2WCYA

Nmr solution structure of factor i-like modules of complement c7.
Total Genus 27
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
27
sequence length
155
structure length
155
Chain Sequence
GSHMNPLTQAVPKCQRWEKLQNSRCVCKMPYECGPSLDVCAQDERSKRILPLTVCKMHVLHCQGRNYTLTGRDSCTLPASAEKACGACPLWGKCDAESSKCVCREASECEEEGFSICVEVNGKEQTMSECEAGALRCRGQSISVTSIRPCAAETQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords COMPLEMENT COMPONENT C7
publication title Solution Structure of Factor I-Like Modules from Complement C7 Reveals a Pair of Follistatin Domains in Compact Pseudosymmetric Arrangement.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Immune system
total genus 27
structure length 155
sequence length 155
ec nomenclature
pdb deposition date 2009-03-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF18434 Kazal_3 Kazal-type serine protease inhibitor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.60.30 Alpha Beta 2-Layer Sandwich Wheat Germ Agglutinin (Isolectin 2); domain 1 Wheat Germ Agglutinin (Isolectin 2); domain 1 2wcyA01
3.30.60.30 Alpha Beta 2-Layer Sandwich Wheat Germ Agglutinin (Isolectin 2); domain 1 Wheat Germ Agglutinin (Isolectin 2); domain 1 2wcyA02
1CGJI 2KMOA 2SGPI 1DS3I 1UVGA 2N71A 3QTLD 3SGQI 2NU0I 2M5XA 1OVOA 1M8BA 2JZMA 1KMAA 1SGPI 1UVFA 1IW4A 1CHOI 2ERWA 2OVOA 2P6AC 2XRCA 1SGQI 2KMQA 2KCXA 2WCYA 1AN1I 1N13A 2QQDA 4HGUA 2KMPA 2BUSA 2QQCA 2GKVA 1DS2I 2NU1I 1HPTA 2JXDA 2SGDI 1CT2I 1TUSA 3SEKC 1MT1A 1LR7A 1TBRR 2NU2I 1TGSI 1CE3A 1OMUA 1TBQR 1SGNI 1BUSA 2JYYA 1OYVI 1OMTA 5JHWC 2GKRI 1CGII 2SGEI 2N17A 1IY6A 2N52A 4GI3C 1NUBA 1H0ZA 2B0UC 2NU3I 2KMRA 1SGYI 1Y1BA 3OVOA 2V53A 1FYBA 2NU4I 1PCEA 1UUCA 1LR9A 3TJQA 1R0RI 1TURA 2SGFI 1HDLA 2LEOA 1Y1CA 1YTPA 1PPFI 1CSOI 3SGBI 1HJAI 1PJUA 1IY5A 4OVOA 1BMOA 1M8CA 3HH2C 1SGEI 1SGDI 1LR8A 1Z7KB 1YU6C 1CT4I 2GKTI 3B4VC 2SGQI 1SGRI 2F3CI 4SGBI 5DAEA 1TIHA 1CT0I 2ARPF
chains in the Genus database with same CATH superfamily
1CGJI 2ENZA 2DIPA 2KMOA 2SGPI 4B6DA 1DS3I 1UVGA 2E73A 2N71A 1PTQA 3QTLD 2NU0I 2M5XA 3SGQI 1OVOA 2A20A 2VRWB 3QWPA 3UEYA 2W0TA 1M8BA 2JZMA 4A24A 1KMAA 3E2IA 1NXUA 1SGPI 1UVFA 1MJAA 1X4SA 5EX3A 3TOBA 1IW4A 1UHAA 2GVIA 1CHOI 3BJIA 2WVJA 1WKXA 3TO9A 2ERWA 1K7UA 1ULMA 2OVOA 2ROWA 2GIVA 5J8FA 3VDPA 3R5BA 2JW6A 2P6AC 4MPIA 2XRCA 1KBFA 4L9MA 1RFHA 3UEJA 4AMLA 2ELIA 2RIJA 2OZUA 1SGQI 2KMQA 5EX0A 1ULNA 2KCXA 2WCYA 3RU0A 1AN1I 1N13A 2DKVA 2K9HA 2LUYA 2QQDA 4HGUA 5E3QA 2KMPA 2YUUA 2BUSA 2QQCA 2GKVA 1FY7A 2QQ0A 3OL0A 1DS2I 3FSYA 1K7VA 3MEKA 4FKDA 2NU1I 3TO7A 1HPTA 1U5KA 2JXDA 1V1IA 4DNCA 2SGDI 1CT2I 1P9ZA 1TUSA 1Q9BA 2J9RA 3UOEA 3SEKC 1MT1A 1LR7A 4E1PA 2V1CA 3UGIA 2L8EA 1XA6A 1WGTA 3QAHA 5E3RA 1TBRR 9WGAA 1R79A 1FAQA 1ULKA 2NU2I 1TGSI 1W3SA 1VDDA 2QQEA 1CE3A 1MJBA 1OMUA 1TBQR 2X52A 1SGNI 4UXHA 2FNFX 2JYYA 1OYVI 1Y8FA 1OMTA 2UZ3A 2E5RA 2CWHA 5FUVA 5JHWC 1HEVA 5CCMA 2ENNA 2GKRI 5FUWA 1CGII 2LB7A 1FARA 2J87A 4E1RA 7WGAA 3OXGA 1MJ9A 2SGEI 2N17A 3VE5A 2CWFA 5J8CA 1TBOA 1IY6A 2ODDA 4JCVE 1V1HA 2N52A 4UXIA 4GI3C 3R5DA 1NUBA 3UGDA 1H0ZA 2B0UC 3R5CA 2NU3I 2KMRA 1SGYI 1Y1BA 3OVOA 2OU2A 2DB6A 2OD1A 2L7XA 2CJSC 4UXJA 5FUXA 2V53A 1FYBA 2NU4I 1XBTA 3KY9A 3OXFA 1BUSA 1PCEA 3D00A 1UUCA 1LR9A 1X74A 1R0RI 3TJQA 2Y0MA 1TURA 2SGFI 3CXLA 3VDUA 2ORVA 1HDLA 2LEOA 3OXLA 3UFFA 1TBNA 1Y1CA 2QPOA 3FSXA 1YTPA 1W4RA 1PPFI 2UVOA 1P9GA 3TOAA 1CSOI 3SGBI 1HJAI 1PJUA 1KBEA 2JA1A 3TO6A 1Z2IA 5CCLA 1IY5A 2CWGA 2X3TA 2YQPA 4OVOA 3UGLA 2ORWA 2PQ8A 1BMOA 1M8CA 2WGCA 3HH2C 1SGEI 1SGDI 3PDNA 4WP4A 1LR8A 5FUYA 2B8TA 2V1CC 1Z7KB 1YU6C 1CT4I 5HQ8A 3E59A 1WGCA 5HI7A 2GKTI 5E3PA 1PTRA 3B4VC 2SGQI 1S20A 1XX6A 1SGRI 1TOTA 2F3CI 4SGBI 5DAEA 1TIHA 3GOXA 1WTJA 2RC4A 1CT0I 2N1AB 3R5AA 2ARPF 3FC3A 1K7TA
chains in the Genus database with same CATH topology
1CGJI 2ENZA 2DIPA 2KMOA 2SGPI 4B6DA 1DS3I 1UVGA 2E73A 2N71A 1PTQA 3QTLD 2NU0I 2M5XA 3SGQI 1OVOA 2A20A 2VRWB 3QWPA 3UEYA 2W0TA 1M8BA 2JZMA 4A24A 1KMAA 3E2IA 5EX3A 1SGPI 1UVFA 1IW4A 1X4SA 2GVIA 1CHOI 3BJIA 2WVJA 2ERWA 2OVOA 2ROWA 3VDPA 2JW6A 2P6AC 2XRCA 1KBFA 4L9MA 1RFHA 3UEJA 2ELIA 1SGQI 2KMQA 5EX0A 2KCXA 3RU0A 2WCYA 1AN1I 1N13A 2K9HA 2QQDA 2LUYA 4HGUA 2KMPA 2YUUA 2BUSA 2QQCA 2GKVA 2QQ0A 3OL0A 1DS2I 4FKDA 3MEKA 2NU1I 1HPTA 1U5KA 2JXDA 1V1IA 2SGDI 1CT2I 1TUSA 2J9RA 3SEKC 1MT1A 1LR7A 4E1PA 2V1CA 3UGIA 2L8EA 1XA6A 1TBRR 1R79A 1FAQA 2NU2I 2QQEA 1TGSI 1W3SA 1VDDA 1CE3A 1OMUA 1TBQR 1SGNI 4UXHA 2FNFX 2JYYA 1OYVI 1Y8FA 1OMTA 2UZ3A 2E5RA 5FUVA 5JHWC 1BUSA 5CCMA 2ENNA 2GKRI 5FUWA 1CGII 1FARA 2J87A 4E1RA 3OXGA 3VE5A 2SGEI 2N17A 1IY6A 1TBOA 2ODDA 4JCVE 1V1HA 2N52A 4UXIA 4GI3C 1NUBA 3UGDA 1H0ZA 2B0UC 2NU3I 2KMRA 1SGYI 1Y1BA 3OVOA 2DB6A 2OD1A 2L7XA 2CJSC 4UXJA 5FUXA 2V53A 1FYBA 2NU4I 1XBTA 3KY9A 3OXFA 1PCEA 3D00A 1UUCA 1LR9A 1X74A 1R0RI 3TJQA 1TURA 2SGFI 3CXLA 3VDUA 2ORVA 1HDLA 2LEOA 3OXLA 3UFFA 1TBNA 1Y1CA 2QPOA 1YTPA 1W4RA 1PPFI 1CSOI 3SGBI 1HJAI 1PJUA 1KBEA 2JA1A 1IY5A 2YQPA 4OVOA 3UGLA 2ORWA 3PDNA 1BMOA 1M8CA 5CCLA 3HH2C 1SGEI 1SGDI 5FUYA 1LR8A 2B8TA 2V1CC 1Z7KB 1YU6C 1CT4I 5HQ8A 3E59A 5HI7A 2GKTI 1PTRA 3B4VC 2SGQI 1XX6A 1SGRI 1TOTA 2F3CI 4SGBI 5DAEA 1TIHA 3GOXA 1CT0I 2N1AB 2ARPF 3FC3A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1CGJ I;  2KMO A;  2SGP I;  1DS3 I;  1UVG A;  2N71 A;  3QTL D;  3SGQ I;  2NU0 I;  2M5X A;  1OVO A;  1M8B A;  2JZM A;  1KMA A;  1SGP I;  1UVF A;  1IW4 A;  1CHO I;  2ERW A;  2OVO A;  2P6A C;  2XRC A;  1SGQ I;  2KMQ A;  2KCX A;  2WCY A;  1AN1 I;  1N13 A;  2QQD A;  4HGU A;  2KMP A;  2BUS A;  2QQC A;  2GKV A;  1DS2 I;  2NU1 I;  1HPT A;  2JXD A;  2SGD I;  1CT2 I;  1TUS A;  3SEK C;  1MT1 A;  1LR7 A;  1TBR R;  2NU2 I;  1TGS I;  1CE3 A;  1OMU A;  1TBQ R;  1SGN I;  1BUS A;  2JYY A;  1OYV I;  1OMT A;  5JHW C;  2GKR I;  1CGI I;  2SGE I;  2N17 A;  1IY6 A;  2N52 A;  4GI3 C;  1NUB A;  1H0Z A;  2B0U C;  2NU3 I;  2KMR A;  1SGY I;  1Y1B A;  3OVO A;  2V53 A;  1FYB A;  2NU4 I;  1PCE A;  1UUC A;  1LR9 A;  3TJQ A;  1R0R I;  1TUR A;  2SGF I;  1HDL A;  2LEO A;  1Y1C A;  1YTP A;  1PPF I;  1CSO I;  3SGB I;  1HJA I;  1PJU A;  1IY5 A;  4OVO A;  1BMO A;  1M8C A;  3HH2 C;  1SGE I;  1SGD I;  1LR8 A;  1Z7K B;  1YU6 C;  1CT4 I;  2GKT I;  3B4V C;  2SGQ I;  1SGR I;  2F3C I;  4SGB I;  5DAE A;  1TIH A;  1CT0 I;  2ARP F; 
#chains in the Genus database with same CATH topology
 1CGJ I;  2ENZ A;  2DIP A;  2KMO A;  2SGP I;  4B6D A;  1DS3 I;  1UVG A;  2E73 A;  2N71 A;  1PTQ A;  3QTL D;  2NU0 I;  2M5X A;  3SGQ I;  1OVO A;  2A20 A;  2VRW B;  3QWP A;  3UEY A;  2W0T A;  1M8B A;  2JZM A;  4A24 A;  1KMA A;  3E2I A;  1NXU A;  1SGP I;  1UVF A;  1MJA A;  1X4S A;  5EX3 A;  3TOB A;  1IW4 A;  1UHA A;  2GVI A;  1CHO I;  3BJI A;  2WVJ A;  1WKX A;  3TO9 A;  2ERW A;  1K7U A;  1ULM A;  2OVO A;  2ROW A;  2GIV A;  5J8F A;  3VDP A;  3R5B A;  2JW6 A;  2P6A C;  4MPI A;  2XRC A;  1KBF A;  4L9M A;  1RFH A;  3UEJ A;  4AML A;  2ELI A;  2RIJ A;  2OZU A;  1SGQ I;  2KMQ A;  5EX0 A;  1ULN A;  2KCX A;  2WCY A;  3RU0 A;  1AN1 I;  1N13 A;  2DKV A;  2K9H A;  2LUY A;  2QQD A;  4HGU A;  5E3Q A;  2KMP A;  2YUU A;  2BUS A;  2QQC A;  2GKV A;  1FY7 A;  2QQ0 A;  3OL0 A;  1DS2 I;  3FSY A;  1K7V A;  3MEK A;  4FKD A;  2NU1 I;  3TO7 A;  1HPT A;  1U5K A;  2JXD A;  1V1I A;  4DNC A;  2SGD I;  1CT2 I;  1P9Z A;  1TUS A;  1Q9B A;  2J9R A;  3UOE A;  3SEK C;  1MT1 A;  1LR7 A;  4E1P A;  2V1C A;  3UGI A;  2L8E A;  1XA6 A;  1WGT A;  3QAH A;  5E3R A;  1TBR R;  9WGA A;  1R79 A;  1FAQ A;  1ULK A;  2NU2 I;  1TGS I;  1W3S A;  1VDD A;  2QQE A;  1CE3 A;  1MJB A;  1OMU A;  1TBQ R;  2X52 A;  1SGN I;  4UXH A;  2FNF X;  2JYY A;  1OYV I;  1Y8F A;  1OMT A;  2UZ3 A;  2E5R A;  2CWH A;  5FUV A;  5JHW C;  1HEV A;  5CCM A;  2ENN A;  2GKR I;  5FUW A;  1CGI I;  2LB7 A;  1FAR A;  2J87 A;  4E1R A;  7WGA A;  3OXG A;  1MJ9 A;  2SGE I;  2N17 A;  3VE5 A;  2CWF A;  5J8C A;  1TBO A;  1IY6 A;  2ODD A;  4JCV E;  1V1H A;  2N52 A;  4UXI A;  4GI3 C;  3R5D A;  1NUB A;  3UGD A;  1H0Z A;  2B0U C;  3R5C A;  2NU3 I;  2KMR A;  1SGY I;  1Y1B A;  3OVO A;  2OU2 A;  2DB6 A;  2OD1 A;  2L7X A;  2CJS C;  4UXJ A;  5FUX A;  2V53 A;  1FYB A;  2NU4 I;  1XBT A;  3KY9 A;  3OXF A;  1BUS A;  1PCE A;  3D00 A;  1UUC A;  1LR9 A;  1X74 A;  1R0R I;  3TJQ A;  2Y0M A;  1TUR A;  2SGF I;  3CXL A;  3VDU A;  2ORV A;  1HDL A;  2LEO A;  3OXL A;  3UFF A;  1TBN A;  1Y1C A;  2QPO A;  3FSX A;  1YTP A;  1W4R A;  1PPF I;  2UVO A;  1P9G A;  3TOA A;  1CSO I;  3SGB I;  1HJA I;  1PJU A;  1KBE A;  2JA1 A;  3TO6 A;  1Z2I A;  5CCL A;  1IY5 A;  2CWG A;  2X3T A;  2YQP A;  4OVO A;  3UGL A;  2ORW A;  2PQ8 A;  1BMO A;  1M8C A;  2WGC A;  3HH2 C;  1SGE I;  1SGD I;  3PDN A;  4WP4 A;  1LR8 A;  5FUY A;  2B8T A;  2V1C C;  1Z7K B;  1YU6 C;  1CT4 I;  5HQ8 A;  3E59 A;  1WGC A;  5HI7 A;  2GKT I;  5E3P A;  1PTR A;  3B4V C;  2SGQ I;  1S20 A;  1XX6 A;  1SGR I;  1TOT A;  2F3C I;  4SGB I;  5DAE A;  1TIH A;  3GOX A;  1WTJ A;  2RC4 A;  1CT0 I;  2N1A B;  3R5A A;  2ARP F;  3FC3 A;  1K7T A; 
#chains in the Genus database with same CATH homology
 1CGJ I;  2ENZ A;  2DIP A;  2KMO A;  2SGP I;  4B6D A;  1DS3 I;  1UVG A;  2E73 A;  2N71 A;  1PTQ A;  3QTL D;  2NU0 I;  2M5X A;  3SGQ I;  1OVO A;  2A20 A;  2VRW B;  3QWP A;  3UEY A;  2W0T A;  1M8B A;  2JZM A;  4A24 A;  1KMA A;  3E2I A;  5EX3 A;  1SGP I;  1UVF A;  1IW4 A;  1X4S A;  2GVI A;  1CHO I;  3BJI A;  2WVJ A;  2ERW A;  2OVO A;  2ROW A;  3VDP A;  2JW6 A;  2P6A C;  2XRC A;  1KBF A;  4L9M A;  1RFH A;  3UEJ A;  2ELI A;  1SGQ I;  2KMQ A;  5EX0 A;  2KCX A;  3RU0 A;  2WCY A;  1AN1 I;  1N13 A;  2K9H A;  2QQD A;  2LUY A;  4HGU A;  2KMP A;  2YUU A;  2BUS A;  2QQC A;  2GKV A;  2QQ0 A;  3OL0 A;  1DS2 I;  4FKD A;  3MEK A;  2NU1 I;  1HPT A;  1U5K A;  2JXD A;  1V1I A;  2SGD I;  1CT2 I;  1TUS A;  2J9R A;  3SEK C;  1MT1 A;  1LR7 A;  4E1P A;  2V1C A;  3UGI A;  2L8E A;  1XA6 A;  1TBR R;  1R79 A;  1FAQ A;  2NU2 I;  2QQE A;  1TGS I;  1W3S A;  1VDD A;  1CE3 A;  1OMU A;  1TBQ R;  1SGN I;  4UXH A;  2FNF X;  2JYY A;  1OYV I;  1Y8F A;  1OMT A;  2UZ3 A;  2E5R A;  5FUV A;  5JHW C;  1BUS A;  5CCM A;  2ENN A;  2GKR I;  5FUW A;  1CGI I;  1FAR A;  2J87 A;  4E1R A;  3OXG A;  3VE5 A;  2SGE I;  2N17 A;  1IY6 A;  1TBO A;  2ODD A;  4JCV E;  1V1H A;  2N52 A;  4UXI A;  4GI3 C;  1NUB A;  3UGD A;  1H0Z A;  2B0U C;  2NU3 I;  2KMR A;  1SGY I;  1Y1B A;  3OVO A;  2DB6 A;  2OD1 A;  2L7X A;  2CJS C;  4UXJ A;  5FUX A;  2V53 A;  1FYB A;  2NU4 I;  1XBT A;  3KY9 A;  3OXF A;  1PCE A;  3D00 A;  1UUC A;  1LR9 A;  1X74 A;  1R0R I;  3TJQ A;  1TUR A;  2SGF I;  3CXL A;  3VDU A;  2ORV A;  1HDL A;  2LEO A;  3OXL A;  3UFF A;  1TBN A;  1Y1C A;  2QPO A;  1YTP A;  1W4R A;  1PPF I;  1CSO I;  3SGB I;  1HJA I;  1PJU A;  1KBE A;  2JA1 A;  1IY5 A;  2YQP A;  4OVO A;  3UGL A;  2ORW A;  3PDN A;  1BMO A;  1M8C A;  5CCL A;  3HH2 C;  1SGE I;  1SGD I;  5FUY A;  1LR8 A;  2B8T A;  2V1C C;  1Z7K B;  1YU6 C;  1CT4 I;  5HQ8 A;  3E59 A;  5HI7 A;  2GKT I;  1PTR A;  3B4V C;  2SGQ I;  1XX6 A;  1SGR I;  1TOT A;  2F3C I;  4SGB I;  5DAE A;  1TIH A;  3GOX A;  1CT0 I;  2N1A B;  2ARP F;  3FC3 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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