3CW4A

Large c-terminal domain of influenza a virus rna-dependent polymerase pb2
Total Genus 55
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
55
sequence length
208
structure length
208
Chain Sequence
MMWEINGPESVLVNTYQWIIRNWETVKIQWSQNPTMLYNKMEFEPFQSLVPKAIRGQYSGFVRTLFQQMRDVLGTFDTAQIIKLLPFAAAPPKQSRMQFSSFTVNVRGSGMRILVRGNSPVFNYNKATKRLTVLGKDAGTLTEDPDEGTAGVESAVLRGFLILGKEDKRYGPALSINELSNLAKGEKANVLIGQGDVVLVMKRKRDSS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of the influenza A virus RNA polymerase PB2 RNA-binding domain containing the pathogenicity-determinant lysine 627 residue
pubmed doi rcsb
molecule tags Transferase
source organism Influenza a virus
molecule keywords Polymerase basic protein 2
total genus 55
structure length 208
sequence length 208
ec nomenclature ec 2.7.-.-:
pdb deposition date 2008-04-21
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.30.90 Alpha Beta 2-Layer Sandwich Defensin A-like Defensin A-like 3cw4A02
3L56A 3CW4A 3KHWA 2JDQD 2GMOA 4UAEF 4UAFE 4UADE 3KC6A 2VY6A 3R2VA
chains in the Genus database with same CATH superfamily
3ATUA 3L56A 1I6GA 2G2KA 4H5TA 4HWIA 3KP1A 3LDNA 1BRZA 1LQIA 2M8BB 1ZVGA 2K35A 5FPDA 1B3CA 2LJMA 1TI5A 1I2UA 2LR3A 3QMLA 4H5NA 1NGBA 5BPMA 5CY0A 1WWNA 3FZKA 3KOYA 4HHFA 2BRZA 2NY8X 1NGIA 1NRBA 1QQOA 4UADE 5AR0A 1NGJA 1WT7A 1KAYA 2N2QA 1T7BA 2QWMA 2D56A 5F0XA 1AYJA 3FE1A 5AQKA 4H5WA 1MR4A 5F2RA 5AQRA 5AQJA 3SF4D 2LN8A 5BN9A 3QFPA 5AQWA 1NGAA 1DQ7A 2KHOA 4CQKA 1LQQA 2VY6A 1BMRA 2E8AA 5BPLA 1KAXA 1C55A 2LT8A 1B7DA 3GDQA 3KOWA 1ZU3A 2E2FA 5BPNA 1VNBA 2KBKA 4H5VA 1MYNA 5AQMA 5AQVA 5AQGA 3R2VA 4FL9A 1BCGA 2KSKA 2QWNA 2QWRA 4HE7A 4IO8A 1BA1A 4V1DC 5AQXA 4AEIA 1T0ZA 1POIA 3FZHA 1OMYA 2ASCA 3HSCA 4H5RA 1GPSA 3LDLA 1T7AA 2LKBA 2YEOA 1L4VA 2ATBA 4KBOA 5EXWA 1ZUTA 2B3CA 2I61A 5EY4A 1JZAA 2KBJA 3C7NA 1XRSB 1NGGA 3FZMA 1DKGD 2MBKA 3CQXA 3GKUA 1VNAA 1T7EA 2NY9X 2E3FA 3KOXA 1AHOA 1ZYWA 1NRAA 5AQFA 5AQHA 1K8BA 3D2FA 3KOZA 1JZBA 3QFUA 3QI7A 2B68A 5AQIA 5FPNA 2LY6A 1ATRA 4AAZA 1OZZA 2QWQA 4FSVA 1WMTA 3IUCA 5AQNA 5AQUA 2BUPA 3LDOA 1HPMA 5AQLA 5AQSA 4UJ0A 5AQPA 3BK3C 1DJTA 2YIPA 1I6FA 2MZ0A 2N69A 3E7UX 2LJ7A 3KVGA 1JXCA 1NGFA 1KAZA 1ZFUA 1P00A 2KBHA 2QW9A 3GL1A 1BA0A 3ATVA 1BUPA 1SN4A 2KJAA 1NGCA 2E0HA 2YC1C 1SNBA 1HJOA 1NGHA 4GNIA 3D2EB 1HX1A 1SEGA 3M3ZA 3E7RL 3FZLA 5FPMA 2KPYA 3L4IA 2KGQA 1ZYVA 2SN3A 2V7ZA 1UGLA 5AQQA 1KV0A 3FZFA 1YUWA 3PSMA 1N4NA 2QWPA 5FPEA 1PE4A 2N2RA 1ZVEA 1I2VA 1NE5A 2E88A 1SN1A 5BN8A 1NGDA 2QXLA 1P0AA 2YILA 1QQNA 2N66A 3KHWA 4AB0A 1CHZA 4UAEF 1T1TA 2QWLA 3I33A 3L6QA 1GPTA 5EVZA 4UAFE 2A7TA 2GL1A 2QWOA 3KC6A 2YIOA 3A8YA 3AY9A 5AQYA 3LDQA 3C7NB 2E3GA 1CN2A 1ICAA 5EX5A 1PX9A 5AQTA 1C56A 1QQMA 4KYPA 5AQOA 1PTXA 5AQZA 3JXUA 1JKZA 5KK4A 1FH3A 1S3XA 3CW4A 2GMOA 2JDQD 1NH5A 2KYQA 3D2FB 3KP0A 2LY5A 2YBRC 3LDPA 2LI7A 3D2EA 1NPIA 5F1XA 1BK8A 1NGEA 2MN5A 1LQHA 1ATSA
chains in the Genus database with same CATH topology
3ATUA 3L56A 4H5TA 4HWIA 3LDNA 2K35A 5FPDA 3QMLA 4H5NA 1NGBA 5BPMA 3FZKA 1NGIA 1QQOA 4UADE 5AR0A 1NGJA 1KAYA 2QWMA 5F0XA 2D56A 3FE1A 5AQKA 4H5WA 5F2RA 5AQRA 5AQJA 3SF4D 2LN8A 5BN9A 3QFPA 5AQWA 1NGAA 2KHOA 2VY6A 2E8AA 5BPLA 1KAXA 3GDQA 2E2FA 5BPNA 4H5VA 5AQMA 5AQVA 5AQGA 3R2VA 4FL9A 2QWNA 4IO8A 2QWRA 1BA1A 5AQXA 1POIA 3FZHA 3HSCA 4H5RA 3LDLA 4KBOA 5EXWA 5EY4A 3C7NA 1NGGA 3FZMA 1DKGD 2MBKA 3CQXA 5AQFA 5AQHA 3D2FA 3QFUA 3QI7A 5AQIA 5FPNA 1ATRA 2QWQA 4FSVA 3IUCA 5AQNA 5AQUA 2BUPA 3LDOA 1HPMA 5AQLA 5AQSA 5AQPA 3BK3C 2YIPA 3KVGA 1NGFA 2QW9A 1KAZA 3GL1A 1BA0A 3ATVA 1BUPA 1NGCA 4GNIA 1NGHA 1HJOA 3D2EB 1HX1A 3M3ZA 5FPMA 3FZLA 3L4IA 2V7ZA 5AQQA 3FZFA 1YUWA 2QWPA 5FPEA 2E88A 5BN8A 1NGDA 2QXLA 2YILA 1QQNA 3KHWA 4UAEF 3L6QA 2QWLA 3I33A 5EVZA 4UAFE 2QWOA 3KC6A 2YIOA 3A8YA 3AY9A 5AQYA 3LDQA 3C7NB 5EX5A 5AQTA 1QQMA 5AQOA 5AQZA 3JXUA 1S3XA 3CW4A 2GMOA 2JDQD 3D2FB 3LDPA 3D2EA 5F1XA 1NGEA 2MN5A 1ATSA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3L56 A;  3CW4 A;  3KHW A;  2JDQ D;  2GMO A;  4UAE F;  4UAF E;  4UAD E;  3KC6 A;  2VY6 A;  3R2V A; 
#chains in the Genus database with same CATH topology
 3ATU A;  3L56 A;  1I6G A;  2G2K A;  4H5T A;  4HWI A;  3KP1 A;  3LDN A;  1BRZ A;  1LQI A;  2M8B B;  1ZVG A;  2K35 A;  5FPD A;  1B3C A;  2LJM A;  1TI5 A;  1I2U A;  2LR3 A;  3QML A;  4H5N A;  1NGB A;  5BPM A;  5CY0 A;  1WWN A;  3FZK A;  3KOY A;  4HHF A;  2BRZ A;  2NY8 X;  1NGI A;  1NRB A;  1QQO A;  4UAD E;  5AR0 A;  1NGJ A;  1WT7 A;  1KAY A;  2N2Q A;  1T7B A;  2QWM A;  2D56 A;  5F0X A;  1AYJ A;  3FE1 A;  5AQK A;  4H5W A;  1MR4 A;  5F2R A;  5AQR A;  5AQJ A;  3SF4 D;  2LN8 A;  5BN9 A;  3QFP A;  5AQW A;  1NGA A;  1DQ7 A;  2KHO A;  4CQK A;  1LQQ A;  2VY6 A;  1BMR A;  2E8A A;  5BPL A;  1KAX A;  1C55 A;  2LT8 A;  1B7D A;  3GDQ A;  3KOW A;  1ZU3 A;  2E2F A;  5BPN A;  1VNB A;  2KBK A;  4H5V A;  1MYN A;  5AQM A;  5AQV A;  5AQG A;  3R2V A;  4FL9 A;  1BCG A;  2KSK A;  2QWN A;  2QWR A;  4HE7 A;  4IO8 A;  1BA1 A;  4V1D C;  5AQX A;  4AEI A;  1T0Z A;  1POI A;  3FZH A;  1OMY A;  2ASC A;  3HSC A;  4H5R A;  1GPS A;  3LDL A;  1T7A A;  2LKB A;  2YEO A;  1L4V A;  2ATB A;  4KBO A;  5EXW A;  1ZUT A;  2B3C A;  2I61 A;  5EY4 A;  1JZA A;  2KBJ A;  3C7N A;  1XRS B;  1NGG A;  3FZM A;  1DKG D;  2MBK A;  3CQX A;  3GKU A;  1VNA A;  1T7E A;  2NY9 X;  2E3F A;  3KOX A;  1AHO A;  1ZYW A;  1NRA A;  5AQF A;  5AQH A;  1K8B A;  3D2F A;  3KOZ A;  1JZB A;  3QFU A;  3QI7 A;  2B68 A;  5AQI A;  5FPN A;  2LY6 A;  1ATR A;  4AAZ A;  1OZZ A;  2QWQ A;  4FSV A;  1WMT A;  3IUC A;  5AQN A;  5AQU A;  2BUP A;  3LDO A;  1HPM A;  5AQL A;  5AQS A;  4UJ0 A;  5AQP A;  3BK3 C;  1DJT A;  2YIP A;  1I6F A;  2MZ0 A;  2N69 A;  3E7U X;  2LJ7 A;  3KVG A;  1JXC A;  1NGF A;  1KAZ A;  1ZFU A;  1P00 A;  2KBH A;  2QW9 A;  3GL1 A;  1BA0 A;  3ATV A;  1BUP A;  1SN4 A;  2KJA A;  1NGC A;  2E0H A;  2YC1 C;  1SNB A;  1HJO A;  1NGH A;  4GNI A;  3D2E B;  1HX1 A;  1SEG A;  3M3Z A;  3E7R L;  3FZL A;  5FPM A;  2KPY A;  3L4I A;  2KGQ A;  1ZYV A;  2SN3 A;  2V7Z A;  1UGL A;  5AQQ A;  1KV0 A;  3FZF A;  1YUW A;  3PSM A;  1N4N A;  2QWP A;  5FPE A;  1PE4 A;  2N2R A;  1ZVE A;  1I2V A;  1NE5 A;  2E88 A;  1SN1 A;  5BN8 A;  1NGD A;  2QXL A;  1P0A A;  2YIL A;  1QQN A;  2N66 A;  3KHW A;  4AB0 A;  1CHZ A;  4UAE F;  1T1T A;  2QWL A;  3I33 A;  3L6Q A;  1GPT A;  5EVZ A;  4UAF E;  2A7T A;  2GL1 A;  2QWO A;  3KC6 A;  2YIO A;  3A8Y A;  3AY9 A;  5AQY A;  3LDQ A;  3C7N B;  2E3G A;  1CN2 A;  1ICA A;  5EX5 A;  1PX9 A;  5AQT A;  1C56 A;  1QQM A;  4KYP A;  5AQO A;  1PTX A;  5AQZ A;  3JXU A;  1JKZ A;  5KK4 A;  1FH3 A;  1S3X A;  3CW4 A;  2GMO A;  2JDQ D;  1NH5 A;  2KYQ A;  3D2F B;  3KP0 A;  2LY5 A;  2YBR C;  3LDP A;  2LI7 A;  3D2E A;  1NPI A;  5F1X A;  1BK8 A;  1NGE A;  2MN5 A;  1LQH A;  1ATS A; 
#chains in the Genus database with same CATH homology
 3ATU A;  3L56 A;  4H5T A;  4HWI A;  3LDN A;  2K35 A;  5FPD A;  3QML A;  4H5N A;  1NGB A;  5BPM A;  3FZK A;  1NGI A;  1QQO A;  4UAD E;  5AR0 A;  1NGJ A;  1KAY A;  2QWM A;  5F0X A;  2D56 A;  3FE1 A;  5AQK A;  4H5W A;  5F2R A;  5AQR A;  5AQJ A;  3SF4 D;  2LN8 A;  5BN9 A;  3QFP A;  5AQW A;  1NGA A;  2KHO A;  2VY6 A;  2E8A A;  5BPL A;  1KAX A;  3GDQ A;  2E2F A;  5BPN A;  4H5V A;  5AQM A;  5AQV A;  5AQG A;  3R2V A;  4FL9 A;  2QWN A;  4IO8 A;  2QWR A;  1BA1 A;  5AQX A;  1POI A;  3FZH A;  3HSC A;  4H5R A;  3LDL A;  4KBO A;  5EXW A;  5EY4 A;  3C7N A;  1NGG A;  3FZM A;  1DKG D;  2MBK A;  3CQX A;  5AQF A;  5AQH A;  3D2F A;  3QFU A;  3QI7 A;  5AQI A;  5FPN A;  1ATR A;  2QWQ A;  4FSV A;  3IUC A;  5AQN A;  5AQU A;  2BUP A;  3LDO A;  1HPM A;  5AQL A;  5AQS A;  5AQP A;  3BK3 C;  2YIP A;  3KVG A;  1NGF A;  2QW9 A;  1KAZ A;  3GL1 A;  1BA0 A;  3ATV A;  1BUP A;  1NGC A;  4GNI A;  1NGH A;  1HJO A;  3D2E B;  1HX1 A;  3M3Z A;  5FPM A;  3FZL A;  3L4I A;  2V7Z A;  5AQQ A;  3FZF A;  1YUW A;  2QWP A;  5FPE A;  2E88 A;  5BN8 A;  1NGD A;  2QXL A;  2YIL A;  1QQN A;  3KHW A;  4UAE F;  3L6Q A;  2QWL A;  3I33 A;  5EVZ A;  4UAF E;  2QWO A;  3KC6 A;  2YIO A;  3A8Y A;  3AY9 A;  5AQY A;  3LDQ A;  3C7N B;  5EX5 A;  5AQT A;  1QQM A;  5AQO A;  5AQZ A;  3JXU A;  1S3X A;  3CW4 A;  2GMO A;  2JDQ D;  3D2F B;  3LDP A;  3D2E A;  5F1X A;  1NGE A;  2MN5 A;  1ATS A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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