3SF4D

Crystal structure of the complex between the conserved cell polarity proteins inscuteable and lgn
Total Genus 5
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
5
sequence length
45
structure length
45
Chain Sequence
QVDSVQRWMEDLKLMTECECMCVLQAKPISLEEDAQGDLILAGGP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis for interaction between the conserved cell polarity proteins Inscuteable and Leu-Gly-Asn repeat-enriched protein (LGN)
pubmed doi rcsb
molecule tags Signaling protein/protein binding
source organism Homo sapiens
molecule keywords G-protein-signaling modulator 2
total genus 5
structure length 45
sequence length 45
chains with identical sequence E, F
ec nomenclature
pdb deposition date 2011-06-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
D PF16748 INSC_LBD Inscuteable LGN-binding domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.30.160 Alpha Beta 2-Layer Sandwich Defensin A-like Defensin A-like 3sf4D00
3SF4D
chains in the Genus database with same CATH superfamily
1NGAA 3M3ZA 2E0HA 3GDQA 2YEOA 1T7AA 1ZUTA 2B68A 2LJMA 1VNBA 2E3FA 1B7DA 2E8AA 1NRBA 2LKBA 1CN2A 1BUPA 5AQNA 2KSKA 1C56A 1NGDA 5AQTA 2E2FA 4H5NA 1QQMA 3L6QA 3FZMA 2YILA 2LY6A 2LT8A 2YC1C 3QI7A 1JKZA 5AQPA 3L4IA 2JDQD 2LY5A 1T1TA 2KBKA 1QQOA 3KP0A 1DQ7A 2LR3A 5AQMA 2GL1A 5AQVA 4AB0A 1T0ZA 2D56A 3D2FA 1WMTA 3HSCA 3LDNA 3LDPA 5AQZA 1DJTA 3CW4A 1T7BA 3KVGA 1WT7A 1BMRA 5F0XA 2QWNA 3KOWA 2N69A 2KYQA 3BK3C 1KAZA 1XRSB 1ZU3A 5AQRA 1OMYA 5KK4A 4KYPA 5AQJA 3CQXA 1JXCA 4V1DC 1VNAA 2NY8X 2QWLA 4AEIA 1SN4A 2NY9X 1GPSA 5AQFA 1BRZA 1ZVGA 1KAXA 3KOXA 5BPMA 1GPTA 3KOYA 2V7ZA 1B3CA 3FZLA 5AQHA 2E3GA 3IUCA 2M8BB 3AY9A 2N66A 4HWIA 1KAYA 3E7UX 1HX1A 2B3CA 2K35A 1KV0A 1SNBA 5AQYA 5BN8A 1NGIA 1JZAA 1I2UA 5FPDA 1WWNA 5EVZA 1DKGD 4UAFE 1T7EA 3FZFA 1ICAA 5FPEA 5EX5A 2QW9A 1HJOA 1NGFA 1SN1A 1TI5A 2BRZA 4HHFA 5AQIA 1BK8A 5AQUA 2E88A 4UADE 5F2RA 1POIA 2KGQA 3R2VA 2KPYA 3QFUA 3FZHA 3L56A 1YUWA 3QMLA 1I6FA 3GKUA 2KHOA 1BA0A 2G2KA 2QWQA 2QWRA 3C7NB 5AQSA 5BPNA 1NGCA 1QQNA 1ZYVA 5AQKA 1LQQA 2LJ7A 4GNIA 2ATBA 4UAEF 4UJ0A 4HE7A 3GL1A 2KBHA 4CQKA 1ATRA 3D2FB 1K8BA 3D2EB 1FH3A 2LI7A 4FL9A 2YBRC 3FE1A 1NH5A 5BPLA 2BUPA 2VY6A 5FPNA 2GMOA 2MN5A 3JXUA 1CHZA 4IO8A 2QWMA 5BN9A 5CY0A 1L4VA 1NGBA 1NGJA 1P0AA 3ATVA 4FSVA 1BCGA 1P00A 4H5RA 1JZBA 3LDQA 4H5WA 4AAZA 3LDOA 1NGGA 1UGLA 5EXWA 3KHWA 2A7TA 4KBOA 1NE5A 5AQGA 4H5TA 2QWPA 5AQQA 1NGEA 1HPMA 1LQHA 1ZVEA 2YIOA 1I6GA 1NRAA 2MBKA 2MZ0A 3LDLA 3E7RL 3C7NA 3KOZA 1S3XA 3KP1A 5FPMA 2I61A 1ATSA 2ASCA 5AQXA 5AQLA 1PE4A 3KC6A 1C55A 2KJAA 1BA1A 1AYJA 1ZFUA 2QXLA 5AR0A 1N4NA 5AQWA 5F1XA 1MR4A 1PX9A 3PSMA 3QFPA 2N2QA 3I33A 5AQOA 3D2EA 5EY4A 1MYNA 2N2RA 2QWOA 1PTXA 1SEGA 2LN8A 1ZYWA 2YIPA 3SF4D 1I2VA 1AHOA 1OZZA 3ATUA 1NPIA 4H5VA 1NGHA 2KBJA 2SN3A 1LQIA 3A8YA 3FZKA
chains in the Genus database with same CATH topology
1NGAA 3M3ZA 3GDQA 2E8AA 1BUPA 5AQNA 1NGDA 5AQTA 2E2FA 4H5NA 1QQMA 3L6QA 3FZMA 2YILA 3QI7A 5AQPA 3L4IA 2JDQD 1QQOA 5AQMA 5AQVA 2D56A 3D2FA 3LDNA 3HSCA 3LDPA 5AQZA 3CW4A 3KVGA 5F0XA 2QWNA 3BK3C 1KAZA 5AQRA 5AQJA 3CQXA 2QWLA 5AQFA 1KAXA 5BPMA 2V7ZA 3FZLA 5AQHA 3IUCA 3AY9A 4HWIA 1KAYA 1HX1A 2K35A 5AQYA 5BN8A 1NGIA 5FPDA 5EVZA 1DKGD 4UAFE 3FZFA 5FPEA 5EX5A 2QW9A 1HJOA 1NGFA 5AQIA 5AQUA 2E88A 4UADE 5F2RA 1POIA 3R2VA 3QFUA 3FZHA 3L56A 1YUWA 3QMLA 2KHOA 1BA0A 2QWQA 2QWRA 3C7NB 5AQSA 5BPNA 1NGCA 1QQNA 5AQKA 4UAEF 4GNIA 3GL1A 1ATRA 3D2FB 3D2EB 4FL9A 3FE1A 5BPLA 2BUPA 2VY6A 5FPNA 2GMOA 2MN5A 3JXUA 4IO8A 2QWMA 5BN9A 1NGBA 1NGJA 3ATVA 4FSVA 4H5RA 3LDQA 4H5WA 3LDOA 1NGGA 5EXWA 3KHWA 4KBOA 5AQGA 4H5TA 2QWPA 5AQQA 1NGEA 1HPMA 2YIOA 2MBKA 3LDLA 3C7NA 1S3XA 1ATSA 5AQXA 5AQLA 3KC6A 1BA1A 2QXLA 5AR0A 5F1XA 5AQWA 3QFPA 5AQOA 3I33A 3D2EA 5EY4A 2QWOA 2LN8A 2YIPA 3SF4D 3ATUA 4H5VA 1NGHA 5FPMA 3A8YA 3FZKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3SF4 D; 
#chains in the Genus database with same CATH topology
 1NGA A;  3M3Z A;  2E0H A;  3GDQ A;  2YEO A;  1T7A A;  1ZUT A;  2B68 A;  2LJM A;  1VNB A;  2E3F A;  1B7D A;  2E8A A;  1NRB A;  2LKB A;  1CN2 A;  1BUP A;  5AQN A;  2KSK A;  1C56 A;  1NGD A;  5AQT A;  2E2F A;  4H5N A;  1QQM A;  3L6Q A;  3FZM A;  2YIL A;  2LY6 A;  2LT8 A;  2YC1 C;  3QI7 A;  1JKZ A;  5AQP A;  3L4I A;  2JDQ D;  2LY5 A;  1T1T A;  2KBK A;  1QQO A;  3KP0 A;  1DQ7 A;  2LR3 A;  5AQM A;  2GL1 A;  5AQV A;  4AB0 A;  1T0Z A;  2D56 A;  3D2F A;  1WMT A;  3HSC A;  3LDN A;  3LDP A;  5AQZ A;  1DJT A;  3CW4 A;  1T7B A;  3KVG A;  1WT7 A;  1BMR A;  5F0X A;  2QWN A;  3KOW A;  2N69 A;  2KYQ A;  3BK3 C;  1KAZ A;  1XRS B;  1ZU3 A;  5AQR A;  1OMY A;  5KK4 A;  4KYP A;  5AQJ A;  3CQX A;  1JXC A;  4V1D C;  1VNA A;  2NY8 X;  2QWL A;  4AEI A;  1SN4 A;  2NY9 X;  1GPS A;  5AQF A;  1BRZ A;  1ZVG A;  1KAX A;  3KOX A;  5BPM A;  1GPT A;  3KOY A;  2V7Z A;  1B3C A;  3FZL A;  5AQH A;  2E3G A;  3IUC A;  2M8B B;  3AY9 A;  2N66 A;  4HWI A;  1KAY A;  3E7U X;  1HX1 A;  2B3C A;  2K35 A;  1KV0 A;  1SNB A;  5AQY A;  5BN8 A;  1NGI A;  1JZA A;  1I2U A;  5FPD A;  1WWN A;  5EVZ A;  1DKG D;  4UAF E;  1T7E A;  3FZF A;  1ICA A;  5FPE A;  5EX5 A;  2QW9 A;  1HJO A;  1NGF A;  1SN1 A;  1TI5 A;  2BRZ A;  4HHF A;  5AQI A;  1BK8 A;  5AQU A;  2E88 A;  4UAD E;  5F2R A;  1POI A;  2KGQ A;  3R2V A;  2KPY A;  3QFU A;  3FZH A;  3L56 A;  1YUW A;  3QML A;  1I6F A;  3GKU A;  2KHO A;  1BA0 A;  2G2K A;  2QWQ A;  2QWR A;  3C7N B;  5AQS A;  5BPN A;  1NGC A;  1QQN A;  1ZYV A;  5AQK A;  1LQQ A;  2LJ7 A;  4GNI A;  2ATB A;  4UAE F;  4UJ0 A;  4HE7 A;  3GL1 A;  2KBH A;  4CQK A;  1ATR A;  3D2F B;  1K8B A;  3D2E B;  1FH3 A;  2LI7 A;  4FL9 A;  2YBR C;  3FE1 A;  1NH5 A;  5BPL A;  2BUP A;  2VY6 A;  5FPN A;  2GMO A;  2MN5 A;  3JXU A;  1CHZ A;  4IO8 A;  2QWM A;  5BN9 A;  5CY0 A;  1L4V A;  1NGB A;  1NGJ A;  1P0A A;  3ATV A;  4FSV A;  1BCG A;  1P00 A;  4H5R A;  1JZB A;  3LDQ A;  4H5W A;  4AAZ A;  3LDO A;  1NGG A;  1UGL A;  5EXW A;  3KHW A;  2A7T A;  4KBO A;  1NE5 A;  5AQG A;  4H5T A;  2QWP A;  5AQQ A;  1NGE A;  1HPM A;  1LQH A;  1ZVE A;  2YIO A;  1I6G A;  1NRA A;  2MBK A;  2MZ0 A;  3LDL A;  3E7R L;  3C7N A;  3KOZ A;  1S3X A;  3KP1 A;  5FPM A;  2I61 A;  1ATS A;  2ASC A;  5AQX A;  5AQL A;  1PE4 A;  3KC6 A;  1C55 A;  2KJA A;  1BA1 A;  1AYJ A;  1ZFU A;  2QXL A;  5AR0 A;  1N4N A;  5AQW A;  5F1X A;  1MR4 A;  1PX9 A;  3PSM A;  3QFP A;  2N2Q A;  3I33 A;  5AQO A;  3D2E A;  5EY4 A;  1MYN A;  2N2R A;  2QWO A;  1PTX A;  1SEG A;  2LN8 A;  1ZYW A;  2YIP A;  3SF4 D;  1I2V A;  1AHO A;  1OZZ A;  3ATU A;  1NPI A;  4H5V A;  1NGH A;  2KBJ A;  2SN3 A;  1LQI A;  3A8Y A;  3FZK A; 
#chains in the Genus database with same CATH homology
 1NGA A;  3M3Z A;  3GDQ A;  2E8A A;  1BUP A;  5AQN A;  1NGD A;  5AQT A;  2E2F A;  4H5N A;  1QQM A;  3L6Q A;  3FZM A;  2YIL A;  3QI7 A;  5AQP A;  3L4I A;  2JDQ D;  1QQO A;  5AQM A;  5AQV A;  2D56 A;  3D2F A;  3LDN A;  3HSC A;  3LDP A;  5AQZ A;  3CW4 A;  3KVG A;  5F0X A;  2QWN A;  3BK3 C;  1KAZ A;  5AQR A;  5AQJ A;  3CQX A;  2QWL A;  5AQF A;  1KAX A;  5BPM A;  2V7Z A;  3FZL A;  5AQH A;  3IUC A;  3AY9 A;  4HWI A;  1KAY A;  1HX1 A;  2K35 A;  5AQY A;  5BN8 A;  1NGI A;  5FPD A;  5EVZ A;  1DKG D;  4UAF E;  3FZF A;  5FPE A;  5EX5 A;  2QW9 A;  1HJO A;  1NGF A;  5AQI A;  5AQU A;  2E88 A;  4UAD E;  5F2R A;  1POI A;  3R2V A;  3QFU A;  3FZH A;  3L56 A;  1YUW A;  3QML A;  2KHO A;  1BA0 A;  2QWQ A;  2QWR A;  3C7N B;  5AQS A;  5BPN A;  1NGC A;  1QQN A;  5AQK A;  4UAE F;  4GNI A;  3GL1 A;  1ATR A;  3D2F B;  3D2E B;  4FL9 A;  3FE1 A;  5BPL A;  2BUP A;  2VY6 A;  5FPN A;  2GMO A;  2MN5 A;  3JXU A;  4IO8 A;  2QWM A;  5BN9 A;  1NGB A;  1NGJ A;  3ATV A;  4FSV A;  4H5R A;  3LDQ A;  4H5W A;  3LDO A;  1NGG A;  5EXW A;  3KHW A;  4KBO A;  5AQG A;  4H5T A;  2QWP A;  5AQQ A;  1NGE A;  1HPM A;  2YIO A;  2MBK A;  3LDL A;  3C7N A;  1S3X A;  1ATS A;  5AQX A;  5AQL A;  3KC6 A;  1BA1 A;  2QXL A;  5AR0 A;  5F1X A;  5AQW A;  3QFP A;  5AQO A;  3I33 A;  3D2E A;  5EY4 A;  2QWO A;  2LN8 A;  2YIP A;  3SF4 D;  3ATU A;  4H5V A;  1NGH A;  5FPM A;  3A8Y A;  3FZK A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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