3CW4A

Large c-terminal domain of influenza a virus rna-dependent polymerase pb2
Total Genus 55
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
55
sequence length
208
structure length
208
Chain Sequence
MMWEINGPESVLVNTYQWIIRNWETVKIQWSQNPTMLYNKMEFEPFQSLVPKAIRGQYSGFVRTLFQQMRDVLGTFDTAQIIKLLPFAAAPPKQSRMQFSSFTVNVRGSGMRILVRGNSPVFNYNKATKRLTVLGKDAGTLTEDPDEGTAGVESAVLRGFLILGKEDKRYGPALSINELSNLAKGEKANVLIGQGDVVLVMKRKRDSS
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Structural basis of the influenza A virus RNA polymerase PB2 RNA-binding domain containing the pathogenicity-determinant lysine 627 residue
pubmed doi rcsb
molecule tags Transferase
source organism Influenza a virus
molecule keywords Polymerase basic protein 2
total genus 55
structure length 208
sequence length 208
ec nomenclature ec 2.7.-.-:
pdb deposition date 2008-04-21
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.30.90 Alpha Beta 2-Layer Sandwich Defensin A-like Defensin A-like 3cw4A02
2VY6A 4UADE 3L56A 4UAEF 3CW4A 3KHWA 3R2VA 4UAFE 2JDQD 2GMOA 3KC6A
chains in the Genus database with same CATH superfamily
1WWNA 3FE1A 2KBJA 2BUPA 2K35A 1PX9A 1MYNA 1T7BA 1NRBA 1NRAA 2YIPA 3BK3C 1QQMA 3FZMA 3L4IA 2E0HA 2QWNA 3D2EB 3HSCA 4HWIA 1C55A 1NGDA 5AQKA 5AQUA 2QWRA 1CHZA 1QQOA 3LDNA 2N2RA 1UGLA 1BRZA 1JXCA 2V7ZA 2YILA 3LDLA 1N4NA 4FSVA 2LN8A 1BMRA 5AQFA 4H5WA 4UJ0A 5F2RA 4CQKA 1ZU3A 3A8YA 5AQQA 2GL1A 1YUWA 2ATBA 2N2QA 2MZ0A 1PTXA 5AQTA 4AEIA 3IUCA 3SF4D 1GPTA 1OZZA 4UAEF 1HJOA 1NGJA 1KAXA 2QWQA 5FPDA 2KHOA 3KOZA 1NGGA 2MN5A 3D2FA 5BPNA 3CW4A 2D56A 4AB0A 5AQOA 2B3CA 1T7EA 2KPYA 3ATVA 1ZYWA 2QWPA 3C7NA 3QFUA 2I61A 1NGIA 2QW9A 5BPMA 1BUPA 3ATUA 3LDPA 1ATRA 1BK8A 2LJMA 2KBKA 5AR0A 1LQIA 5AQVA 1WT7A 3KOWA 4H5NA 1BA0A 4H5TA 3D2EA 5EVZA 2JDQD 1P00A 4H5RA 1HX1A 2YIOA 2QWMA 3KP1A 1FH3A 4H5VA 2N66A 1I2UA 2B68A 1ZFUA 1BA1A 4UAFE 1ZYVA 1ZVGA 5AQRA 5AQWA 1AYJA 2E3FA 1I2VA 1OMYA 1DQ7A 5AQNA 2GMOA 2N69A 3KOXA 3L6QA 5F0XA 3PSMA 5F1XA 1T7AA 1JZAA 1TI5A 1PE4A 1ICAA 3L56A 1DKGD 1LQHA 1NGAA 2QWLA 5AQLA 3M3ZA 3FZKA 1ATSA 1NGCA 3CQXA 3FZHA 2KJAA 3GDQA 3GL1A 5BPLA 2LY6A 2YEOA 5AQJA 5FPMA 2E3GA 2KYQA 5AQXA 3FZFA 4HE7A 5AQHA 2E8AA 1T1TA 5KK4A 2VY6A 2YBRC 2LY5A 2LKBA 2M8BB 2KGQA 2SN3A 1GPSA 1VNBA 1NGBA 1ZUTA 4HHFA 1MR4A 2A7TA 2NY9X 5AQSA 4KBOA 2ASCA 1HPMA 1B3CA 1I6GA 5EY4A 5FPEA 3E7UX 5AQMA 5AQZA 1QQNA 4IO8A 1JZBA 1NGHA 2LJ7A 3QI7A 3LDOA 5AQIA 2LR3A 1L4VA 5AQYA 1SEGA 1VNAA 1ZVEA 2E2FA 3KHWA 3R2VA 1I6FA 5EX5A 1KAYA 5AQPA 1B7DA 1KV0A 4FL9A 5BN9A 2E88A 1POIA 3E7RL 1NE5A 3GKUA 1XRSB 2NY8X 5FPNA 1CN2A 2KSKA 3LDQA 5CY0A 1C56A 2MBKA 3KVGA 1NPIA 1DJTA 2YC1C 3I33A 1BCGA 3KC6A 2LT8A 1KAZA 4KYPA 3JXUA 2LI7A 1AHOA 2QWOA 2KBHA 3KOYA 5AQGA 2G2KA 5EXWA 1LQQA 1NGEA 1K8BA 3D2FB 3QMLA 1T0ZA 4AAZA 4V1DC 1NGFA 1SN1A 3KP0A 1P0AA 2BRZA 1WMTA 3QFPA 4GNIA 4UADE 5BN8A 1NH5A 1SN4A 3AY9A 3C7NB 2QXLA 3FZLA 1JKZA 1S3XA 1SNBA
chains in the Genus database with same CATH topology
3FE1A 2BUPA 2K35A 3L4IA 3BK3C 2YIPA 3FZMA 1QQMA 2QWNA 3D2EB 3HSCA 4HWIA 1NGDA 5AQKA 5AQUA 2QWRA 1QQOA 3LDNA 2V7ZA 2YILA 3LDLA 4FSVA 2LN8A 5AQFA 4H5WA 5F2RA 3A8YA 5AQQA 1YUWA 5AQTA 3IUCA 3SF4D 1S3XA 4UAEF 1HJOA 1NGJA 1KAXA 2QWQA 5FPDA 2KHOA 1NGGA 2MN5A 3D2FA 5BPNA 3CW4A 2D56A 5AQOA 3ATVA 3C7NA 2QWPA 5BPMA 3QFUA 1NGIA 2QW9A 1BUPA 3ATUA 3LDPA 1ATRA 5AR0A 5AQVA 4H5NA 1BA0A 4H5TA 3D2EA 5EVZA 2JDQD 4H5RA 1HX1A 2YIOA 2QWMA 4H5VA 1BA1A 4UAFE 5AQRA 5AQWA 5AQNA 5F0XA 2GMOA 3L6QA 5F1XA 3L56A 1DKGD 1NGAA 2QWLA 5AQLA 3M3ZA 3FZKA 1ATSA 1NGCA 3CQXA 3FZHA 3GL1A 3GDQA 5BPLA 5AQJA 5FPMA 5AQXA 3FZFA 5AQHA 2E8AA 2VY6A 1NGBA 5AQSA 4KBOA 1HPMA 5EY4A 5FPEA 5AQMA 5AQZA 1QQNA 4IO8A 1NGHA 3QI7A 3LDOA 5AQIA 5AQYA 3KHWA 3R2VA 5EX5A 1KAYA 5AQPA 4FL9A 5BN9A 2E88A 1POIA 5FPNA 3LDQA 2MBKA 3KVGA 3I33A 3KC6A 1KAZA 3JXUA 2QWOA 5AQGA 5EXWA 1NGEA 3D2FB 3QMLA 1NGFA 4UADE 4GNIA 3QFPA 5BN8A 3C7NB 3AY9A 2QXLA 3FZLA 2E2FA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2VY6 A;  4UAD E;  3L56 A;  4UAE F;  3CW4 A;  3KHW A;  3R2V A;  4UAF E;  2JDQ D;  2GMO A;  3KC6 A; 
#chains in the Genus database with same CATH topology
 1WWN A;  3FE1 A;  2KBJ A;  2BUP A;  2K35 A;  1PX9 A;  1MYN A;  1T7B A;  1NRB A;  1NRA A;  2YIP A;  3BK3 C;  1QQM A;  3FZM A;  3L4I A;  2E0H A;  2QWN A;  3D2E B;  3HSC A;  4HWI A;  1C55 A;  1NGD A;  5AQK A;  5AQU A;  2QWR A;  1CHZ A;  1QQO A;  3LDN A;  2N2R A;  1UGL A;  1BRZ A;  1JXC A;  2V7Z A;  2YIL A;  3LDL A;  1N4N A;  4FSV A;  2LN8 A;  1BMR A;  5AQF A;  4H5W A;  4UJ0 A;  5F2R A;  4CQK A;  1ZU3 A;  3A8Y A;  5AQQ A;  2GL1 A;  1YUW A;  2ATB A;  2N2Q A;  2MZ0 A;  1PTX A;  5AQT A;  4AEI A;  3IUC A;  3SF4 D;  1GPT A;  1OZZ A;  4UAE F;  1HJO A;  1NGJ A;  1KAX A;  2QWQ A;  5FPD A;  2KHO A;  3KOZ A;  1NGG A;  2MN5 A;  3D2F A;  5BPN A;  3CW4 A;  2D56 A;  4AB0 A;  5AQO A;  2B3C A;  1T7E A;  2KPY A;  3ATV A;  1ZYW A;  2QWP A;  3C7N A;  3QFU A;  2I61 A;  1NGI A;  2QW9 A;  5BPM A;  1BUP A;  3ATU A;  3LDP A;  1ATR A;  1BK8 A;  2LJM A;  2KBK A;  5AR0 A;  1LQI A;  5AQV A;  1WT7 A;  3KOW A;  4H5N A;  1BA0 A;  4H5T A;  3D2E A;  5EVZ A;  2JDQ D;  1P00 A;  4H5R A;  1HX1 A;  2YIO A;  2QWM A;  3KP1 A;  1FH3 A;  4H5V A;  2N66 A;  1I2U A;  2B68 A;  1ZFU A;  1BA1 A;  4UAF E;  1ZYV A;  1ZVG A;  5AQR A;  5AQW A;  1AYJ A;  2E3F A;  1I2V A;  1OMY A;  1DQ7 A;  5AQN A;  2GMO A;  2N69 A;  3KOX A;  3L6Q A;  5F0X A;  3PSM A;  5F1X A;  1T7A A;  1JZA A;  1TI5 A;  1PE4 A;  1ICA A;  3L56 A;  1DKG D;  1LQH A;  1NGA A;  2QWL A;  5AQL A;  3M3Z A;  3FZK A;  1ATS A;  1NGC A;  3CQX A;  3FZH A;  2KJA A;  3GDQ A;  3GL1 A;  5BPL A;  2LY6 A;  2YEO A;  5AQJ A;  5FPM A;  2E3G A;  2KYQ A;  5AQX A;  3FZF A;  4HE7 A;  5AQH A;  2E8A A;  1T1T A;  5KK4 A;  2VY6 A;  2YBR C;  2LY5 A;  2LKB A;  2M8B B;  2KGQ A;  2SN3 A;  1GPS A;  1VNB A;  1NGB A;  1ZUT A;  4HHF A;  1MR4 A;  2A7T A;  2NY9 X;  5AQS A;  4KBO A;  2ASC A;  1HPM A;  1B3C A;  1I6G A;  5EY4 A;  5FPE A;  3E7U X;  5AQM A;  5AQZ A;  1QQN A;  4IO8 A;  1JZB A;  1NGH A;  2LJ7 A;  3QI7 A;  3LDO A;  5AQI A;  2LR3 A;  1L4V A;  5AQY A;  1SEG A;  1VNA A;  1ZVE A;  2E2F A;  3KHW A;  3R2V A;  1I6F A;  5EX5 A;  1KAY A;  5AQP A;  1B7D A;  1KV0 A;  4FL9 A;  5BN9 A;  2E88 A;  1POI A;  3E7R L;  1NE5 A;  3GKU A;  1XRS B;  2NY8 X;  5FPN A;  1CN2 A;  2KSK A;  3LDQ A;  5CY0 A;  1C56 A;  2MBK A;  3KVG A;  1NPI A;  1DJT A;  2YC1 C;  3I33 A;  1BCG A;  3KC6 A;  2LT8 A;  1KAZ A;  4KYP A;  3JXU A;  2LI7 A;  1AHO A;  2QWO A;  2KBH A;  3KOY A;  5AQG A;  2G2K A;  5EXW A;  1LQQ A;  1NGE A;  1K8B A;  3D2F B;  3QML A;  1T0Z A;  4AAZ A;  4V1D C;  1NGF A;  1SN1 A;  3KP0 A;  1P0A A;  2BRZ A;  1WMT A;  3QFP A;  4GNI A;  4UAD E;  5BN8 A;  1NH5 A;  1SN4 A;  3AY9 A;  3C7N B;  2QXL A;  3FZL A;  1JKZ A;  1S3X A;  1SNB A; 
#chains in the Genus database with same CATH homology
 3FE1 A;  2BUP A;  2K35 A;  3L4I A;  3BK3 C;  2YIP A;  3FZM A;  1QQM A;  2QWN A;  3D2E B;  3HSC A;  4HWI A;  1NGD A;  5AQK A;  5AQU A;  2QWR A;  1QQO A;  3LDN A;  2V7Z A;  2YIL A;  3LDL A;  4FSV A;  2LN8 A;  5AQF A;  4H5W A;  5F2R A;  3A8Y A;  5AQQ A;  1YUW A;  5AQT A;  3IUC A;  3SF4 D;  1S3X A;  4UAE F;  1HJO A;  1NGJ A;  1KAX A;  2QWQ A;  5FPD A;  2KHO A;  1NGG A;  2MN5 A;  3D2F A;  5BPN A;  3CW4 A;  2D56 A;  5AQO A;  3ATV A;  3C7N A;  2QWP A;  5BPM A;  3QFU A;  1NGI A;  2QW9 A;  1BUP A;  3ATU A;  3LDP A;  1ATR A;  5AR0 A;  5AQV A;  4H5N A;  1BA0 A;  4H5T A;  3D2E A;  5EVZ A;  2JDQ D;  4H5R A;  1HX1 A;  2YIO A;  2QWM A;  4H5V A;  1BA1 A;  4UAF E;  5AQR A;  5AQW A;  5AQN A;  5F0X A;  2GMO A;  3L6Q A;  5F1X A;  3L56 A;  1DKG D;  1NGA A;  2QWL A;  5AQL A;  3M3Z A;  3FZK A;  1ATS A;  1NGC A;  3CQX A;  3FZH A;  3GL1 A;  3GDQ A;  5BPL A;  5AQJ A;  5FPM A;  5AQX A;  3FZF A;  5AQH A;  2E8A A;  2VY6 A;  1NGB A;  5AQS A;  4KBO A;  1HPM A;  5EY4 A;  5FPE A;  5AQM A;  5AQZ A;  1QQN A;  4IO8 A;  1NGH A;  3QI7 A;  3LDO A;  5AQI A;  5AQY A;  3KHW A;  3R2V A;  5EX5 A;  1KAY A;  5AQP A;  4FL9 A;  5BN9 A;  2E88 A;  1POI A;  5FPN A;  3LDQ A;  2MBK A;  3KVG A;  3I33 A;  3KC6 A;  1KAZ A;  3JXU A;  2QWO A;  5AQG A;  5EXW A;  1NGE A;  3D2F B;  3QML A;  1NGF A;  4UAD E;  4GNI A;  3QFP A;  5BN8 A;  3C7N B;  3AY9 A;  2QXL A;  3FZL A;  2E2F A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...