3BK3C

Crystal structure of the complex of bmp-2 and the first von willebrand domain type c of crossveinless-2
Total Genus 8
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
8
sequence length
67
structure length
67
Chain Sequence
WLITGTEASCENEGEVLHIPNITDNPCISCVCLNQKAECKQEKCAPLAEDCALVVKQTGACCEKCKG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure analysis reveals how the Chordin family member crossveinless 2 blocks BMP-2 receptor binding
pubmed doi rcsb
molecule tags Hormone/growth factor
source organism Homo sapiens
molecule keywords Bone morphogenetic protein 2
total genus 8
structure length 67
sequence length 67
chains with identical sequence D
ec nomenclature
pdb deposition date 2007-12-05
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.30.190 Alpha Beta 2-Layer Sandwich Defensin A-like Defensin A-like 3bk3C00
3BK3C 2MBKA
chains in the Genus database with same CATH superfamily
1PTXA 1BA1A 1JZBA 2QWPA 3KOYA 3R2VA 1GPTA 4UADE 2MN5A 5F0XA 1JKZA 1NGBA 2YILA 1ATSA 2V7ZA 4KYPA 3LDNA 5CY0A 2LKBA 5AQKA 1TI5A 5AQRA 3QMLA 5BN9A 2QWRA 3KVGA 2QWNA 1B7DA 3LDLA 4HE7A 2QWMA 1NGFA 2E3FA 5EXWA 3E7UX 1I6GA 4UAEF 3I33A 1POIA 3KP0A 1WMTA 1SNBA 2NY8X 3FE1A 3L4IA 2YIPA 2GL1A 2YEOA 3JXUA 1LQHA 1HJOA 2N66A 5AQGA 2D56A 1NGCA 2KBHA 5AQUA 2E3GA 2GMOA 1CHZA 2E2FA 1BRZA 1HPMA 1QQOA 2N2RA 2LJMA 1YUWA 1JXCA 5AQTA 4H5TA 3LDQA 4H5VA 2JDQD 3AY9A 1SEGA 5AQWA 2LY6A 1P0AA 1I2VA 2M8BB 2QWQA 5AQJA 5AQFA 2NY9X 5AQNA 2KJAA 5EVZA 3KOZA 3FZLA 1PX9A 3L6QA 1NGJA 1ZUTA 3FZHA 2E8AA 5AQOA 5FPEA 5AQVA 1BCGA 4FL9A 1KAZA 2MBKA 4UJ0A 1I6FA 1NRAA 1UGLA 4KBOA 1BA0A 1VNAA 2MZ0A 3GL1A 4UAFE 2ASCA 5BN8A 5BPLA 1NGAA 3KC6A 1BUPA 1LQQA 2QWOA 1QQMA 1FH3A 1ZYWA 3A8YA 3PSMA 1KV0A 3M3ZA 5FPMA 3QI7A 1T1TA 1T7BA 2YBRC 1SN4A 1ZU3A 2KBJA 2QWLA 3D2EA 1LQIA 1ZFUA 3KOXA 1WT7A 4IO8A 2LI7A 2K35A 2KBKA 1DJTA 1ATRA 1NGDA 1ZVGA 2A7TA 3D2FA 2B3CA 3IUCA 3L56A 1OMYA 5AQMA 1MR4A 1NGGA 1HX1A 1DQ7A 2B68A 1NRBA 3C7NA 5F2RA 5FPDA 1OZZA 3FZKA 3HSCA 1T7EA 1WWNA 1NPIA 1ZVEA 2E88A 1T7AA 2SN3A 2LY5A 4V1DC 5AQQA 3LDOA 4CQKA 5AQZA 2KSKA 1B3CA 2KYQA 2KHOA 2ATBA 3KP1A 1NE5A 1AYJA 5EX5A 2KGQA 5AQSA 1NGEA 1N4NA 1P00A 5AQIA 1QQNA 5F1XA 2LR3A 5BPMA 1NGIA 3FZFA 2LJ7A 3CW4A 3KHWA 4HWIA 1XRSB 4GNIA 2G2KA 3GKUA 1SN1A 3BK3C 2VY6A 2KPYA 3QFPA 5AR0A 3ATUA 3ATVA 3CQXA 3SF4D 4AB0A 1CN2A 2N2QA 4FSVA 2LT8A 5EY4A 2YC1C 4H5RA 1BK8A 5AQXA 2N69A 5AQPA 4H5WA 1C56A 1S3XA 1AHOA 1K8BA 1KAXA 4H5NA 3E7RL 1C55A 1BMRA 3KOWA 1DKGD 3D2EB 4HHFA 1MYNA 2E0HA 2YIOA 3FZMA 1NGHA 2I61A 5FPNA 5KK4A 1NH5A 1I2UA 2LN8A 1ZYVA 3GDQA 2BUPA 3D2FB 1KAYA 5AQLA 4AEIA 5BPNA 1L4VA 3C7NB 5AQYA 1T0ZA 1VNBA 2QW9A 2QXLA 1ICAA 1GPSA 2BRZA 1PE4A 3LDPA 3QFUA 5AQHA 4AAZA 1JZAA
chains in the Genus database with same CATH topology
2QWPA 1BA1A 3R2VA 2MN5A 5F0XA 1NGBA 2YILA 1ATSA 2V7ZA 3LDNA 5AQRA 5AQKA 3QMLA 5BN9A 2QWRA 3KVGA 2QWNA 3LDLA 2QWMA 1NGFA 5EXWA 4UAEF 3I33A 1POIA 3FE1A 3L4IA 2YIPA 3JXUA 1HJOA 5AQGA 2D56A 1NGCA 5AQUA 2GMOA 2E2FA 1HPMA 1QQOA 1YUWA 5AQTA 4H5TA 3LDQA 4H5VA 2JDQD 3AY9A 5AQWA 2QWQA 5AQFA 5AQJA 5EVZA 5AQNA 3FZLA 3L6QA 1NGJA 3FZHA 2E8AA 5AQOA 5FPEA 5AQVA 4FL9A 1KAZA 2MBKA 4KBOA 4UAFE 1BA0A 3GL1A 5BN8A 5BPLA 1NGAA 3KC6A 1BUPA 2QWOA 1QQMA 3A8YA 3M3ZA 3QI7A 3D2EA 4IO8A 2QWLA 5AQPA 4UADE 5FPMA 2K35A 5BPNA 1ATRA 1NGDA 3L56A 3D2FA 5AQMA 5FPNA 3IUCA 1NGGA 1HX1A 3C7NA 5F2RA 5FPDA 3FZKA 3HSCA 2E88A 5AQQA 3LDOA 5AQZA 2KHOA 5EX5A 5AQSA 1NGEA 5AQIA 1QQNA 5F1XA 5BPMA 1NGIA 3FZFA 3CW4A 3KHWA 4HWIA 4GNIA 3BK3C 2VY6A 3QFPA 5AR0A 3ATUA 3ATVA 3CQXA 3SF4D 4FSVA 5EY4A 4H5RA 5AQXA 4H5WA 1S3XA 1KAXA 4H5NA 1DKGD 3D2EB 2YIOA 3FZMA 1NGHA 2LN8A 3GDQA 2BUPA 3D2FB 1KAYA 5AQLA 3C7NB 5AQYA 2QW9A 2QXLA 3LDPA 3QFUA 5AQHA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3BK3 C;  2MBK A; 
#chains in the Genus database with same CATH topology
 1PTX A;  1BA1 A;  1JZB A;  2QWP A;  3KOY A;  3R2V A;  1GPT A;  4UAD E;  2MN5 A;  5F0X A;  1JKZ A;  1NGB A;  2YIL A;  1ATS A;  2V7Z A;  4KYP A;  3LDN A;  5CY0 A;  2LKB A;  5AQK A;  1TI5 A;  5AQR A;  3QML A;  5BN9 A;  2QWR A;  3KVG A;  2QWN A;  1B7D A;  3LDL A;  4HE7 A;  2QWM A;  1NGF A;  2E3F A;  5EXW A;  3E7U X;  1I6G A;  4UAE F;  3I33 A;  1POI A;  3KP0 A;  1WMT A;  1SNB A;  2NY8 X;  3FE1 A;  3L4I A;  2YIP A;  2GL1 A;  2YEO A;  3JXU A;  1LQH A;  1HJO A;  2N66 A;  5AQG A;  2D56 A;  1NGC A;  2KBH A;  5AQU A;  2E3G A;  2GMO A;  1CHZ A;  2E2F A;  1BRZ A;  1HPM A;  1QQO A;  2N2R A;  2LJM A;  1YUW A;  1JXC A;  5AQT A;  4H5T A;  3LDQ A;  4H5V A;  2JDQ D;  3AY9 A;  1SEG A;  5AQW A;  2LY6 A;  1P0A A;  1I2V A;  2M8B B;  2QWQ A;  5AQJ A;  5AQF A;  2NY9 X;  5AQN A;  2KJA A;  5EVZ A;  3KOZ A;  3FZL A;  1PX9 A;  3L6Q A;  1NGJ A;  1ZUT A;  3FZH A;  2E8A A;  5AQO A;  5FPE A;  5AQV A;  1BCG A;  4FL9 A;  1KAZ A;  2MBK A;  4UJ0 A;  1I6F A;  1NRA A;  1UGL A;  4KBO A;  1BA0 A;  1VNA A;  2MZ0 A;  3GL1 A;  4UAF E;  2ASC A;  5BN8 A;  5BPL A;  1NGA A;  3KC6 A;  1BUP A;  1LQQ A;  2QWO A;  1QQM A;  1FH3 A;  1ZYW A;  3A8Y A;  3PSM A;  1KV0 A;  3M3Z A;  5FPM A;  3QI7 A;  1T1T A;  1T7B A;  2YBR C;  1SN4 A;  1ZU3 A;  2KBJ A;  2QWL A;  3D2E A;  1LQI A;  1ZFU A;  3KOX A;  1WT7 A;  4IO8 A;  2LI7 A;  2K35 A;  2KBK A;  1DJT A;  1ATR A;  1NGD A;  1ZVG A;  2A7T A;  3D2F A;  2B3C A;  3IUC A;  3L56 A;  1OMY A;  5AQM A;  1MR4 A;  1NGG A;  1HX1 A;  1DQ7 A;  2B68 A;  1NRB A;  3C7N A;  5F2R A;  5FPD A;  1OZZ A;  3FZK A;  3HSC A;  1T7E A;  1WWN A;  1NPI A;  1ZVE A;  2E88 A;  1T7A A;  2SN3 A;  2LY5 A;  4V1D C;  5AQQ A;  3LDO A;  4CQK A;  5AQZ A;  2KSK A;  1B3C A;  2KYQ A;  2KHO A;  2ATB A;  3KP1 A;  1NE5 A;  1AYJ A;  5EX5 A;  2KGQ A;  5AQS A;  1NGE A;  1N4N A;  1P00 A;  5AQI A;  1QQN A;  5F1X A;  2LR3 A;  5BPM A;  1NGI A;  3FZF A;  2LJ7 A;  3CW4 A;  3KHW A;  4HWI A;  1XRS B;  4GNI A;  2G2K A;  3GKU A;  1SN1 A;  3BK3 C;  2VY6 A;  2KPY A;  3QFP A;  5AR0 A;  3ATU A;  3ATV A;  3CQX A;  3SF4 D;  4AB0 A;  1CN2 A;  2N2Q A;  4FSV A;  2LT8 A;  5EY4 A;  2YC1 C;  4H5R A;  1BK8 A;  5AQX A;  2N69 A;  5AQP A;  4H5W A;  1C56 A;  1S3X A;  1AHO A;  1K8B A;  1KAX A;  4H5N A;  3E7R L;  1C55 A;  1BMR A;  3KOW A;  1DKG D;  3D2E B;  4HHF A;  1MYN A;  2E0H A;  2YIO A;  3FZM A;  1NGH A;  2I61 A;  5FPN A;  5KK4 A;  1NH5 A;  1I2U A;  2LN8 A;  1ZYV A;  3GDQ A;  2BUP A;  3D2F B;  1KAY A;  5AQL A;  4AEI A;  5BPN A;  1L4V A;  3C7N B;  5AQY A;  1T0Z A;  1VNB A;  2QW9 A;  2QXL A;  1ICA A;  1GPS A;  2BRZ A;  1PE4 A;  3LDP A;  3QFU A;  5AQH A;  4AAZ A;  1JZA A; 
#chains in the Genus database with same CATH homology
 2QWP A;  1BA1 A;  3R2V A;  2MN5 A;  5F0X A;  1NGB A;  2YIL A;  1ATS A;  2V7Z A;  3LDN A;  5AQR A;  5AQK A;  3QML A;  5BN9 A;  2QWR A;  3KVG A;  2QWN A;  3LDL A;  2QWM A;  1NGF A;  5EXW A;  4UAE F;  3I33 A;  1POI A;  3FE1 A;  3L4I A;  2YIP A;  3JXU A;  1HJO A;  5AQG A;  2D56 A;  1NGC A;  5AQU A;  2GMO A;  2E2F A;  1HPM A;  1QQO A;  1YUW A;  5AQT A;  4H5T A;  3LDQ A;  4H5V A;  2JDQ D;  3AY9 A;  5AQW A;  2QWQ A;  5AQF A;  5AQJ A;  5EVZ A;  5AQN A;  3FZL A;  3L6Q A;  1NGJ A;  3FZH A;  2E8A A;  5AQO A;  5FPE A;  5AQV A;  4FL9 A;  1KAZ A;  2MBK A;  4KBO A;  4UAF E;  1BA0 A;  3GL1 A;  5BN8 A;  5BPL A;  1NGA A;  3KC6 A;  1BUP A;  2QWO A;  1QQM A;  3A8Y A;  3M3Z A;  3QI7 A;  3D2E A;  4IO8 A;  2QWL A;  5AQP A;  4UAD E;  5FPM A;  2K35 A;  5BPN A;  1ATR A;  1NGD A;  3L56 A;  3D2F A;  5AQM A;  5FPN A;  3IUC A;  1NGG A;  1HX1 A;  3C7N A;  5F2R A;  5FPD A;  3FZK A;  3HSC A;  2E88 A;  5AQQ A;  3LDO A;  5AQZ A;  2KHO A;  5EX5 A;  5AQS A;  1NGE A;  5AQI A;  1QQN A;  5F1X A;  5BPM A;  1NGI A;  3FZF A;  3CW4 A;  3KHW A;  4HWI A;  4GNI A;  3BK3 C;  2VY6 A;  3QFP A;  5AR0 A;  3ATU A;  3ATV A;  3CQX A;  3SF4 D;  4FSV A;  5EY4 A;  4H5R A;  5AQX A;  4H5W A;  1S3X A;  1KAX A;  4H5N A;  1DKG D;  3D2E B;  2YIO A;  3FZM A;  1NGH A;  2LN8 A;  3GDQ A;  2BUP A;  3D2F B;  1KAY A;  5AQL A;  3C7N B;  5AQY A;  2QW9 A;  2QXL A;  3LDP A;  3QFU A;  5AQH A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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