1K8FA

Crystal structure of the human c-terminal cap1-adenylyl cyclase associated protein
Total Genus 47
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
47
sequence length
157
structure length
157
Chain Sequence
PAVLELEGKKWRVENQENVSNLVIEDTELKQVAYIYKCVNTTLQIKGKINSITVDNCKKLGLVFDDVVGIVEIINSKDVKVQVMGKVPTISINKTDGCHAYLSKNSLDCEIVSAKSSEMNVLIPTEGGDFNEFPVPEQFKTLWNGQKLVTTVTEIAG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Crystal structure of the actin binding domain of the cyclase-associated protein.
pubmed doi rcsb
molecule tags Unknown function
source organism Homo sapiens
molecule keywords ADENYLYL CYCLASE-ASSOCIATED PROTEIN
total genus 47
structure length 157
sequence length 157
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2001-10-24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.160.20.70 Mainly Beta 3 Solenoid Pectate Lyase C-like Pectate Lyase C-like 1k8fA00
2B0RA 1HF2A 2YUHA 3BH7B 2BX6A 3BH6B 1KQ5A 1K8FA 4V02C 1K4ZA
chains in the Genus database with same CATH superfamily
5DNSA 2NTQA 2X6WA 4OPWA 4XLFA 1QA3A 1DBOA 1KQ5A 1OGOX 2G0YA 2O6WA 1OFDA 2PYGA 4W8QA 4W8TA 1K5CA 4XNFA 1EE6A 1X0CA 1LLWA 3H09A 2XTXA 2NZMA 4OJOA 5AMVA 3EQOA 1GQ8A 1WXRA 1DABA 1O8IA 3SUCA 4XMYA 2B0RA 1QRCA 2BM7A 3JURA 3N6ZA 2X3HA 4XR6A 2YUHA 3SY2A 4AVZA 5JLVC 3EQNA 3PSSA 4V02C 1TYWA 1CLWA 3ZSCA 1QQ1A 4KH3A 2F3LA 1VBLA 3BH7B 4XLCA 1PLUA 1O8HA 4XQFA 2EWEA 3GQ8A 2QZAA 1PXZA 1LLZA 1HF2A 1OFLA 1OFEA 2X85A 1LM1A 1H80A 2O17A 2O0VA 1TYUA 1DBGA 4OZZA 2BM5A 2IQ7A 2XTWA 1BN8A 2PECA 5C1CA 2QY1A 2NTPA 4I84A 4OM9A 4XOTA 2PYHA 1O8KA 1QA2A 4Z03A 1NHCA 4OJLA 3TH0A 1XG2A 1TYVA 2NTBA 2O0WA 2NT6A 1HG8A 1O8GA 1QRBA 2VBMA 3VMVA 4Z05A 3GRHA 2IOUG 4YZ0A 1O8DA 1O8JA 4XLEA 1EZGA 4YZXA 3UW0A 1EA0A 1OFMA 1BHEA 4HWVA 4YCQA 1IDJA 4YEIA 3LYCA 4XKVA 2VBKA 2BM4A 2X6XA 2Z8GA 3B4NA 3LJYA 3WWGA 3KRGA 2V5IA 3GQ7A 4EW9A 3SQVA 3SZEA 1O8EA 2VFOA 2VJJA 1K4ZA 2VFNA 2UVEA 4YZAA 4XN3A 2XTYA 1JTAA 4XONA 2W7ZA 4XOPA 3VSTA 1JRGA 3ZPPA 2VFMA 1KCCA 3DU1X 3LMWA 4W8SA 1IDKA 1CZFA 1O8LA 2QXZA 3VMWA 5C1EA 1WMRA 3PSZA 4U4BA 4OJ6A 2BSPA 3T9GA 2XC1A 2INUA 4OJPA 4URRA 2BM6A 1QJVA 1IB4A 4XLHA 4YDTA 1OGMX 3B8YA 3SYJA 3BH6B 2VFPA 1KCDA 4NK6A 2XT4A 4C2LA 1RWRA 1OOCA 1TSPA 3GQAA 3JX8A 2VFQA 4MXNA 3B90A 1O8MA 2BX6A 5JMCB 2J8IA 3FY3A 3VSUA 2O04A 3VSVA 4MR0A 2VJIA 3RIQA 1RMGA 4XN0A 2O1DA 4XKWA 1AIRA 1K8FA 2NSPA 4YFOA 1IA5A 1QCXA 4Z06A 3GQ9A 4YEJA 3NB2A 4YZQA 1O8FA 4XORA 4YELA 2QX3A 4JRAC 4YC5A 2NSTA 4OZYA 2J8KA 2INVA 4NK8A 4XL9A 1L1IA 3ML3A 2VBEA 2X6YA 4XM3A 4XLAA 1QA1A 4PMHA 2NT9A 3AK5A 1KTWA 3N90A 2UVFA 3NAWA 1RU4A 4U49A 1PE9A 3P4GA 3PETA 4W8RA 1O88A 2QYUA 2XT2A 4OJ5A 1TYXA 2ODLA
chains in the Genus database with same CATH topology
3RIQA 2W7ZA 1HF2A 2VFMA 4OPWA 1TYUA 2BM5A 1QA3A 1KQ5A 1K8FA 2G0YA 4OM9A 1QA2A 3H09A 4OJLA 4OJ6A 3TH0A 1TYVA 4OJOA 1WXRA 4JRAC 2XC1A 1QRBA 1DABA 2IOUG 2B0RA 4OJPA 1QRCA 2BM7A 2BM6A 3N6ZA 3ML3A 2YUHA 5JLVC 4OJ5A 3SYJA 3BH6B 2VFPA 4V02C 1TYWA 1QA1A 1TSPA 3JX8A 3LYCA 3AK5A 3N90A 2VFQA 2BM4A 3LJYA 1CLWA 1QQ1A 4KH3A 2F3LA 2V5IA 3BH7B 3P4GA 3PETA 2BX6A 3SZEA 2J8IA 2VFOA 5JMCB 1K4ZA 2VFNA 1TYXA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2B0R A;  1HF2 A;  2YUH A;  3BH7 B;  2BX6 A;  3BH6 B;  1KQ5 A;  1K8F A;  4V02 C;  1K4Z A; 
#chains in the Genus database with same CATH topology
 5DNS A;  2NTQ A;  2X6W A;  4OPW A;  4XLF A;  1QA3 A;  1DBO A;  1KQ5 A;  1OGO X;  2G0Y A;  2O6W A;  1OFD A;  2PYG A;  4W8Q A;  4W8T A;  1K5C A;  4XNF A;  1EE6 A;  1X0C A;  1LLW A;  3H09 A;  2XTX A;  2NZM A;  4OJO A;  5AMV A;  3EQO A;  1GQ8 A;  1WXR A;  1DAB A;  1O8I A;  3SUC A;  4XMY A;  2B0R A;  1QRC A;  2BM7 A;  3JUR A;  3N6Z A;  2X3H A;  4XR6 A;  2YUH A;  3SY2 A;  4AVZ A;  5JLV C;  3EQN A;  3PSS A;  4V02 C;  1TYW A;  1CLW A;  3ZSC A;  1QQ1 A;  4KH3 A;  2F3L A;  1VBL A;  3BH7 B;  4XLC A;  1PLU A;  1O8H A;  4XQF A;  2EWE A;  3GQ8 A;  2QZA A;  1PXZ A;  1LLZ A;  1HF2 A;  1OFL A;  1OFE A;  2X85 A;  1LM1 A;  1H80 A;  2O17 A;  2O0V A;  1TYU A;  1DBG A;  4OZZ A;  2BM5 A;  2IQ7 A;  2XTW A;  1BN8 A;  2PEC A;  5C1C A;  2QY1 A;  2NTP A;  4I84 A;  4OM9 A;  4XOT A;  2PYH A;  1O8K A;  1QA2 A;  4Z03 A;  1NHC A;  4OJL A;  3TH0 A;  1XG2 A;  1TYV A;  2NTB A;  2O0W A;  2NT6 A;  1HG8 A;  1O8G A;  1QRB A;  2VBM A;  3VMV A;  4Z05 A;  3GRH A;  2IOU G;  4YZ0 A;  1O8D A;  1O8J A;  4XLE A;  1EZG A;  4YZX A;  3UW0 A;  1EA0 A;  1OFM A;  1BHE A;  4HWV A;  4YCQ A;  1IDJ A;  4YEI A;  3LYC A;  4XKV A;  2VBK A;  2BM4 A;  2X6X A;  2Z8G A;  3B4N A;  3LJY A;  3WWG A;  3KRG A;  2V5I A;  3GQ7 A;  4EW9 A;  3SQV A;  3SZE A;  1O8E A;  2VFO A;  2VJJ A;  1K4Z A;  2VFN A;  2UVE A;  4YZA A;  4XN3 A;  2XTY A;  1JTA A;  4XON A;  2W7Z A;  4XOP A;  3VST A;  1JRG A;  3ZPP A;  2VFM A;  1KCC A;  3DU1 X;  3LMW A;  4W8S A;  1IDK A;  1CZF A;  1O8L A;  2QXZ A;  3VMW A;  5C1E A;  1WMR A;  3PSZ A;  4U4B A;  4OJ6 A;  2BSP A;  3T9G A;  2XC1 A;  2INU A;  4OJP A;  4URR A;  2BM6 A;  1QJV A;  1IB4 A;  4XLH A;  4YDT A;  1OGM X;  3B8Y A;  3SYJ A;  3BH6 B;  2VFP A;  1KCD A;  4NK6 A;  2XT4 A;  4C2L A;  1RWR A;  1OOC A;  1TSP A;  3GQA A;  3JX8 A;  2VFQ A;  4MXN A;  3B90 A;  1O8M A;  2BX6 A;  5JMC B;  2J8I A;  3FY3 A;  3VSU A;  2O04 A;  3VSV A;  4MR0 A;  2VJI A;  3RIQ A;  1RMG A;  4XN0 A;  2O1D A;  4XKW A;  1AIR A;  1K8F A;  2NSP A;  4YFO A;  1IA5 A;  1QCX A;  4Z06 A;  3GQ9 A;  4YEJ A;  3NB2 A;  4YZQ A;  1O8F A;  4XOR A;  4YEL A;  2QX3 A;  4JRA C;  4YC5 A;  2NST A;  4OZY A;  2J8K A;  2INV A;  4NK8 A;  4XL9 A;  1L1I A;  3ML3 A;  2VBE A;  2X6Y A;  4XM3 A;  4XLA A;  1QA1 A;  4PMH A;  2NT9 A;  3AK5 A;  1KTW A;  3N90 A;  2UVF A;  3NAW A;  1RU4 A;  4U49 A;  1PE9 A;  3P4G A;  3PET A;  4W8R A;  1O88 A;  2QYU A;  2XT2 A;  4OJ5 A;  1TYX A;  2ODL A; 
#chains in the Genus database with same CATH homology
 3RIQ A;  2W7Z A;  1HF2 A;  2VFM A;  4OPW A;  1TYU A;  2BM5 A;  1QA3 A;  1KQ5 A;  1K8F A;  2G0Y A;  4OM9 A;  1QA2 A;  3H09 A;  4OJL A;  4OJ6 A;  3TH0 A;  1TYV A;  4OJO A;  1WXR A;  4JRA C;  2XC1 A;  1QRB A;  1DAB A;  2IOU G;  2B0R A;  4OJP A;  1QRC A;  2BM7 A;  2BM6 A;  3N6Z A;  3ML3 A;  2YUH A;  5JLV C;  4OJ5 A;  3SYJ A;  3BH6 B;  2VFP A;  4V02 C;  1TYW A;  1QA1 A;  1TSP A;  3JX8 A;  3LYC A;  3AK5 A;  3N90 A;  2VFQ A;  2BM4 A;  3LJY A;  1CLW A;  1QQ1 A;  4KH3 A;  2F3L A;  2V5I A;  3BH7 B;  3P4G A;  3PET A;  2BX6 A;  3SZE A;  2J8I A;  2VFO A;  5JMC B;  1K4Z A;  2VFN A;  1TYX A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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