2LEOA

Solution structure of esophageal cancer-related gene 2
Total Genus 14
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
14
sequence length
66
structure length
66
Chain Sequence
SEAASLSPKKVDCSIYKKYPVVAIPCPITYLPVCGSDYITYGNECHLCTESLKSNGRVQFLHDGSC
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title NMR structure note: human esophageal cancer-related gene 2
pubmed doi rcsb
molecule tags Hydrolase inhibitor
source organism Homo sapiens
molecule keywords Serine protease inhibitor Kazal-type 7
total genus 14
structure length 66
sequence length 66
ec nomenclature
pdb deposition date 2011-06-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00050 Kazal_1 Kazal-type serine protease inhibitor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.60.30 Alpha Beta 2-Layer Sandwich Wheat Germ Agglutinin (Isolectin 2); domain 1 Wheat Germ Agglutinin (Isolectin 2); domain 1 2leoA00
2N71A 1LR7A 1YTPA 1H0ZA 1SGNI 1TUSA 2ERWA 4HGUA 4SGBI 2BUSA 2GKVA 1LR9A 1HDLA 1KMAA 2SGPI 1TIHA 1Y1CA 2XRCA 3HH2C 1SGEI 1OYVI 1SGYI 1IY5A 3QTLD 1TURA 1CGII 2NU3I 2LEOA 4OVOA 2B0UC 2JYYA 2KCXA 1IY6A 1CE3A 1OMUA 3SGQI 3TJQA 1M8CA 2NU2I 1R0RI 3B4VC 2NU1I 1BMOA 1HJAI 3SEKC 2NU0I 1CSOI 2M5XA 1DS2I 1PPFI 1CHOI 2NU4I 1CT0I 1UVGA 2SGEI 1TBRR 1PCEA 1Y1BA 1AN1I 2ARPF 1DS3I 1FYBA 2SGFI 3OVOA 1MT1A 1SGPI 1HPTA 1SGRI 2GKTI 4GI3C 2GKRI 1LR8A 1CT2I 1CGJI 2KMRA 1BUSA 1SGQI 2WCYA 2N52A 1SGDI 2F3CI 1TBQR 1Z7KB 2SGDI 2N17A 1N13A 5JHWC 2QQDA 1TGSI 1NUBA 1UVFA 1PJUA 1UUCA 1CT4I 2KMQA 2KMPA 3SGBI 2JZMA 1IW4A 2KMOA 2JXDA 1OMTA 1YU6C 2OVOA 1M8BA 2V53A 2SGQI 5DAEA 2QQCA 1OVOA 2P6AC
chains in the Genus database with same CATH superfamily
2J87A 5HQ8A 2N71A 1WKXA 2JW6A 1LR7A 3CXLA 4B6DA 2QQ0A 2V1CA 1YTPA 5EX0A 1H0ZA 1KBFA 1SGNI 1V1IA 3PDNA 3TO6A 2ORVA 2LUYA 1TUSA 1ULMA 2ERWA 1WTJA 3R5DA 4HGUA 2CWFA 4MPIA 3FSYA 2UVOA 3QWPA 5HI7A 4SGBI 2BUSA 7WGAA 2GKVA 1LR9A 2A20A 1HDLA 1KMAA 2SGPI 3RU0A 2ENZA 1X74A 1TIHA 3R5BA 2ENNA 1Y1CA 2XRCA 1FY7A 3FC3A 2Y0MA 3D00A 3R5CA 2JA1A 1SGEI 1OYVI 1SGYI 3E2IA 3E59A 3HH2C 5CCLA 1IY5A 3QTLD 1MJAA 1TURA 1WGCA 3VDUA 1K7VA 1CGII 2NU3I 2LEOA 2QQEA 2B0UC 2JYYA 2KCXA 2OD1A 2PQ8A 2OU2A 4OVOA 3FSXA 1CE3A 1OMUA 3SGQI 3TJQA 1XBTA 2ODDA 3TOBA 1MJBA 4L9MA 1M8CA 5FUYA 2NU2I 1R0RI 3B4VC 1P9GA 1K7UA 1TOTA 1UHAA 2NU1I 1R79A 3VE5A 1BMOA 4A24A 1KBEA 2E5RA 3UGDA 2WVJA 4UXJA 1HJAI 1Z2IA 2L7XA 3SEKC 2NU0I 1CSOI 2J9RA 2M5XA 1DS2I 2WGCA 2N1AB 1ULKA 5E3QA 3OXLA 1PPFI 1WGTA 5FUWA 2E73A 1CHOI 1XX6A 2NU4I 3UEJA 1CT0I 1UVGA 2SGEI 2P6AC 1Q9BA 1IY6A 1TBRR 5J8FA 1PCEA 3OXGA 4DNCA 1Y1BA 1AN1I 1U5KA 1DS3I 2ARPF 5CCMA 1V1HA 1FYBA 2SGFI 3OVOA 1MT1A 2X52A 1SGPI 1HPTA 1VDDA 1PTRA 1SGRI 1FARA 2X3TA 2GKTI 2GVIA 2UZ3A 2GKRI 4GI3C 5FUVA 1HEVA 2W0TA 3KY9A 1LR8A 5J8CA 3OL0A 3TOAA 1PTQA 1W3SA 2ELIA 1CT2I 1CGJI 3MEKA 2KMRA 4E1PA 1XA6A 1BUSA 1SGQI 2DB6A 3R5AA 2WCYA 2N52A 5E3RA 3GOXA 1SGDI 2F3CI 1TBQR 3UEYA 2CWGA 4AMLA 1Z7KB 2L8EA 2N17A 2SGDI 1N13A 9WGAA 2DIPA 3VDPA 3UFFA 5E3PA 2V1CC 5JHWC 2K9HA 4FKDA 2VRWB 2QQDA 4WP4A 1S20A 1TBNA 1TGSI 2RIJA 5FUXA 1NUBA 2ROWA 1UVFA 1K7TA 1PJUA 1UUCA 3UGIA 2YUUA 1TBOA 1CT4I 1P9ZA 1W4RA 2KMPA 2JZMA 2KMQA 4UXIA 2ORWA 3SGBI 4JCVE 2RC4A 1MJ9A 2B8TA 2KMOA 2JXDA 3BJIA 2CWHA 1IW4A 2LB7A 1OMTA 1YU6C 1ULNA 2OVOA 1M8BA 2FNFX 2QPOA 2V53A 4E1RA 2CJSC 1FAQA 3TO9A 3UOEA 2SGQI 5EX3A 3QAHA 4UXHA 5DAEA 1NXUA 3OXFA 3UGLA 2YQPA 2QQCA 2DKVA 3TO7A 2GIVA 1OVOA 1RFHA 1Y8FA 2OZUA 1X4SA
chains in the Genus database with same CATH topology
2J87A 5HQ8A 2N71A 2JW6A 1LR7A 3CXLA 4B6DA 2QQ0A 1YTPA 5EX0A 1H0ZA 1KBFA 1SGNI 1V1IA 3PDNA 2ORVA 2LUYA 1TUSA 2ERWA 4HGUA 3QWPA 5HI7A 4SGBI 2BUSA 2GKVA 1LR9A 2A20A 1HDLA 1KMAA 2SGPI 3RU0A 2ENZA 1X74A 1TIHA 2ENNA 1Y1CA 2XRCA 3FC3A 3D00A 2JA1A 1SGEI 1OYVI 1SGYI 3E2IA 3E59A 3HH2C 5CCLA 1IY5A 3QTLD 1TURA 3VDUA 1CGII 2NU3I 2LEOA 2QQEA 2B0UC 2JYYA 2KCXA 2OD1A 4OVOA 1CE3A 1IY6A 1OMUA 3SGQI 3TJQA 1XBTA 2ODDA 4L9MA 1M8CA 5FUYA 2NU2I 1R0RI 3B4VC 1TOTA 2NU1I 1R79A 3VE5A 1BMOA 4A24A 1KBEA 2E5RA 3UGDA 2WVJA 4UXJA 1HJAI 2L7XA 3SEKC 2NU0I 1CSOI 2J9RA 2M5XA 1DS2I 2N1AB 3OXLA 1PPFI 5FUWA 2E73A 1CHOI 1XX6A 2NU4I 1CT0I 1UVGA 2SGEI 2P6AC 1TBRR 1PCEA 3OXGA 1Y1BA 1AN1I 1U5KA 1DS3I 2ARPF 5CCMA 1V1HA 1FYBA 2SGFI 3OVOA 1MT1A 1SGPI 1HPTA 1PTRA 1SGRI 1VDDA 1FARA 2GKTI 2GVIA 2UZ3A 2GKRI 4GI3C 5FUVA 2W0TA 3KY9A 1LR8A 3OL0A 1PTQA 1W3SA 2ELIA 1CT2I 1CGJI 3MEKA 2KMRA 4E1PA 1XA6A 1BUSA 1SGQI 2DB6A 2WCYA 2N52A 3GOXA 1SGDI 2F3CI 1TBQR 3UEYA 1Z7KB 2L8EA 2N17A 2SGDI 1N13A 2DIPA 3VDPA 3UFFA 2V1CC 5JHWC 2K9HA 4FKDA 2VRWB 2QQDA 5FUXA 1TGSI 1TBNA 1NUBA 2ROWA 1UVFA 1PJUA 1UUCA 3UGIA 2YUUA 1TBOA 1CT4I 1W4RA 2KMPA 2KMQA 2JZMA 4UXIA 3SGBI 2ORWA 3UEJA 4JCVE 3BJIA 3UGLA 2B8TA 2KMOA 2JXDA 1IW4A 1OMTA 1YU6C 2OVOA 1M8BA 2FNFX 2QPOA 2V53A 4E1RA 2CJSC 1FAQA 2SGQI 5EX3A 5DAEA 4UXHA 3OXFA 2YQPA 2QQCA 1OVOA 1RFHA 1Y8FA 2V1CA 1X4SA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2N71 A;  1LR7 A;  1YTP A;  1H0Z A;  1SGN I;  1TUS A;  2ERW A;  4HGU A;  4SGB I;  2BUS A;  2GKV A;  1LR9 A;  1HDL A;  1KMA A;  2SGP I;  1TIH A;  1Y1C A;  2XRC A;  3HH2 C;  1SGE I;  1OYV I;  1SGY I;  1IY5 A;  3QTL D;  1TUR A;  1CGI I;  2NU3 I;  2LEO A;  4OVO A;  2B0U C;  2JYY A;  2KCX A;  1IY6 A;  1CE3 A;  1OMU A;  3SGQ I;  3TJQ A;  1M8C A;  2NU2 I;  1R0R I;  3B4V C;  2NU1 I;  1BMO A;  1HJA I;  3SEK C;  2NU0 I;  1CSO I;  2M5X A;  1DS2 I;  1PPF I;  1CHO I;  2NU4 I;  1CT0 I;  1UVG A;  2SGE I;  1TBR R;  1PCE A;  1Y1B A;  1AN1 I;  2ARP F;  1DS3 I;  1FYB A;  2SGF I;  3OVO A;  1MT1 A;  1SGP I;  1HPT A;  1SGR I;  2GKT I;  4GI3 C;  2GKR I;  1LR8 A;  1CT2 I;  1CGJ I;  2KMR A;  1BUS A;  1SGQ I;  2WCY A;  2N52 A;  1SGD I;  2F3C I;  1TBQ R;  1Z7K B;  2SGD I;  2N17 A;  1N13 A;  5JHW C;  2QQD A;  1TGS I;  1NUB A;  1UVF A;  1PJU A;  1UUC A;  1CT4 I;  2KMQ A;  2KMP A;  3SGB I;  2JZM A;  1IW4 A;  2KMO A;  2JXD A;  1OMT A;  1YU6 C;  2OVO A;  1M8B A;  2V53 A;  2SGQ I;  5DAE A;  2QQC A;  1OVO A;  2P6A C; 
#chains in the Genus database with same CATH topology
 2J87 A;  5HQ8 A;  2N71 A;  1WKX A;  2JW6 A;  1LR7 A;  3CXL A;  4B6D A;  2QQ0 A;  2V1C A;  1YTP A;  5EX0 A;  1H0Z A;  1KBF A;  1SGN I;  1V1I A;  3PDN A;  3TO6 A;  2ORV A;  2LUY A;  1TUS A;  1ULM A;  2ERW A;  1WTJ A;  3R5D A;  4HGU A;  2CWF A;  4MPI A;  3FSY A;  2UVO A;  3QWP A;  5HI7 A;  4SGB I;  2BUS A;  7WGA A;  2GKV A;  1LR9 A;  2A20 A;  1HDL A;  1KMA A;  2SGP I;  3RU0 A;  2ENZ A;  1X74 A;  1TIH A;  3R5B A;  2ENN A;  1Y1C A;  2XRC A;  1FY7 A;  3FC3 A;  2Y0M A;  3D00 A;  3R5C A;  2JA1 A;  1SGE I;  1OYV I;  1SGY I;  3E2I A;  3E59 A;  3HH2 C;  5CCL A;  1IY5 A;  3QTL D;  1MJA A;  1TUR A;  1WGC A;  3VDU A;  1K7V A;  1CGI I;  2NU3 I;  2LEO A;  2QQE A;  2B0U C;  2JYY A;  2KCX A;  2OD1 A;  2PQ8 A;  2OU2 A;  4OVO A;  3FSX A;  1CE3 A;  1OMU A;  3SGQ I;  3TJQ A;  1XBT A;  2ODD A;  3TOB A;  1MJB A;  4L9M A;  1M8C A;  5FUY A;  2NU2 I;  1R0R I;  3B4V C;  1P9G A;  1K7U A;  1TOT A;  1UHA A;  2NU1 I;  1R79 A;  3VE5 A;  1BMO A;  4A24 A;  1KBE A;  2E5R A;  3UGD A;  2WVJ A;  4UXJ A;  1HJA I;  1Z2I A;  2L7X A;  3SEK C;  2NU0 I;  1CSO I;  2J9R A;  2M5X A;  1DS2 I;  2WGC A;  2N1A B;  1ULK A;  5E3Q A;  3OXL A;  1PPF I;  1WGT A;  5FUW A;  2E73 A;  1CHO I;  1XX6 A;  2NU4 I;  3UEJ A;  1CT0 I;  1UVG A;  2SGE I;  2P6A C;  1Q9B A;  1IY6 A;  1TBR R;  5J8F A;  1PCE A;  3OXG A;  4DNC A;  1Y1B A;  1AN1 I;  1U5K A;  1DS3 I;  2ARP F;  5CCM A;  1V1H A;  1FYB A;  2SGF I;  3OVO A;  1MT1 A;  2X52 A;  1SGP I;  1HPT A;  1VDD A;  1PTR A;  1SGR I;  1FAR A;  2X3T A;  2GKT I;  2GVI A;  2UZ3 A;  2GKR I;  4GI3 C;  5FUV A;  1HEV A;  2W0T A;  3KY9 A;  1LR8 A;  5J8C A;  3OL0 A;  3TOA A;  1PTQ A;  1W3S A;  2ELI A;  1CT2 I;  1CGJ I;  3MEK A;  2KMR A;  4E1P A;  1XA6 A;  1BUS A;  1SGQ I;  2DB6 A;  3R5A A;  2WCY A;  2N52 A;  5E3R A;  3GOX A;  1SGD I;  2F3C I;  1TBQ R;  3UEY A;  2CWG A;  4AML A;  1Z7K B;  2L8E A;  2N17 A;  2SGD I;  1N13 A;  9WGA A;  2DIP A;  3VDP A;  3UFF A;  5E3P A;  2V1C C;  5JHW C;  2K9H A;  4FKD A;  2VRW B;  2QQD A;  4WP4 A;  1S20 A;  1TBN A;  1TGS I;  2RIJ A;  5FUX A;  1NUB A;  2ROW A;  1UVF A;  1K7T A;  1PJU A;  1UUC A;  3UGI A;  2YUU A;  1TBO A;  1CT4 I;  1P9Z A;  1W4R A;  2KMP A;  2JZM A;  2KMQ A;  4UXI A;  2ORW A;  3SGB I;  4JCV E;  2RC4 A;  1MJ9 A;  2B8T A;  2KMO A;  2JXD A;  3BJI A;  2CWH A;  1IW4 A;  2LB7 A;  1OMT A;  1YU6 C;  1ULN A;  2OVO A;  1M8B A;  2FNF X;  2QPO A;  2V53 A;  4E1R A;  2CJS C;  1FAQ A;  3TO9 A;  3UOE A;  2SGQ I;  5EX3 A;  3QAH A;  4UXH A;  5DAE A;  1NXU A;  3OXF A;  3UGL A;  2YQP A;  2QQC A;  2DKV A;  3TO7 A;  2GIV A;  1OVO A;  1RFH A;  1Y8F A;  2OZU A;  1X4S A; 
#chains in the Genus database with same CATH homology
 2J87 A;  5HQ8 A;  2N71 A;  2JW6 A;  1LR7 A;  3CXL A;  4B6D A;  2QQ0 A;  1YTP A;  5EX0 A;  1H0Z A;  1KBF A;  1SGN I;  1V1I A;  3PDN A;  2ORV A;  2LUY A;  1TUS A;  2ERW A;  4HGU A;  3QWP A;  5HI7 A;  4SGB I;  2BUS A;  2GKV A;  1LR9 A;  2A20 A;  1HDL A;  1KMA A;  2SGP I;  3RU0 A;  2ENZ A;  1X74 A;  1TIH A;  2ENN A;  1Y1C A;  2XRC A;  3FC3 A;  3D00 A;  2JA1 A;  1SGE I;  1OYV I;  1SGY I;  3E2I A;  3E59 A;  3HH2 C;  5CCL A;  1IY5 A;  3QTL D;  1TUR A;  3VDU A;  1CGI I;  2NU3 I;  2LEO A;  2QQE A;  2B0U C;  2JYY A;  2KCX A;  2OD1 A;  4OVO A;  1CE3 A;  1IY6 A;  1OMU A;  3SGQ I;  3TJQ A;  1XBT A;  2ODD A;  4L9M A;  1M8C A;  5FUY A;  2NU2 I;  1R0R I;  3B4V C;  1TOT A;  2NU1 I;  1R79 A;  3VE5 A;  1BMO A;  4A24 A;  1KBE A;  2E5R A;  3UGD A;  2WVJ A;  4UXJ A;  1HJA I;  2L7X A;  3SEK C;  2NU0 I;  1CSO I;  2J9R A;  2M5X A;  1DS2 I;  2N1A B;  3OXL A;  1PPF I;  5FUW A;  2E73 A;  1CHO I;  1XX6 A;  2NU4 I;  1CT0 I;  1UVG A;  2SGE I;  2P6A C;  1TBR R;  1PCE A;  3OXG A;  1Y1B A;  1AN1 I;  1U5K A;  1DS3 I;  2ARP F;  5CCM A;  1V1H A;  1FYB A;  2SGF I;  3OVO A;  1MT1 A;  1SGP I;  1HPT A;  1PTR A;  1SGR I;  1VDD A;  1FAR A;  2GKT I;  2GVI A;  2UZ3 A;  2GKR I;  4GI3 C;  5FUV A;  2W0T A;  3KY9 A;  1LR8 A;  3OL0 A;  1PTQ A;  1W3S A;  2ELI A;  1CT2 I;  1CGJ I;  3MEK A;  2KMR A;  4E1P A;  1XA6 A;  1BUS A;  1SGQ I;  2DB6 A;  2WCY A;  2N52 A;  3GOX A;  1SGD I;  2F3C I;  1TBQ R;  3UEY A;  1Z7K B;  2L8E A;  2N17 A;  2SGD I;  1N13 A;  2DIP A;  3VDP A;  3UFF A;  2V1C C;  5JHW C;  2K9H A;  4FKD A;  2VRW B;  2QQD A;  5FUX A;  1TGS I;  1TBN A;  1NUB A;  2ROW A;  1UVF A;  1PJU A;  1UUC A;  3UGI A;  2YUU A;  1TBO A;  1CT4 I;  1W4R A;  2KMP A;  2KMQ A;  2JZM A;  4UXI A;  3SGB I;  2ORW A;  3UEJ A;  4JCV E;  3BJI A;  3UGL A;  2B8T A;  2KMO A;  2JXD A;  1IW4 A;  1OMT A;  1YU6 C;  2OVO A;  1M8B A;  2FNF X;  2QPO A;  2V53 A;  4E1R A;  2CJS C;  1FAQ A;  2SGQ I;  5EX3 A;  5DAE A;  4UXH A;  3OXF A;  2YQP A;  2QQC A;  1OVO A;  1RFH A;  1Y8F A;  2V1C A;  1X4S A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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