2WCYA

Nmr solution structure of factor i-like modules of complement c7.
Total Genus 27
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
27
sequence length
155
structure length
155
Chain Sequence
GSHMNPLTQAVPKCQRWEKLQNSRCVCKMPYECGPSLDVCAQDERSKRILPLTVCKMHVLHCQGRNYTLTGRDSCTLPASAEKACGACPLWGKCDAESSKCVCREASECEEEGFSICVEVNGKEQTMSECEAGALRCRGQSISVTSIRPCAAETQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords COMPLEMENT COMPONENT C7
publication title Solution Structure of Factor I-Like Modules from Complement C7 Reveals a Pair of Follistatin Domains in Compact Pseudosymmetric Arrangement.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Immune system
total genus 27
structure length 155
sequence length 155
ec nomenclature
pdb deposition date 2009-03-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF18434 Kazal_3 Kazal-type serine protease inhibitor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.60.30 Alpha Beta 2-Layer Sandwich Wheat Germ Agglutinin (Isolectin 2); domain 1 Wheat Germ Agglutinin (Isolectin 2); domain 1 2wcyA01
3.30.60.30 Alpha Beta 2-Layer Sandwich Wheat Germ Agglutinin (Isolectin 2); domain 1 Wheat Germ Agglutinin (Isolectin 2); domain 1 2wcyA02
1SGEI 1DS2I 1UUCA 1M8CA 1IY6A 2KMPA 3HH2C 1SGRI 1CGJI 4OVOA 1TUSA 1KMAA 2NU0I 4SGBI 3OVOA 1LR8A 2KMRA 2P6AC 1HPTA 2SGPI 1Y1CA 1YTPA 1TBQR 2QQDA 1MT1A 1OMTA 2N52A 1TGSI 2JXDA 5JHWC 4HGUA 5DAEA 1NUBA 1AN1I 2GKTI 2N17A 1CGII 1PCEA 2KCXA 1TURA 1SGQI 1IW4A 1BUSA 1R0RI 1SGPI 2SGQI 2QQCA 3SEKC 1SGYI 1H0ZA 1HJAI 2GKRI 1Y1BA 1LR7A 1IY5A 2KMQA 1PPFI 1PJUA 1CT2I 2B0UC 2NU3I 2SGFI 2JZMA 2V53A 1CE3A 2WCYA 2LEOA 2F3CI 2ERWA 1HDLA 3TJQA 1TIHA 2SGEI 3QTLD 3B4VC 2NU4I 1TBRR 4GI3C 2NU1I 1SGDI 2KMOA 2N71A 3SGQI 1N13A 1OMUA 1OYVI 2M5XA 1CSOI 2GKVA 1Z7KB 1UVGA 2SGDI 1FYBA 1OVOA 3SGBI 2XRCA 1BMOA 2BUSA 1M8BA 2OVOA 1LR9A 2NU2I 1CT4I 1DS3I 2ARPF 1CHOI 1YU6C 1UVFA 1SGNI 1CT0I 2JYYA
chains in the Genus database with same CATH superfamily
1SGEI 3QWPA 1DS2I 1MJAA 1KBEA 2A20A 4UXJA 2E5RA 2X52A 1UUCA 3UGDA 1PTQA 1M8CA 1IY6A 2KMPA 1Q9BA 2E73A 3HH2C 3QAHA 1SGRI 1CGJI 9WGAA 1FARA 4OVOA 1TUSA 1KMAA 1WKXA 1K7UA 2DB6A 2NU0I 4SGBI 5EX0A 3OVOA 1LR8A 1U5KA 1WGCA 2KMRA 2LUYA 3UGIA 5E3QA 2P6AC 1ULKA 1HPTA 2RIJA 1TBOA 5FUXA 3GOXA 3BJIA 2YQPA 5J8CA 2V1CA 2FNFX 2WGCA 3UEYA 2CWFA 4AMLA 5CCLA 1WGTA 4L9MA 3VDUA 2SGPI 1ULMA 1Y1CA 3E59A 1X4SA 1YTPA 1TBQR 2UZ3A 2QQDA 1MT1A 1OMTA 2LB7A 3R5CA 2N52A 2CJSC 3PDNA 5EX3A 3RU0A 3UEJA 3VDPA 1K7VA 1TGSI 2JXDA 3TO6A 5JHWC 3FC3A 2ENZA 4HGUA 2CWGA 2J9RA 1P9GA 2DIPA 1FAQA 2B8TA 5DAEA 2K9HA 1TOTA 1W4RA 1NUBA 2QQEA 1S20A 1AN1I 1ULNA 2GKTI 2N17A 4UXHA 2RC4A 2N1AB 1CGII 1PCEA 2KCXA 1UHAA 1TURA 1K7TA 1Z2IA 3OXLA 3UGLA 1SGQI 1IW4A 1X74A 2OD1A 1RFHA 1BUSA 1FY7A 4JCVE 2X3TA 4E1PA 1R0RI 1NXUA 2GIVA 1KBFA 1SGPI 5HI7A 3OXFA 2SGQI 2QQCA 2V1CC 1PTRA 5HQ8A 3SEKC 1SGYI 5J8FA 1V1IA 3D00A 3TOBA 1H0ZA 1HJAI 1HEVA 2GKRI 3FSYA 1Y1BA 4MPIA 1LR7A 1IY5A 3OL0A 2KMQA 1PPFI 5FUYA 3VE5A 1P9ZA 1PJUA 1CT2I 2B0UC 3UFFA 2NU3I 1Y8FA 2ORWA 3TO9A 2SGFI 2UVOA 2JW6A 2QQ0A 7WGAA 2DKVA 2YUUA 2JZMA 2V53A 5E3RA 1W3SA 2WCYA 1CE3A 2OU2A 2LEOA 2VRWB 4UXIA 2F3CI 3MEKA 2OZUA 2ERWA 2ODDA 4E1RA 2L8EA 4A24A 1HDLA 3TJQA 1TIHA 2Y0MA 2SGEI 5E3PA 3QTLD 2ROWA 2NU4I 3B4VC 5CCMA 4WP4A 3CXLA 1TBRR 4FKDA 4GI3C 2NU1I 1VDDA 1SGDI 3TOAA 2KMOA 2N71A 2CWHA 1MJ9A 1N13A 1TBNA 3SGQI 1OMUA 1OYVI 2L7XA 1CSOI 2GKVA 2M5XA 1Z7KB 3R5BA 1UVGA 2SGDI 1MJBA 3R5AA 2PQ8A 3R5DA 3UOEA 2ELIA 1FYBA 1OVOA 3KY9A 3SGBI 2QPOA 2WVJA 2XRCA 2W0TA 3TO7A 4DNCA 1BMOA 5FUVA 2BUSA 2ENNA 1XA6A 1M8BA 1XBTA 2OVOA 1LR9A 1V1HA 2JA1A 2GVIA 1XX6A 2NU2I 1CT4I 1DS3I 1R79A 2ARPF 1CHOI 1YU6C 2J87A 2ORVA 3OXGA 5FUWA 3FSXA 4B6DA 1UVFA 1SGNI 1CT0I 3E2IA 2JYYA 1WTJA
chains in the Genus database with same CATH topology
1SGEI 3QWPA 1DS2I 1KBEA 2A20A 4UXJA 2E5RA 1UUCA 3UGDA 1PTQA 1M8CA 1IY6A 2KMPA 3HH2C 2E73A 1SGRI 1CGJI 1FARA 4OVOA 1TUSA 1KMAA 2NU0I 2DB6A 4SGBI 5EX0A 3OVOA 1LR8A 1U5KA 2KMRA 2LUYA 3UGIA 2P6AC 1HPTA 5FUXA 1TBOA 3GOXA 3BJIA 2YQPA 2V1CA 2FNFX 3UEYA 5CCLA 4L9MA 3VDUA 2SGPI 1Y1CA 3E59A 1X4SA 1YTPA 1TBQR 2UZ3A 2QQDA 1MT1A 1OMTA 5EX3A 3RU0A 2N52A 2CJSC 3PDNA 3UEJA 3VDPA 1TGSI 2JXDA 3FC3A 5JHWC 2ENZA 4HGUA 1FAQA 2J9RA 2DIPA 2B8TA 5DAEA 2K9HA 1TOTA 1W4RA 1NUBA 2QQEA 1AN1I 2GKTI 2N17A 4UXHA 2N1AB 1CGII 1PCEA 2KCXA 1TURA 3OXLA 3UGLA 1SGQI 1IW4A 1X74A 2OD1A 1RFHA 1BUSA 4JCVE 4E1PA 1R0RI 1KBFA 1SGPI 5HI7A 3OXFA 2SGQI 2QQCA 2V1CC 1PTRA 5HQ8A 3SEKC 1SGYI 1V1IA 3D00A 1H0ZA 1HJAI 2GKRI 1Y1BA 1LR7A 1IY5A 3OL0A 2KMQA 1PPFI 5FUYA 3VE5A 1PJUA 1CT2I 2B0UC 3UFFA 2NU3I 1Y8FA 2ORWA 2SGFI 2JW6A 2QQ0A 2YUUA 2JZMA 2V53A 1CE3A 1W3SA 2WCYA 2LEOA 2VRWB 4UXIA 2F3CI 3MEKA 2ERWA 2ODDA 4E1RA 2L8EA 4A24A 1HDLA 3TJQA 1TIHA 2SGEI 3QTLD 2ROWA 2NU4I 3B4VC 5CCMA 3CXLA 1TBRR 4FKDA 4GI3C 2NU1I 1VDDA 1SGDI 2KMOA 2N71A 3SGQI 1N13A 1TBNA 1OMUA 1OYVI 2L7XA 1CSOI 2GKVA 2M5XA 1Z7KB 1UVGA 2SGDI 2ELIA 1FYBA 1OVOA 3KY9A 3SGBI 2QPOA 2WVJA 2XRCA 2W0TA 1BMOA 5FUVA 2BUSA 2ENNA 1XA6A 1M8BA 1XBTA 2OVOA 1LR9A 1V1HA 2JA1A 2GVIA 1XX6A 2NU2I 1CT4I 1DS3I 1R79A 2ARPF 1CHOI 1YU6C 2J87A 2ORVA 3OXGA 5FUWA 4B6DA 1UVFA 1SGNI 1CT0I 3E2IA 2JYYA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1SGE I;  1DS2 I;  1UUC A;  1M8C A;  1IY6 A;  2KMP A;  3HH2 C;  1SGR I;  1CGJ I;  4OVO A;  1TUS A;  1KMA A;  2NU0 I;  4SGB I;  3OVO A;  1LR8 A;  2KMR A;  2P6A C;  1HPT A;  2SGP I;  1Y1C A;  1YTP A;  1TBQ R;  2QQD A;  1MT1 A;  1OMT A;  2N52 A;  1TGS I;  2JXD A;  5JHW C;  4HGU A;  5DAE A;  1NUB A;  1AN1 I;  2GKT I;  2N17 A;  1CGI I;  1PCE A;  2KCX A;  1TUR A;  1SGQ I;  1IW4 A;  1BUS A;  1R0R I;  1SGP I;  2SGQ I;  2QQC A;  3SEK C;  1SGY I;  1H0Z A;  1HJA I;  2GKR I;  1Y1B A;  1LR7 A;  1IY5 A;  2KMQ A;  1PPF I;  1PJU A;  1CT2 I;  2B0U C;  2NU3 I;  2SGF I;  2JZM A;  2V53 A;  1CE3 A;  2WCY A;  2LEO A;  2F3C I;  2ERW A;  1HDL A;  3TJQ A;  1TIH A;  2SGE I;  3QTL D;  3B4V C;  2NU4 I;  1TBR R;  4GI3 C;  2NU1 I;  1SGD I;  2KMO A;  2N71 A;  3SGQ I;  1N13 A;  1OMU A;  1OYV I;  2M5X A;  1CSO I;  2GKV A;  1Z7K B;  1UVG A;  2SGD I;  1FYB A;  1OVO A;  3SGB I;  2XRC A;  1BMO A;  2BUS A;  1M8B A;  2OVO A;  1LR9 A;  2NU2 I;  1CT4 I;  1DS3 I;  2ARP F;  1CHO I;  1YU6 C;  1UVF A;  1SGN I;  1CT0 I;  2JYY A; 
#chains in the Genus database with same CATH topology
 1SGE I;  3QWP A;  1DS2 I;  1MJA A;  1KBE A;  2A20 A;  4UXJ A;  2E5R A;  2X52 A;  1UUC A;  3UGD A;  1PTQ A;  1M8C A;  1IY6 A;  2KMP A;  1Q9B A;  2E73 A;  3HH2 C;  3QAH A;  1SGR I;  1CGJ I;  9WGA A;  1FAR A;  4OVO A;  1TUS A;  1KMA A;  1WKX A;  1K7U A;  2DB6 A;  2NU0 I;  4SGB I;  5EX0 A;  3OVO A;  1LR8 A;  1U5K A;  1WGC A;  2KMR A;  2LUY A;  3UGI A;  5E3Q A;  2P6A C;  1ULK A;  1HPT A;  2RIJ A;  1TBO A;  5FUX A;  3GOX A;  3BJI A;  2YQP A;  5J8C A;  2V1C A;  2FNF X;  2WGC A;  3UEY A;  2CWF A;  4AML A;  5CCL A;  1WGT A;  4L9M A;  3VDU A;  2SGP I;  1ULM A;  1Y1C A;  3E59 A;  1X4S A;  1YTP A;  1TBQ R;  2UZ3 A;  2QQD A;  1MT1 A;  1OMT A;  2LB7 A;  3R5C A;  2N52 A;  2CJS C;  3PDN A;  5EX3 A;  3RU0 A;  3UEJ A;  3VDP A;  1K7V A;  1TGS I;  2JXD A;  3TO6 A;  5JHW C;  3FC3 A;  2ENZ A;  4HGU A;  2CWG A;  2J9R A;  1P9G A;  2DIP A;  1FAQ A;  2B8T A;  5DAE A;  2K9H A;  1TOT A;  1W4R A;  1NUB A;  2QQE A;  1S20 A;  1AN1 I;  1ULN A;  2GKT I;  2N17 A;  4UXH A;  2RC4 A;  2N1A B;  1CGI I;  1PCE A;  2KCX A;  1UHA A;  1TUR A;  1K7T A;  1Z2I A;  3OXL A;  3UGL A;  1SGQ I;  1IW4 A;  1X74 A;  2OD1 A;  1RFH A;  1BUS A;  1FY7 A;  4JCV E;  2X3T A;  4E1P A;  1R0R I;  1NXU A;  2GIV A;  1KBF A;  1SGP I;  5HI7 A;  3OXF A;  2SGQ I;  2QQC A;  2V1C C;  1PTR A;  5HQ8 A;  3SEK C;  1SGY I;  5J8F A;  1V1I A;  3D00 A;  3TOB A;  1H0Z A;  1HJA I;  1HEV A;  2GKR I;  3FSY A;  1Y1B A;  4MPI A;  1LR7 A;  1IY5 A;  3OL0 A;  2KMQ A;  1PPF I;  5FUY A;  3VE5 A;  1P9Z A;  1PJU A;  1CT2 I;  2B0U C;  3UFF A;  2NU3 I;  1Y8F A;  2ORW A;  3TO9 A;  2SGF I;  2UVO A;  2JW6 A;  2QQ0 A;  7WGA A;  2DKV A;  2YUU A;  2JZM A;  2V53 A;  5E3R A;  1W3S A;  2WCY A;  1CE3 A;  2OU2 A;  2LEO A;  2VRW B;  4UXI A;  2F3C I;  3MEK A;  2OZU A;  2ERW A;  2ODD A;  4E1R A;  2L8E A;  4A24 A;  1HDL A;  3TJQ A;  1TIH A;  2Y0M A;  2SGE I;  5E3P A;  3QTL D;  2ROW A;  2NU4 I;  3B4V C;  5CCM A;  4WP4 A;  3CXL A;  1TBR R;  4FKD A;  4GI3 C;  2NU1 I;  1VDD A;  1SGD I;  3TOA A;  2KMO A;  2N71 A;  2CWH A;  1MJ9 A;  1N13 A;  1TBN A;  3SGQ I;  1OMU A;  1OYV I;  2L7X A;  1CSO I;  2GKV A;  2M5X A;  1Z7K B;  3R5B A;  1UVG A;  2SGD I;  1MJB A;  3R5A A;  2PQ8 A;  3R5D A;  3UOE A;  2ELI A;  1FYB A;  1OVO A;  3KY9 A;  3SGB I;  2QPO A;  2WVJ A;  2XRC A;  2W0T A;  3TO7 A;  4DNC A;  1BMO A;  5FUV A;  2BUS A;  2ENN A;  1XA6 A;  1M8B A;  1XBT A;  2OVO A;  1LR9 A;  1V1H A;  2JA1 A;  2GVI A;  1XX6 A;  2NU2 I;  1CT4 I;  1DS3 I;  1R79 A;  2ARP F;  1CHO I;  1YU6 C;  2J87 A;  2ORV A;  3OXG A;  5FUW A;  3FSX A;  4B6D A;  1UVF A;  1SGN I;  1CT0 I;  3E2I A;  2JYY A;  1WTJ A; 
#chains in the Genus database with same CATH homology
 1SGE I;  3QWP A;  1DS2 I;  1KBE A;  2A20 A;  4UXJ A;  2E5R A;  1UUC A;  3UGD A;  1PTQ A;  1M8C A;  1IY6 A;  2KMP A;  3HH2 C;  2E73 A;  1SGR I;  1CGJ I;  1FAR A;  4OVO A;  1TUS A;  1KMA A;  2NU0 I;  2DB6 A;  4SGB I;  5EX0 A;  3OVO A;  1LR8 A;  1U5K A;  2KMR A;  2LUY A;  3UGI A;  2P6A C;  1HPT A;  5FUX A;  1TBO A;  3GOX A;  3BJI A;  2YQP A;  2V1C A;  2FNF X;  3UEY A;  5CCL A;  4L9M A;  3VDU A;  2SGP I;  1Y1C A;  3E59 A;  1X4S A;  1YTP A;  1TBQ R;  2UZ3 A;  2QQD A;  1MT1 A;  1OMT A;  5EX3 A;  3RU0 A;  2N52 A;  2CJS C;  3PDN A;  3UEJ A;  3VDP A;  1TGS I;  2JXD A;  3FC3 A;  5JHW C;  2ENZ A;  4HGU A;  1FAQ A;  2J9R A;  2DIP A;  2B8T A;  5DAE A;  2K9H A;  1TOT A;  1W4R A;  1NUB A;  2QQE A;  1AN1 I;  2GKT I;  2N17 A;  4UXH A;  2N1A B;  1CGI I;  1PCE A;  2KCX A;  1TUR A;  3OXL A;  3UGL A;  1SGQ I;  1IW4 A;  1X74 A;  2OD1 A;  1RFH A;  1BUS A;  4JCV E;  4E1P A;  1R0R I;  1KBF A;  1SGP I;  5HI7 A;  3OXF A;  2SGQ I;  2QQC A;  2V1C C;  1PTR A;  5HQ8 A;  3SEK C;  1SGY I;  1V1I A;  3D00 A;  1H0Z A;  1HJA I;  2GKR I;  1Y1B A;  1LR7 A;  1IY5 A;  3OL0 A;  2KMQ A;  1PPF I;  5FUY A;  3VE5 A;  1PJU A;  1CT2 I;  2B0U C;  3UFF A;  2NU3 I;  1Y8F A;  2ORW A;  2SGF I;  2JW6 A;  2QQ0 A;  2YUU A;  2JZM A;  2V53 A;  1CE3 A;  1W3S A;  2WCY A;  2LEO A;  2VRW B;  4UXI A;  2F3C I;  3MEK A;  2ERW A;  2ODD A;  4E1R A;  2L8E A;  4A24 A;  1HDL A;  3TJQ A;  1TIH A;  2SGE I;  3QTL D;  2ROW A;  2NU4 I;  3B4V C;  5CCM A;  3CXL A;  1TBR R;  4FKD A;  4GI3 C;  2NU1 I;  1VDD A;  1SGD I;  2KMO A;  2N71 A;  3SGQ I;  1N13 A;  1TBN A;  1OMU A;  1OYV I;  2L7X A;  1CSO I;  2GKV A;  2M5X A;  1Z7K B;  1UVG A;  2SGD I;  2ELI A;  1FYB A;  1OVO A;  3KY9 A;  3SGB I;  2QPO A;  2WVJ A;  2XRC A;  2W0T A;  1BMO A;  5FUV A;  2BUS A;  2ENN A;  1XA6 A;  1M8B A;  1XBT A;  2OVO A;  1LR9 A;  1V1H A;  2JA1 A;  2GVI A;  1XX6 A;  2NU2 I;  1CT4 I;  1DS3 I;  1R79 A;  2ARP F;  1CHO I;  1YU6 C;  2J87 A;  2ORV A;  3OXG A;  5FUW A;  4B6D A;  1UVF A;  1SGN I;  1CT0 I;  3E2I A;  2JYY A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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