2YBRC

Crystal structure of the human derived single chain antibody fragment (scfv) 9004g in complex with cn2 toxin from the scorpion centruroides noxius hoffmann
Total Genus 15
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
15
sequence length
65
structure length
65
Chain Sequence
KEGYLVDKNTGCKYECLKLGDNDYCLRECKQQYGKGAGGYCYAFACWCTHLYEQAIVWPLPNKRC
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Basis of Neutralization of the Major Toxic Component from the Scorpion Centruroides Noxius Hoffmann by a Human-Derived Single Chain Antibody Fragment
pubmed doi rcsb
molecule tags Immune system/toxin
source organism Homo sapiens
molecule keywords SINGLE CHAIN ANTIBODY FRAGMENT 9004G
total genus 15
structure length 65
sequence length 65
chains with identical sequence F, I
ec nomenclature
pdb deposition date 2011-03-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF00537 Toxin_3 Scorpion toxin-like domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.30.10 Alpha Beta 2-Layer Sandwich Defensin A-like Knottin, scorpion toxin-like 2ybrC00
2N66A 1B3CA 1NRBA 1I6FA 1FH3A 1VNAA 1SN4A 1ZYWA 1LQHA 1OMYA 2E3FA 2SN3A 1T7AA 2N2RA 1GPSA 1OZZA 1C55A 2NY8X 1JZAA 1ZU3A 1NE5A 2B3CA 1ICAA 2YC1C 3E7RL 2E0HA 1BMRA 2KBHA 1NH5A 2YBRC 1WMTA 1P0AA 4CQKA 2LJMA 1L4VA 1ZVGA 1C56A 1B7DA 1PTXA 1PX9A 1WT7A 1DJTA 1ZYVA 2LJ7A 2LKBA 5KK4A 1I6GA 1P00A 1T1TA 1JXCA 1BCGA 2KPYA 1JZBA 1ZUTA 1LQIA 2KSKA 1NPIA 1LQQA 2KBKA 2LT8A 2LY6A 1SEGA 4V1DC 1PE4A 2KBJA 3PSMA 2KYQA 4HHFA 1ZFUA 2N69A 2E3GA 2KJAA 4AEIA 2ASCA 2GL1A 1AHOA 1MYNA 1T7EA 2N2QA 1TI5A 2LY5A 4UJ0A 4AB0A 2KGQA 1T0ZA 2BRZA 1I2VA 1GPTA 1KV0A 1DQ7A 2YEOA 1BK8A 2NY9X 2B68A 1VNBA 1AYJA 5CY0A 4AAZA 1WWNA 1NRAA 4HE7A 1JKZA 4KYPA 3E7UX 1SNBA 1I2UA 2A7TA 1MR4A 2LI7A 2I61A 2M8BB 1BRZA 1CHZA 1N4NA 1T7BA 2ATBA 1ZVEA 1CN2A 2MZ0A 1SN1A 2LR3A
chains in the Genus database with same CATH superfamily
2N66A 1B3CA 3LDLA 1NRBA 5AQZA 1I6FA 1QQNA 1FH3A 5FPDA 1VNAA 1SN4A 1ZYWA 1LQHA 2E8AA 1OMYA 3BK3C 3C7NA 3GL1A 2E2FA 2E3FA 5AQUA 4H5VA 2SN3A 1T7AA 2N2RA 1GPSA 1OZZA 1C55A 2JDQD 2NY8X 1JZAA 1ZU3A 5AQQA 2QW9A 1NE5A 4H5WA 5AQHA 2B3CA 2K35A 3CQXA 1ICAA 2YC1C 1UGLA 3AY9A 2QWRA 3E7RL 5AQLA 2V7ZA 2E0HA 4H5NA 1BMRA 2KBHA 1QQOA 1NH5A 5AQOA 2QWPA 5AQGA 1NGGA 5AQXA 5F2RA 5BN9A 3JXUA 2YBRC 1WMTA 1P0AA 5AQFA 5EX5A 4CQKA 1S3XA 4UAEF 2GMOA 2QWMA 3I33A 5AQKA 1NGFA 1NGAA 2LJMA 1ZVGA 1L4VA 1C56A 1B7DA 1PTXA 1NGEA 1PX9A 2LR3A 3KC6A 1WT7A 2E88A 3CW4A 4UAFE 3LDOA 1DJTA 1KAXA 2QWLA 2BUPA 1ZYVA 2LJ7A 3D2EA 5EXWA 5F0XA 2LKBA 5AQJA 5KK4A 1P00A 1I6GA 1KAYA 1T1TA 1JXCA 1BCGA 3KOZA 3QFUA 2KPYA 4FL9A 3FZHA 1XRSB 1JZBA 1ZUTA 3ATUA 1LQIA 1POIA 3GKUA 2KSKA 4UADE 1NGJA 1NPIA 1LQQA 1DKGD 3L4IA 2KBKA 2MN5A 2VY6A 1BA0A 3R2VA 1HPMA 3FZKA 3KP0A 1BUPA 3FE1A 5F1XA 2LT8A 3D2FB 2LY6A 1NGIA 1SEGA 4V1DC 3FZFA 1PE4A 3KOYA 5AQNA 2KBJA 3PSMA 3QMLA 2KYQA 2MBKA 1ZFUA 4HHFA 5AQYA 5AQWA 2N69A 2E3GA 5AQSA 2KJAA 5AQIA 4FSVA 4AEIA 2ASCA 5FPMA 2GL1A 1BA1A 2QWNA 1AHOA 3L6QA 2YIOA 3C7NB 3KOWA 3LDPA 3FZMA 5AQPA 1MYNA 1T7EA 2N2QA 3GDQA 3QI7A 5BPNA 2D56A 1TI5A 2LY5A 4UJ0A 5BPMA 2QWOA 4GNIA 2QWQA 4AB0A 1ATSA 2KGQA 4HWIA 1T0ZA 4H5TA 2QXLA 5FPNA 2BRZA 1I2VA 5AQMA 4KBOA 1K8BA 2KHOA 1HJOA 1GPTA 1KV0A 5AR0A 1DQ7A 1YUWA 2YEOA 1NGDA 1ATRA 1BK8A 2NY9X 2B68A 3A8YA 3IUCA 3KVGA 5AQVA 1KAZA 1VNBA 1AYJA 5CY0A 5FPEA 3QFPA 4AAZA 3L56A 3KHWA 1WWNA 1NGHA 1NRAA 2G2KA 4HE7A 5AQRA 2LN8A 1JKZA 4KYPA 3ATVA 3HSCA 3E7UX 5EVZA 3LDQA 3KP1A 3M3ZA 4H5RA 1SNBA 3D2EB 1I2UA 2A7TA 1MR4A 4IO8A 2LI7A 1NGCA 2I61A 2YILA 2M8BB 5AQTA 1BRZA 2YIPA 5BPLA 5EY4A 3SF4D 1HX1A 3D2FA 1QQMA 1CHZA 1N4NA 3FZLA 1T7BA 3KOXA 2ATBA 1ZVEA 1CN2A 5BN8A 2MZ0A 1SN1A 3LDNA 1NGBA
chains in the Genus database with same CATH topology
2N66A 1B3CA 1NRBA 1I6FA 1FH3A 1VNAA 1SN4A 1ZYWA 1LQHA 1OMYA 2E3FA 2SN3A 1T7AA 2N2RA 1GPSA 1OZZA 1C55A 2NY8X 1JZAA 1ZU3A 1NE5A 2B3CA 1ICAA 2YC1C 3E7RL 2E0HA 1BMRA 2KBHA 1NH5A 2YBRC 1WMTA 1P0AA 4CQKA 2LJMA 1L4VA 1ZVGA 1C56A 1B7DA 1PTXA 1PX9A 1WT7A 1DJTA 1ZYVA 2LJ7A 2LKBA 5KK4A 1I6GA 1P00A 1T1TA 1JXCA 1BCGA 2KPYA 1JZBA 1ZUTA 1LQIA 2KSKA 1NPIA 1LQQA 2KBKA 2LT8A 2LY6A 1SEGA 4V1DC 1PE4A 2KBJA 3PSMA 2KYQA 4HHFA 1ZFUA 2N69A 2E3GA 2KJAA 4AEIA 2ASCA 2GL1A 1AHOA 1MYNA 1T7EA 2N2QA 1TI5A 2LY5A 4UJ0A 4AB0A 2KGQA 1T0ZA 2BRZA 1I2VA 1GPTA 1KV0A 1DQ7A 2YEOA 1BK8A 2NY9X 2B68A 1VNBA 1AYJA 5CY0A 4AAZA 1WWNA 1NRAA 4HE7A 1JKZA 4KYPA 3E7UX 1SNBA 1I2UA 2A7TA 1MR4A 2LI7A 2I61A 2M8BB 1BRZA 1CHZA 1N4NA 1T7BA 2ATBA 1ZVEA 1CN2A 2MZ0A 1SN1A 2LR3A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2N66 A;  1B3C A;  1NRB A;  1I6F A;  1FH3 A;  1VNA A;  1SN4 A;  1ZYW A;  1LQH A;  1OMY A;  2E3F A;  2SN3 A;  1T7A A;  2N2R A;  1GPS A;  1OZZ A;  1C55 A;  2NY8 X;  1JZA A;  1ZU3 A;  1NE5 A;  2B3C A;  1ICA A;  2YC1 C;  3E7R L;  2E0H A;  1BMR A;  2KBH A;  1NH5 A;  2YBR C;  1WMT A;  1P0A A;  4CQK A;  2LJM A;  1L4V A;  1ZVG A;  1C56 A;  1B7D A;  1PTX A;  1PX9 A;  1WT7 A;  1DJT A;  1ZYV A;  2LJ7 A;  2LKB A;  5KK4 A;  1I6G A;  1P00 A;  1T1T A;  1JXC A;  1BCG A;  2KPY A;  1JZB A;  1ZUT A;  1LQI A;  2KSK A;  1NPI A;  1LQQ A;  2KBK A;  2LT8 A;  2LY6 A;  1SEG A;  4V1D C;  1PE4 A;  2KBJ A;  3PSM A;  2KYQ A;  4HHF A;  1ZFU A;  2N69 A;  2E3G A;  2KJA A;  4AEI A;  2ASC A;  2GL1 A;  1AHO A;  1MYN A;  1T7E A;  2N2Q A;  1TI5 A;  2LY5 A;  4UJ0 A;  4AB0 A;  2KGQ A;  1T0Z A;  2BRZ A;  1I2V A;  1GPT A;  1KV0 A;  1DQ7 A;  2YEO A;  1BK8 A;  2NY9 X;  2B68 A;  1VNB A;  1AYJ A;  5CY0 A;  4AAZ A;  1WWN A;  1NRA A;  4HE7 A;  1JKZ A;  4KYP A;  3E7U X;  1SNB A;  1I2U A;  2A7T A;  1MR4 A;  2LI7 A;  2I61 A;  2M8B B;  1BRZ A;  1CHZ A;  1N4N A;  1T7B A;  2ATB A;  1ZVE A;  1CN2 A;  2MZ0 A;  1SN1 A;  2LR3 A; 
#chains in the Genus database with same CATH topology
 2N66 A;  1B3C A;  3LDL A;  1NRB A;  5AQZ A;  1I6F A;  1QQN A;  1FH3 A;  5FPD A;  1VNA A;  1SN4 A;  1ZYW A;  1LQH A;  2E8A A;  1OMY A;  3BK3 C;  3C7N A;  3GL1 A;  2E2F A;  2E3F A;  5AQU A;  4H5V A;  2SN3 A;  1T7A A;  2N2R A;  1GPS A;  1OZZ A;  1C55 A;  2JDQ D;  2NY8 X;  1JZA A;  1ZU3 A;  5AQQ A;  2QW9 A;  1NE5 A;  4H5W A;  5AQH A;  2B3C A;  2K35 A;  3CQX A;  1ICA A;  2YC1 C;  1UGL A;  3AY9 A;  2QWR A;  3E7R L;  5AQL A;  2V7Z A;  2E0H A;  4H5N A;  1BMR A;  2KBH A;  1QQO A;  1NH5 A;  5AQO A;  2QWP A;  5AQG A;  1NGG A;  5AQX A;  5F2R A;  5BN9 A;  3JXU A;  2YBR C;  1WMT A;  1P0A A;  5AQF A;  5EX5 A;  4CQK A;  1S3X A;  4UAE F;  2GMO A;  2QWM A;  3I33 A;  5AQK A;  1NGF A;  1NGA A;  2LJM A;  1ZVG A;  1L4V A;  1C56 A;  1B7D A;  1PTX A;  1NGE A;  1PX9 A;  2LR3 A;  3KC6 A;  1WT7 A;  2E88 A;  3CW4 A;  4UAF E;  3LDO A;  1DJT A;  1KAX A;  2QWL A;  2BUP A;  1ZYV A;  2LJ7 A;  3D2E A;  5EXW A;  5F0X A;  2LKB A;  5AQJ A;  5KK4 A;  1P00 A;  1I6G A;  1KAY A;  1T1T A;  1JXC A;  1BCG A;  3KOZ A;  3QFU A;  2KPY A;  4FL9 A;  3FZH A;  1XRS B;  1JZB A;  1ZUT A;  3ATU A;  1LQI A;  1POI A;  3GKU A;  2KSK A;  4UAD E;  1NGJ A;  1NPI A;  1LQQ A;  1DKG D;  3L4I A;  2KBK A;  2MN5 A;  2VY6 A;  1BA0 A;  3R2V A;  1HPM A;  3FZK A;  3KP0 A;  1BUP A;  3FE1 A;  5F1X A;  2LT8 A;  3D2F B;  2LY6 A;  1NGI A;  1SEG A;  4V1D C;  3FZF A;  1PE4 A;  3KOY A;  5AQN A;  2KBJ A;  3PSM A;  3QML A;  2KYQ A;  2MBK A;  1ZFU A;  4HHF A;  5AQY A;  5AQW A;  2N69 A;  2E3G A;  5AQS A;  2KJA A;  5AQI A;  4FSV A;  4AEI A;  2ASC A;  5FPM A;  2GL1 A;  1BA1 A;  2QWN A;  1AHO A;  3L6Q A;  2YIO A;  3C7N B;  3KOW A;  3LDP A;  3FZM A;  5AQP A;  1MYN A;  1T7E A;  2N2Q A;  3GDQ A;  3QI7 A;  5BPN A;  2D56 A;  1TI5 A;  2LY5 A;  4UJ0 A;  5BPM A;  2QWO A;  4GNI A;  2QWQ A;  4AB0 A;  1ATS A;  2KGQ A;  4HWI A;  1T0Z A;  4H5T A;  2QXL A;  5FPN A;  2BRZ A;  1I2V A;  5AQM A;  4KBO A;  1K8B A;  2KHO A;  1HJO A;  1GPT A;  1KV0 A;  5AR0 A;  1DQ7 A;  1YUW A;  2YEO A;  1NGD A;  1ATR A;  1BK8 A;  2NY9 X;  2B68 A;  3A8Y A;  3IUC A;  3KVG A;  5AQV A;  1KAZ A;  1VNB A;  1AYJ A;  5CY0 A;  5FPE A;  3QFP A;  4AAZ A;  3L56 A;  3KHW A;  1WWN A;  1NGH A;  1NRA A;  2G2K A;  4HE7 A;  5AQR A;  2LN8 A;  1JKZ A;  4KYP A;  3ATV A;  3HSC A;  3E7U X;  5EVZ A;  3LDQ A;  3KP1 A;  3M3Z A;  4H5R A;  1SNB A;  3D2E B;  1I2U A;  2A7T A;  1MR4 A;  4IO8 A;  2LI7 A;  1NGC A;  2I61 A;  2YIL A;  2M8B B;  5AQT A;  1BRZ A;  2YIP A;  5BPL A;  5EY4 A;  3SF4 D;  1HX1 A;  3D2F A;  1QQM A;  1CHZ A;  1N4N A;  3FZL A;  1T7B A;  3KOX A;  2ATB A;  1ZVE A;  1CN2 A;  5BN8 A;  2MZ0 A;  1SN1 A;  3LDN A;  1NGB A; 
#chains in the Genus database with same CATH homology
 2N66 A;  1B3C A;  1NRB A;  1I6F A;  1FH3 A;  1VNA A;  1SN4 A;  1ZYW A;  1LQH A;  1OMY A;  2E3F A;  2SN3 A;  1T7A A;  2N2R A;  1GPS A;  1OZZ A;  1C55 A;  2NY8 X;  1JZA A;  1ZU3 A;  1NE5 A;  2B3C A;  1ICA A;  2YC1 C;  3E7R L;  2E0H A;  1BMR A;  2KBH A;  1NH5 A;  2YBR C;  1WMT A;  1P0A A;  4CQK A;  2LJM A;  1L4V A;  1ZVG A;  1C56 A;  1B7D A;  1PTX A;  1PX9 A;  1WT7 A;  1DJT A;  1ZYV A;  2LJ7 A;  2LKB A;  5KK4 A;  1I6G A;  1P00 A;  1T1T A;  1JXC A;  1BCG A;  2KPY A;  1JZB A;  1ZUT A;  1LQI A;  2KSK A;  1NPI A;  1LQQ A;  2KBK A;  2LT8 A;  2LY6 A;  1SEG A;  4V1D C;  1PE4 A;  2KBJ A;  3PSM A;  2KYQ A;  4HHF A;  1ZFU A;  2N69 A;  2E3G A;  2KJA A;  4AEI A;  2ASC A;  2GL1 A;  1AHO A;  1MYN A;  1T7E A;  2N2Q A;  1TI5 A;  2LY5 A;  4UJ0 A;  4AB0 A;  2KGQ A;  1T0Z A;  2BRZ A;  1I2V A;  1GPT A;  1KV0 A;  1DQ7 A;  2YEO A;  1BK8 A;  2NY9 X;  2B68 A;  1VNB A;  1AYJ A;  5CY0 A;  4AAZ A;  1WWN A;  1NRA A;  4HE7 A;  1JKZ A;  4KYP A;  3E7U X;  1SNB A;  1I2U A;  2A7T A;  1MR4 A;  2LI7 A;  2I61 A;  2M8B B;  1BRZ A;  1CHZ A;  1N4N A;  1T7B A;  2ATB A;  1ZVE A;  1CN2 A;  2MZ0 A;  1SN1 A;  2LR3 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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