4HHFA

Crystal structure of chemically synthesized scorpion alpha-toxin od1
Total Genus 17
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
17
sequence length
65
structure length
65
Chain Sequence
GVRDAYIADDKNCVYTCASNGYCNTECTKNGAESGYCQWIGRYGNACWCIKLPDEVPIRIPGKCR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Chemical engineering and structural and pharmacological characterization of the alpha-scorpion toxin OD1.
pubmed doi rcsb
molecule tags Toxin
molecule keywords Alpha-toxin OD1
total genus 17
structure length 65
sequence length 65
ec nomenclature
pdb deposition date 2012-10-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00537 Toxin_3 Scorpion toxin-like domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.30.10 Alpha Beta 2-Layer Sandwich Defensin A-like Knottin, scorpion toxin-like 4hhfA00
3E7RL 1LQQA 1ZVEA 1DJTA 2N66A 1ZUTA 1OZZA 1BK8A 1ZU3A 4KYPA 1NRBA 2KYQA 2B3CA 2E3FA 1T0ZA 2LI7A 2YC1C 1PX9A 2YEOA 1MR4A 1I6FA 1P0AA 1L4VA 2B68A 1N4NA 1B3CA 1ZFUA 1JZBA 1MYNA 2LT8A 1NH5A 4CQKA 1NPIA 1C56A 4UJ0A 1LQHA 1SN1A 1BRZA 1GPSA 1C55A 1B7DA 1KV0A 1TI5A 1BMRA 2KBKA 2LY5A 1I2UA 4HE7A 1GPTA 1T7BA 1ZVGA 1I2VA 1LQIA 1SNBA 1VNBA 3E7UX 1CHZA 1BCGA 2MZ0A 1ZYVA 1T1TA 2LJMA 2GL1A 2LKBA 2ASCA 2N2QA 5KK4A 2KBHA 1AHOA 1DQ7A 1SEGA 4HHFA 2I61A 1VNAA 1PTXA 2NY8X 1JXCA 1CN2A 1T7EA 1PE4A 4AB0A 2ATBA 2LY6A 1JKZA 1WT7A 2LJ7A 2BRZA 2A7TA 1T7AA 2YBRC 2M8BB 2KJAA 1SN4A 4V1DC 2KBJA 4AAZA 2SN3A 1ZYWA 2N2RA 2E3GA 2KSKA 1WWNA 4AEIA 1NRAA 2N69A 1WMTA 1P00A 1FH3A 3PSMA 1AYJA 1NE5A 2NY9X 1ICAA 2KPYA 2LR3A 5CY0A 2KGQA 1OMYA 1I6GA 2E0HA 1JZAA
chains in the Genus database with same CATH superfamily
3CW4A 2BUPA 3E7RL 1LQQA 1ZVEA 3QFUA 5AQYA 1HJOA 1DJTA 2N66A 1ZUTA 3CQXA 1OZZA 3BK3C 5FPNA 1BK8A 1ZU3A 2QW9A 3LDOA 3LDNA 4KBOA 4KYPA 1NRBA 2E88A 2QXLA 3LDLA 4H5NA 1K8BA 3GL1A 1ATSA 2KYQA 2B3CA 2LN8A 5AQGA 2E2FA 2E3FA 1T0ZA 5BPLA 2LI7A 2YC1C 3KC6A 1PX9A 2YEOA 1ATRA 1MR4A 1I6FA 1QQNA 1P0AA 3AY9A 1L4VA 1NGDA 2B68A 1DKGD 3KHWA 3D2EA 1N4NA 1NGFA 1B3CA 1ZFUA 5EVZA 3L4IA 2K35A 5AQJA 1JZBA 1MYNA 5AQKA 4H5VA 5AQQA 2LT8A 1S3XA 1NGJA 1NH5A 4CQKA 1NPIA 1C56A 2QWRA 5AQUA 4UJ0A 1LQHA 1NGGA 5FPDA 3KOWA 1SN1A 5FPEA 1BRZA 5EX5A 2JDQD 3GKUA 3C7NB 4H5RA 5EXWA 1GPSA 5AQNA 1QQOA 2V7ZA 3D2FA 3FZFA 4H5TA 3I33A 5AQOA 5AQHA 1C55A 1B7DA 1KV0A 1TI5A 3ATVA 5AQVA 2KBKA 1BMRA 4GNIA 2LY5A 5F0XA 2D56A 3QFPA 5BN9A 1I2UA 4HE7A 1GPTA 2QWPA 1T7BA 1ZVGA 2QWMA 2QWLA 3GDQA 1I2VA 5BPNA 1LQIA 2KHOA 3LDQA 4H5WA 1SNBA 1NGEA 4UAFE 5F1XA 3KOYA 1VNBA 3KOXA 2YILA 4FL9A 3E7UX 1CHZA 4IO8A 5EY4A 1BCGA 3KP1A 5AQFA 2MZ0A 1ZYVA 3IUCA 1NGIA 1T1TA 2GL1A 2LJMA 3M3ZA 5AQSA 5AQXA 2LKBA 2ASCA 2N2QA 5KK4A 1NGBA 1AHOA 2KBHA 3SF4D 1DQ7A 5BPMA 3FZHA 2QWOA 4FSVA 3FZLA 1SEGA 3D2EB 3KP0A 4HHFA 2I61A 3JXUA 3QI7A 1VNAA 1YUWA 1PTXA 2NY8X 1JXCA 5FPMA 1CN2A 3KOZA 1T7EA 3ATUA 1PE4A 2YIOA 4UADE 2ATBA 1KAXA 1NGHA 2LY6A 3A8YA 3L56A 1XRSB 1WT7A 2LJ7A 1JKZA 2BRZA 4UAEF 2QWQA 3HSCA 2A7TA 1T7AA 2YBRC 2M8BB 3LDPA 5AR0A 2KJAA 4AB0A 1SN4A 4V1DC 2KBJA 4AAZA 2SN3A 1ZYWA 5AQMA 3R2VA 2N2RA 5AQTA 1KAYA 3D2FB 2E3GA 5AQRA 5AQIA 2KSKA 2MN5A 5AQLA 2G2KA 1WWNA 4AEIA 1NRAA 2QWNA 1HPMA 4HWIA 1POIA 2N69A 1UGLA 3FZMA 3FE1A 3L6QA 1BUPA 1WMTA 1P00A 2MBKA 1FH3A 5AQZA 5BN8A 1NGAA 1BA0A 3PSMA 1QQMA 1AYJA 2GMOA 2YIPA 5AQPA 1KAZA 1NE5A 2NY9X 1ICAA 2KPYA 2LR3A 3C7NA 5F2RA 5CY0A 2KGQA 1OMYA 3FZKA 5AQWA 2E8AA 1I6GA 1BA1A 2E0HA 3QMLA 2VY6A 1JZAA 3KVGA 1HX1A 1NGCA
chains in the Genus database with same CATH topology
3E7RL 1LQQA 1ZVEA 1DJTA 2N66A 1ZUTA 1OZZA 1BK8A 1ZU3A 4KYPA 1NRBA 2KYQA 2B3CA 2E3FA 1T0ZA 2LI7A 2YC1C 1PX9A 2YEOA 1MR4A 1I6FA 1P0AA 1L4VA 2B68A 1N4NA 1B3CA 1ZFUA 1JZBA 1MYNA 2LT8A 1NH5A 4CQKA 1NPIA 1C56A 4UJ0A 1LQHA 1SN1A 1BRZA 1GPSA 1C55A 1B7DA 1KV0A 1TI5A 1BMRA 2KBKA 2LY5A 1I2UA 4HE7A 1GPTA 1T7BA 1ZVGA 1I2VA 1LQIA 1SNBA 1VNBA 3E7UX 1CHZA 1BCGA 2MZ0A 1ZYVA 1T1TA 2LJMA 2GL1A 2LKBA 2ASCA 2N2QA 5KK4A 2KBHA 1AHOA 1DQ7A 1SEGA 4HHFA 2I61A 1VNAA 1PTXA 2NY8X 1JXCA 1CN2A 1T7EA 1PE4A 4AB0A 2ATBA 2LY6A 1JKZA 1WT7A 2LJ7A 2BRZA 2A7TA 1T7AA 2YBRC 2M8BB 2KJAA 1SN4A 4V1DC 2KBJA 4AAZA 2SN3A 1ZYWA 2N2RA 2E3GA 2KSKA 1WWNA 4AEIA 1NRAA 2N69A 1WMTA 1P00A 1FH3A 3PSMA 1AYJA 1NE5A 2NY9X 1ICAA 2KPYA 2LR3A 5CY0A 2KGQA 1OMYA 1I6GA 2E0HA 1JZAA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3E7R L;  1LQQ A;  1ZVE A;  1DJT A;  2N66 A;  1ZUT A;  1OZZ A;  1BK8 A;  1ZU3 A;  4KYP A;  1NRB A;  2KYQ A;  2B3C A;  2E3F A;  1T0Z A;  2LI7 A;  2YC1 C;  1PX9 A;  2YEO A;  1MR4 A;  1I6F A;  1P0A A;  1L4V A;  2B68 A;  1N4N A;  1B3C A;  1ZFU A;  1JZB A;  1MYN A;  2LT8 A;  1NH5 A;  4CQK A;  1NPI A;  1C56 A;  4UJ0 A;  1LQH A;  1SN1 A;  1BRZ A;  1GPS A;  1C55 A;  1B7D A;  1KV0 A;  1TI5 A;  1BMR A;  2KBK A;  2LY5 A;  1I2U A;  4HE7 A;  1GPT A;  1T7B A;  1ZVG A;  1I2V A;  1LQI A;  1SNB A;  1VNB A;  3E7U X;  1CHZ A;  1BCG A;  2MZ0 A;  1ZYV A;  1T1T A;  2LJM A;  2GL1 A;  2LKB A;  2ASC A;  2N2Q A;  5KK4 A;  2KBH A;  1AHO A;  1DQ7 A;  1SEG A;  4HHF A;  2I61 A;  1VNA A;  1PTX A;  2NY8 X;  1JXC A;  1CN2 A;  1T7E A;  1PE4 A;  4AB0 A;  2ATB A;  2LY6 A;  1JKZ A;  1WT7 A;  2LJ7 A;  2BRZ A;  2A7T A;  1T7A A;  2YBR C;  2M8B B;  2KJA A;  1SN4 A;  4V1D C;  2KBJ A;  4AAZ A;  2SN3 A;  1ZYW A;  2N2R A;  2E3G A;  2KSK A;  1WWN A;  4AEI A;  1NRA A;  2N69 A;  1WMT A;  1P00 A;  1FH3 A;  3PSM A;  1AYJ A;  1NE5 A;  2NY9 X;  1ICA A;  2KPY A;  2LR3 A;  5CY0 A;  2KGQ A;  1OMY A;  1I6G A;  2E0H A;  1JZA A; 
#chains in the Genus database with same CATH topology
 3CW4 A;  2BUP A;  3E7R L;  1LQQ A;  1ZVE A;  3QFU A;  5AQY A;  1HJO A;  1DJT A;  2N66 A;  1ZUT A;  3CQX A;  1OZZ A;  3BK3 C;  5FPN A;  1BK8 A;  1ZU3 A;  2QW9 A;  3LDO A;  3LDN A;  4KBO A;  4KYP A;  1NRB A;  2E88 A;  2QXL A;  3LDL A;  4H5N A;  1K8B A;  3GL1 A;  1ATS A;  2KYQ A;  2B3C A;  2LN8 A;  5AQG A;  2E2F A;  2E3F A;  1T0Z A;  5BPL A;  2LI7 A;  2YC1 C;  3KC6 A;  1PX9 A;  2YEO A;  1ATR A;  1MR4 A;  1I6F A;  1QQN A;  1P0A A;  3AY9 A;  1L4V A;  1NGD A;  2B68 A;  1DKG D;  3KHW A;  3D2E A;  1N4N A;  1NGF A;  1B3C A;  1ZFU A;  5EVZ A;  3L4I A;  2K35 A;  5AQJ A;  1JZB A;  1MYN A;  5AQK A;  4H5V A;  5AQQ A;  2LT8 A;  1S3X A;  1NGJ A;  1NH5 A;  4CQK A;  1NPI A;  1C56 A;  2QWR A;  5AQU A;  4UJ0 A;  1LQH A;  1NGG A;  5FPD A;  3KOW A;  1SN1 A;  5FPE A;  1BRZ A;  5EX5 A;  2JDQ D;  3GKU A;  3C7N B;  4H5R A;  5EXW A;  1GPS A;  5AQN A;  1QQO A;  2V7Z A;  3D2F A;  3FZF A;  4H5T A;  3I33 A;  5AQO A;  5AQH A;  1C55 A;  1B7D A;  1KV0 A;  1TI5 A;  3ATV A;  5AQV A;  2KBK A;  1BMR A;  4GNI A;  2LY5 A;  5F0X A;  2D56 A;  3QFP A;  5BN9 A;  1I2U A;  4HE7 A;  1GPT A;  2QWP A;  1T7B A;  1ZVG A;  2QWM A;  2QWL A;  3GDQ A;  1I2V A;  5BPN A;  1LQI A;  2KHO A;  3LDQ A;  4H5W A;  1SNB A;  1NGE A;  4UAF E;  5F1X A;  3KOY A;  1VNB A;  3KOX A;  2YIL A;  4FL9 A;  3E7U X;  1CHZ A;  4IO8 A;  5EY4 A;  1BCG A;  3KP1 A;  5AQF A;  2MZ0 A;  1ZYV A;  3IUC A;  1NGI A;  1T1T A;  2GL1 A;  2LJM A;  3M3Z A;  5AQS A;  5AQX A;  2LKB A;  2ASC A;  2N2Q A;  5KK4 A;  1NGB A;  1AHO A;  2KBH A;  3SF4 D;  1DQ7 A;  5BPM A;  3FZH A;  2QWO A;  4FSV A;  3FZL A;  1SEG A;  3D2E B;  3KP0 A;  4HHF A;  2I61 A;  3JXU A;  3QI7 A;  1VNA A;  1YUW A;  1PTX A;  2NY8 X;  1JXC A;  5FPM A;  1CN2 A;  3KOZ A;  1T7E A;  3ATU A;  1PE4 A;  2YIO A;  4UAD E;  2ATB A;  1KAX A;  1NGH A;  2LY6 A;  3A8Y A;  3L56 A;  1XRS B;  1WT7 A;  2LJ7 A;  1JKZ A;  2BRZ A;  4UAE F;  2QWQ A;  3HSC A;  2A7T A;  1T7A A;  2YBR C;  2M8B B;  3LDP A;  5AR0 A;  2KJA A;  4AB0 A;  1SN4 A;  4V1D C;  2KBJ A;  4AAZ A;  2SN3 A;  1ZYW A;  5AQM A;  3R2V A;  2N2R A;  5AQT A;  1KAY A;  3D2F B;  2E3G A;  5AQR A;  5AQI A;  2KSK A;  2MN5 A;  5AQL A;  2G2K A;  1WWN A;  4AEI A;  1NRA A;  2QWN A;  1HPM A;  4HWI A;  1POI A;  2N69 A;  1UGL A;  3FZM A;  3FE1 A;  3L6Q A;  1BUP A;  1WMT A;  1P00 A;  2MBK A;  1FH3 A;  5AQZ A;  5BN8 A;  1NGA A;  1BA0 A;  3PSM A;  1QQM A;  1AYJ A;  2GMO A;  2YIP A;  5AQP A;  1KAZ A;  1NE5 A;  2NY9 X;  1ICA A;  2KPY A;  2LR3 A;  3C7N A;  5F2R A;  5CY0 A;  2KGQ A;  1OMY A;  3FZK A;  5AQW A;  2E8A A;  1I6G A;  1BA1 A;  2E0H A;  3QML A;  2VY6 A;  1JZA A;  3KVG A;  1HX1 A;  1NGC A; 
#chains in the Genus database with same CATH homology
 3E7R L;  1LQQ A;  1ZVE A;  1DJT A;  2N66 A;  1ZUT A;  1OZZ A;  1BK8 A;  1ZU3 A;  4KYP A;  1NRB A;  2KYQ A;  2B3C A;  2E3F A;  1T0Z A;  2LI7 A;  2YC1 C;  1PX9 A;  2YEO A;  1MR4 A;  1I6F A;  1P0A A;  1L4V A;  2B68 A;  1N4N A;  1B3C A;  1ZFU A;  1JZB A;  1MYN A;  2LT8 A;  1NH5 A;  4CQK A;  1NPI A;  1C56 A;  4UJ0 A;  1LQH A;  1SN1 A;  1BRZ A;  1GPS A;  1C55 A;  1B7D A;  1KV0 A;  1TI5 A;  1BMR A;  2KBK A;  2LY5 A;  1I2U A;  4HE7 A;  1GPT A;  1T7B A;  1ZVG A;  1I2V A;  1LQI A;  1SNB A;  1VNB A;  3E7U X;  1CHZ A;  1BCG A;  2MZ0 A;  1ZYV A;  1T1T A;  2LJM A;  2GL1 A;  2LKB A;  2ASC A;  2N2Q A;  5KK4 A;  2KBH A;  1AHO A;  1DQ7 A;  1SEG A;  4HHF A;  2I61 A;  1VNA A;  1PTX A;  2NY8 X;  1JXC A;  1CN2 A;  1T7E A;  1PE4 A;  4AB0 A;  2ATB A;  2LY6 A;  1JKZ A;  1WT7 A;  2LJ7 A;  2BRZ A;  2A7T A;  1T7A A;  2YBR C;  2M8B B;  2KJA A;  1SN4 A;  4V1D C;  2KBJ A;  4AAZ A;  2SN3 A;  1ZYW A;  2N2R A;  2E3G A;  2KSK A;  1WWN A;  4AEI A;  1NRA A;  2N69 A;  1WMT A;  1P00 A;  1FH3 A;  3PSM A;  1AYJ A;  1NE5 A;  2NY9 X;  1ICA A;  2KPY A;  2LR3 A;  5CY0 A;  2KGQ A;  1OMY A;  1I6G A;  2E0H A;  1JZA A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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