2NY8X

Nmr structure of antibacterial defensin def-aaa from the insect anopheles gambiae
Total Genus 5
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
5
sequence length
40
structure length
40
Chain Sequence
ATCDLASGFGVGSSLCAAHCIARRYRGGYCNSKAVCVCRN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Rational design of peptides active against the gram positive bacteria Staphylococcus aureus
pubmed doi rcsb
molecule tags Antimicrobial protein
source organism Anopheles gambiae
molecule keywords defensin
total genus 5
structure length 40
sequence length 40
ec nomenclature
pdb deposition date 2006-11-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
X PF01097 Defensin_2 Arthropod defensin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.30.10 Alpha Beta 2-Layer Sandwich Defensin A-like Knottin, scorpion toxin-like 2ny8X00
2N2QA 1B7DA 1C55A 1NRAA 2SN3A 1AYJA 2B3CA 1OMYA 1VNBA 1I6GA 1NE5A 1P0AA 1ZYWA 1AHOA 1MYNA 1N4NA 1P00A 1T7EA 1T0ZA 2KSKA 1ZUTA 1DQ7A 4CQKA 1WT7A 1JZBA 1C56A 1WMTA 3PSMA 4V1DC 3E7RL 1ZVGA 2ATBA 2LJ7A 2N69A 2NY8X 1ZU3A 2KBHA 1OZZA 1T7AA 1NPIA 1WWNA 1GPTA 1ZYVA 1FH3A 2YBRC 1SN4A 1LQQA 4HE7A 2KBJA 1PTXA 1T1TA 1MR4A 2M8BB 1T7BA 1PE4A 2LY5A 2ASCA 1ZVEA 2YEOA 2KJAA 1LQIA 1BMRA 2E0HA 1L4VA 1SEGA 4KYPA 1I2UA 4AAZA 1JZAA 2LR3A 2B68A 4HHFA 1B3CA 2LT8A 2A7TA 1PX9A 1I2VA 2KBKA 2MZ0A 2E3GA 1CHZA 2BRZA 1NRBA 4AEIA 2KGQA 4UJ0A 1BCGA 1JXCA 1BRZA 2I61A 2NY9X 1NH5A 1KV0A 1TI5A 1BK8A 1VNAA 2LY6A 2LJMA 1DJTA 5KK4A 1JKZA 2N66A 1GPSA 2N2RA 2YC1C 5CY0A 3E7UX 2GL1A 1ICAA 2LKBA 1SN1A 1SNBA 1CN2A 4AB0A 1ZFUA 1I6FA 2LI7A 2E3FA 2KYQA 1LQHA 2KPYA
chains in the Genus database with same CATH superfamily
2N2QA 1B7DA 5BPNA 2KHOA 3QFUA 1K8BA 1C55A 1NRAA 2SN3A 4H5RA 3KP1A 2B3CA 1AYJA 4UADE 4HWIA 3JXUA 1OMYA 1VNBA 3KOXA 1I6GA 4GNIA 1NGIA 1NE5A 4KBOA 5FPEA 1HPMA 3D2FA 1P0AA 1YUWA 3L56A 1ZYWA 1AHOA 5AQWA 2QW9A 3ATVA 3FZMA 3KOYA 1MYNA 1NGDA 1N4NA 1P00A 3GDQA 3SF4D 1T7EA 2D56A 5AQVA 3QI7A 1T0ZA 2KSKA 1KAZA 2K35A 1ZUTA 3D2FB 5AQHA 1KAXA 3D2EA 3FE1A 3LDQA 5AQJA 1DQ7A 2YIOA 4CQKA 4H5NA 2QWMA 1WT7A 3ATUA 1JZBA 5AQOA 1C56A 1KAYA 1WMTA 1NGFA 3CW4A 3D2EB 1S3XA 3PSMA 3BK3C 4V1DC 3E7RL 4FSVA 2E2FA 1ZVGA 5AQMA 1NGJA 2ATBA 1ATSA 5BPLA 2LJ7A 2N69A 5F2RA 5BPMA 2NY8X 5AQYA 1ZU3A 5EY4A 2KBHA 3KVGA 1NGAA 1OZZA 2MBKA 1T7AA 1NPIA 1WWNA 3LDOA 5AQXA 1GPTA 1ZYVA 3QMLA 2YBRC 1FH3A 3CQXA 3KOWA 4H5WA 1SN4A 4UAEF 5AQZA 1LQQA 1NGEA 4HE7A 2KBJA 2QWQA 1PTXA 2V7ZA 1T1TA 5AQPA 1MR4A 2M8BB 1T7BA 1PE4A 2LY5A 2ASCA 2QWLA 2QWRA 3FZHA 3KHWA 5AR0A 1ATRA 2E8AA 1ZVEA 2QWNA 3HSCA 2YEOA 5BN8A 3M3ZA 5FPMA 5EXWA 2KJAA 1LQIA 1BMRA 2E0HA 1L4VA 1BA0A 1SEGA 2BUPA 4KYPA 5FPDA 3L4IA 4AAZA 1I2UA 4FL9A 1HJOA 1JZAA 3GKUA 5AQIA 1DKGD 2YILA 2B68A 2LR3A 5AQSA 4HHFA 1NGGA 2LT8A 5AQQA 1BUPA 1BA1A 2A7TA 5F1XA 3LDPA 1B3CA 1QQNA 5AQRA 3AY9A 1PX9A 2MN5A 2JDQD 2E88A 1I2VA 2KBKA 2MZ0A 2E3GA 1CHZA 3IUCA 2BRZA 1XRSB 5AQGA 5BN9A 1NGBA 5AQLA 1NRBA 4AEIA 2KGQA 5AQTA 1QQMA 2G2KA 2LN8A 3C7NB 3I33A 1QQOA 4UJ0A 1BCGA 1JXCA 3FZFA 1BRZA 2VY6A 3KC6A 2QWPA 3R2VA 2I61A 3FZKA 2NY9X 4IO8A 1NH5A 1KV0A 1TI5A 1BK8A 1VNAA 2LY6A 2QWOA 2LJMA 2GMOA 1DJTA 5KK4A 1JKZA 2N66A 1GPSA 2N2RA 1UGLA 5AQNA 1NGHA 3FZLA 2YC1C 3L6QA 5AQKA 5CY0A 3E7UX 5FPNA 5F0XA 5AQFA 3LDLA 2GL1A 3QFPA 1ICAA 2LKBA 1SN1A 1SNBA 3C7NA 2YIPA 1POIA 1CN2A 4AB0A 1ZFUA 1I6FA 3A8YA 5AQUA 1HX1A 2QXLA 2LI7A 2E3FA 5EX5A 1NGCA 3LDNA 2KYQA 4H5VA 1LQHA 3KOZA 2KPYA 5EVZA 4UAFE 3GL1A 4H5TA 3KP0A
chains in the Genus database with same CATH topology
2N2QA 1B7DA 1C55A 1NRAA 2SN3A 1AYJA 2B3CA 1OMYA 1VNBA 1I6GA 1NE5A 1P0AA 1ZYWA 1AHOA 1MYNA 1N4NA 1P00A 1T7EA 1T0ZA 2KSKA 1ZUTA 1DQ7A 4CQKA 1WT7A 1JZBA 1C56A 1WMTA 3PSMA 4V1DC 3E7RL 1ZVGA 2ATBA 2LJ7A 2N69A 2NY8X 1ZU3A 2KBHA 1OZZA 1T7AA 1NPIA 1WWNA 1GPTA 1ZYVA 1FH3A 2YBRC 1SN4A 1LQQA 4HE7A 2KBJA 1PTXA 1T1TA 1MR4A 2M8BB 1T7BA 1PE4A 2LY5A 2ASCA 1ZVEA 2YEOA 2KJAA 1LQIA 1BMRA 2E0HA 1L4VA 1SEGA 4KYPA 1I2UA 4AAZA 1JZAA 2LR3A 2B68A 4HHFA 1B3CA 2LT8A 2A7TA 1PX9A 1I2VA 2KBKA 2MZ0A 2E3GA 1CHZA 2BRZA 1NRBA 4AEIA 2KGQA 4UJ0A 1BCGA 1JXCA 1BRZA 2I61A 2NY9X 1NH5A 1KV0A 1TI5A 1BK8A 1VNAA 2LY6A 2LJMA 1DJTA 5KK4A 1JKZA 2N66A 1GPSA 2N2RA 2YC1C 5CY0A 3E7UX 2GL1A 1ICAA 2LKBA 1SN1A 1SNBA 1CN2A 4AB0A 1ZFUA 1I6FA 2LI7A 2E3FA 2KYQA 1LQHA 2KPYA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2N2Q A;  1B7D A;  1C55 A;  1NRA A;  2SN3 A;  1AYJ A;  2B3C A;  1OMY A;  1VNB A;  1I6G A;  1NE5 A;  1P0A A;  1ZYW A;  1AHO A;  1MYN A;  1N4N A;  1P00 A;  1T7E A;  1T0Z A;  2KSK A;  1ZUT A;  1DQ7 A;  4CQK A;  1WT7 A;  1JZB A;  1C56 A;  1WMT A;  3PSM A;  4V1D C;  3E7R L;  1ZVG A;  2ATB A;  2LJ7 A;  2N69 A;  2NY8 X;  1ZU3 A;  2KBH A;  1OZZ A;  1T7A A;  1NPI A;  1WWN A;  1GPT A;  1ZYV A;  1FH3 A;  2YBR C;  1SN4 A;  1LQQ A;  4HE7 A;  2KBJ A;  1PTX A;  1T1T A;  1MR4 A;  2M8B B;  1T7B A;  1PE4 A;  2LY5 A;  2ASC A;  1ZVE A;  2YEO A;  2KJA A;  1LQI A;  1BMR A;  2E0H A;  1L4V A;  1SEG A;  4KYP A;  1I2U A;  4AAZ A;  1JZA A;  2LR3 A;  2B68 A;  4HHF A;  1B3C A;  2LT8 A;  2A7T A;  1PX9 A;  1I2V A;  2KBK A;  2MZ0 A;  2E3G A;  1CHZ A;  2BRZ A;  1NRB A;  4AEI A;  2KGQ A;  4UJ0 A;  1BCG A;  1JXC A;  1BRZ A;  2I61 A;  2NY9 X;  1NH5 A;  1KV0 A;  1TI5 A;  1BK8 A;  1VNA A;  2LY6 A;  2LJM A;  1DJT A;  5KK4 A;  1JKZ A;  2N66 A;  1GPS A;  2N2R A;  2YC1 C;  5CY0 A;  3E7U X;  2GL1 A;  1ICA A;  2LKB A;  1SN1 A;  1SNB A;  1CN2 A;  4AB0 A;  1ZFU A;  1I6F A;  2LI7 A;  2E3F A;  2KYQ A;  1LQH A;  2KPY A; 
#chains in the Genus database with same CATH topology
 2N2Q A;  1B7D A;  5BPN A;  2KHO A;  3QFU A;  1K8B A;  1C55 A;  1NRA A;  2SN3 A;  4H5R A;  3KP1 A;  2B3C A;  1AYJ A;  4UAD E;  4HWI A;  3JXU A;  1OMY A;  1VNB A;  3KOX A;  1I6G A;  4GNI A;  1NGI A;  1NE5 A;  4KBO A;  5FPE A;  1HPM A;  3D2F A;  1P0A A;  1YUW A;  3L56 A;  1ZYW A;  1AHO A;  5AQW A;  2QW9 A;  3ATV A;  3FZM A;  3KOY A;  1MYN A;  1NGD A;  1N4N A;  1P00 A;  3GDQ A;  3SF4 D;  1T7E A;  2D56 A;  5AQV A;  3QI7 A;  1T0Z A;  2KSK A;  1KAZ A;  2K35 A;  1ZUT A;  3D2F B;  5AQH A;  1KAX A;  3D2E A;  3FE1 A;  3LDQ A;  5AQJ A;  1DQ7 A;  2YIO A;  4CQK A;  4H5N A;  2QWM A;  1WT7 A;  3ATU A;  1JZB A;  5AQO A;  1C56 A;  1KAY A;  1WMT A;  1NGF A;  3CW4 A;  3D2E B;  1S3X A;  3PSM A;  3BK3 C;  4V1D C;  3E7R L;  4FSV A;  2E2F A;  1ZVG A;  5AQM A;  1NGJ A;  2ATB A;  1ATS A;  5BPL A;  2LJ7 A;  2N69 A;  5F2R A;  5BPM A;  2NY8 X;  5AQY A;  1ZU3 A;  5EY4 A;  2KBH A;  3KVG A;  1NGA A;  1OZZ A;  2MBK A;  1T7A A;  1NPI A;  1WWN A;  3LDO A;  5AQX A;  1GPT A;  1ZYV A;  3QML A;  2YBR C;  1FH3 A;  3CQX A;  3KOW A;  4H5W A;  1SN4 A;  4UAE F;  5AQZ A;  1LQQ A;  1NGE A;  4HE7 A;  2KBJ A;  2QWQ A;  1PTX A;  2V7Z A;  1T1T A;  5AQP A;  1MR4 A;  2M8B B;  1T7B A;  1PE4 A;  2LY5 A;  2ASC A;  2QWL A;  2QWR A;  3FZH A;  3KHW A;  5AR0 A;  1ATR A;  2E8A A;  1ZVE A;  2QWN A;  3HSC A;  2YEO A;  5BN8 A;  3M3Z A;  5FPM A;  5EXW A;  2KJA A;  1LQI A;  1BMR A;  2E0H A;  1L4V A;  1BA0 A;  1SEG A;  2BUP A;  4KYP A;  5FPD A;  3L4I A;  4AAZ A;  1I2U A;  4FL9 A;  1HJO A;  1JZA A;  3GKU A;  5AQI A;  1DKG D;  2YIL A;  2B68 A;  2LR3 A;  5AQS A;  4HHF A;  1NGG A;  2LT8 A;  5AQQ A;  1BUP A;  1BA1 A;  2A7T A;  5F1X A;  3LDP A;  1B3C A;  1QQN A;  5AQR A;  3AY9 A;  1PX9 A;  2MN5 A;  2JDQ D;  2E88 A;  1I2V A;  2KBK A;  2MZ0 A;  2E3G A;  1CHZ A;  3IUC A;  2BRZ A;  1XRS B;  5AQG A;  5BN9 A;  1NGB A;  5AQL A;  1NRB A;  4AEI A;  2KGQ A;  5AQT A;  1QQM A;  2G2K A;  2LN8 A;  3C7N B;  3I33 A;  1QQO A;  4UJ0 A;  1BCG A;  1JXC A;  3FZF A;  1BRZ A;  2VY6 A;  3KC6 A;  2QWP A;  3R2V A;  2I61 A;  3FZK A;  2NY9 X;  4IO8 A;  1NH5 A;  1KV0 A;  1TI5 A;  1BK8 A;  1VNA A;  2LY6 A;  2QWO A;  2LJM A;  2GMO A;  1DJT A;  5KK4 A;  1JKZ A;  2N66 A;  1GPS A;  2N2R A;  1UGL A;  5AQN A;  1NGH A;  3FZL A;  2YC1 C;  3L6Q A;  5AQK A;  5CY0 A;  3E7U X;  5FPN A;  5F0X A;  5AQF A;  3LDL A;  2GL1 A;  3QFP A;  1ICA A;  2LKB A;  1SN1 A;  1SNB A;  3C7N A;  2YIP A;  1POI A;  1CN2 A;  4AB0 A;  1ZFU A;  1I6F A;  3A8Y A;  5AQU A;  1HX1 A;  2QXL A;  2LI7 A;  2E3F A;  5EX5 A;  1NGC A;  3LDN A;  2KYQ A;  4H5V A;  1LQH A;  3KOZ A;  2KPY A;  5EVZ A;  4UAF E;  3GL1 A;  4H5T A;  3KP0 A; 
#chains in the Genus database with same CATH homology
 2N2Q A;  1B7D A;  1C55 A;  1NRA A;  2SN3 A;  1AYJ A;  2B3C A;  1OMY A;  1VNB A;  1I6G A;  1NE5 A;  1P0A A;  1ZYW A;  1AHO A;  1MYN A;  1N4N A;  1P00 A;  1T7E A;  1T0Z A;  2KSK A;  1ZUT A;  1DQ7 A;  4CQK A;  1WT7 A;  1JZB A;  1C56 A;  1WMT A;  3PSM A;  4V1D C;  3E7R L;  1ZVG A;  2ATB A;  2LJ7 A;  2N69 A;  2NY8 X;  1ZU3 A;  2KBH A;  1OZZ A;  1T7A A;  1NPI A;  1WWN A;  1GPT A;  1ZYV A;  1FH3 A;  2YBR C;  1SN4 A;  1LQQ A;  4HE7 A;  2KBJ A;  1PTX A;  1T1T A;  1MR4 A;  2M8B B;  1T7B A;  1PE4 A;  2LY5 A;  2ASC A;  1ZVE A;  2YEO A;  2KJA A;  1LQI A;  1BMR A;  2E0H A;  1L4V A;  1SEG A;  4KYP A;  1I2U A;  4AAZ A;  1JZA A;  2LR3 A;  2B68 A;  4HHF A;  1B3C A;  2LT8 A;  2A7T A;  1PX9 A;  1I2V A;  2KBK A;  2MZ0 A;  2E3G A;  1CHZ A;  2BRZ A;  1NRB A;  4AEI A;  2KGQ A;  4UJ0 A;  1BCG A;  1JXC A;  1BRZ A;  2I61 A;  2NY9 X;  1NH5 A;  1KV0 A;  1TI5 A;  1BK8 A;  1VNA A;  2LY6 A;  2LJM A;  1DJT A;  5KK4 A;  1JKZ A;  2N66 A;  1GPS A;  2N2R A;  2YC1 C;  5CY0 A;  3E7U X;  2GL1 A;  1ICA A;  2LKB A;  1SN1 A;  1SNB A;  1CN2 A;  4AB0 A;  1ZFU A;  1I6F A;  2LI7 A;  2E3F A;  2KYQ A;  1LQH A;  2KPY A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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