5CY0A

Total chemical synthesis, covalent structure verification, and x-ray structure of bioactive ts3 toxin by racemic protein crystallography
Total Genus 16
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
16
sequence length
63
structure length
63
Chain Sequence
KKDGYPVEYDNCAYICWNYDNAYCDKLCKDKKADSGYCYWVHILCYCYGLPDSEPTKTNGKCK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Elucidation of the Covalent and Tertiary Structures of Biologically Active Ts3 Toxin.
pubmed doi rcsb
molecule tags Toxin
molecule keywords Ts3 Toxin
total genus 16
structure length 63
sequence length 63
ec nomenclature
pdb deposition date 2015-07-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00537 Toxin_3 Scorpion toxin-like domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.30.10 Alpha Beta 2-Layer Sandwich Defensin A-like Knottin, scorpion toxin-like 5cy0A00
1BRZA 2YC1C 1ZU3A 1CN2A 1JZAA 1JXCA 2KBKA 1I2UA 3E7UX 2E0HA 5CY0A 1L4VA 1SEGA 2LJMA 1I2VA 2N2QA 1SN1A 4AAZA 1AYJA 4KYPA 2LI7A 4CQKA 1T1TA 1KV0A 1JKZA 1B7DA 1PX9A 2M8BB 4HE7A 2LY6A 1VNBA 1T7AA 1GPTA 1ZYWA 2NY8X 1AHOA 2KBHA 1ZUTA 1ICAA 2ATBA 1VNAA 2E3FA 1NRAA 1OMYA 1BMRA 2NY9X 3PSMA 1N4NA 1ZFUA 2LJ7A 2YBRC 4AEIA 1GPSA 5KK4A 4AB0A 3E7RL 2N69A 1C56A 1SNBA 2N66A 4V1DC 1FH3A 1JZBA 1DQ7A 2MZ0A 2LY5A 1P00A 2B3CA 1WT7A 2KPYA 2KJAA 1NE5A 1PE4A 1SN4A 2ASCA 1B3CA 1T7BA 2LR3A 4UJ0A 1DJTA 1C55A 2LT8A 2I61A 1T7EA 2YEOA 1CHZA 2B68A 2SN3A 2E3GA 1BK8A 1BCGA 1NPIA 2GL1A 1P0AA 1ZVEA 1TI5A 1WWNA 2BRZA 1T0ZA 2A7TA 1PTXA 4HHFA 1NRBA 1LQHA 2LKBA 1MR4A 1MYNA 2KGQA 2KBJA 1ZYVA 1I6FA 2KYQA 1I6GA 2N2RA 2KSKA 1OZZA 1LQIA 1NH5A 1LQQA 1ZVGA 1WMTA
chains in the Genus database with same CATH superfamily
1ATSA 1BRZA 5BPLA 2YC1C 1ZU3A 2E2FA 1YUWA 3CQXA 5AQRA 1UGLA 2QWRA 1NGGA 4UADE 5FPEA 1JZAA 2GMOA 1CN2A 3LDPA 2YIOA 1JXCA 3FZKA 2KBKA 3L4IA 1I2UA 3C7NA 2E0HA 2QWMA 3E7UX 5AQGA 5CY0A 4H5TA 1L4VA 1SEGA 2LJMA 1NGCA 1QQMA 1I2VA 2N2QA 5AQIA 1SN1A 1XRSB 1NGFA 5AQOA 5AQKA 4AAZA 1AYJA 5EX5A 4KYPA 2LI7A 5AQXA 1T1TA 4CQKA 2K35A 1KV0A 1JKZA 3I33A 1B7DA 2QXLA 1NGDA 1NGEA 1PX9A 2D56A 5BN8A 5F1XA 5AQHA 3ATVA 2M8BB 3CW4A 5AQUA 4HE7A 2LY6A 1VNBA 1T7AA 3LDNA 3QMLA 1ZYWA 5AR0A 2NY8X 1GPTA 1KAYA 2QWNA 1QQNA 1HX1A 1AHOA 3L56A 1QQOA 2KBHA 1ZUTA 1ICAA 2ATBA 1DKGD 1VNAA 4FSVA 5AQYA 5FPNA 5EVZA 4H5VA 2E3FA 1NRAA 1OMYA 3D2FA 5AQZA 3AY9A 1BMRA 2NY9X 3KHWA 3PSMA 2VY6A 1NGAA 1N4NA 2YIPA 1ZFUA 1K8BA 5FPMA 2LJ7A 4KBOA 5AQMA 2YBRC 2YILA 2BUPA 3FE1A 4FL9A 4AEIA 1GPSA 3GL1A 3KOZA 5AQPA 3D2FB 5KK4A 3QI7A 3FZMA 1HPMA 2MN5A 3JXUA 4AB0A 2LN8A 3D2EB 2N69A 3E7RL 5AQSA 1C56A 1SNBA 2N66A 2E88A 2QWQA 4V1DC 2JDQD 5F0XA 1FH3A 5FPDA 1JZBA 1DQ7A 2MBKA 2MZ0A 3KP0A 2QWLA 3KVGA 5EXWA 2LY5A 1P00A 2B3CA 1WT7A 3KOXA 3LDOA 2KPYA 3KC6A 4GNIA 1NGIA 3D2EA 2KJAA 3M3ZA 1NE5A 1PE4A 1SN4A 2ASCA 4UAFE 2QWOA 1B3CA 1KAZA 1T7BA 2LR3A 3GKUA 4H5NA 3R2VA 5AQNA 4UJ0A 1DJTA 3A8YA 1C55A 5BN9A 2LT8A 3KOYA 2I61A 4H5RA 2G2KA 1POIA 1HJOA 5AQTA 1BUPA 1T7EA 5AQVA 4UAEF 2V7ZA 3QFUA 2YEOA 1NGJA 1CHZA 2B68A 2SN3A 2E3GA 3L6QA 1BK8A 1BCGA 2QWPA 1NPIA 3HSCA 3BK3C 3IUCA 1S3XA 2GL1A 2KHOA 4HWIA 5AQQA 3FZLA 1P0AA 1ZVEA 3KOWA 1ATRA 1TI5A 1WWNA 2BRZA 3GDQA 3LDLA 2QW9A 3KP1A 1T0ZA 2A7TA 3QFPA 5EY4A 3LDQA 3ATUA 1PTXA 4HHFA 1NGHA 3SF4D 1NRBA 3FZHA 1LQHA 2LKBA 1MR4A 1MYNA 2KGQA 5AQFA 2KBJA 5AQWA 1ZYVA 1KAXA 1I6FA 2KYQA 2E8AA 1I6GA 5BPNA 1BA1A 4H5WA 4IO8A 5F2RA 2N2RA 2KSKA 3FZFA 5AQJA 1OZZA 1LQIA 1NGBA 5BPMA 1NH5A 1LQQA 3C7NB 1BA0A 1ZVGA 1WMTA 5AQLA
chains in the Genus database with same CATH topology
1BRZA 2YC1C 1ZU3A 1CN2A 1JZAA 1JXCA 2KBKA 1I2UA 3E7UX 2E0HA 5CY0A 1L4VA 1SEGA 2LJMA 1I2VA 2N2QA 1SN1A 4AAZA 1AYJA 4KYPA 2LI7A 4CQKA 1T1TA 1KV0A 1JKZA 1B7DA 1PX9A 2M8BB 4HE7A 2LY6A 1VNBA 1T7AA 1GPTA 1ZYWA 2NY8X 1AHOA 2KBHA 1ZUTA 1ICAA 2ATBA 1VNAA 2E3FA 1NRAA 1OMYA 1BMRA 2NY9X 3PSMA 1N4NA 1ZFUA 2LJ7A 2YBRC 4AEIA 1GPSA 5KK4A 4AB0A 3E7RL 2N69A 1C56A 1SNBA 2N66A 4V1DC 1FH3A 1JZBA 1DQ7A 2MZ0A 2LY5A 1P00A 2B3CA 1WT7A 2KPYA 2KJAA 1NE5A 1PE4A 1SN4A 2ASCA 1B3CA 1T7BA 2LR3A 4UJ0A 1DJTA 1C55A 2LT8A 2I61A 1T7EA 2YEOA 1CHZA 2B68A 2SN3A 2E3GA 1BK8A 1BCGA 1NPIA 2GL1A 1P0AA 1ZVEA 1TI5A 1WWNA 2BRZA 1T0ZA 2A7TA 1PTXA 4HHFA 1NRBA 1LQHA 2LKBA 1MR4A 1MYNA 2KGQA 2KBJA 1ZYVA 1I6FA 2KYQA 1I6GA 2N2RA 2KSKA 1OZZA 1LQIA 1NH5A 1LQQA 1ZVGA 1WMTA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1BRZ A;  2YC1 C;  1ZU3 A;  1CN2 A;  1JZA A;  1JXC A;  2KBK A;  1I2U A;  3E7U X;  2E0H A;  5CY0 A;  1L4V A;  1SEG A;  2LJM A;  1I2V A;  2N2Q A;  1SN1 A;  4AAZ A;  1AYJ A;  4KYP A;  2LI7 A;  4CQK A;  1T1T A;  1KV0 A;  1JKZ A;  1B7D A;  1PX9 A;  2M8B B;  4HE7 A;  2LY6 A;  1VNB A;  1T7A A;  1GPT A;  1ZYW A;  2NY8 X;  1AHO A;  2KBH A;  1ZUT A;  1ICA A;  2ATB A;  1VNA A;  2E3F A;  1NRA A;  1OMY A;  1BMR A;  2NY9 X;  3PSM A;  1N4N A;  1ZFU A;  2LJ7 A;  2YBR C;  4AEI A;  1GPS A;  5KK4 A;  4AB0 A;  3E7R L;  2N69 A;  1C56 A;  1SNB A;  2N66 A;  4V1D C;  1FH3 A;  1JZB A;  1DQ7 A;  2MZ0 A;  2LY5 A;  1P00 A;  2B3C A;  1WT7 A;  2KPY A;  2KJA A;  1NE5 A;  1PE4 A;  1SN4 A;  2ASC A;  1B3C A;  1T7B A;  2LR3 A;  4UJ0 A;  1DJT A;  1C55 A;  2LT8 A;  2I61 A;  1T7E A;  2YEO A;  1CHZ A;  2B68 A;  2SN3 A;  2E3G A;  1BK8 A;  1BCG A;  1NPI A;  2GL1 A;  1P0A A;  1ZVE A;  1TI5 A;  1WWN A;  2BRZ A;  1T0Z A;  2A7T A;  1PTX A;  4HHF A;  1NRB A;  1LQH A;  2LKB A;  1MR4 A;  1MYN A;  2KGQ A;  2KBJ A;  1ZYV A;  1I6F A;  2KYQ A;  1I6G A;  2N2R A;  2KSK A;  1OZZ A;  1LQI A;  1NH5 A;  1LQQ A;  1ZVG A;  1WMT A; 
#chains in the Genus database with same CATH topology
 1ATS A;  1BRZ A;  5BPL A;  2YC1 C;  1ZU3 A;  2E2F A;  1YUW A;  3CQX A;  5AQR A;  1UGL A;  2QWR A;  1NGG A;  4UAD E;  5FPE A;  1JZA A;  2GMO A;  1CN2 A;  3LDP A;  2YIO A;  1JXC A;  3FZK A;  2KBK A;  3L4I A;  1I2U A;  3C7N A;  2E0H A;  2QWM A;  3E7U X;  5AQG A;  5CY0 A;  4H5T A;  1L4V A;  1SEG A;  2LJM A;  1NGC A;  1QQM A;  1I2V A;  2N2Q A;  5AQI A;  1SN1 A;  1XRS B;  1NGF A;  5AQO A;  5AQK A;  4AAZ A;  1AYJ A;  5EX5 A;  4KYP A;  2LI7 A;  5AQX A;  1T1T A;  4CQK A;  2K35 A;  1KV0 A;  1JKZ A;  3I33 A;  1B7D A;  2QXL A;  1NGD A;  1NGE A;  1PX9 A;  2D56 A;  5BN8 A;  5F1X A;  5AQH A;  3ATV A;  2M8B B;  3CW4 A;  5AQU A;  4HE7 A;  2LY6 A;  1VNB A;  1T7A A;  3LDN A;  3QML A;  1ZYW A;  5AR0 A;  2NY8 X;  1GPT A;  1KAY A;  2QWN A;  1QQN A;  1HX1 A;  1AHO A;  3L56 A;  1QQO A;  2KBH A;  1ZUT A;  1ICA A;  2ATB A;  1DKG D;  1VNA A;  4FSV A;  5AQY A;  5FPN A;  5EVZ A;  4H5V A;  2E3F A;  1NRA A;  1OMY A;  3D2F A;  5AQZ A;  3AY9 A;  1BMR A;  2NY9 X;  3KHW A;  3PSM A;  2VY6 A;  1NGA A;  1N4N A;  2YIP A;  1ZFU A;  1K8B A;  5FPM A;  2LJ7 A;  4KBO A;  5AQM A;  2YBR C;  2YIL A;  2BUP A;  3FE1 A;  4FL9 A;  4AEI A;  1GPS A;  3GL1 A;  3KOZ A;  5AQP A;  3D2F B;  5KK4 A;  3QI7 A;  3FZM A;  1HPM A;  2MN5 A;  3JXU A;  4AB0 A;  2LN8 A;  3D2E B;  2N69 A;  3E7R L;  5AQS A;  1C56 A;  1SNB A;  2N66 A;  2E88 A;  2QWQ A;  4V1D C;  2JDQ D;  5F0X A;  1FH3 A;  5FPD A;  1JZB A;  1DQ7 A;  2MBK A;  2MZ0 A;  3KP0 A;  2QWL A;  3KVG A;  5EXW A;  2LY5 A;  1P00 A;  2B3C A;  1WT7 A;  3KOX A;  3LDO A;  2KPY A;  3KC6 A;  4GNI A;  1NGI A;  3D2E A;  2KJA A;  3M3Z A;  1NE5 A;  1PE4 A;  1SN4 A;  2ASC A;  4UAF E;  2QWO A;  1B3C A;  1KAZ A;  1T7B A;  2LR3 A;  3GKU A;  4H5N A;  3R2V A;  5AQN A;  4UJ0 A;  1DJT A;  3A8Y A;  1C55 A;  5BN9 A;  2LT8 A;  3KOY A;  2I61 A;  4H5R A;  2G2K A;  1POI A;  1HJO A;  5AQT A;  1BUP A;  1T7E A;  5AQV A;  4UAE F;  2V7Z A;  3QFU A;  2YEO A;  1NGJ A;  1CHZ A;  2B68 A;  2SN3 A;  2E3G A;  3L6Q A;  1BK8 A;  1BCG A;  2QWP A;  1NPI A;  3HSC A;  3BK3 C;  3IUC A;  1S3X A;  2GL1 A;  2KHO A;  4HWI A;  5AQQ A;  3FZL A;  1P0A A;  1ZVE A;  3KOW A;  1ATR A;  1TI5 A;  1WWN A;  2BRZ A;  3GDQ A;  3LDL A;  2QW9 A;  3KP1 A;  1T0Z A;  2A7T A;  3QFP A;  5EY4 A;  3LDQ A;  3ATU A;  1PTX A;  4HHF A;  1NGH A;  3SF4 D;  1NRB A;  3FZH A;  1LQH A;  2LKB A;  1MR4 A;  1MYN A;  2KGQ A;  5AQF A;  2KBJ A;  5AQW A;  1ZYV A;  1KAX A;  1I6F A;  2KYQ A;  2E8A A;  1I6G A;  5BPN A;  1BA1 A;  4H5W A;  4IO8 A;  5F2R A;  2N2R A;  2KSK A;  3FZF A;  5AQJ A;  1OZZ A;  1LQI A;  1NGB A;  5BPM A;  1NH5 A;  1LQQ A;  3C7N B;  1BA0 A;  1ZVG A;  1WMT A;  5AQL A; 
#chains in the Genus database with same CATH homology
 1BRZ A;  2YC1 C;  1ZU3 A;  1CN2 A;  1JZA A;  1JXC A;  2KBK A;  1I2U A;  3E7U X;  2E0H A;  5CY0 A;  1L4V A;  1SEG A;  2LJM A;  1I2V A;  2N2Q A;  1SN1 A;  4AAZ A;  1AYJ A;  4KYP A;  2LI7 A;  4CQK A;  1T1T A;  1KV0 A;  1JKZ A;  1B7D A;  1PX9 A;  2M8B B;  4HE7 A;  2LY6 A;  1VNB A;  1T7A A;  1GPT A;  1ZYW A;  2NY8 X;  1AHO A;  2KBH A;  1ZUT A;  1ICA A;  2ATB A;  1VNA A;  2E3F A;  1NRA A;  1OMY A;  1BMR A;  2NY9 X;  3PSM A;  1N4N A;  1ZFU A;  2LJ7 A;  2YBR C;  4AEI A;  1GPS A;  5KK4 A;  4AB0 A;  3E7R L;  2N69 A;  1C56 A;  1SNB A;  2N66 A;  4V1D C;  1FH3 A;  1JZB A;  1DQ7 A;  2MZ0 A;  2LY5 A;  1P00 A;  2B3C A;  1WT7 A;  2KPY A;  2KJA A;  1NE5 A;  1PE4 A;  1SN4 A;  2ASC A;  1B3C A;  1T7B A;  2LR3 A;  4UJ0 A;  1DJT A;  1C55 A;  2LT8 A;  2I61 A;  1T7E A;  2YEO A;  1CHZ A;  2B68 A;  2SN3 A;  2E3G A;  1BK8 A;  1BCG A;  1NPI A;  2GL1 A;  1P0A A;  1ZVE A;  1TI5 A;  1WWN A;  2BRZ A;  1T0Z A;  2A7T A;  1PTX A;  4HHF A;  1NRB A;  1LQH A;  2LKB A;  1MR4 A;  1MYN A;  2KGQ A;  2KBJ A;  1ZYV A;  1I6F A;  2KYQ A;  1I6G A;  2N2R A;  2KSK A;  1OZZ A;  1LQI A;  1NH5 A;  1LQQ A;  1ZVG A;  1WMT A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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