2KMOA

Solution structure of native leech-derived tryptase inhibitor, ldti
Total Genus 6
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
6
sequence length
44
structure length
44
Chain Sequence
b'KKVCACPKILKPVCGSDGRTYANSCIARCNGVSIKSEGSCPTGI'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Leech-derived tryptase inhibitor C
publication title Deciphering the structural basis that guides the oxidative folding of leech-derived tryptase inhibitor.
pubmed doi rcsb
source organism Hirudo medicinalis
molecule tags Hydrolase
total genus 6
structure length 44
sequence length 44
ec nomenclature
pdb deposition date 2009-08-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00050 Kazal_1 Kazal-type serine protease inhibitor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.60.30 Alpha Beta 2-Layer Sandwich Wheat Germ Agglutinin (Isolectin 2); domain 1 Wheat Germ Agglutinin (Isolectin 2); domain 1 2kmoA00
1TGSI 2KMOA 1DS3I 4GI3C 1LR9A 2N17A 1CE3A 1TURA 2SGPI 1AN1I 1HDLA 1YU6C 2XRCA 1DS2I 3SEKC 1FYBA 1HPTA 2ERWA 1TIHA 2GKTI 1HJAI 1PCEA 1Y1CA 1SGYI 1YTPA 2SGEI 3SGQI 2SGQI 1TBQR 2JYYA 2V53A 1CT0I 1Z7KB 1CGJI 1SGPI 3SGBI 5JHWC 1TBRR 1IY5A 3HH2C 2ARPF 2M5XA 2GKRI 1SGRI 1M8CA 2N71A 2QQCA 2NU1I 1BMOA 2LEOA 4HGUA 1OMUA 1SGQI 1UVGA 2NU4I 2F3CI 1OVOA 1NUBA 1CGII 4SGBI 1OMTA 1UUCA 2JZMA 1LR7A 1IW4A 1H0ZA 1N13A 1CT2I 2BUSA 2P6AC 1CT4I 1OYVI 2NU3I 2SGFI 5DAEA 2KMPA 3OVOA 2N52A 1BUSA 3TJQA 2B0UC 2KMRA 1PJUA 2KMQA 1LR8A 1SGDI 2OVOA 1Y1BA 2JXDA 1MT1A 1CHOI 1R0RI 2SGDI 2KCXA 1PPFI 2QQDA 2WCYA 1KMAA 3B4VC 1IY6A 3QTLD 1TUSA 1UVFA 1CSOI 2GKVA 1M8BA 4OVOA 2NU2I 2NU0I 1SGNI 1SGEI
chains in the Genus database with same CATH superfamily
1ULNA 3TO6A 1TGSI 3UGLA 2JW6A 2KMOA 1DS3I 4GI3C 1V1HA 1LR9A 2N17A 3TO9A 1MJAA 1S20A 2L8EA 4MPIA 1TURA 1CE3A 3OXFA 3VE5A 2SGPI 1AN1I 3OXLA 9WGAA 1R79A 1HDLA 2ORWA 4L9MA 1YU6C 2XRCA 5FUXA 1DS2I 1Y8FA 1XA6A 3SEKC 1HPTA 5CCMA 1MJ9A 1PTRA 2ERWA 2B8TA 3UOEA 1FYBA 2DIPA 1TIHA 5FUVA 3FC3A 3VDPA 3BJIA 2UZ3A 3PDNA 2E73A 2YUUA 2CWHA 4UXIA 2RC4A 1MJBA 2GKTI 1HJAI 1PCEA 5J8FA 2ENZA 3KY9A 2WGCA 1Y1CA 1SGYI 1NXUA 3RU0A 2DB6A 1UHAA 1TOTA 2RIJA 3FSYA 4AMLA 1YTPA 2SGEI 2ODDA 3SGQI 5EX3A 2CJSC 1RFHA 2SGQI 1VDDA 2Y0MA 1K7TA 1X4SA 3R5CA 3FSXA 3TOAA 3TO7A 1TBQR 1V1IA 2LUYA 2JYYA 2V53A 1ULKA 3R5AA 1CT0I 2VRWB 1Z7KB 2JA1A 2OD1A 3VDUA 1CGJI 1SGPI 2J9RA 3SGBI 5CCLA 5JHWC 1TBRR 1IY5A 2DKVA 1KBEA 3HH2C 3R5DA 3CXLA 5E3RA 3UGIA 2ARPF 2M5XA 1X74A 1SGRI 2GKRI 3UFFA 2GIVA 1M8CA 2N71A 2V1CC 4A24A 2QQCA 4UXJA 2NU1I 1BMOA 2LEOA 4HGUA 2X3TA 1OMUA 2L7XA 1SGQI 7WGAA 1XX6A 2OU2A 2ELIA 3OXGA 1UVGA 2NU4I 5HQ8A 1W3SA 2F3CI 1OVOA 4UXHA 1WKXA 2A20A 1HEVA 1NUBA 1WGTA 1CGII 3QAHA 4SGBI 5FUYA 2PQ8A 1OMTA 3MEKA 2N1AB 4JCVE 1UUCA 3E2IA 2CWFA 2JZMA 4FKDA 1FARA 1LR7A 1K7VA 1TBOA 2W0TA 4WP4A 3UEJA 4B6DA 5J8CA 4DNCA 1IW4A 1H0ZA 1N13A 1CT2I 2BUSA 1P9ZA 2CWGA 1P9GA 2P6AC 1FAQA 1CT4I 1FY7A 3R5BA 3UEYA 1OYVI 2NU3I 5E3PA 2SGFI 2K9HA 5HI7A 1K7UA 1PTQA 2KMPA 5DAEA 3OVOA 5FUWA 2UVOA 2QQ0A 3OL0A 3QWPA 1WGCA 1TBNA 2N52A 3TJQA 2B0UC 1BUSA 4E1RA 1KBFA 2KMRA 3TOBA 1PJUA 2KMQA 1LR8A 1WTJA 1Z2IA 1SGDI 2GVIA 2OVOA 2V1CA 1Y1BA 2JXDA 2QPOA 1MT1A 5E3QA 2WVJA 2LB7A 1CHOI 1R0RI 2SGDI 2ROWA 2OZUA 2X52A 1U5KA 2QQEA 5EX0A 2KCXA 1PPFI 2QQDA 2WCYA 1KMAA 3B4VC 1IY6A 1XBTA 3QTLD 3E59A 1TUSA 1UVFA 4E1PA 2J87A 1CSOI 2ENNA 1Q9BA 2GKVA 2YQPA 1M8BA 4OVOA 1W4RA 1ULMA 3GOXA 2NU2I 2FNFX 2ORVA 2NU0I 1SGNI 1SGEI 3D00A 3UGDA 2E5RA
chains in the Genus database with same CATH topology
1TGSI 3UGLA 2JW6A 2KMOA 1DS3I 4GI3C 1V1HA 1LR9A 2N17A 1CE3A 2L8EA 1TURA 3OXFA 3VE5A 2SGPI 1AN1I 3OXLA 1R79A 1HDLA 2ORWA 4L9MA 1YU6C 2XRCA 5FUXA 1DS2I 1Y8FA 1XA6A 3SEKC 1HPTA 5CCMA 2ERWA 1PTRA 1FYBA 2B8TA 2DIPA 1TIHA 5FUVA 3FC3A 3VDPA 3BJIA 2UZ3A 3PDNA 2E73A 2YUUA 4UXIA 2GKTI 1HJAI 1PCEA 2ENZA 3KY9A 1Y1CA 1SGYI 3RU0A 2DB6A 1TOTA 1YTPA 2SGEI 2ODDA 3SGQI 5EX3A 2CJSC 1RFHA 2SGQI 1VDDA 1X4SA 1TBQR 1V1IA 2LUYA 2JYYA 2V53A 1CT0I 2VRWB 1Z7KB 2JA1A 2OD1A 3VDUA 1CGJI 1SGPI 2J9RA 3SGBI 5CCLA 5JHWC 1TBRR 1IY5A 1KBEA 3HH2C 3CXLA 3UGIA 2ARPF 2M5XA 1X74A 1SGRI 2GKRI 3UFFA 1M8CA 2N71A 2V1CC 4A24A 2QQCA 4UXJA 2NU1I 1BMOA 2LEOA 4HGUA 1OMUA 2L7XA 1SGQI 1XX6A 2ELIA 3OXGA 1UVGA 2NU4I 5HQ8A 1W3SA 2F3CI 1OVOA 4UXHA 2A20A 1NUBA 1CGII 4SGBI 5FUYA 1OMTA 3MEKA 2N1AB 4JCVE 1UUCA 3E2IA 2JZMA 4FKDA 1FARA 1LR7A 1TBOA 2W0TA 3UEJA 4B6DA 1IW4A 1H0ZA 1N13A 1CT2I 2BUSA 2P6AC 1FAQA 1CT4I 3UEYA 1OYVI 2NU3I 2SGFI 2K9HA 5HI7A 1PTQA 2KMPA 5DAEA 3OVOA 5FUWA 2QQ0A 3OL0A 3QWPA 1TBNA 2N52A 3TJQA 2B0UC 1BUSA 4E1RA 1KBFA 2KMRA 1PJUA 2KMQA 1LR8A 1SGDI 2GVIA 2OVOA 2V1CA 1Y1BA 2JXDA 2QPOA 1MT1A 2WVJA 1CHOI 1R0RI 2SGDI 2ROWA 1U5KA 2QQEA 5EX0A 2KCXA 1PPFI 2QQDA 2WCYA 1KMAA 3B4VC 1IY6A 1XBTA 3QTLD 3E59A 1TUSA 1UVFA 4E1PA 2J87A 1CSOI 2ENNA 2GKVA 2YQPA 1M8BA 4OVOA 1W4RA 3GOXA 2NU2I 2FNFX 2ORVA 2NU0I 1SGNI 1SGEI 3D00A 3UGDA 2E5RA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1TGS I;  2KMO A;  1DS3 I;  4GI3 C;  1LR9 A;  2N17 A;  1CE3 A;  1TUR A;  2SGP I;  1AN1 I;  1HDL A;  1YU6 C;  2XRC A;  1DS2 I;  3SEK C;  1FYB A;  1HPT A;  2ERW A;  1TIH A;  2GKT I;  1HJA I;  1PCE A;  1Y1C A;  1SGY I;  1YTP A;  2SGE I;  3SGQ I;  2SGQ I;  1TBQ R;  2JYY A;  2V53 A;  1CT0 I;  1Z7K B;  1CGJ I;  1SGP I;  3SGB I;  5JHW C;  1TBR R;  1IY5 A;  3HH2 C;  2ARP F;  2M5X A;  2GKR I;  1SGR I;  1M8C A;  2N71 A;  2QQC A;  2NU1 I;  1BMO A;  2LEO A;  4HGU A;  1OMU A;  1SGQ I;  1UVG A;  2NU4 I;  2F3C I;  1OVO A;  1NUB A;  1CGI I;  4SGB I;  1OMT A;  1UUC A;  2JZM A;  1LR7 A;  1IW4 A;  1H0Z A;  1N13 A;  1CT2 I;  2BUS A;  2P6A C;  1CT4 I;  1OYV I;  2NU3 I;  2SGF I;  5DAE A;  2KMP A;  3OVO A;  2N52 A;  1BUS A;  3TJQ A;  2B0U C;  2KMR A;  1PJU A;  2KMQ A;  1LR8 A;  1SGD I;  2OVO A;  1Y1B A;  2JXD A;  1MT1 A;  1CHO I;  1R0R I;  2SGD I;  2KCX A;  1PPF I;  2QQD A;  2WCY A;  1KMA A;  3B4V C;  1IY6 A;  3QTL D;  1TUS A;  1UVF A;  1CSO I;  2GKV A;  1M8B A;  4OVO A;  2NU2 I;  2NU0 I;  1SGN I;  1SGE I; 
#chains in the Genus database with same CATH topology
 1ULN A;  3TO6 A;  1TGS I;  3UGL A;  2JW6 A;  2KMO A;  1DS3 I;  4GI3 C;  1V1H A;  1LR9 A;  2N17 A;  3TO9 A;  1MJA A;  1S20 A;  2L8E A;  4MPI A;  1TUR A;  1CE3 A;  3OXF A;  3VE5 A;  2SGP I;  1AN1 I;  3OXL A;  9WGA A;  1R79 A;  1HDL A;  2ORW A;  4L9M A;  1YU6 C;  2XRC A;  5FUX A;  1DS2 I;  1Y8F A;  1XA6 A;  3SEK C;  1HPT A;  5CCM A;  1MJ9 A;  1PTR A;  2ERW A;  2B8T A;  3UOE A;  1FYB A;  2DIP A;  1TIH A;  5FUV A;  3FC3 A;  3VDP A;  3BJI A;  2UZ3 A;  3PDN A;  2E73 A;  2YUU A;  2CWH A;  4UXI A;  2RC4 A;  1MJB A;  2GKT I;  1HJA I;  1PCE A;  5J8F A;  2ENZ A;  3KY9 A;  2WGC A;  1Y1C A;  1SGY I;  1NXU A;  3RU0 A;  2DB6 A;  1UHA A;  1TOT A;  2RIJ A;  3FSY A;  4AML A;  1YTP A;  2SGE I;  2ODD A;  3SGQ I;  5EX3 A;  2CJS C;  1RFH A;  2SGQ I;  1VDD A;  2Y0M A;  1K7T A;  1X4S A;  3R5C A;  3FSX A;  3TOA A;  3TO7 A;  1TBQ R;  1V1I A;  2LUY A;  2JYY A;  2V53 A;  1ULK A;  3R5A A;  1CT0 I;  2VRW B;  1Z7K B;  2JA1 A;  2OD1 A;  3VDU A;  1CGJ I;  1SGP I;  2J9R A;  3SGB I;  5CCL A;  5JHW C;  1TBR R;  1IY5 A;  2DKV A;  1KBE A;  3HH2 C;  3R5D A;  3CXL A;  5E3R A;  3UGI A;  2ARP F;  2M5X A;  1X74 A;  1SGR I;  2GKR I;  3UFF A;  2GIV A;  1M8C A;  2N71 A;  2V1C C;  4A24 A;  2QQC A;  4UXJ A;  2NU1 I;  1BMO A;  2LEO A;  4HGU A;  2X3T A;  1OMU A;  2L7X A;  1SGQ I;  7WGA A;  1XX6 A;  2OU2 A;  2ELI A;  3OXG A;  1UVG A;  2NU4 I;  5HQ8 A;  1W3S A;  2F3C I;  1OVO A;  4UXH A;  1WKX A;  2A20 A;  1HEV A;  1NUB A;  1WGT A;  1CGI I;  3QAH A;  4SGB I;  5FUY A;  2PQ8 A;  1OMT A;  3MEK A;  2N1A B;  4JCV E;  1UUC A;  3E2I A;  2CWF A;  2JZM A;  4FKD A;  1FAR A;  1LR7 A;  1K7V A;  1TBO A;  2W0T A;  4WP4 A;  3UEJ A;  4B6D A;  5J8C A;  4DNC A;  1IW4 A;  1H0Z A;  1N13 A;  1CT2 I;  2BUS A;  1P9Z A;  2CWG A;  1P9G A;  2P6A C;  1FAQ A;  1CT4 I;  1FY7 A;  3R5B A;  3UEY A;  1OYV I;  2NU3 I;  5E3P A;  2SGF I;  2K9H A;  5HI7 A;  1K7U A;  1PTQ A;  2KMP A;  5DAE A;  3OVO A;  5FUW A;  2UVO A;  2QQ0 A;  3OL0 A;  3QWP A;  1WGC A;  1TBN A;  2N52 A;  3TJQ A;  2B0U C;  1BUS A;  4E1R A;  1KBF A;  2KMR A;  3TOB A;  1PJU A;  2KMQ A;  1LR8 A;  1WTJ A;  1Z2I A;  1SGD I;  2GVI A;  2OVO A;  2V1C A;  1Y1B A;  2JXD A;  2QPO A;  1MT1 A;  5E3Q A;  2WVJ A;  2LB7 A;  1CHO I;  1R0R I;  2SGD I;  2ROW A;  2OZU A;  2X52 A;  1U5K A;  2QQE A;  5EX0 A;  2KCX A;  1PPF I;  2QQD A;  2WCY A;  1KMA A;  3B4V C;  1IY6 A;  1XBT A;  3QTL D;  3E59 A;  1TUS A;  1UVF A;  4E1P A;  2J87 A;  1CSO I;  2ENN A;  1Q9B A;  2GKV A;  2YQP A;  1M8B A;  4OVO A;  1W4R A;  1ULM A;  3GOX A;  2NU2 I;  2FNF X;  2ORV A;  2NU0 I;  1SGN I;  1SGE I;  3D00 A;  3UGD A;  2E5R A; 
#chains in the Genus database with same CATH homology
 1TGS I;  3UGL A;  2JW6 A;  2KMO A;  1DS3 I;  4GI3 C;  1V1H A;  1LR9 A;  2N17 A;  1CE3 A;  2L8E A;  1TUR A;  3OXF A;  3VE5 A;  2SGP I;  1AN1 I;  3OXL A;  1R79 A;  1HDL A;  2ORW A;  4L9M A;  1YU6 C;  2XRC A;  5FUX A;  1DS2 I;  1Y8F A;  1XA6 A;  3SEK C;  1HPT A;  5CCM A;  2ERW A;  1PTR A;  1FYB A;  2B8T A;  2DIP A;  1TIH A;  5FUV A;  3FC3 A;  3VDP A;  3BJI A;  2UZ3 A;  3PDN A;  2E73 A;  2YUU A;  4UXI A;  2GKT I;  1HJA I;  1PCE A;  2ENZ A;  3KY9 A;  1Y1C A;  1SGY I;  3RU0 A;  2DB6 A;  1TOT A;  1YTP A;  2SGE I;  2ODD A;  3SGQ I;  5EX3 A;  2CJS C;  1RFH A;  2SGQ I;  1VDD A;  1X4S A;  1TBQ R;  1V1I A;  2LUY A;  2JYY A;  2V53 A;  1CT0 I;  2VRW B;  1Z7K B;  2JA1 A;  2OD1 A;  3VDU A;  1CGJ I;  1SGP I;  2J9R A;  3SGB I;  5CCL A;  5JHW C;  1TBR R;  1IY5 A;  1KBE A;  3HH2 C;  3CXL A;  3UGI A;  2ARP F;  2M5X A;  1X74 A;  1SGR I;  2GKR I;  3UFF A;  1M8C A;  2N71 A;  2V1C C;  4A24 A;  2QQC A;  4UXJ A;  2NU1 I;  1BMO A;  2LEO A;  4HGU A;  1OMU A;  2L7X A;  1SGQ I;  1XX6 A;  2ELI A;  3OXG A;  1UVG A;  2NU4 I;  5HQ8 A;  1W3S A;  2F3C I;  1OVO A;  4UXH A;  2A20 A;  1NUB A;  1CGI I;  4SGB I;  5FUY A;  1OMT A;  3MEK A;  2N1A B;  4JCV E;  1UUC A;  3E2I A;  2JZM A;  4FKD A;  1FAR A;  1LR7 A;  1TBO A;  2W0T A;  3UEJ A;  4B6D A;  1IW4 A;  1H0Z A;  1N13 A;  1CT2 I;  2BUS A;  2P6A C;  1FAQ A;  1CT4 I;  3UEY A;  1OYV I;  2NU3 I;  2SGF I;  2K9H A;  5HI7 A;  1PTQ A;  2KMP A;  5DAE A;  3OVO A;  5FUW A;  2QQ0 A;  3OL0 A;  3QWP A;  1TBN A;  2N52 A;  3TJQ A;  2B0U C;  1BUS A;  4E1R A;  1KBF A;  2KMR A;  1PJU A;  2KMQ A;  1LR8 A;  1SGD I;  2GVI A;  2OVO A;  2V1C A;  1Y1B A;  2JXD A;  2QPO A;  1MT1 A;  2WVJ A;  1CHO I;  1R0R I;  2SGD I;  2ROW A;  1U5K A;  2QQE A;  5EX0 A;  2KCX A;  1PPF I;  2QQD A;  2WCY A;  1KMA A;  3B4V C;  1IY6 A;  1XBT A;  3QTL D;  3E59 A;  1TUS A;  1UVF A;  4E1P A;  2J87 A;  1CSO I;  2ENN A;  2GKV A;  2YQP A;  1M8B A;  4OVO A;  1W4R A;  3GOX A;  2NU2 I;  2FNF X;  2ORV A;  2NU0 I;  1SGN I;  1SGE I;  3D00 A;  3UGD A;  2E5R A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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