1AN1I

Leech-derived tryptase inhibitor/trypsin complex
Total Genus 9
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
9
sequence length
40
structure length
40
Chain Sequence
KVCACPKILKPVCGSDGRTYANSCIARCNGVSIKSEGSCP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords TRYPSIN
publication title Structure of the complex of leech-derived tryptase inhibitor (LDTI) with trypsin and modeling of the LDTI-tryptase system.
pubmed doi rcsb
source organism Sus scrofa
molecule tags Complex (serine protease/inhibitor)
total genus 9
structure length 40
sequence length 40
ec nomenclature
pdb deposition date 1997-06-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
I PF00050 Kazal_1 Kazal-type serine protease inhibitor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.60.30 Alpha Beta 2-Layer Sandwich Wheat Germ Agglutinin (Isolectin 2); domain 1 Wheat Germ Agglutinin (Isolectin 2); domain 1 1an1I00
3HH2C 2ARPF 2LEOA 1LR8A 2SGPI 1CE3A 1BUSA 2N17A 2GKTI 3TJQA 1PPFI 5JHWC 1CSOI 1LR7A 2JZMA 1NUBA 2QQCA 1CT4I 1UVGA 2ERWA 1TIHA 1TUSA 1UVFA 1PCEA 2NU1I 2F3CI 1YU6C 1OVOA 1IY6A 1OMTA 1OYVI 1CT0I 1IY5A 1LR9A 2N71A 1Z7KB 4HGUA 2KMPA 1HPTA 2WCYA 2NU3I 1HJAI 1SGEI 1TBRR 2SGQI 1TGSI 1R0RI 5DAEA 1SGNI 2GKRI 2KMQA 2XRCA 1M8CA 2KMRA 1SGQI 1CGII 1CT2I 1MT1A 1SGRI 3SEKC 1CGJI 1KMAA 2N52A 1SGPI 3QTLD 1FYBA 1IW4A 2P6AC 2V53A 2B0UC 2SGFI 1TBQR 2SGEI 3SGQI 3B4VC 2KCXA 1M8BA 1BMOA 2BUSA 1YTPA 2QQDA 2KMOA 1DS3I 1SGYI 2NU2I 2OVOA 4GI3C 3SGBI 1AN1I 2JYYA 1CHOI 2M5XA 1Y1BA 1SGDI 1UUCA 1H0ZA 4OVOA 2NU4I 2SGDI 1PJUA 1DS2I 1TURA 1Y1CA 3OVOA 1N13A 1OMUA 2JXDA 2NU0I 4SGBI 1HDLA 2GKVA
chains in the Genus database with same CATH superfamily
3E59A 4L9MA 3HH2C 2B8TA 2ARPF 3KY9A 3UEJA 2LEOA 2GVIA 5J8CA 1LR8A 1UHAA 2SGPI 3RU0A 1CE3A 3UGLA 3FC3A 1ULNA 2N17A 2GKTI 2L7XA 3UGIA 5FUVA 1BUSA 2J87A 3TJQA 1PPFI 4JCVE 2Y0MA 5JHWC 2W0TA 1CSOI 1LR7A 2YUUA 1FY7A 5HI7A 2VRWB 2K9HA 1K7TA 4E1RA 2DB6A 3TOAA 3UGDA 1P9ZA 2L8EA 1VDDA 1FARA 1NUBA 2CWFA 2DKVA 2JZMA 4UXJA 2QQCA 2JA1A 3R5CA 1CT4I 1UVGA 5EX0A 2ERWA 1TIHA 5FUXA 4B6DA 1WGCA 1TUSA 1UVFA 2E5RA 1PCEA 2NU1I 1MJBA 2F3CI 1YU6C 1ULKA 2RC4A 2ODDA 3FSYA 1OVOA 1IY6A 2ENZA 3R5AA 1OMTA 1TOTA 3FSXA 1V1IA 1OYVI 1CT0I 1IY5A 4A24A 2ORVA 1LR9A 2QQ0A 2N71A 4DNCA 1Z7KB 4HGUA 2KMPA 1HPTA 3TO9A 1P9GA 2WCYA 3VE5A 2NU3I 1HJAI 2CJSC 5E3RA 3OL0A 1SGEI 1TBRR 1X74A 3VDUA 1TBNA 2SGQI 3E2IA 1FAQA 4AMLA 1NXUA 3OXGA 1TGSI 1R0RI 5DAEA 1KBFA 1SGNI 2GKRI 1HEVA 3UOEA 2KMQA 2WVJA 1WGTA 2LB7A 4UXIA 2XRCA 1M8CA 2KMRA 2YQPA 2ORWA 4WP4A 1SGQI 4UXHA 1CGII 1TBOA 2V1CA 1CT2I 1MT1A 5CCLA 1Q9BA 1PTRA 1W3SA 5CCMA 1Z2IA 2X3TA 2QQEA 9WGAA 1X4SA 1SGRI 3PDNA 3BJIA 5E3QA 3SEKC 1XX6A 1CGJI 4FKDA 4E1PA 2J9RA 1KMAA 2N52A 1SGPI 3QWPA 1KBEA 3QTLD 3TO7A 1FYBA 2OU2A 1V1HA 2OD1A 3TO6A 1RFHA 1IW4A 2PQ8A 2CWGA 1K7VA 2P6AC 2B0UC 2V53A 2N1AB 2A20A 2SGFI 1TBQR 3D00A 2SGEI 3SGQI 2QPOA 3B4VC 2JW6A 1R79A 2KCXA 3TOBA 1M8BA 5FUWA 3UEYA 1BMOA 2BUSA 1YTPA 2LUYA 2ELIA 2CWHA 1DS3I 1SGYI 1WKXA 2KMOA 2QQDA 3MEKA 2NU2I 1PTQA 1Y8FA 2OVOA 2WGCA 3R5BA 4GI3C 1ULMA 3SGBI 1AN1I 5J8FA 2JYYA 3GOXA 1K7UA 1XBTA 5EX3A 1XA6A 2UVOA 1CHOI 3VDPA 5HQ8A 2M5XA 2ROWA 2V1CC 1Y1BA 2RIJA 1SGDI 1UUCA 2E73A 2X52A 1MJ9A 1H0ZA 4OVOA 2NU4I 2SGDI 1PJUA 1DS2I 3UFFA 3QAHA 5FUYA 1W4RA 1TURA 1Y1CA 4MPIA 2DIPA 3OXFA 1S20A 2UZ3A 2FNFX 3CXLA 5E3PA 7WGAA 3OVOA 1N13A 1OMUA 2JXDA 2NU0I 3R5DA 2GIVA 1WTJA 2GKVA 2OZUA 4SGBI 2ENNA 1HDLA 1MJAA 3OXLA 1U5KA
chains in the Genus database with same CATH topology
3E59A 4L9MA 3HH2C 2B8TA 2ARPF 3KY9A 3UEJA 2LEOA 2GVIA 1LR8A 2SGPI 1CE3A 3RU0A 3UGLA 3FC3A 1BUSA 2N17A 2GKTI 2L7XA 3UGIA 5FUVA 2J87A 3TJQA 1PPFI 4JCVE 5JHWC 2W0TA 1CSOI 1LR7A 2YUUA 5HI7A 2VRWB 2K9HA 4E1RA 2DB6A 3UGDA 2L8EA 1VDDA 1FARA 1NUBA 2JZMA 4UXJA 3VE5A 5FUXA 2QQCA 2JA1A 1CT4I 1UVGA 5EX0A 2ERWA 1TIHA 4B6DA 1TUSA 1UVFA 2E5RA 1PCEA 2NU1I 2F3CI 1YU6C 2ODDA 1OVOA 1IY6A 2ENZA 1OMTA 1TOTA 1V1IA 1OYVI 1CT0I 1IY5A 4A24A 2ORVA 1LR9A 2QQ0A 2N71A 1Z7KB 4HGUA 2KMPA 1HPTA 2WCYA 2NU3I 1HJAI 2CJSC 3OL0A 1SGEI 1TBRR 1X74A 3VDUA 1TBNA 2SGQI 3E2IA 1FAQA 3OXGA 1TGSI 1R0RI 5DAEA 1SGNI 2GKRI 2KMQA 2WVJA 4UXIA 2XRCA 1M8CA 2KMRA 2YQPA 2ORWA 1SGQI 4UXHA 1CGII 1TBOA 2V1CA 1CT2I 1MT1A 5CCLA 1PTRA 1W3SA 5CCMA 2QQEA 1X4SA 1SGRI 3PDNA 3BJIA 3SEKC 1XX6A 1CGJI 4FKDA 4E1PA 2J9RA 1KMAA 2N52A 1SGPI 3QWPA 1KBEA 3QTLD 1FYBA 1V1HA 2OD1A 1RFHA 1IW4A 1KBFA 2P6AC 2V53A 2B0UC 2N1AB 2A20A 2SGFI 1TBQR 3D00A 2SGEI 3SGQI 2QPOA 3B4VC 2JW6A 1R79A 2KCXA 1M8BA 5FUWA 3UEYA 1BMOA 2BUSA 1YTPA 2LUYA 2ELIA 2KMOA 1DS3I 1SGYI 2QQDA 3MEKA 2NU2I 1PTQA 1Y8FA 2OVOA 4GI3C 3SGBI 1AN1I 2JYYA 3GOXA 1XBTA 5EX3A 1XA6A 1CHOI 3VDPA 5HQ8A 2M5XA 2ROWA 2V1CC 1Y1BA 1SGDI 1UUCA 2E73A 1H0ZA 4OVOA 2NU4I 2SGDI 1PJUA 1DS2I 3UFFA 5FUYA 1W4RA 1TURA 1Y1CA 2DIPA 3OXFA 2UZ3A 2FNFX 3CXLA 3OVOA 1N13A 1OMUA 2JXDA 2NU0I 4SGBI 1HDLA 2GKVA 2ENNA 3OXLA 1U5KA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3HH2 C;  2ARP F;  2LEO A;  1LR8 A;  2SGP I;  1CE3 A;  1BUS A;  2N17 A;  2GKT I;  3TJQ A;  1PPF I;  5JHW C;  1CSO I;  1LR7 A;  2JZM A;  1NUB A;  2QQC A;  1CT4 I;  1UVG A;  2ERW A;  1TIH A;  1TUS A;  1UVF A;  1PCE A;  2NU1 I;  2F3C I;  1YU6 C;  1OVO A;  1IY6 A;  1OMT A;  1OYV I;  1CT0 I;  1IY5 A;  1LR9 A;  2N71 A;  1Z7K B;  4HGU A;  2KMP A;  1HPT A;  2WCY A;  2NU3 I;  1HJA I;  1SGE I;  1TBR R;  2SGQ I;  1TGS I;  1R0R I;  5DAE A;  1SGN I;  2GKR I;  2KMQ A;  2XRC A;  1M8C A;  2KMR A;  1SGQ I;  1CGI I;  1CT2 I;  1MT1 A;  1SGR I;  3SEK C;  1CGJ I;  1KMA A;  2N52 A;  1SGP I;  3QTL D;  1FYB A;  1IW4 A;  2P6A C;  2V53 A;  2B0U C;  2SGF I;  1TBQ R;  2SGE I;  3SGQ I;  3B4V C;  2KCX A;  1M8B A;  1BMO A;  2BUS A;  1YTP A;  2QQD A;  2KMO A;  1DS3 I;  1SGY I;  2NU2 I;  2OVO A;  4GI3 C;  3SGB I;  1AN1 I;  2JYY A;  1CHO I;  2M5X A;  1Y1B A;  1SGD I;  1UUC A;  1H0Z A;  4OVO A;  2NU4 I;  2SGD I;  1PJU A;  1DS2 I;  1TUR A;  1Y1C A;  3OVO A;  1N13 A;  1OMU A;  2JXD A;  2NU0 I;  4SGB I;  1HDL A;  2GKV A; 
#chains in the Genus database with same CATH topology
 3E59 A;  4L9M A;  3HH2 C;  2B8T A;  2ARP F;  3KY9 A;  3UEJ A;  2LEO A;  2GVI A;  5J8C A;  1LR8 A;  1UHA A;  2SGP I;  3RU0 A;  1CE3 A;  3UGL A;  3FC3 A;  1ULN A;  2N17 A;  2GKT I;  2L7X A;  3UGI A;  5FUV A;  1BUS A;  2J87 A;  3TJQ A;  1PPF I;  4JCV E;  2Y0M A;  5JHW C;  2W0T A;  1CSO I;  1LR7 A;  2YUU A;  1FY7 A;  5HI7 A;  2VRW B;  2K9H A;  1K7T A;  4E1R A;  2DB6 A;  3TOA A;  3UGD A;  1P9Z A;  2L8E A;  1VDD A;  1FAR A;  1NUB A;  2CWF A;  2DKV A;  2JZM A;  4UXJ A;  2QQC A;  2JA1 A;  3R5C A;  1CT4 I;  1UVG A;  5EX0 A;  2ERW A;  1TIH A;  5FUX A;  4B6D A;  1WGC A;  1TUS A;  1UVF A;  2E5R A;  1PCE A;  2NU1 I;  1MJB A;  2F3C I;  1YU6 C;  1ULK A;  2RC4 A;  2ODD A;  3FSY A;  1OVO A;  1IY6 A;  2ENZ A;  3R5A A;  1OMT A;  1TOT A;  3FSX A;  1V1I A;  1OYV I;  1CT0 I;  1IY5 A;  4A24 A;  2ORV A;  1LR9 A;  2QQ0 A;  2N71 A;  4DNC A;  1Z7K B;  4HGU A;  2KMP A;  1HPT A;  3TO9 A;  1P9G A;  2WCY A;  3VE5 A;  2NU3 I;  1HJA I;  2CJS C;  5E3R A;  3OL0 A;  1SGE I;  1TBR R;  1X74 A;  3VDU A;  1TBN A;  2SGQ I;  3E2I A;  1FAQ A;  4AML A;  1NXU A;  3OXG A;  1TGS I;  1R0R I;  5DAE A;  1KBF A;  1SGN I;  2GKR I;  1HEV A;  3UOE A;  2KMQ A;  2WVJ A;  1WGT A;  2LB7 A;  4UXI A;  2XRC A;  1M8C A;  2KMR A;  2YQP A;  2ORW A;  4WP4 A;  1SGQ I;  4UXH A;  1CGI I;  1TBO A;  2V1C A;  1CT2 I;  1MT1 A;  5CCL A;  1Q9B A;  1PTR A;  1W3S A;  5CCM A;  1Z2I A;  2X3T A;  2QQE A;  9WGA A;  1X4S A;  1SGR I;  3PDN A;  3BJI A;  5E3Q A;  3SEK C;  1XX6 A;  1CGJ I;  4FKD A;  4E1P A;  2J9R A;  1KMA A;  2N52 A;  1SGP I;  3QWP A;  1KBE A;  3QTL D;  3TO7 A;  1FYB A;  2OU2 A;  1V1H A;  2OD1 A;  3TO6 A;  1RFH A;  1IW4 A;  2PQ8 A;  2CWG A;  1K7V A;  2P6A C;  2B0U C;  2V53 A;  2N1A B;  2A20 A;  2SGF I;  1TBQ R;  3D00 A;  2SGE I;  3SGQ I;  2QPO A;  3B4V C;  2JW6 A;  1R79 A;  2KCX A;  3TOB A;  1M8B A;  5FUW A;  3UEY A;  1BMO A;  2BUS A;  1YTP A;  2LUY A;  2ELI A;  2CWH A;  1DS3 I;  1SGY I;  1WKX A;  2KMO A;  2QQD A;  3MEK A;  2NU2 I;  1PTQ A;  1Y8F A;  2OVO A;  2WGC A;  3R5B A;  4GI3 C;  1ULM A;  3SGB I;  1AN1 I;  5J8F A;  2JYY A;  3GOX A;  1K7U A;  1XBT A;  5EX3 A;  1XA6 A;  2UVO A;  1CHO I;  3VDP A;  5HQ8 A;  2M5X A;  2ROW A;  2V1C C;  1Y1B A;  2RIJ A;  1SGD I;  1UUC A;  2E73 A;  2X52 A;  1MJ9 A;  1H0Z A;  4OVO A;  2NU4 I;  2SGD I;  1PJU A;  1DS2 I;  3UFF A;  3QAH A;  5FUY A;  1W4R A;  1TUR A;  1Y1C A;  4MPI A;  2DIP A;  3OXF A;  1S20 A;  2UZ3 A;  2FNF X;  3CXL A;  5E3P A;  7WGA A;  3OVO A;  1N13 A;  1OMU A;  2JXD A;  2NU0 I;  3R5D A;  2GIV A;  1WTJ A;  2GKV A;  2OZU A;  4SGB I;  2ENN A;  1HDL A;  1MJA A;  3OXL A;  1U5K A; 
#chains in the Genus database with same CATH homology
 3E59 A;  4L9M A;  3HH2 C;  2B8T A;  2ARP F;  3KY9 A;  3UEJ A;  2LEO A;  2GVI A;  1LR8 A;  2SGP I;  1CE3 A;  3RU0 A;  3UGL A;  3FC3 A;  1BUS A;  2N17 A;  2GKT I;  2L7X A;  3UGI A;  5FUV A;  2J87 A;  3TJQ A;  1PPF I;  4JCV E;  5JHW C;  2W0T A;  1CSO I;  1LR7 A;  2YUU A;  5HI7 A;  2VRW B;  2K9H A;  4E1R A;  2DB6 A;  3UGD A;  2L8E A;  1VDD A;  1FAR A;  1NUB A;  2JZM A;  4UXJ A;  3VE5 A;  5FUX A;  2QQC A;  2JA1 A;  1CT4 I;  1UVG A;  5EX0 A;  2ERW A;  1TIH A;  4B6D A;  1TUS A;  1UVF A;  2E5R A;  1PCE A;  2NU1 I;  2F3C I;  1YU6 C;  2ODD A;  1OVO A;  1IY6 A;  2ENZ A;  1OMT A;  1TOT A;  1V1I A;  1OYV I;  1CT0 I;  1IY5 A;  4A24 A;  2ORV A;  1LR9 A;  2QQ0 A;  2N71 A;  1Z7K B;  4HGU A;  2KMP A;  1HPT A;  2WCY A;  2NU3 I;  1HJA I;  2CJS C;  3OL0 A;  1SGE I;  1TBR R;  1X74 A;  3VDU A;  1TBN A;  2SGQ I;  3E2I A;  1FAQ A;  3OXG A;  1TGS I;  1R0R I;  5DAE A;  1SGN I;  2GKR I;  2KMQ A;  2WVJ A;  4UXI A;  2XRC A;  1M8C A;  2KMR A;  2YQP A;  2ORW A;  1SGQ I;  4UXH A;  1CGI I;  1TBO A;  2V1C A;  1CT2 I;  1MT1 A;  5CCL A;  1PTR A;  1W3S A;  5CCM A;  2QQE A;  1X4S A;  1SGR I;  3PDN A;  3BJI A;  3SEK C;  1XX6 A;  1CGJ I;  4FKD A;  4E1P A;  2J9R A;  1KMA A;  2N52 A;  1SGP I;  3QWP A;  1KBE A;  3QTL D;  1FYB A;  1V1H A;  2OD1 A;  1RFH A;  1IW4 A;  1KBF A;  2P6A C;  2V53 A;  2B0U C;  2N1A B;  2A20 A;  2SGF I;  1TBQ R;  3D00 A;  2SGE I;  3SGQ I;  2QPO A;  3B4V C;  2JW6 A;  1R79 A;  2KCX A;  1M8B A;  5FUW A;  3UEY A;  1BMO A;  2BUS A;  1YTP A;  2LUY A;  2ELI A;  2KMO A;  1DS3 I;  1SGY I;  2QQD A;  3MEK A;  2NU2 I;  1PTQ A;  1Y8F A;  2OVO A;  4GI3 C;  3SGB I;  1AN1 I;  2JYY A;  3GOX A;  1XBT A;  5EX3 A;  1XA6 A;  1CHO I;  3VDP A;  5HQ8 A;  2M5X A;  2ROW A;  2V1C C;  1Y1B A;  1SGD I;  1UUC A;  2E73 A;  1H0Z A;  4OVO A;  2NU4 I;  2SGD I;  1PJU A;  1DS2 I;  3UFF A;  5FUY A;  1W4R A;  1TUR A;  1Y1C A;  2DIP A;  3OXF A;  2UZ3 A;  2FNF X;  3CXL A;  3OVO A;  1N13 A;  1OMU A;  2JXD A;  2NU0 I;  4SGB I;  1HDL A;  2GKV A;  2ENN A;  3OXL A;  1U5K A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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