5JMCB

Receptor binding domain of botulinum neurotoxin a in complex with rat sv2c
Total Genus 36
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
36
sequence length
91
structure length
91
Chain Sequence
DKYANFSINFTMENQVHTGMEYDNGRFLGVKFKSVTFKDSVFKSCTFDDVTSVNTYFKNCTFIDTLFENTDFEPYKFIDSEFQNCSFLHNK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title N-linked glycosylation of SV2 is required for binding and uptake of botulinum neurotoxin A.
pubmed doi rcsb
molecule tags Hydrolase
source organism Clostridium botulinum
molecule keywords Botulinum neurotoxin type A
total genus 36
structure length 91
sequence length 91
chains with identical sequence D, F, H
ec nomenclature
pdb deposition date 2016-04-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF13599 Pentapeptide_4 Pentapeptide repeats (9 copies)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.160.20.100 Mainly Beta 3 Solenoid Pectate Lyase C-like Pectate Lyase C-like 5jmcB00
3N90A 2J8IA 5JLVC 2F3LA 2BM5A 2W7ZA 5JMCB 2BM6A 4JRAC 2BM4A 2G0YA 2BM7A
chains in the Genus database with same CATH superfamily
4YZQA 2F3LA 4XONA 4XN0A 3VSVA 2PYGA 2XC1A 1WMRA 2O0WA 2X6WA 3B4NA 2NSTA 3LYCA 2QYUA 1OGMX 4XQFA 4PMHA 1OGOX 1KCCA 1QA2A 1O8HA 4W8TA 2O17A 1DABA 2UVFA 1TSPA 2NT9A 4YFOA 4XLCA 1O8GA 3ML3A 5DNSA 3ZPPA 1RMGA 2W7ZA 1CLWA 1QQ1A 3GQAA 3UW0A 1IA5A 3VSTA 2BM4A 2XT2A 4YDTA 4OZYA 1O8IA 1JRGA 3AK5A 1LM1A 2NT6A 2NTBA 3VMVA 4YELA 1DBGA 2BM5A 2IOUG 1QCXA 1K4ZA 2X6YA 2X85A 1O8MA 4MR0A 3SYJA 2BSPA 2VBMA 1QA3A 3NB2A 4YEIA 2QY1A 1TYUA 2QZAA 2X6XA 3B8YA 4I84A 4OJ6A 4XORA 3GRHA 1CZFA 3N6ZA 3DU1X 3ZSCA 1QJVA 1K8FA 2VFMA 2XTYA 4XN3A 4Z05A 4W8RA 2QXZA 5AMVA 2J8IA 1O8LA 3FY3A 1KTWA 2VJIA 4NK8A 4Z03A 2INUA 2PECA 4C2LA 2BM6A 4MXNA 4YC5A 2NZMA 3GQ9A 1O8JA 4OPWA 1WXRA 3SZEA 1HF2A 3P4GA 1TYXA 2VFNA 3BH6B 1BHEA 2O6WA 4XLFA 1VBLA 1NHCA 3EQNA 1EA0A 2X3HA 3GQ8A 1O8KA 2O0VA 1XG2A 2BX6A 4URRA 1OFLA 3SY2A 3TH0A 4HWVA 4OM9A 1KQ5A 4Z06A 4YZ0A 4XLEA 3JURA 4OJPA 5JMCB 4U4BA 4XOTA 2VJJA 3BH7B 1IDJA 3LMWA 4W8QA 4OJ5A 3VMWA 4AVZA 1EE6A 1KCDA 1JTAA 2VFQA 1TYVA 1RWRA 1TYWA 4XLAA 2NSPA 1OFEA 1EZGA 2ODLA 1OOCA 1QRCA 1LLWA 3PSSA 1RU4A 4XL9A 3SQVA 3PETA 3NAWA 3N90A 4OJLA 1O8EA 1OFMA 1PXZA 3T9GA 3JX8A 2Z8GA 2NTQA 4U49A 1IB4A 1K5CA 4JRAC 1O88A 4OZZA 2XTXA 3B90A 5C1CA 2VFOA 1QA1A 4YEJA 1HG8A 4XKVA 2VFPA 1OFDA 4XM3A 4OJOA 2EWEA 3PSZA 2INVA 4KH3A 1QRBA 3KRGA 2VBEA 2BM7A 2J8KA 4XKWA 4YCQA 1PLUA 4YZAA 1GQ8A 1LLZA 3H09A 3GQ7A 4V02C 4XMYA 2G0YA 1DBOA 4EW9A 2V5IA 5JLVC 1IDKA 2QX3A 2UVEA 4XOPA 3LJYA 3VSUA 3WWGA 2PYHA 5C1EA 2XT4A 4XLHA 1H80A 4W8SA 2XTWA 3EQOA 1L1IA 3RIQA 4XNFA 2O04A 4NK6A 2NTPA 2YUHA 1BN8A 1AIRA 2B0RA 4YZXA 3SUCA 1O8FA 1O8DA 2VBKA 2IQ7A 1X0CA 2O1DA 4XR6A 1PE9A
chains in the Genus database with same CATH topology
4OJ6A 2VFQA 2F3LA 1TYVA 3H09A 3N6ZA 1TYWA 4V02C 2XC1A 2G0YA 1K8FA 2VFMA 2V5IA 5JLVC 2J8IA 3LYCA 1QRCA 3LJYA 2BM6A 1QA2A 1DABA 3PETA 1TSPA 4OPWA 1WXRA 3N90A 4OJLA 3SZEA 1HF2A 3P4GA 3ML3A 1TYXA 2VFNA 3BH6B 2W7ZA 3JX8A 1CLWA 1QQ1A 3RIQA 4JRAC 2BM4A 2BX6A 3AK5A 3TH0A 2VFOA 4OM9A 1KQ5A 2YUHA 1QA1A 2B0RA 2VFPA 2BM5A 2IOUG 4OJPA 1K4ZA 4OJOA 3SYJA 5JMCB 3BH7B 1QA3A 4OJ5A 4KH3A 1QRBA 2BM7A 1TYUA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3N90 A;  2J8I A;  5JLV C;  2F3L A;  2BM5 A;  2W7Z A;  5JMC B;  2BM6 A;  4JRA C;  2BM4 A;  2G0Y A;  2BM7 A; 
#chains in the Genus database with same CATH topology
 4YZQ A;  2F3L A;  4XON A;  4XN0 A;  3VSV A;  2PYG A;  2XC1 A;  1WMR A;  2O0W A;  2X6W A;  3B4N A;  2NST A;  3LYC A;  2QYU A;  1OGM X;  4XQF A;  4PMH A;  1OGO X;  1KCC A;  1QA2 A;  1O8H A;  4W8T A;  2O17 A;  1DAB A;  2UVF A;  1TSP A;  2NT9 A;  4YFO A;  4XLC A;  1O8G A;  3ML3 A;  5DNS A;  3ZPP A;  1RMG A;  2W7Z A;  1CLW A;  1QQ1 A;  3GQA A;  3UW0 A;  1IA5 A;  3VST A;  2BM4 A;  2XT2 A;  4YDT A;  4OZY A;  1O8I A;  1JRG A;  3AK5 A;  1LM1 A;  2NT6 A;  2NTB A;  3VMV A;  4YEL A;  1DBG A;  2BM5 A;  2IOU G;  1QCX A;  1K4Z A;  2X6Y A;  2X85 A;  1O8M A;  4MR0 A;  3SYJ A;  2BSP A;  2VBM A;  1QA3 A;  3NB2 A;  4YEI A;  2QY1 A;  1TYU A;  2QZA A;  2X6X A;  3B8Y A;  4I84 A;  4OJ6 A;  4XOR A;  3GRH A;  1CZF A;  3N6Z A;  3DU1 X;  3ZSC A;  1QJV A;  1K8F A;  2VFM A;  2XTY A;  4XN3 A;  4Z05 A;  4W8R A;  2QXZ A;  5AMV A;  2J8I A;  1O8L A;  3FY3 A;  1KTW A;  2VJI A;  4NK8 A;  4Z03 A;  2INU A;  2PEC A;  4C2L A;  2BM6 A;  4MXN A;  4YC5 A;  2NZM A;  3GQ9 A;  1O8J A;  4OPW A;  1WXR A;  3SZE A;  1HF2 A;  3P4G A;  1TYX A;  2VFN A;  3BH6 B;  1BHE A;  2O6W A;  4XLF A;  1VBL A;  1NHC A;  3EQN A;  1EA0 A;  2X3H A;  3GQ8 A;  1O8K A;  2O0V A;  1XG2 A;  2BX6 A;  4URR A;  1OFL A;  3SY2 A;  3TH0 A;  4HWV A;  4OM9 A;  1KQ5 A;  4Z06 A;  4YZ0 A;  4XLE A;  3JUR A;  4OJP A;  5JMC B;  4U4B A;  4XOT A;  2VJJ A;  3BH7 B;  1IDJ A;  3LMW A;  4W8Q A;  4OJ5 A;  3VMW A;  4AVZ A;  1EE6 A;  1KCD A;  1JTA A;  2VFQ A;  1TYV A;  1RWR A;  1TYW A;  4XLA A;  2NSP A;  1OFE A;  1EZG A;  2ODL A;  1OOC A;  1QRC A;  1LLW A;  3PSS A;  1RU4 A;  4XL9 A;  3SQV A;  3PET A;  3NAW A;  3N90 A;  4OJL A;  1O8E A;  1OFM A;  1PXZ A;  3T9G A;  3JX8 A;  2Z8G A;  2NTQ A;  4U49 A;  1IB4 A;  1K5C A;  4JRA C;  1O88 A;  4OZZ A;  2XTX A;  3B90 A;  5C1C A;  2VFO A;  1QA1 A;  4YEJ A;  1HG8 A;  4XKV A;  2VFP A;  1OFD A;  4XM3 A;  4OJO A;  2EWE A;  3PSZ A;  2INV A;  4KH3 A;  1QRB A;  3KRG A;  2VBE A;  2BM7 A;  2J8K A;  4XKW A;  4YCQ A;  1PLU A;  4YZA A;  1GQ8 A;  1LLZ A;  3H09 A;  3GQ7 A;  4V02 C;  4XMY A;  2G0Y A;  1DBO A;  4EW9 A;  2V5I A;  5JLV C;  1IDK A;  2QX3 A;  2UVE A;  4XOP A;  3LJY A;  3VSU A;  3WWG A;  2PYH A;  5C1E A;  2XT4 A;  4XLH A;  1H80 A;  4W8S A;  2XTW A;  3EQO A;  1L1I A;  3RIQ A;  4XNF A;  2O04 A;  4NK6 A;  2NTP A;  2YUH A;  1BN8 A;  1AIR A;  2B0R A;  4YZX A;  3SUC A;  1O8F A;  1O8D A;  2VBK A;  2IQ7 A;  1X0C A;  2O1D A;  4XR6 A;  1PE9 A; 
#chains in the Genus database with same CATH homology
 4OJ6 A;  2VFQ A;  2F3L A;  1TYV A;  3H09 A;  3N6Z A;  1TYW A;  4V02 C;  2XC1 A;  2G0Y A;  1K8F A;  2VFM A;  2V5I A;  5JLV C;  2J8I A;  3LYC A;  1QRC A;  3LJY A;  2BM6 A;  1QA2 A;  1DAB A;  3PET A;  1TSP A;  4OPW A;  1WXR A;  3N90 A;  4OJL A;  3SZE A;  1HF2 A;  3P4G A;  3ML3 A;  1TYX A;  2VFN A;  3BH6 B;  2W7Z A;  3JX8 A;  1CLW A;  1QQ1 A;  3RIQ A;  4JRA C;  2BM4 A;  2BX6 A;  3AK5 A;  3TH0 A;  2VFO A;  4OM9 A;  1KQ5 A;  2YUH A;  1QA1 A;  2B0R A;  2VFP A;  2BM5 A;  2IOU G;  4OJP A;  1K4Z A;  4OJO A;  3SYJ A;  5JMC B;  3BH7 B;  1QA3 A;  4OJ5 A;  4KH3 A;  1QRB A;  2BM7 A;  1TYU A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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