 1ZVEA 1VNBA 4V1DC 2E0HA 1JKZA 1I2VA 2BRZA 1NE5A 1JZBA 1PX9A 1ICAA 1T0ZA 1ZYVA 1BCGA 1BRZA 2LY6A 2SN3A 2LJMA 1LQQA 1BK8A 1LQIA 1NPIA 1GPTA 1T7EA 1B3CA 1C55A 2E3GA 1FH3A 1AHOA 1B7DA 2B3CA 5CY0A 1LQHA 2GL1A 1ZVGA 1ZU3A 2NY9X 2NY8X 1SNBA 1GPSA 2ASCA 2KSKA 2KGQA 1JXCA 2E3FA 4CQKA 2M8BB 2KBKA 4KYPA 1C56A 1P0AA 1I2UA 2KBJA 2YEOA 1ZUTA 1WWNA 2LJ7A 1ZFUA 5KK4A 1T7AA 2ATBA 1I6GA 1VNAA 2KBHA 1JZAA 1BMRA 2A7TA 4HHFA 2YBRC 4AAZA 1SEGA 4AEIA 1DJTA 2KJAA 1AYJA 1DQ7A 2B68A 2LI7A 1WMTA 4HE7A 1MYNA 2N66A 1SN4A 1T7BA 1PTXA 2KPYA 1NRBA 2YC1C 2MZ0A 2N2QA 2KYQA 1L4VA
chains in the Genus database with same CATH superfamily
2YILA 2N69A 1WT7A 4FSVA 1KV0A 5AQNA 5AQJA 4UJ0A 1CN2A 3GDQA 5AQVA 1T1TA 2I61A 1N4NA 4H5TA 1ZYWA 2E2FA 5AR0A 2LT8A 1NRAA 5BPMA 4FL9A 1BA1A 1OMYA 5F1XA 2QWNA 1KAXA 1P00A 1XRSB 4IO8A 1MR4A 3HSCA 1I6FA 1HPMA 1NH5A 1PE4A 5FPEA 2LKBA 2N2RA 5AQLA 2LR3A 3C7NB 2LN8A 3FE1A 4AB0A 1BA0A 2QWOA 5FPMA 3E7RL 3E7UX 5BN8A 3AY9A 3CW4A 1TI5A 1QQNA 1BUPA 3PSMA 1CHZA 1SN1A 2VY6A 2LY5A 1OZZA 1ZVEA 2YIOA 5AQFA 2QWPA 1VNBA 4V1DC 3QMLA 5AQPA 2E0HA 1YUWA 2QWMA 1JKZA 1POIA 3L6QA 2E88A 4UAFE 3KHWA 1NGHA 3KC6A 3L4IA 4GNIA 4H5WA 5AQXA 5F2RA 1I2VA 2QW9A 2BRZA 1NE5A 2KHOA 1JZBA 1PX9A 4UAEF 1ICAA 2V7ZA 5AQOA 1HJOA 1T0ZA 3CQXA 1QQMA 1ZYVA 5AQHA 3GKUA 3FZFA 3BK3C 3QI7A 1BCGA 5EXWA 2JDQD 2LY6A 1BRZA 3KP1A 1K8BA 5AQUA 5F0XA 3IUCA 2SN3A 2E8AA 2QXLA 2LJMA 1LQQA 1QQOA 2QWQA 1LQIA 3LDLA 3SF4D 1BK8A 1S3XA 5AQQA 1ATRA 1NPIA 1GPTA 1T7EA 1B3CA 3FZHA 3FZLA 1NGAA 3QFUA 5AQMA 1C55A 2QWRA 1NGCA 2K35A 2E3GA 1FH3A 1AHOA 3KOXA 1HX1A 1B7DA 2B3CA 5CY0A 1LQHA 2GL1A 1ZVGA 1ZU3A 4KBOA 5EVZA 5BN9A 3FZKA 2NY9X 2NY8X 3KOYA 1SNBA 1GPSA 2ASCA 2KSKA 2KGQA 3LDOA 3KOZA 1NGBA 5AQGA 3KOWA 1JXCA 2E3FA 2MBKA 4CQKA 1NGJA 2M8BB 5AQRA 1NGEA 2KBKA 5AQZA 5BPLA 4KYPA 1C56A 1P0AA 3FZMA 4H5NA 1I2UA 1KAZA 2KBJA 2YEOA 2YIPA 1ZUTA 1WWNA 2LJ7A 4HWIA 5EX5A 1ZFUA 5KK4A 1T7AA 2ATBA 2MN5A 3LDPA 3R2VA 1I6GA 3LDQA 3C7NA 1VNAA 2KBHA 1JZAA 1DKGD 1BMRA 2A7TA 5AQIA 1KAYA 3D2EB 4HHFA 1ATSA 5AQSA 2YBRC 1UGLA 3D2FB 5FPNA 2QWLA 4UADE 4AAZA 1SEGA 5AQWA 1DJTA 2KJAA 4AEIA 1DQ7A 1AYJA 3KVGA 2B68A 5AQTA 2G2KA 2LI7A 1WMTA 4HE7A 1MYNA 2N66A 1NGFA 3KP0A 1SN4A 1NGDA 1PTXA 1T7BA 2KPYA 3ATVA 3I33A 3JXUA 3LDNA 4H5RA 1NRBA 2BUPA 2YC1C 1NGIA 2MZ0A 2N2QA 3D2EA 3A8YA 3L56A 3D2FA 3M3ZA 3QFPA 5FPDA 5AQKA 5EY4A 2KYQA 1L4VA 2D56A 5BPNA 2GMOA 5AQYA 3GL1A 3ATUA 4H5VA 1NGGA
chains in the Genus database with same CATH topology
2N69A 1WT7A 1CN2A 1KV0A 4UJ0A 1T1TA 2I61A 1N4NA 1ZYWA 2LT8A 1NRAA 1OMYA 1P00A 1MR4A 1I6FA 1NH5A 1PE4A 2LKBA 2N2RA 2LR3A 4AB0A 3E7RL 3E7UX 1TI5A 3PSMA 1CHZA 1SN1A 2LY5A 1OZZA 1ZVEA 1VNBA 4V1DC 2E0HA 1JKZA 1I2VA 2BRZA 1NE5A 1JZBA 1PX9A 1ICAA 1T0ZA 1ZYVA 1BCGA 1BRZA 2LY6A 2SN3A 2LJMA 1LQQA 1BK8A 1LQIA 1NPIA 1GPTA 1T7EA 1B3CA 1C55A 2E3GA 1FH3A 1AHOA 1B7DA 2B3CA 5CY0A 1LQHA 2GL1A 1ZVGA 1ZU3A 2NY9X 2NY8X 1SNBA 1GPSA 2ASCA 2KSKA 2KGQA 1JXCA 2E3FA 4CQKA 2M8BB 2KBKA 4KYPA 1C56A 1P0AA 1I2UA 2KBJA 2YEOA 1ZUTA 1WWNA 2LJ7A 1ZFUA 5KK4A 1T7AA 2ATBA 1I6GA 1VNAA 2KBHA 1JZAA 1BMRA 2A7TA 4HHFA 2YBRC 4AAZA 1SEGA 4AEIA 1DJTA 2KJAA 1AYJA 1DQ7A 2B68A 2LI7A 1WMTA 4HE7A 1MYNA 2N66A 1SN4A 1T7BA 1PTXA 2KPYA 1NRBA 2YC1C 2MZ0A 2N2QA 2KYQA 1L4VA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2N69 A;  1WT7 A;  1CN2 A;  1KV0 A;  4UJ0 A;  1T1T A;  2I61 A;  1N4N A;  1ZYW A;  2LT8 A;  1NRA A;  1OMY A;  1P00 A;  1MR4 A;  1I6F A;  1NH5 A;  1PE4 A;  2LKB A;  2N2R A;  2LR3 A;  4AB0 A;  3E7R L;  3E7U X;  1TI5 A;  3PSM A;  1CHZ A;  1SN1 A;  2LY5 A;  1OZZ A;  1ZVE A;  1VNB A;  4V1D C;  2E0H A;  1JKZ A;  1I2V A;  2BRZ A;  1NE5 A;  1JZB A;  1PX9 A;  1ICA A;  1T0Z A;  1ZYV A;  1BCG A;  1BRZ A;  2LY6 A;  2SN3 A;  2LJM A;  1LQQ A;  1BK8 A;  1LQI A;  1NPI A;  1GPT A;  1T7E A;  1B3C A;  1C55 A;  2E3G A;  1FH3 A;  1AHO A;  1B7D A;  2B3C A;  5CY0 A;  1LQH A;  2GL1 A;  1ZVG A;  1ZU3 A;  2NY9 X;  2NY8 X;  1SNB A;  1GPS A;  2ASC A;  2KSK A;  2KGQ A;  1JXC A;  2E3F A;  4CQK A;  2M8B B;  2KBK A;  4KYP A;  1C56 A;  1P0A A;  1I2U A;  2KBJ A;  2YEO A;  1ZUT A;  1WWN A;  2LJ7 A;  1ZFU A;  5KK4 A;  1T7A A;  2ATB A;  1I6G A;  1VNA A;  2KBH A;  1JZA A;  1BMR A;  2A7T A;  4HHF A;  2YBR C;  4AAZ A;  1SEG A;  4AEI A;  1DJT A;  2KJA A;  1AYJ A;  1DQ7 A;  2B68 A;  2LI7 A;  1WMT A;  4HE7 A;  1MYN A;  2N66 A;  1SN4 A;  1T7B A;  1PTX A;  2KPY A;  1NRB A;  2YC1 C;  2MZ0 A;  2N2Q A;  2KYQ A;  1L4V A; 
#chains in the Genus database with same CATH topology
 2YIL A;  2N69 A;  1WT7 A;  4FSV A;  1KV0 A;  5AQN A;  5AQJ A;  4UJ0 A;  1CN2 A;  3GDQ A;  5AQV A;  1T1T A;  2I61 A;  1N4N A;  4H5T A;  1ZYW A;  2E2F A;  5AR0 A;  2LT8 A;  1NRA A;  5BPM A;  4FL9 A;  1BA1 A;  1OMY A;  5F1X A;  2QWN A;  1KAX A;  1P00 A;  1XRS B;  4IO8 A;  1MR4 A;  3HSC A;  1I6F A;  1HPM A;  1NH5 A;  1PE4 A;  5FPE A;  2LKB A;  2N2R A;  5AQL A;  2LR3 A;  3C7N B;  2LN8 A;  3FE1 A;  4AB0 A;  1BA0 A;  2QWO A;  5FPM A;  3E7R L;  3E7U X;  5BN8 A;  3AY9 A;  3CW4 A;  1TI5 A;  1QQN A;  1BUP A;  3PSM A;  1CHZ A;  1SN1 A;  2VY6 A;  2LY5 A;  1OZZ A;  1ZVE A;  2YIO A;  5AQF A;  2QWP A;  1VNB A;  4V1D C;  3QML A;  5AQP A;  2E0H A;  1YUW A;  2QWM A;  1JKZ A;  1POI A;  3L6Q A;  2E88 A;  4UAF E;  3KHW A;  1NGH A;  3KC6 A;  3L4I A;  4GNI A;  4H5W A;  5AQX A;  5F2R A;  1I2V A;  2QW9 A;  2BRZ A;  1NE5 A;  2KHO A;  1JZB A;  1PX9 A;  4UAE F;  1ICA A;  2V7Z A;  5AQO A;  1HJO A;  1T0Z A;  3CQX A;  1QQM A;  1ZYV A;  5AQH A;  3GKU A;  3FZF A;  3BK3 C;  3QI7 A;  1BCG A;  5EXW A;  2JDQ D;  2LY6 A;  1BRZ A;  3KP1 A;  1K8B A;  5AQU A;  5F0X A;  3IUC A;  2SN3 A;  2E8A A;  2QXL A;  2LJM A;  1LQQ A;  1QQO A;  2QWQ A;  1LQI A;  3LDL A;  3SF4 D;  1BK8 A;  1S3X A;  5AQQ A;  1ATR A;  1NPI A;  1GPT A;  1T7E A;  1B3C A;  3FZH A;  3FZL A;  1NGA A;  3QFU A;  5AQM A;  1C55 A;  2QWR A;  1NGC A;  2K35 A;  2E3G A;  1FH3 A;  1AHO A;  3KOX A;  1HX1 A;  1B7D A;  2B3C A;  5CY0 A;  1LQH A;  2GL1 A;  1ZVG A;  1ZU3 A;  4KBO A;  5EVZ A;  5BN9 A;  3FZK A;  2NY9 X;  2NY8 X;  3KOY A;  1SNB A;  1GPS A;  2ASC A;  2KSK A;  2KGQ A;  3LDO A;  3KOZ A;  1NGB A;  5AQG A;  3KOW A;  1JXC A;  2E3F A;  2MBK A;  4CQK A;  1NGJ A;  2M8B B;  5AQR A;  1NGE A;  2KBK A;  5AQZ A;  5BPL A;  4KYP A;  1C56 A;  1P0A A;  3FZM A;  4H5N A;  1I2U A;  1KAZ A;  2KBJ A;  2YEO A;  2YIP A;  1ZUT A;  1WWN A;  2LJ7 A;  4HWI A;  5EX5 A;  1ZFU A;  5KK4 A;  1T7A A;  2ATB A;  2MN5 A;  3LDP A;  3R2V A;  1I6G A;  3LDQ A;  3C7N A;  1VNA A;  2KBH A;  1JZA A;  1DKG D;  1BMR A;  2A7T A;  5AQI A;  1KAY A;  3D2E B;  4HHF A;  1ATS A;  5AQS A;  2YBR C;  1UGL A;  3D2F B;  5FPN A;  2QWL A;  4UAD E;  4AAZ A;  1SEG A;  5AQW A;  1DJT A;  2KJA A;  4AEI A;  1DQ7 A;  1AYJ A;  3KVG A;  2B68 A;  5AQT A;  2G2K A;  2LI7 A;  1WMT A;  4HE7 A;  1MYN A;  2N66 A;  1NGF A;  3KP0 A;  1SN4 A;  1NGD A;  1PTX A;  1T7B A;  2KPY A;  3ATV A;  3I33 A;  3JXU A;  3LDN A;  4H5R A;  1NRB A;  2BUP A;  2YC1 C;  1NGI A;  2MZ0 A;  2N2Q A;  3D2E A;  3A8Y A;  3L56 A;  3D2F A;  3M3Z A;  3QFP A;  5FPD A;  5AQK A;  5EY4 A;  2KYQ A;  1L4V A;  2D56 A;  5BPN A;  2GMO A;  5AQY A;  3GL1 A;  3ATU A;  4H5V A;  1NGG A; 
#chains in the Genus database with same CATH homology
 2N69 A;  1WT7 A;  1CN2 A;  1KV0 A;  4UJ0 A;  1T1T A;  2I61 A;  1N4N A;  1ZYW A;  2LT8 A;  1NRA A;  1OMY A;  1P00 A;  1MR4 A;  1I6F A;  1NH5 A;  1PE4 A;  2LKB A;  2N2R A;  2LR3 A;  4AB0 A;  3E7R L;  3E7U X;  1TI5 A;  3PSM A;  1CHZ A;  1SN1 A;  2LY5 A;  1OZZ A;  1ZVE A;  1VNB A;  4V1D C;  2E0H A;  1JKZ A;  1I2V A;  2BRZ A;  1NE5 A;  1JZB A;  1PX9 A;  1ICA A;  1T0Z A;  1ZYV A;  1BCG A;  1BRZ A;  2LY6 A;  2SN3 A;  2LJM A;  1LQQ A;  1BK8 A;  1LQI A;  1NPI A;  1GPT A;  1T7E A;  1B3C A;  1C55 A;  2E3G A;  1FH3 A;  1AHO A;  1B7D A;  2B3C A;  5CY0 A;  1LQH A;  2GL1 A;  1ZVG A;  1ZU3 A;  2NY9 X;  2NY8 X;  1SNB A;  1GPS A;  2ASC A;  2KSK A;  2KGQ A;  1JXC A;  2E3F A;  4CQK A;  2M8B B;  2KBK A;  4KYP A;  1C56 A;  1P0A A;  1I2U A;  2KBJ A;  2YEO A;  1ZUT A;  1WWN A;  2LJ7 A;  1ZFU A;  5KK4 A;  1T7A A;  2ATB A;  1I6G A;  1VNA A;  2KBH A;  1JZA A;  1BMR A;  2A7T A;  4HHF A;  2YBR C;  4AAZ A;  1SEG A;  4AEI A;  1DJT A;  2KJA A;  1AYJ A;  1DQ7 A;  2B68 A;  2LI7 A;  1WMT A;  4HE7 A;  1MYN A;  2N66 A;  1SN4 A;  1T7B A;  1PTX A;  2KPY A;  1NRB A;  2YC1 C;  2MZ0 A;  2N2Q A;  2KYQ A;  1L4V A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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