1PPFI

X-ray crystal structure of the complex of human leukocyte elastase (pmn elastase) and the third domain of the turkey ovomucoid inhibitor
Total Genus 13
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
13
sequence length
56
structure length
56
Chain Sequence
b'LAAVSVDCSEYPKPACTLEYRPLCGSDNKTYGNKCNFCNAVVESNGTLTLSHFGKC'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords HUMAN LEUKOCYTE ELASTASE
publication title X-ray crystal structure of the complex of human leukocyte elastase (PMN elastase) and the third domain of the turkey ovomucoid inhibitor.
pubmed rcsb
source organism Homo sapiens
molecule tags Hydrolase/hydrolase inhibitor
total genus 13
structure length 56
sequence length 56
ec nomenclature
pdb deposition date 1991-10-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
I PF00050 Kazal_1 Kazal-type serine protease inhibitor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.60.30 Alpha Beta 2-Layer Sandwich Wheat Germ Agglutinin (Isolectin 2); domain 1 Wheat Germ Agglutinin (Isolectin 2); domain 1 1ppfI00
1SGRI 1SGPI 1LR8A 1CT0I 4SGBI 2OVOA 2SGFI 2JYYA 1R0RI 1Y1BA 4GI3C 2KCXA 5DAEA 2N71A 1BMOA 2QQDA 1YTPA 2GKTI 2NU0I 3HH2C 1TUSA 1TURA 4HGUA 1M8CA 2NU3I 1LR7A 1CT4I 1SGEI 2GKRI 1NUBA 2WCYA 2KMRA 2B0UC 2GKVA 1HJAI 1OMUA 2NU4I 2V53A 3OVOA 3SGBI 2XRCA 1IY6A 3QTLD 5JHWC 1DS3I 1PCEA 1FYBA 1CE3A 1CGJI 1UVFA 1TIHA 1BUSA 1KMAA 1OYVI 2N17A 3B4VC 2KMQA 2SGEI 4OVOA 2NU1I 2ARPF 2BUSA 1AN1I 1YU6C 1CSOI 1CT2I 1IY5A 2LEOA 2P6AC 2SGPI 1SGQI 1IW4A 1HPTA 2F3CI 1LR9A 2QQCA 1UVGA 1TBRR 2N52A 3SEKC 1Y1CA 1MT1A 3SGQI 1Z7KB 1OVOA 1SGDI 1SGNI 2KMOA 2NU2I 1M8BA 1TBQR 1H0ZA 1TGSI 1UUCA 3TJQA 2JZMA 2SGQI 1OMTA 2SGDI 1CHOI 1CGII 1PPFI 2KMPA 1PJUA 1HDLA 1DS2I 1SGYI 2JXDA 2ERWA 1N13A 2M5XA
chains in the Genus database with same CATH superfamily
1P9ZA 2ENZA 2UZ3A 1SGRI 2J87A 2FNFX 1SGPI 2GIVA 1LR8A 1CT0I 2N1AB 4SGBI 3R5BA 1FAQA 2OVOA 1ULNA 3R5AA 2SGFI 5EX0A 2JYYA 1R0RI 1XX6A 1Y1BA 1KBFA 1K7TA 2L8EA 4GI3C 2KCXA 5DAEA 1ULKA 2N71A 5E3QA 1R79A 1BMOA 4UXHA 1MJBA 2RIJA 1PTQA 1K7UA 3KY9A 1U5KA 2YUUA 3UGLA 3GOXA 2CWGA 2CWFA 2QQDA 2ORWA 2X52A 1YTPA 2GKTI 2JA1A 1S20A 2NU0I 1TUSA 2OZUA 1TURA 2QQEA 3HH2C 2WGCA 2WVJA 1Y8FA 3RU0A 4HGUA 1M8CA 2NU3I 1LR7A 1CT4I 1SGEI 2GKRI 1NUBA 2WCYA 2KMRA 5HI7A 3UFFA 2X3TA 4E1PA 2B0UC 2E5RA 2GKVA 1ULMA 2B8TA 3TO6A 4AMLA 1HJAI 1OMUA 5FUXA 3TOAA 1W4RA 1XA6A 1K7VA 1Q9BA 3UOEA 2NU4I 3CXLA 4E1RA 2ELIA 1KBEA 5FUVA 7WGAA 2V53A 3OVOA 3PDNA 5EX3A 3TOBA 4A24A 1HEVA 3SGBI 2XRCA 2DIPA 2ENNA 2VRWB 4UXIA 2UVOA 1RFHA 1IY6A 2L7XA 3QTLD 5JHWC 1DS3I 1PCEA 1FYBA 1CE3A 4WP4A 1CGJI 2V1CA 3R5CA 1UVFA 1UHAA 2LUYA 2Y0MA 1TIHA 4UXJA 3FC3A 2GVIA 2YQPA 3QWPA 1BUSA 4FKDA 3VDPA 1KMAA 3E59A 3UEYA 1OYVI 2CJSC 1WGCA 2N17A 2DKVA 1PTRA 2K9HA 1MJ9A 2JW6A 3B4VC 3UEJA 2KMQA 1FY7A 2SGEI 1X74A 3FSXA 4OVOA 2NU1I 2ARPF 2BUSA 1AN1I 5CCMA 1VDDA 1YU6C 1CSOI 3VE5A 1CT2I 3FSYA 1TOTA 3UGIA 1IY5A 3OL0A 1WGTA 1V1HA 3MEKA 4B6DA 3TO9A 3QAHA 2LEOA 2P6AC 1XBTA 2SGPI 3VDUA 1SGQI 1TBOA 3OXFA 1FARA 5CCLA 2RC4A 1IW4A 5J8CA 3D00A 1HPTA 3TO7A 2F3CI 2QPOA 2ROWA 1LR9A 2QQCA 5E3RA 1UVGA 1WKXA 1TBRR 2J9RA 2N52A 4L9MA 3SEKC 1X4SA 4MPIA 2E73A 2ODDA 4JCVE 1MJAA 9WGAA 1Y1CA 5J8FA 1MT1A 3SGQI 1NXUA 1Z7KB 1Z2IA 2OU2A 1W3SA 3BJIA 1OVOA 1SGDI 1SGNI 2KMOA 2DB6A 1M8BA 2A20A 2NU2I 4DNCA 1TBQR 2QQ0A 2ORVA 1TBNA 2CWHA 2V1CC 1H0ZA 2W0TA 2LB7A 1TGSI 1UUCA 1P9GA 3TJQA 2JZMA 2SGQI 1OMTA 2SGDI 3OXGA 3R5DA 1CHOI 1CGII 1PPFI 2KMPA 2OD1A 1V1IA 3OXLA 5HQ8A 5FUYA 5FUWA 3UGDA 3E2IA 1PJUA 1WTJA 1HDLA 1DS2I 1SGYI 2JXDA 5E3PA 2ERWA 2PQ8A 1N13A 2M5XA
chains in the Genus database with same CATH topology
2ENZA 2UZ3A 1SGRI 2J87A 2FNFX 1SGPI 1LR8A 1CT0I 2N1AB 4SGBI 1FAQA 2OVOA 5EX0A 2SGFI 2JYYA 1R0RI 1XX6A 1Y1BA 1KBFA 2L8EA 4GI3C 2KCXA 5DAEA 2N71A 1R79A 1BMOA 4UXHA 1PTQA 3KY9A 3UGLA 1U5KA 2YUUA 3GOXA 2QQDA 2ORWA 1YTPA 2GKTI 2JA1A 2NU0I 3HH2C 1TUSA 2QQEA 1TURA 2WVJA 1Y8FA 3RU0A 4HGUA 1M8CA 2NU3I 1LR7A 1CT4I 1SGEI 2GKRI 1NUBA 2WCYA 2KMRA 5HI7A 3UFFA 4E1PA 2B0UC 2E5RA 2GKVA 2B8TA 1HJAI 1OMUA 5FUXA 1W4RA 1XA6A 2NU4I 3CXLA 4E1RA 2ELIA 1KBEA 5FUVA 2V53A 3OVOA 3PDNA 5EX3A 4A24A 3SGBI 2XRCA 2DIPA 2ENNA 2VRWB 4UXIA 1RFHA 1IY6A 2L7XA 3QTLD 5JHWC 1DS3I 1PCEA 1FYBA 1CE3A 1CGJI 2V1CA 1UVFA 2LUYA 4UXJA 3FC3A 1TIHA 2GVIA 2YQPA 3QWPA 1BUSA 4FKDA 3VDPA 1KMAA 3E59A 3UEYA 1OYVI 2CJSC 2N17A 1PTRA 2K9HA 2JW6A 3B4VC 3UEJA 2KMQA 2SGEI 1X74A 4OVOA 2NU1I 2ARPF 2BUSA 1AN1I 5CCMA 1VDDA 1YU6C 1CSOI 3VE5A 1CT2I 3UGIA 1TOTA 1IY5A 3OL0A 1V1HA 3MEKA 4B6DA 2LEOA 2P6AC 1XBTA 2SGPI 3VDUA 1SGQI 1TBOA 3OXFA 1FARA 5CCLA 1IW4A 3D00A 1HPTA 2F3CI 2QPOA 2ROWA 1LR9A 2QQCA 1UVGA 2J9RA 1TBRR 2N52A 3SEKC 4L9MA 1X4SA 2E73A 2ODDA 4JCVE 1Y1CA 1MT1A 3SGQI 1Z7KB 1W3SA 3BJIA 1OVOA 1SGDI 1SGNI 2KMOA 2DB6A 1M8BA 2A20A 2NU2I 1TBQR 2QQ0A 2ORVA 1TBNA 2V1CC 1H0ZA 2W0TA 1TGSI 1UUCA 3TJQA 2JZMA 2SGQI 1OMTA 2SGDI 3OXGA 1CHOI 1CGII 1PPFI 2KMPA 2OD1A 1V1IA 3OXLA 5HQ8A 5FUYA 5FUWA 3UGDA 3E2IA 1PJUA 1HDLA 1DS2I 1SGYI 2JXDA 2ERWA 1N13A 2M5XA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1SGR I;  1SGP I;  1LR8 A;  1CT0 I;  4SGB I;  2OVO A;  2SGF I;  2JYY A;  1R0R I;  1Y1B A;  4GI3 C;  2KCX A;  5DAE A;  2N71 A;  1BMO A;  2QQD A;  1YTP A;  2GKT I;  2NU0 I;  3HH2 C;  1TUS A;  1TUR A;  4HGU A;  1M8C A;  2NU3 I;  1LR7 A;  1CT4 I;  1SGE I;  2GKR I;  1NUB A;  2WCY A;  2KMR A;  2B0U C;  2GKV A;  1HJA I;  1OMU A;  2NU4 I;  2V53 A;  3OVO A;  3SGB I;  2XRC A;  1IY6 A;  3QTL D;  5JHW C;  1DS3 I;  1PCE A;  1FYB A;  1CE3 A;  1CGJ I;  1UVF A;  1TIH A;  1BUS A;  1KMA A;  1OYV I;  2N17 A;  3B4V C;  2KMQ A;  2SGE I;  4OVO A;  2NU1 I;  2ARP F;  2BUS A;  1AN1 I;  1YU6 C;  1CSO I;  1CT2 I;  1IY5 A;  2LEO A;  2P6A C;  2SGP I;  1SGQ I;  1IW4 A;  1HPT A;  2F3C I;  1LR9 A;  2QQC A;  1UVG A;  1TBR R;  2N52 A;  3SEK C;  1Y1C A;  1MT1 A;  3SGQ I;  1Z7K B;  1OVO A;  1SGD I;  1SGN I;  2KMO A;  2NU2 I;  1M8B A;  1TBQ R;  1H0Z A;  1TGS I;  1UUC A;  3TJQ A;  2JZM A;  2SGQ I;  1OMT A;  2SGD I;  1CHO I;  1CGI I;  1PPF I;  2KMP A;  1PJU A;  1HDL A;  1DS2 I;  1SGY I;  2JXD A;  2ERW A;  1N13 A;  2M5X A; 
#chains in the Genus database with same CATH topology
 1P9Z A;  2ENZ A;  2UZ3 A;  1SGR I;  2J87 A;  2FNF X;  1SGP I;  2GIV A;  1LR8 A;  1CT0 I;  2N1A B;  4SGB I;  3R5B A;  1FAQ A;  2OVO A;  1ULN A;  3R5A A;  2SGF I;  5EX0 A;  2JYY A;  1R0R I;  1XX6 A;  1Y1B A;  1KBF A;  1K7T A;  2L8E A;  4GI3 C;  2KCX A;  5DAE A;  1ULK A;  2N71 A;  5E3Q A;  1R79 A;  1BMO A;  4UXH A;  1MJB A;  2RIJ A;  1PTQ A;  1K7U A;  3KY9 A;  1U5K A;  2YUU A;  3UGL A;  3GOX A;  2CWG A;  2CWF A;  2QQD A;  2ORW A;  2X52 A;  1YTP A;  2GKT I;  2JA1 A;  1S20 A;  2NU0 I;  1TUS A;  2OZU A;  1TUR A;  2QQE A;  3HH2 C;  2WGC A;  2WVJ A;  1Y8F A;  3RU0 A;  4HGU A;  1M8C A;  2NU3 I;  1LR7 A;  1CT4 I;  1SGE I;  2GKR I;  1NUB A;  2WCY A;  2KMR A;  5HI7 A;  3UFF A;  2X3T A;  4E1P A;  2B0U C;  2E5R A;  2GKV A;  1ULM A;  2B8T A;  3TO6 A;  4AML A;  1HJA I;  1OMU A;  5FUX A;  3TOA A;  1W4R A;  1XA6 A;  1K7V A;  1Q9B A;  3UOE A;  2NU4 I;  3CXL A;  4E1R A;  2ELI A;  1KBE A;  5FUV A;  7WGA A;  2V53 A;  3OVO A;  3PDN A;  5EX3 A;  3TOB A;  4A24 A;  1HEV A;  3SGB I;  2XRC A;  2DIP A;  2ENN A;  2VRW B;  4UXI A;  2UVO A;  1RFH A;  1IY6 A;  2L7X A;  3QTL D;  5JHW C;  1DS3 I;  1PCE A;  1FYB A;  1CE3 A;  4WP4 A;  1CGJ I;  2V1C A;  3R5C A;  1UVF A;  1UHA A;  2LUY A;  2Y0M A;  1TIH A;  4UXJ A;  3FC3 A;  2GVI A;  2YQP A;  3QWP A;  1BUS A;  4FKD A;  3VDP A;  1KMA A;  3E59 A;  3UEY A;  1OYV I;  2CJS C;  1WGC A;  2N17 A;  2DKV A;  1PTR A;  2K9H A;  1MJ9 A;  2JW6 A;  3B4V C;  3UEJ A;  2KMQ A;  1FY7 A;  2SGE I;  1X74 A;  3FSX A;  4OVO A;  2NU1 I;  2ARP F;  2BUS A;  1AN1 I;  5CCM A;  1VDD A;  1YU6 C;  1CSO I;  3VE5 A;  1CT2 I;  3FSY A;  1TOT A;  3UGI A;  1IY5 A;  3OL0 A;  1WGT A;  1V1H A;  3MEK A;  4B6D A;  3TO9 A;  3QAH A;  2LEO A;  2P6A C;  1XBT A;  2SGP I;  3VDU A;  1SGQ I;  1TBO A;  3OXF A;  1FAR A;  5CCL A;  2RC4 A;  1IW4 A;  5J8C A;  3D00 A;  1HPT A;  3TO7 A;  2F3C I;  2QPO A;  2ROW A;  1LR9 A;  2QQC A;  5E3R A;  1UVG A;  1WKX A;  1TBR R;  2J9R A;  2N52 A;  4L9M A;  3SEK C;  1X4S A;  4MPI A;  2E73 A;  2ODD A;  4JCV E;  1MJA A;  9WGA A;  1Y1C A;  5J8F A;  1MT1 A;  3SGQ I;  1NXU A;  1Z7K B;  1Z2I A;  2OU2 A;  1W3S A;  3BJI A;  1OVO A;  1SGD I;  1SGN I;  2KMO A;  2DB6 A;  1M8B A;  2A20 A;  2NU2 I;  4DNC A;  1TBQ R;  2QQ0 A;  2ORV A;  1TBN A;  2CWH A;  2V1C C;  1H0Z A;  2W0T A;  2LB7 A;  1TGS I;  1UUC A;  1P9G A;  3TJQ A;  2JZM A;  2SGQ I;  1OMT A;  2SGD I;  3OXG A;  3R5D A;  1CHO I;  1CGI I;  1PPF I;  2KMP A;  2OD1 A;  1V1I A;  3OXL A;  5HQ8 A;  5FUY A;  5FUW A;  3UGD A;  3E2I A;  1PJU A;  1WTJ A;  1HDL A;  1DS2 I;  1SGY I;  2JXD A;  5E3P A;  2ERW A;  2PQ8 A;  1N13 A;  2M5X A; 
#chains in the Genus database with same CATH homology
 2ENZ A;  2UZ3 A;  1SGR I;  2J87 A;  2FNF X;  1SGP I;  1LR8 A;  1CT0 I;  2N1A B;  4SGB I;  1FAQ A;  2OVO A;  5EX0 A;  2SGF I;  2JYY A;  1R0R I;  1XX6 A;  1Y1B A;  1KBF A;  2L8E A;  4GI3 C;  2KCX A;  5DAE A;  2N71 A;  1R79 A;  1BMO A;  4UXH A;  1PTQ A;  3KY9 A;  3UGL A;  1U5K A;  2YUU A;  3GOX A;  2QQD A;  2ORW A;  1YTP A;  2GKT I;  2JA1 A;  2NU0 I;  3HH2 C;  1TUS A;  2QQE A;  1TUR A;  2WVJ A;  1Y8F A;  3RU0 A;  4HGU A;  1M8C A;  2NU3 I;  1LR7 A;  1CT4 I;  1SGE I;  2GKR I;  1NUB A;  2WCY A;  2KMR A;  5HI7 A;  3UFF A;  4E1P A;  2B0U C;  2E5R A;  2GKV A;  2B8T A;  1HJA I;  1OMU A;  5FUX A;  1W4R A;  1XA6 A;  2NU4 I;  3CXL A;  4E1R A;  2ELI A;  1KBE A;  5FUV A;  2V53 A;  3OVO A;  3PDN A;  5EX3 A;  4A24 A;  3SGB I;  2XRC A;  2DIP A;  2ENN A;  2VRW B;  4UXI A;  1RFH A;  1IY6 A;  2L7X A;  3QTL D;  5JHW C;  1DS3 I;  1PCE A;  1FYB A;  1CE3 A;  1CGJ I;  2V1C A;  1UVF A;  2LUY A;  4UXJ A;  3FC3 A;  1TIH A;  2GVI A;  2YQP A;  3QWP A;  1BUS A;  4FKD A;  3VDP A;  1KMA A;  3E59 A;  3UEY A;  1OYV I;  2CJS C;  2N17 A;  1PTR A;  2K9H A;  2JW6 A;  3B4V C;  3UEJ A;  2KMQ A;  2SGE I;  1X74 A;  4OVO A;  2NU1 I;  2ARP F;  2BUS A;  1AN1 I;  5CCM A;  1VDD A;  1YU6 C;  1CSO I;  3VE5 A;  1CT2 I;  3UGI A;  1TOT A;  1IY5 A;  3OL0 A;  1V1H A;  3MEK A;  4B6D A;  2LEO A;  2P6A C;  1XBT A;  2SGP I;  3VDU A;  1SGQ I;  1TBO A;  3OXF A;  1FAR A;  5CCL A;  1IW4 A;  3D00 A;  1HPT A;  2F3C I;  2QPO A;  2ROW A;  1LR9 A;  2QQC A;  1UVG A;  2J9R A;  1TBR R;  2N52 A;  3SEK C;  4L9M A;  1X4S A;  2E73 A;  2ODD A;  4JCV E;  1Y1C A;  1MT1 A;  3SGQ I;  1Z7K B;  1W3S A;  3BJI A;  1OVO A;  1SGD I;  1SGN I;  2KMO A;  2DB6 A;  1M8B A;  2A20 A;  2NU2 I;  1TBQ R;  2QQ0 A;  2ORV A;  1TBN A;  2V1C C;  1H0Z A;  2W0T A;  1TGS I;  1UUC A;  3TJQ A;  2JZM A;  2SGQ I;  1OMT A;  2SGD I;  3OXG A;  1CHO I;  1CGI I;  1PPF I;  2KMP A;  2OD1 A;  1V1I A;  3OXL A;  5HQ8 A;  5FUY A;  5FUW A;  3UGD A;  3E2I A;  1PJU A;  1HDL A;  1DS2 I;  1SGY I;  2JXD A;  2ERW A;  1N13 A;  2M5X A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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