1AN1I

Leech-derived tryptase inhibitor/trypsin complex
Total Genus 9
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
9
sequence length
40
structure length
40
Chain Sequence
KVCACPKILKPVCGSDGRTYANSCIARCNGVSIKSEGSCP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords TRYPSIN
publication title Structure of the complex of leech-derived tryptase inhibitor (LDTI) with trypsin and modeling of the LDTI-tryptase system.
pubmed doi rcsb
source organism Sus scrofa
molecule tags Complex (serine protease/inhibitor)
total genus 9
structure length 40
sequence length 40
ec nomenclature
pdb deposition date 1997-06-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
I PF00050 Kazal_1 Kazal-type serine protease inhibitor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.60.30 Alpha Beta 2-Layer Sandwich Wheat Germ Agglutinin (Isolectin 2); domain 1 Wheat Germ Agglutinin (Isolectin 2); domain 1 1an1I00
2KMQA 1UVGA 2M5XA 1CHOI 1IY6A 2LEOA 1Z7KB 1BUSA 2SGFI 5JHWC 3TJQA 2GKVA 1LR8A 2GKTI 1H0ZA 2JXDA 1CE3A 2SGQI 1DS3I 1TURA 1SGEI 1OVOA 1PCEA 1HJAI 1NUBA 2GKRI 2P6AC 1TIHA 2ARPF 1OMTA 1Y1BA 1IW4A 2NU3I 2NU2I 2N17A 3QTLD 3HH2C 1LR7A 1OMUA 1TUSA 1CT0I 1PPFI 1Y1CA 2ERWA 2XRCA 4GI3C 1YTPA 1CGJI 1SGNI 2JYYA 3SEKC 2NU1I 2JZMA 2V53A 1CSOI 4SGBI 1TBRR 1AN1I 2OVOA 1SGYI 3SGBI 4OVOA 2QQDA 2NU0I 1OYVI 1HDLA 1CT4I 1M8CA 2WCYA 1TGSI 1MT1A 1CGII 1LR9A 2F3CI 1SGQI 2SGPI 3OVOA 3B4VC 1SGDI 1R0RI 1UUCA 2KCXA 2BUSA 1FYBA 1PJUA 2KMRA 1HPTA 3SGQI 2KMOA 2N52A 1N13A 1TBQR 1BMOA 2SGEI 4HGUA 1M8BA 1YU6C 2B0UC 1CT2I 5DAEA 1UVFA 1SGPI 2NU4I 2QQCA 2N71A 2SGDI 1IY5A 1DS2I 1SGRI 1KMAA 2KMPA
chains in the Genus database with same CATH superfamily
3BJIA 1WKXA 5CCMA 1MJ9A 2KMQA 1UVGA 3OL0A 2M5XA 1CHOI 1IY6A 2OD1A 1RFHA 2LEOA 1V1HA 1Z7KB 3FSXA 2JW6A 1HEVA 1WGCA 1BUSA 2SGFI 3E59A 3TJQA 5JHWC 2GKVA 4UXIA 3OXLA 1LR8A 2CJSC 3UEYA 2CWGA 1VDDA 3UGDA 4L9MA 2GKTI 4WP4A 1H0ZA 2JXDA 3FSYA 2W0TA 1CE3A 2SGQI 1UHAA 1DS3I 1WTJA 1PTRA 3R5DA 1TBNA 5J8CA 9WGAA 2WGCA 1TURA 1SGEI 1MJBA 2K9HA 2ODDA 1TOTA 3CXLA 2QPOA 1OVOA 1PCEA 2LB7A 1FARA 4E1RA 2ORVA 1HJAI 2UVOA 1NUBA 2GKRI 2P6AC 2WVJA 5CCLA 3VDPA 1TIHA 2ARPF 5FUYA 1OMTA 1S20A 1Y1BA 1IW4A 1ULMA 1W3SA 2NU3I 3R5BA 3TOBA 2NU2I 2N17A 3QTLD 1NXUA 3HH2C 1XBTA 1LR7A 3VDUA 1MJAA 1OMUA 1TUSA 1XA6A 2B8TA 2DIPA 1CT0I 3OXGA 1PPFI 3QAHA 1Y1CA 4AMLA 3R5CA 3D00A 4FKDA 3TOAA 2YQPA 1W4RA 2ERWA 2JA1A 2XRCA 4GI3C 1YTPA 2QQEA 1CGJI 1SGNI 2V1CC 2ENZA 2JYYA 2OU2A 2UZ3A 2NU1I 2L8EA 3SEKC 1X4SA 2JZMA 2VRWB 2V53A 1CSOI 4SGBI 3TO9A 4A24A 5E3RA 1TBRR 1AN1I 2J9RA 2LUYA 2OVOA 2RIJA 3UGIA 1SGYI 1FAQA 3SGBI 4UXHA 4OVOA 3VE5A 5E3QA 2QQDA 3UFFA 2FNFX 1V1IA 2DKVA 2V1CA 2NU0I 1OYVI 1HDLA 2YUUA 1CT4I 1TBOA 1FY7A 2CWFA 2ORWA 4DNCA 3RU0A 3TO7A 1M8CA 2CWHA 2GVIA 2WCYA 5EX3A 1TGSI 1MT1A 2J87A 1CGII 4B6DA 1U5KA 1XX6A 1P9GA 1LR9A 2F3CI 1SGQI 2N1AB 2PQ8A 1R79A 2SGPI 3OVOA 2Y0MA 3B4VC 1SGDI 1KBEA 1K7VA 2QQ0A 2X52A 5FUXA 3TO6A 1R0RI 2ELIA 1UUCA 2KCXA 3OXFA 2X3TA 5HQ8A 1WGTA 1PTQA 2BUSA 2ROWA 1FYBA 1PJUA 3MEKA 3R5AA 2KMRA 7WGAA 1HPTA 2L7XA 5FUVA 3KY9A 3SGQI 2DB6A 2GIVA 3UOEA 2KMOA 2N52A 1N13A 1TBQR 2OZUA 1BMOA 5E3PA 1ULKA 2SGEI 2A20A 4HGUA 3PDNA 1K7UA 1M8BA 2ENNA 2RC4A 4E1PA 3GOXA 1X74A 3UEJA 1Z2IA 2E5RA 4UXJA 3UGLA 1ULNA 1YU6C 2B0UC 1CT2I 5DAEA 3FC3A 1Q9BA 1UVFA 1SGPI 2E73A 3E2IA 5HI7A 1P9ZA 4MPIA 5J8FA 2NU4I 2QQCA 2N71A 4JCVE 2SGDI 5FUWA 1IY5A 1DS2I 1SGRI 1K7TA 5EX0A 1KBFA 1KMAA 2KMPA 3QWPA 1Y8FA
chains in the Genus database with same CATH topology
3BJIA 5CCMA 2KMQA 1UVGA 3OL0A 2M5XA 1CHOI 1IY6A 2OD1A 1RFHA 2LEOA 1V1HA 1Z7KB 2JW6A 1BUSA 2SGFI 3E59A 3TJQA 5JHWC 2GKVA 4UXIA 3OXLA 1LR8A 2CJSC 3UEYA 1VDDA 3UGDA 4L9MA 2GKTI 1H0ZA 2JXDA 2W0TA 1CE3A 2SGQI 1DS3I 1PTRA 1TBNA 1TURA 1SGEI 2K9HA 2ODDA 1TOTA 3CXLA 2QPOA 1OVOA 1PCEA 1FARA 4E1RA 2ORVA 1HJAI 1NUBA 2GKRI 2P6AC 2WVJA 5CCLA 3VDPA 1TIHA 2ARPF 5FUYA 1OMTA 1Y1BA 1IW4A 1W3SA 2NU3I 2NU2I 2N17A 3QTLD 3HH2C 1XBTA 1LR7A 3VDUA 1OMUA 2DIPA 1TUSA 1XA6A 2B8TA 3OXGA 1CT0I 1PPFI 1Y1CA 3D00A 4FKDA 2YQPA 1W4RA 2ERWA 2JA1A 2XRCA 4GI3C 1YTPA 2QQEA 1CGJI 1SGNI 2V1CC 2ENZA 2JYYA 3SEKC 2UZ3A 2NU1I 2L8EA 1X4SA 2JZMA 2VRWB 2V53A 1CSOI 4SGBI 4A24A 1TBRR 1AN1I 2J9RA 2LUYA 2OVOA 3UGIA 1SGYI 1FAQA 3SGBI 4UXHA 4OVOA 3VE5A 2QQDA 3UFFA 2FNFX 1V1IA 2V1CA 2NU0I 1OYVI 1HDLA 2YUUA 1CT4I 1TBOA 2ORWA 3RU0A 1M8CA 2GVIA 2WCYA 5EX3A 1TGSI 1MT1A 2J87A 1CGII 4B6DA 1U5KA 1XX6A 1LR9A 2F3CI 1SGQI 2N1AB 1R79A 2SGPI 3OVOA 3B4VC 1SGDI 1KBEA 2QQ0A 5FUXA 1R0RI 2ELIA 1UUCA 2KCXA 3OXFA 5HQ8A 1PTQA 2BUSA 2ROWA 1FYBA 1PJUA 3MEKA 2KMRA 1HPTA 2L7XA 5FUVA 3KY9A 3SGQI 2DB6A 2KMOA 2N52A 1N13A 1TBQR 1BMOA 2SGEI 2A20A 4HGUA 3PDNA 1M8BA 2ENNA 4E1PA 3GOXA 1X74A 3UEJA 2E5RA 4UXJA 3UGLA 1YU6C 2B0UC 1CT2I 5DAEA 3FC3A 1UVFA 1SGPI 2E73A 3E2IA 5HI7A 2NU4I 2QQCA 2N71A 4JCVE 2SGDI 5FUWA 1IY5A 1DS2I 1SGRI 5EX0A 1KBFA 1KMAA 2KMPA 3QWPA 1Y8FA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2KMQ A;  1UVG A;  2M5X A;  1CHO I;  1IY6 A;  2LEO A;  1Z7K B;  1BUS A;  2SGF I;  5JHW C;  3TJQ A;  2GKV A;  1LR8 A;  2GKT I;  1H0Z A;  2JXD A;  1CE3 A;  2SGQ I;  1DS3 I;  1TUR A;  1SGE I;  1OVO A;  1PCE A;  1HJA I;  1NUB A;  2GKR I;  2P6A C;  1TIH A;  2ARP F;  1OMT A;  1Y1B A;  1IW4 A;  2NU3 I;  2NU2 I;  2N17 A;  3QTL D;  3HH2 C;  1LR7 A;  1OMU A;  1TUS A;  1CT0 I;  1PPF I;  1Y1C A;  2ERW A;  2XRC A;  4GI3 C;  1YTP A;  1CGJ I;  1SGN I;  2JYY A;  3SEK C;  2NU1 I;  2JZM A;  2V53 A;  1CSO I;  4SGB I;  1TBR R;  1AN1 I;  2OVO A;  1SGY I;  3SGB I;  4OVO A;  2QQD A;  2NU0 I;  1OYV I;  1HDL A;  1CT4 I;  1M8C A;  2WCY A;  1TGS I;  1MT1 A;  1CGI I;  1LR9 A;  2F3C I;  1SGQ I;  2SGP I;  3OVO A;  3B4V C;  1SGD I;  1R0R I;  1UUC A;  2KCX A;  2BUS A;  1FYB A;  1PJU A;  2KMR A;  1HPT A;  3SGQ I;  2KMO A;  2N52 A;  1N13 A;  1TBQ R;  1BMO A;  2SGE I;  4HGU A;  1M8B A;  1YU6 C;  2B0U C;  1CT2 I;  5DAE A;  1UVF A;  1SGP I;  2NU4 I;  2QQC A;  2N71 A;  2SGD I;  1IY5 A;  1DS2 I;  1SGR I;  1KMA A;  2KMP A; 
#chains in the Genus database with same CATH topology
 3BJI A;  1WKX A;  5CCM A;  1MJ9 A;  2KMQ A;  1UVG A;  3OL0 A;  2M5X A;  1CHO I;  1IY6 A;  2OD1 A;  1RFH A;  2LEO A;  1V1H A;  1Z7K B;  3FSX A;  2JW6 A;  1HEV A;  1WGC A;  1BUS A;  2SGF I;  3E59 A;  3TJQ A;  5JHW C;  2GKV A;  4UXI A;  3OXL A;  1LR8 A;  2CJS C;  3UEY A;  2CWG A;  1VDD A;  3UGD A;  4L9M A;  2GKT I;  4WP4 A;  1H0Z A;  2JXD A;  3FSY A;  2W0T A;  1CE3 A;  2SGQ I;  1UHA A;  1DS3 I;  1WTJ A;  1PTR A;  3R5D A;  1TBN A;  5J8C A;  9WGA A;  2WGC A;  1TUR A;  1SGE I;  1MJB A;  2K9H A;  2ODD A;  1TOT A;  3CXL A;  2QPO A;  1OVO A;  1PCE A;  2LB7 A;  1FAR A;  4E1R A;  2ORV A;  1HJA I;  2UVO A;  1NUB A;  2GKR I;  2P6A C;  2WVJ A;  5CCL A;  3VDP A;  1TIH A;  2ARP F;  5FUY A;  1OMT A;  1S20 A;  1Y1B A;  1IW4 A;  1ULM A;  1W3S A;  2NU3 I;  3R5B A;  3TOB A;  2NU2 I;  2N17 A;  3QTL D;  1NXU A;  3HH2 C;  1XBT A;  1LR7 A;  3VDU A;  1MJA A;  1OMU A;  1TUS A;  1XA6 A;  2B8T A;  2DIP A;  1CT0 I;  3OXG A;  1PPF I;  3QAH A;  1Y1C A;  4AML A;  3R5C A;  3D00 A;  4FKD A;  3TOA A;  2YQP A;  1W4R A;  2ERW A;  2JA1 A;  2XRC A;  4GI3 C;  1YTP A;  2QQE A;  1CGJ I;  1SGN I;  2V1C C;  2ENZ A;  2JYY A;  2OU2 A;  2UZ3 A;  2NU1 I;  2L8E A;  3SEK C;  1X4S A;  2JZM A;  2VRW B;  2V53 A;  1CSO I;  4SGB I;  3TO9 A;  4A24 A;  5E3R A;  1TBR R;  1AN1 I;  2J9R A;  2LUY A;  2OVO A;  2RIJ A;  3UGI A;  1SGY I;  1FAQ A;  3SGB I;  4UXH A;  4OVO A;  3VE5 A;  5E3Q A;  2QQD A;  3UFF A;  2FNF X;  1V1I A;  2DKV A;  2V1C A;  2NU0 I;  1OYV I;  1HDL A;  2YUU A;  1CT4 I;  1TBO A;  1FY7 A;  2CWF A;  2ORW A;  4DNC A;  3RU0 A;  3TO7 A;  1M8C A;  2CWH A;  2GVI A;  2WCY A;  5EX3 A;  1TGS I;  1MT1 A;  2J87 A;  1CGI I;  4B6D A;  1U5K A;  1XX6 A;  1P9G A;  1LR9 A;  2F3C I;  1SGQ I;  2N1A B;  2PQ8 A;  1R79 A;  2SGP I;  3OVO A;  2Y0M A;  3B4V C;  1SGD I;  1KBE A;  1K7V A;  2QQ0 A;  2X52 A;  5FUX A;  3TO6 A;  1R0R I;  2ELI A;  1UUC A;  2KCX A;  3OXF A;  2X3T A;  5HQ8 A;  1WGT A;  1PTQ A;  2BUS A;  2ROW A;  1FYB A;  1PJU A;  3MEK A;  3R5A A;  2KMR A;  7WGA A;  1HPT A;  2L7X A;  5FUV A;  3KY9 A;  3SGQ I;  2DB6 A;  2GIV A;  3UOE A;  2KMO A;  2N52 A;  1N13 A;  1TBQ R;  2OZU A;  1BMO A;  5E3P A;  1ULK A;  2SGE I;  2A20 A;  4HGU A;  3PDN A;  1K7U A;  1M8B A;  2ENN A;  2RC4 A;  4E1P A;  3GOX A;  1X74 A;  3UEJ A;  1Z2I A;  2E5R A;  4UXJ A;  3UGL A;  1ULN A;  1YU6 C;  2B0U C;  1CT2 I;  5DAE A;  3FC3 A;  1Q9B A;  1UVF A;  1SGP I;  2E73 A;  3E2I A;  5HI7 A;  1P9Z A;  4MPI A;  5J8F A;  2NU4 I;  2QQC A;  2N71 A;  4JCV E;  2SGD I;  5FUW A;  1IY5 A;  1DS2 I;  1SGR I;  1K7T A;  5EX0 A;  1KBF A;  1KMA A;  2KMP A;  3QWP A;  1Y8F A; 
#chains in the Genus database with same CATH homology
 3BJI A;  5CCM A;  2KMQ A;  1UVG A;  3OL0 A;  2M5X A;  1CHO I;  1IY6 A;  2OD1 A;  1RFH A;  2LEO A;  1V1H A;  1Z7K B;  2JW6 A;  1BUS A;  2SGF I;  3E59 A;  3TJQ A;  5JHW C;  2GKV A;  4UXI A;  3OXL A;  1LR8 A;  2CJS C;  3UEY A;  1VDD A;  3UGD A;  4L9M A;  2GKT I;  1H0Z A;  2JXD A;  2W0T A;  1CE3 A;  2SGQ I;  1DS3 I;  1PTR A;  1TBN A;  1TUR A;  1SGE I;  2K9H A;  2ODD A;  1TOT A;  3CXL A;  2QPO A;  1OVO A;  1PCE A;  1FAR A;  4E1R A;  2ORV A;  1HJA I;  1NUB A;  2GKR I;  2P6A C;  2WVJ A;  5CCL A;  3VDP A;  1TIH A;  2ARP F;  5FUY A;  1OMT A;  1Y1B A;  1IW4 A;  1W3S A;  2NU3 I;  2NU2 I;  2N17 A;  3QTL D;  3HH2 C;  1XBT A;  1LR7 A;  3VDU A;  1OMU A;  2DIP A;  1TUS A;  1XA6 A;  2B8T A;  3OXG A;  1CT0 I;  1PPF I;  1Y1C A;  3D00 A;  4FKD A;  2YQP A;  1W4R A;  2ERW A;  2JA1 A;  2XRC A;  4GI3 C;  1YTP A;  2QQE A;  1CGJ I;  1SGN I;  2V1C C;  2ENZ A;  2JYY A;  3SEK C;  2UZ3 A;  2NU1 I;  2L8E A;  1X4S A;  2JZM A;  2VRW B;  2V53 A;  1CSO I;  4SGB I;  4A24 A;  1TBR R;  1AN1 I;  2J9R A;  2LUY A;  2OVO A;  3UGI A;  1SGY I;  1FAQ A;  3SGB I;  4UXH A;  4OVO A;  3VE5 A;  2QQD A;  3UFF A;  2FNF X;  1V1I A;  2V1C A;  2NU0 I;  1OYV I;  1HDL A;  2YUU A;  1CT4 I;  1TBO A;  2ORW A;  3RU0 A;  1M8C A;  2GVI A;  2WCY A;  5EX3 A;  1TGS I;  1MT1 A;  2J87 A;  1CGI I;  4B6D A;  1U5K A;  1XX6 A;  1LR9 A;  2F3C I;  1SGQ I;  2N1A B;  1R79 A;  2SGP I;  3OVO A;  3B4V C;  1SGD I;  1KBE A;  2QQ0 A;  5FUX A;  1R0R I;  2ELI A;  1UUC A;  2KCX A;  3OXF A;  5HQ8 A;  1PTQ A;  2BUS A;  2ROW A;  1FYB A;  1PJU A;  3MEK A;  2KMR A;  1HPT A;  2L7X A;  5FUV A;  3KY9 A;  3SGQ I;  2DB6 A;  2KMO A;  2N52 A;  1N13 A;  1TBQ R;  1BMO A;  2SGE I;  2A20 A;  4HGU A;  3PDN A;  1M8B A;  2ENN A;  4E1P A;  3GOX A;  1X74 A;  3UEJ A;  2E5R A;  4UXJ A;  3UGL A;  1YU6 C;  2B0U C;  1CT2 I;  5DAE A;  3FC3 A;  1UVF A;  1SGP I;  2E73 A;  3E2I A;  5HI7 A;  2NU4 I;  2QQC A;  2N71 A;  4JCV E;  2SGD I;  5FUW A;  1IY5 A;  1DS2 I;  1SGR I;  5EX0 A;  1KBF A;  1KMA A;  2KMP A;  3QWP A;  1Y8F A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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