The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.
Total Genus |
62
|
sequence length |
288
|
structure length |
278
|
Chain Sequence |
GNCWLRQAKNGRCQVLYKTELSKEECCSTGRLSTSWTEEDVNDNTLFKWMIFNGGAPNCIPCKETCENVDCGPGKKCRMNKKNKPRCVCAPDCSNITWKGPVCGLDGKTYRNECALLKARCKEQPELEVQYQGRCKKTCRDVFCPGSSTCVVDQTNNAYCVTCNRICPEQYLCGNDGVTYSSACHLRKATCLLGRSIGLAYEGKCIKAKSCEDIQCTGGKKCLWDFKVGRGRCSLCDELCPEPVCASDNATYASECAMKEAACSSGVLLEVKHSGSCN
|
The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.
After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.
| molecule keywords |
Growth/differentiation factor 8
|
| publication title |
The structure of myostatin:follistatin 288: insights into receptor utilization and heparin binding
pubmed doi rcsb |
| source organism |
Mus musculus
|
| molecule tags |
Signaling protein/cytokine
|
| total genus |
62
|
| structure length |
278
|
| sequence length |
288
|
| chains with identical sequence |
D
|
| ec nomenclature | |
| pdb deposition date | 2009-05-14 |
| chain | Pfam Accession Code | Pfam Family Identifier | Pfam Description |
|---|---|---|---|
| C | PF07648 | Kazal_2 | Kazal-type serine protease inhibitor domain |
| C | PF09289 | FOLN | Follistatin/Osteonectin-like EGF domain |
Image from the rcsb pdb (www.rcsb.org)
cath code
| Class | Architecture | Topology | Homology | Domain |
|---|---|---|---|---|---|
| Alpha Beta | 2-Layer Sandwich | Wheat Germ Agglutinin (Isolectin 2); domain 1 | Wheat Germ Agglutinin (Isolectin 2); domain 1 | ||
| Alpha Beta | 2-Layer Sandwich | Wheat Germ Agglutinin (Isolectin 2); domain 1 | Wheat Germ Agglutinin (Isolectin 2); domain 1 | ||
| Alpha Beta | 2-Layer Sandwich | Wheat Germ Agglutinin (Isolectin 2); domain 1 | Wheat Germ Agglutinin (Isolectin 2); domain 1 | ||
| Alpha Beta | Alpha-Beta Complex | Extracellular Matrix Fibrillin | TGF-beta binding (TB) domain |
#chains in the Genus database with same CATH superfamily 2SGQ I; 1Y1B A; 1SGN I; 2ARP F; 1OYV I; 2W86 A; 1PJU A; 1YTP A; 3SGQ I; 2P6A C; 1IW4 A; 4SGB I; 2N17 A; 1UVG A; 1UUC A; 2NU3 I; 1BMO A; 1CGJ I; 1TBR R; 1SGD I; 2KMQ A; 1APJ A; 2NU1 I; 1UVF A; 2ERW A; 1IY6 A; 1LR8 A; 2KMO A; 1H0Z A; 1HPT A; 2B0U C; 2SGP I; 1M8C A; 2V53 A; 1KMA A; 2XRC A; 3SGB I; 2N71 A; 1SGP I; 2GKR I; 1NUB A; 1OMU A; 1SGY I; 1CE3 A; 1HDL A; 2M5X A; 2SGF I; 1SGR I; 2NU4 I; 1KSQ A; 1N13 A; 1TGS I; 3OVO A; 4HGU A; 1SGE I; 2SGE I; 2QQD A; 2KCX A; 1TUS A; 1FYB A; 4GI3 C; 1LR7 A; 1CGI I; 4OVO A; 2NU0 I; 2GKT I; 2NU2 I; 1TBQ R; 2LEO A; 2KMR A; 1PCE A; 1M8B A; 2F3C I; 1Y1C A; 2OVO A; 2JZM A; 1UZP A; 1AN1 I; 1DS3 I; 1BUS A; 2JXD A; 5DAE A; 1IY5 A; 1OVO A; 2GKV A; 1CHO I; 1CSO I; 2N52 A; 1Z7K B; 1CT2 I; 1TUR A; 1DS2 I; 1TIH A; 1LR9 A; 2WCY A; 1YU6 C; 3HH2 C; 1R0R I; 2BUS A; 1CT4 I; 1UZK A; 2QQC A; 1OMT A; 1CT0 I; 2SGD I; 2JYY A; 1SGQ I; 3TJQ A; 3QTL D; 3B4V C; 1HJA I; 3SEK C; 1PPF I; 5JHW C; 1UZQ A; 1UZJ A; 1MT1 A; 2KMP A; #chains in the Genus database with same CATH topology 5J8F A; 1MJB A; 4MPI A; 2W0T A; 2X52 A; 2SGQ I; 1Y1B A; 1FY7 A; 1SGN I; 2L7X A; 2ARP F; 2ENZ A; 5FUY A; 1OYV I; 5FUV A; 1UZJ A; 2W86 A; 1PJU A; 1YTP A; 3SGQ I; 2P6A C; 5HI7 A; 4B6D A; 2YQP A; 3D00 A; 1IW4 A; 1ULK A; 1XX6 A; 3OL0 A; 1XA6 A; 4SGB I; 5FUW A; 3UOE A; 1WGC A; 2ORW A; 2N17 A; 5FUX A; 1UVG A; 1UUC A; 2ENN A; 5EX0 A; 2NU3 I; 2UZ3 A; 5HQ8 A; 1BMO A; 4UXI A; 2PQ8 A; 1CGJ I; 2OU2 A; 1TOT A; 1TBR R; 5E3Q A; 1KBE A; 1SGD I; 2GIV A; 2KMQ A; 1APJ A; 2NU1 I; 1UVF A; 3OXG A; 2ERW A; 1IY6 A; 4L9M A; 1LR8 A; 2KMO A; 3R5B A; 2FNF X; 2OD1 A; 1H0Z A; 5EX3 A; 1WGT A; 1HPT A; 5CCL A; 1KBF A; 1FAR A; 2B0U C; 2SGP I; 1M8C A; 2UVO A; 2V53 A; 1K7U A; 2XRC A; 1HEV A; 1KMA A; 3UGL A; 3SGB I; 4JCV E; 2CWF A; 1TBO A; 1Z2I A; 2N71 A; 5CCM A; 2Y0M A; 1SGP I; 3KY9 A; 2GKR I; 3MEK A; 2N1A B; 1ULN A; 1NUB A; 1OMU A; 1R79 A; 1SGY I; 1X4S A; 3GOX A; 3TOB A; 1Y8F A; 1CE3 A; 2YUU A; 3CXL A; 1HDL A; 2M5X A; 2CJS C; 2SGF I; 1SGR I; 2V1C A; 1VDD A; 2NU4 I; 2E5R A; 2J87 A; 1KSQ A; 1WKX A; 1UHA A; 1W4R A; 1V1H A; 1N13 A; 1WTJ A; 1TGS I; 3OVO A; 3TO6 A; 1S20 A; 2LUY A; 3FC3 A; 4HGU A; 1SGE I; 2SGE I; 2GVI A; 2QQD A; 4AML A; 1K7V A; 2KCX A; 2JA1 A; 3VE5 A; 1TUS A; 4DNC A; 1W3S A; 1FYB A; 2QPO A; 4GI3 C; 3UEY A; 4UXJ A; 2ODD A; 1LR7 A; 2LB7 A; 2ROW A; 3BJI A; 3FSY A; 1CGI I; 2JW6 A; 3TO7 A; 1MJ9 A; 2OZU A; 3R5D A; 2X3T A; 4OVO A; 1TBN A; 4UXH A; 3R5C A; 2NU0 I; 2GKT I; 2NU2 I; 1TBQ R; 2LEO A; 1ULM A; 2KMR A; 4E1P A; 3OXF A; 1PCE A; 1PTQ A; 1RFH A; 1XBT A; 4WP4 A; 1M8B A; 2F3C I; 1Y1C A; 2RIJ A; 3E59 A; 3UEJ A; 2OVO A; 3OXL A; 3R5A A; 1Q9B A; 5E3P A; 2JZM A; 3E2I A; 1UZP A; 3QAH A; 1AN1 I; 2DIP A; 2J9R A; 1DS3 I; 1P9G A; 2B8T A; 1BUS A; 2JXD A; 5DAE A; 1IY5 A; 1OVO A; 2CWH A; 1CHO I; 2GKV A; 2CWG A; 5E3R A; 1V1I A; 3RU0 A; 1CSO I; 3UFF A; 2QQE A; 2N52 A; 3PDN A; 3UGI A; 3VDU A; 2QQ0 A; 5J8C A; 1Z7K B; 1CT2 I; 1TUR A; 1DS2 I; 2WGC A; 3UGD A; 1TIH A; 4FKD A; 1LR9 A; 4E1R A; 2K9H A; 2DKV A; 1K7T A; 2WCY A; 2A20 A; 3TOA A; 1X74 A; 2RC4 A; 1YU6 C; 3HH2 C; 7WGA A; 4A24 A; 1P9Z A; 2ELI A; 2E73 A; 3TO9 A; 1R0R I; 2BUS A; 1CT4 I; 1UZK A; 2QQC A; 1OMT A; 3VDP A; 1MJA A; 1CT0 I; 2ORV A; 2SGD I; 1NXU A; 1PTR A; 2WVJ A; 2JYY A; 1SGQ I; 3TJQ A; 2VRW B; 2L8E A; 2V1C C; 1HJA I; 3B4V C; 3QTL D; 3QWP A; 3SEK C; 1PPF I; 5JHW C; 1FAQ A; 2DB6 A; 1U5K A; 1UZQ A; 9WGA A; 1MT1 A; 3FSX A; 2KMP A; #chains in the Genus database with same CATH homology 2W0T A; 2SGQ I; 1Y1B A; 2L7X A; 1SGN I; 5FUY A; 2ARP F; 2ENZ A; 1OYV I; 5FUV A; 2W86 A; 1PJU A; 1YTP A; 3SGQ I; 2P6A C; 5HI7 A; 4B6D A; 2YQP A; 3D00 A; 1IW4 A; 1XX6 A; 3OL0 A; 5FUW A; 1XA6 A; 4SGB I; 2ORW A; 2N17 A; 5FUX A; 1UVG A; 1UUC A; 2ENN A; 5EX0 A; 2NU3 I; 2UZ3 A; 5HQ8 A; 1BMO A; 4UXI A; 1CGJ I; 1TOT A; 1TBR R; 1KBE A; 1SGD I; 2KMQ A; 1APJ A; 2NU1 I; 1UVF A; 3OXG A; 2ERW A; 1IY6 A; 4L9M A; 1LR8 A; 2KMO A; 2FNF X; 2OD1 A; 1H0Z A; 5EX3 A; 5CCL A; 1HPT A; 1KBF A; 1FAR A; 2B0U C; 2SGP I; 1M8C A; 2V53 A; 1KMA A; 2XRC A; 3UGL A; 3SGB I; 4JCV E; 1TBO A; 5CCM A; 2N71 A; 1SGP I; 3KY9 A; 2GKR I; 3MEK A; 2N1A B; 1NUB A; 1OMU A; 1R79 A; 1SGY I; 1X4S A; 3GOX A; 1Y8F A; 1CE3 A; 2YUU A; 3CXL A; 1HDL A; 2M5X A; 2CJS C; 2SGF I; 1SGR I; 2V1C A; 1VDD A; 2NU4 I; 2E5R A; 2J87 A; 1KSQ A; 1V1H A; 1N13 A; 1W4R A; 1TGS I; 3OVO A; 3FC3 A; 2LUY A; 4HGU A; 1SGE I; 2SGE I; 2GVI A; 2QQD A; 2KCX A; 2JA1 A; 3VE5 A; 1TUS A; 1W3S A; 1FYB A; 2QPO A; 4GI3 C; 3UEY A; 4UXJ A; 2ODD A; 1LR7 A; 2ROW A; 3BJI A; 1CGI I; 2JW6 A; 4OVO A; 1TBN A; 4UXH A; 2NU0 I; 2GKT I; 2NU2 I; 1TBQ R; 2LEO A; 4E1P A; 2KMR A; 3OXF A; 1PCE A; 1PTQ A; 1RFH A; 1XBT A; 1M8B A; 2F3C I; 1Y1C A; 3E59 A; 3UEJ A; 2OVO A; 3OXL A; 2JZM A; 3E2I A; 1UZP A; 1AN1 I; 2DIP A; 2J9R A; 1DS3 I; 2B8T A; 1BUS A; 2JXD A; 5DAE A; 1IY5 A; 1OVO A; 2GKV A; 1CHO I; 3UGI A; 3RU0 A; 1V1I A; 3VDU A; 1CSO I; 3UFF A; 2QQE A; 2N52 A; 3PDN A; 1FAQ A; 2QQ0 A; 1Z7K B; 1CT2 I; 1TUR A; 1DS2 I; 3UGD A; 1TIH A; 4FKD A; 1LR9 A; 4E1R A; 2K9H A; 2WCY A; 2A20 A; 1X74 A; 1YU6 C; 3HH2 C; 4A24 A; 2ELI A; 2E73 A; 1R0R I; 2BUS A; 1CT4 I; 1UZK A; 2QQC A; 1OMT A; 3VDP A; 1CT0 I; 2ORV A; 2SGD I; 1PTR A; 2WVJ A; 2JYY A; 1SGQ I; 3TJQ A; 2VRW B; 2L8E A; 2V1C C; 1HJA I; 3B4V C; 3QTL D; 3QWP A; 3SEK C; 1PPF I; 5JHW C; 2DB6 A; 1U5K A; 1UZQ A; 1UZJ A; 1MT1 A; 2KMP A;
#similar chains in the Genus database (?% sequence similarity) ...loading similar chains, please wait... #similar chains, but unknotted ...loading similar chains, please wait... #similar chains in the pdb database (?% sequence similarity) ...loading similar chains, please wait...
