3CW4A

Large c-terminal domain of influenza a virus rna-dependent polymerase pb2
Total Genus 55
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
55
sequence length
208
structure length
208
Chain Sequence
MMWEINGPESVLVNTYQWIIRNWETVKIQWSQNPTMLYNKMEFEPFQSLVPKAIRGQYSGFVRTLFQQMRDVLGTFDTAQIIKLLPFAAAPPKQSRMQFSSFTVNVRGSGMRILVRGNSPVFNYNKATKRLTVLGKDAGTLTEDPDEGTAGVESAVLRGFLILGKEDKRYGPALSINELSNLAKGEKANVLIGQGDVVLVMKRKRDSS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of the influenza A virus RNA polymerase PB2 RNA-binding domain containing the pathogenicity-determinant lysine 627 residue
pubmed doi rcsb
molecule tags Transferase
source organism Influenza a virus
molecule keywords Polymerase basic protein 2
total genus 55
structure length 208
sequence length 208
ec nomenclature ec 2.7.-.-:
pdb deposition date 2008-04-21
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.30.90 Alpha Beta 2-Layer Sandwich Defensin A-like Defensin A-like 3cw4A02
3KC6A 3KHWA 2JDQD 3R2VA 2GMOA 4UAFE 3L56A 3CW4A 2VY6A 4UAEF 4UADE
chains in the Genus database with same CATH superfamily
1NGDA 1SN4A 2B3CA 1I6GA 1NRAA 1QQNA 1NGFA 3CW4A 5AQLA 5F1XA 5KK4A 1WT7A 1XRSB 3ATVA 2MZ0A 2LKBA 3JXUA 3KOXA 1JZAA 3A8YA 3R2VA 1SEGA 3I33A 2N2QA 3CQXA 1LQQA 3IUCA 1BCGA 1KAYA 1S3XA 1T0ZA 2NY8X 4H5NA 1QQMA 1SN1A 2E88A 2LY6A 4HHFA 1AYJA 1B7DA 2QWQA 3C7NB 2D56A 5EVZA 1N4NA 4AB0A 2B68A 2KHOA 3HSCA 5AQRA 2NY9X 1HJOA 1KAXA 3FE1A 2M8BB 3L4IA 2N69A 3E7UX 5BPNA 3C7NA 1NGHA 3SF4D 1CN2A 3FZFA 2LR3A 1NGBA 2KPYA 2LJ7A 3KHWA 2KGQA 5BN9A 1GPTA 2KJAA 3D2FA 2KBHA 3QI7A 1HPMA 1P00A 2KBJA 2YC1C 1BA1A 5AQHA 5AQMA 2I61A 3KOYA 2ASCA 1BA0A 4AAZA 1JXCA 1NGJA 1ZVEA 2BUPA 3L56A 2QW9A 2V7ZA 3KOZA 1ZUTA 5AQOA 4CQKA 4H5VA 2LN8A 2QWRA 2YILA 4AEIA 3QFUA 5EXWA 5AQFA 2JDQD 1ATRA 1ZFUA 2KYQA 1VNBA 2YEOA 2MBKA 3KP1A 4V1DC 1NE5A 1C55A 2LI7A 2ATBA 2LT8A 1P0AA 2E2FA 3LDLA 3KOWA 1NH5A 1PX9A 2GMOA 1UGLA 2N2RA 1YUWA 1OZZA 3D2FB 3L6QA 3LDQA 1WMTA 4H5WA 1MR4A 5AQPA 5FPMA 3M3ZA 4KYPA 4HE7A 2YIOA 5AQJA 4FL9A 3GKUA 5F0XA 5FPNA 2LY5A 1ZYVA 3LDPA 5F2RA 5CY0A 1PTXA 5AQTA 1TI5A 4UADE 1AHOA 1NPIA 3FZMA 3KC6A 1ICAA 1BUPA 1NGGA 2A7TA 5AQGA 1T7EA 5AQXA 1JZBA 2E3FA 2QWLA 4HWIA 1LQHA 5EY4A 4H5RA 1VNAA 1BK8A 3KP0A 5AQIA 1DJTA 3GL1A 1WWNA 2E0HA 2SN3A 2G2KA 1ZYWA 3E7RL 5AQUA 1B3CA 2QXLA 1T7BA 3BK3C 5AQWA 2KSKA 3FZLA 3ATUA 1POIA 3GDQA 2VY6A 1QQOA 2KBKA 2QWOA 5BN8A 1MYNA 5AQYA 1LQIA 2GL1A 5AQVA 5EX5A 3QMLA 5AQZA 1KAZA 1PE4A 1C56A 3PSMA 1NGIA 1T7AA 2E8AA 2K35A 2QWMA 3LDNA 3QFPA 4GNIA 1KV0A 1NRBA 3D2EB 3FZKA 5AQKA 1NGAA 4UAFE 1BMRA 3LDOA 4KBOA 3FZHA 5AQNA 5BPLA 1I2UA 1DKGD 2QWPA 5FPDA 5AQSA 1SNBA 5BPMA 2YBRC 1BRZA 3D2EA 1JKZA 1I2VA 1FH3A 2E3GA 3KVGA 4FSVA 2QWNA 1ZU3A 3AY9A 1DQ7A 1OMYA 1ZVGA 2YIPA 5AQQA 1CHZA 1GPSA 5FPEA 1HX1A 1NGCA 5AR0A 2MN5A 1NGEA 2BRZA 2N66A 2LJMA 4UJ0A 1T1TA 1ATSA 1I6FA 1K8BA 1L4VA 4IO8A 4UAEF 4H5TA
chains in the Genus database with same CATH topology
1NGDA 1QQNA 5AQLA 1NGFA 3CW4A 5F1XA 3ATVA 3JXUA 3A8YA 3R2VA 3I33A 3CQXA 3IUCA 1KAYA 1S3XA 4H5NA 1QQMA 2E88A 2QWQA 3C7NB 2D56A 5EVZA 2KHOA 3HSCA 5AQRA 1HJOA 1KAXA 3FE1A 3L4IA 5BPNA 3C7NA 1NGHA 3SF4D 3FZFA 1NGBA 3KHWA 5BN9A 3D2FA 3QI7A 1HPMA 5AQHA 1BA1A 5AQMA 1BA0A 1NGJA 2BUPA 3L56A 2QW9A 2V7ZA 5AQOA 4H5VA 2LN8A 2QWRA 2YILA 3QFUA 5EXWA 5AQFA 2JDQD 1ATRA 2MBKA 3LDLA 2E2FA 2GMOA 1YUWA 3D2FB 3L6QA 3LDQA 5AQPA 4H5WA 5FPMA 3M3ZA 5AQJA 2YIOA 4FL9A 5F0XA 5FPNA 3LDPA 5F2RA 5AQTA 4UADE 3KC6A 3FZMA 1BUPA 1NGGA 5AQGA 5AQXA 2QWLA 4HWIA 5EY4A 4H5RA 5AQIA 3GL1A 5AQUA 2QXLA 3BK3C 5AQWA 3FZLA 3ATUA 1POIA 3GDQA 2VY6A 1QQOA 2QWOA 5BN8A 5AQYA 5AQZA 5AQVA 5EX5A 3QMLA 1KAZA 1NGIA 2E8AA 2K35A 2QWMA 3LDNA 3QFPA 4GNIA 3D2EB 3FZKA 5AQKA 1NGAA 4UAFE 3LDOA 4KBOA 3FZHA 5AQNA 5BPLA 1DKGD 2QWPA 5FPDA 5AQSA 5BPMA 3D2EA 3KVGA 4FSVA 2QWNA 3AY9A 2YIPA 5AQQA 5FPEA 1HX1A 1NGCA 5AR0A 2MN5A 1NGEA 1ATSA 4IO8A 4UAEF 4H5TA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3KC6 A;  3KHW A;  2JDQ D;  3R2V A;  2GMO A;  4UAF E;  3L56 A;  3CW4 A;  2VY6 A;  4UAE F;  4UAD E; 
#chains in the Genus database with same CATH topology
 1NGD A;  1SN4 A;  2B3C A;  1I6G A;  1NRA A;  1QQN A;  1NGF A;  3CW4 A;  5AQL A;  5F1X A;  5KK4 A;  1WT7 A;  1XRS B;  3ATV A;  2MZ0 A;  2LKB A;  3JXU A;  3KOX A;  1JZA A;  3A8Y A;  3R2V A;  1SEG A;  3I33 A;  2N2Q A;  3CQX A;  1LQQ A;  3IUC A;  1BCG A;  1KAY A;  1S3X A;  1T0Z A;  2NY8 X;  4H5N A;  1QQM A;  1SN1 A;  2E88 A;  2LY6 A;  4HHF A;  1AYJ A;  1B7D A;  2QWQ A;  3C7N B;  2D56 A;  5EVZ A;  1N4N A;  4AB0 A;  2B68 A;  2KHO A;  3HSC A;  5AQR A;  2NY9 X;  1HJO A;  1KAX A;  3FE1 A;  2M8B B;  3L4I A;  2N69 A;  3E7U X;  5BPN A;  3C7N A;  1NGH A;  3SF4 D;  1CN2 A;  3FZF A;  2LR3 A;  1NGB A;  2KPY A;  2LJ7 A;  3KHW A;  2KGQ A;  5BN9 A;  1GPT A;  2KJA A;  3D2F A;  2KBH A;  3QI7 A;  1HPM A;  1P00 A;  2KBJ A;  2YC1 C;  1BA1 A;  5AQH A;  5AQM A;  2I61 A;  3KOY A;  2ASC A;  1BA0 A;  4AAZ A;  1JXC A;  1NGJ A;  1ZVE A;  2BUP A;  3L56 A;  2QW9 A;  2V7Z A;  3KOZ A;  1ZUT A;  5AQO A;  4CQK A;  4H5V A;  2LN8 A;  2QWR A;  2YIL A;  4AEI A;  3QFU A;  5EXW A;  5AQF A;  2JDQ D;  1ATR A;  1ZFU A;  2KYQ A;  1VNB A;  2YEO A;  2MBK A;  3KP1 A;  4V1D C;  1NE5 A;  1C55 A;  2LI7 A;  2ATB A;  2LT8 A;  1P0A A;  2E2F A;  3LDL A;  3KOW A;  1NH5 A;  1PX9 A;  2GMO A;  1UGL A;  2N2R A;  1YUW A;  1OZZ A;  3D2F B;  3L6Q A;  3LDQ A;  1WMT A;  4H5W A;  1MR4 A;  5AQP A;  5FPM A;  3M3Z A;  4KYP A;  4HE7 A;  2YIO A;  5AQJ A;  4FL9 A;  3GKU A;  5F0X A;  5FPN A;  2LY5 A;  1ZYV A;  3LDP A;  5F2R A;  5CY0 A;  1PTX A;  5AQT A;  1TI5 A;  4UAD E;  1AHO A;  1NPI A;  3FZM A;  3KC6 A;  1ICA A;  1BUP A;  1NGG A;  2A7T A;  5AQG A;  1T7E A;  5AQX A;  1JZB A;  2E3F A;  2QWL A;  4HWI A;  1LQH A;  5EY4 A;  4H5R A;  1VNA A;  1BK8 A;  3KP0 A;  5AQI A;  1DJT A;  3GL1 A;  1WWN A;  2E0H A;  2SN3 A;  2G2K A;  1ZYW A;  3E7R L;  5AQU A;  1B3C A;  2QXL A;  1T7B A;  3BK3 C;  5AQW A;  2KSK A;  3FZL A;  3ATU A;  1POI A;  3GDQ A;  2VY6 A;  1QQO A;  2KBK A;  2QWO A;  5BN8 A;  1MYN A;  5AQY A;  1LQI A;  2GL1 A;  5AQV A;  5EX5 A;  3QML A;  5AQZ A;  1KAZ A;  1PE4 A;  1C56 A;  3PSM A;  1NGI A;  1T7A A;  2E8A A;  2K35 A;  2QWM A;  3LDN A;  3QFP A;  4GNI A;  1KV0 A;  1NRB A;  3D2E B;  3FZK A;  5AQK A;  1NGA A;  4UAF E;  1BMR A;  3LDO A;  4KBO A;  3FZH A;  5AQN A;  5BPL A;  1I2U A;  1DKG D;  2QWP A;  5FPD A;  5AQS A;  1SNB A;  5BPM A;  2YBR C;  1BRZ A;  3D2E A;  1JKZ A;  1I2V A;  1FH3 A;  2E3G A;  3KVG A;  4FSV A;  2QWN A;  1ZU3 A;  3AY9 A;  1DQ7 A;  1OMY A;  1ZVG A;  2YIP A;  5AQQ A;  1CHZ A;  1GPS A;  5FPE A;  1HX1 A;  1NGC A;  5AR0 A;  2MN5 A;  1NGE A;  2BRZ A;  2N66 A;  2LJM A;  4UJ0 A;  1T1T A;  1ATS A;  1I6F A;  1K8B A;  1L4V A;  4IO8 A;  4UAE F;  4H5T A; 
#chains in the Genus database with same CATH homology
 1NGD A;  1QQN A;  5AQL A;  1NGF A;  3CW4 A;  5F1X A;  3ATV A;  3JXU A;  3A8Y A;  3R2V A;  3I33 A;  3CQX A;  3IUC A;  1KAY A;  1S3X A;  4H5N A;  1QQM A;  2E88 A;  2QWQ A;  3C7N B;  2D56 A;  5EVZ A;  2KHO A;  3HSC A;  5AQR A;  1HJO A;  1KAX A;  3FE1 A;  3L4I A;  5BPN A;  3C7N A;  1NGH A;  3SF4 D;  3FZF A;  1NGB A;  3KHW A;  5BN9 A;  3D2F A;  3QI7 A;  1HPM A;  5AQH A;  1BA1 A;  5AQM A;  1BA0 A;  1NGJ A;  2BUP A;  3L56 A;  2QW9 A;  2V7Z A;  5AQO A;  4H5V A;  2LN8 A;  2QWR A;  2YIL A;  3QFU A;  5EXW A;  5AQF A;  2JDQ D;  1ATR A;  2MBK A;  3LDL A;  2E2F A;  2GMO A;  1YUW A;  3D2F B;  3L6Q A;  3LDQ A;  5AQP A;  4H5W A;  5FPM A;  3M3Z A;  5AQJ A;  2YIO A;  4FL9 A;  5F0X A;  5FPN A;  3LDP A;  5F2R A;  5AQT A;  4UAD E;  3KC6 A;  3FZM A;  1BUP A;  1NGG A;  5AQG A;  5AQX A;  2QWL A;  4HWI A;  5EY4 A;  4H5R A;  5AQI A;  3GL1 A;  5AQU A;  2QXL A;  3BK3 C;  5AQW A;  3FZL A;  3ATU A;  1POI A;  3GDQ A;  2VY6 A;  1QQO A;  2QWO A;  5BN8 A;  5AQY A;  5AQZ A;  5AQV A;  5EX5 A;  3QML A;  1KAZ A;  1NGI A;  2E8A A;  2K35 A;  2QWM A;  3LDN A;  3QFP A;  4GNI A;  3D2E B;  3FZK A;  5AQK A;  1NGA A;  4UAF E;  3LDO A;  4KBO A;  3FZH A;  5AQN A;  5BPL A;  1DKG D;  2QWP A;  5FPD A;  5AQS A;  5BPM A;  3D2E A;  3KVG A;  4FSV A;  2QWN A;  3AY9 A;  2YIP A;  5AQQ A;  5FPE A;  1HX1 A;  1NGC A;  5AR0 A;  2MN5 A;  1NGE A;  1ATS A;  4IO8 A;  4UAE F;  4H5T A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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