2SGQI

Gln 18 variant of turkey ovomucoid inhibitor third domain complexed with streptomyces griseus proteinase b at ph 6.5
Total Genus 13
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
13
sequence length
51
structure length
51
Chain Sequence
VDCSEYPKPACTQEYRPLCGSDNKTYGNKCNFCNAVVESNGTLTLSHFGKC
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Recruitment of a Buried K+ Ion to Stabilize the Negative Charge of Ionized P1 in the Hydrophobic Pocket: Crystal Structures of Glu18, Gln18, Asp18 and Asn18 Variants of Turkey Ovomucoid Inhibitor Third Domain Complexed with Streptomyces griseus Protease B at Various pH's
rcsb
molecule tags Hydrolase/hydrolase inhibitor
source organism Meleagris gallopavo
molecule keywords Streptogrisin B
total genus 13
structure length 51
sequence length 51
ec nomenclature
pdb deposition date 1999-03-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
I PF00050 Kazal_1 Kazal-type serine protease inhibitor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.60.30 Alpha Beta 2-Layer Sandwich Wheat Germ Agglutinin (Isolectin 2); domain 1 Wheat Germ Agglutinin (Isolectin 2); domain 1 2sgqI00
4GI3C 2KCXA 2JZMA 2SGPI 2SGQI 1OYVI 1CSOI 4SGBI 1OMUA 1AN1I 1LR9A 2NU4I 1NUBA 1CE3A 1FYBA 1CGJI 1SGRI 1M8BA 2NU0I 2SGEI 1UVGA 1UUCA 2KMPA 1CT4I 2OVOA 2ARPF 1H0ZA 1UVFA 1R0RI 1OVOA 1SGNI 1TGSI 1Y1CA 1M8CA 3SGQI 1HJAI 1IW4A 1CT0I 1IY6A 1TUSA 2M5XA 1SGYI 3SGBI 1CHOI 1SGDI 1SGQI 1DS2I 1PJUA 4HGUA 4OVOA 1Y1BA 2XRCA 2WCYA 2QQDA 2GKTI 2KMQA 5JHWC 3B4VC 2GKVA 1YTPA 1SGEI 2QQCA 1CT2I 2NU3I 2KMOA 1IY5A 1TURA 1PPFI 1KMAA 1TBRR 1BMOA 3HH2C 1LR7A 2N71A 1HPTA 5DAEA 1SGPI 1CGII 1DS3I 2SGFI 2JYYA 2JXDA 3SEKC 2SGDI 2LEOA 3OVOA 1MT1A 2NU2I 1TBQR 2NU1I 1OMTA 2GKRI 1N13A 2KMRA 3TJQA 2F3CI 2V53A 3QTLD 1PCEA 1Z7KB 1BUSA 2BUSA 1HDLA 1YU6C 2P6AC 2N17A 2N52A 1TIHA 2ERWA 1LR8A 2B0UC
chains in the Genus database with same CATH superfamily
2QQ0A 4GI3C 2KCXA 1NXUA 2JZMA 1S20A 2SGQI 2SGPI 5FUWA 3TOBA 4A24A 1OYVI 1CSOI 2ELIA 4SGBI 3TO6A 1OMUA 1AN1I 1LR9A 2NU4I 1NUBA 1CE3A 1FYBA 1RFHA 4FKDA 1CGJI 3R5DA 1SGRI 1M8BA 5FUYA 1FARA 2NU0I 2B0UC 2SGEI 1KBFA 1UVGA 5CCMA 2GIVA 1UUCA 2ORWA 2KMPA 3UOEA 1CT4I 2OVOA 2ODDA 2ARPF 2B8TA 1H0ZA 1ULMA 1UVFA 4AMLA 1HEVA 1R0RI 3UGIA 2JA1A 1OVOA 2DB6A 1Q9BA 3QWPA 1Y8FA 1SGNI 1TGSI 2ERWA 1KBEA 2ROWA 1Y1CA 9WGAA 1M8CA 3SGQI 1W4RA 1IW4A 1CT0I 1U5KA 1IY6A 5CCLA 3FC3A 2J87A 1UHAA 1TUSA 2J9RA 1PTRA 2ORVA 1PTQA 2M5XA 2CWGA 3QAHA 3VE5A 3UEYA 1SGYI 2CJSC 3SGBI 2V1CC 3MEKA 2DIPA 4JCVE 1CHOI 1SGDI 1SGQI 1DS2I 1PJUA 2K9HA 4HGUA 4OVOA 7WGAA 5HQ8A 1VDDA 2QQEA 1Y1BA 2XRCA 1MJAA 1R79A 1K7VA 1ULKA 2WCYA 2FNFX 2QQDA 2GKTI 2YQPA 2PQ8A 3OXLA 3VDPA 1K7UA 2GVIA 4UXIA 1W3SA 2KMQA 5E3RA 5JHWC 4UXJA 2Y0MA 1WKXA 3B4VC 2UZ3A 4DNCA 2RC4A 2GKVA 1Z2IA 1V1IA 1MJBA 2LUYA 1YTPA 2E73A 3UGDA 1FAQA 1SGEI 2QQCA 1CT2I 2NU3I 1XBTA 2KMOA 1IY5A 2YUUA 1TURA 1PPFI 3R5CA 2X52A 2JW6A 3R5BA 2OD1A 4WP4A 1KMAA 3UGLA 1TBRR 1P9ZA 1BMOA 2ENNA 3HH2C 2LB7A 5HI7A 3BJIA 1TBOA 2RIJA 1K7TA 4E1RA 1LR7A 1V1HA 2N71A 1HPTA 5DAEA 4L9MA 3UFFA 3PDNA 1SGPI 2CWFA 1TOTA 5E3PA 2QPOA 1CGII 1DS3I 1X74A 2SGFI 3R5AA 3CXLA 3TO9A 2JYYA 2E5RA 4MPIA 2JXDA 3SEKC 3E2IA 3UEJA 1TBNA 2SGDI 1X4SA 2W0TA 5FUXA 2LEOA 2L8EA 5E3QA 3OXGA 3OVOA 1MT1A 2N1AB 2NU2I 1TBQR 2NU1I 2UVOA 1OMTA 2OU2A 2OZUA 2DKVA 1N13A 1ULNA 2GKRI 2KMRA 3RU0A 5FUVA 5J8FA 4E1PA 3VDUA 3TJQA 2F3CI 2V53A 3QTLD 1PCEA 1XA6A 3TOAA 1Z7KB 2WVJA 1WTJA 2CWHA 2VRWB 3D00A 3FSXA 4UXHA 2WGCA 4B6DA 2X3TA 3KY9A 1XX6A 2BUSA 5EX0A 1BUSA 2A20A 5J8CA 1HDLA 2V1CA 1FY7A 3TO7A 3GOXA 3FSYA 1MJ9A 1WGCA 1YU6C 2L7XA 2P6AC 2N17A 3OL0A 2N52A 1P9GA 3OXFA 1TIHA 1HJAI 3E59A 2ENZA 1LR8A 1WGTA 5EX3A
chains in the Genus database with same CATH topology
2QQ0A 4GI3C 2KCXA 2JZMA 2SGPI 5FUWA 2SGQI 4A24A 1OYVI 1CSOI 2ELIA 4SGBI 1OMUA 1AN1I 1LR9A 2NU4I 1NUBA 1CE3A 1FYBA 1RFHA 4FKDA 1CGJI 1SGRI 1M8BA 5FUYA 1FARA 2NU0I 2SGEI 1KBFA 1UVGA 5CCMA 2ORWA 1UUCA 2KMPA 1CT4I 2OVOA 2ODDA 2ARPF 2B8TA 1H0ZA 1UVFA 1R0RI 3UGIA 2JA1A 1OVOA 2DB6A 3QWPA 1Y8FA 1SGNI 1TGSI 2ERWA 1KBEA 2ROWA 1Y1CA 1M8CA 3SGQI 1W4RA 1IW4A 1CT0I 1U5KA 1IY6A 5CCLA 3FC3A 2J87A 2J9RA 1TUSA 2ORVA 1PTRA 1PTQA 2M5XA 3VE5A 3UEYA 1SGYI 2CJSC 3SGBI 2V1CC 3MEKA 2DIPA 4JCVE 1CHOI 1SGDI 1SGQI 1DS2I 1PJUA 2K9HA 4HGUA 4OVOA 5HQ8A 1VDDA 2QQEA 1Y1BA 2XRCA 1R79A 2WCYA 2YQPA 2FNFX 2QQDA 2GKTI 3OXLA 3VDPA 2GVIA 4UXIA 1W3SA 2KMQA 5JHWC 4UXJA 3B4VC 2UZ3A 2GKVA 1V1IA 2LUYA 1YTPA 2E73A 3UGDA 1FAQA 1SGEI 2QQCA 1CT2I 2NU3I 1XBTA 2KMOA 1IY5A 2YUUA 1TURA 1PPFI 2JW6A 2OD1A 1KMAA 3UGLA 1TBRR 1BMOA 2ENNA 3HH2C 5HI7A 3BJIA 1TBOA 4E1RA 1LR7A 1V1HA 2N71A 1HPTA 5DAEA 4L9MA 3UFFA 3PDNA 1SGPI 1TOTA 2QPOA 1CGII 1DS3I 1X74A 2SGFI 3CXLA 2JYYA 2E5RA 2JXDA 3SEKC 3E2IA 3UEJA 1TBNA 2SGDI 1X4SA 2W0TA 5FUXA 2LEOA 2L8EA 3OXGA 3OVOA 1MT1A 2N1AB 2NU2I 1TBQR 2NU1I 1OMTA 2GKRI 1N13A 3RU0A 2KMRA 5FUVA 4E1PA 3VDUA 3TJQA 2F3CI 2V53A 3QTLD 1PCEA 1XA6A 1Z7KB 2WVJA 2VRWB 3D00A 4UXHA 4B6DA 3KY9A 1XX6A 2BUSA 5EX0A 1BUSA 2A20A 1HDLA 2V1CA 3GOXA 1YU6C 2L7XA 2P6AC 3OL0A 2N17A 2N52A 3OXFA 1TIHA 1HJAI 3E59A 2ENZA 1LR8A 2B0UC 5EX3A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4GI3 C;  2KCX A;  2JZM A;  2SGP I;  2SGQ I;  1OYV I;  1CSO I;  4SGB I;  1OMU A;  1AN1 I;  1LR9 A;  2NU4 I;  1NUB A;  1CE3 A;  1FYB A;  1CGJ I;  1SGR I;  1M8B A;  2NU0 I;  2SGE I;  1UVG A;  1UUC A;  2KMP A;  1CT4 I;  2OVO A;  2ARP F;  1H0Z A;  1UVF A;  1R0R I;  1OVO A;  1SGN I;  1TGS I;  1Y1C A;  1M8C A;  3SGQ I;  1HJA I;  1IW4 A;  1CT0 I;  1IY6 A;  1TUS A;  2M5X A;  1SGY I;  3SGB I;  1CHO I;  1SGD I;  1SGQ I;  1DS2 I;  1PJU A;  4HGU A;  4OVO A;  1Y1B A;  2XRC A;  2WCY A;  2QQD A;  2GKT I;  2KMQ A;  5JHW C;  3B4V C;  2GKV A;  1YTP A;  1SGE I;  2QQC A;  1CT2 I;  2NU3 I;  2KMO A;  1IY5 A;  1TUR A;  1PPF I;  1KMA A;  1TBR R;  1BMO A;  3HH2 C;  1LR7 A;  2N71 A;  1HPT A;  5DAE A;  1SGP I;  1CGI I;  1DS3 I;  2SGF I;  2JYY A;  2JXD A;  3SEK C;  2SGD I;  2LEO A;  3OVO A;  1MT1 A;  2NU2 I;  1TBQ R;  2NU1 I;  1OMT A;  2GKR I;  1N13 A;  2KMR A;  3TJQ A;  2F3C I;  2V53 A;  3QTL D;  1PCE A;  1Z7K B;  1BUS A;  2BUS A;  1HDL A;  1YU6 C;  2P6A C;  2N17 A;  2N52 A;  1TIH A;  2ERW A;  1LR8 A;  2B0U C; 
#chains in the Genus database with same CATH topology
 2QQ0 A;  4GI3 C;  2KCX A;  1NXU A;  2JZM A;  1S20 A;  2SGQ I;  2SGP I;  5FUW A;  3TOB A;  4A24 A;  1OYV I;  1CSO I;  2ELI A;  4SGB I;  3TO6 A;  1OMU A;  1AN1 I;  1LR9 A;  2NU4 I;  1NUB A;  1CE3 A;  1FYB A;  1RFH A;  4FKD A;  1CGJ I;  3R5D A;  1SGR I;  1M8B A;  5FUY A;  1FAR A;  2NU0 I;  2B0U C;  2SGE I;  1KBF A;  1UVG A;  5CCM A;  2GIV A;  1UUC A;  2ORW A;  2KMP A;  3UOE A;  1CT4 I;  2OVO A;  2ODD A;  2ARP F;  2B8T A;  1H0Z A;  1ULM A;  1UVF A;  4AML A;  1HEV A;  1R0R I;  3UGI A;  2JA1 A;  1OVO A;  2DB6 A;  1Q9B A;  3QWP A;  1Y8F A;  1SGN I;  1TGS I;  2ERW A;  1KBE A;  2ROW A;  1Y1C A;  9WGA A;  1M8C A;  3SGQ I;  1W4R A;  1IW4 A;  1CT0 I;  1U5K A;  1IY6 A;  5CCL A;  3FC3 A;  2J87 A;  1UHA A;  1TUS A;  2J9R A;  1PTR A;  2ORV A;  1PTQ A;  2M5X A;  2CWG A;  3QAH A;  3VE5 A;  3UEY A;  1SGY I;  2CJS C;  3SGB I;  2V1C C;  3MEK A;  2DIP A;  4JCV E;  1CHO I;  1SGD I;  1SGQ I;  1DS2 I;  1PJU A;  2K9H A;  4HGU A;  4OVO A;  7WGA A;  5HQ8 A;  1VDD A;  2QQE A;  1Y1B A;  2XRC A;  1MJA A;  1R79 A;  1K7V A;  1ULK A;  2WCY A;  2FNF X;  2QQD A;  2GKT I;  2YQP A;  2PQ8 A;  3OXL A;  3VDP A;  1K7U A;  2GVI A;  4UXI A;  1W3S A;  2KMQ A;  5E3R A;  5JHW C;  4UXJ A;  2Y0M A;  1WKX A;  3B4V C;  2UZ3 A;  4DNC A;  2RC4 A;  2GKV A;  1Z2I A;  1V1I A;  1MJB A;  2LUY A;  1YTP A;  2E73 A;  3UGD A;  1FAQ A;  1SGE I;  2QQC A;  1CT2 I;  2NU3 I;  1XBT A;  2KMO A;  1IY5 A;  2YUU A;  1TUR A;  1PPF I;  3R5C A;  2X52 A;  2JW6 A;  3R5B A;  2OD1 A;  4WP4 A;  1KMA A;  3UGL A;  1TBR R;  1P9Z A;  1BMO A;  2ENN A;  3HH2 C;  2LB7 A;  5HI7 A;  3BJI A;  1TBO A;  2RIJ A;  1K7T A;  4E1R A;  1LR7 A;  1V1H A;  2N71 A;  1HPT A;  5DAE A;  4L9M A;  3UFF A;  3PDN A;  1SGP I;  2CWF A;  1TOT A;  5E3P A;  2QPO A;  1CGI I;  1DS3 I;  1X74 A;  2SGF I;  3R5A A;  3CXL A;  3TO9 A;  2JYY A;  2E5R A;  4MPI A;  2JXD A;  3SEK C;  3E2I A;  3UEJ A;  1TBN A;  2SGD I;  1X4S A;  2W0T A;  5FUX A;  2LEO A;  2L8E A;  5E3Q A;  3OXG A;  3OVO A;  1MT1 A;  2N1A B;  2NU2 I;  1TBQ R;  2NU1 I;  2UVO A;  1OMT A;  2OU2 A;  2OZU A;  2DKV A;  1N13 A;  1ULN A;  2GKR I;  2KMR A;  3RU0 A;  5FUV A;  5J8F A;  4E1P A;  3VDU A;  3TJQ A;  2F3C I;  2V53 A;  3QTL D;  1PCE A;  1XA6 A;  3TOA A;  1Z7K B;  2WVJ A;  1WTJ A;  2CWH A;  2VRW B;  3D00 A;  3FSX A;  4UXH A;  2WGC A;  4B6D A;  2X3T A;  3KY9 A;  1XX6 A;  2BUS A;  5EX0 A;  1BUS A;  2A20 A;  5J8C A;  1HDL A;  2V1C A;  1FY7 A;  3TO7 A;  3GOX A;  3FSY A;  1MJ9 A;  1WGC A;  1YU6 C;  2L7X A;  2P6A C;  2N17 A;  3OL0 A;  2N52 A;  1P9G A;  3OXF A;  1TIH A;  1HJA I;  3E59 A;  2ENZ A;  1LR8 A;  1WGT A;  5EX3 A; 
#chains in the Genus database with same CATH homology
 2QQ0 A;  4GI3 C;  2KCX A;  2JZM A;  2SGP I;  5FUW A;  2SGQ I;  4A24 A;  1OYV I;  1CSO I;  2ELI A;  4SGB I;  1OMU A;  1AN1 I;  1LR9 A;  2NU4 I;  1NUB A;  1CE3 A;  1FYB A;  1RFH A;  4FKD A;  1CGJ I;  1SGR I;  1M8B A;  5FUY A;  1FAR A;  2NU0 I;  2SGE I;  1KBF A;  1UVG A;  5CCM A;  2ORW A;  1UUC A;  2KMP A;  1CT4 I;  2OVO A;  2ODD A;  2ARP F;  2B8T A;  1H0Z A;  1UVF A;  1R0R I;  3UGI A;  2JA1 A;  1OVO A;  2DB6 A;  3QWP A;  1Y8F A;  1SGN I;  1TGS I;  2ERW A;  1KBE A;  2ROW A;  1Y1C A;  1M8C A;  3SGQ I;  1W4R A;  1IW4 A;  1CT0 I;  1U5K A;  1IY6 A;  5CCL A;  3FC3 A;  2J87 A;  2J9R A;  1TUS A;  2ORV A;  1PTR A;  1PTQ A;  2M5X A;  3VE5 A;  3UEY A;  1SGY I;  2CJS C;  3SGB I;  2V1C C;  3MEK A;  2DIP A;  4JCV E;  1CHO I;  1SGD I;  1SGQ I;  1DS2 I;  1PJU A;  2K9H A;  4HGU A;  4OVO A;  5HQ8 A;  1VDD A;  2QQE A;  1Y1B A;  2XRC A;  1R79 A;  2WCY A;  2YQP A;  2FNF X;  2QQD A;  2GKT I;  3OXL A;  3VDP A;  2GVI A;  4UXI A;  1W3S A;  2KMQ A;  5JHW C;  4UXJ A;  3B4V C;  2UZ3 A;  2GKV A;  1V1I A;  2LUY A;  1YTP A;  2E73 A;  3UGD A;  1FAQ A;  1SGE I;  2QQC A;  1CT2 I;  2NU3 I;  1XBT A;  2KMO A;  1IY5 A;  2YUU A;  1TUR A;  1PPF I;  2JW6 A;  2OD1 A;  1KMA A;  3UGL A;  1TBR R;  1BMO A;  2ENN A;  3HH2 C;  5HI7 A;  3BJI A;  1TBO A;  4E1R A;  1LR7 A;  1V1H A;  2N71 A;  1HPT A;  5DAE A;  4L9M A;  3UFF A;  3PDN A;  1SGP I;  1TOT A;  2QPO A;  1CGI I;  1DS3 I;  1X74 A;  2SGF I;  3CXL A;  2JYY A;  2E5R A;  2JXD A;  3SEK C;  3E2I A;  3UEJ A;  1TBN A;  2SGD I;  1X4S A;  2W0T A;  5FUX A;  2LEO A;  2L8E A;  3OXG A;  3OVO A;  1MT1 A;  2N1A B;  2NU2 I;  1TBQ R;  2NU1 I;  1OMT A;  2GKR I;  1N13 A;  3RU0 A;  2KMR A;  5FUV A;  4E1P A;  3VDU A;  3TJQ A;  2F3C I;  2V53 A;  3QTL D;  1PCE A;  1XA6 A;  1Z7K B;  2WVJ A;  2VRW B;  3D00 A;  4UXH A;  4B6D A;  3KY9 A;  1XX6 A;  2BUS A;  5EX0 A;  1BUS A;  2A20 A;  1HDL A;  2V1C A;  3GOX A;  1YU6 C;  2L7X A;  2P6A C;  3OL0 A;  2N17 A;  2N52 A;  3OXF A;  1TIH A;  1HJA I;  3E59 A;  2ENZ A;  1LR8 A;  2B0U C;  5EX3 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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