4W8QA

Crystal structure of truncated hemolysin a from p. mirabilis at 1.4 angstroms resolution
Total Genus 78
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
78
sequence length
234
structure length
234
Chain Sequence
NGIVPDAGHQGPDVSAVNGGTQVINIVTPNNEGISHNQYQDFNVGKPGAVFNNALEAGQSQLAGHLNANSNLNGQAASLILNEVVSRNPSFLLGQQEVFGIAAEYVLSNPNGITCDGCGFINTSRSSLVVGNPLFENGQLKGYSTLNNTNLLSLGKNGLNTTGLLDLIAPRIDSRGKITAAEISAFTGQNTFSQHFDILSSQKPVSALDSYFFGSMQSGRIRIINTAEGSGVKL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Proteolysis of truncated hemolysin A yields a stable dimerization interface.
pubmed doi rcsb
molecule tags Toxin
source organism Proteus mirabilis
molecule keywords Hemolysin
total genus 78
structure length 234
sequence length 234
ec nomenclature
pdb deposition date 2014-08-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF05860 Haemagg_act haemagglutination activity domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.160.20.10 Mainly Beta 3 Solenoid Pectate Lyase C-like Single-stranded right-handed beta-helix, Pectin lyase-like 4w8qA00
1PXZA 3LMWA 3B4NA 1BN8A 4XKVA 3ZSCA 1O8EA 1O88A 4OJLA 4XKWA 4XN3A 4XM3A 1PLUA 4Z05A 2PECA 2QX3A 4HWVA 4Z03A 1OGMX 4W8SA 2UVEA 4YZQA 2PYHA 4YZ0A 4W8TA 1WMRA 3EQOA 2PYGA 3VMWA 3VSVA 3GQ9A 4XONA 1O8FA 2BSPA 2O04A 4I84A 4OJPA 1DBGA 4XLAA 3WWGA 2NT9A 1DBOA 3EQNA 1O8JA 1O8LA 5AMVA 3UW0A 2NTPA 3B90A 3VSTA 3VSUA 2VBKA 1CZFA 4URRA 1O8MA 3ZPPA 1HG8A 2UVFA 4U4BA 4XLFA 5C1EA 4PMHA 1OFMA 1QCXA 4XQFA 1H80A 1XG2A 4OJ5A 1KCCA 2NSPA 4XLEA 5C1CA 4NK6A 1OOCA 2INVA 4XLHA 2O1DA 1VBLA 2NSTA 3GRHA 4XR6A 4W8QA 1IA5A 2VJIA 2O17A 2QXZA 3FY3A 4XNFA 4XL9A 2NT6A 4XOTA 1O8HA 4OJOA 1KTWA 4C2LA 4U49A 4EW9A 3SUCA 2O0VA 4AVZA 3B8YA 4XOPA 1IDKA 2VJJA 1EE6A 3T9GA 1NHCA 1O8KA 1AIRA 1JTAA 1JRGA 4YZXA 4OZZA 1RMGA 2INUA 2X6WA 4W8RA 1O8DA 1BHEA 4MR0A 4OJ6A 4NK8A 1OGOX 2VBEA 2Z8GA 1KCDA 1K5CA 2ODLA 4XORA 2O0WA 2NTQA 1OFLA 3VMVA 4OZYA 3KRGA 3JURA 1RWRA 2X6YA 1RU4A 4XLCA 3GQ8A 2IQ7A 2QY1A 4XN0A 1IDJA 2X3HA 2X6XA 1X0CA 3GQAA 1QJVA 4YEJA 2VBMA 3GQ7A 4MXNA 4YELA 2EWEA 4YZAA 1O8IA 4XMYA 1IB4A 2NZMA 1O8GA 1PE9A 4Z06A 2X85A 2NTBA 1GQ8A
chains in the Genus database with same CATH superfamily
1PXZA 2VFQA 2XT2A 3LMWA 3SZEA 3B4NA 1BN8A 4XKVA 2W7ZA 2XTWA 2BX6A 1O8EA 3LYCA 1O88A 3ZSCA 2VFMA 4OJLA 4XKWA 4XN3A 4XM3A 1PLUA 4Z05A 2PECA 2QX3A 3NB2A 1EA0A 4HWVA 4Z03A 2B0RA 1OGMX 4W8SA 2UVEA 1KQ5A 4YZQA 2PYHA 4YZ0A 3LJYA 4W8TA 1WMRA 1TYUA 2QYUA 3EQOA 2PYGA 3VMWA 3VSVA 3GQ9A 4XONA 1WXRA 4JRAC 1O8FA 2BSPA 2O04A 3BH6B 4I84A 3SYJA 4OJPA 4YEIA 4YDTA 1DBGA 3PSZA 4YFOA 4XLAA 3WWGA 2NT9A 3BH7B 1QA2A 1DBOA 2VFNA 1K4ZA 2V5IA 3EQNA 1O8JA 1O8LA 5AMVA 3UW0A 2NTPA 3B90A 3VSTA 3VSUA 5JMCB 2VBKA 1CZFA 4URRA 1O8MA 3ZPPA 1HG8A 1TYXA 2UVFA 4U4BA 4XLFA 4PMHA 5C1EA 1OFMA 1QCXA 2J8IA 4XQFA 4OPWA 3SQVA 1H80A 1XG2A 4OJ5A 1KCCA 2NSPA 1LLWA 4XLEA 1QRBA 5C1CA 2QZAA 4NK6A 1OOCA 2BM6A 2INVA 1DABA 4XLHA 2O1DA 1VBLA 2NSTA 3GRHA 4XR6A 4W8QA 1IA5A 2VJIA 5JLVC 1OFDA 2O17A 1TYWA 2QXZA 3FY3A 2VFOA 3AK5A 4XNFA 2VFPA 4XL9A 2NT6A 1LM1A 4XOTA 1O8HA 1TSPA 3JX8A 4OJOA 1KTWA 4C2LA 1QA3A 4U49A 4EW9A 2XTXA 2O0VA 3P4GA 5DNSA 3NAWA 3B8YA 4XOPA 3SUCA 4AVZA 1IDKA 2VJJA 1EE6A 3T9GA 1NHCA 1O8KA 1AIRA 3PSSA 1JTAA 3DU1X 1JRGA 1CLWA 2YUHA 4YZXA 4KH3A 4OZZA 2F3LA 2BM4A 3H09A 3N90A 1RMGA 2INUA 2X6WA 3PETA 2XTYA 4OM9A 1O8DA 1BHEA 4MR0A 4W8RA 4OJ6A 3RIQA 4NK8A 1OGOX 2J8KA 2VBEA 2Z8GA 1KCDA 1K5CA 2ODLA 4XORA 2O0WA 2NTQA 1TYVA 1OFLA 2XT4A 4OZYA 3KRGA 4V02C 3TH0A 3VMVA 3JURA 1RWRA 4YCQA 2X6YA 1RU4A 1OFEA 3SY2A 1EZGA 1QQ1A 3GQ8A 4XLCA 1K8FA 4YC5A 2IQ7A 2QY1A 4XN0A 1IDJA 2X3HA 2X6XA 1QA1A 1X0CA 2XC1A 3GQAA 2BM5A 1QJVA 4YEJA 1L1IA 1HF2A 2VBMA 3N6ZA 3GQ7A 3ML3A 4MXNA 4YELA 2EWEA 4YZAA 2G0YA 1O8IA 1LLZA 4XMYA 1IB4A 1QRCA 1O8GA 2NZMA 2O6WA 1PE9A 4Z06A 2IOUG 2X85A 2NTBA 2BM7A 1GQ8A
chains in the Genus database with same CATH topology
1PXZA 3LMWA 3B4NA 1BN8A 4XKVA 3ZSCA 1O8EA 1O88A 4OJLA 4XKWA 4XN3A 4XM3A 1PLUA 4Z05A 2PECA 2QX3A 4HWVA 4Z03A 1OGMX 4W8SA 2UVEA 4YZQA 2PYHA 4YZ0A 4W8TA 1WMRA 3EQOA 2PYGA 3VMWA 3VSVA 3GQ9A 4XONA 1O8FA 2BSPA 2O04A 4I84A 4OJPA 1DBGA 4XLAA 3WWGA 2NT9A 1DBOA 3EQNA 1O8JA 1O8LA 5AMVA 3UW0A 2NTPA 3B90A 3VSTA 3VSUA 2VBKA 1CZFA 4URRA 1O8MA 3ZPPA 1HG8A 2UVFA 4U4BA 4XLFA 5C1EA 4PMHA 1OFMA 1QCXA 4XQFA 1H80A 1XG2A 4OJ5A 1KCCA 2NSPA 4XLEA 5C1CA 4NK6A 1OOCA 2INVA 4XLHA 2O1DA 1VBLA 2NSTA 3GRHA 4XR6A 4W8QA 1IA5A 2VJIA 2O17A 2QXZA 3FY3A 4XNFA 4XL9A 2NT6A 4XOTA 1O8HA 4OJOA 1KTWA 4C2LA 4U49A 4EW9A 3SUCA 2O0VA 4AVZA 3B8YA 4XOPA 1IDKA 2VJJA 1EE6A 3T9GA 1NHCA 1O8KA 1AIRA 1JTAA 1JRGA 4YZXA 4OZZA 1RMGA 2INUA 2X6WA 4W8RA 1O8DA 1BHEA 4MR0A 4OJ6A 4NK8A 1OGOX 2VBEA 2Z8GA 1KCDA 1K5CA 2ODLA 4XORA 2O0WA 2NTQA 1OFLA 3VMVA 4OZYA 3KRGA 3JURA 1RWRA 2X6YA 1RU4A 4XLCA 3GQ8A 2IQ7A 2QY1A 4XN0A 1IDJA 2X3HA 2X6XA 1X0CA 3GQAA 1QJVA 4YEJA 2VBMA 3GQ7A 4MXNA 4YELA 2EWEA 4YZAA 1O8IA 4XMYA 1IB4A 2NZMA 1O8GA 1PE9A 4Z06A 2X85A 2NTBA 1GQ8A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1PXZ A;  3LMW A;  3B4N A;  1BN8 A;  4XKV A;  3ZSC A;  1O8E A;  1O88 A;  4OJL A;  4XKW A;  4XN3 A;  4XM3 A;  1PLU A;  4Z05 A;  2PEC A;  2QX3 A;  4HWV A;  4Z03 A;  1OGM X;  4W8S A;  2UVE A;  4YZQ A;  2PYH A;  4YZ0 A;  4W8T A;  1WMR A;  3EQO A;  2PYG A;  3VMW A;  3VSV A;  3GQ9 A;  4XON A;  1O8F A;  2BSP A;  2O04 A;  4I84 A;  4OJP A;  1DBG A;  4XLA A;  3WWG A;  2NT9 A;  1DBO A;  3EQN A;  1O8J A;  1O8L A;  5AMV A;  3UW0 A;  2NTP A;  3B90 A;  3VST A;  3VSU A;  2VBK A;  1CZF A;  4URR A;  1O8M A;  3ZPP A;  1HG8 A;  2UVF A;  4U4B A;  4XLF A;  5C1E A;  4PMH A;  1OFM A;  1QCX A;  4XQF A;  1H80 A;  1XG2 A;  4OJ5 A;  1KCC A;  2NSP A;  4XLE A;  5C1C A;  4NK6 A;  1OOC A;  2INV A;  4XLH A;  2O1D A;  1VBL A;  2NST A;  3GRH A;  4XR6 A;  4W8Q A;  1IA5 A;  2VJI A;  2O17 A;  2QXZ A;  3FY3 A;  4XNF A;  4XL9 A;  2NT6 A;  4XOT A;  1O8H A;  4OJO A;  1KTW A;  4C2L A;  4U49 A;  4EW9 A;  3SUC A;  2O0V A;  4AVZ A;  3B8Y A;  4XOP A;  1IDK A;  2VJJ A;  1EE6 A;  3T9G A;  1NHC A;  1O8K A;  1AIR A;  1JTA A;  1JRG A;  4YZX A;  4OZZ A;  1RMG A;  2INU A;  2X6W A;  4W8R A;  1O8D A;  1BHE A;  4MR0 A;  4OJ6 A;  4NK8 A;  1OGO X;  2VBE A;  2Z8G A;  1KCD A;  1K5C A;  2ODL A;  4XOR A;  2O0W A;  2NTQ A;  1OFL A;  3VMV A;  4OZY A;  3KRG A;  3JUR A;  1RWR A;  2X6Y A;  1RU4 A;  4XLC A;  3GQ8 A;  2IQ7 A;  2QY1 A;  4XN0 A;  1IDJ A;  2X3H A;  2X6X A;  1X0C A;  3GQA A;  1QJV A;  4YEJ A;  2VBM A;  3GQ7 A;  4MXN A;  4YEL A;  2EWE A;  4YZA A;  1O8I A;  4XMY A;  1IB4 A;  2NZM A;  1O8G A;  1PE9 A;  4Z06 A;  2X85 A;  2NTB A;  1GQ8 A; 
#chains in the Genus database with same CATH topology
 1PXZ A;  2VFQ A;  2XT2 A;  3LMW A;  3SZE A;  3B4N A;  1BN8 A;  4XKV A;  2W7Z A;  2XTW A;  2BX6 A;  1O8E A;  3LYC A;  1O88 A;  3ZSC A;  2VFM A;  4OJL A;  4XKW A;  4XN3 A;  4XM3 A;  1PLU A;  4Z05 A;  2PEC A;  2QX3 A;  3NB2 A;  1EA0 A;  4HWV A;  4Z03 A;  2B0R A;  1OGM X;  4W8S A;  2UVE A;  1KQ5 A;  4YZQ A;  2PYH A;  4YZ0 A;  3LJY A;  4W8T A;  1WMR A;  1TYU A;  2QYU A;  3EQO A;  2PYG A;  3VMW A;  3VSV A;  3GQ9 A;  4XON A;  1WXR A;  4JRA C;  1O8F A;  2BSP A;  2O04 A;  3BH6 B;  4I84 A;  3SYJ A;  4OJP A;  4YEI A;  4YDT A;  1DBG A;  3PSZ A;  4YFO A;  4XLA A;  3WWG A;  2NT9 A;  3BH7 B;  1QA2 A;  1DBO A;  2VFN A;  1K4Z A;  2V5I A;  3EQN A;  1O8J A;  1O8L A;  5AMV A;  3UW0 A;  2NTP A;  3B90 A;  3VST A;  3VSU A;  5JMC B;  2VBK A;  1CZF A;  4URR A;  1O8M A;  3ZPP A;  1HG8 A;  1TYX A;  2UVF A;  4U4B A;  4XLF A;  4PMH A;  5C1E A;  1OFM A;  1QCX A;  2J8I A;  4XQF A;  4OPW A;  3SQV A;  1H80 A;  1XG2 A;  4OJ5 A;  1KCC A;  2NSP A;  1LLW A;  4XLE A;  1QRB A;  5C1C A;  2QZA A;  4NK6 A;  1OOC A;  2BM6 A;  2INV A;  1DAB A;  4XLH A;  2O1D A;  1VBL A;  2NST A;  3GRH A;  4XR6 A;  4W8Q A;  1IA5 A;  2VJI A;  5JLV C;  1OFD A;  2O17 A;  1TYW A;  2QXZ A;  3FY3 A;  2VFO A;  3AK5 A;  4XNF A;  2VFP A;  4XL9 A;  2NT6 A;  1LM1 A;  4XOT A;  1O8H A;  1TSP A;  3JX8 A;  4OJO A;  1KTW A;  4C2L A;  1QA3 A;  4U49 A;  4EW9 A;  2XTX A;  2O0V A;  3P4G A;  5DNS A;  3NAW A;  3B8Y A;  4XOP A;  3SUC A;  4AVZ A;  1IDK A;  2VJJ A;  1EE6 A;  3T9G A;  1NHC A;  1O8K A;  1AIR A;  3PSS A;  1JTA A;  3DU1 X;  1JRG A;  1CLW A;  2YUH A;  4YZX A;  4KH3 A;  4OZZ A;  2F3L A;  2BM4 A;  3H09 A;  3N90 A;  1RMG A;  2INU A;  2X6W A;  3PET A;  2XTY A;  4OM9 A;  1O8D A;  1BHE A;  4MR0 A;  4W8R A;  4OJ6 A;  3RIQ A;  4NK8 A;  1OGO X;  2J8K A;  2VBE A;  2Z8G A;  1KCD A;  1K5C A;  2ODL A;  4XOR A;  2O0W A;  2NTQ A;  1TYV A;  1OFL A;  2XT4 A;  4OZY A;  3KRG A;  4V02 C;  3TH0 A;  3VMV A;  3JUR A;  1RWR A;  4YCQ A;  2X6Y A;  1RU4 A;  1OFE A;  3SY2 A;  1EZG A;  1QQ1 A;  3GQ8 A;  4XLC A;  1K8F A;  4YC5 A;  2IQ7 A;  2QY1 A;  4XN0 A;  1IDJ A;  2X3H A;  2X6X A;  1QA1 A;  1X0C A;  2XC1 A;  3GQA A;  2BM5 A;  1QJV A;  4YEJ A;  1L1I A;  1HF2 A;  2VBM A;  3N6Z A;  3GQ7 A;  3ML3 A;  4MXN A;  4YEL A;  2EWE A;  4YZA A;  2G0Y A;  1O8I A;  1LLZ A;  4XMY A;  1IB4 A;  1QRC A;  1O8G A;  2NZM A;  2O6W A;  1PE9 A;  4Z06 A;  2IOU G;  2X85 A;  2NTB A;  2BM7 A;  1GQ8 A; 
#chains in the Genus database with same CATH homology
 1PXZ A;  3LMW A;  3B4N A;  1BN8 A;  4XKV A;  3ZSC A;  1O8E A;  1O88 A;  4OJL A;  4XKW A;  4XN3 A;  4XM3 A;  1PLU A;  4Z05 A;  2PEC A;  2QX3 A;  4HWV A;  4Z03 A;  1OGM X;  4W8S A;  2UVE A;  4YZQ A;  2PYH A;  4YZ0 A;  4W8T A;  1WMR A;  3EQO A;  2PYG A;  3VMW A;  3VSV A;  3GQ9 A;  4XON A;  1O8F A;  2BSP A;  2O04 A;  4I84 A;  4OJP A;  1DBG A;  4XLA A;  3WWG A;  2NT9 A;  1DBO A;  3EQN A;  1O8J A;  1O8L A;  5AMV A;  3UW0 A;  2NTP A;  3B90 A;  3VST A;  3VSU A;  2VBK A;  1CZF A;  4URR A;  1O8M A;  3ZPP A;  1HG8 A;  2UVF A;  4U4B A;  4XLF A;  5C1E A;  4PMH A;  1OFM A;  1QCX A;  4XQF A;  1H80 A;  1XG2 A;  4OJ5 A;  1KCC A;  2NSP A;  4XLE A;  5C1C A;  4NK6 A;  1OOC A;  2INV A;  4XLH A;  2O1D A;  1VBL A;  2NST A;  3GRH A;  4XR6 A;  4W8Q A;  1IA5 A;  2VJI A;  2O17 A;  2QXZ A;  3FY3 A;  4XNF A;  4XL9 A;  2NT6 A;  4XOT A;  1O8H A;  4OJO A;  1KTW A;  4C2L A;  4U49 A;  4EW9 A;  3SUC A;  2O0V A;  4AVZ A;  3B8Y A;  4XOP A;  1IDK A;  2VJJ A;  1EE6 A;  3T9G A;  1NHC A;  1O8K A;  1AIR A;  1JTA A;  1JRG A;  4YZX A;  4OZZ A;  1RMG A;  2INU A;  2X6W A;  4W8R A;  1O8D A;  1BHE A;  4MR0 A;  4OJ6 A;  4NK8 A;  1OGO X;  2VBE A;  2Z8G A;  1KCD A;  1K5C A;  2ODL A;  4XOR A;  2O0W A;  2NTQ A;  1OFL A;  3VMV A;  4OZY A;  3KRG A;  3JUR A;  1RWR A;  2X6Y A;  1RU4 A;  4XLC A;  3GQ8 A;  2IQ7 A;  2QY1 A;  4XN0 A;  1IDJ A;  2X3H A;  2X6X A;  1X0C A;  3GQA A;  1QJV A;  4YEJ A;  2VBM A;  3GQ7 A;  4MXN A;  4YEL A;  2EWE A;  4YZA A;  1O8I A;  4XMY A;  1IB4 A;  2NZM A;  1O8G A;  1PE9 A;  4Z06 A;  2X85 A;  2NTB A;  1GQ8 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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