3SF4D

Crystal structure of the complex between the conserved cell polarity proteins inscuteable and lgn
Total Genus 5
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
5
sequence length
45
structure length
45
Chain Sequence
QVDSVQRWMEDLKLMTECECMCVLQAKPISLEEDAQGDLILAGGP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis for interaction between the conserved cell polarity proteins Inscuteable and Leu-Gly-Asn repeat-enriched protein (LGN)
pubmed doi rcsb
molecule tags Signaling protein/protein binding
source organism Homo sapiens
molecule keywords G-protein-signaling modulator 2
total genus 5
structure length 45
sequence length 45
chains with identical sequence E, F
ec nomenclature
pdb deposition date 2011-06-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
D PF16748 INSC_LBD Inscuteable LGN-binding domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.30.160 Alpha Beta 2-Layer Sandwich Defensin A-like Defensin A-like 3sf4D00
3SF4D
chains in the Genus database with same CATH superfamily
2KJAA 3LDQA 1QQOA 2QWRA 1DQ7A 1NH5A 1HX1A 2QWQA 5EVZA 5AQGA 1ZVGA 1PX9A 2A7TA 1GPTA 5BN9A 1ZYWA 1HJOA 1T0ZA 3ATUA 2VY6A 2QWPA 1BMRA 1VNAA 1BA1A 2KHOA 4UADE 3PSMA 1UGLA 4FL9A 1KAXA 2BRZA 3CQXA 1LQQA 1I6GA 2MBKA 4UAFE 3FZHA 1ICAA 2NY8X 2E2FA 3KOYA 5AQHA 3FE1A 1B3CA 2LJMA 2ATBA 4UAEF 2N2QA 4CQKA 4UJ0A 1ZUTA 3C7NB 5EXWA 1BCGA 3CW4A 5BN8A 1L4VA 3KVGA 2GL1A 1JZAA 2KYQA 5AQKA 1HPMA 1BA0A 3D2EB 3KC6A 3KP1A 4AAZA 5AQWA 5AR0A 1I2VA 1BRZA 1MR4A 1ZVEA 2V7ZA 3FZKA 3C7NA 3L4IA 1QQMA 1NGGA 2QW9A 2YIPA 3L56A 1MYNA 4H5WA 4KBOA 5AQQA 4AB0A 5BPNA 2NY9X 2QWMA 1KV0A 3LDPA 2E3GA 1NGFA 3E7UX 3D2EA 5BPMA 1P00A 1NGEA 2LN8A 4V1DC 1OMYA 3IUCA 1ZFUA 2LY6A 1NPIA 3I33A 1NGCA 5CY0A 1NGIA 4KYPA 4AEIA 2LJ7A 2QWOA 1POIA 2MN5A 2YEOA 3QFUA 5EX5A 3AY9A 1CN2A 2KGQA 2LR3A 5FPNA 1ZYVA 2KPYA 2G2KA 4H5NA 1AHOA 1NGBA 1WT7A 3E7RL 5FPDA 1K8BA 1KAYA 2N66A 3KHWA 1NGAA 2K35A 3M3ZA 2YIOA 3LDNA 5AQZA 5AQLA 4HWIA 1PE4A 1VNBA 3D2FB 3HSCA 1T7AA 1OZZA 1ATSA 3KP0A 2ASCA 5AQJA 1NE5A 5F2RA 4HHFA 1B7DA 3FZFA 3KOWA 1XRSB 2N69A 4GNIA 2GMOA 2E3FA 3QMLA 2B68A 5AQSA 2KBHA 1NGDA 1N4NA 3QI7A 3D2FA 4H5VA 1PTXA 2LKBA 2SN3A 5AQRA 1AYJA 2N2RA 1P0AA 5AQOA 3R2VA 4FSVA 2QWLA 5KK4A 3L6QA 5AQMA 3GDQA 3JXUA 1GPSA 2QXLA 3A8YA 1NRAA 2YC1C 1SNBA 2KSKA 3LDOA 1NGHA 5BPLA 1NRBA 2KBJA 4H5RA 2LI7A 5AQNA 5EY4A 2QWNA 3SF4D 1T7EA 2YILA 3ATVA 5AQXA 1JXCA 4H5TA 5AQIA 5FPEA 3BK3C 1LQHA 5AQTA 5AQUA 1T7BA 5F1XA 3GKUA 2MZ0A 1QQNA 3GL1A 1SEGA 5AQPA 1WMTA 2LT8A 5AQFA 5AQVA 1T1TA 1I6FA 3LDLA 3KOXA 1ATRA 1BK8A 3QFPA 1C55A 1DKGD 1LQIA 2LY5A 2E0HA 5AQYA 1S3XA 1TI5A 4HE7A 2D56A 1ZU3A 2E88A 1NGJA 1FH3A 3FZMA 2E8AA 1JZBA 2BUPA 2I61A 1CHZA 2B3CA 3KOZA 1I2UA 3FZLA 5FPMA 1JKZA 2YBRC 2KBKA 1BUPA 1KAZA 1SN1A 1YUWA 1WWNA 4IO8A 1DJTA 1SN4A 5F0XA 2M8BB 2JDQD 1C56A
chains in the Genus database with same CATH topology
3LDQA 1QQOA 2QWRA 1HX1A 2QWQA 5AQGA 5BN9A 1HJOA 3ATUA 2VY6A 2QWPA 1BA1A 2KHOA 4UADE 4FL9A 1KAXA 3CQXA 2MBKA 4UAFE 3FZHA 2E2FA 5AQHA 3FE1A 4UAEF 5EXWA 3C7NB 3CW4A 5BN8A 3KVGA 5AQKA 1HPMA 1BA0A 3D2EB 3KC6A 5AQWA 5AR0A 2V7ZA 3FZKA 3L4IA 3C7NA 1QQMA 1NGGA 2QW9A 2YIPA 3L56A 4H5WA 4KBOA 5AQQA 5BPNA 2QWMA 3LDPA 1NGFA 3D2EA 5BPMA 1NGEA 2LN8A 3IUCA 3I33A 1NGCA 1NGIA 5EX5A 2QWOA 1POIA 2MN5A 3QFUA 3AY9A 5FPNA 4H5NA 1NGBA 5FPDA 1KAYA 3KHWA 1NGAA 2K35A 3M3ZA 2YIOA 3LDNA 5AQZA 5AQLA 4HWIA 3D2FB 3HSCA 5AQJA 1ATSA 5F2RA 3FZFA 4GNIA 2GMOA 3QMLA 5AQSA 1NGDA 3QI7A 3D2FA 4H5VA 5AQRA 5AQOA 3R2VA 4FSVA 2QWLA 3L6QA 5AQMA 3GDQA 3JXUA 2QXLA 3A8YA 3LDOA 1NGHA 5BPLA 4H5RA 5AQNA 5EY4A 2QWNA 3SF4D 2YILA 5FPEA 3ATVA 5AQXA 4H5TA 5AQIA 3BK3C 5AQTA 5AQUA 5F1XA 3GL1A 1QQNA 5AQPA 5AQVA 5AQFA 3LDLA 1ATRA 3QFPA 1DKGD 5AQYA 1S3XA 2D56A 2E88A 1NGJA 3FZMA 2E8AA 2BUPA 3FZLA 5FPMA 1BUPA 1KAZA 1YUWA 4IO8A 5F0XA 5EVZA 2JDQD
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3SF4 D; 
#chains in the Genus database with same CATH topology
 2KJA A;  3LDQ A;  1QQO A;  2QWR A;  1DQ7 A;  1NH5 A;  1HX1 A;  2QWQ A;  5EVZ A;  5AQG A;  1ZVG A;  1PX9 A;  2A7T A;  1GPT A;  5BN9 A;  1ZYW A;  1HJO A;  1T0Z A;  3ATU A;  2VY6 A;  2QWP A;  1BMR A;  1VNA A;  1BA1 A;  2KHO A;  4UAD E;  3PSM A;  1UGL A;  4FL9 A;  1KAX A;  2BRZ A;  3CQX A;  1LQQ A;  1I6G A;  2MBK A;  4UAF E;  3FZH A;  1ICA A;  2NY8 X;  2E2F A;  3KOY A;  5AQH A;  3FE1 A;  1B3C A;  2LJM A;  2ATB A;  4UAE F;  2N2Q A;  4CQK A;  4UJ0 A;  1ZUT A;  3C7N B;  5EXW A;  1BCG A;  3CW4 A;  5BN8 A;  1L4V A;  3KVG A;  2GL1 A;  1JZA A;  2KYQ A;  5AQK A;  1HPM A;  1BA0 A;  3D2E B;  3KC6 A;  3KP1 A;  4AAZ A;  5AQW A;  5AR0 A;  1I2V A;  1BRZ A;  1MR4 A;  1ZVE A;  2V7Z A;  3FZK A;  3C7N A;  3L4I A;  1QQM A;  1NGG A;  2QW9 A;  2YIP A;  3L56 A;  1MYN A;  4H5W A;  4KBO A;  5AQQ A;  4AB0 A;  5BPN A;  2NY9 X;  2QWM A;  1KV0 A;  3LDP A;  2E3G A;  1NGF A;  3E7U X;  3D2E A;  5BPM A;  1P00 A;  1NGE A;  2LN8 A;  4V1D C;  1OMY A;  3IUC A;  1ZFU A;  2LY6 A;  1NPI A;  3I33 A;  1NGC A;  5CY0 A;  1NGI A;  4KYP A;  4AEI A;  2LJ7 A;  2QWO A;  1POI A;  2MN5 A;  2YEO A;  3QFU A;  5EX5 A;  3AY9 A;  1CN2 A;  2KGQ A;  2LR3 A;  5FPN A;  1ZYV A;  2KPY A;  2G2K A;  4H5N A;  1AHO A;  1NGB A;  1WT7 A;  3E7R L;  5FPD A;  1K8B A;  1KAY A;  2N66 A;  3KHW A;  1NGA A;  2K35 A;  3M3Z A;  2YIO A;  3LDN A;  5AQZ A;  5AQL A;  4HWI A;  1PE4 A;  1VNB A;  3D2F B;  3HSC A;  1T7A A;  1OZZ A;  1ATS A;  3KP0 A;  2ASC A;  5AQJ A;  1NE5 A;  5F2R A;  4HHF A;  1B7D A;  3FZF A;  3KOW A;  1XRS B;  2N69 A;  4GNI A;  2GMO A;  2E3F A;  3QML A;  2B68 A;  5AQS A;  2KBH A;  1NGD A;  1N4N A;  3QI7 A;  3D2F A;  4H5V A;  1PTX A;  2LKB A;  2SN3 A;  5AQR A;  1AYJ A;  2N2R A;  1P0A A;  5AQO A;  3R2V A;  4FSV A;  2QWL A;  5KK4 A;  3L6Q A;  5AQM A;  3GDQ A;  3JXU A;  1GPS A;  2QXL A;  3A8Y A;  1NRA A;  2YC1 C;  1SNB A;  2KSK A;  3LDO A;  1NGH A;  5BPL A;  1NRB A;  2KBJ A;  4H5R A;  2LI7 A;  5AQN A;  5EY4 A;  2QWN A;  3SF4 D;  1T7E A;  2YIL A;  3ATV A;  5AQX A;  1JXC A;  4H5T A;  5AQI A;  5FPE A;  3BK3 C;  1LQH A;  5AQT A;  5AQU A;  1T7B A;  5F1X A;  3GKU A;  2MZ0 A;  1QQN A;  3GL1 A;  1SEG A;  5AQP A;  1WMT A;  2LT8 A;  5AQF A;  5AQV A;  1T1T A;  1I6F A;  3LDL A;  3KOX A;  1ATR A;  1BK8 A;  3QFP A;  1C55 A;  1DKG D;  1LQI A;  2LY5 A;  2E0H A;  5AQY A;  1S3X A;  1TI5 A;  4HE7 A;  2D56 A;  1ZU3 A;  2E88 A;  1NGJ A;  1FH3 A;  3FZM A;  2E8A A;  1JZB A;  2BUP A;  2I61 A;  1CHZ A;  2B3C A;  3KOZ A;  1I2U A;  3FZL A;  5FPM A;  1JKZ A;  2YBR C;  2KBK A;  1BUP A;  1KAZ A;  1SN1 A;  1YUW A;  1WWN A;  4IO8 A;  1DJT A;  1SN4 A;  5F0X A;  2M8B B;  2JDQ D;  1C56 A; 
#chains in the Genus database with same CATH homology
 3LDQ A;  1QQO A;  2QWR A;  1HX1 A;  2QWQ A;  5AQG A;  5BN9 A;  1HJO A;  3ATU A;  2VY6 A;  2QWP A;  1BA1 A;  2KHO A;  4UAD E;  4FL9 A;  1KAX A;  3CQX A;  2MBK A;  4UAF E;  3FZH A;  2E2F A;  5AQH A;  3FE1 A;  4UAE F;  5EXW A;  3C7N B;  3CW4 A;  5BN8 A;  3KVG A;  5AQK A;  1HPM A;  1BA0 A;  3D2E B;  3KC6 A;  5AQW A;  5AR0 A;  2V7Z A;  3FZK A;  3L4I A;  3C7N A;  1QQM A;  1NGG A;  2QW9 A;  2YIP A;  3L56 A;  4H5W A;  4KBO A;  5AQQ A;  5BPN A;  2QWM A;  3LDP A;  1NGF A;  3D2E A;  5BPM A;  1NGE A;  2LN8 A;  3IUC A;  3I33 A;  1NGC A;  1NGI A;  5EX5 A;  2QWO A;  1POI A;  2MN5 A;  3QFU A;  3AY9 A;  5FPN A;  4H5N A;  1NGB A;  5FPD A;  1KAY A;  3KHW A;  1NGA A;  2K35 A;  3M3Z A;  2YIO A;  3LDN A;  5AQZ A;  5AQL A;  4HWI A;  3D2F B;  3HSC A;  5AQJ A;  1ATS A;  5F2R A;  3FZF A;  4GNI A;  2GMO A;  3QML A;  5AQS A;  1NGD A;  3QI7 A;  3D2F A;  4H5V A;  5AQR A;  5AQO A;  3R2V A;  4FSV A;  2QWL A;  3L6Q A;  5AQM A;  3GDQ A;  3JXU A;  2QXL A;  3A8Y A;  3LDO A;  1NGH A;  5BPL A;  4H5R A;  5AQN A;  5EY4 A;  2QWN A;  3SF4 D;  2YIL A;  5FPE A;  3ATV A;  5AQX A;  4H5T A;  5AQI A;  3BK3 C;  5AQT A;  5AQU A;  5F1X A;  3GL1 A;  1QQN A;  5AQP A;  5AQV A;  5AQF A;  3LDL A;  1ATR A;  3QFP A;  1DKG D;  5AQY A;  1S3X A;  2D56 A;  2E88 A;  1NGJ A;  3FZM A;  2E8A A;  2BUP A;  3FZL A;  5FPM A;  1BUP A;  1KAZ A;  1YUW A;  4IO8 A;  5F0X A;  5EVZ A;  2JDQ D; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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