1PPFI

X-ray crystal structure of the complex of human leukocyte elastase (pmn elastase) and the third domain of the turkey ovomucoid inhibitor
Total Genus 13
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
13
sequence length
56
structure length
56
Chain Sequence
LAAVSVDCSEYPKPACTLEYRPLCGSDNKTYGNKCNFCNAVVESNGTLTLSHFGKC
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase/hydrolase inhibitor
molecule keywords HUMAN LEUKOCYTE ELASTASE
publication title X-ray crystal structure of the complex of human leukocyte elastase (PMN elastase) and the third domain of the turkey ovomucoid inhibitor.
pubmed rcsb
source organism Homo sapiens
total genus 13
structure length 56
sequence length 56
ec nomenclature
pdb deposition date 1991-10-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
I PF00050 Kazal_1 Kazal-type serine protease inhibitor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.60.30 Alpha Beta 2-Layer Sandwich Wheat Germ Agglutinin (Isolectin 2); domain 1 Wheat Germ Agglutinin (Isolectin 2); domain 1 1ppfI00
1IY6A 2F3CI 1TUSA 2KCXA 3B4VC 1Z7KB 2SGEI 1PCEA 1DS3I 2SGPI 2ARPF 1M8CA 1TGSI 1DS2I 1PPFI 1SGQI 1N13A 1Y1BA 2NU3I 1YTPA 2GKVA 2N71A 1HDLA 2KMQA 2OVOA 3SGQI 2B0UC 1TBRR 1CT4I 1IW4A 1CHOI 2M5XA 1M8BA 2BUSA 2NU0I 2KMRA 2JYYA 5DAEA 2XRCA 4HGUA 1NUBA 3QTLD 3SGBI 1IY5A 1R0RI 2NU4I 1SGDI 2SGFI 2NU1I 2V53A 2JZMA 5JHWC 1OMUA 2ERWA 1YU6C 1LR9A 1TURA 1H0ZA 1OMTA 1OYVI 1CT0I 4GI3C 1PJUA 1CT2I 1LR7A 1OVOA 1SGEI 2N52A 2GKRI 2SGQI 2NU2I 1LR8A 3TJQA 2QQCA 1SGYI 1CSOI 1MT1A 1SGRI 2GKTI 1HPTA 1AN1I 2KMPA 2JXDA 1Y1CA 3OVOA 3HH2C 1TIHA 3SEKC 1KMAA 1SGPI 1BUSA 1CGII 2N17A 2LEOA 1CE3A 2KMOA 1FYBA 2SGDI 1UVFA 1SGNI 1CGJI 1BMOA 4SGBI 2QQDA 2WCYA 2P6AC 1UVGA 1UUCA 4OVOA 1TBQR 1HJAI
chains in the Genus database with same CATH superfamily
1IY6A 2F3CI 1TUSA 2Y0MA 4AMLA 2KCXA 2CWGA 3B4VC 1Z7KB 2UVOA 2SGEI 1V1HA 5HI7A 1PCEA 1DS3I 2PQ8A 2SGPI 2ARPF 2QQEA 3UGIA 5FUWA 1M8CA 2ORWA 1TGSI 1DS2I 1PPFI 2RC4A 1SGQI 2JA1A 3OXGA 5FUYA 1N13A 1Y1BA 2NU3I 2L8EA 1YTPA 2J87A 3FSXA 5FUXA 2GKVA 2N71A 1HDLA 2KMQA 2OVOA 3TO7A 5CCLA 3SGQI 2B0UC 2QPOA 1TBRR 1CT4I 2E5RA 2OZUA 1IW4A 5E3RA 1CHOI 2M5XA 3RU0A 1M8BA 3OXLA 2BUSA 2NU0I 1WKXA 5FUVA 4WP4A 2JYYA 2KMRA 2ODDA 3CXLA 1R79A 3R5DA 1ULMA 1FAQA 3R5CA 5DAEA 5EX0A 2ELIA 1TBOA 2XRCA 2ORVA 1WTJA 3E2IA 4HGUA 1PTRA 1NUBA 1P9ZA 2B8TA 1ULNA 3QTLD 1Y8FA 5EX3A 3SGBI 1IY5A 1MJAA 1XA6A 3R5BA 1U5KA 3UOEA 1R0RI 2NU4I 5J8CA 2ENZA 2GVIA 1SGDI 3VDUA 2SGFI 2N1AB 2WVJA 4B6DA 4FKDA 2NU1I 3TO6A 2V53A 3VE5A 4E1PA 9WGAA 2JZMA 5JHWC 1V1IA 1OMUA 4MPIA 1WGCA 2ERWA 1YU6C 4UXJA 3OL0A 1LR9A 1TURA 2X52A 3MEKA 4UXHA 1H0ZA 1OMTA 1OYVI 1CT0I 1Z2IA 4GI3C 1HEVA 1PJUA 1CT2I 2CWHA 1LR7A 3UEJA 3KY9A 1OVOA 1NXUA 3E59A 1SGEI 2J9RA 4JCVE 4A24A 2N52A 4UXIA 1UHAA 5E3PA 2DB6A 2GKRI 5HQ8A 2L7XA 1TOTA 3TOBA 2K9HA 2ROWA 2UZ3A 4E1RA 1S20A 2VRWB 2SGQI 4L9MA 2NU2I 1X4SA 1K7TA 2X3TA 2QQ0A 1LR8A 1KBFA 3FSYA 2QQCA 3TJQA 7WGAA 1SGYI 1PTQA 1CSOI 2OU2A 1X74A 1MT1A 1TBNA 3UGLA 1SGRI 1K7UA 1MJBA 2GKTI 2CJSC 2V1CC 1HPTA 2W0TA 1AN1I 2E73A 5E3QA 3UFFA 2RIJA 3QWPA 5J8FA 2JW6A 2KMPA 1W3SA 2JXDA 2LB7A 2FNFX 2LUYA 1Y1CA 3BJIA 1FARA 1KBEA 1Q9BA 1XX6A 3OVOA 3UGDA 3HH2C 3GOXA 1TIHA 3SEKC 3QAHA 1SGPI 1KMAA 3FC3A 2GIVA 1VDDA 1BUSA 2YUUA 2YQPA 3R5AA 1FY7A 1CGII 1P9GA 3OXFA 2N17A 2LEOA 1WGTA 1CE3A 2KMOA 1FYBA 2CWFA 1ULKA 2DIPA 3TOAA 2A20A 2SGDI 1UVFA 2WGCA 3TO9A 1SGNI 1CGJI 1BMOA 4DNCA 1RFHA 4SGBI 1W4RA 2QQDA 2ENNA 2OD1A 2WCYA 2P6AC 1UVGA 2DKVA 1UUCA 2V1CA 5CCMA 1XBTA 3D00A 3UEYA 3PDNA 4OVOA 1MJ9A 1K7VA 1TBQR 1HJAI 3VDPA
chains in the Genus database with same CATH topology
1IY6A 2F3CI 1TUSA 2KCXA 3B4VC 1Z7KB 2SGEI 1V1HA 5HI7A 1PCEA 1DS3I 2SGPI 2ARPF 2QQEA 3UGIA 5FUWA 1M8CA 2ORWA 1TGSI 1DS2I 1PPFI 1SGQI 2JA1A 3OXGA 5FUYA 1N13A 1Y1BA 2NU3I 2L8EA 1YTPA 2J87A 5FUXA 2GKVA 2N71A 1HDLA 2KMQA 2OVOA 5CCLA 3SGQI 2B0UC 2QPOA 1TBRR 1CT4I 2E5RA 1IW4A 1CHOI 2M5XA 3RU0A 1M8BA 3OXLA 2BUSA 2NU0I 5FUVA 2JYYA 2KMRA 2ODDA 3CXLA 1R79A 1FAQA 5DAEA 5EX0A 2ELIA 1TBOA 2XRCA 2ORVA 3E2IA 4HGUA 1PTRA 1NUBA 2B8TA 3QTLD 1Y8FA 5EX3A 3SGBI 1IY5A 1XA6A 1U5KA 1R0RI 2NU4I 2ENZA 2GVIA 1SGDI 3VDUA 2SGFI 2N1AB 2WVJA 4B6DA 4FKDA 2NU1I 2V53A 3VE5A 4E1PA 2JZMA 5JHWC 1V1IA 1OMUA 4UXJA 2ERWA 5CCMA 1YU6C 3OL0A 1LR9A 1TURA 3MEKA 4UXHA 1H0ZA 1OMTA 1OYVI 1CT0I 4GI3C 1PJUA 1CT2I 1LR7A 3UEJA 3KY9A 1OVOA 3E59A 1SGEI 2J9RA 4JCVE 4A24A 2N52A 4UXIA 2DB6A 2GKRI 5HQ8A 2L7XA 1TOTA 2K9HA 2ROWA 2UZ3A 4E1RA 2VRWB 2SGQI 4L9MA 2NU2I 1X4SA 2QQ0A 1LR8A 1KBFA 3TJQA 2QQCA 1SGYI 1PTQA 1CSOI 1X74A 1MT1A 1TBNA 3UGLA 1SGRI 2GKTI 2CJSC 2V1CC 1HPTA 2W0TA 1AN1I 2E73A 3UFFA 3QWPA 2JW6A 2KMPA 1W3SA 2JXDA 2LUYA 2FNFX 1Y1CA 3BJIA 1FARA 1KBEA 1XX6A 3OVOA 3UGDA 3GOXA 3HH2C 1TIHA 3SEKC 1KMAA 1SGPI 3FC3A 1VDDA 1BUSA 2YUUA 2YQPA 1CGII 3OXFA 2N17A 2LEOA 1CE3A 2KMOA 1FYBA 2DIPA 2A20A 2SGDI 1UVFA 1SGNI 1CGJI 1BMOA 1RFHA 4SGBI 1W4RA 2QQDA 2ENNA 2OD1A 2WCYA 2P6AC 1UVGA 1UUCA 2V1CA 1XBTA 3D00A 3UEYA 3PDNA 4OVOA 1TBQR 1HJAI 3VDPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1IY6 A;  2F3C I;  1TUS A;  2KCX A;  3B4V C;  1Z7K B;  2SGE I;  1PCE A;  1DS3 I;  2SGP I;  2ARP F;  1M8C A;  1TGS I;  1DS2 I;  1PPF I;  1SGQ I;  1N13 A;  1Y1B A;  2NU3 I;  1YTP A;  2GKV A;  2N71 A;  1HDL A;  2KMQ A;  2OVO A;  3SGQ I;  2B0U C;  1TBR R;  1CT4 I;  1IW4 A;  1CHO I;  2M5X A;  1M8B A;  2BUS A;  2NU0 I;  2KMR A;  2JYY A;  5DAE A;  2XRC A;  4HGU A;  1NUB A;  3QTL D;  3SGB I;  1IY5 A;  1R0R I;  2NU4 I;  1SGD I;  2SGF I;  2NU1 I;  2V53 A;  2JZM A;  5JHW C;  1OMU A;  2ERW A;  1YU6 C;  1LR9 A;  1TUR A;  1H0Z A;  1OMT A;  1OYV I;  1CT0 I;  4GI3 C;  1PJU A;  1CT2 I;  1LR7 A;  1OVO A;  1SGE I;  2N52 A;  2GKR I;  2SGQ I;  2NU2 I;  1LR8 A;  3TJQ A;  2QQC A;  1SGY I;  1CSO I;  1MT1 A;  1SGR I;  2GKT I;  1HPT A;  1AN1 I;  2KMP A;  2JXD A;  1Y1C A;  3OVO A;  3HH2 C;  1TIH A;  3SEK C;  1KMA A;  1SGP I;  1BUS A;  1CGI I;  2N17 A;  2LEO A;  1CE3 A;  2KMO A;  1FYB A;  2SGD I;  1UVF A;  1SGN I;  1CGJ I;  1BMO A;  4SGB I;  2QQD A;  2WCY A;  2P6A C;  1UVG A;  1UUC A;  4OVO A;  1TBQ R;  1HJA I; 
#chains in the Genus database with same CATH topology
 1IY6 A;  2F3C I;  1TUS A;  2Y0M A;  4AML A;  2KCX A;  2CWG A;  3B4V C;  1Z7K B;  2UVO A;  2SGE I;  1V1H A;  5HI7 A;  1PCE A;  1DS3 I;  2PQ8 A;  2SGP I;  2ARP F;  2QQE A;  3UGI A;  5FUW A;  1M8C A;  2ORW A;  1TGS I;  1DS2 I;  1PPF I;  2RC4 A;  1SGQ I;  2JA1 A;  3OXG A;  5FUY A;  1N13 A;  1Y1B A;  2NU3 I;  2L8E A;  1YTP A;  2J87 A;  3FSX A;  5FUX A;  2GKV A;  2N71 A;  1HDL A;  2KMQ A;  2OVO A;  3TO7 A;  5CCL A;  3SGQ I;  2B0U C;  2QPO A;  1TBR R;  1CT4 I;  2E5R A;  2OZU A;  1IW4 A;  5E3R A;  1CHO I;  2M5X A;  3RU0 A;  1M8B A;  3OXL A;  2BUS A;  2NU0 I;  1WKX A;  5FUV A;  4WP4 A;  2JYY A;  2KMR A;  2ODD A;  3CXL A;  1R79 A;  3R5D A;  1ULM A;  1FAQ A;  3R5C A;  5DAE A;  5EX0 A;  2ELI A;  1TBO A;  2XRC A;  2ORV A;  1WTJ A;  3E2I A;  4HGU A;  1PTR A;  1NUB A;  1P9Z A;  2B8T A;  1ULN A;  3QTL D;  1Y8F A;  5EX3 A;  3SGB I;  1IY5 A;  1MJA A;  1XA6 A;  3R5B A;  1U5K A;  3UOE A;  1R0R I;  2NU4 I;  5J8C A;  2ENZ A;  2GVI A;  1SGD I;  3VDU A;  2SGF I;  2N1A B;  2WVJ A;  4B6D A;  4FKD A;  2NU1 I;  3TO6 A;  2V53 A;  3VE5 A;  4E1P A;  9WGA A;  2JZM A;  5JHW C;  1V1I A;  1OMU A;  4MPI A;  1WGC A;  2ERW A;  1YU6 C;  4UXJ A;  3OL0 A;  1LR9 A;  1TUR A;  2X52 A;  3MEK A;  4UXH A;  1H0Z A;  1OMT A;  1OYV I;  1CT0 I;  1Z2I A;  4GI3 C;  1HEV A;  1PJU A;  1CT2 I;  2CWH A;  1LR7 A;  3UEJ A;  3KY9 A;  1OVO A;  1NXU A;  3E59 A;  1SGE I;  2J9R A;  4JCV E;  4A24 A;  2N52 A;  4UXI A;  1UHA A;  5E3P A;  2DB6 A;  2GKR I;  5HQ8 A;  2L7X A;  1TOT A;  3TOB A;  2K9H A;  2ROW A;  2UZ3 A;  4E1R A;  1S20 A;  2VRW B;  2SGQ I;  4L9M A;  2NU2 I;  1X4S A;  1K7T A;  2X3T A;  2QQ0 A;  1LR8 A;  1KBF A;  3FSY A;  2QQC A;  3TJQ A;  7WGA A;  1SGY I;  1PTQ A;  1CSO I;  2OU2 A;  1X74 A;  1MT1 A;  1TBN A;  3UGL A;  1SGR I;  1K7U A;  1MJB A;  2GKT I;  2CJS C;  2V1C C;  1HPT A;  2W0T A;  1AN1 I;  2E73 A;  5E3Q A;  3UFF A;  2RIJ A;  3QWP A;  5J8F A;  2JW6 A;  2KMP A;  1W3S A;  2JXD A;  2LB7 A;  2FNF X;  2LUY A;  1Y1C A;  3BJI A;  1FAR A;  1KBE A;  1Q9B A;  1XX6 A;  3OVO A;  3UGD A;  3HH2 C;  3GOX A;  1TIH A;  3SEK C;  3QAH A;  1SGP I;  1KMA A;  3FC3 A;  2GIV A;  1VDD A;  1BUS A;  2YUU A;  2YQP A;  3R5A A;  1FY7 A;  1CGI I;  1P9G A;  3OXF A;  2N17 A;  2LEO A;  1WGT A;  1CE3 A;  2KMO A;  1FYB A;  2CWF A;  1ULK A;  2DIP A;  3TOA A;  2A20 A;  2SGD I;  1UVF A;  2WGC A;  3TO9 A;  1SGN I;  1CGJ I;  1BMO A;  4DNC A;  1RFH A;  4SGB I;  1W4R A;  2QQD A;  2ENN A;  2OD1 A;  2WCY A;  2P6A C;  1UVG A;  2DKV A;  1UUC A;  2V1C A;  5CCM A;  1XBT A;  3D00 A;  3UEY A;  3PDN A;  4OVO A;  1MJ9 A;  1K7V A;  1TBQ R;  1HJA I;  3VDP A; 
#chains in the Genus database with same CATH homology
 1IY6 A;  2F3C I;  1TUS A;  2KCX A;  3B4V C;  1Z7K B;  2SGE I;  1V1H A;  5HI7 A;  1PCE A;  1DS3 I;  2SGP I;  2ARP F;  2QQE A;  3UGI A;  5FUW A;  1M8C A;  2ORW A;  1TGS I;  1DS2 I;  1PPF I;  1SGQ I;  2JA1 A;  3OXG A;  5FUY A;  1N13 A;  1Y1B A;  2NU3 I;  2L8E A;  1YTP A;  2J87 A;  5FUX A;  2GKV A;  2N71 A;  1HDL A;  2KMQ A;  2OVO A;  5CCL A;  3SGQ I;  2B0U C;  2QPO A;  1TBR R;  1CT4 I;  2E5R A;  1IW4 A;  1CHO I;  2M5X A;  3RU0 A;  1M8B A;  3OXL A;  2BUS A;  2NU0 I;  5FUV A;  2JYY A;  2KMR A;  2ODD A;  3CXL A;  1R79 A;  1FAQ A;  5DAE A;  5EX0 A;  2ELI A;  1TBO A;  2XRC A;  2ORV A;  3E2I A;  4HGU A;  1PTR A;  1NUB A;  2B8T A;  3QTL D;  1Y8F A;  5EX3 A;  3SGB I;  1IY5 A;  1XA6 A;  1U5K A;  1R0R I;  2NU4 I;  2ENZ A;  2GVI A;  1SGD I;  3VDU A;  2SGF I;  2N1A B;  2WVJ A;  4B6D A;  4FKD A;  2NU1 I;  2V53 A;  3VE5 A;  4E1P A;  2JZM A;  5JHW C;  1V1I A;  1OMU A;  4UXJ A;  2ERW A;  5CCM A;  1YU6 C;  3OL0 A;  1LR9 A;  1TUR A;  3MEK A;  4UXH A;  1H0Z A;  1OMT A;  1OYV I;  1CT0 I;  4GI3 C;  1PJU A;  1CT2 I;  1LR7 A;  3UEJ A;  3KY9 A;  1OVO A;  3E59 A;  1SGE I;  2J9R A;  4JCV E;  4A24 A;  2N52 A;  4UXI A;  2DB6 A;  2GKR I;  5HQ8 A;  2L7X A;  1TOT A;  2K9H A;  2ROW A;  2UZ3 A;  4E1R A;  2VRW B;  2SGQ I;  4L9M A;  2NU2 I;  1X4S A;  2QQ0 A;  1LR8 A;  1KBF A;  3TJQ A;  2QQC A;  1SGY I;  1PTQ A;  1CSO I;  1X74 A;  1MT1 A;  1TBN A;  3UGL A;  1SGR I;  2GKT I;  2CJS C;  2V1C C;  1HPT A;  2W0T A;  1AN1 I;  2E73 A;  3UFF A;  3QWP A;  2JW6 A;  2KMP A;  1W3S A;  2JXD A;  2LUY A;  2FNF X;  1Y1C A;  3BJI A;  1FAR A;  1KBE A;  1XX6 A;  3OVO A;  3UGD A;  3GOX A;  3HH2 C;  1TIH A;  3SEK C;  1KMA A;  1SGP I;  3FC3 A;  1VDD A;  1BUS A;  2YUU A;  2YQP A;  1CGI I;  3OXF A;  2N17 A;  2LEO A;  1CE3 A;  2KMO A;  1FYB A;  2DIP A;  2A20 A;  2SGD I;  1UVF A;  1SGN I;  1CGJ I;  1BMO A;  1RFH A;  4SGB I;  1W4R A;  2QQD A;  2ENN A;  2OD1 A;  2WCY A;  2P6A C;  1UVG A;  1UUC A;  2V1C A;  1XBT A;  3D00 A;  3UEY A;  3PDN A;  4OVO A;  1TBQ R;  1HJA I;  3VDP A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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