2WCYA

Nmr solution structure of factor i-like modules of complement c7.
Total Genus 27
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
27
sequence length
155
structure length
155
Chain Sequence
GSHMNPLTQAVPKCQRWEKLQNSRCVCKMPYECGPSLDVCAQDERSKRILPLTVCKMHVLHCQGRNYTLTGRDSCTLPASAEKACGACPLWGKCDAESSKCVCREASECEEEGFSICVEVNGKEQTMSECEAGALRCRGQSISVTSIRPCAAETQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Immune system
molecule keywords COMPLEMENT COMPONENT C7
publication title Solution Structure of Factor I-Like Modules from Complement C7 Reveals a Pair of Follistatin Domains in Compact Pseudosymmetric Arrangement.
pubmed doi rcsb
source organism Homo sapiens
total genus 27
structure length 155
sequence length 155
ec nomenclature
pdb deposition date 2009-03-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF18434 Kazal_3 Kazal-type serine protease inhibitor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.60.30 Alpha Beta 2-Layer Sandwich Wheat Germ Agglutinin (Isolectin 2); domain 1 Wheat Germ Agglutinin (Isolectin 2); domain 1 2wcyA01
3.30.60.30 Alpha Beta 2-Layer Sandwich Wheat Germ Agglutinin (Isolectin 2); domain 1 Wheat Germ Agglutinin (Isolectin 2); domain 1 2wcyA02
1YU6C 2N52A 1MT1A 1TIHA 2SGFI 5JHWC 1CE3A 2N71A 1CT4I 2SGPI 2KMOA 1CT0I 1Y1BA 4OVOA 1SGNI 2ERWA 3OVOA 1TURA 1IY5A 1R0RI 1OYVI 2GKRI 1TGSI 2N17A 2KMPA 2KMRA 1Z7KB 1LR8A 1SGEI 1M8CA 2F3CI 4SGBI 1IY6A 1SGRI 2NU0I 2GKTI 1BUSA 2NU3I 1UVGA 1N13A 2QQDA 1CGII 1HDLA 1OMUA 2LEOA 4HGUA 1CT2I 2GKVA 3QTLD 2XRCA 1OVOA 2WCYA 2V53A 1HPTA 1DS3I 2NU2I 4GI3C 1AN1I 1CHOI 1SGYI 1TBRR 1TUSA 5DAEA 2M5XA 2NU4I 1LR9A 1CSOI 1PPFI 1H0ZA 2JZMA 1LR7A 1OMTA 3SGBI 2ARPF 1CGJI 1SGDI 2B0UC 2JYYA 1SGPI 1IW4A 1DS2I 1UVFA 1BMOA 2P6AC 2BUSA 1HJAI 1UUCA 1TBQR 2KCXA 2SGDI 3B4VC 3SEKC 1PJUA 2KMQA 1NUBA 1M8BA 3TJQA 1PCEA 2NU1I 3HH2C 1SGQI 2SGQI 2JXDA 2SGEI 1YTPA 2QQCA 1FYBA 3SGQI 1Y1CA 2OVOA 1KMAA
chains in the Genus database with same CATH superfamily
1YU6C 1X4SA 2N52A 2W0TA 2V1CC 3E59A 1MT1A 1TIHA 2SGFI 2J9RA 5FUWA 5JHWC 4WP4A 2L7XA 1P9GA 1CE3A 1HEVA 1P9ZA 1XBTA 3TOBA 1MJ9A 2V1CA 2N71A 2ORWA 3D00A 2OU2A 5CCLA 1XA6A 2X3TA 5HQ8A 2JA1A 2QPOA 9WGAA 1CT4I 2SGPI 1U5KA 2FNFX 1CT0I 1PTQA 2KMOA 1Y1BA 2A20A 5E3PA 4A24A 5J8FA 4OVOA 2ORVA 1Z2IA 1SGNI 2UVOA 5J8CA 2ERWA 1PTRA 2PQ8A 3OVOA 1TURA 4UXJA 4B6DA 1FAQA 1IY5A 1R0RI 1OYVI 1V1HA 2GKRI 2X52A 1X74A 1TGSI 2N17A 2QQ0A 2RIJA 2E73A 2WVJA 2KMPA 2DIPA 1WGCA 2ELIA 2CWFA 2KMRA 5FUYA 3UFFA 4MPIA 1Z7KB 3UOEA 1LR8A 1SGEI 1M8CA 3R5AA 2YUUA 4E1PA 1K7TA 2F3CI 5E3QA 2E5RA 4SGBI 1IY6A 4AMLA 1SGRI 1V1IA 2DB6A 2NU0I 1KBEA 3R5BA 3R5CA 5FUXA 2WGCA 3R5DA 2OZUA 3UEYA 3OXFA 2GKTI 1BUSA 2GIVA 1W3SA 1S20A 1ULMA 2NU3I 1UVGA 1N13A 3CXLA 2OD1A 2K9HA 1WKXA 2J87A 3BJIA 3TO7A 1Y8FA 4DNCA 3QWPA 2QQDA 1CGII 1HDLA 3OXGA 1OMUA 2LEOA 3FSXA 4HGUA 4L9MA 7WGAA 1CT2I 3OXLA 2GKVA 4FKDA 3QTLD 2XRCA 1MJBA 1OVOA 2CWHA 2ENZA 2QQEA 2WCYA 3PDNA 2V53A 1HPTA 3OL0A 3QAHA 1Q9BA 1DS3I 2RC4A 2LUYA 2B8TA 1XX6A 2CWGA 2NU2I 2YQPA 1AN1I 1CHOI 1SGYI 1ULKA 4GI3C 3TO6A 1TBRR 1TUSA 5DAEA 2M5XA 2NU4I 3UGDA 1MJAA 5HI7A 1LR9A 4UXIA 1CSOI 1R79A 1WTJA 1PPFI 2ROWA 2Y0MA 2JZMA 3FSYA 3UGIA 4E1RA 1LR7A 1H0ZA 1OMTA 2LB7A 2ODDA 3SGBI 3TO9A 3TOAA 2ARPF 3MEKA 4UXHA 1CGJI 1SGDI 1TBNA 1TOTA 2B0UC 1SGPI 2JYYA 3VE5A 1IW4A 1DS2I 1UVFA 2GVIA 1BMOA 1ULNA 2L8EA 1FY7A 2P6AC 2BUSA 1HJAI 5FUVA 1UUCA 2N1AB 1FARA 1TBQR 1UHAA 2ENNA 2KCXA 2SGDI 3B4VC 3UEJA 1KBFA 3SEKC 5CCMA 1PJUA 2KMQA 1K7VA 1TBOA 5EX0A 1NUBA 1RFHA 3RU0A 1M8BA 3TJQA 3E2IA 3KY9A 2DKVA 2JW6A 1PCEA 1VDDA 2NU1I 3HH2C 1SGQI 1NXUA 2VRWB 2UZ3A 3GOXA 2SGQI 2JXDA 3UGLA 2SGEI 4JCVE 1W4RA 1YTPA 1WGTA 2QQCA 3FC3A 3VDUA 1FYBA 5E3RA 5EX3A 3SGQI 1Y1CA 3VDPA 2OVOA 1KMAA 2CJSC 1K7UA
chains in the Genus database with same CATH topology
1YU6C 1X4SA 2N52A 2W0TA 2V1CC 3E59A 1MT1A 1TIHA 2SGFI 2J9RA 5FUWA 5JHWC 2L7XA 1CE3A 1XBTA 2V1CA 2N71A 2ORWA 3D00A 5CCLA 1XA6A 5HQ8A 2JA1A 2QPOA 1CT4I 2SGPI 1U5KA 2FNFX 1CT0I 1PTQA 2KMOA 1Y1BA 2A20A 4A24A 4OVOA 2ORVA 1SGNI 2ERWA 1PTRA 3OVOA 1TURA 4UXJA 4B6DA 1FAQA 1IY5A 1R0RI 1OYVI 1V1HA 2GKRI 1X74A 1TGSI 2N17A 2QQ0A 2WVJA 2E73A 2KMPA 2ELIA 2KMRA 5FUYA 3UFFA 1Z7KB 1LR8A 1SGEI 1M8CA 2YUUA 4E1PA 2F3CI 2E5RA 4SGBI 1IY6A 1SGRI 1V1IA 2DB6A 2NU0I 1KBEA 5FUXA 3UEYA 3OXFA 2GKTI 1BUSA 1W3SA 2NU3I 1UVGA 1N13A 3CXLA 2OD1A 2K9HA 2J87A 3BJIA 1Y8FA 3QWPA 2QQDA 1CGII 1HDLA 3OXGA 1OMUA 2LEOA 4HGUA 4L9MA 1CT2I 3OXLA 2GKVA 4FKDA 3QTLD 2XRCA 1OVOA 2ENZA 2QQEA 2WCYA 3PDNA 2V53A 1HPTA 3OL0A 1DS3I 2LUYA 2B8TA 1XX6A 2NU2I 2YQPA 1AN1I 1CHOI 1SGYI 4GI3C 1TBRR 1TUSA 5DAEA 2M5XA 2NU4I 3UGDA 5HI7A 1LR9A 4UXIA 1CSOI 1R79A 2ROWA 1PPFI 3UGIA 3VDUA 2JZMA 4E1RA 1H0ZA 1LR7A 1OMTA 3SGBI 2ODDA 2ARPF 3MEKA 4UXHA 1CGJI 1SGDI 1TBNA 1TOTA 2B0UC 1SGPI 2JYYA 3VE5A 1IW4A 1DS2I 1UVFA 2GVIA 1BMOA 2L8EA 2P6AC 2BUSA 1HJAI 5FUVA 1UUCA 2N1AB 1FARA 1TBQR 2ENNA 2KCXA 2SGDI 3UEJA 3B4VC 1KBFA 3SEKC 5CCMA 1PJUA 2KMQA 5EX0A 1TBOA 1NUBA 1RFHA 3RU0A 1M8BA 3TJQA 3E2IA 3KY9A 2JW6A 1PCEA 1VDDA 2NU1I 3HH2C 1SGQI 2VRWB 2UZ3A 3GOXA 2SGQI 2JXDA 3UGLA 2SGEI 4JCVE 1W4RA 1YTPA 2QQCA 3FC3A 1FYBA 5EX3A 3SGQI 1Y1CA 3VDPA 2OVOA 1KMAA 2CJSC 2DIPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1YU6 C;  2N52 A;  1MT1 A;  1TIH A;  2SGF I;  5JHW C;  1CE3 A;  2N71 A;  1CT4 I;  2SGP I;  2KMO A;  1CT0 I;  1Y1B A;  4OVO A;  1SGN I;  2ERW A;  3OVO A;  1TUR A;  1IY5 A;  1R0R I;  1OYV I;  2GKR I;  1TGS I;  2N17 A;  2KMP A;  2KMR A;  1Z7K B;  1LR8 A;  1SGE I;  1M8C A;  2F3C I;  4SGB I;  1IY6 A;  1SGR I;  2NU0 I;  2GKT I;  1BUS A;  2NU3 I;  1UVG A;  1N13 A;  2QQD A;  1CGI I;  1HDL A;  1OMU A;  2LEO A;  4HGU A;  1CT2 I;  2GKV A;  3QTL D;  2XRC A;  1OVO A;  2WCY A;  2V53 A;  1HPT A;  1DS3 I;  2NU2 I;  4GI3 C;  1AN1 I;  1CHO I;  1SGY I;  1TBR R;  1TUS A;  5DAE A;  2M5X A;  2NU4 I;  1LR9 A;  1CSO I;  1PPF I;  1H0Z A;  2JZM A;  1LR7 A;  1OMT A;  3SGB I;  2ARP F;  1CGJ I;  1SGD I;  2B0U C;  2JYY A;  1SGP I;  1IW4 A;  1DS2 I;  1UVF A;  1BMO A;  2P6A C;  2BUS A;  1HJA I;  1UUC A;  1TBQ R;  2KCX A;  2SGD I;  3B4V C;  3SEK C;  1PJU A;  2KMQ A;  1NUB A;  1M8B A;  3TJQ A;  1PCE A;  2NU1 I;  3HH2 C;  1SGQ I;  2SGQ I;  2JXD A;  2SGE I;  1YTP A;  2QQC A;  1FYB A;  3SGQ I;  1Y1C A;  2OVO A;  1KMA A; 
#chains in the Genus database with same CATH topology
 1YU6 C;  1X4S A;  2N52 A;  2W0T A;  2V1C C;  3E59 A;  1MT1 A;  1TIH A;  2SGF I;  2J9R A;  5FUW A;  5JHW C;  4WP4 A;  2L7X A;  1P9G A;  1CE3 A;  1HEV A;  1P9Z A;  1XBT A;  3TOB A;  1MJ9 A;  2V1C A;  2N71 A;  2ORW A;  3D00 A;  2OU2 A;  5CCL A;  1XA6 A;  2X3T A;  5HQ8 A;  2JA1 A;  2QPO A;  9WGA A;  1CT4 I;  2SGP I;  1U5K A;  2FNF X;  1CT0 I;  1PTQ A;  2KMO A;  1Y1B A;  2A20 A;  5E3P A;  4A24 A;  5J8F A;  4OVO A;  2ORV A;  1Z2I A;  1SGN I;  2UVO A;  5J8C A;  2ERW A;  1PTR A;  2PQ8 A;  3OVO A;  1TUR A;  4UXJ A;  4B6D A;  1FAQ A;  1IY5 A;  1R0R I;  1OYV I;  1V1H A;  2GKR I;  2X52 A;  1X74 A;  1TGS I;  2N17 A;  2QQ0 A;  2RIJ A;  2E73 A;  2WVJ A;  2KMP A;  2DIP A;  1WGC A;  2ELI A;  2CWF A;  2KMR A;  5FUY A;  3UFF A;  4MPI A;  1Z7K B;  3UOE A;  1LR8 A;  1SGE I;  1M8C A;  3R5A A;  2YUU A;  4E1P A;  1K7T A;  2F3C I;  5E3Q A;  2E5R A;  4SGB I;  1IY6 A;  4AML A;  1SGR I;  1V1I A;  2DB6 A;  2NU0 I;  1KBE A;  3R5B A;  3R5C A;  5FUX A;  2WGC A;  3R5D A;  2OZU A;  3UEY A;  3OXF A;  2GKT I;  1BUS A;  2GIV A;  1W3S A;  1S20 A;  1ULM A;  2NU3 I;  1UVG A;  1N13 A;  3CXL A;  2OD1 A;  2K9H A;  1WKX A;  2J87 A;  3BJI A;  3TO7 A;  1Y8F A;  4DNC A;  3QWP A;  2QQD A;  1CGI I;  1HDL A;  3OXG A;  1OMU A;  2LEO A;  3FSX A;  4HGU A;  4L9M A;  7WGA A;  1CT2 I;  3OXL A;  2GKV A;  4FKD A;  3QTL D;  2XRC A;  1MJB A;  1OVO A;  2CWH A;  2ENZ A;  2QQE A;  2WCY A;  3PDN A;  2V53 A;  1HPT A;  3OL0 A;  3QAH A;  1Q9B A;  1DS3 I;  2RC4 A;  2LUY A;  2B8T A;  1XX6 A;  2CWG A;  2NU2 I;  2YQP A;  1AN1 I;  1CHO I;  1SGY I;  1ULK A;  4GI3 C;  3TO6 A;  1TBR R;  1TUS A;  5DAE A;  2M5X A;  2NU4 I;  3UGD A;  1MJA A;  5HI7 A;  1LR9 A;  4UXI A;  1CSO I;  1R79 A;  1WTJ A;  1PPF I;  2ROW A;  2Y0M A;  2JZM A;  3FSY A;  3UGI A;  4E1R A;  1LR7 A;  1H0Z A;  1OMT A;  2LB7 A;  2ODD A;  3SGB I;  3TO9 A;  3TOA A;  2ARP F;  3MEK A;  4UXH A;  1CGJ I;  1SGD I;  1TBN A;  1TOT A;  2B0U C;  1SGP I;  2JYY A;  3VE5 A;  1IW4 A;  1DS2 I;  1UVF A;  2GVI A;  1BMO A;  1ULN A;  2L8E A;  1FY7 A;  2P6A C;  2BUS A;  1HJA I;  5FUV A;  1UUC A;  2N1A B;  1FAR A;  1TBQ R;  1UHA A;  2ENN A;  2KCX A;  2SGD I;  3B4V C;  3UEJ A;  1KBF A;  3SEK C;  5CCM A;  1PJU A;  2KMQ A;  1K7V A;  1TBO A;  5EX0 A;  1NUB A;  1RFH A;  3RU0 A;  1M8B A;  3TJQ A;  3E2I A;  3KY9 A;  2DKV A;  2JW6 A;  1PCE A;  1VDD A;  2NU1 I;  3HH2 C;  1SGQ I;  1NXU A;  2VRW B;  2UZ3 A;  3GOX A;  2SGQ I;  2JXD A;  3UGL A;  2SGE I;  4JCV E;  1W4R A;  1YTP A;  1WGT A;  2QQC A;  3FC3 A;  3VDU A;  1FYB A;  5E3R A;  5EX3 A;  3SGQ I;  1Y1C A;  3VDP A;  2OVO A;  1KMA A;  2CJS C;  1K7U A; 
#chains in the Genus database with same CATH homology
 1YU6 C;  1X4S A;  2N52 A;  2W0T A;  2V1C C;  3E59 A;  1MT1 A;  1TIH A;  2SGF I;  2J9R A;  5FUW A;  5JHW C;  2L7X A;  1CE3 A;  1XBT A;  2V1C A;  2N71 A;  2ORW A;  3D00 A;  5CCL A;  1XA6 A;  5HQ8 A;  2JA1 A;  2QPO A;  1CT4 I;  2SGP I;  1U5K A;  2FNF X;  1CT0 I;  1PTQ A;  2KMO A;  1Y1B A;  2A20 A;  4A24 A;  4OVO A;  2ORV A;  1SGN I;  2ERW A;  1PTR A;  3OVO A;  1TUR A;  4UXJ A;  4B6D A;  1FAQ A;  1IY5 A;  1R0R I;  1OYV I;  1V1H A;  2GKR I;  1X74 A;  1TGS I;  2N17 A;  2QQ0 A;  2WVJ A;  2E73 A;  2KMP A;  2ELI A;  2KMR A;  5FUY A;  3UFF A;  1Z7K B;  1LR8 A;  1SGE I;  1M8C A;  2YUU A;  4E1P A;  2F3C I;  2E5R A;  4SGB I;  1IY6 A;  1SGR I;  1V1I A;  2DB6 A;  2NU0 I;  1KBE A;  5FUX A;  3UEY A;  3OXF A;  2GKT I;  1BUS A;  1W3S A;  2NU3 I;  1UVG A;  1N13 A;  3CXL A;  2OD1 A;  2K9H A;  2J87 A;  3BJI A;  1Y8F A;  3QWP A;  2QQD A;  1CGI I;  1HDL A;  3OXG A;  1OMU A;  2LEO A;  4HGU A;  4L9M A;  1CT2 I;  3OXL A;  2GKV A;  4FKD A;  3QTL D;  2XRC A;  1OVO A;  2ENZ A;  2QQE A;  2WCY A;  3PDN A;  2V53 A;  1HPT A;  3OL0 A;  1DS3 I;  2LUY A;  2B8T A;  1XX6 A;  2NU2 I;  2YQP A;  1AN1 I;  1CHO I;  1SGY I;  4GI3 C;  1TBR R;  1TUS A;  5DAE A;  2M5X A;  2NU4 I;  3UGD A;  5HI7 A;  1LR9 A;  4UXI A;  1CSO I;  1R79 A;  2ROW A;  1PPF I;  3UGI A;  3VDU A;  2JZM A;  4E1R A;  1H0Z A;  1LR7 A;  1OMT A;  3SGB I;  2ODD A;  2ARP F;  3MEK A;  4UXH A;  1CGJ I;  1SGD I;  1TBN A;  1TOT A;  2B0U C;  1SGP I;  2JYY A;  3VE5 A;  1IW4 A;  1DS2 I;  1UVF A;  2GVI A;  1BMO A;  2L8E A;  2P6A C;  2BUS A;  1HJA I;  5FUV A;  1UUC A;  2N1A B;  1FAR A;  1TBQ R;  2ENN A;  2KCX A;  2SGD I;  3UEJ A;  3B4V C;  1KBF A;  3SEK C;  5CCM A;  1PJU A;  2KMQ A;  5EX0 A;  1TBO A;  1NUB A;  1RFH A;  3RU0 A;  1M8B A;  3TJQ A;  3E2I A;  3KY9 A;  2JW6 A;  1PCE A;  1VDD A;  2NU1 I;  3HH2 C;  1SGQ I;  2VRW B;  2UZ3 A;  3GOX A;  2SGQ I;  2JXD A;  3UGL A;  2SGE I;  4JCV E;  1W4R A;  1YTP A;  2QQC A;  3FC3 A;  1FYB A;  5EX3 A;  3SGQ I;  1Y1C A;  3VDP A;  2OVO A;  1KMA A;  2CJS C;  2DIP A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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