2KMOA

Solution structure of native leech-derived tryptase inhibitor, ldti
Total Genus 6
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
6
sequence length
44
structure length
44
Chain Sequence
KKVCACPKILKPVCGSDGRTYANSCIARCNGVSIKSEGSCPTGI
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
molecule tags Hydrolase
molecule keywords Leech-derived tryptase inhibitor C
publication title Deciphering the structural basis that guides the oxidative folding of leech-derived tryptase inhibitor.
pubmed doi rcsb
source organism Hirudo medicinalis
total genus 6
structure length 44
sequence length 44
ec nomenclature
pdb deposition date 2009-08-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00050 Kazal_1 Kazal-type serine protease inhibitor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.60.30 Alpha Beta 2-Layer Sandwich Wheat Germ Agglutinin (Isolectin 2); domain 1 Wheat Germ Agglutinin (Isolectin 2); domain 1 2kmoA00
1Y1BA 2P6AC 1FYBA 4GI3C 5DAEA 2SGEI 1SGQI 1UUCA 4OVOA 1YU6C 3TJQA 4HGUA 1SGPI 4SGBI 1PPFI 3SGQI 1IW4A 1SGEI 1HPTA 1MT1A 2NU2I 2QQDA 2N52A 1BMOA 1CT4I 3B4VC 2NU1I 1YTPA 1OVOA 2JXDA 3SGBI 2GKTI 1HDLA 1OMTA 2SGDI 1HJAI 1UVGA 1M8CA 1N13A 1CE3A 1TGSI 2B0UC 2BUSA 1CGJI 1NUBA 2GKRI 2V53A 1CT2I 1TBRR 1SGYI 1UVFA 1IY5A 2GKVA 1IY6A 2ARPF 1M8BA 1BUSA 1SGNI 1DS2I 1TURA 1PJUA 2KMQA 3HH2C 2N71A 1TBQR 3SEKC 2KMRA 1LR7A 2OVOA 3OVOA 2SGQI 1TIHA 1Z7KB 2SGFI 2KMPA 1TUSA 1CHOI 2WCYA 1DS3I 1SGDI 1OMUA 1CSOI 1LR8A 2F3CI 2SGPI 2NU4I 1SGRI 1AN1I 2NU3I 1R0RI 2M5XA 2ERWA 1H0ZA 2N17A 2KCXA 2JYYA 3QTLD 2JZMA 1Y1CA 1PCEA 2KMOA 2NU0I 2XRCA 5JHWC 1OYVI 1LR9A 1CGII 1KMAA 1CT0I 2QQCA 2LEOA
chains in the Genus database with same CATH superfamily
3UOEA 1Y1BA 1K7TA 2P6AC 1FYBA 2QQ0A 2JA1A 3OXGA 3OXFA 5FUXA 2RC4A 2J87A 4GI3C 2DIPA 3UGLA 5E3PA 5DAEA 2LUYA 2SGEI 3TOAA 4B6DA 1SGQI 1UUCA 4OVOA 1RFHA 4UXJA 3TO9A 3UEJA 1YU6C 3TJQA 3TO6A 1Q9BA 2WGCA 4HGUA 1SGPI 1TBOA 3FSXA 4SGBI 4UXHA 2J9RA 1PPFI 1FY7A 5CCMA 3VDUA 3FC3A 2DB6A 3OL0A 1WGTA 2N1AB 3SGQI 3KY9A 1P9ZA 1SGEI 1IW4A 3UEYA 1HPTA 1MT1A 2NU2I 2QQDA 2FNFX 5CCLA 2OZUA 1S20A 1BMOA 2N52A 2QPOA 1Y8FA 4UXIA 1CT4I 5E3RA 7WGAA 3B4VC 1XBTA 2NU1I 2Y0MA 3QWPA 4JCVE 1U5KA 1YTPA 2E73A 2X52A 2A20A 3E59A 1FAQA 1KBFA 3VDPA 1OVOA 2ORVA 2JXDA 3R5BA 2GIVA 2ROWA 3SGBI 2GKTI 5EX3A 2PQ8A 4AMLA 1HDLA 2W0TA 1OMTA 2LB7A 1P9GA 2SGDI 5J8CA 1HJAI 1XA6A 1UVGA 2ENNA 1M8CA 1MJAA 1K7VA 1N13A 1TGSI 2B0UC 4FKDA 3R5CA 2BUSA 1CE3A 2JW6A 1HEVA 1CGJI 1NUBA 2GKRI 2V53A 2YUUA 3QAHA 4A24A 1CT2I 1UHAA 1TBRR 1SGYI 1UVFA 2OD1A 1IY5A 2GKVA 1IY6A 4DNCA 5FUVA 2ARPF 4E1RA 5FUYA 3TO7A 1NXUA 2WCYA 2K9HA 2RIJA 2V1CC 1M8BA 5HQ8A 1XX6A 1SGNI 2CWHA 1BUSA 1DS2I 2X3TA 5EX0A 1ULKA 1ULMA 1WGCA 5HI7A 3UGDA 2DKVA 2UVOA 2ENZA 1TURA 1PJUA 3VE5A 2KMQA 3BJIA 3HH2C 2CWFA 1Z2IA 2N71A 1TBQR 1K7UA 3PDNA 2V1CA 2B8TA 3SEKC 2KMRA 1LR7A 2OVOA 1ULNA 2SGQI 3E2IA 1W4RA 3CXLA 3OVOA 1TIHA 1Z7KB 2E5RA 1MJBA 1TUSA 1CHOI 2KMPA 1DS3I 2SGFI 1SGDI 2WVJA 1V1HA 2GVIA 1PTRA 1R79A 1OMUA 1CSOI 1LR8A 1FARA 2OU2A 2F3CI 2SGPI 1WKXA 1X4SA 2NU4I 1SGRI 3QTLD 1AN1I 5FUWA 2NU3I 2UZ3A 1R0RI 2CJSC 2M5XA 3MEKA 3FSYA 2ERWA 1V1IA 1H0ZA 2ELIA 4L9MA 2YQPA 1KBEA 2N17A 2KCXA 2L7XA 1PTQA 3TOBA 1WTJA 1VDDA 2JYYA 2JZMA 2ODDA 1Y1CA 1PCEA 2QQEA 2KMOA 1X74A 2NU0I 3R5DA 3UFFA 2XRCA 2CWGA 3OXLA 4WP4A 9WGAA 3GOXA 1MJ9A 3D00A 1OYVI 3UGIA 5JHWC 1LR9A 4MPIA 2L8EA 1CGII 1KMAA 3RU0A 3R5AA 5E3QA 1W3SA 1TOTA 2ORWA 4E1PA 5J8FA 1TBNA 1CT0I 2VRWB 2QQCA 2LEOA
chains in the Genus database with same CATH topology
1Y1BA 2P6AC 1FYBA 2QQ0A 2JA1A 3OXGA 3OXFA 5FUXA 4GI3C 2J87A 2DIPA 3UGLA 5DAEA 2LUYA 2SGEI 4B6DA 1SGQI 1UUCA 4OVOA 1RFHA 4UXJA 3UEJA 1YU6C 3TJQA 4HGUA 1SGPI 1TBOA 4SGBI 4UXHA 2J9RA 1PPFI 5CCMA 3FC3A 3VDUA 2DB6A 3OL0A 2N1AB 3SGQI 3KY9A 1SGEI 1IW4A 3UEYA 1HPTA 1MT1A 2NU2I 2QQDA 2FNFX 5CCLA 1BMOA 2N52A 2QPOA 1Y8FA 4UXIA 1CT4I 3B4VC 1XBTA 2NU1I 3QWPA 4JCVE 1U5KA 1YTPA 2E73A 3E59A 2A20A 1FAQA 1KBFA 3VDPA 1OVOA 2ORVA 2JXDA 2ROWA 3SGBI 2GKTI 5EX3A 1HDLA 2W0TA 1OMTA 2SGDI 1HJAI 1XA6A 1UVGA 2ENNA 1M8CA 4FKDA 1N13A 1CE3A 1TGSI 2B0UC 2BUSA 2JW6A 1CGJI 1NUBA 2GKRI 2V53A 2YUUA 4A24A 1CT2I 1TBRR 1SGYI 1UVFA 2OD1A 1IY5A 2GKVA 1IY6A 5FUVA 2ARPF 4E1RA 5FUYA 2K9HA 2V1CC 1M8BA 5HQ8A 1XX6A 1SGNI 1BUSA 1DS2I 5EX0A 3UGDA 5HI7A 2ENZA 1TURA 1PJUA 3VE5A 2KMQA 3BJIA 3HH2C 2N71A 1TBQR 3PDNA 2V1CA 2B8TA 3SEKC 2KMRA 1LR7A 2OVOA 3E2IA 2SGQI 3OVOA 1W4RA 3CXLA 1TIHA 1Z7KB 2E5RA 2KMPA 1TUSA 1CHOI 2SGFI 1DS3I 2WCYA 1SGDI 2WVJA 1V1HA 2GVIA 1PTRA 1R79A 1OMUA 1CSOI 1LR8A 1FARA 2F3CI 2SGPI 1X4SA 2NU4I 1SGRI 3QTLD 1AN1I 5FUWA 2NU3I 2UZ3A 1R0RI 2CJSC 2M5XA 3MEKA 2ERWA 1V1IA 1H0ZA 2ELIA 4L9MA 2YQPA 1KBEA 2N17A 2KCXA 2L7XA 1PTQA 1VDDA 2JYYA 2JZMA 2ODDA 1Y1CA 1PCEA 2QQEA 2KMOA 1X74A 2NU0I 3UFFA 2XRCA 3OXLA 3GOXA 3D00A 1OYVI 3UGIA 5JHWC 1LR9A 2L8EA 1CGII 1KMAA 3RU0A 4E1PA 1TOTA 1W3SA 2ORWA 1TBNA 1CT0I 2VRWB 2QQCA 2LEOA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1Y1B A;  2P6A C;  1FYB A;  4GI3 C;  5DAE A;  2SGE I;  1SGQ I;  1UUC A;  4OVO A;  1YU6 C;  3TJQ A;  4HGU A;  1SGP I;  4SGB I;  1PPF I;  3SGQ I;  1IW4 A;  1SGE I;  1HPT A;  1MT1 A;  2NU2 I;  2QQD A;  2N52 A;  1BMO A;  1CT4 I;  3B4V C;  2NU1 I;  1YTP A;  1OVO A;  2JXD A;  3SGB I;  2GKT I;  1HDL A;  1OMT A;  2SGD I;  1HJA I;  1UVG A;  1M8C A;  1N13 A;  1CE3 A;  1TGS I;  2B0U C;  2BUS A;  1CGJ I;  1NUB A;  2GKR I;  2V53 A;  1CT2 I;  1TBR R;  1SGY I;  1UVF A;  1IY5 A;  2GKV A;  1IY6 A;  2ARP F;  1M8B A;  1BUS A;  1SGN I;  1DS2 I;  1TUR A;  1PJU A;  2KMQ A;  3HH2 C;  2N71 A;  1TBQ R;  3SEK C;  2KMR A;  1LR7 A;  2OVO A;  3OVO A;  2SGQ I;  1TIH A;  1Z7K B;  2SGF I;  2KMP A;  1TUS A;  1CHO I;  2WCY A;  1DS3 I;  1SGD I;  1OMU A;  1CSO I;  1LR8 A;  2F3C I;  2SGP I;  2NU4 I;  1SGR I;  1AN1 I;  2NU3 I;  1R0R I;  2M5X A;  2ERW A;  1H0Z A;  2N17 A;  2KCX A;  2JYY A;  3QTL D;  2JZM A;  1Y1C A;  1PCE A;  2KMO A;  2NU0 I;  2XRC A;  5JHW C;  1OYV I;  1LR9 A;  1CGI I;  1KMA A;  1CT0 I;  2QQC A;  2LEO A; 
#chains in the Genus database with same CATH topology
 3UOE A;  1Y1B A;  1K7T A;  2P6A C;  1FYB A;  2QQ0 A;  2JA1 A;  3OXG A;  3OXF A;  5FUX A;  2RC4 A;  2J87 A;  4GI3 C;  2DIP A;  3UGL A;  5E3P A;  5DAE A;  2LUY A;  2SGE I;  3TOA A;  4B6D A;  1SGQ I;  1UUC A;  4OVO A;  1RFH A;  4UXJ A;  3TO9 A;  3UEJ A;  1YU6 C;  3TJQ A;  3TO6 A;  1Q9B A;  2WGC A;  4HGU A;  1SGP I;  1TBO A;  3FSX A;  4SGB I;  4UXH A;  2J9R A;  1PPF I;  1FY7 A;  5CCM A;  3VDU A;  3FC3 A;  2DB6 A;  3OL0 A;  1WGT A;  2N1A B;  3SGQ I;  3KY9 A;  1P9Z A;  1SGE I;  1IW4 A;  3UEY A;  1HPT A;  1MT1 A;  2NU2 I;  2QQD A;  2FNF X;  5CCL A;  2OZU A;  1S20 A;  1BMO A;  2N52 A;  2QPO A;  1Y8F A;  4UXI A;  1CT4 I;  5E3R A;  7WGA A;  3B4V C;  1XBT A;  2NU1 I;  2Y0M A;  3QWP A;  4JCV E;  1U5K A;  1YTP A;  2E73 A;  2X52 A;  2A20 A;  3E59 A;  1FAQ A;  1KBF A;  3VDP A;  1OVO A;  2ORV A;  2JXD A;  3R5B A;  2GIV A;  2ROW A;  3SGB I;  2GKT I;  5EX3 A;  2PQ8 A;  4AML A;  1HDL A;  2W0T A;  1OMT A;  2LB7 A;  1P9G A;  2SGD I;  5J8C A;  1HJA I;  1XA6 A;  1UVG A;  2ENN A;  1M8C A;  1MJA A;  1K7V A;  1N13 A;  1TGS I;  2B0U C;  4FKD A;  3R5C A;  2BUS A;  1CE3 A;  2JW6 A;  1HEV A;  1CGJ I;  1NUB A;  2GKR I;  2V53 A;  2YUU A;  3QAH A;  4A24 A;  1CT2 I;  1UHA A;  1TBR R;  1SGY I;  1UVF A;  2OD1 A;  1IY5 A;  2GKV A;  1IY6 A;  4DNC A;  5FUV A;  2ARP F;  4E1R A;  5FUY A;  3TO7 A;  1NXU A;  2WCY A;  2K9H A;  2RIJ A;  2V1C C;  1M8B A;  5HQ8 A;  1XX6 A;  1SGN I;  2CWH A;  1BUS A;  1DS2 I;  2X3T A;  5EX0 A;  1ULK A;  1ULM A;  1WGC A;  5HI7 A;  3UGD A;  2DKV A;  2UVO A;  2ENZ A;  1TUR A;  1PJU A;  3VE5 A;  2KMQ A;  3BJI A;  3HH2 C;  2CWF A;  1Z2I A;  2N71 A;  1TBQ R;  1K7U A;  3PDN A;  2V1C A;  2B8T A;  3SEK C;  2KMR A;  1LR7 A;  2OVO A;  1ULN A;  2SGQ I;  3E2I A;  1W4R A;  3CXL A;  3OVO A;  1TIH A;  1Z7K B;  2E5R A;  1MJB A;  1TUS A;  1CHO I;  2KMP A;  1DS3 I;  2SGF I;  1SGD I;  2WVJ A;  1V1H A;  2GVI A;  1PTR A;  1R79 A;  1OMU A;  1CSO I;  1LR8 A;  1FAR A;  2OU2 A;  2F3C I;  2SGP I;  1WKX A;  1X4S A;  2NU4 I;  1SGR I;  3QTL D;  1AN1 I;  5FUW A;  2NU3 I;  2UZ3 A;  1R0R I;  2CJS C;  2M5X A;  3MEK A;  3FSY A;  2ERW A;  1V1I A;  1H0Z A;  2ELI A;  4L9M A;  2YQP A;  1KBE A;  2N17 A;  2KCX A;  2L7X A;  1PTQ A;  3TOB A;  1WTJ A;  1VDD A;  2JYY A;  2JZM A;  2ODD A;  1Y1C A;  1PCE A;  2QQE A;  2KMO A;  1X74 A;  2NU0 I;  3R5D A;  3UFF A;  2XRC A;  2CWG A;  3OXL A;  4WP4 A;  9WGA A;  3GOX A;  1MJ9 A;  3D00 A;  1OYV I;  3UGI A;  5JHW C;  1LR9 A;  4MPI A;  2L8E A;  1CGI I;  1KMA A;  3RU0 A;  3R5A A;  5E3Q A;  1W3S A;  1TOT A;  2ORW A;  4E1P A;  5J8F A;  1TBN A;  1CT0 I;  2VRW B;  2QQC A;  2LEO A; 
#chains in the Genus database with same CATH homology
 1Y1B A;  2P6A C;  1FYB A;  2QQ0 A;  2JA1 A;  3OXG A;  3OXF A;  5FUX A;  4GI3 C;  2J87 A;  2DIP A;  3UGL A;  5DAE A;  2LUY A;  2SGE I;  4B6D A;  1SGQ I;  1UUC A;  4OVO A;  1RFH A;  4UXJ A;  3UEJ A;  1YU6 C;  3TJQ A;  4HGU A;  1SGP I;  1TBO A;  4SGB I;  4UXH A;  2J9R A;  1PPF I;  5CCM A;  3FC3 A;  3VDU A;  2DB6 A;  3OL0 A;  2N1A B;  3SGQ I;  3KY9 A;  1SGE I;  1IW4 A;  3UEY A;  1HPT A;  1MT1 A;  2NU2 I;  2QQD A;  2FNF X;  5CCL A;  1BMO A;  2N52 A;  2QPO A;  1Y8F A;  4UXI A;  1CT4 I;  3B4V C;  1XBT A;  2NU1 I;  3QWP A;  4JCV E;  1U5K A;  1YTP A;  2E73 A;  3E59 A;  2A20 A;  1FAQ A;  1KBF A;  3VDP A;  1OVO A;  2ORV A;  2JXD A;  2ROW A;  3SGB I;  2GKT I;  5EX3 A;  1HDL A;  2W0T A;  1OMT A;  2SGD I;  1HJA I;  1XA6 A;  1UVG A;  2ENN A;  1M8C A;  4FKD A;  1N13 A;  1CE3 A;  1TGS I;  2B0U C;  2BUS A;  2JW6 A;  1CGJ I;  1NUB A;  2GKR I;  2V53 A;  2YUU A;  4A24 A;  1CT2 I;  1TBR R;  1SGY I;  1UVF A;  2OD1 A;  1IY5 A;  2GKV A;  1IY6 A;  5FUV A;  2ARP F;  4E1R A;  5FUY A;  2K9H A;  2V1C C;  1M8B A;  5HQ8 A;  1XX6 A;  1SGN I;  1BUS A;  1DS2 I;  5EX0 A;  3UGD A;  5HI7 A;  2ENZ A;  1TUR A;  1PJU A;  3VE5 A;  2KMQ A;  3BJI A;  3HH2 C;  2N71 A;  1TBQ R;  3PDN A;  2V1C A;  2B8T A;  3SEK C;  2KMR A;  1LR7 A;  2OVO A;  3E2I A;  2SGQ I;  3OVO A;  1W4R A;  3CXL A;  1TIH A;  1Z7K B;  2E5R A;  2KMP A;  1TUS A;  1CHO I;  2SGF I;  1DS3 I;  2WCY A;  1SGD I;  2WVJ A;  1V1H A;  2GVI A;  1PTR A;  1R79 A;  1OMU A;  1CSO I;  1LR8 A;  1FAR A;  2F3C I;  2SGP I;  1X4S A;  2NU4 I;  1SGR I;  3QTL D;  1AN1 I;  5FUW A;  2NU3 I;  2UZ3 A;  1R0R I;  2CJS C;  2M5X A;  3MEK A;  2ERW A;  1V1I A;  1H0Z A;  2ELI A;  4L9M A;  2YQP A;  1KBE A;  2N17 A;  2KCX A;  2L7X A;  1PTQ A;  1VDD A;  2JYY A;  2JZM A;  2ODD A;  1Y1C A;  1PCE A;  2QQE A;  2KMO A;  1X74 A;  2NU0 I;  3UFF A;  2XRC A;  3OXL A;  3GOX A;  3D00 A;  1OYV I;  3UGI A;  5JHW C;  1LR9 A;  2L8E A;  1CGI I;  1KMA A;  3RU0 A;  4E1P A;  1TOT A;  1W3S A;  2ORW A;  1TBN A;  1CT0 I;  2VRW B;  2QQC A;  2LEO A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...