1PPFI

X-ray crystal structure of the complex of human leukocyte elastase (pmn elastase) and the third domain of the turkey ovomucoid inhibitor
Total Genus 13
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
13
sequence length
56
structure length
56
Chain Sequence
LAAVSVDCSEYPKPACTLEYRPLCGSDNKTYGNKCNFCNAVVESNGTLTLSHFGKC
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords HUMAN LEUKOCYTE ELASTASE
publication title X-ray crystal structure of the complex of human leukocyte elastase (PMN elastase) and the third domain of the turkey ovomucoid inhibitor.
pubmed rcsb
source organism Homo sapiens
molecule tags Hydrolase/hydrolase inhibitor
total genus 13
structure length 56
sequence length 56
ec nomenclature
pdb deposition date 1991-10-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
I PF00050 Kazal_1 Kazal-type serine protease inhibitor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.60.30 Alpha Beta 2-Layer Sandwich Wheat Germ Agglutinin (Isolectin 2); domain 1 Wheat Germ Agglutinin (Isolectin 2); domain 1 1ppfI00
2QQDA 3QTLD 2GKTI 1DS3I 2KCXA 1LR7A 1UVGA 2SGDI 1SGNI 2SGPI 2NU3I 2BUSA 2LEOA 1IY5A 2KMRA 1TBQR 5DAEA 1BMOA 1MT1A 1KMAA 1CHOI 2B0UC 1YU6C 4SGBI 1TURA 2P6AC 2NU2I 1CT4I 1TGSI 1FYBA 1M8BA 2F3CI 2SGEI 3SGBI 1OVOA 1UVFA 1N13A 2KMOA 2KMPA 2XRCA 1CT2I 2ERWA 3TJQA 1PPFI 1SGYI 2KMQA 1TIHA 1R0RI 1PJUA 1DS2I 1UUCA 1NUBA 1CGII 2N17A 3SEKC 1AN1I 1CE3A 1CT0I 1SGQI 2V53A 1TUSA 2JXDA 1PCEA 2SGQI 1Z7KB 2M5XA 2SGFI 1TBRR 1LR8A 1LR9A 2N71A 1HPTA 4HGUA 5JHWC 1OMTA 2N52A 1SGEI 3SGQI 2NU4I 1BUSA 1HDLA 2OVOA 1H0ZA 1Y1CA 1HJAI 1CGJI 4GI3C 1OYVI 2GKVA 1IY6A 1SGPI 1Y1BA 2JYYA 1YTPA 1SGDI 4OVOA 2GKRI 1CSOI 1SGRI 2QQCA 1IW4A 3HH2C 3B4VC 3OVOA 1M8CA 2ARPF 2JZMA 2WCYA 2NU0I 2NU1I 1OMUA
chains in the Genus database with same CATH superfamily
2DKVA 2QQDA 1R79A 5HI7A 3QTLD 3UGLA 2GKTI 3FC3A 1DS3I 2KCXA 3R5AA 1Q9BA 4DNCA 2ENNA 1LR7A 1UVGA 3UEYA 1TOTA 1SGNI 2SGDI 2SGPI 2NU3I 3TOAA 5J8CA 3VDUA 5FUWA 1P9GA 2BUSA 3OXGA 3UGIA 2LEOA 3CXLA 1IY5A 2KMRA 1ULNA 1TBQR 3FSYA 1S20A 2VRWB 2QPOA 4AMLA 2ROWA 5DAEA 7WGAA 1K7TA 1FAQA 1VDDA 1X74A 2WGCA 2E5RA 3QAHA 3TO6A 1BMOA 1MT1A 2ENZA 2NU0I 3UEJA 1KMAA 2ORWA 1CHOI 5EX0A 3E2IA 2B0UC 4UXJA 1PTRA 3R5BA 1YU6C 4SGBI 9WGAA 2JA1A 5E3PA 4JCVE 1TURA 2OZUA 2ELIA 2NU2I 1CT4I 1TGSI 2DIPA 2LB7A 2P6AC 1MJAA 1V1IA 3VE5A 1M8BA 2E73A 2V1CC 2RIJA 2X52A 2F3CI 1Z2IA 3D00A 2SGEI 2OD1A 1NXUA 3OXFA 3SGBI 1OVOA 2PQ8A 1UVFA 2J87A 1MJBA 1V1HA 1N13A 5CCLA 2KMOA 1K7VA 2KMPA 2JW6A 2XRCA 1CT2I 2ERWA 2W0TA 3TJQA 4B6DA 1PPFI 1SGYI 2KMQA 1MJ9A 1TIHA 1TBNA 1R0RI 1WKXA 2CJSC 2Y0MA 1PJUA 1DS2I 1FYBA 5E3RA 2A20A 1UUCA 1NUBA 2QQEA 1CGII 2B8TA 2N17A 4MPIA 4WP4A 3SEKC 1AN1I 1CE3A 5FUXA 4L9MA 1CT0I 1SGQI 2V53A 1Y8FA 1KBFA 1X4SA 1HEVA 5HQ8A 2ODDA 1TUSA 4A24A 2JXDA 2QQ0A 1PCEA 3PDNA 1KBEA 5E3QA 3R5DA 2SGQI 1TBOA 1Z7KB 1U5KA 2M5XA 1FARA 1ULKA 2OU2A 1XA6A 2SGFI 2FNFX 3QWPA 1TBRR 1XBTA 1LR8A 3FSXA 5EX3A 1WTJA 3UOEA 1LR9A 2L7XA 3BJIA 2N71A 1HPTA 4HGUA 5JHWC 1OMTA 2GIVA 2N52A 3TO9A 3MEKA 1SGEI 3KY9A 3SGQI 4E1RA 2LUYA 2NU4I 1P9ZA 1BUSA 2J9RA 1HDLA 3E59A 3OL0A 5J8FA 2DB6A 5CCMA 2OVOA 1H0ZA 1Y1CA 2K9HA 2WVJA 4FKDA 5FUYA 1HJAI 1RFHA 1K7UA 3OXLA 1CGJI 4GI3C 1WGTA 1OYVI 2GVIA 2UVOA 2X3TA 2GKVA 2YQPA 3TO7A 1FY7A 3UGDA 2L8EA 1W4RA 1IY6A 1SGPI 1Y1BA 2CWHA 2JYYA 1YTPA 2N1AB 1SGDI 4OVOA 4E1PA 3R5CA 1UHAA 2GKRI 1CSOI 1SGRI 1WGCA 2UZ3A 5FUVA 2QQCA 1ULMA 1IW4A 3HH2C 4UXIA 2YUUA 3RU0A 3B4VC 3TOBA 2ORVA 2CWGA 3OVOA 1M8CA 1XX6A 1PTQA 2V1CA 3UFFA 3VDPA 2ARPF 2JZMA 2RC4A 3GOXA 4UXHA 2WCYA 1W3SA 2NU1I 1OMUA 2CWFA
chains in the Genus database with same CATH topology
2QQDA 5HI7A 1R79A 3QTLD 3UGLA 2GKTI 3FC3A 1DS3I 2KCXA 2ENNA 1LR7A 1UVGA 3UEYA 1TOTA 1SGNI 2SGDI 2SGPI 2NU3I 3VDUA 5FUWA 2BUSA 3OXGA 3UGIA 2LEOA 3CXLA 1IY5A 2KMRA 1TBQR 2VRWB 2ROWA 5DAEA 1FAQA 1VDDA 1X74A 2E5RA 1BMOA 1MT1A 2ENZA 2NU0I 3UEJA 1KMAA 2ORWA 1CHOI 5EX0A 3E2IA 2B0UC 4UXJA 1PTRA 1YU6C 4SGBI 2JA1A 1KBFA 4JCVE 1TURA 2P6AC 2ELIA 2NU2I 1CT4I 1TGSI 2DIPA 2QPOA 3VE5A 1V1IA 1FYBA 1M8BA 2E73A 2V1CC 2F3CI 3D00A 2SGEI 2OD1A 3OXFA 3SGBI 1OVOA 1UVFA 2J87A 1V1HA 1N13A 5CCLA 2KMOA 2KMPA 2JW6A 2XRCA 1CT2I 2ERWA 2W0TA 3TJQA 4B6DA 1PPFI 1SGYI 2KMQA 1TIHA 1TBNA 1R0RI 2CJSC 1PJUA 1DS2I 2A20A 1UUCA 1NUBA 2QQEA 1CGII 2B8TA 2N17A 3SEKC 1AN1I 1CE3A 5FUXA 4L9MA 1CT0I 1SGQI 2V53A 1Y8FA 1X4SA 5HQ8A 2ODDA 1TUSA 4A24A 2JXDA 2QQ0A 1PCEA 3PDNA 1KBEA 2SGQI 1TBOA 1Z7KB 1U5KA 2M5XA 1FARA 3QWPA 3GOXA 1XA6A 2SGFI 2FNFX 1TBRR 1XBTA 1LR8A 5EX3A 1LR9A 2L7XA 3BJIA 2N71A 1HPTA 4HGUA 5JHWC 1OMTA 2N52A 3MEKA 1SGEI 3KY9A 3SGQI 4E1RA 2LUYA 2NU4I 1BUSA 2J9RA 1HDLA 3E59A 3OL0A 2DB6A 5CCMA 2OVOA 1H0ZA 1Y1CA 2K9HA 2WVJA 4FKDA 5FUYA 1HJAI 1RFHA 3OXLA 1CGJI 4GI3C 2GVIA 1OYVI 2GKVA 2YQPA 3UGDA 2L8EA 1W4RA 1IY6A 1SGPI 1Y1BA 2JYYA 1YTPA 2N1AB 1SGDI 4OVOA 4E1PA 2GKRI 1CSOI 1SGRI 2UZ3A 5FUVA 2QQCA 1IW4A 3HH2C 4UXIA 2YUUA 3RU0A 3B4VC 2ORVA 3OVOA 1M8CA 1XX6A 1PTQA 2V1CA 3UFFA 3VDPA 2ARPF 2JZMA 4UXHA 2WCYA 1W3SA 2NU1I 1OMUA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2QQD A;  3QTL D;  2GKT I;  1DS3 I;  2KCX A;  1LR7 A;  1UVG A;  2SGD I;  1SGN I;  2SGP I;  2NU3 I;  2BUS A;  2LEO A;  1IY5 A;  2KMR A;  1TBQ R;  5DAE A;  1BMO A;  1MT1 A;  1KMA A;  1CHO I;  2B0U C;  1YU6 C;  4SGB I;  1TUR A;  2P6A C;  2NU2 I;  1CT4 I;  1TGS I;  1FYB A;  1M8B A;  2F3C I;  2SGE I;  3SGB I;  1OVO A;  1UVF A;  1N13 A;  2KMO A;  2KMP A;  2XRC A;  1CT2 I;  2ERW A;  3TJQ A;  1PPF I;  1SGY I;  2KMQ A;  1TIH A;  1R0R I;  1PJU A;  1DS2 I;  1UUC A;  1NUB A;  1CGI I;  2N17 A;  3SEK C;  1AN1 I;  1CE3 A;  1CT0 I;  1SGQ I;  2V53 A;  1TUS A;  2JXD A;  1PCE A;  2SGQ I;  1Z7K B;  2M5X A;  2SGF I;  1TBR R;  1LR8 A;  1LR9 A;  2N71 A;  1HPT A;  4HGU A;  5JHW C;  1OMT A;  2N52 A;  1SGE I;  3SGQ I;  2NU4 I;  1BUS A;  1HDL A;  2OVO A;  1H0Z A;  1Y1C A;  1HJA I;  1CGJ I;  4GI3 C;  1OYV I;  2GKV A;  1IY6 A;  1SGP I;  1Y1B A;  2JYY A;  1YTP A;  1SGD I;  4OVO A;  2GKR I;  1CSO I;  1SGR I;  2QQC A;  1IW4 A;  3HH2 C;  3B4V C;  3OVO A;  1M8C A;  2ARP F;  2JZM A;  2WCY A;  2NU0 I;  2NU1 I;  1OMU A; 
#chains in the Genus database with same CATH topology
 2DKV A;  2QQD A;  1R79 A;  5HI7 A;  3QTL D;  3UGL A;  2GKT I;  3FC3 A;  1DS3 I;  2KCX A;  3R5A A;  1Q9B A;  4DNC A;  2ENN A;  1LR7 A;  1UVG A;  3UEY A;  1TOT A;  1SGN I;  2SGD I;  2SGP I;  2NU3 I;  3TOA A;  5J8C A;  3VDU A;  5FUW A;  1P9G A;  2BUS A;  3OXG A;  3UGI A;  2LEO A;  3CXL A;  1IY5 A;  2KMR A;  1ULN A;  1TBQ R;  3FSY A;  1S20 A;  2VRW B;  2QPO A;  4AML A;  2ROW A;  5DAE A;  7WGA A;  1K7T A;  1FAQ A;  1VDD A;  1X74 A;  2WGC A;  2E5R A;  3QAH A;  3TO6 A;  1BMO A;  1MT1 A;  2ENZ A;  2NU0 I;  3UEJ A;  1KMA A;  2ORW A;  1CHO I;  5EX0 A;  3E2I A;  2B0U C;  4UXJ A;  1PTR A;  3R5B A;  1YU6 C;  4SGB I;  9WGA A;  2JA1 A;  5E3P A;  4JCV E;  1TUR A;  2OZU A;  2ELI A;  2NU2 I;  1CT4 I;  1TGS I;  2DIP A;  2LB7 A;  2P6A C;  1MJA A;  1V1I A;  3VE5 A;  1M8B A;  2E73 A;  2V1C C;  2RIJ A;  2X52 A;  2F3C I;  1Z2I A;  3D00 A;  2SGE I;  2OD1 A;  1NXU A;  3OXF A;  3SGB I;  1OVO A;  2PQ8 A;  1UVF A;  2J87 A;  1MJB A;  1V1H A;  1N13 A;  5CCL A;  2KMO A;  1K7V A;  2KMP A;  2JW6 A;  2XRC A;  1CT2 I;  2ERW A;  2W0T A;  3TJQ A;  4B6D A;  1PPF I;  1SGY I;  2KMQ A;  1MJ9 A;  1TIH A;  1TBN A;  1R0R I;  1WKX A;  2CJS C;  2Y0M A;  1PJU A;  1DS2 I;  1FYB A;  5E3R A;  2A20 A;  1UUC A;  1NUB A;  2QQE A;  1CGI I;  2B8T A;  2N17 A;  4MPI A;  4WP4 A;  3SEK C;  1AN1 I;  1CE3 A;  5FUX A;  4L9M A;  1CT0 I;  1SGQ I;  2V53 A;  1Y8F A;  1KBF A;  1X4S A;  1HEV A;  5HQ8 A;  2ODD A;  1TUS A;  4A24 A;  2JXD A;  2QQ0 A;  1PCE A;  3PDN A;  1KBE A;  5E3Q A;  3R5D A;  2SGQ I;  1TBO A;  1Z7K B;  1U5K A;  2M5X A;  1FAR A;  1ULK A;  2OU2 A;  1XA6 A;  2SGF I;  2FNF X;  3QWP A;  1TBR R;  1XBT A;  1LR8 A;  3FSX A;  5EX3 A;  1WTJ A;  3UOE A;  1LR9 A;  2L7X A;  3BJI A;  2N71 A;  1HPT A;  4HGU A;  5JHW C;  1OMT A;  2GIV A;  2N52 A;  3TO9 A;  3MEK A;  1SGE I;  3KY9 A;  3SGQ I;  4E1R A;  2LUY A;  2NU4 I;  1P9Z A;  1BUS A;  2J9R A;  1HDL A;  3E59 A;  3OL0 A;  5J8F A;  2DB6 A;  5CCM A;  2OVO A;  1H0Z A;  1Y1C A;  2K9H A;  2WVJ A;  4FKD A;  5FUY A;  1HJA I;  1RFH A;  1K7U A;  3OXL A;  1CGJ I;  4GI3 C;  1WGT A;  1OYV I;  2GVI A;  2UVO A;  2X3T A;  2GKV A;  2YQP A;  3TO7 A;  1FY7 A;  3UGD A;  2L8E A;  1W4R A;  1IY6 A;  1SGP I;  1Y1B A;  2CWH A;  2JYY A;  1YTP A;  2N1A B;  1SGD I;  4OVO A;  4E1P A;  3R5C A;  1UHA A;  2GKR I;  1CSO I;  1SGR I;  1WGC A;  2UZ3 A;  5FUV A;  2QQC A;  1ULM A;  1IW4 A;  3HH2 C;  4UXI A;  2YUU A;  3RU0 A;  3B4V C;  3TOB A;  2ORV A;  2CWG A;  3OVO A;  1M8C A;  1XX6 A;  1PTQ A;  2V1C A;  3UFF A;  3VDP A;  2ARP F;  2JZM A;  2RC4 A;  3GOX A;  4UXH A;  2WCY A;  1W3S A;  2NU1 I;  1OMU A;  2CWF A; 
#chains in the Genus database with same CATH homology
 2QQD A;  5HI7 A;  1R79 A;  3QTL D;  3UGL A;  2GKT I;  3FC3 A;  1DS3 I;  2KCX A;  2ENN A;  1LR7 A;  1UVG A;  3UEY A;  1TOT A;  1SGN I;  2SGD I;  2SGP I;  2NU3 I;  3VDU A;  5FUW A;  2BUS A;  3OXG A;  3UGI A;  2LEO A;  3CXL A;  1IY5 A;  2KMR A;  1TBQ R;  2VRW B;  2ROW A;  5DAE A;  1FAQ A;  1VDD A;  1X74 A;  2E5R A;  1BMO A;  1MT1 A;  2ENZ A;  2NU0 I;  3UEJ A;  1KMA A;  2ORW A;  1CHO I;  5EX0 A;  3E2I A;  2B0U C;  4UXJ A;  1PTR A;  1YU6 C;  4SGB I;  2JA1 A;  1KBF A;  4JCV E;  1TUR A;  2P6A C;  2ELI A;  2NU2 I;  1CT4 I;  1TGS I;  2DIP A;  2QPO A;  3VE5 A;  1V1I A;  1FYB A;  1M8B A;  2E73 A;  2V1C C;  2F3C I;  3D00 A;  2SGE I;  2OD1 A;  3OXF A;  3SGB I;  1OVO A;  1UVF A;  2J87 A;  1V1H A;  1N13 A;  5CCL A;  2KMO A;  2KMP A;  2JW6 A;  2XRC A;  1CT2 I;  2ERW A;  2W0T A;  3TJQ A;  4B6D A;  1PPF I;  1SGY I;  2KMQ A;  1TIH A;  1TBN A;  1R0R I;  2CJS C;  1PJU A;  1DS2 I;  2A20 A;  1UUC A;  1NUB A;  2QQE A;  1CGI I;  2B8T A;  2N17 A;  3SEK C;  1AN1 I;  1CE3 A;  5FUX A;  4L9M A;  1CT0 I;  1SGQ I;  2V53 A;  1Y8F A;  1X4S A;  5HQ8 A;  2ODD A;  1TUS A;  4A24 A;  2JXD A;  2QQ0 A;  1PCE A;  3PDN A;  1KBE A;  2SGQ I;  1TBO A;  1Z7K B;  1U5K A;  2M5X A;  1FAR A;  3QWP A;  3GOX A;  1XA6 A;  2SGF I;  2FNF X;  1TBR R;  1XBT A;  1LR8 A;  5EX3 A;  1LR9 A;  2L7X A;  3BJI A;  2N71 A;  1HPT A;  4HGU A;  5JHW C;  1OMT A;  2N52 A;  3MEK A;  1SGE I;  3KY9 A;  3SGQ I;  4E1R A;  2LUY A;  2NU4 I;  1BUS A;  2J9R A;  1HDL A;  3E59 A;  3OL0 A;  2DB6 A;  5CCM A;  2OVO A;  1H0Z A;  1Y1C A;  2K9H A;  2WVJ A;  4FKD A;  5FUY A;  1HJA I;  1RFH A;  3OXL A;  1CGJ I;  4GI3 C;  2GVI A;  1OYV I;  2GKV A;  2YQP A;  3UGD A;  2L8E A;  1W4R A;  1IY6 A;  1SGP I;  1Y1B A;  2JYY A;  1YTP A;  2N1A B;  1SGD I;  4OVO A;  4E1P A;  2GKR I;  1CSO I;  1SGR I;  2UZ3 A;  5FUV A;  2QQC A;  1IW4 A;  3HH2 C;  4UXI A;  2YUU A;  3RU0 A;  3B4V C;  2ORV A;  3OVO A;  1M8C A;  1XX6 A;  1PTQ A;  2V1C A;  3UFF A;  3VDP A;  2ARP F;  2JZM A;  4UXH A;  2WCY A;  1W3S A;  2NU1 I;  1OMU A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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