1AN1I

Leech-derived tryptase inhibitor/trypsin complex
Total Genus 9
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
9
sequence length
40
structure length
40
Chain Sequence
KVCACPKILKPVCGSDGRTYANSCIARCNGVSIKSEGSCP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of the complex of leech-derived tryptase inhibitor (LDTI) with trypsin and modeling of the LDTI-tryptase system.
pubmed doi rcsb
molecule tags Complex (serine protease/inhibitor)
source organism Sus scrofa
molecule keywords TRYPSIN
total genus 9
structure length 40
sequence length 40
ec nomenclature
pdb deposition date 1997-06-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
I PF00050 Kazal_1 Kazal-type serine protease inhibitor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.60.30 Alpha Beta 2-Layer Sandwich Wheat Germ Agglutinin (Isolectin 2); domain 1 Wheat Germ Agglutinin (Isolectin 2); domain 1 1an1I00
2SGQI 1UVGA 1CGJI 2OVOA 1TGSI 2SGEI 1CT2I 1CGII 1PCEA 4OVOA 1CSOI 3TJQA 2P6AC 1TURA 2M5XA 1AN1I 2GKTI 1M8CA 5JHWC 1PJUA 2KMPA 2GKRI 3OVOA 4GI3C 2N17A 1SGEI 1HJAI 1N13A 1HPTA 4HGUA 3SGQI 1BUSA 2F3CI 1PPFI 2N71A 1LR9A 1Z7KB 2NU2I 1IW4A 1OYVI 1SGPI 1CHOI 1IY5A 1Y1BA 1TBQR 1SGQI 1CE3A 2JYYA 2SGDI 2N52A 2JXDA 2LEOA 3QTLD 4SGBI 1LR8A 3SEKC 2B0UC 1OMTA 1TIHA 1IY6A 2NU4I 1YTPA 2SGFI 2SGPI 1FYBA 1DS2I 1SGRI 2QQCA 2JZMA 2QQDA 1M8BA 1CT4I 1TUSA 2V53A 2KMQA 1DS3I 1CT0I 1SGNI 1SGDI 2KCXA 1R0RI 1UVFA 1H0ZA 3SGBI 1BMOA 2BUSA 1MT1A 1OMUA 2NU3I 2KMOA 1HDLA 3HH2C 1TBRR 1OVOA 1YU6C 2ERWA 1LR7A 2GKVA 2XRCA 2WCYA 1KMAA 1NUBA 1UUCA 2ARPF 1Y1CA 2NU0I 2NU1I 5DAEA 3B4VC 2KMRA 1SGYI
chains in the Genus database with same CATH superfamily
4UXHA 2DIPA 2ORWA 2X52A 1S20A 2W0TA 2SGQI 2X3TA 3VDUA 5E3QA 7WGAA 3MEKA 2OU2A 1UVGA 4E1RA 3UEYA 1CGJI 1WTJA 2ENZA 2OVOA 4A24A 1ULMA 3UFFA 2CWFA 2RIJA 5HQ8A 5FUYA 1PTRA 3TO6A 1U5KA 3RU0A 9WGAA 2CWGA 2ODDA 2K9HA 1TGSI 2SGEI 1CT2I 2GIVA 1CGII 1PCEA 4OVOA 2DKVA 5E3RA 1CSOI 4B6DA 3R5DA 3TJQA 1Y8FA 1TURA 2P6AC 3QWPA 2M5XA 4UXIA 1AN1I 2B8TA 2GKTI 1M8CA 2J87A 2YUUA 2CWHA 5HI7A 1PJUA 2JA1A 5JHWC 2KMPA 2GKRI 2UZ3A 3BJIA 5EX3A 1V1IA 3OVOA 3OL0A 1MJ9A 4GI3C 3TO7A 4JCVE 3OXFA 5J8FA 3E59A 3PDNA 1W3SA 4DNCA 2JW6A 2QQ0A 2VRWB 2N17A 1SGEI 1HJAI 1N13A 3QAHA 1HPTA 4HGUA 5FUWA 3R5BA 1MJAA 3SGQI 1TBOA 2YQPA 2QQEA 1BUSA 2GVIA 3GOXA 1P9ZA 1PPFI 2N71A 1LR9A 1TBNA 5FUXA 1Z7KB 1KBEA 2NU2I 1Q9BA 1IW4A 1OYVI 1SGPI 4UXJA 1CHOI 1KBFA 1FAQA 1IY5A 1TOTA 3VE5A 1Y1BA 1RFHA 3UGIA 1NXUA 3FSYA 2WGCA 1TBQR 3UOEA 1SGQI 2KMRA 3FSXA 2JYYA 2SGDI 4FKDA 2N52A 1K7TA 3CXLA 1CE3A 5E3PA 2JXDA 2OZUA 1WGCA 2LEOA 2QPOA 3QTLD 2OD1A 4SGBI 1LR8A 3SEKC 2B0UC 2LB7A 3OXLA 1MJBA 3TOAA 2N1AB 1OMTA 1WGTA 2WVJA 1HEVA 1XA6A 2ROWA 1K7UA 1TIHA 5FUVA 5J8CA 3FC3A 1K7VA 2DB6A 1IY6A 2E5RA 3OXGA 2NU4I 2PQ8A 1YTPA 2SGFI 1W4RA 1X4SA 2SGPI 3TOBA 2CJSC 1FYBA 1DS2I 1SGRI 2QQCA 2JZMA 3D00A 2QQDA 2E73A 4AMLA 1M8BA 1CT4I 1TUSA 1WKXA 1Z2IA 2UVOA 2ELIA 1P9GA 2Y0MA 4L9MA 3UEJA 2V53A 1R79A 1ULKA 2KMQA 1DS3I 1CT0I 2A20A 2ORVA 2RC4A 5CCLA 4WP4A 1SGNI 4E1PA 1SGDI 2KCXA 1R0RI 1UVFA 1H0ZA 1XBTA 3SGBI 4MPIA 2LUYA 1XX6A 5CCMA 1BMOA 1FARA 2BUSA 3R5CA 1MT1A 3VDPA 1OMUA 1X74A 1ULNA 2NU3I 2KMOA 1UHAA 1HDLA 2J9RA 3HH2C 1TBRR 3UGLA 1OVOA 3E2IA 1YU6C 2ERWA 1LR7A 2GKVA 3TO9A 2XRCA 1VDDA 2FNFX 2WCYA 1KMAA 1NUBA 2L8EA 1V1HA 1UUCA 2ENNA 2ARPF 5EX0A 1FY7A 3R5AA 3UGDA 1Y1CA 1PTQA 2NU0I 2L7XA 2NU1I 2V1CA 3B4VC 5DAEA 2V1CC 3KY9A 2F3CI 1SGYI
chains in the Genus database with same CATH topology
4UXHA 2DIPA 2ORWA 2W0TA 2SGQI 3VDUA 3MEKA 4E1RA 1UVGA 3UEYA 1CGJI 2OVOA 2ENZA 4A24A 3UFFA 5HQ8A 5FUYA 1PTRA 1U5KA 3RU0A 2ODDA 2K9HA 1TGSI 2SGEI 1CT2I 1CGII 1PCEA 4OVOA 1CSOI 4B6DA 3TJQA 1Y8FA 1TURA 2P6AC 3QWPA 2M5XA 4UXIA 1AN1I 2B8TA 2GKTI 1M8CA 2J87A 2YUUA 5HI7A 5JHWC 1PJUA 2JA1A 2KMPA 2GKRI 2UZ3A 3BJIA 5EX3A 1V1IA 3OVOA 3OL0A 4GI3C 4JCVE 3OXFA 3E59A 3PDNA 1W3SA 2JW6A 2QQ0A 2VRWB 2N17A 1SGEI 1HJAI 1N13A 1HPTA 4HGUA 5FUWA 3SGQI 1TBOA 2YQPA 2QQEA 1BUSA 2GVIA 3GOXA 1PPFI 2N71A 1LR9A 1TBNA 5FUXA 1Z7KB 1KBEA 2NU2I 1KBFA 1IW4A 1OYVI 1SGPI 4UXJA 1CHOI 1FAQA 1IY5A 1TOTA 3VE5A 1Y1BA 1RFHA 3UGIA 1TBQR 1SGQI 2KMRA 1CE3A 2JYYA 2SGDI 4FKDA 2N52A 3CXLA 2JXDA 2LEOA 2QPOA 3QTLD 2OD1A 4SGBI 1LR8A 3SEKC 2B0UC 3OXLA 2N1AB 1OMTA 2WVJA 1XA6A 2ROWA 1TIHA 5FUVA 3FC3A 2DB6A 1IY6A 2E5RA 3OXGA 2NU4I 1YTPA 2SGFI 1W4RA 1X4SA 2SGPI 2CJSC 1FYBA 1DS2I 1SGRI 2QQCA 2JZMA 3D00A 2QQDA 2E73A 1M8BA 1CT4I 1TUSA 4L9MA 3UEJA 2ELIA 2V53A 1R79A 2KMQA 1DS3I 2A20A 1CT0I 2ORVA 5CCLA 1SGNI 4E1PA 1SGDI 2KCXA 1R0RI 1UVFA 1H0ZA 1XBTA 3SGBI 2LUYA 1XX6A 5CCMA 1BMOA 2BUSA 1FARA 3VDPA 1MT1A 1OMUA 1X74A 2NU3I 2KMOA 1HDLA 2J9RA 3HH2C 1TBRR 3UGLA 1OVOA 3E2IA 1YU6C 2ERWA 1LR7A 2GKVA 2XRCA 1VDDA 2FNFX 2WCYA 1KMAA 1NUBA 2L8EA 1UUCA 1V1HA 2ENNA 2ARPF 5EX0A 3UGDA 1Y1CA 1PTQA 2NU0I 2L7XA 2NU1I 2V1CA 3B4VC 5DAEA 2V1CC 3KY9A 2F3CI 1SGYI
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2SGQ I;  1UVG A;  1CGJ I;  2OVO A;  1TGS I;  2SGE I;  1CT2 I;  1CGI I;  1PCE A;  4OVO A;  1CSO I;  3TJQ A;  2P6A C;  1TUR A;  2M5X A;  1AN1 I;  2GKT I;  1M8C A;  5JHW C;  1PJU A;  2KMP A;  2GKR I;  3OVO A;  4GI3 C;  2N17 A;  1SGE I;  1HJA I;  1N13 A;  1HPT A;  4HGU A;  3SGQ I;  1BUS A;  2F3C I;  1PPF I;  2N71 A;  1LR9 A;  1Z7K B;  2NU2 I;  1IW4 A;  1OYV I;  1SGP I;  1CHO I;  1IY5 A;  1Y1B A;  1TBQ R;  1SGQ I;  1CE3 A;  2JYY A;  2SGD I;  2N52 A;  2JXD A;  2LEO A;  3QTL D;  4SGB I;  1LR8 A;  3SEK C;  2B0U C;  1OMT A;  1TIH A;  1IY6 A;  2NU4 I;  1YTP A;  2SGF I;  2SGP I;  1FYB A;  1DS2 I;  1SGR I;  2QQC A;  2JZM A;  2QQD A;  1M8B A;  1CT4 I;  1TUS A;  2V53 A;  2KMQ A;  1DS3 I;  1CT0 I;  1SGN I;  1SGD I;  2KCX A;  1R0R I;  1UVF A;  1H0Z A;  3SGB I;  1BMO A;  2BUS A;  1MT1 A;  1OMU A;  2NU3 I;  2KMO A;  1HDL A;  3HH2 C;  1TBR R;  1OVO A;  1YU6 C;  2ERW A;  1LR7 A;  2GKV A;  2XRC A;  2WCY A;  1KMA A;  1NUB A;  1UUC A;  2ARP F;  1Y1C A;  2NU0 I;  2NU1 I;  5DAE A;  3B4V C;  2KMR A;  1SGY I; 
#chains in the Genus database with same CATH topology
 4UXH A;  2DIP A;  2ORW A;  2X52 A;  1S20 A;  2W0T A;  2SGQ I;  2X3T A;  3VDU A;  5E3Q A;  7WGA A;  3MEK A;  2OU2 A;  1UVG A;  4E1R A;  3UEY A;  1CGJ I;  1WTJ A;  2ENZ A;  2OVO A;  4A24 A;  1ULM A;  3UFF A;  2CWF A;  2RIJ A;  5HQ8 A;  5FUY A;  1PTR A;  3TO6 A;  1U5K A;  3RU0 A;  9WGA A;  2CWG A;  2ODD A;  2K9H A;  1TGS I;  2SGE I;  1CT2 I;  2GIV A;  1CGI I;  1PCE A;  4OVO A;  2DKV A;  5E3R A;  1CSO I;  4B6D A;  3R5D A;  3TJQ A;  1Y8F A;  1TUR A;  2P6A C;  3QWP A;  2M5X A;  4UXI A;  1AN1 I;  2B8T A;  2GKT I;  1M8C A;  2J87 A;  2YUU A;  2CWH A;  5HI7 A;  1PJU A;  2JA1 A;  5JHW C;  2KMP A;  2GKR I;  2UZ3 A;  3BJI A;  5EX3 A;  1V1I A;  3OVO A;  3OL0 A;  1MJ9 A;  4GI3 C;  3TO7 A;  4JCV E;  3OXF A;  5J8F A;  3E59 A;  3PDN A;  1W3S A;  4DNC A;  2JW6 A;  2QQ0 A;  2VRW B;  2N17 A;  1SGE I;  1HJA I;  1N13 A;  3QAH A;  1HPT A;  4HGU A;  5FUW A;  3R5B A;  1MJA A;  3SGQ I;  1TBO A;  2YQP A;  2QQE A;  1BUS A;  2GVI A;  3GOX A;  1P9Z A;  1PPF I;  2N71 A;  1LR9 A;  1TBN A;  5FUX A;  1Z7K B;  1KBE A;  2NU2 I;  1Q9B A;  1IW4 A;  1OYV I;  1SGP I;  4UXJ A;  1CHO I;  1KBF A;  1FAQ A;  1IY5 A;  1TOT A;  3VE5 A;  1Y1B A;  1RFH A;  3UGI A;  1NXU A;  3FSY A;  2WGC A;  1TBQ R;  3UOE A;  1SGQ I;  2KMR A;  3FSX A;  2JYY A;  2SGD I;  4FKD A;  2N52 A;  1K7T A;  3CXL A;  1CE3 A;  5E3P A;  2JXD A;  2OZU A;  1WGC A;  2LEO A;  2QPO A;  3QTL D;  2OD1 A;  4SGB I;  1LR8 A;  3SEK C;  2B0U C;  2LB7 A;  3OXL A;  1MJB A;  3TOA A;  2N1A B;  1OMT A;  1WGT A;  2WVJ A;  1HEV A;  1XA6 A;  2ROW A;  1K7U A;  1TIH A;  5FUV A;  5J8C A;  3FC3 A;  1K7V A;  2DB6 A;  1IY6 A;  2E5R A;  3OXG A;  2NU4 I;  2PQ8 A;  1YTP A;  2SGF I;  1W4R A;  1X4S A;  2SGP I;  3TOB A;  2CJS C;  1FYB A;  1DS2 I;  1SGR I;  2QQC A;  2JZM A;  3D00 A;  2QQD A;  2E73 A;  4AML A;  1M8B A;  1CT4 I;  1TUS A;  1WKX A;  1Z2I A;  2UVO A;  2ELI A;  1P9G A;  2Y0M A;  4L9M A;  3UEJ A;  2V53 A;  1R79 A;  1ULK A;  2KMQ A;  1DS3 I;  1CT0 I;  2A20 A;  2ORV A;  2RC4 A;  5CCL A;  4WP4 A;  1SGN I;  4E1P A;  1SGD I;  2KCX A;  1R0R I;  1UVF A;  1H0Z A;  1XBT A;  3SGB I;  4MPI A;  2LUY A;  1XX6 A;  5CCM A;  1BMO A;  1FAR A;  2BUS A;  3R5C A;  1MT1 A;  3VDP A;  1OMU A;  1X74 A;  1ULN A;  2NU3 I;  2KMO A;  1UHA A;  1HDL A;  2J9R A;  3HH2 C;  1TBR R;  3UGL A;  1OVO A;  3E2I A;  1YU6 C;  2ERW A;  1LR7 A;  2GKV A;  3TO9 A;  2XRC A;  1VDD A;  2FNF X;  2WCY A;  1KMA A;  1NUB A;  2L8E A;  1V1H A;  1UUC A;  2ENN A;  2ARP F;  5EX0 A;  1FY7 A;  3R5A A;  3UGD A;  1Y1C A;  1PTQ A;  2NU0 I;  2L7X A;  2NU1 I;  2V1C A;  3B4V C;  5DAE A;  2V1C C;  3KY9 A;  2F3C I;  1SGY I; 
#chains in the Genus database with same CATH homology
 4UXH A;  2DIP A;  2ORW A;  2W0T A;  2SGQ I;  3VDU A;  3MEK A;  4E1R A;  1UVG A;  3UEY A;  1CGJ I;  2OVO A;  2ENZ A;  4A24 A;  3UFF A;  5HQ8 A;  5FUY A;  1PTR A;  1U5K A;  3RU0 A;  2ODD A;  2K9H A;  1TGS I;  2SGE I;  1CT2 I;  1CGI I;  1PCE A;  4OVO A;  1CSO I;  4B6D A;  3TJQ A;  1Y8F A;  1TUR A;  2P6A C;  3QWP A;  2M5X A;  4UXI A;  1AN1 I;  2B8T A;  2GKT I;  1M8C A;  2J87 A;  2YUU A;  5HI7 A;  5JHW C;  1PJU A;  2JA1 A;  2KMP A;  2GKR I;  2UZ3 A;  3BJI A;  5EX3 A;  1V1I A;  3OVO A;  3OL0 A;  4GI3 C;  4JCV E;  3OXF A;  3E59 A;  3PDN A;  1W3S A;  2JW6 A;  2QQ0 A;  2VRW B;  2N17 A;  1SGE I;  1HJA I;  1N13 A;  1HPT A;  4HGU A;  5FUW A;  3SGQ I;  1TBO A;  2YQP A;  2QQE A;  1BUS A;  2GVI A;  3GOX A;  1PPF I;  2N71 A;  1LR9 A;  1TBN A;  5FUX A;  1Z7K B;  1KBE A;  2NU2 I;  1KBF A;  1IW4 A;  1OYV I;  1SGP I;  4UXJ A;  1CHO I;  1FAQ A;  1IY5 A;  1TOT A;  3VE5 A;  1Y1B A;  1RFH A;  3UGI A;  1TBQ R;  1SGQ I;  2KMR A;  1CE3 A;  2JYY A;  2SGD I;  4FKD A;  2N52 A;  3CXL A;  2JXD A;  2LEO A;  2QPO A;  3QTL D;  2OD1 A;  4SGB I;  1LR8 A;  3SEK C;  2B0U C;  3OXL A;  2N1A B;  1OMT A;  2WVJ A;  1XA6 A;  2ROW A;  1TIH A;  5FUV A;  3FC3 A;  2DB6 A;  1IY6 A;  2E5R A;  3OXG A;  2NU4 I;  1YTP A;  2SGF I;  1W4R A;  1X4S A;  2SGP I;  2CJS C;  1FYB A;  1DS2 I;  1SGR I;  2QQC A;  2JZM A;  3D00 A;  2QQD A;  2E73 A;  1M8B A;  1CT4 I;  1TUS A;  4L9M A;  3UEJ A;  2ELI A;  2V53 A;  1R79 A;  2KMQ A;  1DS3 I;  2A20 A;  1CT0 I;  2ORV A;  5CCL A;  1SGN I;  4E1P A;  1SGD I;  2KCX A;  1R0R I;  1UVF A;  1H0Z A;  1XBT A;  3SGB I;  2LUY A;  1XX6 A;  5CCM A;  1BMO A;  2BUS A;  1FAR A;  3VDP A;  1MT1 A;  1OMU A;  1X74 A;  2NU3 I;  2KMO A;  1HDL A;  2J9R A;  3HH2 C;  1TBR R;  3UGL A;  1OVO A;  3E2I A;  1YU6 C;  2ERW A;  1LR7 A;  2GKV A;  2XRC A;  1VDD A;  2FNF X;  2WCY A;  1KMA A;  1NUB A;  2L8E A;  1UUC A;  1V1H A;  2ENN A;  2ARP F;  5EX0 A;  3UGD A;  1Y1C A;  1PTQ A;  2NU0 I;  2L7X A;  2NU1 I;  2V1C A;  3B4V C;  5DAE A;  2V1C C;  3KY9 A;  2F3C I;  1SGY I; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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