3KHWA

Crystal structure of the large c-terminal domain of polymerase basic protein 2 from influenza virus a/mexico/indre4487/2009(h1n1)
Total Genus 54
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
54
sequence length
201
structure length
201
Chain Sequence
GPESVLVNTYQWIIRNWEIVKIQWSQDPTMLYNKMEFEPFQSLVPKATRSRYSGFVRTLFQQMRDVLGTFDTVQIIKLLPFAAAPPEQSRMQFSSLTVNVRGSGLRILVRGNSPVFNYNKATKRLTVLGKDAGALTEDPDEGTSGVESAVLRGFLILGKEDKRYGPALSINELSNLAKGEKANVLIGQGDVVLVMKRKRDS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Biological and structural characterization of a host-adapting amino acid in influenza virus.
pubmed doi rcsb
molecule tags Viral protein
source organism Influenza a virus (a/mexico/indre4487/2009(h1n1))
molecule keywords Polymerase PB2
total genus 54
structure length 201
sequence length 201
chains with identical sequence B
ec nomenclature
pdb deposition date 2009-10-31
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.30.90 Alpha Beta 2-Layer Sandwich Defensin A-like Defensin A-like 3khwA02
3R2VA 3CW4A 4UADE 4UAFE 2VY6A 2GMOA 3KHWA 3L56A 4UAEF 2JDQD 3KC6A
chains in the Genus database with same CATH superfamily
1BCGA 1HJOA 1NGIA 2KPYA 2KHOA 2NY9X 3KOXA 5FPDA 5KK4A 2LI7A 1NGBA 2MBKA 1HX1A 3KOYA 1NRBA 2QWRA 5AQOA 5AQMA 3LDOA 1I6GA 3KC6A 1T0ZA 3D2EB 1ZUTA 1HPMA 1NGDA 1NGEA 5FPNA 1GPTA 2V7ZA 2E3GA 2KBJA 3ATVA 3C7NB 3M3ZA 5F0XA 1MR4A 2LN8A 5AQJA 3QI7A 1CHZA 3CW4A 1BA1A 3QFPA 2QWQA 5AQRA 5AQWA 1SN4A 2ASCA 1PE4A 2E2FA 5FPMA 4HWIA 1NGAA 4UAFE 4H5TA 4IO8A 5AQUA 2N66A 3A8YA 1I6FA 2E0HA 2E3FA 2G2KA 5AQVA 2KGQA 1AHOA 1ZU3A 2LY5A 2QW9A 1OMYA 2I61A 3L6QA 1JZAA 3FZLA 3LDLA 2GMOA 3SF4D 2E88A 3AY9A 5AQPA 2LR3A 3KVGA 1C55A 1T1TA 1JXCA 5BPLA 1KV0A 1ATSA 5AQTA 5EVZA 2KBKA 2KJAA 2LJMA 1ZYVA 2KBHA 2YIOA 2LT8A 4HE7A 3GL1A 1P0AA 1LQQA 4AB0A 4AEIA 4KYPA 1SNBA 1OZZA 1T7AA 1VNBA 1NRAA 1MYNA 2NY8X 2B3CA 3PSMA 1B3CA 1I2UA 1NE5A 1QQMA 1POIA 1LQHA 1QQOA 3FZMA 5CY0A 5F2RA 1NGHA 2YC1C 2M8BB 5FPEA 4H5WA 1AYJA 3JXUA 5AQKA 1NGCA 2K35A 3GDQA 3R2VA 2KYQA 1P00A 4H5RA 4H5VA 1ICAA 1C56A 1NGJA 3LDQA 1B7DA 2YBRC 3D2FA 3KP1A 1YUWA 4CQKA 1NGGA 2A7TA 2SN3A 3LDNA 1WMTA 4V1DC 2YEOA 2QWNA 5AQYA 5BPMA 1KAZA 3FE1A 3FZKA 1VNAA 1PX9A 3IUCA 1ZYWA 1K8BA 5AQXA 4AAZA 5AR0A 3E7UX 1CN2A 1T7EA 1NGFA 3KOWA 1DQ7A 4FSVA 1XRSB 2QXLA 5AQLA 2KSKA 2B68A 3L4IA 2N2QA 2QWPA 1WWNA 5BN8A 1KAXA 3FZHA 1S3XA 2QWOA 5BPNA 3KP0A 1KAYA 5F1XA 3E7RL 3KHWA 2D56A 1I2VA 2BUPA 1JZBA 1QQNA 2ATBA 2YIPA 3CQXA 2YILA 4UJ0A 1DKGD 2QWMA 2VY6A 5AQNA 3D2FB 2BRZA 5AQFA 1DJTA 2MN5A 5BN9A 1ATRA 1PTXA 1GPSA 1BMRA 3QMLA 5AQGA 1LQIA 1ZFUA 2E8AA 2LY6A 1N4NA 5EY4A 2LKBA 3D2EA 1ZVEA 3L56A 2JDQD 1FH3A 4FL9A 1BK8A 2N2RA 1TI5A 1T7BA 3C7NA 1BA0A 1SEGA 4GNIA 5AQIA 3KOZA 3ATUA 5AQSA 1ZVGA 2MZ0A 4H5NA 2N69A 3BK3C 3QFUA 5AQHA 1L4VA 3HSCA 2GL1A 3GKUA 5EX5A 2QWLA 1WT7A 1BUPA 3FZFA 4UADE 1NH5A 1UGLA 1JKZA 4KBOA 5AQQA 4HHFA 2LJ7A 1NPIA 3LDPA 4UAEF 1BRZA 1SN1A 3I33A 5AQZA 5EXWA
chains in the Genus database with same CATH topology
1HJOA 1NGIA 2KHOA 5FPDA 2MBKA 1NGBA 1HX1A 5AQMA 2QWRA 5AQOA 3LDOA 3KC6A 3D2EB 1HPMA 1NGDA 1NGEA 5FPNA 2V7ZA 3ATVA 3C7NB 3M3ZA 2LN8A 5AQJA 3QI7A 3CW4A 1BA1A 3QFPA 2QWQA 5AQRA 5AQWA 2E2FA 5FPMA 4HWIA 1NGAA 4UAFE 4H5TA 4IO8A 5AQUA 3A8YA 5AQVA 2QW9A 3L6QA 3FZLA 3LDLA 2GMOA 3SF4D 2E88A 3AY9A 5AQPA 3KVGA 5BPLA 1ATSA 5AQTA 5EVZA 2YIOA 5F0XA 3GL1A 1QQMA 1POIA 3FZMA 1QQOA 5F2RA 1NGHA 5FPEA 4H5WA 3JXUA 5AQKA 1NGCA 2K35A 3GDQA 3R2VA 4H5RA 4H5VA 1NGJA 3LDQA 3D2FA 1YUWA 1NGGA 3LDNA 5AQYA 5BPMA 2QWNA 1KAZA 3FE1A 3FZKA 3IUCA 5AQXA 5AR0A 1NGFA 4FSVA 2QXLA 5AQLA 3L4IA 2QWPA 5BN8A 1KAXA 3FZHA 1S3XA 2QWOA 5BPNA 5F1XA 1KAYA 3KHWA 2D56A 2BUPA 2YIPA 1QQNA 3CQXA 2YILA 1DKGD 2QWMA 2VY6A 5AQNA 3D2FB 5AQFA 2MN5A 5BN9A 1ATRA 3QMLA 5AQGA 2E8AA 5EY4A 3D2EA 3L56A 2JDQD 4FL9A 3C7NA 4GNIA 1BA0A 5AQIA 5AQSA 3ATUA 4H5NA 3BK3C 3QFUA 5AQHA 3HSCA 5EX5A 2QWLA 3FZFA 1BUPA 4UADE 4KBOA 5AQQA 3LDPA 4UAEF 3I33A 5AQZA 5EXWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3R2V A;  3CW4 A;  4UAD E;  4UAF E;  2VY6 A;  2GMO A;  3KHW A;  3L56 A;  4UAE F;  2JDQ D;  3KC6 A; 
#chains in the Genus database with same CATH topology
 1BCG A;  1HJO A;  1NGI A;  2KPY A;  2KHO A;  2NY9 X;  3KOX A;  5FPD A;  5KK4 A;  2LI7 A;  1NGB A;  2MBK A;  1HX1 A;  3KOY A;  1NRB A;  2QWR A;  5AQO A;  5AQM A;  3LDO A;  1I6G A;  3KC6 A;  1T0Z A;  3D2E B;  1ZUT A;  1HPM A;  1NGD A;  1NGE A;  5FPN A;  1GPT A;  2V7Z A;  2E3G A;  2KBJ A;  3ATV A;  3C7N B;  3M3Z A;  5F0X A;  1MR4 A;  2LN8 A;  5AQJ A;  3QI7 A;  1CHZ A;  3CW4 A;  1BA1 A;  3QFP A;  2QWQ A;  5AQR A;  5AQW A;  1SN4 A;  2ASC A;  1PE4 A;  2E2F A;  5FPM A;  4HWI A;  1NGA A;  4UAF E;  4H5T A;  4IO8 A;  5AQU A;  2N66 A;  3A8Y A;  1I6F A;  2E0H A;  2E3F A;  2G2K A;  5AQV A;  2KGQ A;  1AHO A;  1ZU3 A;  2LY5 A;  2QW9 A;  1OMY A;  2I61 A;  3L6Q A;  1JZA A;  3FZL A;  3LDL A;  2GMO A;  3SF4 D;  2E88 A;  3AY9 A;  5AQP A;  2LR3 A;  3KVG A;  1C55 A;  1T1T A;  1JXC A;  5BPL A;  1KV0 A;  1ATS A;  5AQT A;  5EVZ A;  2KBK A;  2KJA A;  2LJM A;  1ZYV A;  2KBH A;  2YIO A;  2LT8 A;  4HE7 A;  3GL1 A;  1P0A A;  1LQQ A;  4AB0 A;  4AEI A;  4KYP A;  1SNB A;  1OZZ A;  1T7A A;  1VNB A;  1NRA A;  1MYN A;  2NY8 X;  2B3C A;  3PSM A;  1B3C A;  1I2U A;  1NE5 A;  1QQM A;  1POI A;  1LQH A;  1QQO A;  3FZM A;  5CY0 A;  5F2R A;  1NGH A;  2YC1 C;  2M8B B;  5FPE A;  4H5W A;  1AYJ A;  3JXU A;  5AQK A;  1NGC A;  2K35 A;  3GDQ A;  3R2V A;  2KYQ A;  1P00 A;  4H5R A;  4H5V A;  1ICA A;  1C56 A;  1NGJ A;  3LDQ A;  1B7D A;  2YBR C;  3D2F A;  3KP1 A;  1YUW A;  4CQK A;  1NGG A;  2A7T A;  2SN3 A;  3LDN A;  1WMT A;  4V1D C;  2YEO A;  2QWN A;  5AQY A;  5BPM A;  1KAZ A;  3FE1 A;  3FZK A;  1VNA A;  1PX9 A;  3IUC A;  1ZYW A;  1K8B A;  5AQX A;  4AAZ A;  5AR0 A;  3E7U X;  1CN2 A;  1T7E A;  1NGF A;  3KOW A;  1DQ7 A;  4FSV A;  1XRS B;  2QXL A;  5AQL A;  2KSK A;  2B68 A;  3L4I A;  2N2Q A;  2QWP A;  1WWN A;  5BN8 A;  1KAX A;  3FZH A;  1S3X A;  2QWO A;  5BPN A;  3KP0 A;  1KAY A;  5F1X A;  3E7R L;  3KHW A;  2D56 A;  1I2V A;  2BUP A;  1JZB A;  1QQN A;  2ATB A;  2YIP A;  3CQX A;  2YIL A;  4UJ0 A;  1DKG D;  2QWM A;  2VY6 A;  5AQN A;  3D2F B;  2BRZ A;  5AQF A;  1DJT A;  2MN5 A;  5BN9 A;  1ATR A;  1PTX A;  1GPS A;  1BMR A;  3QML A;  5AQG A;  1LQI A;  1ZFU A;  2E8A A;  2LY6 A;  1N4N A;  5EY4 A;  2LKB A;  3D2E A;  1ZVE A;  3L56 A;  2JDQ D;  1FH3 A;  4FL9 A;  1BK8 A;  2N2R A;  1TI5 A;  1T7B A;  3C7N A;  1BA0 A;  1SEG A;  4GNI A;  5AQI A;  3KOZ A;  3ATU A;  5AQS A;  1ZVG A;  2MZ0 A;  4H5N A;  2N69 A;  3BK3 C;  3QFU A;  5AQH A;  1L4V A;  3HSC A;  2GL1 A;  3GKU A;  5EX5 A;  2QWL A;  1WT7 A;  1BUP A;  3FZF A;  4UAD E;  1NH5 A;  1UGL A;  1JKZ A;  4KBO A;  5AQQ A;  4HHF A;  2LJ7 A;  1NPI A;  3LDP A;  4UAE F;  1BRZ A;  1SN1 A;  3I33 A;  5AQZ A;  5EXW A; 
#chains in the Genus database with same CATH homology
 1HJO A;  1NGI A;  2KHO A;  5FPD A;  2MBK A;  1NGB A;  1HX1 A;  5AQM A;  2QWR A;  5AQO A;  3LDO A;  3KC6 A;  3D2E B;  1HPM A;  1NGD A;  1NGE A;  5FPN A;  2V7Z A;  3ATV A;  3C7N B;  3M3Z A;  2LN8 A;  5AQJ A;  3QI7 A;  3CW4 A;  1BA1 A;  3QFP A;  2QWQ A;  5AQR A;  5AQW A;  2E2F A;  5FPM A;  4HWI A;  1NGA A;  4UAF E;  4H5T A;  4IO8 A;  5AQU A;  3A8Y A;  5AQV A;  2QW9 A;  3L6Q A;  3FZL A;  3LDL A;  2GMO A;  3SF4 D;  2E88 A;  3AY9 A;  5AQP A;  3KVG A;  5BPL A;  1ATS A;  5AQT A;  5EVZ A;  2YIO A;  5F0X A;  3GL1 A;  1QQM A;  1POI A;  3FZM A;  1QQO A;  5F2R A;  1NGH A;  5FPE A;  4H5W A;  3JXU A;  5AQK A;  1NGC A;  2K35 A;  3GDQ A;  3R2V A;  4H5R A;  4H5V A;  1NGJ A;  3LDQ A;  3D2F A;  1YUW A;  1NGG A;  3LDN A;  5AQY A;  5BPM A;  2QWN A;  1KAZ A;  3FE1 A;  3FZK A;  3IUC A;  5AQX A;  5AR0 A;  1NGF A;  4FSV A;  2QXL A;  5AQL A;  3L4I A;  2QWP A;  5BN8 A;  1KAX A;  3FZH A;  1S3X A;  2QWO A;  5BPN A;  5F1X A;  1KAY A;  3KHW A;  2D56 A;  2BUP A;  2YIP A;  1QQN A;  3CQX A;  2YIL A;  1DKG D;  2QWM A;  2VY6 A;  5AQN A;  3D2F B;  5AQF A;  2MN5 A;  5BN9 A;  1ATR A;  3QML A;  5AQG A;  2E8A A;  5EY4 A;  3D2E A;  3L56 A;  2JDQ D;  4FL9 A;  3C7N A;  4GNI A;  1BA0 A;  5AQI A;  5AQS A;  3ATU A;  4H5N A;  3BK3 C;  3QFU A;  5AQH A;  3HSC A;  5EX5 A;  2QWL A;  3FZF A;  1BUP A;  4UAD E;  4KBO A;  5AQQ A;  3LDP A;  4UAE F;  3I33 A;  5AQZ A;  5EXW A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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