3KHWA

Crystal structure of the large c-terminal domain of polymerase basic protein 2 from influenza virus a/mexico/indre4487/2009(h1n1)
Total Genus 54
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
54
sequence length
201
structure length
201
Chain Sequence
GPESVLVNTYQWIIRNWEIVKIQWSQDPTMLYNKMEFEPFQSLVPKATRSRYSGFVRTLFQQMRDVLGTFDTVQIIKLLPFAAAPPEQSRMQFSSLTVNVRGSGLRILVRGNSPVFNYNKATKRLTVLGKDAGALTEDPDEGTSGVESAVLRGFLILGKEDKRYGPALSINELSNLAKGEKANVLIGQGDVVLVMKRKRDS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Biological and structural characterization of a host-adapting amino acid in influenza virus.
pubmed doi rcsb
molecule tags Viral protein
source organism Influenza a virus (a/mexico/indre4487/2009(h1n1))
molecule keywords Polymerase PB2
total genus 54
structure length 201
sequence length 201
chains with identical sequence B
ec nomenclature
pdb deposition date 2009-10-31
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.30.90 Alpha Beta 2-Layer Sandwich Defensin A-like Defensin A-like 3khwA02
3KHWA 3CW4A 3KC6A 4UADE 4UAEF 2GMOA 3R2VA 2VY6A 4UAFE 3L56A 2JDQD
chains in the Genus database with same CATH superfamily
1BK8A 2QWOA 1ZFUA 3KOZA 3HSCA 5AQIA 2QWLA 3FZMA 2E3FA 2LKBA 1C56A 1NGEA 5AQYA 3SF4D 1B3CA 1L4VA 3QFPA 1T0ZA 5AQGA 1QQOA 1JZBA 1SNBA 1DQ7A 2QWRA 2N66A 1PX9A 1T1TA 5AQXA 5AR0A 3QFUA 3R2VA 2ATBA 1GPTA 2G2KA 2E0HA 2QWNA 3GKUA 1AHOA 1VNAA 1WT7A 5AQVA 1SN1A 2QXLA 1BMRA 1JKZA 3KOWA 1S3XA 1OMYA 3D2FB 2KGQA 4UADE 5EX5A 2GMOA 1BUPA 4IO8A 2VY6A 1NPIA 2N2RA 5AQHA 3FZLA 1NGJA 1JXCA 1P00A 2LY6A 1NGAA 3GL1A 2KYQA 4HE7A 1HJOA 1MYNA 1JZAA 3KHWA 1NGCA 2QWMA 4GNIA 3E7RL 3JXUA 2B68A 1NRBA 2KBKA 1OZZA 5BPNA 3ATUA 1I6GA 3FZKA 3BK3C 1SEGA 3LDOA 4HHFA 5BPLA 5BN9A 3LDLA 2E8AA 4HWIA 1NE5A 2N2QA 4AAZA 3E7UX 2I61A 2SN3A 1DKGD 5AQLA 5KK4A 2LN8A 1KV0A 1NH5A 1NGDA 1VNBA 2GL1A 3I33A 2MBKA 2KBHA 1ZYWA 2BRZA 4H5VA 5AQKA 1I2UA 1NGBA 1NGGA 5FPMA 2YILA 2B3CA 3KVGA 2D56A 1I6FA 2E2FA 4H5TA 3FE1A 3L4IA 2E88A 4H5RA 1KAZA 1HPMA 1ZYVA 1MR4A 2JDQD 2NY8X 3CQXA 5F2RA 3KP1A 1QQMA 5F0XA 2N69A 1BRZA 1POIA 5AQRA 1ATSA 3GDQA 1QQNA 1ZVGA 3FZFA 1KAXA 3D2EA 1PE4A 1GPSA 1DJTA 5AQWA 1ICAA 2BUPA 1T7BA 1YUWA 1P0AA 2MN5A 1KAYA 4FSVA 2KHOA 1ZVEA 2A7TA 4KYPA 2KBJA 4H5NA 3FZHA 4AB0A 5FPDA 1K8BA 2LI7A 3LDPA 5CY0A 5FPEA 1CHZA 1NGFA 1ZUTA 2M8BB 4CQKA 4UAEF 3D2FA 5AQTA 1PTXA 5AQUA 3KOXA 2YC1C 1LQHA 2LJ7A 4H5WA 5AQNA 5FPNA 1SN4A 2ASCA 3L6QA 1T7EA 2YIPA 3ATVA 4AEIA 1C55A 1AYJA 1FH3A 2QWQA 2KSKA 3L56A 1BCGA 2MZ0A 3IUCA 1LQIA 3D2EB 1NRAA 1ZU3A 3C7NA 1NGHA 1LQQA 2NY9X 4V1DC 5BN8A 1BA1A 1I2VA 3M3ZA 1ATRA 2V7ZA 2QW9A 2YEOA 1NGIA 3PSMA 1HX1A 5AQZA 3KOYA 5AQSA 1UGLA 2LR3A 1WWNA 3LDNA 2LY5A 2E3GA 5AQOA 5EVZA 5EXWA 3CW4A 5BPMA 1CN2A 4UJ0A 3LDQA 3QMLA 1B7DA 1WMTA 1T7AA 2QWPA 4FL9A 5AQFA 2KJAA 1TI5A 5AQJA 5AQPA 5AQMA 5EY4A 3A8YA 2K35A 1BA0A 1N4NA 2LJMA 3AY9A 3KC6A 2KPYA 4KBOA 5AQQA 1XRSB 2LT8A 5F1XA 3QI7A 4UAFE 3KP0A 2YBRC 2YIOA 3C7NB
chains in the Genus database with same CATH topology
2QWOA 3HSCA 5AQIA 2QWLA 3FZMA 1NGEA 5AQYA 3SF4D 3QFPA 5AQGA 1QQOA 2QWRA 5AQXA 5AR0A 3QFUA 3R2VA 2QWNA 5AQVA 2QXLA 1S3XA 3D2FB 4UADE 5EX5A 2GMOA 1BUPA 4IO8A 2VY6A 5AQHA 3FZLA 1NGJA 3GL1A 1NGAA 1HJOA 3KHWA 1NGCA 2QWMA 4GNIA 3JXUA 5BPNA 3ATUA 3FZKA 3BK3C 3LDOA 5BPLA 5BN9A 3LDLA 2E8AA 4HWIA 1DKGD 5AQLA 2LN8A 1NGDA 3I33A 2MBKA 4H5VA 5AQKA 1NGBA 1NGGA 5FPMA 2YILA 3KVGA 2D56A 2E2FA 4H5TA 3FE1A 3L4IA 2E88A 4H5RA 1HPMA 1KAZA 2JDQD 3CQXA 5F2RA 1QQMA 5F0XA 1POIA 5AQRA 1ATSA 3GDQA 1QQNA 3FZFA 1KAXA 3D2EA 5AQWA 2BUPA 1YUWA 2MN5A 1KAYA 4FSVA 2KHOA 4H5NA 3FZHA 5FPDA 3LDPA 5FPEA 1NGFA 4UAEF 3D2FA 5AQTA 5AQUA 5AQNA 4H5WA 5FPNA 3L6QA 2YIPA 3ATVA 2QWQA 3L56A 3IUCA 3D2EB 3C7NA 1NGHA 5BN8A 1BA1A 3M3ZA 1ATRA 2V7ZA 2QW9A 1NGIA 5AQZA 1HX1A 5AQSA 3LDNA 5EXWA 5AQOA 5EVZA 3CW4A 5BPMA 3LDQA 3QMLA 2QWPA 5AQPA 4FL9A 5AQFA 5AQJA 5AQMA 5EY4A 3A8YA 2K35A 1BA0A 3AY9A 3KC6A 4KBOA 5AQQA 5F1XA 3QI7A 4UAFE 2YIOA 3C7NB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3KHW A;  3CW4 A;  3KC6 A;  4UAD E;  4UAE F;  2GMO A;  3R2V A;  2VY6 A;  4UAF E;  3L56 A;  2JDQ D; 
#chains in the Genus database with same CATH topology
 1BK8 A;  2QWO A;  1ZFU A;  3KOZ A;  3HSC A;  5AQI A;  2QWL A;  3FZM A;  2E3F A;  2LKB A;  1C56 A;  1NGE A;  5AQY A;  3SF4 D;  1B3C A;  1L4V A;  3QFP A;  1T0Z A;  5AQG A;  1QQO A;  1JZB A;  1SNB A;  1DQ7 A;  2QWR A;  2N66 A;  1PX9 A;  1T1T A;  5AQX A;  5AR0 A;  3QFU A;  3R2V A;  2ATB A;  1GPT A;  2G2K A;  2E0H A;  2QWN A;  3GKU A;  1AHO A;  1VNA A;  1WT7 A;  5AQV A;  1SN1 A;  2QXL A;  1BMR A;  1JKZ A;  3KOW A;  1S3X A;  1OMY A;  3D2F B;  2KGQ A;  4UAD E;  5EX5 A;  2GMO A;  1BUP A;  4IO8 A;  2VY6 A;  1NPI A;  2N2R A;  5AQH A;  3FZL A;  1NGJ A;  1JXC A;  1P00 A;  2LY6 A;  1NGA A;  3GL1 A;  2KYQ A;  4HE7 A;  1HJO A;  1MYN A;  1JZA A;  3KHW A;  1NGC A;  2QWM A;  4GNI A;  3E7R L;  3JXU A;  2B68 A;  1NRB A;  2KBK A;  1OZZ A;  5BPN A;  3ATU A;  1I6G A;  3FZK A;  3BK3 C;  1SEG A;  3LDO A;  4HHF A;  5BPL A;  5BN9 A;  3LDL A;  2E8A A;  4HWI A;  1NE5 A;  2N2Q A;  4AAZ A;  3E7U X;  2I61 A;  2SN3 A;  1DKG D;  5AQL A;  5KK4 A;  2LN8 A;  1KV0 A;  1NH5 A;  1NGD A;  1VNB A;  2GL1 A;  3I33 A;  2MBK A;  2KBH A;  1ZYW A;  2BRZ A;  4H5V A;  5AQK A;  1I2U A;  1NGB A;  1NGG A;  5FPM A;  2YIL A;  2B3C A;  3KVG A;  2D56 A;  1I6F A;  2E2F A;  4H5T A;  3FE1 A;  3L4I A;  2E88 A;  4H5R A;  1KAZ A;  1HPM A;  1ZYV A;  1MR4 A;  2JDQ D;  2NY8 X;  3CQX A;  5F2R A;  3KP1 A;  1QQM A;  5F0X A;  2N69 A;  1BRZ A;  1POI A;  5AQR A;  1ATS A;  3GDQ A;  1QQN A;  1ZVG A;  3FZF A;  1KAX A;  3D2E A;  1PE4 A;  1GPS A;  1DJT A;  5AQW A;  1ICA A;  2BUP A;  1T7B A;  1YUW A;  1P0A A;  2MN5 A;  1KAY A;  4FSV A;  2KHO A;  1ZVE A;  2A7T A;  4KYP A;  2KBJ A;  4H5N A;  3FZH A;  4AB0 A;  5FPD A;  1K8B A;  2LI7 A;  3LDP A;  5CY0 A;  5FPE A;  1CHZ A;  1NGF A;  1ZUT A;  2M8B B;  4CQK A;  4UAE F;  3D2F A;  5AQT A;  1PTX A;  5AQU A;  3KOX A;  2YC1 C;  1LQH A;  2LJ7 A;  4H5W A;  5AQN A;  5FPN A;  1SN4 A;  2ASC A;  3L6Q A;  1T7E A;  2YIP A;  3ATV A;  4AEI A;  1C55 A;  1AYJ A;  1FH3 A;  2QWQ A;  2KSK A;  3L56 A;  1BCG A;  2MZ0 A;  3IUC A;  1LQI A;  3D2E B;  1NRA A;  1ZU3 A;  3C7N A;  1NGH A;  1LQQ A;  2NY9 X;  4V1D C;  5BN8 A;  1BA1 A;  1I2V A;  3M3Z A;  1ATR A;  2V7Z A;  2QW9 A;  2YEO A;  1NGI A;  3PSM A;  1HX1 A;  5AQZ A;  3KOY A;  5AQS A;  1UGL A;  2LR3 A;  1WWN A;  3LDN A;  2LY5 A;  2E3G A;  5AQO A;  5EVZ A;  5EXW A;  3CW4 A;  5BPM A;  1CN2 A;  4UJ0 A;  3LDQ A;  3QML A;  1B7D A;  1WMT A;  1T7A A;  2QWP A;  4FL9 A;  5AQF A;  2KJA A;  1TI5 A;  5AQJ A;  5AQP A;  5AQM A;  5EY4 A;  3A8Y A;  2K35 A;  1BA0 A;  1N4N A;  2LJM A;  3AY9 A;  3KC6 A;  2KPY A;  4KBO A;  5AQQ A;  1XRS B;  2LT8 A;  5F1X A;  3QI7 A;  4UAF E;  3KP0 A;  2YBR C;  2YIO A;  3C7N B; 
#chains in the Genus database with same CATH homology
 2QWO A;  3HSC A;  5AQI A;  2QWL A;  3FZM A;  1NGE A;  5AQY A;  3SF4 D;  3QFP A;  5AQG A;  1QQO A;  2QWR A;  5AQX A;  5AR0 A;  3QFU A;  3R2V A;  2QWN A;  5AQV A;  2QXL A;  1S3X A;  3D2F B;  4UAD E;  5EX5 A;  2GMO A;  1BUP A;  4IO8 A;  2VY6 A;  5AQH A;  3FZL A;  1NGJ A;  3GL1 A;  1NGA A;  1HJO A;  3KHW A;  1NGC A;  2QWM A;  4GNI A;  3JXU A;  5BPN A;  3ATU A;  3FZK A;  3BK3 C;  3LDO A;  5BPL A;  5BN9 A;  3LDL A;  2E8A A;  4HWI A;  1DKG D;  5AQL A;  2LN8 A;  1NGD A;  3I33 A;  2MBK A;  4H5V A;  5AQK A;  1NGB A;  1NGG A;  5FPM A;  2YIL A;  3KVG A;  2D56 A;  2E2F A;  4H5T A;  3FE1 A;  3L4I A;  2E88 A;  4H5R A;  1HPM A;  1KAZ A;  2JDQ D;  3CQX A;  5F2R A;  1QQM A;  5F0X A;  1POI A;  5AQR A;  1ATS A;  3GDQ A;  1QQN A;  3FZF A;  1KAX A;  3D2E A;  5AQW A;  2BUP A;  1YUW A;  2MN5 A;  1KAY A;  4FSV A;  2KHO A;  4H5N A;  3FZH A;  5FPD A;  3LDP A;  5FPE A;  1NGF A;  4UAE F;  3D2F A;  5AQT A;  5AQU A;  5AQN A;  4H5W A;  5FPN A;  3L6Q A;  2YIP A;  3ATV A;  2QWQ A;  3L56 A;  3IUC A;  3D2E B;  3C7N A;  1NGH A;  5BN8 A;  1BA1 A;  3M3Z A;  1ATR A;  2V7Z A;  2QW9 A;  1NGI A;  5AQZ A;  1HX1 A;  5AQS A;  3LDN A;  5EXW A;  5AQO A;  5EVZ A;  3CW4 A;  5BPM A;  3LDQ A;  3QML A;  2QWP A;  5AQP A;  4FL9 A;  5AQF A;  5AQJ A;  5AQM A;  5EY4 A;  3A8Y A;  2K35 A;  1BA0 A;  3AY9 A;  3KC6 A;  4KBO A;  5AQQ A;  5F1X A;  3QI7 A;  4UAF E;  2YIO A;  3C7N B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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