2YC1C

Crystal structure of the human derived single chain antibody fragment (scfv) 9004g in complex with cn2 toxin from the scorpion centruroides noxius hoffmann
Total Genus 13
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
13
sequence length
65
structure length
65
Chain Sequence
KEGYLVDKNTGCKYECLKLGDNDYCLRECKQQYGKGAGGYCYAFACWCTHLYEQAIVWPLPNKRC
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Basis of Neutralization of the Major Toxic Component from the Scorpion Centruroides Noxius Hoffmann by a Human-Derived Single Chain Antibody Fragment.
pubmed doi rcsb
molecule tags Immune system/toxin
source organism Homo sapiens
molecule keywords SINGLE CHAIN ANTIBODY FRAGMENT 9004G
total genus 13
structure length 65
sequence length 65
chains with identical sequence F
ec nomenclature
pdb deposition date 2011-03-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF00537 Toxin_3 Scorpion toxin-like domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.30.10 Alpha Beta 2-Layer Sandwich Defensin A-like Knottin, scorpion toxin-like 2yc1C00
2YEOA 1OMYA 2N2QA 1PE4A 1ZYVA 1CHZA 2ASCA 1C55A 1LQHA 2LY6A 1MYNA 1LQQA 1N4NA 1JXCA 1FH3A 1T7AA 4AAZA 1P0AA 3PSMA 2LJMA 1SEGA 2YBRC 2NY8X 2M8BB 2LY5A 2LJ7A 2KBHA 2I61A 1NRAA 1PTXA 1ZUTA 1ZVEA 3E7RL 2B3CA 4HHFA 4HE7A 1VNBA 1B7DA 1GPTA 2N2RA 2N69A 2LT8A 2E3GA 1T1TA 1ZFUA 2SN3A 1T0ZA 1ZVGA 2KGQA 1NH5A 1TI5A 2ATBA 2KPYA 2KSKA 1I6GA 1ZU3A 1PX9A 2BRZA 1ZYWA 1DQ7A 2E3FA 2KBKA 1DJTA 2NY9X 2LR3A 1AHOA 1SN4A 2LKBA 1CN2A 1I2UA 1B3CA 1BCGA 1WMTA 1OZZA 3E7UX 2KJAA 2YC1C 1WT7A 2N66A 4KYPA 1SNBA 1BK8A 1MR4A 1P00A 2E0HA 4AB0A 2KBJA 1T7BA 1JKZA 4UJ0A 1AYJA 1LQIA 1NE5A 1BRZA 1NPIA 1KV0A 1GPSA 1T7EA 2MZ0A 1I6FA 4AEIA 1BMRA 1WWNA 1NRBA 1ICAA 1SN1A 2GL1A 1VNAA 4V1DC 5KK4A 1C56A 1JZAA 1JZBA 2KYQA 1I2VA 1L4VA 2A7TA 5CY0A 4CQKA 2LI7A 2B68A
chains in the Genus database with same CATH superfamily
2YEOA 2QWOA 4KBOA 1OMYA 1YUWA 1ATRA 2N2QA 1PE4A 2QWNA 2V7ZA 3FZFA 3I33A 1ZYVA 5AQXA 1CHZA 2ASCA 3KOXA 1C55A 1LQHA 2LY6A 1MYNA 1LQQA 1N4NA 3KP0A 1BA1A 1QQMA 5AQIA 5BPNA 1JXCA 1FH3A 3LDOA 3GL1A 1T7AA 3ATVA 3SF4D 1NGIA 4AAZA 5F0XA 1P0AA 4UAFE 3PSMA 2LJMA 1SEGA 1UGLA 3D2EA 1NGHA 2KHOA 4UAEF 2YBRC 2BUPA 2NY8X 3FZHA 3JXUA 2M8BB 2LY5A 1QQOA 2LJ7A 5KK4A 1POIA 1QQNA 2YIOA 4H5TA 2JDQD 2I61A 2KBHA 1NRAA 1PTXA 1XRSB 1ZUTA 1ZVEA 2QWMA 3E7RL 1BUPA 2B3CA 3AY9A 4FL9A 4HHFA 2GMOA 3KP1A 1NGJA 4HE7A 5AQJA 1NGEA 3CW4A 5AQMA 1VNBA 1B7DA 2YIPA 5AQUA 1NGFA 5AQLA 5AQRA 1GPTA 2N2RA 4GNIA 3CQXA 5EVZA 2N69A 2LT8A 2E3GA 5AQPA 2E88A 1T1TA 1ZFUA 2VY6A 3BK3C 3LDLA 5AQYA 1NGDA 2SN3A 1T0ZA 1ZVGA 2G2KA 2KGQA 1ATSA 1NH5A 3QI7A 3R2VA 4UADE 5BN9A 4HWIA 5AQTA 3A8YA 5F2RA 1TI5A 5BPMA 3D2EB 2ATBA 5EXWA 3FZKA 1DKGD 2KPYA 2QWRA 2KSKA 1I6GA 1ZU3A 1PX9A 3ATUA 2BRZA 2E2FA 1ZYWA 1HPMA 1DQ7A 2QWLA 5F1XA 3L4IA 2E3FA 3QFUA 3C7NA 3LDNA 4H5RA 5AQOA 5FPDA 2KBKA 1DJTA 2LN8A 2NY9X 1KAYA 2LR3A 4H5WA 1AHOA 1K8BA 1SN4A 3KC6A 2LKBA 1CN2A 3FE1A 3KOYA 1B3CA 1I2UA 5AQVA 3KHWA 5AQKA 1BCGA 1WMTA 1OZZA 3E7UX 2KJAA 2YC1C 1WT7A 2N66A 3LDQA 3KOWA 4KYPA 2QWPA 5EY4A 1BA0A 5FPEA 1SNBA 4IO8A 1BK8A 1MR4A 1P00A 2E0HA 4AB0A 2D56A 2KBJA 1T7BA 1JKZA 3FZMA 4UJ0A 2YILA 1AYJA 1LQIA 1NGGA 1NE5A 1BRZA 3QFPA 1KAZA 1NPIA 1KV0A 2E8AA 5AQGA 1GPSA 1S3XA 2MBKA 3C7NB 3QMLA 3D2FA 1T7EA 3D2FB 4FSVA 2MZ0A 5AQHA 5AR0A 1NGBA 5BPLA 1I6FA 3GDQA 4AEIA 1BMRA 1KAXA 1WWNA 5FPMA 3GKUA 3L6QA 1NRBA 3KVGA 5AQSA 1ICAA 1SN1A 3LDPA 4H5NA 3HSCA 2GL1A 5AQZA 1VNAA 3L56A 1HX1A 4H5VA 2K35A 1HJOA 1NGAA 1C56A 1JZAA 1JZBA 2KYQA 4V1DC 2MN5A 5AQFA 1I2VA 1L4VA 3FZLA 5BN8A 5AQQA 2A7TA 5CY0A 5AQWA 4CQKA 1NGCA 5EX5A 5AQNA 2QWQA 2QXLA 3M3ZA 2QW9A 2LI7A 3IUCA 3KOZA 5FPNA 2B68A
chains in the Genus database with same CATH topology
2YEOA 1OMYA 2N2QA 1PE4A 1ZYVA 1CHZA 2ASCA 1C55A 1LQHA 2LY6A 1MYNA 1LQQA 1N4NA 1JXCA 1FH3A 1T7AA 4AAZA 1P0AA 3PSMA 2LJMA 1SEGA 2YBRC 2NY8X 2M8BB 2LY5A 2LJ7A 2KBHA 2I61A 1NRAA 1PTXA 1ZUTA 1ZVEA 3E7RL 2B3CA 4HHFA 4HE7A 1VNBA 1B7DA 1GPTA 2N2RA 2N69A 2LT8A 2E3GA 1T1TA 1ZFUA 2SN3A 1T0ZA 1ZVGA 2KGQA 1NH5A 1TI5A 2ATBA 2KPYA 2KSKA 1I6GA 1ZU3A 1PX9A 2BRZA 1ZYWA 1DQ7A 2E3FA 2KBKA 1DJTA 2NY9X 2LR3A 1AHOA 1SN4A 2LKBA 1CN2A 1I2UA 1B3CA 1BCGA 1WMTA 1OZZA 3E7UX 2KJAA 2YC1C 1WT7A 2N66A 4KYPA 1SNBA 1BK8A 1MR4A 1P00A 2E0HA 4AB0A 2KBJA 1T7BA 1JKZA 4UJ0A 1AYJA 1LQIA 1NE5A 1BRZA 1NPIA 1KV0A 1GPSA 1T7EA 2MZ0A 1I6FA 4AEIA 1BMRA 1WWNA 1NRBA 1ICAA 1SN1A 2GL1A 1VNAA 4V1DC 5KK4A 1C56A 1JZAA 1JZBA 2KYQA 1I2VA 1L4VA 2A7TA 5CY0A 4CQKA 2LI7A 2B68A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2YEO A;  1OMY A;  2N2Q A;  1PE4 A;  1ZYV A;  1CHZ A;  2ASC A;  1C55 A;  1LQH A;  2LY6 A;  1MYN A;  1LQQ A;  1N4N A;  1JXC A;  1FH3 A;  1T7A A;  4AAZ A;  1P0A A;  3PSM A;  2LJM A;  1SEG A;  2YBR C;  2NY8 X;  2M8B B;  2LY5 A;  2LJ7 A;  2KBH A;  2I61 A;  1NRA A;  1PTX A;  1ZUT A;  1ZVE A;  3E7R L;  2B3C A;  4HHF A;  4HE7 A;  1VNB A;  1B7D A;  1GPT A;  2N2R A;  2N69 A;  2LT8 A;  2E3G A;  1T1T A;  1ZFU A;  2SN3 A;  1T0Z A;  1ZVG A;  2KGQ A;  1NH5 A;  1TI5 A;  2ATB A;  2KPY A;  2KSK A;  1I6G A;  1ZU3 A;  1PX9 A;  2BRZ A;  1ZYW A;  1DQ7 A;  2E3F A;  2KBK A;  1DJT A;  2NY9 X;  2LR3 A;  1AHO A;  1SN4 A;  2LKB A;  1CN2 A;  1I2U A;  1B3C A;  1BCG A;  1WMT A;  1OZZ A;  3E7U X;  2KJA A;  2YC1 C;  1WT7 A;  2N66 A;  4KYP A;  1SNB A;  1BK8 A;  1MR4 A;  1P00 A;  2E0H A;  4AB0 A;  2KBJ A;  1T7B A;  1JKZ A;  4UJ0 A;  1AYJ A;  1LQI A;  1NE5 A;  1BRZ A;  1NPI A;  1KV0 A;  1GPS A;  1T7E A;  2MZ0 A;  1I6F A;  4AEI A;  1BMR A;  1WWN A;  1NRB A;  1ICA A;  1SN1 A;  2GL1 A;  1VNA A;  4V1D C;  5KK4 A;  1C56 A;  1JZA A;  1JZB A;  2KYQ A;  1I2V A;  1L4V A;  2A7T A;  5CY0 A;  4CQK A;  2LI7 A;  2B68 A; 
#chains in the Genus database with same CATH topology
 2YEO A;  2QWO A;  4KBO A;  1OMY A;  1YUW A;  1ATR A;  2N2Q A;  1PE4 A;  2QWN A;  2V7Z A;  3FZF A;  3I33 A;  1ZYV A;  5AQX A;  1CHZ A;  2ASC A;  3KOX A;  1C55 A;  1LQH A;  2LY6 A;  1MYN A;  1LQQ A;  1N4N A;  3KP0 A;  1BA1 A;  1QQM A;  5AQI A;  5BPN A;  1JXC A;  1FH3 A;  3LDO A;  3GL1 A;  1T7A A;  3ATV A;  3SF4 D;  1NGI A;  4AAZ A;  5F0X A;  1P0A A;  4UAF E;  3PSM A;  2LJM A;  1SEG A;  1UGL A;  3D2E A;  1NGH A;  2KHO A;  4UAE F;  2YBR C;  2BUP A;  2NY8 X;  3FZH A;  3JXU A;  2M8B B;  2LY5 A;  1QQO A;  2LJ7 A;  5KK4 A;  1POI A;  1QQN A;  2YIO A;  4H5T A;  2JDQ D;  2I61 A;  2KBH A;  1NRA A;  1PTX A;  1XRS B;  1ZUT A;  1ZVE A;  2QWM A;  3E7R L;  1BUP A;  2B3C A;  3AY9 A;  4FL9 A;  4HHF A;  2GMO A;  3KP1 A;  1NGJ A;  4HE7 A;  5AQJ A;  1NGE A;  3CW4 A;  5AQM A;  1VNB A;  1B7D A;  2YIP A;  5AQU A;  1NGF A;  5AQL A;  5AQR A;  1GPT A;  2N2R A;  4GNI A;  3CQX A;  5EVZ A;  2N69 A;  2LT8 A;  2E3G A;  5AQP A;  2E88 A;  1T1T A;  1ZFU A;  2VY6 A;  3BK3 C;  3LDL A;  5AQY A;  1NGD A;  2SN3 A;  1T0Z A;  1ZVG A;  2G2K A;  2KGQ A;  1ATS A;  1NH5 A;  3QI7 A;  3R2V A;  4UAD E;  5BN9 A;  4HWI A;  5AQT A;  3A8Y A;  5F2R A;  1TI5 A;  5BPM A;  3D2E B;  2ATB A;  5EXW A;  3FZK A;  1DKG D;  2KPY A;  2QWR A;  2KSK A;  1I6G A;  1ZU3 A;  1PX9 A;  3ATU A;  2BRZ A;  2E2F A;  1ZYW A;  1HPM A;  1DQ7 A;  2QWL A;  5F1X A;  3L4I A;  2E3F A;  3QFU A;  3C7N A;  3LDN A;  4H5R A;  5AQO A;  5FPD A;  2KBK A;  1DJT A;  2LN8 A;  2NY9 X;  1KAY A;  2LR3 A;  4H5W A;  1AHO A;  1K8B A;  1SN4 A;  3KC6 A;  2LKB A;  1CN2 A;  3FE1 A;  3KOY A;  1B3C A;  1I2U A;  5AQV A;  3KHW A;  5AQK A;  1BCG A;  1WMT A;  1OZZ A;  3E7U X;  2KJA A;  2YC1 C;  1WT7 A;  2N66 A;  3LDQ A;  3KOW A;  4KYP A;  2QWP A;  5EY4 A;  1BA0 A;  5FPE A;  1SNB A;  4IO8 A;  1BK8 A;  1MR4 A;  1P00 A;  2E0H A;  4AB0 A;  2D56 A;  2KBJ A;  1T7B A;  1JKZ A;  3FZM A;  4UJ0 A;  2YIL A;  1AYJ A;  1LQI A;  1NGG A;  1NE5 A;  1BRZ A;  3QFP A;  1KAZ A;  1NPI A;  1KV0 A;  2E8A A;  5AQG A;  1GPS A;  1S3X A;  2MBK A;  3C7N B;  3QML A;  3D2F A;  1T7E A;  3D2F B;  4FSV A;  2MZ0 A;  5AQH A;  5AR0 A;  1NGB A;  5BPL A;  1I6F A;  3GDQ A;  4AEI A;  1BMR A;  1KAX A;  1WWN A;  5FPM A;  3GKU A;  3L6Q A;  1NRB A;  3KVG A;  5AQS A;  1ICA A;  1SN1 A;  3LDP A;  4H5N A;  3HSC A;  2GL1 A;  5AQZ A;  1VNA A;  3L56 A;  1HX1 A;  4H5V A;  2K35 A;  1HJO A;  1NGA A;  1C56 A;  1JZA A;  1JZB A;  2KYQ A;  4V1D C;  2MN5 A;  5AQF A;  1I2V A;  1L4V A;  3FZL A;  5BN8 A;  5AQQ A;  2A7T A;  5CY0 A;  5AQW A;  4CQK A;  1NGC A;  5EX5 A;  5AQN A;  2QWQ A;  2QXL A;  3M3Z A;  2QW9 A;  2LI7 A;  3IUC A;  3KOZ A;  5FPN A;  2B68 A; 
#chains in the Genus database with same CATH homology
 2YEO A;  1OMY A;  2N2Q A;  1PE4 A;  1ZYV A;  1CHZ A;  2ASC A;  1C55 A;  1LQH A;  2LY6 A;  1MYN A;  1LQQ A;  1N4N A;  1JXC A;  1FH3 A;  1T7A A;  4AAZ A;  1P0A A;  3PSM A;  2LJM A;  1SEG A;  2YBR C;  2NY8 X;  2M8B B;  2LY5 A;  2LJ7 A;  2KBH A;  2I61 A;  1NRA A;  1PTX A;  1ZUT A;  1ZVE A;  3E7R L;  2B3C A;  4HHF A;  4HE7 A;  1VNB A;  1B7D A;  1GPT A;  2N2R A;  2N69 A;  2LT8 A;  2E3G A;  1T1T A;  1ZFU A;  2SN3 A;  1T0Z A;  1ZVG A;  2KGQ A;  1NH5 A;  1TI5 A;  2ATB A;  2KPY A;  2KSK A;  1I6G A;  1ZU3 A;  1PX9 A;  2BRZ A;  1ZYW A;  1DQ7 A;  2E3F A;  2KBK A;  1DJT A;  2NY9 X;  2LR3 A;  1AHO A;  1SN4 A;  2LKB A;  1CN2 A;  1I2U A;  1B3C A;  1BCG A;  1WMT A;  1OZZ A;  3E7U X;  2KJA A;  2YC1 C;  1WT7 A;  2N66 A;  4KYP A;  1SNB A;  1BK8 A;  1MR4 A;  1P00 A;  2E0H A;  4AB0 A;  2KBJ A;  1T7B A;  1JKZ A;  4UJ0 A;  1AYJ A;  1LQI A;  1NE5 A;  1BRZ A;  1NPI A;  1KV0 A;  1GPS A;  1T7E A;  2MZ0 A;  1I6F A;  4AEI A;  1BMR A;  1WWN A;  1NRB A;  1ICA A;  1SN1 A;  2GL1 A;  1VNA A;  4V1D C;  5KK4 A;  1C56 A;  1JZA A;  1JZB A;  2KYQ A;  1I2V A;  1L4V A;  2A7T A;  5CY0 A;  4CQK A;  2LI7 A;  2B68 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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