2KMQA

Solution structure of intermediate iib of leech-derived tryptase inhibitor, ldti.
Total Genus 5
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
5
sequence length
44
structure length
44
Chain Sequence
KKVCACPKILKPVCGSDGRTYANSCIARCNGVSIKSEGSCPTGI
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Leech-derived tryptase inhibitor C
publication title Deciphering the structural basis that guides the oxidative folding of leech-derived tryptase inhibitor.
pubmed doi rcsb
source organism Hirudo medicinalis
molecule tags Hydrolase
total genus 5
structure length 44
sequence length 44
ec nomenclature
pdb deposition date 2009-08-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00050 Kazal_1 Kazal-type serine protease inhibitor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.60.30 Alpha Beta 2-Layer Sandwich Wheat Germ Agglutinin (Isolectin 2); domain 1 Wheat Germ Agglutinin (Isolectin 2); domain 1 2kmqA00
2KMQA 2SGQI 1N13A 2SGEI 1AN1I 2GKRI 1CT0I 2N17A 1TGSI 2ERWA 5DAEA 1OMUA 1UUCA 1CE3A 1SGYI 3QTLD 2V53A 2NU3I 2WCYA 1HJAI 1BMOA 2KMRA 1PPFI 1CHOI 1R0RI 1DS2I 4SGBI 1SGEI 1SGRI 2KMPA 1LR9A 1TUSA 2N52A 1KMAA 1Z7KB 1IY6A 1SGDI 1LR8A 2BUSA 3TJQA 1CT4I 1CGJI 4HGUA 2JXDA 3SEKC 1HDLA 3SGQI 2SGDI 1TIHA 1Y1BA 1YTPA 1H0ZA 1TBRR 2N71A 1UVGA 1SGQI 1TBQR 2SGFI 3B4VC 1DS3I 1TURA 1CT2I 1Y1CA 3HH2C 2QQDA 1FYBA 1M8CA 5JHWC 1BUSA 1PCEA 2GKTI 3SGBI 1M8BA 2KMOA 2NU2I 1SGPI 1LR7A 2SGPI 2KCXA 2XRCA 1OMTA 1OYVI 2GKVA 2P6AC 1CSOI 4GI3C 4OVOA 1UVFA 2B0UC 2QQCA 1OVOA 1SGNI 1MT1A 2ARPF 1IY5A 1CGII 2NU4I 1IW4A 1PJUA 1HPTA 1NUBA 2JYYA 2JZMA 2F3CI 2LEOA 2M5XA 3OVOA 2NU1I 1YU6C 2OVOA 2NU0I
chains in the Genus database with same CATH superfamily
2KMQA 2SGQI 1N13A 3MEKA 1ULNA 2SGEI 5FUWA 1AN1I 2GKRI 2DB6A 2UZ3A 3OXLA 5E3QA 3UFFA 5E3PA 1WGTA 1CT0I 2N17A 1TGSI 2ERWA 3CXLA 5DAEA 1OMUA 1P9ZA 1UUCA 1UHAA 2B8TA 1PTQA 2DKVA 2GVIA 3OL0A 3QAHA 1CE3A 1SGYI 2ENNA 2LB7A 3QTLD 3E59A 3R5CA 2ENZA 2ROWA 2V53A 1KBFA 2NU3I 2WCYA 5HQ8A 1HJAI 1BMOA 9WGAA 5FUVA 3VE5A 2UVOA 2KMRA 2L7XA 4UXIA 1PPFI 3RU0A 2QQ0A 1CHOI 1X4SA 2CJSC 1R0RI 3BJIA 3D00A 4DNCA 2W0TA 4UXHA 2WGCA 1DS2I 3R5AA 1SGEI 4SGBI 1SGRI 5FUXA 3E2IA 1XBTA 2E5RA 3PDNA 1FARA 4B6DA 2KMPA 1X74A 3KY9A 1LR9A 1TUSA 2N52A 1KMAA 2ORVA 4WP4A 1Z7KB 1KBEA 1V1HA 1SGDI 1W4RA 1WKXA 1WTJA 1XX6A 2E73A 1U5KA 3FSYA 1LR8A 2BUSA 1XA6A 1K7VA 3TJQA 1Y8FA 4UXJA 1S20A 4A24A 2V1CC 3GOXA 1CT4I 1CGJI 4HGUA 2JXDA 3SEKC 4E1PA 3TO6A 1HDLA 4L9MA 1Z2IA 4MPIA 2OD1A 2V1CA 2Y0MA 1HEVA 1FY7A 3SGQI 2SGDI 1TIHA 1FAQA 1Y1BA 5EX0A 1YTPA 1H0ZA 1TBRR 5E3RA 2X52A 2FNFX 2RIJA 1VDDA 3TOBA 2N71A 3R5BA 3TO7A 1UVGA 2L8EA 1SGQI 1V1IA 1TBQR 2CWGA 2SGFI 3QWPA 3B4VC 3VDPA 5J8FA 2OU2A 1R79A 1DS3I 1TBOA 1CT2I 1TURA 2GIVA 3UOEA 1MJ9A 4FKDA 1Y1CA 3TO9A 2JW6A 3HH2C 1PTRA 1TBNA 1TOTA 3OXFA 3UGDA 2QQDA 7WGAA 1FYBA 1M8CA 5JHWC 2N1AB 2YUUA 1PCEA 2GKTI 1BUSA 5CCLA 5HI7A 3SGBI 1M8BA 2KMOA 3R5DA 2X3TA 2NU2I 1SGPI 1LR7A 2RC4A 2LUYA 2SGPI 2KCXA 2XRCA 3OXGA 1OMTA 2ELIA 5FUYA 3UGLA 1OYVI 2GKVA 1NXUA 2P6AC 4JCVE 2CWFA 1CSOI 3UEJA 4GI3C 3FC3A 1MJBA 1UVFA 4OVOA 2WVJA 1IY6A 4E1RA 2B0UC 1P9GA 3UGIA 2QQCA 1OVOA 1SGNI 5EX3A 2DIPA 3FSXA 4AMLA 2A20A 2J87A 1MT1A 2ARPF 1IY5A 2ORWA 1CGII 2CWHA 3TOAA 5J8CA 2NU4I 1Q9BA 1IW4A 1PJUA 2YQPA 1HPTA 1NUBA 2JYYA 2JZMA 2F3CI 1MJAA 1K7TA 1WGCA 2QPOA 3VDUA 2JA1A 2K9HA 2LEOA 2VRWB 2M5XA 2PQ8A 1RFHA 5CCMA 2ODDA 2OZUA 1K7UA 3OVOA 2NU1I 1ULKA 1YU6C 1ULMA 1W3SA 2QQEA 2OVOA 2J9RA 2NU0I 3UEYA
chains in the Genus database with same CATH topology
2KMQA 2SGQI 1N13A 3MEKA 2SGEI 5FUWA 1AN1I 2GKRI 2DB6A 2UZ3A 3OXLA 3UFFA 1CT0I 2N17A 1TGSI 2ERWA 3CXLA 5DAEA 1OMUA 1UUCA 2B8TA 1PTQA 2GVIA 3OL0A 1CE3A 1SGYI 2ENNA 3QTLD 3E59A 2ENZA 2ROWA 2V53A 1KBFA 2NU3I 2WCYA 5HQ8A 1HJAI 1BMOA 5FUVA 3VE5A 2KMRA 2L7XA 4UXIA 1PPFI 3RU0A 2QQ0A 1CHOI 1X4SA 2CJSC 1R0RI 3BJIA 3D00A 2W0TA 4UXHA 5FUXA 1DS2I 4SGBI 1SGEI 1SGRI 3E2IA 1XBTA 2E5RA 3PDNA 1FARA 4B6DA 2KMPA 1X74A 3KY9A 1LR9A 1TUSA 2N52A 1KMAA 2ORVA 1Z7KB 1KBEA 1V1HA 1SGDI 1W4RA 1XX6A 1IY6A 2E73A 1U5KA 1LR8A 2BUSA 1XA6A 3TJQA 1Y8FA 4UXJA 4A24A 3GOXA 2V1CC 1CT4I 1CGJI 4HGUA 2JXDA 3SEKC 4E1PA 1HDLA 4L9MA 2OD1A 2V1CA 3SGQI 2SGDI 1TIHA 1FAQA 1Y1BA 5EX0A 1YTPA 1H0ZA 1TBRR 2FNFX 1VDDA 2N71A 1UVGA 2L8EA 1SGQI 1V1IA 1TBQR 2SGFI 3QWPA 3VDPA 3B4VC 1R79A 1DS3I 1TBOA 1CT2I 1TURA 4FKDA 1Y1CA 2JW6A 3HH2C 1PTRA 1TBNA 1TOTA 3OXFA 3UGDA 2QQDA 1FYBA 1M8CA 5JHWC 2N1AB 2YUUA 1PCEA 2GKTI 1BUSA 5CCLA 5HI7A 3SGBI 1M8BA 2KMOA 2NU2I 1SGPI 1LR7A 2LUYA 2SGPI 2KCXA 2XRCA 3OXGA 1OMTA 2ELIA 5FUYA 3UGLA 1OYVI 2GKVA 2P6AC 4JCVE 1CSOI 3UEJA 4GI3C 3FC3A 4OVOA 1UVFA 2WVJA 4E1RA 2B0UC 3UGIA 2QQCA 1OVOA 1SGNI 5EX3A 2DIPA 2A20A 2J87A 1MT1A 2ARPF 1IY5A 2ORWA 1CGII 2NU4I 1IW4A 1PJUA 2YQPA 1HPTA 1NUBA 2JYYA 2JZMA 2F3CI 2QPOA 3VDUA 2JA1A 2K9HA 2LEOA 2VRWB 2M5XA 5CCMA 1RFHA 2ODDA 3OVOA 2NU1I 1YU6C 1W3SA 2QQEA 2OVOA 2J9RA 2NU0I 3UEYA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2KMQ A;  2SGQ I;  1N13 A;  2SGE I;  1AN1 I;  2GKR I;  1CT0 I;  2N17 A;  1TGS I;  2ERW A;  5DAE A;  1OMU A;  1UUC A;  1CE3 A;  1SGY I;  3QTL D;  2V53 A;  2NU3 I;  2WCY A;  1HJA I;  1BMO A;  2KMR A;  1PPF I;  1CHO I;  1R0R I;  1DS2 I;  4SGB I;  1SGE I;  1SGR I;  2KMP A;  1LR9 A;  1TUS A;  2N52 A;  1KMA A;  1Z7K B;  1IY6 A;  1SGD I;  1LR8 A;  2BUS A;  3TJQ A;  1CT4 I;  1CGJ I;  4HGU A;  2JXD A;  3SEK C;  1HDL A;  3SGQ I;  2SGD I;  1TIH A;  1Y1B A;  1YTP A;  1H0Z A;  1TBR R;  2N71 A;  1UVG A;  1SGQ I;  1TBQ R;  2SGF I;  3B4V C;  1DS3 I;  1TUR A;  1CT2 I;  1Y1C A;  3HH2 C;  2QQD A;  1FYB A;  1M8C A;  5JHW C;  1BUS A;  1PCE A;  2GKT I;  3SGB I;  1M8B A;  2KMO A;  2NU2 I;  1SGP I;  1LR7 A;  2SGP I;  2KCX A;  2XRC A;  1OMT A;  1OYV I;  2GKV A;  2P6A C;  1CSO I;  4GI3 C;  4OVO A;  1UVF A;  2B0U C;  2QQC A;  1OVO A;  1SGN I;  1MT1 A;  2ARP F;  1IY5 A;  1CGI I;  2NU4 I;  1IW4 A;  1PJU A;  1HPT A;  1NUB A;  2JYY A;  2JZM A;  2F3C I;  2LEO A;  2M5X A;  3OVO A;  2NU1 I;  1YU6 C;  2OVO A;  2NU0 I; 
#chains in the Genus database with same CATH topology
 2KMQ A;  2SGQ I;  1N13 A;  3MEK A;  1ULN A;  2SGE I;  5FUW A;  1AN1 I;  2GKR I;  2DB6 A;  2UZ3 A;  3OXL A;  5E3Q A;  3UFF A;  5E3P A;  1WGT A;  1CT0 I;  2N17 A;  1TGS I;  2ERW A;  3CXL A;  5DAE A;  1OMU A;  1P9Z A;  1UUC A;  1UHA A;  2B8T A;  1PTQ A;  2DKV A;  2GVI A;  3OL0 A;  3QAH A;  1CE3 A;  1SGY I;  2ENN A;  2LB7 A;  3QTL D;  3E59 A;  3R5C A;  2ENZ A;  2ROW A;  2V53 A;  1KBF A;  2NU3 I;  2WCY A;  5HQ8 A;  1HJA I;  1BMO A;  9WGA A;  5FUV A;  3VE5 A;  2UVO A;  2KMR A;  2L7X A;  4UXI A;  1PPF I;  3RU0 A;  2QQ0 A;  1CHO I;  1X4S A;  2CJS C;  1R0R I;  3BJI A;  3D00 A;  4DNC A;  2W0T A;  4UXH A;  2WGC A;  1DS2 I;  3R5A A;  1SGE I;  4SGB I;  1SGR I;  5FUX A;  3E2I A;  1XBT A;  2E5R A;  3PDN A;  1FAR A;  4B6D A;  2KMP A;  1X74 A;  3KY9 A;  1LR9 A;  1TUS A;  2N52 A;  1KMA A;  2ORV A;  4WP4 A;  1Z7K B;  1KBE A;  1V1H A;  1SGD I;  1W4R A;  1WKX A;  1WTJ A;  1XX6 A;  2E73 A;  1U5K A;  3FSY A;  1LR8 A;  2BUS A;  1XA6 A;  1K7V A;  3TJQ A;  1Y8F A;  4UXJ A;  1S20 A;  4A24 A;  2V1C C;  3GOX A;  1CT4 I;  1CGJ I;  4HGU A;  2JXD A;  3SEK C;  4E1P A;  3TO6 A;  1HDL A;  4L9M A;  1Z2I A;  4MPI A;  2OD1 A;  2V1C A;  2Y0M A;  1HEV A;  1FY7 A;  3SGQ I;  2SGD I;  1TIH A;  1FAQ A;  1Y1B A;  5EX0 A;  1YTP A;  1H0Z A;  1TBR R;  5E3R A;  2X52 A;  2FNF X;  2RIJ A;  1VDD A;  3TOB A;  2N71 A;  3R5B A;  3TO7 A;  1UVG A;  2L8E A;  1SGQ I;  1V1I A;  1TBQ R;  2CWG A;  2SGF I;  3QWP A;  3B4V C;  3VDP A;  5J8F A;  2OU2 A;  1R79 A;  1DS3 I;  1TBO A;  1CT2 I;  1TUR A;  2GIV A;  3UOE A;  1MJ9 A;  4FKD A;  1Y1C A;  3TO9 A;  2JW6 A;  3HH2 C;  1PTR A;  1TBN A;  1TOT A;  3OXF A;  3UGD A;  2QQD A;  7WGA A;  1FYB A;  1M8C A;  5JHW C;  2N1A B;  2YUU A;  1PCE A;  2GKT I;  1BUS A;  5CCL A;  5HI7 A;  3SGB I;  1M8B A;  2KMO A;  3R5D A;  2X3T A;  2NU2 I;  1SGP I;  1LR7 A;  2RC4 A;  2LUY A;  2SGP I;  2KCX A;  2XRC A;  3OXG A;  1OMT A;  2ELI A;  5FUY A;  3UGL A;  1OYV I;  2GKV A;  1NXU A;  2P6A C;  4JCV E;  2CWF A;  1CSO I;  3UEJ A;  4GI3 C;  3FC3 A;  1MJB A;  1UVF A;  4OVO A;  2WVJ A;  1IY6 A;  4E1R A;  2B0U C;  1P9G A;  3UGI A;  2QQC A;  1OVO A;  1SGN I;  5EX3 A;  2DIP A;  3FSX A;  4AML A;  2A20 A;  2J87 A;  1MT1 A;  2ARP F;  1IY5 A;  2ORW A;  1CGI I;  2CWH A;  3TOA A;  5J8C A;  2NU4 I;  1Q9B A;  1IW4 A;  1PJU A;  2YQP A;  1HPT A;  1NUB A;  2JYY A;  2JZM A;  2F3C I;  1MJA A;  1K7T A;  1WGC A;  2QPO A;  3VDU A;  2JA1 A;  2K9H A;  2LEO A;  2VRW B;  2M5X A;  2PQ8 A;  1RFH A;  5CCM A;  2ODD A;  2OZU A;  1K7U A;  3OVO A;  2NU1 I;  1ULK A;  1YU6 C;  1ULM A;  1W3S A;  2QQE A;  2OVO A;  2J9R A;  2NU0 I;  3UEY A; 
#chains in the Genus database with same CATH homology
 2KMQ A;  2SGQ I;  1N13 A;  3MEK A;  2SGE I;  5FUW A;  1AN1 I;  2GKR I;  2DB6 A;  2UZ3 A;  3OXL A;  3UFF A;  1CT0 I;  2N17 A;  1TGS I;  2ERW A;  3CXL A;  5DAE A;  1OMU A;  1UUC A;  2B8T A;  1PTQ A;  2GVI A;  3OL0 A;  1CE3 A;  1SGY I;  2ENN A;  3QTL D;  3E59 A;  2ENZ A;  2ROW A;  2V53 A;  1KBF A;  2NU3 I;  2WCY A;  5HQ8 A;  1HJA I;  1BMO A;  5FUV A;  3VE5 A;  2KMR A;  2L7X A;  4UXI A;  1PPF I;  3RU0 A;  2QQ0 A;  1CHO I;  1X4S A;  2CJS C;  1R0R I;  3BJI A;  3D00 A;  2W0T A;  4UXH A;  5FUX A;  1DS2 I;  4SGB I;  1SGE I;  1SGR I;  3E2I A;  1XBT A;  2E5R A;  3PDN A;  1FAR A;  4B6D A;  2KMP A;  1X74 A;  3KY9 A;  1LR9 A;  1TUS A;  2N52 A;  1KMA A;  2ORV A;  1Z7K B;  1KBE A;  1V1H A;  1SGD I;  1W4R A;  1XX6 A;  1IY6 A;  2E73 A;  1U5K A;  1LR8 A;  2BUS A;  1XA6 A;  3TJQ A;  1Y8F A;  4UXJ A;  4A24 A;  3GOX A;  2V1C C;  1CT4 I;  1CGJ I;  4HGU A;  2JXD A;  3SEK C;  4E1P A;  1HDL A;  4L9M A;  2OD1 A;  2V1C A;  3SGQ I;  2SGD I;  1TIH A;  1FAQ A;  1Y1B A;  5EX0 A;  1YTP A;  1H0Z A;  1TBR R;  2FNF X;  1VDD A;  2N71 A;  1UVG A;  2L8E A;  1SGQ I;  1V1I A;  1TBQ R;  2SGF I;  3QWP A;  3VDP A;  3B4V C;  1R79 A;  1DS3 I;  1TBO A;  1CT2 I;  1TUR A;  4FKD A;  1Y1C A;  2JW6 A;  3HH2 C;  1PTR A;  1TBN A;  1TOT A;  3OXF A;  3UGD A;  2QQD A;  1FYB A;  1M8C A;  5JHW C;  2N1A B;  2YUU A;  1PCE A;  2GKT I;  1BUS A;  5CCL A;  5HI7 A;  3SGB I;  1M8B A;  2KMO A;  2NU2 I;  1SGP I;  1LR7 A;  2LUY A;  2SGP I;  2KCX A;  2XRC A;  3OXG A;  1OMT A;  2ELI A;  5FUY A;  3UGL A;  1OYV I;  2GKV A;  2P6A C;  4JCV E;  1CSO I;  3UEJ A;  4GI3 C;  3FC3 A;  4OVO A;  1UVF A;  2WVJ A;  4E1R A;  2B0U C;  3UGI A;  2QQC A;  1OVO A;  1SGN I;  5EX3 A;  2DIP A;  2A20 A;  2J87 A;  1MT1 A;  2ARP F;  1IY5 A;  2ORW A;  1CGI I;  2NU4 I;  1IW4 A;  1PJU A;  2YQP A;  1HPT A;  1NUB A;  2JYY A;  2JZM A;  2F3C I;  2QPO A;  3VDU A;  2JA1 A;  2K9H A;  2LEO A;  2VRW B;  2M5X A;  5CCM A;  1RFH A;  2ODD A;  3OVO A;  2NU1 I;  1YU6 C;  1W3S A;  2QQE A;  2OVO A;  2J9R A;  2NU0 I;  3UEY A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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