2YEO | Genus

Total Genus 15

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	15
sequence length	65
structure length	65
Chain Sequence	MVRDAYIAKNYNCVYECFRDAYCNELCTKNGASSGYCQWLGKYGNACWCYALPDNVPIRVPGKCR

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Toxin
source organism	Leiurus quinquestriatus hebraeus
publication title	Crystal Structures of Scorpion Alpha-Toxinsmutants Reveal Conformational Constraints that Dictate Preference for Mammalian Brain Voltage-Gated Na- Channels rcsb
molecule keywords	ALPHA-INSECT TOXIN LQHAIT
total genus	15
structure length	65
sequence length	65
ec nomenclature
pdb deposition date	2011-03-28

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00537	Toxin_3	Scorpion toxin-like domain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.30.30.10	Alpha Beta	2-Layer Sandwich	Defensin A-like	Knottin, scorpion toxin-like	2yeoA00

1SEGA 1JXCA 2YC1C 1MYNA 1GPSA 1AHOA 1P0AA 1LQHA 1I6FA 2LR3A 1VNAA 2KYQA 4KYPA 1LQQA 1WT7A 2N2QA 2KBKA 2NY9X 1VNBA 2MZ0A 1NPIA 2E3GA 4UJ0A 2N69A 1C56A 1B3CA 1N4NA 2E3FA 1BK8A 2E0HA 1L4VA 1T0ZA 2NY8X 1I2VA 1ZVEA 1TI5A 1ZVGA 2KBHA 2LY5A 2LY6A 1JKZA 1BMRA 1OZZA 4AEIA 1GPTA 1LQIA 1WWNA 1DJTA 1FH3A 1BCGA 1ICAA 1ZFUA 4HHFA 2ASCA 1ZUTA 2ATBA 1SNBA 1I2UA 5CY0A 1T7AA 2M8BB 2KGQA 1NRBA 1SN1A 3E7UX 1BRZA 1ZYVA 1ZYWA 1NRAA 2LJ7A 2I61A 4CQKA 4V1DC 4AB0A 1PE4A 1KV0A 2SN3A 2KJAA 1NH5A 5KK4A 2A7TA 2LJMA 3PSMA 1ZU3A 1AYJA 2LKBA 2N66A 2N2RA 2YBRC 1SN4A 2B68A 1I6GA 1C55A 2KSKA 2KBJA 1CHZA 4AAZA 1P00A 1T7BA 2KPYA 2BRZA 1PTXA 1WMTA 1MR4A 2LT8A 2GL1A 1PX9A 1JZAA 1B7DA 2LI7A 1T1TA 2B3CA 1JZBA 1OMYA 2YEOA 4HE7A 1DQ7A 1T7EA 1CN2A 3E7RL 1NE5A
chains in the Genus database with same CATH superfamily

5FPEA 5FPNA 1SEGA 2MN5A 1JXCA 1HJOA 2QWPA 5AQRA 2YILA 2YC1C 3KVGA 1MYNA 3CQXA 1YUWA 1NGFA 3L56A 3LDPA 1KAXA 1GPSA 1AHOA 1BMRA 1P0AA 1LQHA 1NGDA 2JDQD 5BPLA 5AQQA 2E88A 5AQXA 5F0XA 1I6FA 5AQGA 2LR3A 1VNAA 3ATVA 2KYQA 4KYPA 3L4IA 5BPMA 2KHOA 5BPNA 1LQQA 1WT7A 1XRSB 1QQMA 2KBKA 2G2KA 2N2QA 2NY9X 1HPMA 2D56A 5EVZA 1VNBA 2MZ0A 1NGJA 1NPIA 5AQFA 5F1XA 4FL9A 2E3GA 4UJ0A 4H5NA 2N69A 1C56A 2LN8A 1B3CA 1NGBA 3L6QA 5AQVA 5AR0A 4H5RA 1NGEA 1N4NA 2E3FA 1BK8A 1JKZA 2E0HA 3FZKA 1L4VA 1ATSA 1T0ZA 2NY8X 3KOYA 5AQZA 3GDQA 3LDQA 5F2RA 1I2VA 4UAFE 1ZVEA 4UAEF 5AQHA 3LDLA 3KP0A 1TI5A 1ZVGA 3M3ZA 3GKUA 2KBHA 2LY5A 2LY6A 3AY9A 4GNIA 5AQOA 5FPDA 1BUPA 2V7ZA 3QFPA 3R2VA 4UADE 1OZZA 4AEIA 5AQWA 5BN9A 1GPTA 1LQIA 1WWNA 2E8AA 1DJTA 1KAYA 1NGIA 1HX1A 1FH3A 4KBOA 1BCGA 1ICAA 3QMLA 1ZFUA 1POIA 1NGAA 1SNBA 1ZUTA 2ASCA 2ATBA 2BUPA 3FE1A 3KOZA 3KP1A 4HHFA 1I2UA 4FSVA 2K35A 3I33A 4H5TA 5AQIA 5CY0A 1T7AA 1BA0A 2MBKA 2YIOA 2M8BB 3C7NB 2KGQA 3HSCA 1NRBA 1SN1A 2GMOA 3E7UX 1BRZA 1QQOA 1ZYVA 3ATUA 5AQYA 1ZYWA 3D2FA 5AQNA 4IO8A 3QI7A 4H5WA 1NRAA 2LJ7A 1QQNA 1NGHA 2I61A 2QWMA 1K8BA 2QWNA 4CQKA 5EY4A 3SF4D 4V1DC 2YIPA 3D2EB 4AB0A 1PE4A 1KV0A 5AQKA 3D2FB 3KOWA 2SN3A 2KJAA 1NH5A 1DKGD 4H5VA 5KK4A 1KAZA 2A7TA 2LJMA 2QWQA 2QW9A 3PSMA 1ZU3A 3C7NA 1AYJA 2LKBA 1S3XA 2N66A 1UGLA 3KC6A 2N2RA 3GL1A 5AQSA 3FZFA 2YBRC 2E2FA 3FZLA 1SN4A 2B68A 3QFUA 5AQPA 5AQMA 1I6GA 1C55A 1NGGA 2KSKA 2KBJA 1CHZA 2VY6A 3IUCA 5EX5A 5FPMA 3JXUA 4AAZA 1P00A 1T7BA 2KPYA 3D2EA 5BN8A 3FZMA 3FZHA 2BRZA 3LDOA 1NGCA 1PTXA 5AQTA 1WMTA 2QWLA 5AQLA 1MR4A 1ATRA 2LT8A 2QWOA 2QWRA 2QXLA 2GL1A 3A8YA 3CW4A 1PX9A 1JZAA 3KOXA 1BA1A 1B7DA 2LI7A 1T1TA 3LDNA 4HWIA 5EXWA 5AQJA 5AQUA 2B3CA 3KHWA 1JZBA 1OMYA 2YEOA 4HE7A 1DQ7A 3BK3C 1T7EA 1CN2A 3E7RL 1NE5A
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 1SEG A;  1JXC A;  2YC1 C;  1MYN A;  1GPS A;  1AHO A;  1P0A A;  1LQH A;  1I6F A;  2LR3 A;  1VNA A;  2KYQ A;  4KYP A;  1LQQ A;  1WT7 A;  2N2Q A;  2KBK A;  2NY9 X;  1VNB A;  2MZ0 A;  1NPI A;  2E3G A;  4UJ0 A;  2N69 A;  1C56 A;  1B3C A;  1N4N A;  2E3F A;  1BK8 A;  2E0H A;  1L4V A;  1T0Z A;  2NY8 X;  1I2V A;  1ZVE A;  1TI5 A;  1ZVG A;  2KBH A;  2LY5 A;  2LY6 A;  1JKZ A;  1BMR A;  1OZZ A;  4AEI A;  1GPT A;  1LQI A;  1WWN A;  1DJT A;  1FH3 A;  1BCG A;  1ICA A;  1ZFU A;  4HHF A;  2ASC A;  1ZUT A;  2ATB A;  1SNB A;  1I2U A;  5CY0 A;  1T7A A;  2M8B B;  2KGQ A;  1NRB A;  1SN1 A;  3E7U X;  1BRZ A;  1ZYV A;  1ZYW A;  1NRA A;  2LJ7 A;  2I61 A;  4CQK A;  4V1D C;  4AB0 A;  1PE4 A;  1KV0 A;  2SN3 A;  2KJA A;  1NH5 A;  5KK4 A;  2A7T A;  2LJM A;  3PSM A;  1ZU3 A;  1AYJ A;  2LKB A;  2N66 A;  2N2R A;  2YBR C;  1SN4 A;  2B68 A;  1I6G A;  1C55 A;  2KSK A;  2KBJ A;  1CHZ A;  4AAZ A;  1P00 A;  1T7B A;  2KPY A;  2BRZ A;  1PTX A;  1WMT A;  1MR4 A;  2LT8 A;  2GL1 A;  1PX9 A;  1JZA A;  1B7D A;  2LI7 A;  1T1T A;  2B3C A;  1JZB A;  1OMY A;  2YEO A;  4HE7 A;  1DQ7 A;  1T7E A;  1CN2 A;  3E7R L;  1NE5 A; 
#chains in the Genus database with same CATH topology
 5FPE A;  5FPN A;  1SEG A;  2MN5 A;  1JXC A;  1HJO A;  2QWP A;  5AQR A;  2YIL A;  2YC1 C;  3KVG A;  1MYN A;  3CQX A;  1YUW A;  1NGF A;  3L56 A;  3LDP A;  1KAX A;  1GPS A;  1AHO A;  1BMR A;  1P0A A;  1LQH A;  1NGD A;  2JDQ D;  5BPL A;  5AQQ A;  2E88 A;  5AQX A;  5F0X A;  1I6F A;  5AQG A;  2LR3 A;  1VNA A;  3ATV A;  2KYQ A;  4KYP A;  3L4I A;  5BPM A;  2KHO A;  5BPN A;  1LQQ A;  1WT7 A;  1XRS B;  1QQM A;  2KBK A;  2G2K A;  2N2Q A;  2NY9 X;  1HPM A;  2D56 A;  5EVZ A;  1VNB A;  2MZ0 A;  1NGJ A;  1NPI A;  5AQF A;  5F1X A;  4FL9 A;  2E3G A;  4UJ0 A;  4H5N A;  2N69 A;  1C56 A;  2LN8 A;  1B3C A;  1NGB A;  3L6Q A;  5AQV A;  5AR0 A;  4H5R A;  1NGE A;  1N4N A;  2E3F A;  1BK8 A;  1JKZ A;  2E0H A;  3FZK A;  1L4V A;  1ATS A;  1T0Z A;  2NY8 X;  3KOY A;  5AQZ A;  3GDQ A;  3LDQ A;  5F2R A;  1I2V A;  4UAF E;  1ZVE A;  4UAE F;  5AQH A;  3LDL A;  3KP0 A;  1TI5 A;  1ZVG A;  3M3Z A;  3GKU A;  2KBH A;  2LY5 A;  2LY6 A;  3AY9 A;  4GNI A;  5AQO A;  5FPD A;  1BUP A;  2V7Z A;  3QFP A;  3R2V A;  4UAD E;  1OZZ A;  4AEI A;  5AQW A;  5BN9 A;  1GPT A;  1LQI A;  1WWN A;  2E8A A;  1DJT A;  1KAY A;  1NGI A;  1HX1 A;  1FH3 A;  4KBO A;  1BCG A;  1ICA A;  3QML A;  1ZFU A;  1POI A;  1NGA A;  1SNB A;  1ZUT A;  2ASC A;  2ATB A;  2BUP A;  3FE1 A;  3KOZ A;  3KP1 A;  4HHF A;  1I2U A;  4FSV A;  2K35 A;  3I33 A;  4H5T A;  5AQI A;  5CY0 A;  1T7A A;  1BA0 A;  2MBK A;  2YIO A;  2M8B B;  3C7N B;  2KGQ A;  3HSC A;  1NRB A;  1SN1 A;  2GMO A;  3E7U X;  1BRZ A;  1QQO A;  1ZYV A;  3ATU A;  5AQY A;  1ZYW A;  3D2F A;  5AQN A;  4IO8 A;  3QI7 A;  4H5W A;  1NRA A;  2LJ7 A;  1QQN A;  1NGH A;  2I61 A;  2QWM A;  1K8B A;  2QWN A;  4CQK A;  5EY4 A;  3SF4 D;  4V1D C;  2YIP A;  3D2E B;  4AB0 A;  1PE4 A;  1KV0 A;  5AQK A;  3D2F B;  3KOW A;  2SN3 A;  2KJA A;  1NH5 A;  1DKG D;  4H5V A;  5KK4 A;  1KAZ A;  2A7T A;  2LJM A;  2QWQ A;  2QW9 A;  3PSM A;  1ZU3 A;  3C7N A;  1AYJ A;  2LKB A;  1S3X A;  2N66 A;  1UGL A;  3KC6 A;  2N2R A;  3GL1 A;  5AQS A;  3FZF A;  2YBR C;  2E2F A;  3FZL A;  1SN4 A;  2B68 A;  3QFU A;  5AQP A;  5AQM A;  1I6G A;  1C55 A;  1NGG A;  2KSK A;  2KBJ A;  1CHZ A;  2VY6 A;  3IUC A;  5EX5 A;  5FPM A;  3JXU A;  4AAZ A;  1P00 A;  1T7B A;  2KPY A;  3D2E A;  5BN8 A;  3FZM A;  3FZH A;  2BRZ A;  3LDO A;  1NGC A;  1PTX A;  5AQT A;  1WMT A;  2QWL A;  5AQL A;  1MR4 A;  1ATR A;  2LT8 A;  2QWO A;  2QWR A;  2QXL A;  2GL1 A;  3A8Y A;  3CW4 A;  1PX9 A;  1JZA A;  3KOX A;  1BA1 A;  1B7D A;  2LI7 A;  1T1T A;  3LDN A;  4HWI A;  5EXW A;  5AQJ A;  5AQU A;  2B3C A;  3KHW A;  1JZB A;  1OMY A;  2YEO A;  4HE7 A;  1DQ7 A;  3BK3 C;  1T7E A;  1CN2 A;  3E7R L;  1NE5 A; 
#chains in the Genus database with same CATH homology
 1SEG A;  1JXC A;  2YC1 C;  1MYN A;  1GPS A;  1AHO A;  1P0A A;  1LQH A;  1I6F A;  2LR3 A;  1VNA A;  2KYQ A;  4KYP A;  1LQQ A;  1WT7 A;  2N2Q A;  2KBK A;  2NY9 X;  1VNB A;  2MZ0 A;  1NPI A;  2E3G A;  4UJ0 A;  2N69 A;  1C56 A;  1B3C A;  1N4N A;  2E3F A;  1BK8 A;  2E0H A;  1L4V A;  1T0Z A;  2NY8 X;  1I2V A;  1ZVE A;  1TI5 A;  1ZVG A;  2KBH A;  2LY5 A;  2LY6 A;  1JKZ A;  1BMR A;  1OZZ A;  4AEI A;  1GPT A;  1LQI A;  1WWN A;  1DJT A;  1FH3 A;  1BCG A;  1ICA A;  1ZFU A;  4HHF A;  2ASC A;  1ZUT A;  2ATB A;  1SNB A;  1I2U A;  5CY0 A;  1T7A A;  2M8B B;  2KGQ A;  1NRB A;  1SN1 A;  3E7U X;  1BRZ A;  1ZYV A;  1ZYW A;  1NRA A;  2LJ7 A;  2I61 A;  4CQK A;  4V1D C;  4AB0 A;  1PE4 A;  1KV0 A;  2SN3 A;  2KJA A;  1NH5 A;  5KK4 A;  2A7T A;  2LJM A;  3PSM A;  1ZU3 A;  1AYJ A;  2LKB A;  2N66 A;  2N2R A;  2YBR C;  1SN4 A;  2B68 A;  1I6G A;  1C55 A;  2KSK A;  2KBJ A;  1CHZ A;  4AAZ A;  1P00 A;  1T7B A;  2KPY A;  2BRZ A;  1PTX A;  1WMT A;  1MR4 A;  2LT8 A;  2GL1 A;  1PX9 A;  1JZA A;  1B7D A;  2LI7 A;  1T1T A;  2B3C A;  1JZB A;  1OMY A;  2YEO A;  4HE7 A;  1DQ7 A;  1T7E A;  1CN2 A;  3E7R L;  1NE5 A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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2YEOA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations