5JLVC

Receptor binding domain of botulinum neurotoxin a in complex with human glycosylated sv2c
Total Genus 38
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
38
sequence length
97
structure length
97
Chain Sequence
EGRVERDKYANFTINFTMENQIHTGMEYDNGRFIGVKFKSVTFKDSVFKSCTFEDVTSVNTYFKNCTFIDTVFDNTDFEPYKFIDSEFKNCSFFHNK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title N-linked glycosylation of SV2 is required for binding and uptake of botulinum neurotoxin A.
pubmed doi rcsb
molecule tags Hydrolase
source organism Clostridium botulinum
molecule keywords Botulinum neurotoxin type A
total genus 38
structure length 97
sequence length 97
chains with identical sequence D
ec nomenclature
pdb deposition date 2016-04-27
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.160.20.100 Mainly Beta 3 Solenoid Pectate Lyase C-like Pectate Lyase C-like 5jlvC00
2BM5A 2J8IA 2BM7A 2BM4A 4JRAC 5JMCB 2G0YA 5JLVC 2BM6A 3N90A 2W7ZA 2F3LA
chains in the Genus database with same CATH superfamily
4EW9A 1EZGA 1O8MA 3UW0A 1O8GA 2BM7A 3GQ7A 3SZEA 1KQ5A 3RIQA 1DBGA 4XN0A 2O0WA 2BM6A 1QRBA 2XTYA 3NAWA 3VMVA 1NHCA 4XQFA 2BSPA 4HWVA 1X0CA 2Z8GA 3PSSA 3ZPPA 2VBKA 2QY1A 1IB4A 3N90A 2PECA 3VSVA 1O8EA 4PMHA 3BH7B 4YEJA 4YC5A 2EWEA 1KCCA 1BHEA 4MR0A 1BN8A 1IDKA 1OGMX 1L1IA 3P4GA 4U49A 4XNFA 4YZXA 1OGOX 2PYHA 3H09A 4YELA 5C1EA 4XM3A 4XR6A 2PYGA 4KH3A 4AVZA 4W8RA 4C2LA 2NSPA 2X6WA 3KRGA 1AIRA 2J8IA 3JURA 1O8JA 4MXNA 1CZFA 3ZSCA 1O8LA 2INUA 2XC1A 4JRAC 5DNSA 2VFQA 1O8FA 1QJVA 1VBLA 3EQOA 1TYWA 3SUCA 2INVA 1O8IA 2BM5A 2UVFA 1IA5A 3GQ8A 1K4ZA 2O1DA 1IDJA 1PLUA 2VFPA 2NSTA 2VFMA 2XT2A 3ML3A 3VSUA 4I84A 3AK5A 1OFLA 4OZYA 4XMYA 4XLFA 1KTWA 1HG8A 4V02C 2VFNA 4YZAA 2X6XA 2QXZA 3GRHA 4OJ5A 4W8TA 1O8DA 3B90A 2F3LA 1DBOA 2VFOA 1KCDA 2X85A 5AMVA 3VMWA 3PETA 5JLVC 1WMRA 1HF2A 4YDTA 3DU1X 1O8HA 2IOUG 3SY2A 1RWRA 2B0RA 3LMWA 1JRGA 1QQ1A 4XOTA 4XLCA 3BH6B 2IQ7A 4OZZA 4Z05A 1QA1A 5JMCB 1TYVA 1CLWA 1LM1A 2XTWA 2UVEA 3VSTA 4W8SA 4YEIA 2O17A 2NTBA 2VBMA 2X3HA 3LYCA 1RMGA 2O0VA 2W7ZA 1O88A 1PE9A 2YUHA 4XKVA 1K5CA 1WXRA 1QA2A 2VBEA 2XT4A 2ODLA 4URRA 4YZQA 3NB2A 3GQAA 4U4BA 1XG2A 2VJJA 3TH0A 3EQNA 4XORA 3WWGA 5C1CA 4XN3A 4Z06A 1O8KA 3SYJA 3B8YA 2NZMA 3LJYA 4XOPA 4XONA 2VJIA 2NT9A 4OJLA 4OJ6A 4XLAA 1TSPA 2NTPA 4XKWA 2J8KA 2BX6A 2QYUA 2XTXA 1PXZA 3GQ9A 4W8QA 3SQVA 4YZ0A 4OJPA 3N6ZA 1H80A 4Z03A 1GQ8A 2QZAA 4NK8A 1LLWA 1OFDA 3B4NA 4OJOA 4OM9A 1JTAA 1RU4A 2O04A 2NTQA 2BM4A 2O6WA 3JX8A 3PSZA 1EA0A 1QRCA 1EE6A 1LLZA 1TYUA 2X6YA 2G0YA 4NK6A 1DABA 1QA3A 4YCQA 4XLEA 1OFEA 2QX3A 3FY3A 1TYXA 2V5IA 1K8FA 4OPWA 4XL9A 4YFOA 1OFMA 1QCXA 4XLHA 2NT6A 3T9GA 1OOCA
chains in the Genus database with same CATH topology
2B0RA 2J8IA 3SYJA 2BM7A 2XC1A 3LJYA 4JRAC 3SZEA 2VFQA 1KQ5A 1QQ1A 3RIQA 2BM6A 1QRBA 1TYWA 4OJLA 4OJ6A 1TSPA 2BM5A 3BH6B 2BX6A 1QA1A 4OJPA 1K4ZA 3N6ZA 5JMCB 1TYVA 4OJOA 4OM9A 1CLWA 2VFPA 3N90A 2VFMA 3ML3A 3AK5A 2BM4A 3JX8A 1QRCA 1TYUA 2VFNA 4V02C 3P4GA 3LYCA 2G0YA 4OJ5A 1DABA 2W7ZA 1QA3A 2F3LA 2YUHA 1WXRA 2VFOA 1QA2A 3H09A 4OPWA 1TYXA 2V5IA 1K8FA 3PETA 4KH3A 3TH0A 5JLVC 3BH7B 1HF2A 2IOUG
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2BM5 A;  2J8I A;  2BM7 A;  2BM4 A;  4JRA C;  5JMC B;  2G0Y A;  5JLV C;  2BM6 A;  3N90 A;  2W7Z A;  2F3L A; 
#chains in the Genus database with same CATH topology
 4EW9 A;  1EZG A;  1O8M A;  3UW0 A;  1O8G A;  2BM7 A;  3GQ7 A;  3SZE A;  1KQ5 A;  3RIQ A;  1DBG A;  4XN0 A;  2O0W A;  2BM6 A;  1QRB A;  2XTY A;  3NAW A;  3VMV A;  1NHC A;  4XQF A;  2BSP A;  4HWV A;  1X0C A;  2Z8G A;  3PSS A;  3ZPP A;  2VBK A;  2QY1 A;  1IB4 A;  3N90 A;  2PEC A;  3VSV A;  1O8E A;  4PMH A;  3BH7 B;  4YEJ A;  4YC5 A;  2EWE A;  1KCC A;  1BHE A;  4MR0 A;  1BN8 A;  1IDK A;  1OGM X;  1L1I A;  3P4G A;  4U49 A;  4XNF A;  4YZX A;  1OGO X;  2PYH A;  3H09 A;  4YEL A;  5C1E A;  4XM3 A;  4XR6 A;  2PYG A;  4KH3 A;  4AVZ A;  4W8R A;  4C2L A;  2NSP A;  2X6W A;  3KRG A;  1AIR A;  2J8I A;  3JUR A;  1O8J A;  4MXN A;  1CZF A;  3ZSC A;  1O8L A;  2INU A;  2XC1 A;  4JRA C;  5DNS A;  2VFQ A;  1O8F A;  1QJV A;  1VBL A;  3EQO A;  1TYW A;  3SUC A;  2INV A;  1O8I A;  2BM5 A;  2UVF A;  1IA5 A;  3GQ8 A;  1K4Z A;  2O1D A;  1IDJ A;  1PLU A;  2VFP A;  2NST A;  2VFM A;  2XT2 A;  3ML3 A;  3VSU A;  4I84 A;  3AK5 A;  1OFL A;  4OZY A;  4XMY A;  4XLF A;  1KTW A;  1HG8 A;  4V02 C;  2VFN A;  4YZA A;  2X6X A;  2QXZ A;  3GRH A;  4OJ5 A;  4W8T A;  1O8D A;  3B90 A;  2F3L A;  1DBO A;  2VFO A;  1KCD A;  2X85 A;  5AMV A;  3VMW A;  3PET A;  5JLV C;  1WMR A;  1HF2 A;  4YDT A;  3DU1 X;  1O8H A;  2IOU G;  3SY2 A;  1RWR A;  2B0R A;  3LMW A;  1JRG A;  1QQ1 A;  4XOT A;  4XLC A;  3BH6 B;  2IQ7 A;  4OZZ A;  4Z05 A;  1QA1 A;  5JMC B;  1TYV A;  1CLW A;  1LM1 A;  2XTW A;  2UVE A;  3VST A;  4W8S A;  4YEI A;  2O17 A;  2NTB A;  2VBM A;  2X3H A;  3LYC A;  1RMG A;  2O0V A;  2W7Z A;  1O88 A;  1PE9 A;  2YUH A;  4XKV A;  1K5C A;  1WXR A;  1QA2 A;  2VBE A;  2XT4 A;  2ODL A;  4URR A;  4YZQ A;  3NB2 A;  3GQA A;  4U4B A;  1XG2 A;  2VJJ A;  3TH0 A;  3EQN A;  4XOR A;  3WWG A;  5C1C A;  4XN3 A;  4Z06 A;  1O8K A;  3SYJ A;  3B8Y A;  2NZM A;  3LJY A;  4XOP A;  4XON A;  2VJI A;  2NT9 A;  4OJL A;  4OJ6 A;  4XLA A;  1TSP A;  2NTP A;  4XKW A;  2J8K A;  2BX6 A;  2QYU A;  2XTX A;  1PXZ A;  3GQ9 A;  4W8Q A;  3SQV A;  4YZ0 A;  4OJP A;  3N6Z A;  1H80 A;  4Z03 A;  1GQ8 A;  2QZA A;  4NK8 A;  1LLW A;  1OFD A;  3B4N A;  4OJO A;  4OM9 A;  1JTA A;  1RU4 A;  2O04 A;  2NTQ A;  2BM4 A;  2O6W A;  3JX8 A;  3PSZ A;  1EA0 A;  1QRC A;  1EE6 A;  1LLZ A;  1TYU A;  2X6Y A;  2G0Y A;  4NK6 A;  1DAB A;  1QA3 A;  4YCQ A;  4XLE A;  1OFE A;  2QX3 A;  3FY3 A;  1TYX A;  2V5I A;  1K8F A;  4OPW A;  4XL9 A;  4YFO A;  1OFM A;  1QCX A;  4XLH A;  2NT6 A;  3T9G A;  1OOC A; 
#chains in the Genus database with same CATH homology
 2B0R A;  2J8I A;  3SYJ A;  2BM7 A;  2XC1 A;  3LJY A;  4JRA C;  3SZE A;  2VFQ A;  1KQ5 A;  1QQ1 A;  3RIQ A;  2BM6 A;  1QRB A;  1TYW A;  4OJL A;  4OJ6 A;  1TSP A;  2BM5 A;  3BH6 B;  2BX6 A;  1QA1 A;  4OJP A;  1K4Z A;  3N6Z A;  5JMC B;  1TYV A;  4OJO A;  4OM9 A;  1CLW A;  2VFP A;  3N90 A;  2VFM A;  3ML3 A;  3AK5 A;  2BM4 A;  3JX8 A;  1QRC A;  1TYU A;  2VFN A;  4V02 C;  3P4G A;  3LYC A;  2G0Y A;  4OJ5 A;  1DAB A;  2W7Z A;  1QA3 A;  2F3L A;  2YUH A;  1WXR A;  2VFO A;  1QA2 A;  3H09 A;  4OPW A;  1TYX A;  2V5I A;  1K8F A;  3PET A;  4KH3 A;  3TH0 A;  5JLV C;  3BH7 B;  1HF2 A;  2IOU G; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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