1OFLA

Crystal structure of chondroitinase b complexed to dermatan sulfate hexasaccharide
Total Genus 185
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
185
sequence length
481
structure length
481
Chain Sequence
EVVASNETLYQVVKEVKPGGLVQIADGTYKDVQLIVSNSGKSGLPITIKALNPGKVFFTGDAKVELRGEHLILEGIWFKDGNRAIQAWKSHGPGLVAIYGSYNRITACVFDCFDEANSAYITTSLTEDGKVPQHCRIDHCSFTDKITFDQVINLNNTARAIKDGSVGGPAMYHRVDHCFFSNPQKPGNAGGGIRIGYYRNDIGRCLVDSNLFMRQDSEAEIITSKSQENVYYGNTYLNCQGTMNFRHGDHQVAINNFYIGNDQRFGYGGMFVWGSRHVIACNYFELSETIKSRGNAALYLNPGAMASEHALAFDMLIANNAFINVNGYAIHFNPLDERRKEYCAANRLKFETPHQLMLKGNLFFKDKPYVYPFFKDDYFIAGKNSWTGNVALGVEKGIPVNISANRSAYKPVKIKDIQPIEGIALDLNALISKGITGKPLSWDEVRPYWLKEMPGTYALTARLSADRAAKFKAVIKRNKEH
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title The Structure of Chondroitin B Lyase Complexed with Glycosaminoglycan Oligosaccharides Unravels a Calcium-Dependent Catalytic Machinery
pubmed doi rcsb
source organism Pedobacter heparinus
molecule tags Lyase
molecule keywords CHONDROITINASE B
total genus 185
structure length 481
sequence length 481
ec nomenclature ec 4.2.2.19: Chondroitin B lyase.
pdb deposition date 2003-04-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF14592 Chondroitinas_B Chondroitinase B
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.160.20.10 Mainly Beta 3 Solenoid Pectate Lyase C-like Single-stranded right-handed beta-helix, Pectin lyase-like 1oflA00
2QX3A 4YZ0A 2UVEA 4OZYA 2VBMA 4YZXA 1X0CA 4XLAA 4C2LA 2O1DA 3B90A 4XLCA 1K5CA 1BN8A 1OGOX 1O8GA 2NTPA 1OOCA 3B4NA 4I84A 1AIRA 4XN3A 3GRHA 4OJLA 2PYGA 2BSPA 2Z8GA 4W8RA 3LMWA 4XR6A 4XL9A 3GQ9A 1WMRA 4XONA 1O8IA 3FY3A 1IA5A 4MXNA 1GQ8A 2O04A 1QCXA 2X6XA 4XLFA 1OGMX 4W8QA 4XKWA 4XKVA 1O8EA 2NSPA 3KRGA 4YELA 3SUCA 1NHCA 3EQNA 1QJVA 4YZAA 2X85A 1KCDA 1PXZA 4Z06A 3VMWA 4YEJA 4Z03A 4XOTA 3B8YA 1HG8A 4AVZA 3GQ8A 4XOPA 2ODLA 3GQ7A 1OFMA 4PMHA 3JURA 4HWVA 4OJPA 4XLHA 1EE6A 2O0WA 3EQOA 2VJJA 4XMYA 1XG2A 4U49A 2NT6A 2X3HA 1DBGA 1BHEA 4OJ6A 3VSTA 4EW9A 2EWEA 1O8HA 2O17A 2PECA 2UVFA 4XM3A 1RWRA 3GQAA 3VSUA 4XORA 2INUA 1VBLA 2QXZA 1O8KA 1O88A 1RMGA 2QY1A 4OZZA 2NT9A 3UW0A 3ZSCA 4OJOA 1CZFA 3ZPPA 1O8DA 1DBOA 2VBEA 4MR0A 2VJIA 1O8FA 4OJ5A 4XLEA 5AMVA 1KCCA 1JTAA 3T9GA 4XN0A 4U4BA 1OFLA 1RU4A 1O8JA 4XNFA 2X6WA 1IDKA 5C1EA 1PLUA 2NSTA 2IQ7A 5C1CA 3VSVA 2NZMA 1IB4A 3VMVA 4W8TA 1O8MA 1KTWA 1IDJA 4URRA 4XQFA 4YZQA 2PYHA 2X6YA 1JRGA 4W8SA 1O8LA 2NTBA 4Z05A 3WWGA 2O0VA 2VBKA 4NK8A 2INVA 1PE9A 2NTQA 4NK6A 1H80A
chains in the Genus database with same CATH superfamily
2QX3A 4YZ0A 2UVEA 4OZYA 2VBMA 4YZXA 1X0CA 4XLAA 4C2LA 2O1DA 3LJYA 5JMCB 4V02C 4JRAC 3B90A 3PSSA 4XLCA 4OPWA 1K5CA 1BN8A 1OGOX 1O8GA 2NTPA 1OOCA 3B4NA 4I84A 1AIRA 4XN3A 2QZAA 3GRHA 4KH3A 2PYGA 4OJLA 3PSZA 1OFEA 5DNSA 2BSPA 2Z8GA 4YEIA 1QRCA 4W8RA 3LMWA 4XR6A 4XL9A 1DABA 3GQ9A 1WMRA 1QA3A 4XONA 1O8IA 3FY3A 1IA5A 4MXNA 1QRBA 1GQ8A 2O04A 2BM6A 1TYWA 1QCXA 2J8KA 2X6XA 3P4GA 4YFOA 4XLFA 1L1IA 1OGMX 4W8QA 4XKWA 4XKVA 1O8EA 2NSPA 3KRGA 4YELA 3SUCA 1NHCA 1QA1A 3EQNA 2B0RA 1QJVA 4YZAA 2X85A 1KCDA 1PXZA 4Z06A 4YCQA 2O6WA 3VMWA 1LM1A 4YEJA 2XTWA 1CLWA 3AK5A 2BM5A 4Z03A 3H09A 4XOTA 3B8YA 1HG8A 2BM4A 4AVZA 1KCCA 2XTYA 1LLWA 3GQ8A 4XOPA 3SQVA 2ODLA 3GQ7A 1OFMA 1OFDA 1EA0A 4PMHA 3JURA 1EZGA 4HWVA 4OJPA 5JLVC 1TYVA 4XLHA 1EE6A 2F3LA 3LYCA 2O0WA 1HF2A 2VJJA 3EQOA 1TYXA 4XMYA 1K8FA 1LLZA 1XG2A 2XC1A 4U49A 2XT4A 2NT6A 2X3HA 1BHEA 1DBGA 4OJ6A 3VSTA 4EW9A 2EWEA 1O8HA 2O17A 2PECA 2UVFA 4XM3A 1RWRA 3GQAA 3VSUA 4XORA 4YDTA 3ML3A 2XTXA 4YC5A 2INUA 1VBLA 2QXZA 1TSPA 2VFNA 2VFPA 3NB2A 1O8KA 1O88A 1RMGA 2QY1A 4OZZA 2NT9A 1KQ5A 3BH7B 3N90A 3UW0A 2IOUG 3ZSCA 3NAWA 4OJOA 3JX8A 3RIQA 1CZFA 3SYJA 1O8DA 1DBOA 2VBEA 3ZPPA 4MR0A 3PETA 2VJIA 3SY2A 1O8FA 2YUHA 4OJ5A 1WXRA 3TH0A 4OM9A 4XLEA 2QYUA 3DU1X 5AMVA 1JTAA 2VFMA 3N6ZA 4XN0A 3T9GA 1K4ZA 1OFLA 2W7ZA 4U4BA 1RU4A 1O8JA 4XNFA 2X6WA 1IDKA 2BM7A 1PLUA 2NSTA 2IQ7A 5C1EA 5C1CA 1QA2A 3VSVA 2NZMA 1IB4A 3VMVA 4W8TA 1O8MA 2BX6A 1KTWA 1QQ1A 1IDJA 4URRA 2J8IA 4XQFA 4YZQA 2PYHA 2VFOA 2X6YA 2XT2A 1JRGA 3BH6B 1TYUA 1O8LA 2G0YA 4W8SA 2V5IA 2NTBA 4Z05A 3WWGA 2O0VA 2VBKA 4NK8A 2INVA 1PE9A 2NTQA 4NK6A 3SZEA 1H80A 2VFQA
chains in the Genus database with same CATH topology
2QX3A 4YZ0A 2UVEA 4OZYA 2VBMA 4YZXA 1X0CA 4XLAA 4C2LA 2O1DA 3B90A 4XLCA 1K5CA 1BN8A 1OGOX 1O8GA 2NTPA 1OOCA 3B4NA 4I84A 1AIRA 4XN3A 3GRHA 4OJLA 2PYGA 2BSPA 2Z8GA 4W8RA 3LMWA 4XR6A 4XL9A 3GQ9A 1WMRA 4XONA 1O8IA 3FY3A 1IA5A 4MXNA 1GQ8A 2O04A 1QCXA 2X6XA 4XLFA 1OGMX 4W8QA 4XKWA 4XKVA 1O8EA 2NSPA 3KRGA 4YELA 3SUCA 1NHCA 3EQNA 1QJVA 4YZAA 2X85A 1KCDA 1PXZA 4Z06A 3VMWA 4YEJA 4Z03A 4XOTA 3B8YA 1HG8A 4AVZA 3GQ8A 4XOPA 2ODLA 3GQ7A 1OFMA 4PMHA 3JURA 4HWVA 4OJPA 4XLHA 1EE6A 2O0WA 3EQOA 2VJJA 4XMYA 1XG2A 4U49A 2NT6A 2X3HA 1DBGA 1BHEA 4OJ6A 3VSTA 4EW9A 2EWEA 1O8HA 2O17A 2PECA 2UVFA 4XM3A 1RWRA 3GQAA 3VSUA 4XORA 2INUA 1VBLA 2QXZA 1O8KA 1O88A 1RMGA 2QY1A 4OZZA 2NT9A 3UW0A 3ZSCA 4OJOA 1CZFA 3ZPPA 1O8DA 1DBOA 2VBEA 4MR0A 2VJIA 1O8FA 4OJ5A 4XLEA 5AMVA 1KCCA 1JTAA 3T9GA 4XN0A 4U4BA 1OFLA 1RU4A 1O8JA 4XNFA 2X6WA 1IDKA 5C1EA 1PLUA 2NSTA 2IQ7A 5C1CA 3VSVA 2NZMA 1IB4A 3VMVA 4W8TA 1O8MA 1KTWA 1IDJA 4URRA 4XQFA 4YZQA 2PYHA 2X6YA 1JRGA 4W8SA 1O8LA 2NTBA 4Z05A 3WWGA 2O0VA 2VBKA 4NK8A 2INVA 1PE9A 2NTQA 4NK6A 1H80A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2QX3 A;  4YZ0 A;  2UVE A;  4OZY A;  2VBM A;  4YZX A;  1X0C A;  4XLA A;  4C2L A;  2O1D A;  3B90 A;  4XLC A;  1K5C A;  1BN8 A;  1OGO X;  1O8G A;  2NTP A;  1OOC A;  3B4N A;  4I84 A;  1AIR A;  4XN3 A;  3GRH A;  4OJL A;  2PYG A;  2BSP A;  2Z8G A;  4W8R A;  3LMW A;  4XR6 A;  4XL9 A;  3GQ9 A;  1WMR A;  4XON A;  1O8I A;  3FY3 A;  1IA5 A;  4MXN A;  1GQ8 A;  2O04 A;  1QCX A;  2X6X A;  4XLF A;  1OGM X;  4W8Q A;  4XKW A;  4XKV A;  1O8E A;  2NSP A;  3KRG A;  4YEL A;  3SUC A;  1NHC A;  3EQN A;  1QJV A;  4YZA A;  2X85 A;  1KCD A;  1PXZ A;  4Z06 A;  3VMW A;  4YEJ A;  4Z03 A;  4XOT A;  3B8Y A;  1HG8 A;  4AVZ A;  3GQ8 A;  4XOP A;  2ODL A;  3GQ7 A;  1OFM A;  4PMH A;  3JUR A;  4HWV A;  4OJP A;  4XLH A;  1EE6 A;  2O0W A;  3EQO A;  2VJJ A;  4XMY A;  1XG2 A;  4U49 A;  2NT6 A;  2X3H A;  1DBG A;  1BHE A;  4OJ6 A;  3VST A;  4EW9 A;  2EWE A;  1O8H A;  2O17 A;  2PEC A;  2UVF A;  4XM3 A;  1RWR A;  3GQA A;  3VSU A;  4XOR A;  2INU A;  1VBL A;  2QXZ A;  1O8K A;  1O88 A;  1RMG A;  2QY1 A;  4OZZ A;  2NT9 A;  3UW0 A;  3ZSC A;  4OJO A;  1CZF A;  3ZPP A;  1O8D A;  1DBO A;  2VBE A;  4MR0 A;  2VJI A;  1O8F A;  4OJ5 A;  4XLE A;  5AMV A;  1KCC A;  1JTA A;  3T9G A;  4XN0 A;  4U4B A;  1OFL A;  1RU4 A;  1O8J A;  4XNF A;  2X6W A;  1IDK A;  5C1E A;  1PLU A;  2NST A;  2IQ7 A;  5C1C A;  3VSV A;  2NZM A;  1IB4 A;  3VMV A;  4W8T A;  1O8M A;  1KTW A;  1IDJ A;  4URR A;  4XQF A;  4YZQ A;  2PYH A;  2X6Y A;  1JRG A;  4W8S A;  1O8L A;  2NTB A;  4Z05 A;  3WWG A;  2O0V A;  2VBK A;  4NK8 A;  2INV A;  1PE9 A;  2NTQ A;  4NK6 A;  1H80 A; 
#chains in the Genus database with same CATH topology
 2QX3 A;  4YZ0 A;  2UVE A;  4OZY A;  2VBM A;  4YZX A;  1X0C A;  4XLA A;  4C2L A;  2O1D A;  3LJY A;  5JMC B;  4V02 C;  4JRA C;  3B90 A;  3PSS A;  4XLC A;  4OPW A;  1K5C A;  1BN8 A;  1OGO X;  1O8G A;  2NTP A;  1OOC A;  3B4N A;  4I84 A;  1AIR A;  4XN3 A;  2QZA A;  3GRH A;  4KH3 A;  2PYG A;  4OJL A;  3PSZ A;  1OFE A;  5DNS A;  2BSP A;  2Z8G A;  4YEI A;  1QRC A;  4W8R A;  3LMW A;  4XR6 A;  4XL9 A;  1DAB A;  3GQ9 A;  1WMR A;  1QA3 A;  4XON A;  1O8I A;  3FY3 A;  1IA5 A;  4MXN A;  1QRB A;  1GQ8 A;  2O04 A;  2BM6 A;  1TYW A;  1QCX A;  2J8K A;  2X6X A;  3P4G A;  4YFO A;  4XLF A;  1L1I A;  1OGM X;  4W8Q A;  4XKW A;  4XKV A;  1O8E A;  2NSP A;  3KRG A;  4YEL A;  3SUC A;  1NHC A;  1QA1 A;  3EQN A;  2B0R A;  1QJV A;  4YZA A;  2X85 A;  1KCD A;  1PXZ A;  4Z06 A;  4YCQ A;  2O6W A;  3VMW A;  1LM1 A;  4YEJ A;  2XTW A;  1CLW A;  3AK5 A;  2BM5 A;  4Z03 A;  3H09 A;  4XOT A;  3B8Y A;  1HG8 A;  2BM4 A;  4AVZ A;  1KCC A;  2XTY A;  1LLW A;  3GQ8 A;  4XOP A;  3SQV A;  2ODL A;  3GQ7 A;  1OFM A;  1OFD A;  1EA0 A;  4PMH A;  3JUR A;  1EZG A;  4HWV A;  4OJP A;  5JLV C;  1TYV A;  4XLH A;  1EE6 A;  2F3L A;  3LYC A;  2O0W A;  1HF2 A;  2VJJ A;  3EQO A;  1TYX A;  4XMY A;  1K8F A;  1LLZ A;  1XG2 A;  2XC1 A;  4U49 A;  2XT4 A;  2NT6 A;  2X3H A;  1BHE A;  1DBG A;  4OJ6 A;  3VST A;  4EW9 A;  2EWE A;  1O8H A;  2O17 A;  2PEC A;  2UVF A;  4XM3 A;  1RWR A;  3GQA A;  3VSU A;  4XOR A;  4YDT A;  3ML3 A;  2XTX A;  4YC5 A;  2INU A;  1VBL A;  2QXZ A;  1TSP A;  2VFN A;  2VFP A;  3NB2 A;  1O8K A;  1O88 A;  1RMG A;  2QY1 A;  4OZZ A;  2NT9 A;  1KQ5 A;  3BH7 B;  3N90 A;  3UW0 A;  2IOU G;  3ZSC A;  3NAW A;  4OJO A;  3JX8 A;  3RIQ A;  1CZF A;  3SYJ A;  1O8D A;  1DBO A;  2VBE A;  3ZPP A;  4MR0 A;  3PET A;  2VJI A;  3SY2 A;  1O8F A;  2YUH A;  4OJ5 A;  1WXR A;  3TH0 A;  4OM9 A;  4XLE A;  2QYU A;  3DU1 X;  5AMV A;  1JTA A;  2VFM A;  3N6Z A;  4XN0 A;  3T9G A;  1K4Z A;  1OFL A;  2W7Z A;  4U4B A;  1RU4 A;  1O8J A;  4XNF A;  2X6W A;  1IDK A;  2BM7 A;  1PLU A;  2NST A;  2IQ7 A;  5C1E A;  5C1C A;  1QA2 A;  3VSV A;  2NZM A;  1IB4 A;  3VMV A;  4W8T A;  1O8M A;  2BX6 A;  1KTW A;  1QQ1 A;  1IDJ A;  4URR A;  2J8I A;  4XQF A;  4YZQ A;  2PYH A;  2VFO A;  2X6Y A;  2XT2 A;  1JRG A;  3BH6 B;  1TYU A;  1O8L A;  2G0Y A;  4W8S A;  2V5I A;  2NTB A;  4Z05 A;  3WWG A;  2O0V A;  2VBK A;  4NK8 A;  2INV A;  1PE9 A;  2NTQ A;  4NK6 A;  3SZE A;  1H80 A;  2VFQ A; 
#chains in the Genus database with same CATH homology
 2QX3 A;  4YZ0 A;  2UVE A;  4OZY A;  2VBM A;  4YZX A;  1X0C A;  4XLA A;  4C2L A;  2O1D A;  3B90 A;  4XLC A;  1K5C A;  1BN8 A;  1OGO X;  1O8G A;  2NTP A;  1OOC A;  3B4N A;  4I84 A;  1AIR A;  4XN3 A;  3GRH A;  4OJL A;  2PYG A;  2BSP A;  2Z8G A;  4W8R A;  3LMW A;  4XR6 A;  4XL9 A;  3GQ9 A;  1WMR A;  4XON A;  1O8I A;  3FY3 A;  1IA5 A;  4MXN A;  1GQ8 A;  2O04 A;  1QCX A;  2X6X A;  4XLF A;  1OGM X;  4W8Q A;  4XKW A;  4XKV A;  1O8E A;  2NSP A;  3KRG A;  4YEL A;  3SUC A;  1NHC A;  3EQN A;  1QJV A;  4YZA A;  2X85 A;  1KCD A;  1PXZ A;  4Z06 A;  3VMW A;  4YEJ A;  4Z03 A;  4XOT A;  3B8Y A;  1HG8 A;  4AVZ A;  3GQ8 A;  4XOP A;  2ODL A;  3GQ7 A;  1OFM A;  4PMH A;  3JUR A;  4HWV A;  4OJP A;  4XLH A;  1EE6 A;  2O0W A;  3EQO A;  2VJJ A;  4XMY A;  1XG2 A;  4U49 A;  2NT6 A;  2X3H A;  1DBG A;  1BHE A;  4OJ6 A;  3VST A;  4EW9 A;  2EWE A;  1O8H A;  2O17 A;  2PEC A;  2UVF A;  4XM3 A;  1RWR A;  3GQA A;  3VSU A;  4XOR A;  2INU A;  1VBL A;  2QXZ A;  1O8K A;  1O88 A;  1RMG A;  2QY1 A;  4OZZ A;  2NT9 A;  3UW0 A;  3ZSC A;  4OJO A;  1CZF A;  3ZPP A;  1O8D A;  1DBO A;  2VBE A;  4MR0 A;  2VJI A;  1O8F A;  4OJ5 A;  4XLE A;  5AMV A;  1KCC A;  1JTA A;  3T9G A;  4XN0 A;  4U4B A;  1OFL A;  1RU4 A;  1O8J A;  4XNF A;  2X6W A;  1IDK A;  5C1E A;  1PLU A;  2NST A;  2IQ7 A;  5C1C A;  3VSV A;  2NZM A;  1IB4 A;  3VMV A;  4W8T A;  1O8M A;  1KTW A;  1IDJ A;  4URR A;  4XQF A;  4YZQ A;  2PYH A;  2X6Y A;  1JRG A;  4W8S A;  1O8L A;  2NTB A;  4Z05 A;  3WWG A;  2O0V A;  2VBK A;  4NK8 A;  2INV A;  1PE9 A;  2NTQ A;  4NK6 A;  1H80 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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