3UGIA

Structural and functional characterization of an anesthetic binding site in the second cysteine-rich domain of protein kinase c delta
Total Genus 11
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
11
sequence length
65
structure length
65
Chain Sequence
GSRRASVGSHRFKVYNYMSPTFCDHCGSLLWGLVKQGLKCEDCGMNVHHKCREKVANLCEFIVTD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural and Functional Characterization of an Anesthetic Binding Site in the Second Cysteine-Rich Domain of Protein Kinase Cdelta
pubmed doi rcsb
molecule tags Metal binding protein
source organism Mus musculus
molecule keywords Protein kinase C delta type
total genus 11
structure length 65
sequence length 65
chains with identical sequence B
ec nomenclature ec 2.7.10.2: Non-specific protein-tyrosine kinase.
pdb deposition date 2011-11-02
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.60.20 Alpha Beta 2-Layer Sandwich Wheat Germ Agglutinin (Isolectin 2); domain 1 Wheat Germ Agglutinin (Isolectin 2); domain 1 3ugiA01
2ENZA 4B6DA 5FUXA 2WVJA 1XA6A 3BJIA 3CXLA 2ORWA 2J9RA 2ROWA 1Y8FA 3UEYA 1PTRA 1W4RA 1RFHA 2JA1A 2ENNA 2J87A 2ORVA 2VRWB 1XX6A 4L9MA 1R79A 1TBOA 2FNFX 3UGLA 3UEJA 1XBTA 4UXHA 3UGDA 2QPOA 1TBNA 2DB6A 1FAQA 5FUYA 2YUUA 1KBEA 1KBFA 3KY9A 4UXIA 4UXJA 2B8TA 2GVIA 1FARA 2UZ3A 5FUWA 3E2IA 2E73A 4FKDA 2ELIA 1PTQA 2QQ0A 3UGIA 2QQEA 5FUVA 3UFFA
chains in the Genus database with same CATH superfamily
1Q9BA 1SGDI 1Z2IA 2ENZA 2KMOA 2N1AB 2LUYA 1HDLA 2OU2A 2J9RA 4MPIA 5E3QA 1LR9A 3TJQA 5EX3A 1PTRA 2CWFA 2QQDA 2JA1A 2SGQI 2J87A 2LB7A 2ORVA 3R5AA 4E1RA 2VRWB 1CT0I 1NXUA 2N71A 2NU3I 3SGQI 2RC4A 4DNCA 2A20A 5EX0A 2RIJA 3UGDA 2BUSA 2NU1I 7WGAA 1WTJA 1CT2I 3FSYA 3UOEA 2YUUA 1OMUA 2L7XA 1IW4A 1LR7A 2M5XA 1TOTA 4UXJA 2GVIA 2UZ3A 1K7TA 2K9HA 5DAEA 2ERWA 1SGNI 3D00A 4JCVE 2LEOA 5HI7A 2OZUA 1TBRR 1VDDA 1SGPI 2QQEA 4E1PA 1M8BA 2CWHA 1XA6A 1PPFI 3BJIA 3FSXA 1X74A 1W4RA 1NUBA 1SGEI 2ENNA 2N17A 3QTLD 1K7UA 3OXLA 1P9ZA 2KMQA 1XX6A 3E59A 1UHAA 2F3CI 2SGEI 5JHWC 3UGLA 1MJ9A 5CCLA 1UVGA 1HPTA 2X3TA 1CE3A 1CHOI 3RU0A 2NU2I 3OVOA 1FARA 1TBQR 3TO6A 1BUSA 3TO9A 3MEKA 3R5DA 4AMLA 5HQ8A 2JZMA 2JW6A 4SGBI 3VDUA 2SGFI 1Y1BA 2KCXA 5FUVA 3R5BA 1UUCA 1MJBA 1ULKA 1N13A 1Z7KB 1YTPA 1PCEA 1OYVI 2ARPF 3CXLA 3VE5A 1CGII 3R5CA 5E3RA 3TO7A 2ROWA 1Y8FA 1WGTA 1YU6C 1WGCA 3OL0A 1CT4I 1SGRI 4OVOA 2JYYA 2GKRI 2GKVA 3B4VC 1W3SA 5CCMA 1OMTA 2E5RA 4L9MA 4A24A 1TBOA 2FNFX 1XBTA 4UXHA 1IY5A 3GOXA 2N52A 5FUYA 1SGQI 1KMAA 1FY7A 3OXFA 1TUSA 2NU4I 1BMOA 2CJSC 2SGDI 5E3PA 3SEKC 2OD1A 3PDNA 1MJAA 1X4SA 1UVFA 3KY9A 4UXIA 1H0ZA 2B8TA 3SGBI 1U5KA 5FUWA 3E2IA 2E73A 2W0TA 4FKDA 2DIPA 2P6AC 1OVOA 1PTQA 2Y0MA 3QWPA 1HJAI 4WP4A 4GI3C 2KMPA 3UFFA 1PJUA 1CSOI 3FC3A 1DS3I 1ULNA 1Y1CA 2V1CA 3QAHA 2KMRA 2WVJA 5FUXA 4B6DA 1AN1I 2SGPI 1ULMA 2ORWA 1FYBA 1R0RI 3UEYA 5J8CA 2UVOA 1V1IA 1RFHA 1MT1A 1TIHA 3TOAA 5J8FA 2NU0I 1WKXA 1IY6A 3HH2C 2B0UC 2CWGA 1K7VA 1DS2I 1R79A 2X52A 1SGYI 3UEJA 2QPOA 1TBNA 2DB6A 3VDPA 1V1HA 1FAQA 1HEVA 1KBEA 2GIVA 2WGCA 2V53A 1KBFA 1P9GA 2V1CC 2DKVA 3TOBA 2PQ8A 1LR8A 1M8CA 1TGSI 2GKTI 2WCYA 2L8EA 2YQPA 2OVOA 1TURA 1S20A 2XRCA 2ELIA 4HGUA 2ODDA 2QQ0A 3UGIA 9WGAA 1CGJI 2JXDA 3OXGA 2QQCA
chains in the Genus database with same CATH topology
1SGDI 2KMOA 2ENZA 2N1AB 2LUYA 1HDLA 2J9RA 1LR9A 3TJQA 5EX3A 1PTRA 2QQDA 2JA1A 2SGQI 2J87A 2ORVA 4E1RA 2VRWB 1CT0I 2N71A 2NU3I 3SGQI 2A20A 5EX0A 3UGDA 2BUSA 2NU1I 1CT2I 2YUUA 1OMUA 2L7XA 1IW4A 1LR7A 2M5XA 1TOTA 4UXJA 2GVIA 2UZ3A 2K9HA 5DAEA 2ERWA 1SGNI 3D00A 4JCVE 2LEOA 5HI7A 2QQEA 1TBRR 1VDDA 1SGPI 4E1PA 1M8BA 1XA6A 1PPFI 3BJIA 1X74A 1W4RA 1NUBA 1SGEI 2ENNA 2N17A 3QTLD 3OXLA 2KMQA 1XX6A 3E59A 2F3CI 2SGEI 5JHWC 3UGLA 5CCLA 1UVGA 1HPTA 1CE3A 1CHOI 3RU0A 2NU2I 3OVOA 1FARA 1TBQR 1BUSA 3MEKA 5HQ8A 2JZMA 2JW6A 4SGBI 3VDUA 2SGFI 1Y1BA 2KCXA 5FUVA 1UUCA 1Z7KB 1N13A 2ARPF 1YTPA 1PCEA 1OYVI 3VE5A 3CXLA 1CGII 2ROWA 1Y8FA 1YU6C 3OL0A 1CT4I 1SGRI 4OVOA 2JYYA 2GKRI 2GKVA 3B4VC 1W3SA 5CCMA 1OMTA 2E5RA 4L9MA 4A24A 1TBOA 2FNFX 1XBTA 4UXHA 1IY5A 3GOXA 2N52A 5FUYA 1SGQI 1KMAA 3OXFA 1TUSA 2NU4I 1BMOA 2CJSC 2SGDI 3SEKC 2OD1A 3PDNA 1X4SA 3KY9A 1UVFA 4UXIA 1H0ZA 2B8TA 3SGBI 1U5KA 5FUWA 3E2IA 2E73A 2W0TA 4FKDA 2DIPA 2P6AC 1OVOA 1PTQA 3QWPA 1HJAI 4GI3C 2KMPA 3UFFA 1PJUA 1CSOI 3FC3A 1DS3I 1Y1CA 2V1CA 4B6DA 2KMRA 2WVJA 5FUXA 1AN1I 2SGPI 2ORWA 1FYBA 1R0RI 3UEYA 1V1IA 1RFHA 1MT1A 1TIHA 2NU0I 1IY6A 3HH2C 2B0UC 1R79A 1DS2I 1SGYI 3UEJA 2QPOA 1TBNA 2DB6A 3VDPA 1V1HA 1FAQA 1KBEA 2V53A 1KBFA 2V1CC 1M8CA 1LR8A 1TGSI 2GKTI 2WCYA 2L8EA 2YQPA 2OVOA 1TURA 2XRCA 2ELIA 4HGUA 2ODDA 2QQ0A 3UGIA 1CGJI 2JXDA 3OXGA 2QQCA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2ENZ A;  4B6D A;  5FUX A;  2WVJ A;  1XA6 A;  3BJI A;  3CXL A;  2ORW A;  2J9R A;  2ROW A;  1Y8F A;  3UEY A;  1PTR A;  1W4R A;  1RFH A;  2JA1 A;  2ENN A;  2J87 A;  2ORV A;  2VRW B;  1XX6 A;  4L9M A;  1R79 A;  1TBO A;  2FNF X;  3UGL A;  3UEJ A;  1XBT A;  4UXH A;  3UGD A;  2QPO A;  1TBN A;  2DB6 A;  1FAQ A;  5FUY A;  2YUU A;  1KBE A;  1KBF A;  3KY9 A;  4UXI A;  4UXJ A;  2B8T A;  2GVI A;  1FAR A;  2UZ3 A;  5FUW A;  3E2I A;  2E73 A;  4FKD A;  2ELI A;  1PTQ A;  2QQ0 A;  3UGI A;  2QQE A;  5FUV A;  3UFF A; 
#chains in the Genus database with same CATH topology
 1Q9B A;  1SGD I;  1Z2I A;  2ENZ A;  2KMO A;  2N1A B;  2LUY A;  1HDL A;  2OU2 A;  2J9R A;  4MPI A;  5E3Q A;  1LR9 A;  3TJQ A;  5EX3 A;  1PTR A;  2CWF A;  2QQD A;  2JA1 A;  2SGQ I;  2J87 A;  2LB7 A;  2ORV A;  3R5A A;  4E1R A;  2VRW B;  1CT0 I;  1NXU A;  2N71 A;  2NU3 I;  3SGQ I;  2RC4 A;  4DNC A;  2A20 A;  5EX0 A;  2RIJ A;  3UGD A;  2BUS A;  2NU1 I;  7WGA A;  1WTJ A;  1CT2 I;  3FSY A;  3UOE A;  2YUU A;  1OMU A;  2L7X A;  1IW4 A;  1LR7 A;  2M5X A;  1TOT A;  4UXJ A;  2GVI A;  2UZ3 A;  1K7T A;  2K9H A;  5DAE A;  2ERW A;  1SGN I;  3D00 A;  4JCV E;  2LEO A;  5HI7 A;  2OZU A;  1TBR R;  1VDD A;  1SGP I;  2QQE A;  4E1P A;  1M8B A;  2CWH A;  1XA6 A;  1PPF I;  3BJI A;  3FSX A;  1X74 A;  1W4R A;  1NUB A;  1SGE I;  2ENN A;  2N17 A;  3QTL D;  1K7U A;  3OXL A;  1P9Z A;  2KMQ A;  1XX6 A;  3E59 A;  1UHA A;  2F3C I;  2SGE I;  5JHW C;  3UGL A;  1MJ9 A;  5CCL A;  1UVG A;  1HPT A;  2X3T A;  1CE3 A;  1CHO I;  3RU0 A;  2NU2 I;  3OVO A;  1FAR A;  1TBQ R;  3TO6 A;  1BUS A;  3TO9 A;  3MEK A;  3R5D A;  4AML A;  5HQ8 A;  2JZM A;  2JW6 A;  4SGB I;  3VDU A;  2SGF I;  1Y1B A;  2KCX A;  5FUV A;  3R5B A;  1UUC A;  1MJB A;  1ULK A;  1N13 A;  1Z7K B;  1YTP A;  1PCE A;  1OYV I;  2ARP F;  3CXL A;  3VE5 A;  1CGI I;  3R5C A;  5E3R A;  3TO7 A;  2ROW A;  1Y8F A;  1WGT A;  1YU6 C;  1WGC A;  3OL0 A;  1CT4 I;  1SGR I;  4OVO A;  2JYY A;  2GKR I;  2GKV A;  3B4V C;  1W3S A;  5CCM A;  1OMT A;  2E5R A;  4L9M A;  4A24 A;  1TBO A;  2FNF X;  1XBT A;  4UXH A;  1IY5 A;  3GOX A;  2N52 A;  5FUY A;  1SGQ I;  1KMA A;  1FY7 A;  3OXF A;  1TUS A;  2NU4 I;  1BMO A;  2CJS C;  2SGD I;  5E3P A;  3SEK C;  2OD1 A;  3PDN A;  1MJA A;  1X4S A;  1UVF A;  3KY9 A;  4UXI A;  1H0Z A;  2B8T A;  3SGB I;  1U5K A;  5FUW A;  3E2I A;  2E73 A;  2W0T A;  4FKD A;  2DIP A;  2P6A C;  1OVO A;  1PTQ A;  2Y0M A;  3QWP A;  1HJA I;  4WP4 A;  4GI3 C;  2KMP A;  3UFF A;  1PJU A;  1CSO I;  3FC3 A;  1DS3 I;  1ULN A;  1Y1C A;  2V1C A;  3QAH A;  2KMR A;  2WVJ A;  5FUX A;  4B6D A;  1AN1 I;  2SGP I;  1ULM A;  2ORW A;  1FYB A;  1R0R I;  3UEY A;  5J8C A;  2UVO A;  1V1I A;  1RFH A;  1MT1 A;  1TIH A;  3TOA A;  5J8F A;  2NU0 I;  1WKX A;  1IY6 A;  3HH2 C;  2B0U C;  2CWG A;  1K7V A;  1DS2 I;  1R79 A;  2X52 A;  1SGY I;  3UEJ A;  2QPO A;  1TBN A;  2DB6 A;  3VDP A;  1V1H A;  1FAQ A;  1HEV A;  1KBE A;  2GIV A;  2WGC A;  2V53 A;  1KBF A;  1P9G A;  2V1C C;  2DKV A;  3TOB A;  2PQ8 A;  1LR8 A;  1M8C A;  1TGS I;  2GKT I;  2WCY A;  2L8E A;  2YQP A;  2OVO A;  1TUR A;  1S20 A;  2XRC A;  2ELI A;  4HGU A;  2ODD A;  2QQ0 A;  3UGI A;  9WGA A;  1CGJ I;  2JXD A;  3OXG A;  2QQC A; 
#chains in the Genus database with same CATH homology
 1SGD I;  2KMO A;  2ENZ A;  2N1A B;  2LUY A;  1HDL A;  2J9R A;  1LR9 A;  3TJQ A;  5EX3 A;  1PTR A;  2QQD A;  2JA1 A;  2SGQ I;  2J87 A;  2ORV A;  4E1R A;  2VRW B;  1CT0 I;  2N71 A;  2NU3 I;  3SGQ I;  2A20 A;  5EX0 A;  3UGD A;  2BUS A;  2NU1 I;  1CT2 I;  2YUU A;  1OMU A;  2L7X A;  1IW4 A;  1LR7 A;  2M5X A;  1TOT A;  4UXJ A;  2GVI A;  2UZ3 A;  2K9H A;  5DAE A;  2ERW A;  1SGN I;  3D00 A;  4JCV E;  2LEO A;  5HI7 A;  2QQE A;  1TBR R;  1VDD A;  1SGP I;  4E1P A;  1M8B A;  1XA6 A;  1PPF I;  3BJI A;  1X74 A;  1W4R A;  1NUB A;  1SGE I;  2ENN A;  2N17 A;  3QTL D;  3OXL A;  2KMQ A;  1XX6 A;  3E59 A;  2F3C I;  2SGE I;  5JHW C;  3UGL A;  5CCL A;  1UVG A;  1HPT A;  1CE3 A;  1CHO I;  3RU0 A;  2NU2 I;  3OVO A;  1FAR A;  1TBQ R;  1BUS A;  3MEK A;  5HQ8 A;  2JZM A;  2JW6 A;  4SGB I;  3VDU A;  2SGF I;  1Y1B A;  2KCX A;  5FUV A;  1UUC A;  1Z7K B;  1N13 A;  2ARP F;  1YTP A;  1PCE A;  1OYV I;  3VE5 A;  3CXL A;  1CGI I;  2ROW A;  1Y8F A;  1YU6 C;  3OL0 A;  1CT4 I;  1SGR I;  4OVO A;  2JYY A;  2GKR I;  2GKV A;  3B4V C;  1W3S A;  5CCM A;  1OMT A;  2E5R A;  4L9M A;  4A24 A;  1TBO A;  2FNF X;  1XBT A;  4UXH A;  1IY5 A;  3GOX A;  2N52 A;  5FUY A;  1SGQ I;  1KMA A;  3OXF A;  1TUS A;  2NU4 I;  1BMO A;  2CJS C;  2SGD I;  3SEK C;  2OD1 A;  3PDN A;  1X4S A;  3KY9 A;  1UVF A;  4UXI A;  1H0Z A;  2B8T A;  3SGB I;  1U5K A;  5FUW A;  3E2I A;  2E73 A;  2W0T A;  4FKD A;  2DIP A;  2P6A C;  1OVO A;  1PTQ A;  3QWP A;  1HJA I;  4GI3 C;  2KMP A;  3UFF A;  1PJU A;  1CSO I;  3FC3 A;  1DS3 I;  1Y1C A;  2V1C A;  4B6D A;  2KMR A;  2WVJ A;  5FUX A;  1AN1 I;  2SGP I;  2ORW A;  1FYB A;  1R0R I;  3UEY A;  1V1I A;  1RFH A;  1MT1 A;  1TIH A;  2NU0 I;  1IY6 A;  3HH2 C;  2B0U C;  1R79 A;  1DS2 I;  1SGY I;  3UEJ A;  2QPO A;  1TBN A;  2DB6 A;  3VDP A;  1V1H A;  1FAQ A;  1KBE A;  2V53 A;  1KBF A;  2V1C C;  1M8C A;  1LR8 A;  1TGS I;  2GKT I;  2WCY A;  2L8E A;  2YQP A;  2OVO A;  1TUR A;  2XRC A;  2ELI A;  4HGU A;  2ODD A;  2QQ0 A;  3UGI A;  1CGJ I;  2JXD A;  3OXG A;  2QQC A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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