5JMCB

Receptor binding domain of botulinum neurotoxin a in complex with rat sv2c
Total Genus 36
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
36
sequence length
91
structure length
91
Chain Sequence
DKYANFSINFTMENQVHTGMEYDNGRFLGVKFKSVTFKDSVFKSCTFDDVTSVNTYFKNCTFIDTLFENTDFEPYKFIDSEFQNCSFLHNK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title N-linked glycosylation of SV2 is required for binding and uptake of botulinum neurotoxin A.
pubmed doi rcsb
molecule tags Hydrolase
source organism Clostridium botulinum
molecule keywords Botulinum neurotoxin type A
total genus 36
structure length 91
sequence length 91
chains with identical sequence D, F, H
ec nomenclature
pdb deposition date 2016-04-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF13599 Pentapeptide_4 Pentapeptide repeats (9 copies)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.160.20.100 Mainly Beta 3 Solenoid Pectate Lyase C-like Pectate Lyase C-like 5jmcB00
2F3LA 5JLVC 2W7ZA 4JRAC 2J8IA 3N90A 2BM4A 2G0YA 2BM7A 5JMCB 2BM6A 2BM5A
chains in the Genus database with same CATH superfamily
4PMHA 1L1IA 1K5CA 1O8LA 3PETA 3PSZA 3B90A 2UVEA 3P4GA 4XMYA 2O1DA 4YDTA 2EWEA 4Z05A 2BM6A 2QY1A 3NAWA 4XLEA 4XLCA 1DBOA 1JTAA 2VFOA 3B4NA 4XKWA 2VJIA 4HWVA 2XT2A 1JRGA 2VBEA 1DBGA 1K8FA 3KRGA 2O6WA 1PLUA 2X85A 1O8KA 1O88A 3LYCA 3DU1X 4NK6A 4OZZA 4YZXA 5DNSA 2VBMA 1HF2A 4XNFA 1LLWA 3EQNA 1PE9A 1QA1A 1QJVA 2VBKA 2X6WA 3NB2A 1K4ZA 2NT6A 1EA0A 5AMVA 4OPWA 1IB4A 1PXZA 4U4BA 1QCXA 4OJ6A 1EZGA 3VSVA 1VBLA 2VFQA 2NTBA 2NTPA 3N6ZA 1KQ5A 1TYUA 3UW0A 1QRBA 3LJYA 3VSUA 3T9GA 4YEJA 2VFMA 3SY2A 3BH6B 4YC5A 2INVA 4OJ5A 2QX3A 2X3HA 2ODLA 3JX8A 1OFLA 1TYXA 1IDKA 4XQFA 4OM9A 4V02C 1KTWA 2BM7A 2O0WA 1OFEA 3JURA 2IOUG 2VFPA 3GQ9A 2VJJA 4YZAA 1BHEA 3WWGA 2PECA 4OJPA 4YCQA 1TYWA 3SYJA 3ZSCA 4XLHA 4NK8A 4XKVA 1O8IA 2B0RA 4XL9A 2NSPA 2O17A 4C2LA 2BM5A 4U49A 2Z8GA 4JRAC 4W8TA 4YEIA 1X0CA 3H09A 3VSTA 1QA2A 1LLZA 1WXRA 1CZFA 2QYUA 3ML3A 3TH0A 4EW9A 5JLVC 4I84A 4Z06A 4OJLA 2J8IA 3N90A 3SQVA 1XG2A 1CLWA 5JMCB 4YELA 1IDJA 1OGMX 2XTYA 4W8RA 1KCCA 1O8MA 4AVZA 4OZYA 3GQ7A 1TYVA 3EQOA 2BX6A 4XLAA 1NHCA 1QA3A 3SZEA 2NSTA 2XTXA 2VFNA 4XONA 5C1CA 1EE6A 1O8DA 2QXZA 3AK5A 2XC1A 2PYGA 4URRA 5C1EA 2XT4A 4YZQA 1OOCA 1RWRA 1O8FA 2J8KA 1O8EA 3VMVA 1TSPA 3GRHA 4MXNA 4XORA 1O8GA 4W8SA 1IA5A 1BN8A 1OFMA 2UVFA 3BH7B 2INUA 1O8HA 4XOPA 4YFOA 1OGOX 1HG8A 2F3LA 2NZMA 4XR6A 1QRCA 4YZ0A 2YUHA 4W8QA 4XN3A 4XN0A 2V5IA 4MR0A 1H80A 4XM3A 4KH3A 4XOTA 2PYHA 1DABA 3FY3A 2W7ZA 4OJOA 1LM1A 3VMWA 2IQ7A 2BM4A 2BSPA 4Z03A 2XTWA 1OFDA 2X6YA 3GQAA 2NT9A 3SUCA 2O04A 2O0VA 1GQ8A 1RU4A 1WMRA 2QZAA 1KCDA 3PSSA 2X6XA 1QQ1A 1RMGA 3GQ8A 2G0YA 3LMWA 3RIQA 3ZPPA 1O8JA 4XLFA 1AIRA 2NTQA 3B8YA
chains in the Genus database with same CATH topology
1TSPA 1TYUA 5JLVC 1QRBA 3LJYA 3PETA 2J8IA 3N90A 2VFMA 4OJLA 1CLWA 3BH7B 3BH6B 3P4GA 5JMCB 4OJ5A 2BM6A 3JX8A 3ML3A 1TYXA 2F3LA 1QRCA 2VFOA 4OM9A 4V02C 1TYVA 2BM7A 2BX6A 2YUHA 1QA3A 2V5IA 3SZEA 4KH3A 2IOUG 2VFPA 2VFNA 3TH0A 1DABA 4OJOA 1K8FA 2W7ZA 4OJPA 1TYWA 3SYJA 2BM4A 3LYCA 2B0RA 3AK5A 2XC1A 1HF2A 2BM5A 1QA1A 4JRAC 1K4ZA 1QQ1A 3RIQA 2G0YA 4OPWA 3H09A 4OJ6A 1QA2A 2VFQA 1WXRA 3N6ZA 1KQ5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2F3L A;  5JLV C;  2W7Z A;  4JRA C;  2J8I A;  3N90 A;  2BM4 A;  2G0Y A;  2BM7 A;  5JMC B;  2BM6 A;  2BM5 A; 
#chains in the Genus database with same CATH topology
 4PMH A;  1L1I A;  1K5C A;  1O8L A;  3PET A;  3PSZ A;  3B90 A;  2UVE A;  3P4G A;  4XMY A;  2O1D A;  4YDT A;  2EWE A;  4Z05 A;  2BM6 A;  2QY1 A;  3NAW A;  4XLE A;  4XLC A;  1DBO A;  1JTA A;  2VFO A;  3B4N A;  4XKW A;  2VJI A;  4HWV A;  2XT2 A;  1JRG A;  2VBE A;  1DBG A;  1K8F A;  3KRG A;  2O6W A;  1PLU A;  2X85 A;  1O8K A;  1O88 A;  3LYC A;  3DU1 X;  4NK6 A;  4OZZ A;  4YZX A;  5DNS A;  2VBM A;  1HF2 A;  4XNF A;  1LLW A;  3EQN A;  1PE9 A;  1QA1 A;  1QJV A;  2VBK A;  2X6W A;  3NB2 A;  1K4Z A;  2NT6 A;  1EA0 A;  5AMV A;  4OPW A;  1IB4 A;  1PXZ A;  4U4B A;  1QCX A;  4OJ6 A;  1EZG A;  3VSV A;  1VBL A;  2VFQ A;  2NTB A;  2NTP A;  3N6Z A;  1KQ5 A;  1TYU A;  3UW0 A;  1QRB A;  3LJY A;  3VSU A;  3T9G A;  4YEJ A;  2VFM A;  3SY2 A;  3BH6 B;  4YC5 A;  2INV A;  4OJ5 A;  2QX3 A;  2X3H A;  2ODL A;  3JX8 A;  1OFL A;  1TYX A;  1IDK A;  4XQF A;  4OM9 A;  4V02 C;  1KTW A;  2BM7 A;  2O0W A;  1OFE A;  3JUR A;  2IOU G;  2VFP A;  3GQ9 A;  2VJJ A;  4YZA A;  1BHE A;  3WWG A;  2PEC A;  4OJP A;  4YCQ A;  1TYW A;  3SYJ A;  3ZSC A;  4XLH A;  4NK8 A;  4XKV A;  1O8I A;  2B0R A;  4XL9 A;  2NSP A;  2O17 A;  4C2L A;  2BM5 A;  4U49 A;  2Z8G A;  4JRA C;  4W8T A;  4YEI A;  1X0C A;  3H09 A;  3VST A;  1QA2 A;  1LLZ A;  1WXR A;  1CZF A;  2QYU A;  3ML3 A;  3TH0 A;  4EW9 A;  5JLV C;  4I84 A;  4Z06 A;  4OJL A;  2J8I A;  3N90 A;  3SQV A;  1XG2 A;  1CLW A;  5JMC B;  4YEL A;  1IDJ A;  1OGM X;  2XTY A;  4W8R A;  1KCC A;  1O8M A;  4AVZ A;  4OZY A;  3GQ7 A;  1TYV A;  3EQO A;  2BX6 A;  4XLA A;  1NHC A;  1QA3 A;  3SZE A;  2NST A;  2XTX A;  2VFN A;  4XON A;  5C1C A;  1EE6 A;  1O8D A;  2QXZ A;  3AK5 A;  2XC1 A;  2PYG A;  4URR A;  5C1E A;  2XT4 A;  4YZQ A;  1OOC A;  1RWR A;  1O8F A;  2J8K A;  1O8E A;  3VMV A;  1TSP A;  3GRH A;  4MXN A;  4XOR A;  1O8G A;  4W8S A;  1IA5 A;  1BN8 A;  1OFM A;  2UVF A;  3BH7 B;  2INU A;  1O8H A;  4XOP A;  4YFO A;  1OGO X;  1HG8 A;  2F3L A;  2NZM A;  4XR6 A;  1QRC A;  4YZ0 A;  2YUH A;  4W8Q A;  4XN3 A;  4XN0 A;  2V5I A;  4MR0 A;  1H80 A;  4XM3 A;  4KH3 A;  4XOT A;  2PYH A;  1DAB A;  3FY3 A;  2W7Z A;  4OJO A;  1LM1 A;  3VMW A;  2IQ7 A;  2BM4 A;  2BSP A;  4Z03 A;  2XTW A;  1OFD A;  2X6Y A;  3GQA A;  2NT9 A;  3SUC A;  2O04 A;  2O0V A;  1GQ8 A;  1RU4 A;  1WMR A;  2QZA A;  1KCD A;  3PSS A;  2X6X A;  1QQ1 A;  1RMG A;  3GQ8 A;  2G0Y A;  3LMW A;  3RIQ A;  3ZPP A;  1O8J A;  4XLF A;  1AIR A;  2NTQ A;  3B8Y A; 
#chains in the Genus database with same CATH homology
 1TSP A;  1TYU A;  5JLV C;  1QRB A;  3LJY A;  3PET A;  2J8I A;  3N90 A;  2VFM A;  4OJL A;  1CLW A;  3BH7 B;  3BH6 B;  3P4G A;  5JMC B;  4OJ5 A;  2BM6 A;  3JX8 A;  3ML3 A;  1TYX A;  2F3L A;  1QRC A;  2VFO A;  4OM9 A;  4V02 C;  1TYV A;  2BM7 A;  2BX6 A;  2YUH A;  1QA3 A;  2V5I A;  3SZE A;  4KH3 A;  2IOU G;  2VFP A;  2VFN A;  3TH0 A;  1DAB A;  4OJO A;  1K8F A;  2W7Z A;  4OJP A;  1TYW A;  3SYJ A;  2BM4 A;  3LYC A;  2B0R A;  3AK5 A;  2XC1 A;  1HF2 A;  2BM5 A;  1QA1 A;  4JRA C;  1K4Z A;  1QQ1 A;  3RIQ A;  2G0Y A;  4OPW A;  3H09 A;  4OJ6 A;  1QA2 A;  2VFQ A;  1WXR A;  3N6Z A;  1KQ5 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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