5AMVA

Structural insights into the loss of catalytic competence in pectate lyase at low ph
Total Genus 159
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
159
sequence length
399
structure length
397
Chain Sequence
ADLGHQTLGSNDGWGAYSTGTTGGSKASSSNVYTVSNRNQLVSALGKETNTTPKIIYIKGTIDMNVDDNLKPLGLNDYKDPEYDLDKYLKAYDPSTWGKKEPSGTQEEARARSKNQKARVMVDIPANTTIVGSGTNAKVVGGNFQIKSDNVIIRNIEFQDAYDYFPQWDPTDGSSGNWNSQYDNITINGGTHIWIDHCTFNDGSRPDSTSPKYYGRKYQHHDGQTDASNGANYITMSYNYYHDHDKSSIFGSSDSKTSDDGKLKITLHHNRYKNIVQRAPRVRFGQVHVYNNYYEGSTSSSSYPFSYAWGIGKSSKIYAQNNVIDVPGLSAAKTISVFSGGTALYDSGTLLNGTQINASAANGLSSSVGWTPSLHGSIDASANVKNVINQAGAGKLN
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural Insights Into the Loss of Catalytic Competence in Pectate Lyase Activity at Low Ph.
pubmed doi rcsb
molecule tags Lyase
source organism Bacillus subtilis
molecule keywords PECTATE LYASE
total genus 159
structure length 397
sequence length 399
ec nomenclature ec 4.2.2.2: Pectate lyase.
pdb deposition date 2015-09-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00544 Pec_lyase_C Pectate lyase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.160.20.10 Mainly Beta 3 Solenoid Pectate Lyase C-like Single-stranded right-handed beta-helix, Pectin lyase-like 5amvA00
4NK8A 4XONA 3VSVA 3VMVA 2NTBA 4PMHA 3VSUA 1CZFA 2QX3A 5AMVA 1BN8A 2QY1A 1O8DA 2Z8GA 4XN3A 3ZPPA 4YZQA 3T9GA 1IB4A 4XNFA 4OJLA 1DBOA 1O8MA 1X0CA 1XG2A 2PYGA 2PYHA 1OFMA 5C1EA 4W8RA 4XLHA 3B4NA 2X6XA 4URRA 2NZMA 4I84A 4XOPA 4HWVA 4XQFA 1QCXA 1O8GA 1KCDA 1O8LA 4OJ6A 2X3HA 3GRHA 4XR6A 2NSTA 1O8HA 1GQ8A 1HG8A 2VBEA 3ZSCA 4XL9A 4YEJA 4YZXA 1OFLA 1O8FA 2NT6A 1DBGA 3GQ8A 2NT9A 4U49A 2X85A 4MXNA 2O0VA 4Z06A 3B90A 1VBLA 1O88A 4NK6A 4YZ0A 4YZAA 5C1CA 4XLEA 1KCCA 3GQ7A 1NHCA 2O0WA 3EQNA 3LMWA 2VJIA 1PE9A 1JRGA 3JURA 3VSTA 4XLAA 1RMGA 4OJ5A 1IDKA 2X6YA 4W8SA 4XN0A 4XORA 1OGOX 2EWEA 2VJJA 1EE6A 1O8IA 4AVZA 4XLCA 4MR0A 1RU4A 3GQ9A 2ODLA 2INVA 4XOTA 1OGMX 4OJOA 2NTPA 2VBKA 4OZZA 1QJVA 2VBMA 3B8YA 4OJPA 2O1DA 1IDJA 3EQOA 2O17A 2X6WA 1PLUA 4Z03A 2NSPA 2UVEA 1O8EA 1JTAA 1O8KA 4XKVA 2UVFA 3SUCA 4W8TA 2PECA 1O8JA 2BSPA 3GQAA 1OOCA 3KRGA 1KTWA 2O04A 2QXZA 1RWRA 4XKWA 4U4BA 2INUA 4Z05A 3UW0A 1PXZA 4OZYA 4YELA 1IA5A 1H80A 3WWGA 4W8QA 3FY3A 4XMYA 1K5CA 1BHEA 1AIRA 2IQ7A 4XM3A 4C2LA 4XLFA 2NTQA 1WMRA 4EW9A 3VMWA
chains in the Genus database with same CATH superfamily
4NK8A 3LJYA 4XONA 3VSVA 2XT2A 4OM9A 1QRCA 1TYWA 2BX6A 3VMVA 2NTBA 4PMHA 4YEIA 4OPWA 1QA2A 3VSUA 1CZFA 1TSPA 2QX3A 5AMVA 1BN8A 2QY1A 1O8DA 2Z8GA 4XN3A 3ZPPA 4YZQA 3DU1X 3T9GA 1IB4A 3PETA 2V5IA 4XNFA 3NAWA 1L1IA 4OJLA 1DBOA 1O8MA 1X0CA 1XG2A 2PYGA 2PYHA 1EZGA 1OFMA 2O6WA 5C1EA 4W8RA 4XLHA 2VFPA 3B4NA 2X6XA 4URRA 4YCQA 2NZMA 2VFOA 4I84A 4XOPA 4HWVA 4XQFA 4YC5A 1QCXA 1O8GA 1LLWA 1KCDA 1O8LA 1QRBA 5DNSA 4OJ6A 2X3HA 3GRHA 4XR6A 2J8KA 2NSTA 1O8HA 1GQ8A 1HG8A 2VBEA 3ZSCA 3AK5A 4XL9A 4YEJA 4YZXA 1QA3A 1OFLA 1O8FA 2NT6A 2VFNA 1DBGA 3GQ8A 2NT9A 1OFEA 1HF2A 2X85A 4U49A 4MXNA 2NTQA 2O0VA 4Z06A 3B90A 1VBLA 1O88A 2W7ZA 4NK6A 2G0YA 2XC1A 4YZAA 4V02C 4XLEA 3GQ7A 4YZ0A 5C1CA 1KCCA 2O0WA 1NHCA 3EQNA 3LMWA 2VJIA 1PE9A 1JRGA 3JURA 3N6ZA 3VSTA 5JMCB 4XLAA 1RMGA 1WXRA 2XTYA 1EA0A 4OJ5A 1IDKA 2X6YA 4W8SA 4XN0A 4XORA 1OGOX 1QQ1A 2EWEA 1TYXA 2VJJA 2IOUG 3NB2A 1EE6A 1O8IA 3PSZA 4AVZA 4XLCA 2BM7A 4MR0A 1RU4A 1DABA 4KH3A 4YDTA 1CLWA 2QZAA 2VFMA 1TYUA 3GQ9A 1TYVA 2INVA 2ODLA 4XOTA 2B0RA 4JRAC 1K8FA 1OGMX 4OJOA 2NTPA 2VBKA 4YFOA 4OZZA 3LYCA 2YUHA 1QJVA 2VBMA 1LLZA 3B8YA 1KQ5A 4OJPA 2O1DA 1IDJA 3EQOA 2O17A 2X6WA 1PLUA 3BH7B 4Z03A 3H09A 2NSPA 2UVEA 1O8EA 3TH0A 2BM4A 2J8IA 3SY2A 2XT4A 1JTAA 3BH6B 3PSSA 3SQVA 1O8KA 4XKVA 2UVFA 1K4ZA 3RIQA 3SUCA 1QA1A 2XTXA 4W8TA 2PECA 1O8JA 2BSPA 3GQAA 3SYJA 1OOCA 3KRGA 1KTWA 3SZEA 2BM6A 2O04A 2QXZA 1RWRA 4XKWA 1OFDA 4U4BA 2INUA 4Z05A 2VFQA 3UW0A 1PXZA 3JX8A 2XTWA 5JLVC 3P4GA 3N90A 4OZYA 4YELA 2BM5A 1IA5A 1H80A 2F3LA 3WWGA 4W8QA 3FY3A 4XMYA 1K5CA 1BHEA 1AIRA 3ML3A 2IQ7A 4XM3A 4C2LA 2QYUA 4XLFA 1LM1A 1WMRA 4EW9A 3VMWA
chains in the Genus database with same CATH topology
4NK8A 4XONA 3VSVA 3VMVA 2NTBA 4PMHA 3VSUA 1CZFA 2QX3A 5AMVA 1BN8A 2QY1A 1O8DA 2Z8GA 4XN3A 3ZPPA 4YZQA 3T9GA 1IB4A 4XNFA 4OJLA 1DBOA 1O8MA 1X0CA 1XG2A 2PYGA 2PYHA 1OFMA 5C1EA 4W8RA 4XLHA 3B4NA 2X6XA 4URRA 2NZMA 4I84A 4XOPA 4HWVA 4XQFA 1QCXA 1O8GA 1KCDA 1O8LA 4OJ6A 2X3HA 3GRHA 4XR6A 2NSTA 1O8HA 1GQ8A 1HG8A 2VBEA 3ZSCA 4XL9A 4YEJA 4YZXA 1OFLA 1O8FA 2NT6A 1DBGA 3GQ8A 2NT9A 4U49A 2X85A 4MXNA 2O0VA 4Z06A 3B90A 1VBLA 1O88A 4NK6A 4YZ0A 4YZAA 5C1CA 4XLEA 1KCCA 3GQ7A 1NHCA 2O0WA 3EQNA 3LMWA 2VJIA 1PE9A 1JRGA 3JURA 3VSTA 4XLAA 1RMGA 4OJ5A 1IDKA 2X6YA 4W8SA 4XN0A 4XORA 1OGOX 2EWEA 2VJJA 1EE6A 1O8IA 4AVZA 4XLCA 4MR0A 1RU4A 3GQ9A 2ODLA 2INVA 4XOTA 1OGMX 4OJOA 2NTPA 2VBKA 4OZZA 1QJVA 2VBMA 3B8YA 4OJPA 2O1DA 1IDJA 3EQOA 2O17A 2X6WA 1PLUA 4Z03A 2NSPA 2UVEA 1O8EA 1JTAA 1O8KA 4XKVA 2UVFA 3SUCA 4W8TA 2PECA 1O8JA 2BSPA 3GQAA 1OOCA 3KRGA 1KTWA 2O04A 2QXZA 1RWRA 4XKWA 4U4BA 2INUA 4Z05A 3UW0A 1PXZA 4OZYA 4YELA 1IA5A 1H80A 3WWGA 4W8QA 3FY3A 4XMYA 1K5CA 1BHEA 1AIRA 2IQ7A 4XM3A 4C2LA 4XLFA 2NTQA 1WMRA 4EW9A 3VMWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4NK8 A;  4XON A;  3VSV A;  3VMV A;  2NTB A;  4PMH A;  3VSU A;  1CZF A;  2QX3 A;  5AMV A;  1BN8 A;  2QY1 A;  1O8D A;  2Z8G A;  4XN3 A;  3ZPP A;  4YZQ A;  3T9G A;  1IB4 A;  4XNF A;  4OJL A;  1DBO A;  1O8M A;  1X0C A;  1XG2 A;  2PYG A;  2PYH A;  1OFM A;  5C1E A;  4W8R A;  4XLH A;  3B4N A;  2X6X A;  4URR A;  2NZM A;  4I84 A;  4XOP A;  4HWV A;  4XQF A;  1QCX A;  1O8G A;  1KCD A;  1O8L A;  4OJ6 A;  2X3H A;  3GRH A;  4XR6 A;  2NST A;  1O8H A;  1GQ8 A;  1HG8 A;  2VBE A;  3ZSC A;  4XL9 A;  4YEJ A;  4YZX A;  1OFL A;  1O8F A;  2NT6 A;  1DBG A;  3GQ8 A;  2NT9 A;  4U49 A;  2X85 A;  4MXN A;  2O0V A;  4Z06 A;  3B90 A;  1VBL A;  1O88 A;  4NK6 A;  4YZ0 A;  4YZA A;  5C1C A;  4XLE A;  1KCC A;  3GQ7 A;  1NHC A;  2O0W A;  3EQN A;  3LMW A;  2VJI A;  1PE9 A;  1JRG A;  3JUR A;  3VST A;  4XLA A;  1RMG A;  4OJ5 A;  1IDK A;  2X6Y A;  4W8S A;  4XN0 A;  4XOR A;  1OGO X;  2EWE A;  2VJJ A;  1EE6 A;  1O8I A;  4AVZ A;  4XLC A;  4MR0 A;  1RU4 A;  3GQ9 A;  2ODL A;  2INV A;  4XOT A;  1OGM X;  4OJO A;  2NTP A;  2VBK A;  4OZZ A;  1QJV A;  2VBM A;  3B8Y A;  4OJP A;  2O1D A;  1IDJ A;  3EQO A;  2O17 A;  2X6W A;  1PLU A;  4Z03 A;  2NSP A;  2UVE A;  1O8E A;  1JTA A;  1O8K A;  4XKV A;  2UVF A;  3SUC A;  4W8T A;  2PEC A;  1O8J A;  2BSP A;  3GQA A;  1OOC A;  3KRG A;  1KTW A;  2O04 A;  2QXZ A;  1RWR A;  4XKW A;  4U4B A;  2INU A;  4Z05 A;  3UW0 A;  1PXZ A;  4OZY A;  4YEL A;  1IA5 A;  1H80 A;  3WWG A;  4W8Q A;  3FY3 A;  4XMY A;  1K5C A;  1BHE A;  1AIR A;  2IQ7 A;  4XM3 A;  4C2L A;  4XLF A;  2NTQ A;  1WMR A;  4EW9 A;  3VMW A; 
#chains in the Genus database with same CATH topology
 4NK8 A;  3LJY A;  4XON A;  3VSV A;  2XT2 A;  4OM9 A;  1QRC A;  1TYW A;  2BX6 A;  3VMV A;  2NTB A;  4PMH A;  4YEI A;  4OPW A;  1QA2 A;  3VSU A;  1CZF A;  1TSP A;  2QX3 A;  5AMV A;  1BN8 A;  2QY1 A;  1O8D A;  2Z8G A;  4XN3 A;  3ZPP A;  4YZQ A;  3DU1 X;  3T9G A;  1IB4 A;  3PET A;  2V5I A;  4XNF A;  3NAW A;  1L1I A;  4OJL A;  1DBO A;  1O8M A;  1X0C A;  1XG2 A;  2PYG A;  2PYH A;  1EZG A;  1OFM A;  2O6W A;  5C1E A;  4W8R A;  4XLH A;  2VFP A;  3B4N A;  2X6X A;  4URR A;  4YCQ A;  2NZM A;  2VFO A;  4I84 A;  4XOP A;  4HWV A;  4XQF A;  4YC5 A;  1QCX A;  1O8G A;  1LLW A;  1KCD A;  1O8L A;  1QRB A;  5DNS A;  4OJ6 A;  2X3H A;  3GRH A;  4XR6 A;  2J8K A;  2NST A;  1O8H A;  1GQ8 A;  1HG8 A;  2VBE A;  3ZSC A;  3AK5 A;  4XL9 A;  4YEJ A;  4YZX A;  1QA3 A;  1OFL A;  1O8F A;  2NT6 A;  2VFN A;  1DBG A;  3GQ8 A;  2NT9 A;  1OFE A;  1HF2 A;  2X85 A;  4U49 A;  4MXN A;  2NTQ A;  2O0V A;  4Z06 A;  3B90 A;  1VBL A;  1O88 A;  2W7Z A;  4NK6 A;  2G0Y A;  2XC1 A;  4YZA A;  4V02 C;  4XLE A;  3GQ7 A;  4YZ0 A;  5C1C A;  1KCC A;  2O0W A;  1NHC A;  3EQN A;  3LMW A;  2VJI A;  1PE9 A;  1JRG A;  3JUR A;  3N6Z A;  3VST A;  5JMC B;  4XLA A;  1RMG A;  1WXR A;  2XTY A;  1EA0 A;  4OJ5 A;  1IDK A;  2X6Y A;  4W8S A;  4XN0 A;  4XOR A;  1OGO X;  1QQ1 A;  2EWE A;  1TYX A;  2VJJ A;  2IOU G;  3NB2 A;  1EE6 A;  1O8I A;  3PSZ A;  4AVZ A;  4XLC A;  2BM7 A;  4MR0 A;  1RU4 A;  1DAB A;  4KH3 A;  4YDT A;  1CLW A;  2QZA A;  2VFM A;  1TYU A;  3GQ9 A;  1TYV A;  2INV A;  2ODL A;  4XOT A;  2B0R A;  4JRA C;  1K8F A;  1OGM X;  4OJO A;  2NTP A;  2VBK A;  4YFO A;  4OZZ A;  3LYC A;  2YUH A;  1QJV A;  2VBM A;  1LLZ A;  3B8Y A;  1KQ5 A;  4OJP A;  2O1D A;  1IDJ A;  3EQO A;  2O17 A;  2X6W A;  1PLU A;  3BH7 B;  4Z03 A;  3H09 A;  2NSP A;  2UVE A;  1O8E A;  3TH0 A;  2BM4 A;  2J8I A;  3SY2 A;  2XT4 A;  1JTA A;  3BH6 B;  3PSS A;  3SQV A;  1O8K A;  4XKV A;  2UVF A;  1K4Z A;  3RIQ A;  3SUC A;  1QA1 A;  2XTX A;  4W8T A;  2PEC A;  1O8J A;  2BSP A;  3GQA A;  3SYJ A;  1OOC A;  3KRG A;  1KTW A;  3SZE A;  2BM6 A;  2O04 A;  2QXZ A;  1RWR A;  4XKW A;  1OFD A;  4U4B A;  2INU A;  4Z05 A;  2VFQ A;  3UW0 A;  1PXZ A;  3JX8 A;  2XTW A;  5JLV C;  3P4G A;  3N90 A;  4OZY A;  4YEL A;  2BM5 A;  1IA5 A;  1H80 A;  2F3L A;  3WWG A;  4W8Q A;  3FY3 A;  4XMY A;  1K5C A;  1BHE A;  1AIR A;  3ML3 A;  2IQ7 A;  4XM3 A;  4C2L A;  2QYU A;  4XLF A;  1LM1 A;  1WMR A;  4EW9 A;  3VMW A; 
#chains in the Genus database with same CATH homology
 4NK8 A;  4XON A;  3VSV A;  3VMV A;  2NTB A;  4PMH A;  3VSU A;  1CZF A;  2QX3 A;  5AMV A;  1BN8 A;  2QY1 A;  1O8D A;  2Z8G A;  4XN3 A;  3ZPP A;  4YZQ A;  3T9G A;  1IB4 A;  4XNF A;  4OJL A;  1DBO A;  1O8M A;  1X0C A;  1XG2 A;  2PYG A;  2PYH A;  1OFM A;  5C1E A;  4W8R A;  4XLH A;  3B4N A;  2X6X A;  4URR A;  2NZM A;  4I84 A;  4XOP A;  4HWV A;  4XQF A;  1QCX A;  1O8G A;  1KCD A;  1O8L A;  4OJ6 A;  2X3H A;  3GRH A;  4XR6 A;  2NST A;  1O8H A;  1GQ8 A;  1HG8 A;  2VBE A;  3ZSC A;  4XL9 A;  4YEJ A;  4YZX A;  1OFL A;  1O8F A;  2NT6 A;  1DBG A;  3GQ8 A;  2NT9 A;  4U49 A;  2X85 A;  4MXN A;  2O0V A;  4Z06 A;  3B90 A;  1VBL A;  1O88 A;  4NK6 A;  4YZ0 A;  4YZA A;  5C1C A;  4XLE A;  1KCC A;  3GQ7 A;  1NHC A;  2O0W A;  3EQN A;  3LMW A;  2VJI A;  1PE9 A;  1JRG A;  3JUR A;  3VST A;  4XLA A;  1RMG A;  4OJ5 A;  1IDK A;  2X6Y A;  4W8S A;  4XN0 A;  4XOR A;  1OGO X;  2EWE A;  2VJJ A;  1EE6 A;  1O8I A;  4AVZ A;  4XLC A;  4MR0 A;  1RU4 A;  3GQ9 A;  2ODL A;  2INV A;  4XOT A;  1OGM X;  4OJO A;  2NTP A;  2VBK A;  4OZZ A;  1QJV A;  2VBM A;  3B8Y A;  4OJP A;  2O1D A;  1IDJ A;  3EQO A;  2O17 A;  2X6W A;  1PLU A;  4Z03 A;  2NSP A;  2UVE A;  1O8E A;  1JTA A;  1O8K A;  4XKV A;  2UVF A;  3SUC A;  4W8T A;  2PEC A;  1O8J A;  2BSP A;  3GQA A;  1OOC A;  3KRG A;  1KTW A;  2O04 A;  2QXZ A;  1RWR A;  4XKW A;  4U4B A;  2INU A;  4Z05 A;  3UW0 A;  1PXZ A;  4OZY A;  4YEL A;  1IA5 A;  1H80 A;  3WWG A;  4W8Q A;  3FY3 A;  4XMY A;  1K5C A;  1BHE A;  1AIR A;  2IQ7 A;  4XM3 A;  4C2L A;  4XLF A;  2NTQ A;  1WMR A;  4EW9 A;  3VMW A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...