3CW4A

Large c-terminal domain of influenza a virus rna-dependent polymerase pb2
Total Genus 55
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
55
sequence length
208
structure length
208
Chain Sequence
MMWEINGPESVLVNTYQWIIRNWETVKIQWSQNPTMLYNKMEFEPFQSLVPKAIRGQYSGFVRTLFQQMRDVLGTFDTAQIIKLLPFAAAPPKQSRMQFSSFTVNVRGSGMRILVRGNSPVFNYNKATKRLTVLGKDAGTLTEDPDEGTAGVESAVLRGFLILGKEDKRYGPALSINELSNLAKGEKANVLIGQGDVVLVMKRKRDSS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of the influenza A virus RNA polymerase PB2 RNA-binding domain containing the pathogenicity-determinant lysine 627 residue
pubmed doi rcsb
molecule tags Transferase
source organism Influenza a virus
molecule keywords Polymerase basic protein 2
total genus 55
structure length 208
sequence length 208
ec nomenclature ec 2.7.-.-:
pdb deposition date 2008-04-21
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.30.90 Alpha Beta 2-Layer Sandwich Defensin A-like Defensin A-like 3cw4A02
4UAFE 4UAEF 4UADE 3R2VA 3CW4A 3KHWA 2GMOA 3L56A 3KC6A 2VY6A 2JDQD
chains in the Genus database with same CATH superfamily
3QI7A 1PX9A 1QQMA 1NGCA 1NGFA 1KAXA 4H5TA 2E3GA 2N2QA 3KP1A 4UJ0A 2E88A 3KOXA 1ZVGA 1WT7A 5AQOA 5AQZA 1B3CA 1P00A 1SEGA 2KHOA 2B3CA 1T7EA 3IUCA 5AQGA 1MYNA 1NGHA 2YILA 5EVZA 2LKBA 5FPEA 5CY0A 1FH3A 1NGIA 5AQMA 1I6FA 3L56A 1AYJA 3KOWA 1I6GA 4HE7A 5AQLA 1GPTA 1JZAA 2E2FA 2LI7A 2YBRC 3JXUA 2YIOA 2LY6A 3KHWA 3LDNA 3R2VA 4AB0A 1NGEA 2GMOA 3D2FB 1N4NA 1QQOA 1WWNA 2LR3A 2VY6A 5F1XA 1BUPA 4AAZA 4KBOA 2QWPA 1PTXA 1LQQA 1ZYWA 1T7BA 2BUPA 2N66A 2QXLA 3L4IA 4UADE 1CHZA 5AQXA 1OMYA 2YC1C 3ATVA 2LN8A 5AQQA 1ICAA 1L4VA 3CW4A 1ATRA 3D2EB 2NY8X 1HJOA 1ZVEA 2V7ZA 4H5RA 1I2UA 1K8BA 3SF4D 1HPMA 1ZU3A 2LJ7A 2KYQA 5AQIA 5AQSA 2ASCA 3AY9A 2M8BB 5FPNA 4GNIA 3QMLA 5FPMA 2GL1A 2N2RA 4AEIA 5KK4A 1KAZA 1NGGA 3D2FA 2MBKA 4FSVA 5AQNA 2E0HA 1C55A 1BRZA 5AQUA 1AHOA 3GL1A 4V1DC 5BPMA 1XRSB 1DQ7A 5BPLA 3KOYA 1PE4A 2QWMA 5AQFA 3QFUA 5BPNA 5AQHA 1NGAA 5BN8A 2KJAA 5EX5A 5AQWA 5BN9A 1S3XA 2D56A 4UAEF 1BMRA 3KVGA 3L6QA 1P0AA 3LDOA 1VNBA 5AQVA 1LQIA 5EY4A 3D2EA 2KGQA 1OZZA 3LDPA 1BA1A 4H5NA 4H5WA 1ZYVA 5AQPA 1BCGA 3FZMA 1GPSA 5AQJA 3KC6A 1BA0A 1JXCA 1B7DA 2KSKA 2QWLA 1HX1A 1KAYA 1NRBA 2KPYA 1T1TA 2QWRA 4IO8A 2MN5A 3FZKA 3KOZA 5EXWA 1NH5A 1VNAA 1SN1A 2NY9X 3E7UX 2QWQA 3LDQA 3CQXA 1CN2A 3PSMA 4HHFA 5FPDA 1TI5A 3KP0A 2ATBA 1BK8A 3FE1A 2K35A 1SNBA 2YEOA 3C7NB 1WMTA 1NPIA 5F2RA 1JZBA 4H5VA 2G2KA 3BK3C 2LJMA 3HSCA 2QW9A 3ATUA 1C56A 5AQYA 1T0ZA 3I33A 1ZUTA 5F0XA 5AQTA 1QQNA 2E8AA 2SN3A 2KBKA 2QWOA 1ZFUA 4KYPA 2YIPA 1KV0A 1I2VA 3FZFA 4FL9A 1DKGD 2A7TA 1T7AA 1MR4A 1POIA 5AQKA 5AR0A 2MZ0A 2N69A 2QWNA 3GKUA 3FZHA 1NGBA 3LDLA 3M3ZA 4UAFE 1ATSA 3FZLA 2KBJA 4HWIA 3C7NA 2LT8A 1NRAA 1JKZA 2B68A 1SN4A 1NGDA 1UGLA 1LQHA 1NGJA 2LY5A 3E7RL 3GDQA 2BRZA 4CQKA 1YUWA 1DJTA 5AQRA 2I61A 3QFPA 3A8YA 2JDQD 2E3FA 2KBHA 1NE5A
chains in the Genus database with same CATH topology
3QI7A 1QQMA 1NGCA 1NGFA 1KAXA 4H5TA 2E88A 5AQOA 5AQZA 2KHOA 5AQGA 3IUCA 1NGHA 2YILA 5EVZA 5FPEA 1NGIA 5AQMA 3L56A 5AQLA 2E2FA 3R2VA 3JXUA 3LDNA 2YIOA 3KHWA 1NGEA 3D2FB 2GMOA 1QQOA 2VY6A 5F1XA 1BUPA 4KBOA 2QWPA 2BUPA 2QXLA 4UADE 3L4IA 5AQXA 3ATVA 2LN8A 5AQQA 3CW4A 1ATRA 3D2EB 1HJOA 2V7ZA 4H5RA 3SF4D 1HPMA 5AQIA 5AQSA 3AY9A 5FPNA 4GNIA 3QMLA 5FPMA 1KAZA 1NGGA 3D2FA 2MBKA 4FSVA 5AQNA 5AQUA 3GL1A 5BPMA 5BPLA 2QWMA 5AQFA 3QFUA 5BPNA 5AQHA 1NGAA 5BN8A 5EX5A 5AQWA 5BN9A 1S3XA 2D56A 4UAEF 3KVGA 3L6QA 3LDOA 5AQVA 5EY4A 3D2EA 3LDPA 1BA1A 4H5NA 4H5WA 5AQPA 3FZMA 5AQJA 3KC6A 1BA0A 2QWLA 1HX1A 1KAYA 4IO8A 2QWRA 2MN5A 3FZKA 5EXWA 5F0XA 3LDQA 2QWQA 3CQXA 5FPDA 3FE1A 2K35A 5F2RA 3C7NB 4H5VA 3BK3C 3HSCA 2QW9A 3ATUA 5AQYA 3I33A 5AQTA 1QQNA 2E8AA 2QWOA 2YIPA 3FZFA 4FL9A 1DKGD 1POIA 5AQKA 5AR0A 2QWNA 3FZHA 1NGBA 3LDLA 3M3ZA 4UAFE 1ATSA 3FZLA 4HWIA 3C7NA 1NGDA 1NGJA 3GDQA 1YUWA 5AQRA 3QFPA 3A8YA 2JDQD
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4UAF E;  4UAE F;  4UAD E;  3R2V A;  3CW4 A;  3KHW A;  2GMO A;  3L56 A;  3KC6 A;  2VY6 A;  2JDQ D; 
#chains in the Genus database with same CATH topology
 3QI7 A;  1PX9 A;  1QQM A;  1NGC A;  1NGF A;  1KAX A;  4H5T A;  2E3G A;  2N2Q A;  3KP1 A;  4UJ0 A;  2E88 A;  3KOX A;  1ZVG A;  1WT7 A;  5AQO A;  5AQZ A;  1B3C A;  1P00 A;  1SEG A;  2KHO A;  2B3C A;  1T7E A;  3IUC A;  5AQG A;  1MYN A;  1NGH A;  2YIL A;  5EVZ A;  2LKB A;  5FPE A;  5CY0 A;  1FH3 A;  1NGI A;  5AQM A;  1I6F A;  3L56 A;  1AYJ A;  3KOW A;  1I6G A;  4HE7 A;  5AQL A;  1GPT A;  1JZA A;  2E2F A;  2LI7 A;  2YBR C;  3JXU A;  2YIO A;  2LY6 A;  3KHW A;  3LDN A;  3R2V A;  4AB0 A;  1NGE A;  2GMO A;  3D2F B;  1N4N A;  1QQO A;  1WWN A;  2LR3 A;  2VY6 A;  5F1X A;  1BUP A;  4AAZ A;  4KBO A;  2QWP A;  1PTX A;  1LQQ A;  1ZYW A;  1T7B A;  2BUP A;  2N66 A;  2QXL A;  3L4I A;  4UAD E;  1CHZ A;  5AQX A;  1OMY A;  2YC1 C;  3ATV A;  2LN8 A;  5AQQ A;  1ICA A;  1L4V A;  3CW4 A;  1ATR A;  3D2E B;  2NY8 X;  1HJO A;  1ZVE A;  2V7Z A;  4H5R A;  1I2U A;  1K8B A;  3SF4 D;  1HPM A;  1ZU3 A;  2LJ7 A;  2KYQ A;  5AQI A;  5AQS A;  2ASC A;  3AY9 A;  2M8B B;  5FPN A;  4GNI A;  3QML A;  5FPM A;  2GL1 A;  2N2R A;  4AEI A;  5KK4 A;  1KAZ A;  1NGG A;  3D2F A;  2MBK A;  4FSV A;  5AQN A;  2E0H A;  1C55 A;  1BRZ A;  5AQU A;  1AHO A;  3GL1 A;  4V1D C;  5BPM A;  1XRS B;  1DQ7 A;  5BPL A;  3KOY A;  1PE4 A;  2QWM A;  5AQF A;  3QFU A;  5BPN A;  5AQH A;  1NGA A;  5BN8 A;  2KJA A;  5EX5 A;  5AQW A;  5BN9 A;  1S3X A;  2D56 A;  4UAE F;  1BMR A;  3KVG A;  3L6Q A;  1P0A A;  3LDO A;  1VNB A;  5AQV A;  1LQI A;  5EY4 A;  3D2E A;  2KGQ A;  1OZZ A;  3LDP A;  1BA1 A;  4H5N A;  4H5W A;  1ZYV A;  5AQP A;  1BCG A;  3FZM A;  1GPS A;  5AQJ A;  3KC6 A;  1BA0 A;  1JXC A;  1B7D A;  2KSK A;  2QWL A;  1HX1 A;  1KAY A;  1NRB A;  2KPY A;  1T1T A;  2QWR A;  4IO8 A;  2MN5 A;  3FZK A;  3KOZ A;  5EXW A;  1NH5 A;  1VNA A;  1SN1 A;  2NY9 X;  3E7U X;  2QWQ A;  3LDQ A;  3CQX A;  1CN2 A;  3PSM A;  4HHF A;  5FPD A;  1TI5 A;  3KP0 A;  2ATB A;  1BK8 A;  3FE1 A;  2K35 A;  1SNB A;  2YEO A;  3C7N B;  1WMT A;  1NPI A;  5F2R A;  1JZB A;  4H5V A;  2G2K A;  3BK3 C;  2LJM A;  3HSC A;  2QW9 A;  3ATU A;  1C56 A;  5AQY A;  1T0Z A;  3I33 A;  1ZUT A;  5F0X A;  5AQT A;  1QQN A;  2E8A A;  2SN3 A;  2KBK A;  2QWO A;  1ZFU A;  4KYP A;  2YIP A;  1KV0 A;  1I2V A;  3FZF A;  4FL9 A;  1DKG D;  2A7T A;  1T7A A;  1MR4 A;  1POI A;  5AQK A;  5AR0 A;  2MZ0 A;  2N69 A;  2QWN A;  3GKU A;  3FZH A;  1NGB A;  3LDL A;  3M3Z A;  4UAF E;  1ATS A;  3FZL A;  2KBJ A;  4HWI A;  3C7N A;  2LT8 A;  1NRA A;  1JKZ A;  2B68 A;  1SN4 A;  1NGD A;  1UGL A;  1LQH A;  1NGJ A;  2LY5 A;  3E7R L;  3GDQ A;  2BRZ A;  4CQK A;  1YUW A;  1DJT A;  5AQR A;  2I61 A;  3QFP A;  3A8Y A;  2JDQ D;  2E3F A;  2KBH A;  1NE5 A; 
#chains in the Genus database with same CATH homology
 3QI7 A;  1QQM A;  1NGC A;  1NGF A;  1KAX A;  4H5T A;  2E88 A;  5AQO A;  5AQZ A;  2KHO A;  5AQG A;  3IUC A;  1NGH A;  2YIL A;  5EVZ A;  5FPE A;  1NGI A;  5AQM A;  3L56 A;  5AQL A;  2E2F A;  3R2V A;  3JXU A;  3LDN A;  2YIO A;  3KHW A;  1NGE A;  3D2F B;  2GMO A;  1QQO A;  2VY6 A;  5F1X A;  1BUP A;  4KBO A;  2QWP A;  2BUP A;  2QXL A;  4UAD E;  3L4I A;  5AQX A;  3ATV A;  2LN8 A;  5AQQ A;  3CW4 A;  1ATR A;  3D2E B;  1HJO A;  2V7Z A;  4H5R A;  3SF4 D;  1HPM A;  5AQI A;  5AQS A;  3AY9 A;  5FPN A;  4GNI A;  3QML A;  5FPM A;  1KAZ A;  1NGG A;  3D2F A;  2MBK A;  4FSV A;  5AQN A;  5AQU A;  3GL1 A;  5BPM A;  5BPL A;  2QWM A;  5AQF A;  3QFU A;  5BPN A;  5AQH A;  1NGA A;  5BN8 A;  5EX5 A;  5AQW A;  5BN9 A;  1S3X A;  2D56 A;  4UAE F;  3KVG A;  3L6Q A;  3LDO A;  5AQV A;  5EY4 A;  3D2E A;  3LDP A;  1BA1 A;  4H5N A;  4H5W A;  5AQP A;  3FZM A;  5AQJ A;  3KC6 A;  1BA0 A;  2QWL A;  1HX1 A;  1KAY A;  4IO8 A;  2QWR A;  2MN5 A;  3FZK A;  5EXW A;  5F0X A;  3LDQ A;  2QWQ A;  3CQX A;  5FPD A;  3FE1 A;  2K35 A;  5F2R A;  3C7N B;  4H5V A;  3BK3 C;  3HSC A;  2QW9 A;  3ATU A;  5AQY A;  3I33 A;  5AQT A;  1QQN A;  2E8A A;  2QWO A;  2YIP A;  3FZF A;  4FL9 A;  1DKG D;  1POI A;  5AQK A;  5AR0 A;  2QWN A;  3FZH A;  1NGB A;  3LDL A;  3M3Z A;  4UAF E;  1ATS A;  3FZL A;  4HWI A;  3C7N A;  1NGD A;  1NGJ A;  3GDQ A;  1YUW A;  5AQR A;  3QFP A;  3A8Y A;  2JDQ D; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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