1AN1I

Leech-derived tryptase inhibitor/trypsin complex
Total Genus 9
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
9
sequence length
40
structure length
40
Chain Sequence
KVCACPKILKPVCGSDGRTYANSCIARCNGVSIKSEGSCP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Complex (serine protease/inhibitor)
molecule keywords TRYPSIN
publication title Structure of the complex of leech-derived tryptase inhibitor (LDTI) with trypsin and modeling of the LDTI-tryptase system.
pubmed doi rcsb
source organism Sus scrofa
total genus 9
structure length 40
sequence length 40
ec nomenclature
pdb deposition date 1997-06-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
I PF00050 Kazal_1 Kazal-type serine protease inhibitor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.60.30 Alpha Beta 2-Layer Sandwich Wheat Germ Agglutinin (Isolectin 2); domain 1 Wheat Germ Agglutinin (Isolectin 2); domain 1 1an1I00
1UVGA 1CT2I 2KMRA 1FYBA 2NU0I 1CSOI 1TBQR 4SGBI 2OVOA 1M8BA 1AN1I 5JHWC 1YTPA 1N13A 3SEKC 2KMOA 2ARPF 1SGPI 2NU4I 5DAEA 1NUBA 1UVFA 2JZMA 1HJAI 1DS2I 1PJUA 2KCXA 1OVOA 3QTLD 2SGFI 1IY6A 1IY5A 1H0ZA 3OVOA 2QQCA 1M8CA 1IW4A 1TIHA 1UUCA 2QQDA 1LR7A 2N71A 1BUSA 1KMAA 2SGDI 2GKVA 2JXDA 3HH2C 1HPTA 1CT4I 2P6AC 1SGDI 1CHOI 2ERWA 1Y1BA 1Y1CA 1CGJI 2SGPI 1TBRR 1LR9A 2GKRI 4HGUA 2NU2I 1HDLA 1LR8A 1OYVI 1PCEA 1R0RI 2JYYA 1MT1A 1SGYI 2F3CI 3SGQI 2V53A 1TGSI 1DS3I 2N52A 1CE3A 2SGQI 1CT0I 2XRCA 2NU3I 2B0UC 1SGQI 1CGII 1SGRI 2M5XA 2KMQA 4GI3C 2SGEI 2KMPA 1TUSA 1PPFI 3TJQA 1YU6C 2NU1I 2LEOA 1OMUA 1SGNI 1BMOA 1SGEI 2N17A 1OMTA 3SGBI 1Z7KB 3B4VC 2GKTI 2BUSA 1TURA 2WCYA 4OVOA
chains in the Genus database with same CATH superfamily
1UVGA 1R79A 1CT2I 3OXFA 2KMRA 2WGCA 2GVIA 2K9HA 1FYBA 4SGBI 3MEKA 2NU0I 1CSOI 1TBQR 2ENNA 2V1CC 2L7XA 2N1AB 4FKDA 1V1IA 2E73A 2OVOA 5E3QA 5EX0A 5CCLA 2OZUA 1K7VA 1M8BA 3RU0A 3E2IA 1AN1I 2OU2A 5CCMA 5JHWC 3R5AA 4B6DA 3UEYA 1S20A 1XBTA 3E59A 1YTPA 1N13A 4AMLA 1KBFA 3SEKC 2KMOA 2ARPF 2Y0MA 1SGPI 1Z2IA 1WKXA 2NU4I 5DAEA 3TOBA 5HQ8A 1HEVA 1NUBA 1UVFA 2JZMA 1HJAI 1VDDA 1DS2I 1PJUA 2VRWB 3QAHA 1FY7A 2GIVA 4UXHA 7WGAA 1ULMA 2KCXA 1WGTA 3VDPA 1OVOA 2UZ3A 3TO7A 3QTLD 2SGFI 1FAQA 1UHAA 3FSXA 3QWPA 2ODDA 4UXJA 4E1RA 1IY6A 2ORWA 5J8FA 2OD1A 1IY5A 1ULNA 3UFFA 1KBEA 1H0ZA 2JW6A 1K7TA 1Y8FA 1TOTA 1V1HA 3BJIA 4WP4A 3OVOA 2QQCA 2B8TA 3CXLA 1M8CA 3FC3A 1IW4A 1TIHA 1ULKA 1XX6A 1UUCA 1X4SA 2QQDA 4UXIA 1LR7A 3PDNA 2YUUA 3UGLA 2N71A 1BUSA 1W3SA 1KMAA 2SGDI 2QQEA 2GKVA 3OXGA 3R5DA 2JXDA 1RFHA 3HH2C 3FSYA 3VDUA 1HPTA 2CWGA 1CT4I 2P6AC 1MJ9A 2W0TA 1SGDI 1CHOI 2CWFA 2J87A 2L8EA 2ORVA 2DIPA 2ERWA 1Y1BA 1Y1CA 1PTQA 5J8CA 1CGJI 2SGPI 1P9ZA 1W4RA 2E5RA 3D00A 1TBRR 3KY9A 5HI7A 2JA1A 1LR9A 1WTJA 2GKRI 2LB7A 1MJBA 1K7UA 4HGUA 2NU2I 1HDLA 1LR8A 1OYVI 1PCEA 1R0RI 2CWHA 2RIJA 1XA6A 2V1CA 5EX3A 2JYYA 1MT1A 1SGYI 2F3CI 2ROWA 2WVJA 2V53A 4JCVE 1TGSI 1DS3I 2N52A 3SGQI 4E1PA 1U5KA 1MJAA 2SGQI 1CE3A 2UVOA 2YQPA 5FUWA 1CT0I 1WGCA 2XRCA 2DB6A 5FUYA 1P9GA 2NU3I 3UEJA 2B0UC 1SGQI 2X3TA 4L9MA 1CGII 2RC4A 3TOAA 1SGRI 3TO6A 2FNFX 2M5XA 2KMQA 4GI3C 4DNCA 2SGEI 2J9RA 2KMPA 4A24A 1TUSA 3OL0A 3UGIA 1PPFI 2QQ0A 3TJQA 3UGDA 3UOEA 3VE5A 3GOXA 2X52A 1YU6C 2NU1I 3R5CA 1FARA 5FUVA 2DKVA 2LEOA 3TO9A 5FUXA 1Q9BA 3R5BA 1OMUA 1SGNI 1BMOA 4MPIA 2ENZA 2PQ8A 1NXUA 1SGEI 2CJSC 2N17A 1OMTA 5E3PA 5E3RA 3SGBI 1TBNA 2LUYA 1TBOA 1Z7KB 2QPOA 2GKTI 2BUSA 3B4VC 2ELIA 1TURA 1PTRA 3OXLA 2A20A 2WCYA 9WGAA 4OVOA 1X74A
chains in the Genus database with same CATH topology
1UVGA 1R79A 1CT2I 3OXFA 2KMRA 2GVIA 2K9HA 1FYBA 4SGBI 3MEKA 2NU0I 1CSOI 1TBQR 2ENNA 2V1CC 2L7XA 2N1AB 4FKDA 1V1IA 2E73A 2OVOA 5CCLA 5EX0A 1M8BA 3RU0A 3E2IA 1AN1I 5CCMA 5JHWC 4B6DA 3UEYA 1XBTA 3E59A 1YTPA 1N13A 1KBFA 3SEKC 2KMOA 2ARPF 1SGPI 2NU4I 5DAEA 5HQ8A 1NUBA 1UVFA 2JZMA 1HJAI 1VDDA 1DS2I 1PJUA 2VRWB 4UXHA 2KCXA 3VDPA 1OVOA 2UZ3A 3QTLD 2SGFI 1FAQA 3QWPA 2ODDA 4UXJA 4E1RA 1IY6A 2ORWA 1IY5A 2OD1A 3UFFA 1KBEA 1H0ZA 2JW6A 1Y8FA 1TOTA 1V1HA 3BJIA 3OVOA 2QQCA 2B8TA 3CXLA 1M8CA 3FC3A 1IW4A 1TIHA 1XX6A 1UUCA 1X4SA 2QQDA 4UXIA 1LR7A 3PDNA 2YUUA 3UGLA 2N71A 1BUSA 1W3SA 1KMAA 2SGDI 2QQEA 2GKVA 3OXGA 2JXDA 1RFHA 3HH2C 3VDUA 1HPTA 1CT4I 2P6AC 2W0TA 1SGDI 1CHOI 2L8EA 2J87A 2ORVA 2DIPA 2ERWA 1Y1BA 1Y1CA 1PTQA 1CGJI 2SGPI 1W4RA 2E5RA 3D00A 1TBRR 3KY9A 5HI7A 2JA1A 1LR9A 2GKRI 4HGUA 2NU2I 1HDLA 1LR8A 1OYVI 1PCEA 1R0RI 2V1CA 5EX3A 1XA6A 2JYYA 1MT1A 1SGYI 2F3CI 2ROWA 2WVJA 2V53A 4JCVE 1TGSI 1DS3I 2N52A 3SGQI 4E1PA 1U5KA 2SGQI 1CE3A 5FUWA 2YQPA 1CT0I 2XRCA 2DB6A 5FUYA 3UEJA 2NU3I 2B0UC 1SGQI 4L9MA 1CGII 1SGRI 2FNFX 2M5XA 2KMQA 4GI3C 2SGEI 2J9RA 2KMPA 4A24A 1TUSA 3OL0A 3UGIA 1PPFI 2QQ0A 3TJQA 3UGDA 3VE5A 3GOXA 1YU6C 2NU1I 1FARA 5FUVA 2LEOA 5FUXA 1OMUA 1SGNI 1BMOA 2ENZA 1SGEI 2CJSC 2N17A 1OMTA 3SGBI 1TBNA 2LUYA 1TBOA 1Z7KB 2QPOA 2GKTI 2BUSA 3B4VC 2ELIA 1TURA 1PTRA 3OXLA 2A20A 2WCYA 4OVOA 1X74A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1UVG A;  1CT2 I;  2KMR A;  1FYB A;  2NU0 I;  1CSO I;  1TBQ R;  4SGB I;  2OVO A;  1M8B A;  1AN1 I;  5JHW C;  1YTP A;  1N13 A;  3SEK C;  2KMO A;  2ARP F;  1SGP I;  2NU4 I;  5DAE A;  1NUB A;  1UVF A;  2JZM A;  1HJA I;  1DS2 I;  1PJU A;  2KCX A;  1OVO A;  3QTL D;  2SGF I;  1IY6 A;  1IY5 A;  1H0Z A;  3OVO A;  2QQC A;  1M8C A;  1IW4 A;  1TIH A;  1UUC A;  2QQD A;  1LR7 A;  2N71 A;  1BUS A;  1KMA A;  2SGD I;  2GKV A;  2JXD A;  3HH2 C;  1HPT A;  1CT4 I;  2P6A C;  1SGD I;  1CHO I;  2ERW A;  1Y1B A;  1Y1C A;  1CGJ I;  2SGP I;  1TBR R;  1LR9 A;  2GKR I;  4HGU A;  2NU2 I;  1HDL A;  1LR8 A;  1OYV I;  1PCE A;  1R0R I;  2JYY A;  1MT1 A;  1SGY I;  2F3C I;  3SGQ I;  2V53 A;  1TGS I;  1DS3 I;  2N52 A;  1CE3 A;  2SGQ I;  1CT0 I;  2XRC A;  2NU3 I;  2B0U C;  1SGQ I;  1CGI I;  1SGR I;  2M5X A;  2KMQ A;  4GI3 C;  2SGE I;  2KMP A;  1TUS A;  1PPF I;  3TJQ A;  1YU6 C;  2NU1 I;  2LEO A;  1OMU A;  1SGN I;  1BMO A;  1SGE I;  2N17 A;  1OMT A;  3SGB I;  1Z7K B;  3B4V C;  2GKT I;  2BUS A;  1TUR A;  2WCY A;  4OVO A; 
#chains in the Genus database with same CATH topology
 1UVG A;  1R79 A;  1CT2 I;  3OXF A;  2KMR A;  2WGC A;  2GVI A;  2K9H A;  1FYB A;  4SGB I;  3MEK A;  2NU0 I;  1CSO I;  1TBQ R;  2ENN A;  2V1C C;  2L7X A;  2N1A B;  4FKD A;  1V1I A;  2E73 A;  2OVO A;  5E3Q A;  5EX0 A;  5CCL A;  2OZU A;  1K7V A;  1M8B A;  3RU0 A;  3E2I A;  1AN1 I;  2OU2 A;  5CCM A;  5JHW C;  3R5A A;  4B6D A;  3UEY A;  1S20 A;  1XBT A;  3E59 A;  1YTP A;  1N13 A;  4AML A;  1KBF A;  3SEK C;  2KMO A;  2ARP F;  2Y0M A;  1SGP I;  1Z2I A;  1WKX A;  2NU4 I;  5DAE A;  3TOB A;  5HQ8 A;  1HEV A;  1NUB A;  1UVF A;  2JZM A;  1HJA I;  1VDD A;  1DS2 I;  1PJU A;  2VRW B;  3QAH A;  1FY7 A;  2GIV A;  4UXH A;  7WGA A;  1ULM A;  2KCX A;  1WGT A;  3VDP A;  1OVO A;  2UZ3 A;  3TO7 A;  3QTL D;  2SGF I;  1FAQ A;  1UHA A;  3FSX A;  3QWP A;  2ODD A;  4UXJ A;  4E1R A;  1IY6 A;  2ORW A;  5J8F A;  2OD1 A;  1IY5 A;  1ULN A;  3UFF A;  1KBE A;  1H0Z A;  2JW6 A;  1K7T A;  1Y8F A;  1TOT A;  1V1H A;  3BJI A;  4WP4 A;  3OVO A;  2QQC A;  2B8T A;  3CXL A;  1M8C A;  3FC3 A;  1IW4 A;  1TIH A;  1ULK A;  1XX6 A;  1UUC A;  1X4S A;  2QQD A;  4UXI A;  1LR7 A;  3PDN A;  2YUU A;  3UGL A;  2N71 A;  1BUS A;  1W3S A;  1KMA A;  2SGD I;  2QQE A;  2GKV A;  3OXG A;  3R5D A;  2JXD A;  1RFH A;  3HH2 C;  3FSY A;  3VDU A;  1HPT A;  2CWG A;  1CT4 I;  2P6A C;  1MJ9 A;  2W0T A;  1SGD I;  1CHO I;  2CWF A;  2J87 A;  2L8E A;  2ORV A;  2DIP A;  2ERW A;  1Y1B A;  1Y1C A;  1PTQ A;  5J8C A;  1CGJ I;  2SGP I;  1P9Z A;  1W4R A;  2E5R A;  3D00 A;  1TBR R;  3KY9 A;  5HI7 A;  2JA1 A;  1LR9 A;  1WTJ A;  2GKR I;  2LB7 A;  1MJB A;  1K7U A;  4HGU A;  2NU2 I;  1HDL A;  1LR8 A;  1OYV I;  1PCE A;  1R0R I;  2CWH A;  2RIJ A;  1XA6 A;  2V1C A;  5EX3 A;  2JYY A;  1MT1 A;  1SGY I;  2F3C I;  2ROW A;  2WVJ A;  2V53 A;  4JCV E;  1TGS I;  1DS3 I;  2N52 A;  3SGQ I;  4E1P A;  1U5K A;  1MJA A;  2SGQ I;  1CE3 A;  2UVO A;  2YQP A;  5FUW A;  1CT0 I;  1WGC A;  2XRC A;  2DB6 A;  5FUY A;  1P9G A;  2NU3 I;  3UEJ A;  2B0U C;  1SGQ I;  2X3T A;  4L9M A;  1CGI I;  2RC4 A;  3TOA A;  1SGR I;  3TO6 A;  2FNF X;  2M5X A;  2KMQ A;  4GI3 C;  4DNC A;  2SGE I;  2J9R A;  2KMP A;  4A24 A;  1TUS A;  3OL0 A;  3UGI A;  1PPF I;  2QQ0 A;  3TJQ A;  3UGD A;  3UOE A;  3VE5 A;  3GOX A;  2X52 A;  1YU6 C;  2NU1 I;  3R5C A;  1FAR A;  5FUV A;  2DKV A;  2LEO A;  3TO9 A;  5FUX A;  1Q9B A;  3R5B A;  1OMU A;  1SGN I;  1BMO A;  4MPI A;  2ENZ A;  2PQ8 A;  1NXU A;  1SGE I;  2CJS C;  2N17 A;  1OMT A;  5E3P A;  5E3R A;  3SGB I;  1TBN A;  2LUY A;  1TBO A;  1Z7K B;  2QPO A;  2GKT I;  2BUS A;  3B4V C;  2ELI A;  1TUR A;  1PTR A;  3OXL A;  2A20 A;  2WCY A;  9WGA A;  4OVO A;  1X74 A; 
#chains in the Genus database with same CATH homology
 1UVG A;  1R79 A;  1CT2 I;  3OXF A;  2KMR A;  2GVI A;  2K9H A;  1FYB A;  4SGB I;  3MEK A;  2NU0 I;  1CSO I;  1TBQ R;  2ENN A;  2V1C C;  2L7X A;  2N1A B;  4FKD A;  1V1I A;  2E73 A;  2OVO A;  5CCL A;  5EX0 A;  1M8B A;  3RU0 A;  3E2I A;  1AN1 I;  5CCM A;  5JHW C;  4B6D A;  3UEY A;  1XBT A;  3E59 A;  1YTP A;  1N13 A;  1KBF A;  3SEK C;  2KMO A;  2ARP F;  1SGP I;  2NU4 I;  5DAE A;  5HQ8 A;  1NUB A;  1UVF A;  2JZM A;  1HJA I;  1VDD A;  1DS2 I;  1PJU A;  2VRW B;  4UXH A;  2KCX A;  3VDP A;  1OVO A;  2UZ3 A;  3QTL D;  2SGF I;  1FAQ A;  3QWP A;  2ODD A;  4UXJ A;  4E1R A;  1IY6 A;  2ORW A;  1IY5 A;  2OD1 A;  3UFF A;  1KBE A;  1H0Z A;  2JW6 A;  1Y8F A;  1TOT A;  1V1H A;  3BJI A;  3OVO A;  2QQC A;  2B8T A;  3CXL A;  1M8C A;  3FC3 A;  1IW4 A;  1TIH A;  1XX6 A;  1UUC A;  1X4S A;  2QQD A;  4UXI A;  1LR7 A;  3PDN A;  2YUU A;  3UGL A;  2N71 A;  1BUS A;  1W3S A;  1KMA A;  2SGD I;  2QQE A;  2GKV A;  3OXG A;  2JXD A;  1RFH A;  3HH2 C;  3VDU A;  1HPT A;  1CT4 I;  2P6A C;  2W0T A;  1SGD I;  1CHO I;  2L8E A;  2J87 A;  2ORV A;  2DIP A;  2ERW A;  1Y1B A;  1Y1C A;  1PTQ A;  1CGJ I;  2SGP I;  1W4R A;  2E5R A;  3D00 A;  1TBR R;  3KY9 A;  5HI7 A;  2JA1 A;  1LR9 A;  2GKR I;  4HGU A;  2NU2 I;  1HDL A;  1LR8 A;  1OYV I;  1PCE A;  1R0R I;  2V1C A;  5EX3 A;  1XA6 A;  2JYY A;  1MT1 A;  1SGY I;  2F3C I;  2ROW A;  2WVJ A;  2V53 A;  4JCV E;  1TGS I;  1DS3 I;  2N52 A;  3SGQ I;  4E1P A;  1U5K A;  2SGQ I;  1CE3 A;  5FUW A;  2YQP A;  1CT0 I;  2XRC A;  2DB6 A;  5FUY A;  3UEJ A;  2NU3 I;  2B0U C;  1SGQ I;  4L9M A;  1CGI I;  1SGR I;  2FNF X;  2M5X A;  2KMQ A;  4GI3 C;  2SGE I;  2J9R A;  2KMP A;  4A24 A;  1TUS A;  3OL0 A;  3UGI A;  1PPF I;  2QQ0 A;  3TJQ A;  3UGD A;  3VE5 A;  3GOX A;  1YU6 C;  2NU1 I;  1FAR A;  5FUV A;  2LEO A;  5FUX A;  1OMU A;  1SGN I;  1BMO A;  2ENZ A;  1SGE I;  2CJS C;  2N17 A;  1OMT A;  3SGB I;  1TBN A;  2LUY A;  1TBO A;  1Z7K B;  2QPO A;  2GKT I;  2BUS A;  3B4V C;  2ELI A;  1TUR A;  1PTR A;  3OXL A;  2A20 A;  2WCY A;  4OVO A;  1X74 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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