2KMQA

Solution structure of intermediate iib of leech-derived tryptase inhibitor, ldti.
Total Genus 5
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
5
sequence length
44
structure length
44
Chain Sequence
KKVCACPKILKPVCGSDGRTYANSCIARCNGVSIKSEGSCPTGI
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase
molecule keywords Leech-derived tryptase inhibitor C
publication title Deciphering the structural basis that guides the oxidative folding of leech-derived tryptase inhibitor.
pubmed doi rcsb
source organism Hirudo medicinalis
total genus 5
structure length 44
sequence length 44
ec nomenclature
pdb deposition date 2009-08-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00050 Kazal_1 Kazal-type serine protease inhibitor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.60.30 Alpha Beta 2-Layer Sandwich Wheat Germ Agglutinin (Isolectin 2); domain 1 Wheat Germ Agglutinin (Isolectin 2); domain 1 2kmqA00
2ARPF 1AN1I 3OVOA 2SGQI 2SGPI 3TJQA 3B4VC 2KCXA 5JHWC 1TBRR 2XRCA 2N71A 2NU0I 1SGDI 1IY5A 1NUBA 1HJAI 1SGPI 1OMUA 1UVFA 1Y1CA 2F3CI 1PPFI 1H0ZA 1PCEA 1DS2I 1CGJI 2KMQA 1TGSI 1CT4I 1KMAA 2NU1I 1OYVI 2SGEI 1CGII 1UUCA 2WCYA 1HDLA 1Y1BA 1BUSA 2LEOA 2NU4I 1N13A 1TBQR 2QQDA 1CSOI 3HH2C 1TIHA 1CHOI 1IW4A 2BUSA 1M8CA 1MT1A 1TUSA 2ERWA 2OVOA 2GKVA 1SGQI 5DAEA 3QTLD 2NU2I 1SGNI 2KMOA 4SGBI 2KMPA 2P6AC 1CT2I 2M5XA 1TURA 1DS3I 1CT0I 2SGFI 1SGRI 4OVOA 1YU6C 1OVOA 2KMRA 1CE3A 1UVGA 1Z7KB 2N52A 1YTPA 2SGDI 2JXDA 1SGEI 1HPTA 2V53A 2B0UC 2GKRI 1LR9A 3SGBI 1R0RI 1OMTA 3SGQI 1LR7A 1IY6A 2NU3I 1BMOA 2QQCA 1FYBA 1M8BA 1PJUA 4GI3C 4HGUA 1LR8A 2GKTI 3SEKC 2JYYA 2N17A 2JZMA 1SGYI
chains in the Genus database with same CATH superfamily
2ARPF 2J87A 1AN1I 3OVOA 3TOBA 5FUWA 2SGQI 3UGIA 2SGPI 1WTJA 3TJQA 3B4VC 3OXGA 2KCXA 1XX6A 2ORVA 2V1CC 3D00A 3R5AA 5JHWC 1U5KA 1TBRR 2XRCA 2N71A 2NU0I 1ULNA 1W4RA 1SGDI 3FC3A 1IY5A 2JA1A 1NUBA 3UOEA 9WGAA 1HJAI 1SGPI 2Y0MA 1OMUA 2VRWB 1W3SA 2YQPA 1UVFA 2OZUA 3TO6A 1Y1CA 2QQEA 2F3CI 1PPFI 2DKVA 4A24A 1X4SA 1PCEA 1DS2I 1CGJI 2KMQA 1TGSI 1H0ZA 1CT4I 1FY7A 1X74A 2GIVA 2NU1I 4UXIA 1OYVI 2SGEI 3FSXA 3TOAA 1VDDA 1CGII 3CXLA 5J8FA 1UUCA 1ULKA 2WCYA 1HDLA 1Y1BA 1BUSA 2FNFX 2L7XA 2LEOA 2ENNA 1Z2IA 2CJSC 2NU4I 2QPOA 3VE5A 1N13A 1TBOA 3VDPA 2YUUA 1TBQR 3UEYA 2QQDA 2DB6A 1TOTA 4L9MA 1CSOI 2CWHA 2WVJA 3HH2C 1TIHA 3E2IA 1CHOI 2LUYA 2RC4A 3KY9A 4E1RA 3UFFA 5FUYA 5E3PA 3R5DA 2J9RA 3RU0A 2ROWA 1IW4A 2K9HA 1Q9BA 5FUVA 1KMAA 2BUSA 1M8CA 1MT1A 1PTQA 2B8TA 3FSYA 3PDNA 1WGCA 2QQ0A 1TUSA 2ERWA 1UHAA 2OVOA 2E5RA 2GKVA 1SGQI 5DAEA 2ELIA 1WGTA 3QTLD 3QAHA 2UZ3A 3QWPA 4B6DA 5J8CA 2A20A 2NU2I 1SGNI 2GVIA 2KMOA 4UXJA 4SGBI 1XA6A 2KMPA 4E1PA 3OXFA 2P6AC 1P9ZA 5CCLA 1CT2I 2M5XA 2ODDA 1KBEA 2OU2A 1TURA 1DS3I 1CT0I 2JW6A 4UXHA 4AMLA 1HEVA 4MPIA 2SGFI 1MJAA 3BJIA 1S20A 2X52A 2CWFA 1SGRI 1V1HA 4OVOA 1YU6C 1OVOA 2ENZA 2KMRA 1CE3A 4WP4A 1UVGA 5FUXA 5CCMA 3R5CA 2UVOA 2DIPA 3OXLA 1Y8FA 4FKDA 1FARA 2E73A 1XBTA 3UGDA 2V1CA 1K7UA 1Z7KB 2N52A 1TBNA 1PTRA 3R5BA 1YTPA 2SGDI 1KBFA 1MJ9A 2JXDA 1SGEI 2L8EA 7WGAA 1HPTA 3GOXA 5E3QA 3VDUA 1MJBA 1K7TA 2V53A 2B0UC 2GKRI 5HI7A 1LR9A 3SGBI 3UGLA 1R0RI 5HQ8A 1ULMA 1OMTA 3SGQI 3MEKA 2OD1A 1LR7A 1NXUA 2NU3I 2W0TA 2X3TA 1IY6A 1K7VA 2RIJA 1BMOA 2QQCA 3E59A 3TO7A 1FYBA 1R79A 1M8BA 5E3RA 1PJUA 2ORWA 4DNCA 1V1IA 2N1AB 3OL0A 1RFHA 4GI3C 4HGUA 1FAQA 1LR8A 4JCVE 2GKTI 2WGCA 5EX0A 3SEKC 2PQ8A 2JYYA 2CWGA 2LB7A 2N17A 2JZMA 1P9GA 5EX3A 1WKXA 1SGYI 3UEJA 3TO9A
chains in the Genus database with same CATH topology
2ARPF 2J87A 1AN1I 3OVOA 5FUWA 2SGQI 3UGIA 2SGPI 3TJQA 3B4VC 3OXGA 2KCXA 1XX6A 2ORVA 2V1CC 3D00A 5JHWC 1U5KA 1TBRR 2XRCA 2N71A 2NU0I 1W4RA 1SGDI 3FC3A 1IY5A 2JA1A 1NUBA 1HJAI 1SGPI 1OMUA 2VRWB 1W3SA 2YQPA 1UVFA 1Y1CA 2QQEA 2F3CI 1PPFI 4A24A 1H0ZA 1X4SA 1PCEA 1DS2I 1CGJI 2KMQA 1TGSI 1CT4I 1X74A 4UXIA 2NU1I 1KMAA 1OYVI 2SGEI 1VDDA 1CGII 3CXLA 1UUCA 2WCYA 1HDLA 1Y1BA 1BUSA 2FNFX 2L7XA 2LEOA 2ENNA 2CJSC 2NU4I 2QPOA 3VE5A 1N13A 1TBOA 3VDPA 2YUUA 1TBQR 3UEYA 2QQDA 2DB6A 1TOTA 4L9MA 1CSOI 2WVJA 3HH2C 1TIHA 3E2IA 1CHOI 2LUYA 3KY9A 4E1RA 3UFFA 5FUYA 2J9RA 3RU0A 2ROWA 1IW4A 2K9HA 5FUVA 2BUSA 1M8CA 1MT1A 1PTQA 2B8TA 3PDNA 2QQ0A 1TUSA 2ERWA 2OVOA 2E5RA 2GKVA 1SGQI 5DAEA 2ELIA 3QTLD 2UZ3A 3QWPA 4B6DA 2A20A 2NU2I 1SGNI 2GVIA 2KMOA 4UXJA 4SGBI 1XA6A 2KMPA 4E1PA 3OXFA 2P6AC 5CCLA 1CT2I 2M5XA 2ODDA 1KBEA 1TURA 1DS3I 1CT0I 2JW6A 4UXHA 2SGFI 3BJIA 1SGRI 1V1HA 4OVOA 1YU6C 1OVOA 2ENZA 2KMRA 1CE3A 1UVGA 5FUXA 5CCMA 2DIPA 3OXLA 1Y8FA 4FKDA 1FARA 2E73A 1XBTA 3UGDA 2V1CA 1Z7KB 2N52A 1TBNA 1PTRA 1YTPA 2SGDI 1KBFA 2JXDA 1SGEI 2L8EA 1HPTA 3GOXA 3VDUA 2V53A 2B0UC 2GKRI 5HI7A 1LR9A 3SGBI 3UGLA 1R0RI 5HQ8A 1OMTA 3SGQI 3MEKA 2OD1A 1LR7A 2W0TA 2NU3I 1IY6A 1BMOA 2QQCA 3E59A 1FYBA 1R79A 1M8BA 1PJUA 2ORWA 1V1IA 2N1AB 3OL0A 1RFHA 4GI3C 4HGUA 1FAQA 1LR8A 4JCVE 2GKTI 5EX0A 3SEKC 2JYYA 2N17A 2JZMA 5EX3A 1SGYI 3UEJA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2ARP F;  1AN1 I;  3OVO A;  2SGQ I;  2SGP I;  3TJQ A;  3B4V C;  2KCX A;  5JHW C;  1TBR R;  2XRC A;  2N71 A;  2NU0 I;  1SGD I;  1IY5 A;  1NUB A;  1HJA I;  1SGP I;  1OMU A;  1UVF A;  1Y1C A;  2F3C I;  1PPF I;  1H0Z A;  1PCE A;  1DS2 I;  1CGJ I;  2KMQ A;  1TGS I;  1CT4 I;  1KMA A;  2NU1 I;  1OYV I;  2SGE I;  1CGI I;  1UUC A;  2WCY A;  1HDL A;  1Y1B A;  1BUS A;  2LEO A;  2NU4 I;  1N13 A;  1TBQ R;  2QQD A;  1CSO I;  3HH2 C;  1TIH A;  1CHO I;  1IW4 A;  2BUS A;  1M8C A;  1MT1 A;  1TUS A;  2ERW A;  2OVO A;  2GKV A;  1SGQ I;  5DAE A;  3QTL D;  2NU2 I;  1SGN I;  2KMO A;  4SGB I;  2KMP A;  2P6A C;  1CT2 I;  2M5X A;  1TUR A;  1DS3 I;  1CT0 I;  2SGF I;  1SGR I;  4OVO A;  1YU6 C;  1OVO A;  2KMR A;  1CE3 A;  1UVG A;  1Z7K B;  2N52 A;  1YTP A;  2SGD I;  2JXD A;  1SGE I;  1HPT A;  2V53 A;  2B0U C;  2GKR I;  1LR9 A;  3SGB I;  1R0R I;  1OMT A;  3SGQ I;  1LR7 A;  1IY6 A;  2NU3 I;  1BMO A;  2QQC A;  1FYB A;  1M8B A;  1PJU A;  4GI3 C;  4HGU A;  1LR8 A;  2GKT I;  3SEK C;  2JYY A;  2N17 A;  2JZM A;  1SGY I; 
#chains in the Genus database with same CATH topology
 2ARP F;  2J87 A;  1AN1 I;  3OVO A;  3TOB A;  5FUW A;  2SGQ I;  3UGI A;  2SGP I;  1WTJ A;  3TJQ A;  3B4V C;  3OXG A;  2KCX A;  1XX6 A;  2ORV A;  2V1C C;  3D00 A;  3R5A A;  5JHW C;  1U5K A;  1TBR R;  2XRC A;  2N71 A;  2NU0 I;  1ULN A;  1W4R A;  1SGD I;  3FC3 A;  1IY5 A;  2JA1 A;  1NUB A;  3UOE A;  9WGA A;  1HJA I;  1SGP I;  2Y0M A;  1OMU A;  2VRW B;  1W3S A;  2YQP A;  1UVF A;  2OZU A;  3TO6 A;  1Y1C A;  2QQE A;  2F3C I;  1PPF I;  2DKV A;  4A24 A;  1X4S A;  1PCE A;  1DS2 I;  1CGJ I;  2KMQ A;  1TGS I;  1H0Z A;  1CT4 I;  1FY7 A;  1X74 A;  2GIV A;  2NU1 I;  4UXI A;  1OYV I;  2SGE I;  3FSX A;  3TOA A;  1VDD A;  1CGI I;  3CXL A;  5J8F A;  1UUC A;  1ULK A;  2WCY A;  1HDL A;  1Y1B A;  1BUS A;  2FNF X;  2L7X A;  2LEO A;  2ENN A;  1Z2I A;  2CJS C;  2NU4 I;  2QPO A;  3VE5 A;  1N13 A;  1TBO A;  3VDP A;  2YUU A;  1TBQ R;  3UEY A;  2QQD A;  2DB6 A;  1TOT A;  4L9M A;  1CSO I;  2CWH A;  2WVJ A;  3HH2 C;  1TIH A;  3E2I A;  1CHO I;  2LUY A;  2RC4 A;  3KY9 A;  4E1R A;  3UFF A;  5FUY A;  5E3P A;  3R5D A;  2J9R A;  3RU0 A;  2ROW A;  1IW4 A;  2K9H A;  1Q9B A;  5FUV A;  1KMA A;  2BUS A;  1M8C A;  1MT1 A;  1PTQ A;  2B8T A;  3FSY A;  3PDN A;  1WGC A;  2QQ0 A;  1TUS A;  2ERW A;  1UHA A;  2OVO A;  2E5R A;  2GKV A;  1SGQ I;  5DAE A;  2ELI A;  1WGT A;  3QTL D;  3QAH A;  2UZ3 A;  3QWP A;  4B6D A;  5J8C A;  2A20 A;  2NU2 I;  1SGN I;  2GVI A;  2KMO A;  4UXJ A;  4SGB I;  1XA6 A;  2KMP A;  4E1P A;  3OXF A;  2P6A C;  1P9Z A;  5CCL A;  1CT2 I;  2M5X A;  2ODD A;  1KBE A;  2OU2 A;  1TUR A;  1DS3 I;  1CT0 I;  2JW6 A;  4UXH A;  4AML A;  1HEV A;  4MPI A;  2SGF I;  1MJA A;  3BJI A;  1S20 A;  2X52 A;  2CWF A;  1SGR I;  1V1H A;  4OVO A;  1YU6 C;  1OVO A;  2ENZ A;  2KMR A;  1CE3 A;  4WP4 A;  1UVG A;  5FUX A;  5CCM A;  3R5C A;  2UVO A;  2DIP A;  3OXL A;  1Y8F A;  4FKD A;  1FAR A;  2E73 A;  1XBT A;  3UGD A;  2V1C A;  1K7U A;  1Z7K B;  2N52 A;  1TBN A;  1PTR A;  3R5B A;  1YTP A;  2SGD I;  1KBF A;  1MJ9 A;  2JXD A;  1SGE I;  2L8E A;  7WGA A;  1HPT A;  3GOX A;  5E3Q A;  3VDU A;  1MJB A;  1K7T A;  2V53 A;  2B0U C;  2GKR I;  5HI7 A;  1LR9 A;  3SGB I;  3UGL A;  1R0R I;  5HQ8 A;  1ULM A;  1OMT A;  3SGQ I;  3MEK A;  2OD1 A;  1LR7 A;  1NXU A;  2NU3 I;  2W0T A;  2X3T A;  1IY6 A;  1K7V A;  2RIJ A;  1BMO A;  2QQC A;  3E59 A;  3TO7 A;  1FYB A;  1R79 A;  1M8B A;  5E3R A;  1PJU A;  2ORW A;  4DNC A;  1V1I A;  2N1A B;  3OL0 A;  1RFH A;  4GI3 C;  4HGU A;  1FAQ A;  1LR8 A;  4JCV E;  2GKT I;  2WGC A;  5EX0 A;  3SEK C;  2PQ8 A;  2JYY A;  2CWG A;  2LB7 A;  2N17 A;  2JZM A;  1P9G A;  5EX3 A;  1WKX A;  1SGY I;  3UEJ A;  3TO9 A; 
#chains in the Genus database with same CATH homology
 2ARP F;  2J87 A;  1AN1 I;  3OVO A;  5FUW A;  2SGQ I;  3UGI A;  2SGP I;  3TJQ A;  3B4V C;  3OXG A;  2KCX A;  1XX6 A;  2ORV A;  2V1C C;  3D00 A;  5JHW C;  1U5K A;  1TBR R;  2XRC A;  2N71 A;  2NU0 I;  1W4R A;  1SGD I;  3FC3 A;  1IY5 A;  2JA1 A;  1NUB A;  1HJA I;  1SGP I;  1OMU A;  2VRW B;  1W3S A;  2YQP A;  1UVF A;  1Y1C A;  2QQE A;  2F3C I;  1PPF I;  4A24 A;  1H0Z A;  1X4S A;  1PCE A;  1DS2 I;  1CGJ I;  2KMQ A;  1TGS I;  1CT4 I;  1X74 A;  4UXI A;  2NU1 I;  1KMA A;  1OYV I;  2SGE I;  1VDD A;  1CGI I;  3CXL A;  1UUC A;  2WCY A;  1HDL A;  1Y1B A;  1BUS A;  2FNF X;  2L7X A;  2LEO A;  2ENN A;  2CJS C;  2NU4 I;  2QPO A;  3VE5 A;  1N13 A;  1TBO A;  3VDP A;  2YUU A;  1TBQ R;  3UEY A;  2QQD A;  2DB6 A;  1TOT A;  4L9M A;  1CSO I;  2WVJ A;  3HH2 C;  1TIH A;  3E2I A;  1CHO I;  2LUY A;  3KY9 A;  4E1R A;  3UFF A;  5FUY A;  2J9R A;  3RU0 A;  2ROW A;  1IW4 A;  2K9H A;  5FUV A;  2BUS A;  1M8C A;  1MT1 A;  1PTQ A;  2B8T A;  3PDN A;  2QQ0 A;  1TUS A;  2ERW A;  2OVO A;  2E5R A;  2GKV A;  1SGQ I;  5DAE A;  2ELI A;  3QTL D;  2UZ3 A;  3QWP A;  4B6D A;  2A20 A;  2NU2 I;  1SGN I;  2GVI A;  2KMO A;  4UXJ A;  4SGB I;  1XA6 A;  2KMP A;  4E1P A;  3OXF A;  2P6A C;  5CCL A;  1CT2 I;  2M5X A;  2ODD A;  1KBE A;  1TUR A;  1DS3 I;  1CT0 I;  2JW6 A;  4UXH A;  2SGF I;  3BJI A;  1SGR I;  1V1H A;  4OVO A;  1YU6 C;  1OVO A;  2ENZ A;  2KMR A;  1CE3 A;  1UVG A;  5FUX A;  5CCM A;  2DIP A;  3OXL A;  1Y8F A;  4FKD A;  1FAR A;  2E73 A;  1XBT A;  3UGD A;  2V1C A;  1Z7K B;  2N52 A;  1TBN A;  1PTR A;  1YTP A;  2SGD I;  1KBF A;  2JXD A;  1SGE I;  2L8E A;  1HPT A;  3GOX A;  3VDU A;  2V53 A;  2B0U C;  2GKR I;  5HI7 A;  1LR9 A;  3SGB I;  3UGL A;  1R0R I;  5HQ8 A;  1OMT A;  3SGQ I;  3MEK A;  2OD1 A;  1LR7 A;  2W0T A;  2NU3 I;  1IY6 A;  1BMO A;  2QQC A;  3E59 A;  1FYB A;  1R79 A;  1M8B A;  1PJU A;  2ORW A;  1V1I A;  2N1A B;  3OL0 A;  1RFH A;  4GI3 C;  4HGU A;  1FAQ A;  1LR8 A;  4JCV E;  2GKT I;  5EX0 A;  3SEK C;  2JYY A;  2N17 A;  2JZM A;  5EX3 A;  1SGY I;  3UEJ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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