5JLVC

Receptor binding domain of botulinum neurotoxin a in complex with human glycosylated sv2c
Total Genus 38
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
38
sequence length
97
structure length
97
Chain Sequence
EGRVERDKYANFTINFTMENQIHTGMEYDNGRFIGVKFKSVTFKDSVFKSCTFEDVTSVNTYFKNCTFIDTVFDNTDFEPYKFIDSEFKNCSFFHNK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title N-linked glycosylation of SV2 is required for binding and uptake of botulinum neurotoxin A.
pubmed doi rcsb
molecule tags Hydrolase
source organism Clostridium botulinum
molecule keywords Botulinum neurotoxin type A
total genus 38
structure length 97
sequence length 97
chains with identical sequence D
ec nomenclature
pdb deposition date 2016-04-27
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.160.20.100 Mainly Beta 3 Solenoid Pectate Lyase C-like Pectate Lyase C-like 5jlvC00
4JRAC 2BM4A 5JMCB 2F3LA 2BM7A 2BM6A 2J8IA 2W7ZA 2G0YA 3N90A 2BM5A 5JLVC
chains in the Genus database with same CATH superfamily
4HWVA 1KTWA 1O8EA 4W8SA 1IDKA 1QA2A 1WXRA 1TYXA 1O8MA 2VFPA 4YC5A 3T9GA 3LMWA 4OZYA 3LYCA 1LLZA 1IB4A 2IQ7A 3JX8A 1QJVA 4XORA 2B0RA 2PECA 1OGOX 1PLUA 3GQAA 2QZAA 4YEJA 1O8KA 1O88A 2J8IA 2IOUG 3SUCA 2VBEA 4XLEA 2VJJA 2QXZA 1O8LA 1DBOA 4OZZA 4XONA 4YZXA 4YEIA 2XTWA 4Z05A 2NTPA 2UVEA 2F3LA 1O8DA 1CZFA 3B4NA 1AIRA 1TYVA 1QA3A 2X6XA 3PSSA 4YZAA 4XR6A 2VJIA 4XNFA 1HF2A 1PXZA 2NZMA 1OFDA 2X6WA 3GQ8A 1L1IA 2BX6A 3FY3A 1O8JA 3VSTA 5DNSA 1TYUA 4U49A 2NTBA 4OJ6A 1CLWA 2Z8GA 4YDTA 1KCCA 3NAWA 1XG2A 3AK5A 4EW9A 2VBMA 1QRBA 1RU4A 4XL9A 4AVZA 5C1CA 2BSPA 4XQFA 1OOCA 2O6WA 2X85A 1QRCA 3N90A 3BH7B 4OJ5A 4OJPA 2X3HA 2BM4A 4NK6A 4Z06A 1K5CA 1DBGA 4XKVA 1LLWA 4OJOA 3LJYA 3GQ9A 1TYWA 2NTQA 3PETA 1K4ZA 4MR0A 1H80A 4MXNA 4XM3A 1IDJA 2O1DA 4KH3A 1QQ1A 2XT4A 1QCXA 2V5IA 4XOTA 3VMWA 3SZEA 2QYUA 3B8YA 4XLAA 3EQNA 5C1EA 3ZPPA 3DU1X 4YZ0A 3B90A 4OJLA 4XKWA 2UVFA 3ZSCA 2VFMA 2NT9A 2VBKA 4XLHA 2O04A 4PMHA 2BM7A 1KCDA 1EE6A 2INUA 2NT6A 2VFNA 5AMVA 3KRGA 2EWEA 4OM9A 1O8IA 1IA5A 4XMYA 1EA0A 4W8TA 1RMGA 1BN8A 2BM5A 1JRGA 2NSTA 2PYHA 4I84A 3VSUA 1GQ8A 2O0VA 4OPWA 1NHCA 2VFOA 3GQ7A 2QX3A 3JURA 3PSZA 1DABA 3GRHA 2G0YA 4XLFA 3TH0A 5JLVC 2PYGA 1OFMA 1VBLA 1BHEA 1K8FA 1TSPA 1LM1A 2XTYA 2J8KA 4XN0A 1QA1A 3ML3A 1O8HA 1PE9A 3P4GA 4YCQA 4YELA 3VMVA 4XLCA 2XTXA 2W7ZA 4XOPA 2NSPA 2O0WA 3SY2A 3WWGA 3H09A 1O8FA 4W8RA 1OGMX 2QY1A 1X0CA 4U4BA 4W8QA 1RWRA 1WMRA 1OFEA 4YZQA 3VSVA 5JMCB 3SQVA 2VFQA 4C2LA 4V02C 1KQ5A 3RIQA 2ODLA 4XN3A 2YUHA 4Z03A 1JTAA 3N6ZA 2XC1A 1OFLA 4YFOA 4JRAC 1HG8A 3NB2A 2BM6A 2X6YA 3BH6B 1EZGA 4NK8A 3EQOA 3SYJA 2O17A 3UW0A 4URRA 2INVA 2XT2A 1O8GA
chains in the Genus database with same CATH topology
1TYWA 2F3LA 1K8FA 1TSPA 1K4ZA 3PETA 1QA2A 1TYVA 1QA1A 1QA3A 3ML3A 4KH3A 3P4GA 1QQ1A 2V5IA 1WXRA 1HF2A 1TYXA 3SZEA 2W7ZA 2BX6A 2VFPA 4OJLA 3H09A 3LYCA 1TYUA 3JX8A 4OJ6A 1CLWA 2VFMA 2B0RA 5JLVC 5JMCB 2BM7A 3AK5A 2VFNA 1QRBA 2VFQA 4OM9A 4V02C 1KQ5A 3RIQA 3N90A 1QRCA 2YUHA 2BM5A 3BH7B 3N6ZA 2XC1A 4OJ5A 4OJPA 4JRAC 2BM4A 2BM6A 3BH6B 2J8IA 4OPWA 3SYJA 2VFOA 2IOUG 1DABA 4OJOA 2G0YA 3TH0A 3LJYA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4JRA C;  2BM4 A;  5JMC B;  2F3L A;  2BM7 A;  2BM6 A;  2J8I A;  2W7Z A;  2G0Y A;  3N90 A;  2BM5 A;  5JLV C; 
#chains in the Genus database with same CATH topology
 4HWV A;  1KTW A;  1O8E A;  4W8S A;  1IDK A;  1QA2 A;  1WXR A;  1TYX A;  1O8M A;  2VFP A;  4YC5 A;  3T9G A;  3LMW A;  4OZY A;  3LYC A;  1LLZ A;  1IB4 A;  2IQ7 A;  3JX8 A;  1QJV A;  4XOR A;  2B0R A;  2PEC A;  1OGO X;  1PLU A;  3GQA A;  2QZA A;  4YEJ A;  1O8K A;  1O88 A;  2J8I A;  2IOU G;  3SUC A;  2VBE A;  4XLE A;  2VJJ A;  2QXZ A;  1O8L A;  1DBO A;  4OZZ A;  4XON A;  4YZX A;  4YEI A;  2XTW A;  4Z05 A;  2NTP A;  2UVE A;  2F3L A;  1O8D A;  1CZF A;  3B4N A;  1AIR A;  1TYV A;  1QA3 A;  2X6X A;  3PSS A;  4YZA A;  4XR6 A;  2VJI A;  4XNF A;  1HF2 A;  1PXZ A;  2NZM A;  1OFD A;  2X6W A;  3GQ8 A;  1L1I A;  2BX6 A;  3FY3 A;  1O8J A;  3VST A;  5DNS A;  1TYU A;  4U49 A;  2NTB A;  4OJ6 A;  1CLW A;  2Z8G A;  4YDT A;  1KCC A;  3NAW A;  1XG2 A;  3AK5 A;  4EW9 A;  2VBM A;  1QRB A;  1RU4 A;  4XL9 A;  4AVZ A;  5C1C A;  2BSP A;  4XQF A;  1OOC A;  2O6W A;  2X85 A;  1QRC A;  3N90 A;  3BH7 B;  4OJ5 A;  4OJP A;  2X3H A;  2BM4 A;  4NK6 A;  4Z06 A;  1K5C A;  1DBG A;  4XKV A;  1LLW A;  4OJO A;  3LJY A;  3GQ9 A;  1TYW A;  2NTQ A;  3PET A;  1K4Z A;  4MR0 A;  1H80 A;  4MXN A;  4XM3 A;  1IDJ A;  2O1D A;  4KH3 A;  1QQ1 A;  2XT4 A;  1QCX A;  2V5I A;  4XOT A;  3VMW A;  3SZE A;  2QYU A;  3B8Y A;  4XLA A;  3EQN A;  5C1E A;  3ZPP A;  3DU1 X;  4YZ0 A;  3B90 A;  4OJL A;  4XKW A;  2UVF A;  3ZSC A;  2VFM A;  2NT9 A;  2VBK A;  4XLH A;  2O04 A;  4PMH A;  2BM7 A;  1KCD A;  1EE6 A;  2INU A;  2NT6 A;  2VFN A;  5AMV A;  3KRG A;  2EWE A;  4OM9 A;  1O8I A;  1IA5 A;  4XMY A;  1EA0 A;  4W8T A;  1RMG A;  1BN8 A;  2BM5 A;  1JRG A;  2NST A;  2PYH A;  4I84 A;  3VSU A;  1GQ8 A;  2O0V A;  4OPW A;  1NHC A;  2VFO A;  3GQ7 A;  2QX3 A;  3JUR A;  3PSZ A;  1DAB A;  3GRH A;  2G0Y A;  4XLF A;  3TH0 A;  5JLV C;  2PYG A;  1OFM A;  1VBL A;  1BHE A;  1K8F A;  1TSP A;  1LM1 A;  2XTY A;  2J8K A;  4XN0 A;  1QA1 A;  3ML3 A;  1O8H A;  1PE9 A;  3P4G A;  4YCQ A;  4YEL A;  3VMV A;  4XLC A;  2XTX A;  2W7Z A;  4XOP A;  2NSP A;  2O0W A;  3SY2 A;  3WWG A;  3H09 A;  1O8F A;  4W8R A;  1OGM X;  2QY1 A;  1X0C A;  4U4B A;  4W8Q A;  1RWR A;  1WMR A;  1OFE A;  4YZQ A;  3VSV A;  5JMC B;  3SQV A;  2VFQ A;  4C2L A;  4V02 C;  1KQ5 A;  3RIQ A;  2ODL A;  4XN3 A;  2YUH A;  4Z03 A;  1JTA A;  3N6Z A;  2XC1 A;  1OFL A;  4YFO A;  4JRA C;  1HG8 A;  3NB2 A;  2BM6 A;  2X6Y A;  3BH6 B;  1EZG A;  4NK8 A;  3EQO A;  3SYJ A;  2O17 A;  3UW0 A;  4URR A;  2INV A;  2XT2 A;  1O8G A; 
#chains in the Genus database with same CATH homology
 1TYW A;  2F3L A;  1K8F A;  1TSP A;  1K4Z A;  3PET A;  1QA2 A;  1TYV A;  1QA1 A;  1QA3 A;  3ML3 A;  4KH3 A;  3P4G A;  1QQ1 A;  2V5I A;  1WXR A;  1HF2 A;  1TYX A;  3SZE A;  2W7Z A;  2BX6 A;  2VFP A;  4OJL A;  3H09 A;  3LYC A;  1TYU A;  3JX8 A;  4OJ6 A;  1CLW A;  2VFM A;  2B0R A;  5JLV C;  5JMC B;  2BM7 A;  3AK5 A;  2VFN A;  1QRB A;  2VFQ A;  4OM9 A;  4V02 C;  1KQ5 A;  3RIQ A;  3N90 A;  1QRC A;  2YUH A;  2BM5 A;  3BH7 B;  3N6Z A;  2XC1 A;  4OJ5 A;  4OJP A;  4JRA C;  2BM4 A;  2BM6 A;  3BH6 B;  2J8I A;  4OPW A;  3SYJ A;  2VFO A;  2IOU G;  1DAB A;  4OJO A;  2G0Y A;  3TH0 A;  3LJY A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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