5CY0A

Total chemical synthesis, covalent structure verification, and x-ray structure of bioactive ts3 toxin by racemic protein crystallography
Total Genus 16
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
16
sequence length
63
structure length
63
Chain Sequence
KKDGYPVEYDNCAYICWNYDNAYCDKLCKDKKADSGYCYWVHILCYCYGLPDSEPTKTNGKCK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Elucidation of the Covalent and Tertiary Structures of Biologically Active Ts3 Toxin.
pubmed doi rcsb
molecule tags Toxin
molecule keywords Ts3 Toxin
total genus 16
structure length 63
sequence length 63
ec nomenclature
pdb deposition date 2015-07-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00537 Toxin_3 Scorpion toxin-like domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.30.10 Alpha Beta 2-Layer Sandwich Defensin A-like Knottin, scorpion toxin-like 5cy0A00
2M8BB 1NH5A 2KGQA 2YC1C 2LT8A 2YBRC 1N4NA 2KPYA 1ZVEA 1L4VA 2LJMA 1SN1A 1T7BA 1I2UA 1LQIA 2LJ7A 4V1DC 1KV0A 4CQKA 1PX9A 1CHZA 1GPTA 4HE7A 2KBJA 1TI5A 1ZYVA 2LY6A 2B3CA 1SEGA 1I6FA 2YEOA 2E3GA 2NY9X 1SN4A 1WWNA 1B3CA 1C56A 1FH3A 5CY0A 2NY8X 3E7UX 1JXCA 1MYNA 1ZVGA 1PTXA 2A7TA 2E3FA 3E7RL 2LY5A 2N66A 1NPIA 1NE5A 1OZZA 1BRZA 4KYPA 4AEIA 1P0AA 1I6GA 1ZFUA 1T0ZA 5KK4A 2SN3A 2B68A 2N69A 1MR4A 1JKZA 1LQQA 1T7EA 1T7AA 2LKBA 1VNAA 3PSMA 1LQHA 2GL1A 1ZUTA 2KBKA 1I2VA 1BMRA 1JZAA 1T1TA 1ZYWA 2N2QA 2LR3A 2KBHA 2I61A 2LI7A 2KJAA 1ICAA 1AHOA 1BCGA 1CN2A 2KSKA 1PE4A 1VNBA 4HHFA 1JZBA 1NRAA 1NRBA 1ZU3A 4AAZA 2MZ0A 2KYQA 2N2RA 1WT7A 4AB0A 1P00A 1C55A 2ATBA 1DJTA 1DQ7A 1SNBA 1B7DA 1OMYA 4UJ0A 1BK8A 1AYJA 2ASCA 1GPSA 2BRZA 1WMTA 2E0HA
chains in the Genus database with same CATH superfamily
5AQVA 2M8BB 5AQIA 1NH5A 2KGQA 3C7NA 5FPEA 5AQXA 2KHOA 1NGCA 3QFPA 3D2EB 2YC1C 3KOXA 2LT8A 2YBRC 1N4NA 2KPYA 1ZVEA 5EXWA 1NGFA 4FL9A 1L4VA 3KC6A 2LJMA 2V7ZA 1SN1A 2QWRA 1T7BA 3GDQA 1NGEA 1I2UA 2QWNA 1LQIA 2LJ7A 4H5WA 4V1DC 1HJOA 1KV0A 1QQOA 3GKUA 1PX9A 5EX5A 2QWLA 3BK3C 4CQKA 5BN8A 3KOYA 1CHZA 1BA1A 1KAXA 1GPTA 3R2VA 4HE7A 2QWQA 2KBJA 5F0XA 3KVGA 1TI5A 1ZYVA 2LY6A 3QMLA 2QWPA 2B3CA 1SEGA 1I6FA 2YEOA 2E3GA 2NY9X 1SN4A 1WWNA 2JDQD 1C56A 3I33A 5AQMA 3GL1A 2MBKA 5CY0A 1B3CA 4UAFE 5EY4A 2QWOA 2NY8X 3LDQA 3E7UX 5AQYA 1JXCA 2GMOA 1MYNA 1ZVGA 1PTXA 2A7TA 3LDOA 2E3FA 3C7NB 3E7RL 5FPMA 2LY5A 2N66A 1NPIA 1NE5A 5AQPA 1OZZA 3A8YA 1FH3A 1BRZA 4HWIA 4KYPA 5AQKA 3L4IA 5AQRA 4AEIA 5AQNA 1P0AA 1NGAA 1I6GA 3LDNA 5FPNA 3HSCA 3KP0A 5AR0A 2K35A 1ZFUA 1T0ZA 5KK4A 5BN9A 2SN3A 2MN5A 2E2FA 2B68A 2E88A 1XRSB 2N69A 1MR4A 5F1XA 1JKZA 3IUCA 1DKGD 1LQQA 1T7EA 1NGHA 1BUPA 4KBOA 1T7AA 1NGJA 5EVZA 4UADE 3D2FA 5FPDA 2LKBA 1KAYA 1VNAA 3PSMA 1LQHA 2YIOA 2GL1A 1ZUTA 2D56A 3KOWA 3KP1A 3L56A 2BUPA 4H5NA 1QQNA 1K8BA 2G2KA 2YIPA 4IO8A 2KBKA 4FSVA 2QXLA 5BPNA 1I2VA 3M3ZA 1BMRA 3JXUA 5AQLA 5AQGA 1POIA 2LN8A 5AQJA 3FE1A 1HPMA 1JZAA 1T1TA 1NGIA 3ATUA 1ZYWA 2N2QA 2LR3A 3ATVA 2KBHA 2I61A 2LI7A 3QFUA 5AQSA 2KJAA 2QWMA 4H5TA 1ICAA 5AQQA 5AQWA 3CQXA 1AHOA 2VY6A 3LDPA 3D2EA 4H5VA 1S3XA 1NGDA 1BCGA 3AY9A 4H5RA 1CN2A 3FZMA 4UAEF 3FZLA 4GNIA 5AQTA 1HX1A 3FZKA 2KSKA 1PE4A 1VNBA 5AQZA 1NGBA 3D2FB 5AQHA 4HHFA 1JZBA 1QQMA 2QW9A 3L6QA 1NRAA 1NRBA 1ZU3A 5AQUA 5BPMA 4AAZA 2MZ0A 3LDLA 1ATSA 1YUWA 5BPLA 2KYQA 2N2RA 1WT7A 3CW4A 3KHWA 1P00A 3FZFA 5AQOA 4AB0A 1C55A 2ATBA 1DJTA 1DQ7A 3KOZA 1BA0A 1SNBA 1B7DA 1OMYA 3QI7A 4UJ0A 5AQFA 1BK8A 1AYJA 2ASCA 2E8AA 1ATRA 2YILA 5F2RA 1GPSA 1KAZA 1NGGA 2BRZA 1WMTA 2E0HA 1UGLA 3SF4D 3FZHA
chains in the Genus database with same CATH topology
2M8BB 1NH5A 2KGQA 2YC1C 2LT8A 2YBRC 1N4NA 2KPYA 1ZVEA 1L4VA 2LJMA 1SN1A 1T7BA 1I2UA 1LQIA 2LJ7A 4V1DC 1KV0A 4CQKA 1PX9A 1CHZA 1GPTA 4HE7A 2KBJA 1TI5A 1ZYVA 2LY6A 2B3CA 1SEGA 1I6FA 2YEOA 2E3GA 2NY9X 1SN4A 1WWNA 1B3CA 1C56A 1FH3A 5CY0A 2NY8X 3E7UX 1JXCA 1MYNA 1ZVGA 1PTXA 2A7TA 2E3FA 3E7RL 2LY5A 2N66A 1NPIA 1NE5A 1OZZA 1BRZA 4KYPA 4AEIA 1P0AA 1I6GA 1ZFUA 1T0ZA 5KK4A 2SN3A 2B68A 2N69A 1MR4A 1JKZA 1LQQA 1T7EA 1T7AA 2LKBA 1VNAA 3PSMA 1LQHA 2GL1A 1ZUTA 2KBKA 1I2VA 1BMRA 1JZAA 1T1TA 1ZYWA 2N2QA 2LR3A 2KBHA 2I61A 2LI7A 2KJAA 1ICAA 1AHOA 1BCGA 1CN2A 2KSKA 1PE4A 1VNBA 4HHFA 1JZBA 1NRAA 1NRBA 1ZU3A 4AAZA 2MZ0A 2KYQA 2N2RA 1WT7A 4AB0A 1P00A 1C55A 2ATBA 1DJTA 1DQ7A 1SNBA 1B7DA 1OMYA 4UJ0A 1BK8A 1AYJA 2ASCA 1GPSA 2BRZA 1WMTA 2E0HA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2M8B B;  1NH5 A;  2KGQ A;  2YC1 C;  2LT8 A;  2YBR C;  1N4N A;  2KPY A;  1ZVE A;  1L4V A;  2LJM A;  1SN1 A;  1T7B A;  1I2U A;  1LQI A;  2LJ7 A;  4V1D C;  1KV0 A;  4CQK A;  1PX9 A;  1CHZ A;  1GPT A;  4HE7 A;  2KBJ A;  1TI5 A;  1ZYV A;  2LY6 A;  2B3C A;  1SEG A;  1I6F A;  2YEO A;  2E3G A;  2NY9 X;  1SN4 A;  1WWN A;  1B3C A;  1C56 A;  1FH3 A;  5CY0 A;  2NY8 X;  3E7U X;  1JXC A;  1MYN A;  1ZVG A;  1PTX A;  2A7T A;  2E3F A;  3E7R L;  2LY5 A;  2N66 A;  1NPI A;  1NE5 A;  1OZZ A;  1BRZ A;  4KYP A;  4AEI A;  1P0A A;  1I6G A;  1ZFU A;  1T0Z A;  5KK4 A;  2SN3 A;  2B68 A;  2N69 A;  1MR4 A;  1JKZ A;  1LQQ A;  1T7E A;  1T7A A;  2LKB A;  1VNA A;  3PSM A;  1LQH A;  2GL1 A;  1ZUT A;  2KBK A;  1I2V A;  1BMR A;  1JZA A;  1T1T A;  1ZYW A;  2N2Q A;  2LR3 A;  2KBH A;  2I61 A;  2LI7 A;  2KJA A;  1ICA A;  1AHO A;  1BCG A;  1CN2 A;  2KSK A;  1PE4 A;  1VNB A;  4HHF A;  1JZB A;  1NRA A;  1NRB A;  1ZU3 A;  4AAZ A;  2MZ0 A;  2KYQ A;  2N2R A;  1WT7 A;  4AB0 A;  1P00 A;  1C55 A;  2ATB A;  1DJT A;  1DQ7 A;  1SNB A;  1B7D A;  1OMY A;  4UJ0 A;  1BK8 A;  1AYJ A;  2ASC A;  1GPS A;  2BRZ A;  1WMT A;  2E0H A; 
#chains in the Genus database with same CATH topology
 5AQV A;  2M8B B;  5AQI A;  1NH5 A;  2KGQ A;  3C7N A;  5FPE A;  5AQX A;  2KHO A;  1NGC A;  3QFP A;  3D2E B;  2YC1 C;  3KOX A;  2LT8 A;  2YBR C;  1N4N A;  2KPY A;  1ZVE A;  5EXW A;  1NGF A;  4FL9 A;  1L4V A;  3KC6 A;  2LJM A;  2V7Z A;  1SN1 A;  2QWR A;  1T7B A;  3GDQ A;  1NGE A;  1I2U A;  2QWN A;  1LQI A;  2LJ7 A;  4H5W A;  4V1D C;  1HJO A;  1KV0 A;  1QQO A;  3GKU A;  1PX9 A;  5EX5 A;  2QWL A;  3BK3 C;  4CQK A;  5BN8 A;  3KOY A;  1CHZ A;  1BA1 A;  1KAX A;  1GPT A;  3R2V A;  4HE7 A;  2QWQ A;  2KBJ A;  5F0X A;  3KVG A;  1TI5 A;  1ZYV A;  2LY6 A;  3QML A;  2QWP A;  2B3C A;  1SEG A;  1I6F A;  2YEO A;  2E3G A;  2NY9 X;  1SN4 A;  1WWN A;  2JDQ D;  1C56 A;  3I33 A;  5AQM A;  3GL1 A;  2MBK A;  5CY0 A;  1B3C A;  4UAF E;  5EY4 A;  2QWO A;  2NY8 X;  3LDQ A;  3E7U X;  5AQY A;  1JXC A;  2GMO A;  1MYN A;  1ZVG A;  1PTX A;  2A7T A;  3LDO A;  2E3F A;  3C7N B;  3E7R L;  5FPM A;  2LY5 A;  2N66 A;  1NPI A;  1NE5 A;  5AQP A;  1OZZ A;  3A8Y A;  1FH3 A;  1BRZ A;  4HWI A;  4KYP A;  5AQK A;  3L4I A;  5AQR A;  4AEI A;  5AQN A;  1P0A A;  1NGA A;  1I6G A;  3LDN A;  5FPN A;  3HSC A;  3KP0 A;  5AR0 A;  2K35 A;  1ZFU A;  1T0Z A;  5KK4 A;  5BN9 A;  2SN3 A;  2MN5 A;  2E2F A;  2B68 A;  2E88 A;  1XRS B;  2N69 A;  1MR4 A;  5F1X A;  1JKZ A;  3IUC A;  1DKG D;  1LQQ A;  1T7E A;  1NGH A;  1BUP A;  4KBO A;  1T7A A;  1NGJ A;  5EVZ A;  4UAD E;  3D2F A;  5FPD A;  2LKB A;  1KAY A;  1VNA A;  3PSM A;  1LQH A;  2YIO A;  2GL1 A;  1ZUT A;  2D56 A;  3KOW A;  3KP1 A;  3L56 A;  2BUP A;  4H5N A;  1QQN A;  1K8B A;  2G2K A;  2YIP A;  4IO8 A;  2KBK A;  4FSV A;  2QXL A;  5BPN A;  1I2V A;  3M3Z A;  1BMR A;  3JXU A;  5AQL A;  5AQG A;  1POI A;  2LN8 A;  5AQJ A;  3FE1 A;  1HPM A;  1JZA A;  1T1T A;  1NGI A;  3ATU A;  1ZYW A;  2N2Q A;  2LR3 A;  3ATV A;  2KBH A;  2I61 A;  2LI7 A;  3QFU A;  5AQS A;  2KJA A;  2QWM A;  4H5T A;  1ICA A;  5AQQ A;  5AQW A;  3CQX A;  1AHO A;  2VY6 A;  3LDP A;  3D2E A;  4H5V A;  1S3X A;  1NGD A;  1BCG A;  3AY9 A;  4H5R A;  1CN2 A;  3FZM A;  4UAE F;  3FZL A;  4GNI A;  5AQT A;  1HX1 A;  3FZK A;  2KSK A;  1PE4 A;  1VNB A;  5AQZ A;  1NGB A;  3D2F B;  5AQH A;  4HHF A;  1JZB A;  1QQM A;  2QW9 A;  3L6Q A;  1NRA A;  1NRB A;  1ZU3 A;  5AQU A;  5BPM A;  4AAZ A;  2MZ0 A;  3LDL A;  1ATS A;  1YUW A;  5BPL A;  2KYQ A;  2N2R A;  1WT7 A;  3CW4 A;  3KHW A;  1P00 A;  3FZF A;  5AQO A;  4AB0 A;  1C55 A;  2ATB A;  1DJT A;  1DQ7 A;  3KOZ A;  1BA0 A;  1SNB A;  1B7D A;  1OMY A;  3QI7 A;  4UJ0 A;  5AQF A;  1BK8 A;  1AYJ A;  2ASC A;  2E8A A;  1ATR A;  2YIL A;  5F2R A;  1GPS A;  1KAZ A;  1NGG A;  2BRZ A;  1WMT A;  2E0H A;  1UGL A;  3SF4 D;  3FZH A; 
#chains in the Genus database with same CATH homology
 2M8B B;  1NH5 A;  2KGQ A;  2YC1 C;  2LT8 A;  2YBR C;  1N4N A;  2KPY A;  1ZVE A;  1L4V A;  2LJM A;  1SN1 A;  1T7B A;  1I2U A;  1LQI A;  2LJ7 A;  4V1D C;  1KV0 A;  4CQK A;  1PX9 A;  1CHZ A;  1GPT A;  4HE7 A;  2KBJ A;  1TI5 A;  1ZYV A;  2LY6 A;  2B3C A;  1SEG A;  1I6F A;  2YEO A;  2E3G A;  2NY9 X;  1SN4 A;  1WWN A;  1B3C A;  1C56 A;  1FH3 A;  5CY0 A;  2NY8 X;  3E7U X;  1JXC A;  1MYN A;  1ZVG A;  1PTX A;  2A7T A;  2E3F A;  3E7R L;  2LY5 A;  2N66 A;  1NPI A;  1NE5 A;  1OZZ A;  1BRZ A;  4KYP A;  4AEI A;  1P0A A;  1I6G A;  1ZFU A;  1T0Z A;  5KK4 A;  2SN3 A;  2B68 A;  2N69 A;  1MR4 A;  1JKZ A;  1LQQ A;  1T7E A;  1T7A A;  2LKB A;  1VNA A;  3PSM A;  1LQH A;  2GL1 A;  1ZUT A;  2KBK A;  1I2V A;  1BMR A;  1JZA A;  1T1T A;  1ZYW A;  2N2Q A;  2LR3 A;  2KBH A;  2I61 A;  2LI7 A;  2KJA A;  1ICA A;  1AHO A;  1BCG A;  1CN2 A;  2KSK A;  1PE4 A;  1VNB A;  4HHF A;  1JZB A;  1NRA A;  1NRB A;  1ZU3 A;  4AAZ A;  2MZ0 A;  2KYQ A;  2N2R A;  1WT7 A;  4AB0 A;  1P00 A;  1C55 A;  2ATB A;  1DJT A;  1DQ7 A;  1SNB A;  1B7D A;  1OMY A;  4UJ0 A;  1BK8 A;  1AYJ A;  2ASC A;  1GPS A;  2BRZ A;  1WMT A;  2E0H A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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