1AN1I

Leech-derived tryptase inhibitor/trypsin complex
Total Genus 9
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
9
sequence length
40
structure length
40
Chain Sequence
KVCACPKILKPVCGSDGRTYANSCIARCNGVSIKSEGSCP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of the complex of leech-derived tryptase inhibitor (LDTI) with trypsin and modeling of the LDTI-tryptase system.
pubmed doi rcsb
molecule tags Complex (serine protease/inhibitor)
source organism Sus scrofa
molecule keywords TRYPSIN
total genus 9
structure length 40
sequence length 40
ec nomenclature
pdb deposition date 1997-06-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
I PF00050 Kazal_1 Kazal-type serine protease inhibitor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.60.30 Alpha Beta 2-Layer Sandwich Wheat Germ Agglutinin (Isolectin 2); domain 1 Wheat Germ Agglutinin (Isolectin 2); domain 1 1an1I00
1TGSI 4OVOA 1M8CA 1SGDI 2WCYA 2F3CI 1SGRI 4SGBI 1OYVI 1OMTA 2SGPI 1TIHA 1PJUA 1UUCA 2KMRA 2KCXA 2JYYA 1BMOA 4GI3C 3OVOA 2ERWA 2SGDI 1OMUA 1NUBA 1OVOA 2ARPF 2V53A 2GKRI 1CGJI 3TJQA 2OVOA 3SGBI 1UVFA 2JZMA 1CE3A 1DS3I 1LR9A 1N13A 1IY5A 2GKTI 3HH2C 1M8BA 1YTPA 5JHWC 2SGEI 1CSOI 1AN1I 1IW4A 1TURA 1TBQR 2N17A 3QTLD 1R0RI 2JXDA 2NU1I 1SGNI 2P6AC 1HJAI 3SGQI 1FYBA 1HDLA 1CT2I 1UVGA 5DAEA 2QQDA 1Y1BA 2KMPA 2KMOA 1CT4I 2B0UC 1CGII 1TBRR 1SGYI 2M5XA 2QQCA 1LR7A 1SGPI 2LEOA 3B4VC 1Y1CA 1SGEI 1HPTA 1BUSA 1IY6A 4HGUA 2SGFI 1MT1A 1YU6C 2NU0I 3SEKC 2NU3I 1LR8A 1CHOI 1H0ZA 1PPFI 1SGQI 2N71A 2NU4I 1Z7KB 1DS2I 1TUSA 2BUSA 2KMQA 1KMAA 2SGQI 2N52A 2XRCA 2NU2I 1CT0I 2GKVA 1PCEA
chains in the Genus database with same CATH superfamily
1FARA 1TGSI 4OVOA 1M8CA 1P9GA 1SGDI 1XX6A 2WCYA 2JW6A 3OXGA 2F3CI 1WGTA 2DIPA 5CCLA 5FUVA 1SGRI 4SGBI 1OYVI 1OMTA 2SGPI 1TIHA 2CWGA 2ELIA 1PJUA 1UUCA 2B8TA 1V1HA 2J9RA 2X3TA 2DB6A 2KMRA 3OXLA 1MJBA 5E3PA 2KCXA 4UXHA 1ULNA 2Y0MA 2GIVA 2WGCA 2ODDA 1RFHA 2JYYA 1BMOA 2UVOA 2ENZA 2N1AB 2CJSC 3BJIA 4GI3C 1VDDA 3OL0A 3OVOA 2VRWB 2ERWA 2ORVA 1OMUA 2DKVA 2SGDI 3R5CA 5HQ8A 1FAQA 1KBEA 1W4RA 2L8EA 2LUYA 2L7XA 1NUBA 1OVOA 1PTRA 2ARPF 3PDNA 1K7VA 4UXJA 2V53A 5E3QA 2GKRI 3R5AA 7WGAA 1CGJI 3MEKA 3TJQA 1TOTA 1TBNA 1P9ZA 2OVOA 2OD1A 3VDPA 3SGBI 1UVFA 2JZMA 2V1CC 1CE3A 4MPIA 1DS3I 2OZUA 1LR9A 1N13A 1UHAA 1IY5A 2GKTI 3TOAA 4E1PA 3HH2C 1M8BA 1YTPA 5JHWC 2ROWA 2SGEI 3TO7A 1CSOI 1AN1I 3UEYA 1TURA 3UGIA 1IW4A 3KY9A 1PTQA 3QWPA 1TBQR 2UZ3A 2WVJA 1X4SA 4E1RA 3UOEA 3GOXA 4FKDA 2N17A 1XA6A 2E73A 3UEJA 3QTLD 1R0RI 5HI7A 2JXDA 4WP4A 1FY7A 2NU1I 3E2IA 1SGNI 1Q9BA 2LB7A 4AMLA 1WTJA 1TBOA 1V1IA 2P6AC 1HJAI 3SGQI 1FYBA 1HDLA 2JA1A 1CT2I 1UVGA 3UGDA 2QQ0A 5DAEA 2QQDA 2OU2A 1Y8FA 3UGLA 1U5KA 1Y1BA 2KMPA 2KMOA 1CT4I 5FUWA 3D00A 2B0UC 1CGII 2QQEA 1TBRR 1XBTA 2CWFA 2FNFX 1R79A 5CCMA 5J8CA 1SGYI 2M5XA 2QQCA 1LR7A 1SGPI 4B6DA 2ENNA 2GVIA 2K9HA 2LEOA 1WKXA 3FSYA 1KBFA 2RIJA 5EX0A 1S20A 2PQ8A 1K7TA 1W3SA 2YUUA 3B4VC 3R5BA 3TO9A 3OXFA 3E59A 1ULMA 1Y1CA 3R5DA 4JCVE 4L9MA 1SGEI 1MJAA 2J87A 2X52A 1HPTA 2W0TA 3FC3A 3CXLA 2YQPA 2RC4A 2V1CA 1MJ9A 1BUSA 2CWHA 1IY6A 3VE5A 4HGUA 3TO6A 1K7UA 1HEVA 4A24A 1NXUA 3RU0A 5FUXA 2SGFI 1MT1A 1YU6C 4UXIA 5EX3A 9WGAA 2NU0I 2ORWA 2E5RA 3SEKC 2NU3I 1LR8A 1CHOI 3VDUA 1Z2IA 3QAHA 4DNCA 2QPOA 3FSXA 3TOBA 1H0ZA 1PPFI 1SGQI 2N71A 2NU4I 1Z7KB 5E3RA 1DS2I 1TUSA 2BUSA 2KMQA 1KMAA 2SGQI 2N52A 5FUYA 3UFFA 5J8FA 2XRCA 1WGCA 1X74A 2NU2I 1CT0I 2GKVA 1PCEA 2A20A 1ULKA
chains in the Genus database with same CATH topology
1FARA 1TGSI 4OVOA 1M8CA 1SGDI 1XX6A 2WCYA 2JW6A 3OXGA 2F3CI 2DIPA 5CCLA 5FUVA 1SGRI 4SGBI 1OYVI 1OMTA 2SGPI 1TIHA 2ELIA 1PJUA 1UUCA 2B8TA 1V1HA 2J9RA 2DB6A 2KMRA 3OXLA 2KCXA 4UXHA 2ODDA 1RFHA 2JYYA 1BMOA 2ENZA 2N1AB 2CJSC 3BJIA 4GI3C 1VDDA 3OL0A 3OVOA 2VRWB 2ERWA 2ORVA 1OMUA 2SGDI 5HQ8A 1FAQA 1KBEA 1W4RA 2L8EA 2LUYA 2L7XA 1NUBA 1OVOA 1PTRA 2ARPF 3PDNA 4UXJA 2V53A 2GKRI 1CGJI 3MEKA 3TJQA 1TOTA 1TBNA 2OVOA 2OD1A 3VDPA 3SGBI 1UVFA 2JZMA 2V1CC 1CE3A 1DS3I 1LR9A 1N13A 1IY5A 2GKTI 4E1PA 3HH2C 1M8BA 1YTPA 5JHWC 2ROWA 2SGEI 1CSOI 1AN1I 3UEYA 1TURA 3UGIA 1IW4A 3KY9A 1PTQA 3QWPA 1TBQR 2UZ3A 2WVJA 1X4SA 4E1RA 3GOXA 4FKDA 2N17A 1XA6A 2E73A 3UEJA 3QTLD 1R0RI 5HI7A 2JXDA 2NU1I 3E2IA 1SGNI 1TBOA 1V1IA 2P6AC 1HJAI 3SGQI 1FYBA 1HDLA 2JA1A 1CT2I 1UVGA 3UGDA 2QQ0A 5DAEA 2QQDA 1Y8FA 3UGLA 1U5KA 1Y1BA 2KMPA 2KMOA 1CT4I 5FUWA 3D00A 2B0UC 1CGII 2QQEA 1TBRR 1XBTA 2FNFX 1R79A 5CCMA 1SGYI 2M5XA 2QQCA 1LR7A 1SGPI 4B6DA 2ENNA 2GVIA 2K9HA 2LEOA 1KBFA 5EX0A 2YUUA 1W3SA 3B4VC 3OXFA 3E59A 1Y1CA 4JCVE 4L9MA 1SGEI 2J87A 1HPTA 2W0TA 3FC3A 3CXLA 2YQPA 2V1CA 1BUSA 1IY6A 3VE5A 4HGUA 4A24A 3RU0A 5FUXA 2SGFI 1MT1A 1YU6C 4UXIA 5EX3A 2NU0I 2ORWA 2E5RA 3SEKC 2NU3I 1LR8A 1CHOI 3VDUA 2QPOA 1H0ZA 1PPFI 1SGQI 2N71A 2NU4I 1Z7KB 1DS2I 1TUSA 2BUSA 2KMQA 1KMAA 2SGQI 2N52A 5FUYA 3UFFA 2XRCA 1X74A 2NU2I 1CT0I 2GKVA 1PCEA 2A20A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1TGS I;  4OVO A;  1M8C A;  1SGD I;  2WCY A;  2F3C I;  1SGR I;  4SGB I;  1OYV I;  1OMT A;  2SGP I;  1TIH A;  1PJU A;  1UUC A;  2KMR A;  2KCX A;  2JYY A;  1BMO A;  4GI3 C;  3OVO A;  2ERW A;  2SGD I;  1OMU A;  1NUB A;  1OVO A;  2ARP F;  2V53 A;  2GKR I;  1CGJ I;  3TJQ A;  2OVO A;  3SGB I;  1UVF A;  2JZM A;  1CE3 A;  1DS3 I;  1LR9 A;  1N13 A;  1IY5 A;  2GKT I;  3HH2 C;  1M8B A;  1YTP A;  5JHW C;  2SGE I;  1CSO I;  1AN1 I;  1IW4 A;  1TUR A;  1TBQ R;  2N17 A;  3QTL D;  1R0R I;  2JXD A;  2NU1 I;  1SGN I;  2P6A C;  1HJA I;  3SGQ I;  1FYB A;  1HDL A;  1CT2 I;  1UVG A;  5DAE A;  2QQD A;  1Y1B A;  2KMP A;  2KMO A;  1CT4 I;  2B0U C;  1CGI I;  1TBR R;  1SGY I;  2M5X A;  2QQC A;  1LR7 A;  1SGP I;  2LEO A;  3B4V C;  1Y1C A;  1SGE I;  1HPT A;  1BUS A;  1IY6 A;  4HGU A;  2SGF I;  1MT1 A;  1YU6 C;  2NU0 I;  3SEK C;  2NU3 I;  1LR8 A;  1CHO I;  1H0Z A;  1PPF I;  1SGQ I;  2N71 A;  2NU4 I;  1Z7K B;  1DS2 I;  1TUS A;  2BUS A;  2KMQ A;  1KMA A;  2SGQ I;  2N52 A;  2XRC A;  2NU2 I;  1CT0 I;  2GKV A;  1PCE A; 
#chains in the Genus database with same CATH topology
 1FAR A;  1TGS I;  4OVO A;  1M8C A;  1P9G A;  1SGD I;  1XX6 A;  2WCY A;  2JW6 A;  3OXG A;  2F3C I;  1WGT A;  2DIP A;  5CCL A;  5FUV A;  1SGR I;  4SGB I;  1OYV I;  1OMT A;  2SGP I;  1TIH A;  2CWG A;  2ELI A;  1PJU A;  1UUC A;  2B8T A;  1V1H A;  2J9R A;  2X3T A;  2DB6 A;  2KMR A;  3OXL A;  1MJB A;  5E3P A;  2KCX A;  4UXH A;  1ULN A;  2Y0M A;  2GIV A;  2WGC A;  2ODD A;  1RFH A;  2JYY A;  1BMO A;  2UVO A;  2ENZ A;  2N1A B;  2CJS C;  3BJI A;  4GI3 C;  1VDD A;  3OL0 A;  3OVO A;  2VRW B;  2ERW A;  2ORV A;  1OMU A;  2DKV A;  2SGD I;  3R5C A;  5HQ8 A;  1FAQ A;  1KBE A;  1W4R A;  2L8E A;  2LUY A;  2L7X A;  1NUB A;  1OVO A;  1PTR A;  2ARP F;  3PDN A;  1K7V A;  4UXJ A;  2V53 A;  5E3Q A;  2GKR I;  3R5A A;  7WGA A;  1CGJ I;  3MEK A;  3TJQ A;  1TOT A;  1TBN A;  1P9Z A;  2OVO A;  2OD1 A;  3VDP A;  3SGB I;  1UVF A;  2JZM A;  2V1C C;  1CE3 A;  4MPI A;  1DS3 I;  2OZU A;  1LR9 A;  1N13 A;  1UHA A;  1IY5 A;  2GKT I;  3TOA A;  4E1P A;  3HH2 C;  1M8B A;  1YTP A;  5JHW C;  2ROW A;  2SGE I;  3TO7 A;  1CSO I;  1AN1 I;  3UEY A;  1TUR A;  3UGI A;  1IW4 A;  3KY9 A;  1PTQ A;  3QWP A;  1TBQ R;  2UZ3 A;  2WVJ A;  1X4S A;  4E1R A;  3UOE A;  3GOX A;  4FKD A;  2N17 A;  1XA6 A;  2E73 A;  3UEJ A;  3QTL D;  1R0R I;  5HI7 A;  2JXD A;  4WP4 A;  1FY7 A;  2NU1 I;  3E2I A;  1SGN I;  1Q9B A;  2LB7 A;  4AML A;  1WTJ A;  1TBO A;  1V1I A;  2P6A C;  1HJA I;  3SGQ I;  1FYB A;  1HDL A;  2JA1 A;  1CT2 I;  1UVG A;  3UGD A;  2QQ0 A;  5DAE A;  2QQD A;  2OU2 A;  1Y8F A;  3UGL A;  1U5K A;  1Y1B A;  2KMP A;  2KMO A;  1CT4 I;  5FUW A;  3D00 A;  2B0U C;  1CGI I;  2QQE A;  1TBR R;  1XBT A;  2CWF A;  2FNF X;  1R79 A;  5CCM A;  5J8C A;  1SGY I;  2M5X A;  2QQC A;  1LR7 A;  1SGP I;  4B6D A;  2ENN A;  2GVI A;  2K9H A;  2LEO A;  1WKX A;  3FSY A;  1KBF A;  2RIJ A;  5EX0 A;  1S20 A;  2PQ8 A;  1K7T A;  1W3S A;  2YUU A;  3B4V C;  3R5B A;  3TO9 A;  3OXF A;  3E59 A;  1ULM A;  1Y1C A;  3R5D A;  4JCV E;  4L9M A;  1SGE I;  1MJA A;  2J87 A;  2X52 A;  1HPT A;  2W0T A;  3FC3 A;  3CXL A;  2YQP A;  2RC4 A;  2V1C A;  1MJ9 A;  1BUS A;  2CWH A;  1IY6 A;  3VE5 A;  4HGU A;  3TO6 A;  1K7U A;  1HEV A;  4A24 A;  1NXU A;  3RU0 A;  5FUX A;  2SGF I;  1MT1 A;  1YU6 C;  4UXI A;  5EX3 A;  9WGA A;  2NU0 I;  2ORW A;  2E5R A;  3SEK C;  2NU3 I;  1LR8 A;  1CHO I;  3VDU A;  1Z2I A;  3QAH A;  4DNC A;  2QPO A;  3FSX A;  3TOB A;  1H0Z A;  1PPF I;  1SGQ I;  2N71 A;  2NU4 I;  1Z7K B;  5E3R A;  1DS2 I;  1TUS A;  2BUS A;  2KMQ A;  1KMA A;  2SGQ I;  2N52 A;  5FUY A;  3UFF A;  5J8F A;  2XRC A;  1WGC A;  1X74 A;  2NU2 I;  1CT0 I;  2GKV A;  1PCE A;  2A20 A;  1ULK A; 
#chains in the Genus database with same CATH homology
 1FAR A;  1TGS I;  4OVO A;  1M8C A;  1SGD I;  1XX6 A;  2WCY A;  2JW6 A;  3OXG A;  2F3C I;  2DIP A;  5CCL A;  5FUV A;  1SGR I;  4SGB I;  1OYV I;  1OMT A;  2SGP I;  1TIH A;  2ELI A;  1PJU A;  1UUC A;  2B8T A;  1V1H A;  2J9R A;  2DB6 A;  2KMR A;  3OXL A;  2KCX A;  4UXH A;  2ODD A;  1RFH A;  2JYY A;  1BMO A;  2ENZ A;  2N1A B;  2CJS C;  3BJI A;  4GI3 C;  1VDD A;  3OL0 A;  3OVO A;  2VRW B;  2ERW A;  2ORV A;  1OMU A;  2SGD I;  5HQ8 A;  1FAQ A;  1KBE A;  1W4R A;  2L8E A;  2LUY A;  2L7X A;  1NUB A;  1OVO A;  1PTR A;  2ARP F;  3PDN A;  4UXJ A;  2V53 A;  2GKR I;  1CGJ I;  3MEK A;  3TJQ A;  1TOT A;  1TBN A;  2OVO A;  2OD1 A;  3VDP A;  3SGB I;  1UVF A;  2JZM A;  2V1C C;  1CE3 A;  1DS3 I;  1LR9 A;  1N13 A;  1IY5 A;  2GKT I;  4E1P A;  3HH2 C;  1M8B A;  1YTP A;  5JHW C;  2ROW A;  2SGE I;  1CSO I;  1AN1 I;  3UEY A;  1TUR A;  3UGI A;  1IW4 A;  3KY9 A;  1PTQ A;  3QWP A;  1TBQ R;  2UZ3 A;  2WVJ A;  1X4S A;  4E1R A;  3GOX A;  4FKD A;  2N17 A;  1XA6 A;  2E73 A;  3UEJ A;  3QTL D;  1R0R I;  5HI7 A;  2JXD A;  2NU1 I;  3E2I A;  1SGN I;  1TBO A;  1V1I A;  2P6A C;  1HJA I;  3SGQ I;  1FYB A;  1HDL A;  2JA1 A;  1CT2 I;  1UVG A;  3UGD A;  2QQ0 A;  5DAE A;  2QQD A;  1Y8F A;  3UGL A;  1U5K A;  1Y1B A;  2KMP A;  2KMO A;  1CT4 I;  5FUW A;  3D00 A;  2B0U C;  1CGI I;  2QQE A;  1TBR R;  1XBT A;  2FNF X;  1R79 A;  5CCM A;  1SGY I;  2M5X A;  2QQC A;  1LR7 A;  1SGP I;  4B6D A;  2ENN A;  2GVI A;  2K9H A;  2LEO A;  1KBF A;  5EX0 A;  2YUU A;  1W3S A;  3B4V C;  3OXF A;  3E59 A;  1Y1C A;  4JCV E;  4L9M A;  1SGE I;  2J87 A;  1HPT A;  2W0T A;  3FC3 A;  3CXL A;  2YQP A;  2V1C A;  1BUS A;  1IY6 A;  3VE5 A;  4HGU A;  4A24 A;  3RU0 A;  5FUX A;  2SGF I;  1MT1 A;  1YU6 C;  4UXI A;  5EX3 A;  2NU0 I;  2ORW A;  2E5R A;  3SEK C;  2NU3 I;  1LR8 A;  1CHO I;  3VDU A;  2QPO A;  1H0Z A;  1PPF I;  1SGQ I;  2N71 A;  2NU4 I;  1Z7K B;  1DS2 I;  1TUS A;  2BUS A;  2KMQ A;  1KMA A;  2SGQ I;  2N52 A;  5FUY A;  3UFF A;  2XRC A;  1X74 A;  2NU2 I;  1CT0 I;  2GKV A;  1PCE A;  2A20 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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