5JLVC

Receptor binding domain of botulinum neurotoxin a in complex with human glycosylated sv2c
Total Genus 38
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
38
sequence length
97
structure length
97
Chain Sequence
EGRVERDKYANFTINFTMENQIHTGMEYDNGRFIGVKFKSVTFKDSVFKSCTFEDVTSVNTYFKNCTFIDTVFDNTDFEPYKFIDSEFKNCSFFHNK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title N-linked glycosylation of SV2 is required for binding and uptake of botulinum neurotoxin A.
pubmed doi rcsb
molecule tags Hydrolase
source organism Clostridium botulinum
molecule keywords Botulinum neurotoxin type A
total genus 38
structure length 97
sequence length 97
chains with identical sequence D
ec nomenclature
pdb deposition date 2016-04-27
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.160.20.100 Mainly Beta 3 Solenoid Pectate Lyase C-like Pectate Lyase C-like 5jlvC00
5JMCB 2BM5A 3N90A 4JRAC 2J8IA 5JLVC 2F3LA 2W7ZA 2G0YA 2BM4A 2BM6A 2BM7A
chains in the Genus database with same CATH superfamily
2X6YA 2XT4A 3ML3A 4OJ6A 1QCXA 1TYVA 1DBGA 3KRGA 1IDJA 3GQAA 1IB4A 2PYGA 2PYHA 3H09A 4XLCA 1CZFA 1JTAA 1HF2A 4OJOA 4YFOA 2O6WA 3VSTA 3JX8A 1LM1A 3N6ZA 4Z06A 3TH0A 3WWGA 2QYUA 3ZPPA 4W8RA 1IDKA 2XTXA 1OFMA 1OGMX 2VFPA 4MR0A 4URRA 3RIQA 3LJYA 1KTWA 1O8IA 3LYCA 5JMCB 3GQ9A 2O0WA 2G0YA 2V5IA 4HWVA 1HG8A 2BM6A 1QQ1A 3SUCA 1LLZA 2NSPA 2BX6A 1O88A 2NTBA 3GQ7A 3DU1X 4U4BA 4OM9A 2INVA 5C1CA 1TYWA 1AIRA 2W7ZA 4XN0A 4YELA 4XMYA 1OFDA 2NT9A 4XKVA 1DBOA 1K8FA 4JRAC 4XR6A 2ODLA 2QXZA 5C1EA 2VFQA 4KH3A 4XM3A 1NHCA 2IOUG 1DABA 1EA0A 4MXNA 4YC5A 2QX3A 4XQFA 4XN3A 1EZGA 4YEJA 1X0CA 2O04A 4YZAA 3SZEA 3VMWA 1BHEA 4YZQA 1OGOX 3UW0A 1LLWA 4I84A 2O0VA 4OJPA 4XONA 1RMGA 3EQOA 3LMWA 2NT6A 3PSSA 4AVZA 4EW9A 1QRBA 3SYJA 2VBEA 4XNFA 2QZAA 1TYXA 1VBLA 4NK6A 4OZZA 4PMHA 3VSVA 2J8KA 2O17A 4U49A 4YZXA 1KCCA 1PLUA 1IA5A 1RWRA 4XLFA 1EE6A 1OOCA 3AK5A 1O8MA 2VFOA 2XTYA 2INUA 3T9GA 2X6WA 1K4ZA 4YZ0A 1O8DA 3VSUA 2VFMA 2NSTA 2BSPA 2NTPA 2X85A 3BH7B 2PECA 4W8QA 4XLEA 5DNSA 4Z05A 2F3LA 3SY2A 3NB2A 4YEIA 2UVEA 4NK8A 1XG2A 4XLAA 4OPWA 2BM5A 1O8LA 1O8JA 2IQ7A 2XC1A 3EQNA 2VJIA 1WXRA 4XKWA 1QA1A 1QJVA 1QRCA 2X3HA 2VBMA 3B4NA 4W8SA 4XOTA 3ZSCA 4YDTA 2VBKA 3JURA 4Z03A 1O8FA 1RU4A 1O8HA 2O1DA 2XTWA 4XLHA 1L1IA 1QA2A 2EWEA 3BH6B 1KCDA 1K5CA 2VFNA 1QA3A 4OJLA 2B0RA 1O8EA 3B8YA 1WMRA 3GRHA 2NZMA 1TYUA 1PE9A 2Z8GA 3P4GA 4XOPA 2VJJA 3SQVA 1TSPA 3FY3A 1O8KA 2NTQA 4OJ5A 3GQ8A 2J8IA 2QY1A 4W8TA 3PSZA 2YUHA 3PETA 3VMVA 4OZYA 5AMVA 1OFLA 1JRGA 4XORA 2XT2A 5JLVC 4C2LA 2BM4A 1H80A 1O8GA 4YCQA 1KQ5A 2X6XA 2UVFA 3N90A 3NAWA 1BN8A 1GQ8A 4XL9A 1OFEA 1CLWA 3B90A 2BM7A 1PXZA 4V02C
chains in the Genus database with same CATH topology
4JRAC 3ML3A 4OJ6A 2VFNA 2VFOA 1TYVA 1QA3A 4OJLA 3AK5A 2B0RA 3P4GA 2VFQA 4KH3A 1TYUA 1K4ZA 2IOUG 1DABA 1HF2A 4OJOA 1TSPA 2VFMA 4OJ5A 3BH7B 3JX8A 2J8IA 3SZEA 3N6ZA 3TH0A 2F3LA 2YUHA 3PETA 2VFPA 3RIQA 4OJPA 3LJYA 3LYCA 4OPWA 5JMCB 2BM5A 1QA2A 1QRBA 5JLVC 3SYJA 2G0YA 2V5IA 2BM4A 2XC1A 1WXRA 2BM6A 1QA1A 1QQ1A 1KQ5A 1QRCA 2BX6A 1TYXA 3N90A 4OM9A 1TYWA 2W7ZA 1CLWA 2BM7A 3H09A 1K8FA 4V02C 3BH6B
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5JMC B;  2BM5 A;  3N90 A;  4JRA C;  2J8I A;  5JLV C;  2F3L A;  2W7Z A;  2G0Y A;  2BM4 A;  2BM6 A;  2BM7 A; 
#chains in the Genus database with same CATH topology
 2X6Y A;  2XT4 A;  3ML3 A;  4OJ6 A;  1QCX A;  1TYV A;  1DBG A;  3KRG A;  1IDJ A;  3GQA A;  1IB4 A;  2PYG A;  2PYH A;  3H09 A;  4XLC A;  1CZF A;  1JTA A;  1HF2 A;  4OJO A;  4YFO A;  2O6W A;  3VST A;  3JX8 A;  1LM1 A;  3N6Z A;  4Z06 A;  3TH0 A;  3WWG A;  2QYU A;  3ZPP A;  4W8R A;  1IDK A;  2XTX A;  1OFM A;  1OGM X;  2VFP A;  4MR0 A;  4URR A;  3RIQ A;  3LJY A;  1KTW A;  1O8I A;  3LYC A;  5JMC B;  3GQ9 A;  2O0W A;  2G0Y A;  2V5I A;  4HWV A;  1HG8 A;  2BM6 A;  1QQ1 A;  3SUC A;  1LLZ A;  2NSP A;  2BX6 A;  1O88 A;  2NTB A;  3GQ7 A;  3DU1 X;  4U4B A;  4OM9 A;  2INV A;  5C1C A;  1TYW A;  1AIR A;  2W7Z A;  4XN0 A;  4YEL A;  4XMY A;  1OFD A;  2NT9 A;  4XKV A;  1DBO A;  1K8F A;  4JRA C;  4XR6 A;  2ODL A;  2QXZ A;  5C1E A;  2VFQ A;  4KH3 A;  4XM3 A;  1NHC A;  2IOU G;  1DAB A;  1EA0 A;  4MXN A;  4YC5 A;  2QX3 A;  4XQF A;  4XN3 A;  1EZG A;  4YEJ A;  1X0C A;  2O04 A;  4YZA A;  3SZE A;  3VMW A;  1BHE A;  4YZQ A;  1OGO X;  3UW0 A;  1LLW A;  4I84 A;  2O0V A;  4OJP A;  4XON A;  1RMG A;  3EQO A;  3LMW A;  2NT6 A;  3PSS A;  4AVZ A;  4EW9 A;  1QRB A;  3SYJ A;  2VBE A;  4XNF A;  2QZA A;  1TYX A;  1VBL A;  4NK6 A;  4OZZ A;  4PMH A;  3VSV A;  2J8K A;  2O17 A;  4U49 A;  4YZX A;  1KCC A;  1PLU A;  1IA5 A;  1RWR A;  4XLF A;  1EE6 A;  1OOC A;  3AK5 A;  1O8M A;  2VFO A;  2XTY A;  2INU A;  3T9G A;  2X6W A;  1K4Z A;  4YZ0 A;  1O8D A;  3VSU A;  2VFM A;  2NST A;  2BSP A;  2NTP A;  2X85 A;  3BH7 B;  2PEC A;  4W8Q A;  4XLE A;  5DNS A;  4Z05 A;  2F3L A;  3SY2 A;  3NB2 A;  4YEI A;  2UVE A;  4NK8 A;  1XG2 A;  4XLA A;  4OPW A;  2BM5 A;  1O8L A;  1O8J A;  2IQ7 A;  2XC1 A;  3EQN A;  2VJI A;  1WXR A;  4XKW A;  1QA1 A;  1QJV A;  1QRC A;  2X3H A;  2VBM A;  3B4N A;  4W8S A;  4XOT A;  3ZSC A;  4YDT A;  2VBK A;  3JUR A;  4Z03 A;  1O8F A;  1RU4 A;  1O8H A;  2O1D A;  2XTW A;  4XLH A;  1L1I A;  1QA2 A;  2EWE A;  3BH6 B;  1KCD A;  1K5C A;  2VFN A;  1QA3 A;  4OJL A;  2B0R A;  1O8E A;  3B8Y A;  1WMR A;  3GRH A;  2NZM A;  1TYU A;  1PE9 A;  2Z8G A;  3P4G A;  4XOP A;  2VJJ A;  3SQV A;  1TSP A;  3FY3 A;  1O8K A;  2NTQ A;  4OJ5 A;  3GQ8 A;  2J8I A;  2QY1 A;  4W8T A;  3PSZ A;  2YUH A;  3PET A;  3VMV A;  4OZY A;  5AMV A;  1OFL A;  1JRG A;  4XOR A;  2XT2 A;  5JLV C;  4C2L A;  2BM4 A;  1H80 A;  1O8G A;  4YCQ A;  1KQ5 A;  2X6X A;  2UVF A;  3N90 A;  3NAW A;  1BN8 A;  1GQ8 A;  4XL9 A;  1OFE A;  1CLW A;  3B90 A;  2BM7 A;  1PXZ A;  4V02 C; 
#chains in the Genus database with same CATH homology
 4JRA C;  3ML3 A;  4OJ6 A;  2VFN A;  2VFO A;  1TYV A;  1QA3 A;  4OJL A;  3AK5 A;  2B0R A;  3P4G A;  2VFQ A;  4KH3 A;  1TYU A;  1K4Z A;  2IOU G;  1DAB A;  1HF2 A;  4OJO A;  1TSP A;  2VFM A;  4OJ5 A;  3BH7 B;  3JX8 A;  2J8I A;  3SZE A;  3N6Z A;  3TH0 A;  2F3L A;  2YUH A;  3PET A;  2VFP A;  3RIQ A;  4OJP A;  3LJY A;  3LYC A;  4OPW A;  5JMC B;  2BM5 A;  1QA2 A;  1QRB A;  5JLV C;  3SYJ A;  2G0Y A;  2V5I A;  2BM4 A;  2XC1 A;  1WXR A;  2BM6 A;  1QA1 A;  1QQ1 A;  1KQ5 A;  1QRC A;  2BX6 A;  1TYX A;  3N90 A;  4OM9 A;  1TYW A;  2W7Z A;  1CLW A;  2BM7 A;  3H09 A;  1K8F A;  4V02 C;  3BH6 B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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