3BK3C

Crystal structure of the complex of bmp-2 and the first von willebrand domain type c of crossveinless-2
Total Genus 8
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
8
sequence length
67
structure length
67
Chain Sequence
WLITGTEASCENEGEVLHIPNITDNPCISCVCLNQKAECKQEKCAPLAEDCALVVKQTGACCEKCKG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure analysis reveals how the Chordin family member crossveinless 2 blocks BMP-2 receptor binding
pubmed doi rcsb
molecule tags Hormone/growth factor
source organism Homo sapiens
molecule keywords Bone morphogenetic protein 2
total genus 8
structure length 67
sequence length 67
chains with identical sequence D
ec nomenclature
pdb deposition date 2007-12-05
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.30.190 Alpha Beta 2-Layer Sandwich Defensin A-like Defensin A-like 3bk3C00
3BK3C 2MBKA
chains in the Genus database with same CATH superfamily
1PX9A 1YUWA 4H5NA 3KHWA 1SN4A 3KP1A 5BPMA 2N2RA 3L4IA 1JZAA 1ZVGA 2KHOA 3D2EA 4HE7A 1C55A 1POIA 2GL1A 2QWOA 1NRAA 1L4VA 3JXUA 3KOWA 3E7RL 2QW9A 5AQRA 1JKZA 1GPSA 5EVZA 5AQJA 1K8BA 2E3GA 1BUPA 2YIPA 2KJAA 2LJMA 1SN1A 2M8BB 1DKGD 3FZKA 5AQOA 2ASCA 4H5VA 1HJOA 1NGIA 3KOXA 3FZFA 1KAYA 1QQNA 3FZMA 4UAEF 1CN2A 1NGBA 1NGFA 1QQMA 3QFPA 5AQLA 3I33A 2YILA 1HX1A 1PE4A 1TI5A 1BA0A 2QWNA 2YIOA 3L6QA 3LDPA 4AAZA 3QMLA 4HWIA 1FH3A 1NGAA 3KOYA 5BN9A 1I6FA 4AEIA 5F0XA 1OMYA 2G2KA 3HSCA 2I61A 5AQHA 2SN3A 3CQXA 1KV0A 5EX5A 5FPNA 5AQIA 2QWMA 5FPMA 3KC6A 5AQXA 4AB0A 5F1XA 4UADE 5AQPA 5BN8A 5EXWA 1ZUTA 1ATRA 1OZZA 2LT8A 4V1DC 5AQMA 1LQIA 1VNAA 1I6GA 1SEGA 3D2EB 3KP0A 2JDQD 5AQFA 2VY6A 2QWPA 2QWRA 5AQVA 1B7DA 2QXLA 4HHFA 2YEOA 1NGDA 1P00A 3R2VA 4FSVA 1T1TA 3D2FB 3PSMA 2LR3A 1ATSA 3ATUA 2E0HA 1MR4A 1KAZA 1T7BA 3KOZA 3LDOA 2KBKA 1LQHA 1NH5A 2V7ZA 2KSKA 4GNIA 4IO8A 3ATVA 3IUCA 3FE1A 1JXCA 2GMOA 1NGJA 3BK3C 3E7UX 5AQYA 5AQUA 1B3CA 5AQQA 3QFUA 3A8YA 2LY6A 5FPDA 5AQKA 1NGHA 2KPYA 2E8AA 3C7NA 2LY5A 1NRBA 1ICAA 1T7AA 2E88A 1WWNA 1N4NA 2KGQA 5KK4A 1KAXA 1MYNA 1VNBA 2BRZA 2LN8A 3CW4A 1T0ZA 2QWLA 1BMRA 1DJTA 2MBKA 1ZU3A 4KBOA 1UGLA 2BUPA 2YC1C 2B3CA 4UAFE 1HPMA 2KBJA 1NGEA 5AQSA 1AYJA 3AY9A 2E2FA 2LJ7A 1GPTA 5BPNA 3LDLA 3LDNA 1I2VA 5AQGA 1LQQA 2LKBA 1ZYVA 2KBHA 2MZ0A 5EY4A 5AQNA 2D56A 5AQZA 1I2UA 4UJ0A 1QQOA 1WT7A 4KYPA 3SF4D 5CY0A 1CHZA 1NPIA 5BPLA 3FZHA 1DQ7A 5AQTA 3KVGA 2N2QA 5AQWA 2N69A 1BCGA 2MN5A 1ZVEA 2ATBA 1ZFUA 2E3FA 3L56A 1ZYWA 4CQKA 2YBRC 1PTXA 4FL9A 5F2RA 1JZBA 3D2FA 1WMTA 1NE5A 1C56A 2LI7A 3LDQA 4H5RA 2B68A 1SNBA 1BA1A 5FPEA 3C7NB 1NGGA 1NGCA 3M3ZA 2NY8X 2NY9X 4H5WA 2QWQA 3FZLA 1T7EA 2KYQA 2N66A 5AR0A 1AHOA 4H5TA 2A7TA 3GDQA 3QI7A 2K35A 1BRZA 3GL1A 1S3XA 3GKUA 1XRSB 1P0AA 1BK8A
chains in the Genus database with same CATH topology
1YUWA 4H5NA 3KHWA 5BPMA 3L4IA 2KHOA 3D2EA 1POIA 2QWOA 3JXUA 2QW9A 5AQRA 5EVZA 5AQJA 2YIPA 1BUPA 1DKGD 3FZKA 5AQOA 4H5VA 1HJOA 1NGIA 3FZFA 1KAYA 1QQNA 3FZMA 4UAEF 1NGBA 1NGFA 1QQMA 3QFPA 5AQLA 3I33A 2YILA 1HX1A 2QWNA 1BA0A 2YIOA 3L6QA 3LDPA 3QMLA 4HWIA 1NGAA 5BN9A 5F0XA 5AQHA 3HSCA 3CQXA 5EX5A 5FPNA 5FPMA 5AQIA 2QWMA 3KC6A 5AQXA 5F1XA 4UADE 5AQPA 5BN8A 5EXWA 1ATRA 5AQMA 3D2EB 2JDQD 5AQFA 2VY6A 2QWPA 2QWRA 5AQVA 2QXLA 1NGDA 3R2VA 4FSVA 3D2FB 3ATUA 1ATSA 1KAZA 3LDOA 2V7ZA 4GNIA 4IO8A 3ATVA 3IUCA 3FE1A 2GMOA 1NGJA 3BK3C 5AQYA 5AQUA 5AQQA 3QFUA 3A8YA 5FPDA 5AQKA 1NGHA 2E8AA 3C7NA 2E88A 1KAXA 3CW4A 2LN8A 2QWLA 2MBKA 4KBOA 4UAFE 2BUPA 5AQSA 1HPMA 1NGEA 3AY9A 2E2FA 3LDLA 3LDNA 5AQGA 5EY4A 5AQNA 2D56A 5AQZA 1QQOA 3SF4D 5BPLA 3FZHA 5AQTA 3KVGA 5AQWA 2MN5A 3L56A 4FL9A 5F2RA 3D2FA 3LDQA 4H5RA 1BA1A 5FPEA 3C7NB 1NGGA 1NGCA 3M3ZA 4H5WA 2QWQA 3FZLA 5AR0A 4H5TA 3GDQA 3QI7A 2K35A 3GL1A 1S3XA 5BPNA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3BK3 C;  2MBK A; 
#chains in the Genus database with same CATH topology
 1PX9 A;  1YUW A;  4H5N A;  3KHW A;  1SN4 A;  3KP1 A;  5BPM A;  2N2R A;  3L4I A;  1JZA A;  1ZVG A;  2KHO A;  3D2E A;  4HE7 A;  1C55 A;  1POI A;  2GL1 A;  2QWO A;  1NRA A;  1L4V A;  3JXU A;  3KOW A;  3E7R L;  2QW9 A;  5AQR A;  1JKZ A;  1GPS A;  5EVZ A;  5AQJ A;  1K8B A;  2E3G A;  1BUP A;  2YIP A;  2KJA A;  2LJM A;  1SN1 A;  2M8B B;  1DKG D;  3FZK A;  5AQO A;  2ASC A;  4H5V A;  1HJO A;  1NGI A;  3KOX A;  3FZF A;  1KAY A;  1QQN A;  3FZM A;  4UAE F;  1CN2 A;  1NGB A;  1NGF A;  1QQM A;  3QFP A;  5AQL A;  3I33 A;  2YIL A;  1HX1 A;  1PE4 A;  1TI5 A;  1BA0 A;  2QWN A;  2YIO A;  3L6Q A;  3LDP A;  4AAZ A;  3QML A;  4HWI A;  1FH3 A;  1NGA A;  3KOY A;  5BN9 A;  1I6F A;  4AEI A;  5F0X A;  1OMY A;  2G2K A;  3HSC A;  2I61 A;  5AQH A;  2SN3 A;  3CQX A;  1KV0 A;  5EX5 A;  5FPN A;  5AQI A;  2QWM A;  5FPM A;  3KC6 A;  5AQX A;  4AB0 A;  5F1X A;  4UAD E;  5AQP A;  5BN8 A;  5EXW A;  1ZUT A;  1ATR A;  1OZZ A;  2LT8 A;  4V1D C;  5AQM A;  1LQI A;  1VNA A;  1I6G A;  1SEG A;  3D2E B;  3KP0 A;  2JDQ D;  5AQF A;  2VY6 A;  2QWP A;  2QWR A;  5AQV A;  1B7D A;  2QXL A;  4HHF A;  2YEO A;  1NGD A;  1P00 A;  3R2V A;  4FSV A;  1T1T A;  3D2F B;  3PSM A;  2LR3 A;  1ATS A;  3ATU A;  2E0H A;  1MR4 A;  1KAZ A;  1T7B A;  3KOZ A;  3LDO A;  2KBK A;  1LQH A;  1NH5 A;  2V7Z A;  2KSK A;  4GNI A;  4IO8 A;  3ATV A;  3IUC A;  3FE1 A;  1JXC A;  2GMO A;  1NGJ A;  3BK3 C;  3E7U X;  5AQY A;  5AQU A;  1B3C A;  5AQQ A;  3QFU A;  3A8Y A;  2LY6 A;  5FPD A;  5AQK A;  1NGH A;  2KPY A;  2E8A A;  3C7N A;  2LY5 A;  1NRB A;  1ICA A;  1T7A A;  2E88 A;  1WWN A;  1N4N A;  2KGQ A;  5KK4 A;  1KAX A;  1MYN A;  1VNB A;  2BRZ A;  2LN8 A;  3CW4 A;  1T0Z A;  2QWL A;  1BMR A;  1DJT A;  2MBK A;  1ZU3 A;  4KBO A;  1UGL A;  2BUP A;  2YC1 C;  2B3C A;  4UAF E;  1HPM A;  2KBJ A;  1NGE A;  5AQS A;  1AYJ A;  3AY9 A;  2E2F A;  2LJ7 A;  1GPT A;  5BPN A;  3LDL A;  3LDN A;  1I2V A;  5AQG A;  1LQQ A;  2LKB A;  1ZYV A;  2KBH A;  2MZ0 A;  5EY4 A;  5AQN A;  2D56 A;  5AQZ A;  1I2U A;  4UJ0 A;  1QQO A;  1WT7 A;  4KYP A;  3SF4 D;  5CY0 A;  1CHZ A;  1NPI A;  5BPL A;  3FZH A;  1DQ7 A;  5AQT A;  3KVG A;  2N2Q A;  5AQW A;  2N69 A;  1BCG A;  2MN5 A;  1ZVE A;  2ATB A;  1ZFU A;  2E3F A;  3L56 A;  1ZYW A;  4CQK A;  2YBR C;  1PTX A;  4FL9 A;  5F2R A;  1JZB A;  3D2F A;  1WMT A;  1NE5 A;  1C56 A;  2LI7 A;  3LDQ A;  4H5R A;  2B68 A;  1SNB A;  1BA1 A;  5FPE A;  3C7N B;  1NGG A;  1NGC A;  3M3Z A;  2NY8 X;  2NY9 X;  4H5W A;  2QWQ A;  3FZL A;  1T7E A;  2KYQ A;  2N66 A;  5AR0 A;  1AHO A;  4H5T A;  2A7T A;  3GDQ A;  3QI7 A;  2K35 A;  1BRZ A;  3GL1 A;  1S3X A;  3GKU A;  1XRS B;  1P0A A;  1BK8 A; 
#chains in the Genus database with same CATH homology
 1YUW A;  4H5N A;  3KHW A;  5BPM A;  3L4I A;  2KHO A;  3D2E A;  1POI A;  2QWO A;  3JXU A;  2QW9 A;  5AQR A;  5EVZ A;  5AQJ A;  2YIP A;  1BUP A;  1DKG D;  3FZK A;  5AQO A;  4H5V A;  1HJO A;  1NGI A;  3FZF A;  1KAY A;  1QQN A;  3FZM A;  4UAE F;  1NGB A;  1NGF A;  1QQM A;  3QFP A;  5AQL A;  3I33 A;  2YIL A;  1HX1 A;  2QWN A;  1BA0 A;  2YIO A;  3L6Q A;  3LDP A;  3QML A;  4HWI A;  1NGA A;  5BN9 A;  5F0X A;  5AQH A;  3HSC A;  3CQX A;  5EX5 A;  5FPN A;  5FPM A;  5AQI A;  2QWM A;  3KC6 A;  5AQX A;  5F1X A;  4UAD E;  5AQP A;  5BN8 A;  5EXW A;  1ATR A;  5AQM A;  3D2E B;  2JDQ D;  5AQF A;  2VY6 A;  2QWP A;  2QWR A;  5AQV A;  2QXL A;  1NGD A;  3R2V A;  4FSV A;  3D2F B;  3ATU A;  1ATS A;  1KAZ A;  3LDO A;  2V7Z A;  4GNI A;  4IO8 A;  3ATV A;  3IUC A;  3FE1 A;  2GMO A;  1NGJ A;  3BK3 C;  5AQY A;  5AQU A;  5AQQ A;  3QFU A;  3A8Y A;  5FPD A;  5AQK A;  1NGH A;  2E8A A;  3C7N A;  2E88 A;  1KAX A;  3CW4 A;  2LN8 A;  2QWL A;  2MBK A;  4KBO A;  4UAF E;  2BUP A;  5AQS A;  1HPM A;  1NGE A;  3AY9 A;  2E2F A;  3LDL A;  3LDN A;  5AQG A;  5EY4 A;  5AQN A;  2D56 A;  5AQZ A;  1QQO A;  3SF4 D;  5BPL A;  3FZH A;  5AQT A;  3KVG A;  5AQW A;  2MN5 A;  3L56 A;  4FL9 A;  5F2R A;  3D2F A;  3LDQ A;  4H5R A;  1BA1 A;  5FPE A;  3C7N B;  1NGG A;  1NGC A;  3M3Z A;  4H5W A;  2QWQ A;  3FZL A;  5AR0 A;  4H5T A;  3GDQ A;  3QI7 A;  2K35 A;  3GL1 A;  1S3X A;  5BPN A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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