2YBRC

Crystal structure of the human derived single chain antibody fragment (scfv) 9004g in complex with cn2 toxin from the scorpion centruroides noxius hoffmann
Total Genus 15
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
15
sequence length
65
structure length
65
Chain Sequence
KEGYLVDKNTGCKYECLKLGDNDYCLRECKQQYGKGAGGYCYAFACWCTHLYEQAIVWPLPNKRC
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Basis of Neutralization of the Major Toxic Component from the Scorpion Centruroides Noxius Hoffmann by a Human-Derived Single Chain Antibody Fragment
pubmed doi rcsb
molecule tags Immune system/toxin
source organism Homo sapiens
molecule keywords SINGLE CHAIN ANTIBODY FRAGMENT 9004G
total genus 15
structure length 65
sequence length 65
chains with identical sequence F, I
ec nomenclature
pdb deposition date 2011-03-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF00537 Toxin_3 Scorpion toxin-like domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.30.10 Alpha Beta 2-Layer Sandwich Defensin A-like Knottin, scorpion toxin-like 2ybrC00
4UJ0A 2SN3A 2N2QA 2LKBA 2LR3A 1P0AA 1ZFUA 1BCGA 3E7UX 1TI5A 1ZVGA 1WMTA 4KYPA 1ZVEA 1ZYWA 2B3CA 1AYJA 3PSMA 5CY0A 1B3CA 4V1DC 2LY5A 2E3GA 2LJ7A 1C56A 1VNBA 2ATBA 1LQIA 1JZAA 2YEOA 4AAZA 2KYQA 1JKZA 1NE5A 1MR4A 1P00A 2M8BB 2KPYA 1NRAA 1ZYVA 1SNBA 2NY9X 1NH5A 1T7EA 1DQ7A 1ZU3A 1MYNA 1VNAA 2KJAA 2ASCA 2NY8X 1I2VA 2YC1C 1AHOA 1I2UA 2E0HA 2A7TA 1SN4A 1GPTA 1NPIA 4HE7A 1T7BA 1L4VA 2YBRC 1WWNA 2N69A 1PX9A 2BRZA 2B68A 2KBHA 3E7RL 2N66A 1PE4A 2E3FA 1T7AA 1SN1A 1ZUTA 1KV0A 2GL1A 1I6FA 1PTXA 1C55A 4CQKA 2I61A 4AEIA 4HHFA 2KGQA 2N2RA 1LQHA 1ICAA 2KSKA 1DJTA 1B7DA 4AB0A 1JXCA 1T0ZA 1NRBA 1I6GA 2KBJA 1LQQA 1CHZA 1OZZA 1T1TA 5KK4A 2KBKA 2LT8A 1N4NA 1OMYA 1FH3A 1SEGA 1CN2A 2LJMA 1BMRA 1JZBA 1BK8A 1GPSA 2LY6A 1BRZA 1WT7A 2LI7A 2MZ0A
chains in the Genus database with same CATH superfamily
3SF4D 5BPLA 3KP0A 2SN3A 4UJ0A 3IUCA 2N2QA 2LKBA 2LR3A 5F1XA 1P0AA 5EXWA 2VY6A 1ZFUA 2BUPA 5AQTA 1BCGA 3E7UX 1TI5A 1ZVGA 4IO8A 1WMTA 4KYPA 5F0XA 1KAXA 1ZVEA 1ZYWA 1NGHA 2B3CA 3FZKA 3KOWA 3A8YA 2YIOA 1AYJA 3PSMA 3QMLA 5AQPA 3FZFA 4H5TA 5CY0A 1B3CA 4FL9A 5AQLA 3QFPA 3GKUA 4V1DC 2LY5A 2YIPA 3CQXA 5AQKA 5FPEA 2E3GA 4HWIA 2LJ7A 1C56A 1VNBA 4FSVA 2ATBA 1LQIA 3QFUA 1JZAA 2E2FA 1ATRA 2YEOA 3FZLA 4AAZA 2KYQA 1JKZA 1NE5A 1MR4A 2GMOA 1P00A 2M8BB 5FPNA 2E88A 2KPYA 1NRAA 1KAYA 1ZYVA 5AQJA 3KP1A 1NGAA 2MN5A 1SNBA 2NY9X 1NH5A 1T7EA 2YILA 3ATVA 1DQ7A 2QWPA 1ZU3A 4H5WA 5AQFA 5AQNA 2QWNA 3GDQA 1MYNA 2K35A 2V7ZA 3M3ZA 5AR0A 5EX5A 1VNAA 1NGJA 2QW9A 4H5VA 4H5RA 4UAEF 2KJAA 2ASCA 3R2VA 1KAZA 5F2RA 2NY8X 5BPNA 1I2VA 2QWQA 1NGGA 1DKGD 2YC1C 5AQOA 1AHOA 5AQQA 5BN9A 1I2UA 2E0HA 4UADE 1S3XA 2A7TA 1SN4A 3FZMA 1GPTA 1NPIA 1QQNA 2MBKA 4HE7A 1T7BA 1HX1A 2D56A 3KHWA 2YBRC 3BK3C 2QWOA 1L4VA 1NGDA 1WWNA 2N69A 1PX9A 2E8AA 3LDNA 2BRZA 1POIA 2LN8A 2B68A 2KBHA 4KBOA 1BUPA 2N66A 1PE4A 3E7RL 3FZHA 2E3FA 5AQHA 5AQWA 1HJOA 1T7AA 1SN1A 1HPMA 3KOXA 5EY4A 3L6QA 1ZUTA 2JDQD 1KV0A 5AQXA 3C7NB 1K8BA 3D2FB 2GL1A 1I6FA 1PTXA 3I33A 3KVGA 1C55A 4CQKA 2I61A 5AQRA 2G2KA 3FE1A 3D2FA 4AEIA 4HHFA 2KGQA 1XRSB 3LDOA 2N2RA 5FPMA 2QWMA 1NGEA 1LQHA 1YUWA 1ICAA 2KSKA 1UGLA 2QWLA 5AQIA 5BN8A 3LDPA 3KOZA 5AQGA 1B7DA 1DJTA 3HSCA 4AB0A 1NGCA 1JXCA 1T0ZA 4UAFE 1BA0A 1NRBA 1I6GA 2KBJA 5EVZA 1LQQA 1QQMA 5AQVA 1CHZA 5BPMA 3QI7A 1ATSA 1OZZA 1T1TA 1NGIA 2QWRA 3L56A 4GNIA 3KOYA 5KK4A 3D2EB 2KBKA 2LT8A 1N4NA 1OMYA 4H5NA 1FH3A 1SEGA 1NGFA 1CN2A 2LJMA 3JXUA 5AQMA 1BMRA 1JZBA 3D2EA 3L4IA 1QQOA 5FPDA 1BK8A 1GPSA 3ATUA 2LY6A 1BRZA 3C7NA 3KC6A 1WT7A 2LI7A 2MZ0A 5AQYA 5AQZA 5AQUA 5AQSA 2KHOA 1NGBA 3CW4A 1BA1A 3LDQA 3GL1A 2QXLA 3AY9A 3LDLA
chains in the Genus database with same CATH topology
4UJ0A 2SN3A 2N2QA 2LKBA 2LR3A 1P0AA 1ZFUA 1BCGA 3E7UX 1TI5A 1ZVGA 1WMTA 4KYPA 1ZVEA 1ZYWA 2B3CA 1AYJA 3PSMA 5CY0A 1B3CA 4V1DC 2LY5A 2E3GA 2LJ7A 1C56A 1VNBA 2ATBA 1LQIA 1JZAA 2YEOA 4AAZA 2KYQA 1JKZA 1NE5A 1MR4A 1P00A 2M8BB 2KPYA 1NRAA 1ZYVA 1SNBA 2NY9X 1NH5A 1T7EA 1DQ7A 1ZU3A 1MYNA 1VNAA 2KJAA 2ASCA 2NY8X 1I2VA 2YC1C 1AHOA 1I2UA 2E0HA 2A7TA 1SN4A 1GPTA 1NPIA 4HE7A 1T7BA 1L4VA 2YBRC 1WWNA 2N69A 1PX9A 2BRZA 2B68A 2KBHA 3E7RL 2N66A 1PE4A 2E3FA 1T7AA 1SN1A 1ZUTA 1KV0A 2GL1A 1I6FA 1PTXA 1C55A 4CQKA 2I61A 4AEIA 4HHFA 2KGQA 2N2RA 1LQHA 1ICAA 2KSKA 1DJTA 1B7DA 4AB0A 1JXCA 1T0ZA 1NRBA 1I6GA 2KBJA 1LQQA 1CHZA 1OZZA 1T1TA 5KK4A 2KBKA 2LT8A 1N4NA 1OMYA 1FH3A 1SEGA 1CN2A 2LJMA 1BMRA 1JZBA 1BK8A 1GPSA 2LY6A 1BRZA 1WT7A 2LI7A 2MZ0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4UJ0 A;  2SN3 A;  2N2Q A;  2LKB A;  2LR3 A;  1P0A A;  1ZFU A;  1BCG A;  3E7U X;  1TI5 A;  1ZVG A;  1WMT A;  4KYP A;  1ZVE A;  1ZYW A;  2B3C A;  1AYJ A;  3PSM A;  5CY0 A;  1B3C A;  4V1D C;  2LY5 A;  2E3G A;  2LJ7 A;  1C56 A;  1VNB A;  2ATB A;  1LQI A;  1JZA A;  2YEO A;  4AAZ A;  2KYQ A;  1JKZ A;  1NE5 A;  1MR4 A;  1P00 A;  2M8B B;  2KPY A;  1NRA A;  1ZYV A;  1SNB A;  2NY9 X;  1NH5 A;  1T7E A;  1DQ7 A;  1ZU3 A;  1MYN A;  1VNA A;  2KJA A;  2ASC A;  2NY8 X;  1I2V A;  2YC1 C;  1AHO A;  1I2U A;  2E0H A;  2A7T A;  1SN4 A;  1GPT A;  1NPI A;  4HE7 A;  1T7B A;  1L4V A;  2YBR C;  1WWN A;  2N69 A;  1PX9 A;  2BRZ A;  2B68 A;  2KBH A;  3E7R L;  2N66 A;  1PE4 A;  2E3F A;  1T7A A;  1SN1 A;  1ZUT A;  1KV0 A;  2GL1 A;  1I6F A;  1PTX A;  1C55 A;  4CQK A;  2I61 A;  4AEI A;  4HHF A;  2KGQ A;  2N2R A;  1LQH A;  1ICA A;  2KSK A;  1DJT A;  1B7D A;  4AB0 A;  1JXC A;  1T0Z A;  1NRB A;  1I6G A;  2KBJ A;  1LQQ A;  1CHZ A;  1OZZ A;  1T1T A;  5KK4 A;  2KBK A;  2LT8 A;  1N4N A;  1OMY A;  1FH3 A;  1SEG A;  1CN2 A;  2LJM A;  1BMR A;  1JZB A;  1BK8 A;  1GPS A;  2LY6 A;  1BRZ A;  1WT7 A;  2LI7 A;  2MZ0 A; 
#chains in the Genus database with same CATH topology
 3SF4 D;  5BPL A;  3KP0 A;  2SN3 A;  4UJ0 A;  3IUC A;  2N2Q A;  2LKB A;  2LR3 A;  5F1X A;  1P0A A;  5EXW A;  2VY6 A;  1ZFU A;  2BUP A;  5AQT A;  1BCG A;  3E7U X;  1TI5 A;  1ZVG A;  4IO8 A;  1WMT A;  4KYP A;  5F0X A;  1KAX A;  1ZVE A;  1ZYW A;  1NGH A;  2B3C A;  3FZK A;  3KOW A;  3A8Y A;  2YIO A;  1AYJ A;  3PSM A;  3QML A;  5AQP A;  3FZF A;  4H5T A;  5CY0 A;  1B3C A;  4FL9 A;  5AQL A;  3QFP A;  3GKU A;  4V1D C;  2LY5 A;  2YIP A;  3CQX A;  5AQK A;  5FPE A;  2E3G A;  4HWI A;  2LJ7 A;  1C56 A;  1VNB A;  4FSV A;  2ATB A;  1LQI A;  3QFU A;  1JZA A;  2E2F A;  1ATR A;  2YEO A;  3FZL A;  4AAZ A;  2KYQ A;  1JKZ A;  1NE5 A;  1MR4 A;  2GMO A;  1P00 A;  2M8B B;  5FPN A;  2E88 A;  2KPY A;  1NRA A;  1KAY A;  1ZYV A;  5AQJ A;  3KP1 A;  1NGA A;  2MN5 A;  1SNB A;  2NY9 X;  1NH5 A;  1T7E A;  2YIL A;  3ATV A;  1DQ7 A;  2QWP A;  1ZU3 A;  4H5W A;  5AQF A;  5AQN A;  2QWN A;  3GDQ A;  1MYN A;  2K35 A;  2V7Z A;  3M3Z A;  5AR0 A;  5EX5 A;  1VNA A;  1NGJ A;  2QW9 A;  4H5V A;  4H5R A;  4UAE F;  2KJA A;  2ASC A;  3R2V A;  1KAZ A;  5F2R A;  2NY8 X;  5BPN A;  1I2V A;  2QWQ A;  1NGG A;  1DKG D;  2YC1 C;  5AQO A;  1AHO A;  5AQQ A;  5BN9 A;  1I2U A;  2E0H A;  4UAD E;  1S3X A;  2A7T A;  1SN4 A;  3FZM A;  1GPT A;  1NPI A;  1QQN A;  2MBK A;  4HE7 A;  1T7B A;  1HX1 A;  2D56 A;  3KHW A;  2YBR C;  3BK3 C;  2QWO A;  1L4V A;  1NGD A;  1WWN A;  2N69 A;  1PX9 A;  2E8A A;  3LDN A;  2BRZ A;  1POI A;  2LN8 A;  2B68 A;  2KBH A;  4KBO A;  1BUP A;  2N66 A;  1PE4 A;  3E7R L;  3FZH A;  2E3F A;  5AQH A;  5AQW A;  1HJO A;  1T7A A;  1SN1 A;  1HPM A;  3KOX A;  5EY4 A;  3L6Q A;  1ZUT A;  2JDQ D;  1KV0 A;  5AQX A;  3C7N B;  1K8B A;  3D2F B;  2GL1 A;  1I6F A;  1PTX A;  3I33 A;  3KVG A;  1C55 A;  4CQK A;  2I61 A;  5AQR A;  2G2K A;  3FE1 A;  3D2F A;  4AEI A;  4HHF A;  2KGQ A;  1XRS B;  3LDO A;  2N2R A;  5FPM A;  2QWM A;  1NGE A;  1LQH A;  1YUW A;  1ICA A;  2KSK A;  1UGL A;  2QWL A;  5AQI A;  5BN8 A;  3LDP A;  3KOZ A;  5AQG A;  1B7D A;  1DJT A;  3HSC A;  4AB0 A;  1NGC A;  1JXC A;  1T0Z A;  4UAF E;  1BA0 A;  1NRB A;  1I6G A;  2KBJ A;  5EVZ A;  1LQQ A;  1QQM A;  5AQV A;  1CHZ A;  5BPM A;  3QI7 A;  1ATS A;  1OZZ A;  1T1T A;  1NGI A;  2QWR A;  3L56 A;  4GNI A;  3KOY A;  5KK4 A;  3D2E B;  2KBK A;  2LT8 A;  1N4N A;  1OMY A;  4H5N A;  1FH3 A;  1SEG A;  1NGF A;  1CN2 A;  2LJM A;  3JXU A;  5AQM A;  1BMR A;  1JZB A;  3D2E A;  3L4I A;  1QQO A;  5FPD A;  1BK8 A;  1GPS A;  3ATU A;  2LY6 A;  1BRZ A;  3C7N A;  3KC6 A;  1WT7 A;  2LI7 A;  2MZ0 A;  5AQY A;  5AQZ A;  5AQU A;  5AQS A;  2KHO A;  1NGB A;  3CW4 A;  1BA1 A;  3LDQ A;  3GL1 A;  2QXL A;  3AY9 A;  3LDL A; 
#chains in the Genus database with same CATH homology
 4UJ0 A;  2SN3 A;  2N2Q A;  2LKB A;  2LR3 A;  1P0A A;  1ZFU A;  1BCG A;  3E7U X;  1TI5 A;  1ZVG A;  1WMT A;  4KYP A;  1ZVE A;  1ZYW A;  2B3C A;  1AYJ A;  3PSM A;  5CY0 A;  1B3C A;  4V1D C;  2LY5 A;  2E3G A;  2LJ7 A;  1C56 A;  1VNB A;  2ATB A;  1LQI A;  1JZA A;  2YEO A;  4AAZ A;  2KYQ A;  1JKZ A;  1NE5 A;  1MR4 A;  1P00 A;  2M8B B;  2KPY A;  1NRA A;  1ZYV A;  1SNB A;  2NY9 X;  1NH5 A;  1T7E A;  1DQ7 A;  1ZU3 A;  1MYN A;  1VNA A;  2KJA A;  2ASC A;  2NY8 X;  1I2V A;  2YC1 C;  1AHO A;  1I2U A;  2E0H A;  2A7T A;  1SN4 A;  1GPT A;  1NPI A;  4HE7 A;  1T7B A;  1L4V A;  2YBR C;  1WWN A;  2N69 A;  1PX9 A;  2BRZ A;  2B68 A;  2KBH A;  3E7R L;  2N66 A;  1PE4 A;  2E3F A;  1T7A A;  1SN1 A;  1ZUT A;  1KV0 A;  2GL1 A;  1I6F A;  1PTX A;  1C55 A;  4CQK A;  2I61 A;  4AEI A;  4HHF A;  2KGQ A;  2N2R A;  1LQH A;  1ICA A;  2KSK A;  1DJT A;  1B7D A;  4AB0 A;  1JXC A;  1T0Z A;  1NRB A;  1I6G A;  2KBJ A;  1LQQ A;  1CHZ A;  1OZZ A;  1T1T A;  5KK4 A;  2KBK A;  2LT8 A;  1N4N A;  1OMY A;  1FH3 A;  1SEG A;  1CN2 A;  2LJM A;  1BMR A;  1JZB A;  1BK8 A;  1GPS A;  2LY6 A;  1BRZ A;  1WT7 A;  2LI7 A;  2MZ0 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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